265 results match your criteria Cytomegalovirus Esophagitis


Mononeuritis multiplex: an uncommon neurological manifestation of cytomegalovirus reactivation in an HIV-infected patient.

BMC Infect Dis 2018 Nov 12;18(1):554. Epub 2018 Nov 12.

Infectious Diseases Department, Centro Hospitalar de São João, Alameda Professor Hernâni Monteiro, 4200-319, Porto, Portugal.

Background: Cytomegalovirus (CMV) reactivation with neurological involvement in patients with acquired immunodeficiency syndrome (AIDS) is increasingly rare since the introduction of antiretroviral therapy (ART). Manifestations include encephalitis, myelitis, polyradiculopathy and, less commonly, mononeuritis multiplex (MNM). We report a case of disseminated CMV disease with gastrointestinal and peripheral and central nervous system involvement in a patient with AIDS, manifesting primarily as MNM. Read More

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https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128
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http://dx.doi.org/10.1186/s12879-018-3501-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233374PMC
November 2018
21 Reads

Cytomegalovirus pleuropericarditis after orthotopic liver transplantation.

Acta Gastroenterol Belg 2018 Jul-Sep;81(3):427-429

Antwerp University Hospital, Department of Gastroenterology and Hepatology.

Cytomegalovirus (CMV) reactivation is a common complication after liver transplantation. In patients with CMV infection, indicated by a positive CMV DNA titer, the presence of any clinical symptom is termed CMV disease. The most common organ affected in CMV disease is the gastrointestinal tract, causing esophagitis, gastritis, enteritis or colitis. Read More

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February 2019
5 Reads

Infections of the esophagus: an update on risk factors, diagnosis, and management.

Dis Esophagus 2018 Dec;31(12)

Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.

Infectious esophagitis is a leading cause of esophagitis worldwide. While esophageal infections have traditionally been associated with immunocompromised patients, these disorders are becoming increasingly recognized in immunocompetent individuals. The three most common etiologies of infectious esophagitis are Candida, herpes simplex virus, and cytomegalovirus. Read More

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https://academic.oup.com/dote/advance-article/doi/10.1093/do
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http://dx.doi.org/10.1093/dote/doy094DOI Listing
December 2018
22 Reads

Fatal disseminated cytomegalovirus infection with necrotizing oophoritis in a patient with acquired immunodeficiency syndrome.

Autops Case Rep 2018 Jul-Sep;8(3):e2018029. Epub 2018 Jul 30.

Universidade de São Paulo, Faculty of Medicine, Department of Anatomic Pathology, Emergency Department and LIM06. São Paulo, SP, Brazil.

Disseminated human cytomegalovirus (CMV) disease occurs mainly as a congenital infection and among immunocompromised hosts. Patients with acquired immunodeficiency syndrome (AIDS) are at increased risk for CMV infection, and the most prevalent clinical manifestation is retinitis, followed by colitis, esophagitis, pneumonitis, and encephalitis. CMV oophoritis is poorly described in the literature with some cases reported in patients with hematological or solid malignancies, bone marrow or solid organ transplantation, immunosuppressive therapy, and advanced AIDS cases. Read More

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http://autopsyandcasereports.org/article/doi/10.4322/acr.201
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http://dx.doi.org/10.4322/acr.2018.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066265PMC
July 2018
16 Reads

Unique causes of esophageal inflammation: a histopathologic perspective.

Ann N Y Acad Sci 2018 Dec 16;1434(1):219-226. Epub 2018 May 16.

Department of Pathology, Yale School of Medicine, New Haven, Connecticut.

Gastroenterologists frequently perform endoscopic esophageal mucosal biopsies for pathologic diagnosis in patients experiencing symptoms of esophagitis. The more common causes of esophagitis diagnosed on esophageal mucosal biopsy include reflux esophagitis, eosinophilic esophagitis, and infectious esophagitis caused by Candida albicans, herpes simplex virus, and/or cytomegalovirus. However, there are several causes of esophagitis seen less frequently by pathologists that are very important to recognize. Read More

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http://dx.doi.org/10.1111/nyas.13732DOI Listing
December 2018
4 Reads

Role of Endoscopic Findings and Biopsies in Renal Transplant Recipients With Gastrointestinal Complications: A Tertiary Care Experience.

Exp Clin Transplant 2018 10 9;16(5):522-527. Epub 2018 Mar 9.

From the Department of Hepato-Gastroenterology, Sindh Institute of Urology and Transplantation, Karachi, Pakistan.

Objectives: We investigated the incidence of gastrointestinal disorders requiring endoscopic and histopathologic diagnoses in renal transplant recipients.

Materials And Methods: In this retrospective analysis, we examined records of patients seen at the Department of Hepato-Gastroenterology and Transplantation Sciences, Sindh Institute of Urology and Trans?lantation (Karachi, Pakistan) from January 2010 to December 2014. Renal transplant recipients with gastrointestinal disorders who required endoscopy, including proctoscopy and upper and lower gastrointestinal endoscopy as per indication, were included. Read More

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http://dx.doi.org/10.6002/ect.2017.0132DOI Listing
October 2018
11 Reads

Cytomegalovirus ulcerative oesophagitis in a young healthy immunocompetent patient.

BMJ Case Rep 2018 Mar 5;2018. Epub 2018 Mar 5.

Department of Gastroenterology, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.

Cytomegalovirus (CMV) gastrointestinal disease usually arises in patients with immunodeficiency or immunosuppression, being rare in immunocompetent hosts. Although increasing in incidence, few cases of CMV gastrointestinal disease have been described among young healthy patients. Currently, there is uncertainty in approaching these patients, including the need for antiviral therapy that remains to be established. Read More

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http://dx.doi.org/10.1136/bcr-2017-223297DOI Listing
March 2018
2 Reads

A rare presentation of cytomegalovirus infection in an immunocompetent patient.

Gastrointest Endosc 2018 07 17;88(1):185-186. Epub 2018 Mar 17.

Gastroenterology Department, Centro Hospitalar Tondela-Viseu, Viseu, Portugal.

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http://dx.doi.org/10.1016/j.gie.2018.01.037DOI Listing
July 2018
2 Reads

Early post-transplant diagnosis of cytomegalovirus esophagitis in an ABO-incompatible kidney transplant recipients: A case report.

Transpl Infect Dis 2018 Apr 25;20(2):e12827. Epub 2018 Jan 25.

Department of Nephrology and Hypertension, St. Marianna University School of Medicine, Kawasaki, Japan.

Cytomegalovirus (CMV) is a common infectious pathogen in kidney transplant patients. Here, we present a case of CMV esophagitis with antigenemia, that developed within 3 days of kidney transplantation, a timeline generally considered to be too early for development of a CMV infection. Intense immunosuppressive therapy for desensitization in ABO-incompatibility or in the presence of donor-specific antibody can increase the risk for significant opportunistic infection immediately after or even before transplantation. Read More

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http://dx.doi.org/10.1111/tid.12827DOI Listing
April 2018
41 Reads

Cytomegalovirus Disease of the Upper Gastrointestinal Tract: A 10-Year Retrospective Study.

GE Port J Gastroenterol 2017 Nov 2;24(6):262-268. Epub 2017 Sep 2.

Department of Gastroenterology, Lisbon, Portugal.

Background And Aims: Cytomegalovirus (CMV) disease of the gastrointestinal (GI) tract is a major cause of morbidity and mortality in immunocompromised patients. The colon is the most commonly affected site, and the literature is scarce regarding CMV disease of the upper GI tract. Therefore, our study aimed to evaluate the clinical and endoscopic features of upper GI CMV disease. Read More

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http://dx.doi.org/10.1159/000479232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731150PMC
November 2017
7 Reads

Severe esophagitis associated with cytomegalovirus during concurrent chemoradiotherapy for esophageal cancer.

Jpn J Clin Oncol 2017 Sep;47(9):885-888

Department of Clinical Oncology, Kyoto University Hospital, Kyoto, Japan.

Although radiation esophagitis is one of the most common adverse events that occurs during chemoradiotherapy (CRT) in patients with esophageal cancer, CRT-associated cytomegalovirus (CMV) esophagitis is rare. CMV esophagitis typically occurs in patients with an immunosuppressed status. Here we report a case of CMV esophagitis during CRT initially treated as radiation esophagitis. Read More

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http://dx.doi.org/10.1093/jjco/hyx083DOI Listing
September 2017
38 Reads

Varicella-Zoster Virus Gastritis: Case Report and Review of the Literature.

Int J Surg Pathol 2017 Aug 1;25(5):449-452. Epub 2017 Mar 1.

1 University of Calgary, Calgary, Alberta, Canada.

We report varicella-zoster virus (VZV) gastritis in a 70-year-old woman postchemotherapy for lymphoma, presenting with abdominal pain, vomiting, and delirium without rash. A gastric biopsy demonstrated viral inclusions but posed a diagnostic challenge as immunohistochemistry for cytomegalovirus and herpes simplex virus were negative, and VZV immunohistochemistry was not available. The patient developed a vesicular rash 7 days after her symptoms began. Read More

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http://journals.sagepub.com/doi/10.1177/1066896917696751
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http://dx.doi.org/10.1177/1066896917696751DOI Listing
August 2017
13 Reads

Celiac Crisis Associated with Herpes Simplex Virus Esophagitis.

ACG Case Rep J 2016 Aug 23;3(4):e159. Epub 2016 Nov 23.

Division of Gastroenterology, Hepatology, and Nutrition, The Ohio State University, Columbus, OH.

Celiac crisis is a rare presentation of celiac disease that is characterized by life-threatening electrolyte abnormalities, vitamin and mineral deficiencies, and diarrhea. Triggers for celiac crisis include major surgeries, pancreatitis, and infections of cytomegalovirus, and salmonella. A 24-year-old woman presented with celiac crisis associated with severe herpes simplex virus (HSV) esophagitis. Read More

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http://dx.doi.org/10.14309/crj.2016.132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126499PMC
August 2016
7 Reads
1 Citation

Periesophageal Pseudoaneurysms: Rare Cause of Refractory Bleeding Treated with Transarterial Embolization.

Case Rep Gastrointest Med 2016 12;2016:1456949. Epub 2016 Oct 12.

Division of Gastroenterology and Hepatology, Virginia Commonwealth University, Richmond, VA, USA.

A 43-year-old female with history of systemic lupus erythematosus, prior cytomegalovirus esophagitis treated with ganciclovir, and long segment Barrett's esophagus (Prague class C8 M9) with high grade dysplasia treated with radiofrequency ablation presented to the hospital with hematemesis. An upper gastrointestinal endoscopy showed multiple esophageal ulcers with active arterial spurting which could not be controlled with endoscopic interventions including placement of hemostatic clips. An emergent angiogram demonstrated actively bleeding saccular dilations (pseudoaneurysms) in the esophageal branches of the lower thoracic aorta as well as left gastric artery for which gelfoam and coil embolization was initially successful. Read More

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http://dx.doi.org/10.1155/2016/1456949DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080469PMC
October 2016
3 Reads

Cytomegalovirus esophagitis developing during chemoradiotherapy for esophageal cancer: two case reports.

J Med Case Rep 2016 Sep 21;10(1):259. Epub 2016 Sep 21.

Department of Gastroenterology, National Center of Global Health and Medicine, 1-21-1 Toyama Shinjuku-ku, Tokyo, 162-8655, Japan.

Background: It is well known that cytomegalovirus esophagitis occurs in immunosuppressed patients. However, few reports have described cytomegalovirus esophagitis occurring during chemoradiotherapy for esophageal cancer.

Case Presentation: We report two cases of patients with cytomegalovirus esophagitis that developed during chemoradiotherapy for esophageal cancer. Read More

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http://jmedicalcasereports.biomedcentral.com/articles/10.118
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http://dx.doi.org/10.1186/s13256-016-0947-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031298PMC
September 2016
6 Reads

Esophagitis Caused by Cytomegalovirus Infection in an Immune-competent Patient.

Clin Gastroenterol Hepatol 2016 12 29;14(12):e143-e144. Epub 2016 Jun 29.

Department of Gastroenterology, Sendai Kousei Hospital, Sendai-City, Miyagi, Japan.

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http://dx.doi.org/10.1016/j.cgh.2016.06.016DOI Listing
December 2016
6 Reads

Care of Patients With HIV Infection: Medical Complications and Comorbidities.

FP Essent 2016 Apr;443:16-22

University of Massachusetts Medical School, 55 N Lake Ave, Worcester, MA 01655.

Care of patients with HIV infection starts with diagnosis as soon as possible, preferably at or near the time of acute infection. Opportunistic infections, malignancies, and other conditions develop progressively over time, particularly in untreated patients. The AIDS-defining opportunistic infections most common in the United States include Pneumocystis jirovecii pneumonia, Candida esophagitis, toxoplasmic encephalitis, tuberculosis, disseminated Mycobacterium avium complex, cryptococcal meningitis, and cytomegalovirus retinitis. Read More

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April 2016
26 Reads

Evaluation and Management of Infectious Esophagitis in Immunocompromised and Immunocompetent Individuals.

Curr Treat Options Gastroenterol 2016 Mar;14(1):28-38

Division of Gastroenterology and Hepatology, Johns Hopkins University School of Medicine, 4940 Eastern Avenue, A Building, Room 344B, Baltimore, MD, 21224, USA.

Opinion Statement: Among the many inflammatory processes that may account for esophageal symptoms, infection represents an important etiologic category with numerous clinically relevant subdivisions. While features of the history and physical exam are informative, diagnosis often hinges on endoscopic visualization and histopathologic analysis. This chapter will review in series the most clinically relevant causative agents for infectious esophagitis, with specific diagnostic and therapeutic features of note divided into one of two immune milieus. Read More

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http://dx.doi.org/10.1007/s11938-016-0082-2DOI Listing
March 2016
7 Reads

Extensive Esophageal Ulceration in a Renal Transplant Patient.

GE Port J Gastroenterol 2016 Mar-Apr;23(2):116-118. Epub 2015 Oct 9.

Gastroenterology Department, Centro Hospitalar São João, Faculty of Medicine of the University of Porto, Porto, Portugal.

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http://dx.doi.org/10.1016/j.jpge.2015.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580169PMC
October 2015
3 Reads

Surgical manifestations of gastrointestinal cytomegalovirus infection in children: Clinical audit and literature review.

J Pediatr Surg 2015 Nov 30;50(11):1874-9. Epub 2015 Jun 30.

Department of Paediatric Surgery, Red Cross War Memorial Children's Hospital, Cape Town, South Africa.

Introduction: Gastrointestinal sequelae of cytomegalovirus are rare, usually associated with significant immune compromise, and carry a high morbidity and mortality. Gastrointestinal disease frequently requires surgical intervention for diagnosis and management.

Aim: The aim of the study is to evaluate the incidence, presentation and management of gastrointestinal cytomegalovirus disease in a pediatric population. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2015.06.018DOI Listing
November 2015
19 Reads

Esophageal infections: an update.

Curr Opin Pediatr 2015 Oct;27(5):642-8

aDivision of Infectious Disease and Immunology, Department of Pediatrics bDivision of Gastroenterology, Hepatology and Nutrition, Levine Children's Hospital, Carolinas Medical Center, Charlotte, North Carolina, USA.

Purpose Of Review: Infectious esophagitis generally occurs in patients with impaired immunity. Although methods to suppress the immune system evolve, the potential infectious consequences are poorly understood. The purpose of this article is to review the risk factors, diagnosis, and treatment of infectious esophagitis. Read More

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http://dx.doi.org/10.1097/MOP.0000000000000266DOI Listing
October 2015
5 Reads

Radiation esophagitis.

Arch Pathol Lab Med 2015 Jun;139(6):827-30

From the Department of Pathology, Rush University Medical Center, Chicago, Illinois.

The esophagus is frequently exposed to radiation during treatment of advanced stages of common cancers such as lung, breast, and esophagus. However, symptomatic radiation esophagitis requiring endoscopic and histologic evaluation occurs quite rarely, affecting less than 1% of patients receiving radiation treatment. Symptoms occur acutely, generally within the first 2 months. Read More

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http://www.archivesofpathology.org/doi/10.5858/arpa.2014-011
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http://dx.doi.org/10.5858/arpa.2014-0111-RSDOI Listing
June 2015
10 Reads

Symptomatic cytomegalovirus gastrointestinal infection with positive quantitative real-time PCR findings in apparently immunocompetent patients: a case series.

Clin Microbiol Infect 2015 Dec 22;21(12):1121.e1-7. Epub 2015 May 22.

University Clinic of Geriatric Medicine, Grenoble University Hospital, Grenoble, France.

Cytomegalovirus (CMV) gastrointestinal disease rarely occurs in immunocompetent patients, and is mainly diagnosed on the basis of histopathological findings. Real-time PCR for CMV DNA quantification is considered to be a useful diagnostic tool, but its place in the diagnostic strategy is not clearly defined. The goal of the study was to describe the clinical and paraclinical features of apparently immunocompetent patients with CMV gastrointestinal disease diagnosed according to quantitative PCR results. Read More

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http://dx.doi.org/10.1016/j.cmi.2015.05.016DOI Listing
December 2015
2 Reads

Severe viral oesophagitis, pharyngitis, and stomatitis as antecedents of ileocecal Crohn's disease.

Prz Gastroenterol 2015 6;10(1):47-50. Epub 2015 Feb 6.

Department of Gastroenterology and Hepatology, Medical University of Silesia, Katowice, Poland.

We present a 22-year-old male who developed a severe erosive oesophagitis extending to the pharynx and oral cavity without obvious risk factors. Endoscopic image suggested viral aetiology that could not be confirmed by routine serological diagnostics of infections with cytomegalovirus, Epstein-Barr virus, and Herpes simplex virus. The histopathological evaluation also gave no definite clues to the aetiology of the inflammation. Read More

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http://dx.doi.org/10.5114/pg.2014.47495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411404PMC
May 2015
8 Reads

Acyclovir versus valganciclovir for preventing cytomegalovirus infection in intermediate-risk liver transplant recipients.

Prog Transplant 2015 Mar;25(1):39-44

Hartford Hospital, Hartford, Connecticut.

Context: Cytomegalovirus (CMV) is an opportunistic infection that causes profound morbidity and mortality after orthotopic liver transplant (OLT). The CMV immunoglobulin G serostatuses of donors and recipients are the main factors influencing risk for development of CMV infection after transplant.

Objective: To compare acyclovir and valganciclovir for preventing CMV infection after OLT. Read More

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http://dx.doi.org/10.7182/pit2015558DOI Listing
March 2015
8 Reads

Catastrophic gastrointestinal complication of systemic immunosuppression.

World J Gastroenterol 2015 Feb;21(8):2542-5

Lyn Alexandra Smith, Daniel R Gaya, Gastroenterology Unit, Glasgow Royal Infirmary, G4 0SF Glasgow, United Kingdom.

We present a case of acute upper gastrointestinal haemorrhage in a patient with systemic vasculitis immunosuppressed on cyclophosphamide and prednisolone. The patient presented with a diffuse haemorrhagic oesophagitis and a non-specific duodenitis. Biopsies taken from the oesophagus and duodenum demonstrated infection with herpes simplex virus (HSV) and cytomegalovirus (CMV) respectively. Read More

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http://www.wjgnet.com/1007-9327/full/v21/i8/2542.htm
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http://dx.doi.org/10.3748/wjg.v21.i8.2542DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342934PMC
February 2015
7 Reads

The clinical characteristics and manifestations of cytomegalovirus esophagitis.

Dis Esophagus 2016 May 26;29(4):392-9. Epub 2015 Feb 26.

Department of Pathology, Chang Gung Memorial Hospital, Taoyuan, Taiwan.

Esophagitis is the second most common gastrointestinal manifestation of cytomegalovirus (CMV) infection after colitis. CMV esophagitis has been reported in patients who have undergone transplantation, are on long-term renal dialysis, or who have the human immunodeficiency virus infection. This study aimed to investigate the clinical characteristics and manifestations of CMV esophagitis in patients who underwent diagnostic endoscopy. Read More

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http://dx.doi.org/10.1111/dote.12340DOI Listing
May 2016
33 Reads

Cytomegalovirus esophagitis in an immunocompetent patient: case report.

Turk J Gastroenterol 2014 Oct;25(5):571-4

Institute for Digestive Research, Soonchunhyang University College of Medicine, Seoul, Republic of Korea.

Cytomegalovirus (CMV) esophagitis is well-documented in immunocompromised patients. A few studies have described CMV infection in immunocompetent patients diagnosed with a critical illness. However, CMV esophagitis has rarely been documented in immunocompetent hosts. Read More

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http://dx.doi.org/10.5152/tjg.2014.4073DOI Listing
October 2014
10 Reads

Is it possible to diagnose infectious oesophagitis without seeing the causative organism? A histopathological study.

Turk J Gastroenterol 2014 Oct;25(5):481-7

Department of Pathology, Ege University Faculty of Medicine, İzmir, Turkey.

Background/aims: We investigated the utility of using histological changes to diagnose infectious oesophagitis when causative organisms cannot be seen.

Materials And Methods: Sixty-seven endoscopic biopsy specimens (51 Candida, 9 herpes simplex virus, 4 tuberculosis, and 3 cytomegalovirus oesophagitis) collected from 2000-2010 that matched the investigative criteria were included in the study. Cases were re-evaluated for histological changes observed in oesophagitis, and the findings were statistically compared using nonparametric tests. Read More

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http://dx.doi.org/10.5152/tjg.2014.4967DOI Listing
October 2014
19 Reads

Small bowel transplantation complicated by cytomegalovirus tissue invasive disease without viremia.

J Clin Virol 2014 Jun 15;60(2):177-80. Epub 2014 Mar 15.

Department of Transplant Medicine, University Hospital Münster, Münster, Germany. Electronic address:

We report on a small bowel transplant patient, donor/recipient seropositive (D+/R+) for cytomegalovirus (CMV), with a clinical course complicated by CMV disease. Anti-CMV prophylaxis was given for 100 days. Immunosuppression consisted of alemtuzumab, tacrolimus, mycophenolate mofetil and prednisolone. Read More

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http://dx.doi.org/10.1016/j.jcv.2014.03.005DOI Listing
June 2014
5 Reads

AP-VAS 2012 case report: a case of ANCA-negative crescentic glomerulonephritis complicating multiple opportunistic infections in the digestive tract.

CEN Case Rep 2013 Nov 30;2(2):174-179. Epub 2013 Aug 30.

Department of Internal Medicine, Division of Nephrology, Otsu Red Cross Hospital, 1-1-35 Nagara, Otsu, Shiga, 520-8511, Japan.

Crescentic glomerulonephritis (GN) is one of the common causes of rapidly progressive glomerulonephritis (RPGN). Pauci-immune crescentic GN is usually associated with anti-neutrophil cytoplasmic antibody (ANCA). However, patients with pauci-immune crescentic GN who lack ANCAs have recently been reported. Read More

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http://dx.doi.org/10.1007/s13730-013-0091-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411559PMC
November 2013
3 Reads

[CMV-induced duodenal papillitis in a patient with HIV-1 infection].

Kansenshogaku Zasshi 2013 Jul;87(4):441-5

Internal Medicine, Clinical Research Institute, National Hospital Organization, Kyushu Medical Center.

We present herein a case report of a 59-year-old patient with HIV-1 infection who developed a CMV-induced pseudotumor of the duodenum. The patient presented with oral pain and dysphagia. Physical examination revealed oral thrush. Read More

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July 2013
7 Reads

Cytomegalovirus disease of the upper gastrointestinal tract in patients with rheumatic diseases: a case series and literature review.

Clin Rheumatol 2013 Nov 14;32(11):1683-90. Epub 2013 Aug 14.

Division of Rheumatic Diseases, National Center for Global Health and Medicine, 1-21-1, Toyama, Shinjuku-ku, Tokyo, 162-8655, Japan,

Cytomegalovirus disease of the upper gastrointestinal tract (CMV-UGT) is a rare but significant complication in patients with rheumatic diseases. We reviewed records for January 2004 to December 2012 and investigated the occurrence of CMV-UGT in patients with rheumatic diseases to evaluate clinical characteristics, the value of the CMV antigenemia assay, and the association between immunosuppressive therapy and CMV-UGT. Ten CMV-UGT events (six gastric ulcer, two esophagitis, one gastritis, and one duodenal ulcer) in nine patients (three rheumatoid arthritis, three systemic lupus erythematosus, one dermatomyositis, one systemic sclerosis, and one overlap syndrome) were identified based on pathology. Read More

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http://dx.doi.org/10.1007/s10067-013-2363-7DOI Listing
November 2013
14 Reads

Cytomegalovirus infection of the major duodenal papilla in a renal allograft recipient with severe biliary obstruction and acalculous cholecystitis.

Transpl Infect Dis 2013 Aug 23;15(4):E129-33. Epub 2013 Jun 23.

Department of Hepatology, University of Heidelberg, Heidelberg, Germany.

Cytomegalovirus (CMV) can cause severe infections with serious consequences in renal transplant recipients. Disseminated CMV infections can affect almost every organ, but obstructive cholestasis and cholangitis, as a consequence of a CMV-induced papillitis, is extremely rare. We are reporting a rare case of obstructive cholestasis and cholecystitis due to CMV-related inflammation of the major duodenal papilla in a 60-year-old woman 3 months after renal transplantation. Read More

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http://dx.doi.org/10.1111/tid.12105DOI Listing
August 2013
4 Reads

Cytomegalovirus esophagitis precipitated with immunosuppression in elderly giant cell arteritis patients.

Aging Clin Exp Res 2013 May 29;25(2):215-8. Epub 2013 Mar 29.

Division of Geriatrics, Department of Internal Medicine, Istanbul School of Medicine, Istanbul University, Capa, 34093, Istanbul, Turkey.

Cytomegalovirus (CMV) infection is generally associated with significant immunosuppression. Cellular immunity is particularly important and corticosteroid treatment increases the risk of CMV infection substantially. Immunocompetence generally decreases with age, older patients are at higher risk for developing CMV disease than are younger patients. Read More

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http://dx.doi.org/10.1007/s40520-013-0019-8DOI Listing
May 2013
13 Reads

Foscarnet-resistant cytomegalovirus esophagitis with stricturing.

Case Rep Gastroenterol 2013 Jan 10;7(1):25-9. Epub 2013 Jan 10.

Department of Medicine, Bronx Lebanon Hospital Center, Bronx, N.Y., USA.

We report the case of a 52-year-old man with HIV-AIDS, non-complaint with highly active antiretroviral therapy, who presented with long-standing dysphagia. He was treated for three episodes of severe Candida esophagitis with fluconazole and later caspofungin due to poor response. In spite of the prolonged treatment courses the patient did not report an improvement in his symptoms. Read More

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http://dx.doi.org/10.1159/000342352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573790PMC
January 2013
2 Reads

A clinicopathologic study of esophageal 860 benign and malignant lesions in 910 cases of consecutive esophageal biopsies.

Authors:
Tadashi Terada

Int J Clin Exp Pathol 2013 15;6(2):191-8. Epub 2013 Jan 15.

Department of Pathology, Shizuoka City Shimizu Hospital Shizuoka, Japan.

The author reviewed 910 cases of consecutive esophageal biopsies in the last 15 year in the pathology laboratory of our hospital. There were 693 normal mucosa and benign lesions (76.2%) and 217 malignant lesions (23. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544238PMC
July 2013
4 Reads

[Multi-organ failure in a patient with fungaemia due to Saprochaete capitata].

Rev Iberoam Micol 2013 Oct-Dec;30(4):261-3. Epub 2013 Jan 11.

Servicio de Cuidados Críticos y Urgencias, Hospital Juan Ramón Jiménez, Huelva, España. Electronic address:

Background: The significant increase in systemic fungal infections is mainly due to the increase in immunocompromised patients. The high morbimortality of these infections, along with the high hospitalization costs they generate, makes them a problem of great importance in our hospital practice. Saprochaete capitata is a rare fungus that causes invasive infections, usually in immunocompromised patients, and for which there is still no consensus on the treatment regimen to be used. Read More

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http://dx.doi.org/10.1016/j.riam.2012.12.003DOI Listing
August 2014
5 Reads

Etiology, diagnosis and treatment of infectious esophagitis.

Prz Gastroenterol 2013 30;8(6):333-7. Epub 2013 Dec 30.

2 Department of Internal Medicine and Gastroenterology, Międzyleski Specialist Hospital, Warsaw, Poland.

Infectious esophagitis may be caused by fungal, viral, bacterial or even parasitic agents. Risk factors include antibiotics and steroids use, chemotherapy and/or radiation therapy, malignancies and immunodeficiency syndromes including acquired immunodeficiency syndrome. Acute onset of symptoms such as dysphagia and odynophagia is typical. Read More

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http://dx.doi.org/10.5114/pg.2013.39914DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027832PMC
June 2014
5 Reads

Multiple viral infections after haploidentical hematopoietic stem cell transplantation in a child with acute lymphoblastic leukemia.

Transpl Infect Dis 2012 Oct 3;14(5):E82-8. Epub 2012 Aug 3.

Klinik für Kinder- und Jugendmedizin, Universitätsklinikum Jena, Friedrich-Schiller-Universität Jena, Jena, Germany.

After allogeneic hematopoietic stem cell transplantation (HSCT), viral infections/reactivations are a frequent complication, sometimes with fatal outcome. Thus, early diagnosis is recommended by screening of whole blood or plasma preparations using highly sensitive molecular techniques that test for the most common viral pathogens, such as Epstein-Barr virus, cytomegalovirus, and adenoviruses (ADVs). Despite this approach, not every reactivation/infection can be adequately detected or excluded, even with highly sensitive polymerase chain reaction. Read More

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http://dx.doi.org/10.1111/j.1399-3062.2012.00778.xDOI Listing
October 2012
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Cytomegalovirus oesophagitis following treatment with fludarabine for refractory lymphoplasmacytic lymphoma.

BMJ Case Rep 2012 Jul 5;2012. Epub 2012 Jul 5.

Milton Keynes General Hospital, Milton Keynes, UK.

A 64-year-old man with a 2-week history of fatigue and fever presented to the medical admissions unit. He had a background of lymphoplasmacytic lymphoma and had recently completed a course of fludarabine-based chemotherapy. CT of the abdomen demonstrated an increase in spleen size and it was thought that his fevers were most likely due to disease recurrence or high-grade transformation. Read More

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http://dx.doi.org/10.1136/bcr-2012-006235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543235PMC
July 2012
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Herpes and cytomegalovirus esophagitis.

Endoscopy 2012 19;44 Suppl 2 UCTN:E242-3. Epub 2012 Jun 19.

Gastroenterology Department, Hospital de São João, Porto, Portugal.

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http://dx.doi.org/10.1055/s-0032-1309385DOI Listing
October 2012
3 Reads

[Esophagitis during immunosuppression].

Authors:
F Moosig W L Gross

Z Rheumatol 2012 Jun;71(4):326-7

Poliklinik für Rheumatologie, Universität zu Lübeck und Klinikum Bad Bramstedt, Oskar-Alexander-Str. 26, 24576, Bad Bramstedt, Deutschland.

Esophagitis due to cytomegalovirus (CMV) has mostly been described in patients with acquired immunodeficiency syndrome (AIDS). Distal and hemorrhagic ulcerations are characteristic. A CMA esophagitis can, however, also occur in patients with no human immunodeficiency virus (HIV) infection as a complication of immunosuppressive therapy. Read More

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http://dx.doi.org/10.1007/s00393-012-0963-2DOI Listing
June 2012
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An unusual case of dysphagia.

Dig Liver Dis 2012 May 26;44(5):e9. Epub 2012 Jan 26.

Digestive Endoscopy, University Hospital, Messina, Italy.

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http://dx.doi.org/10.1016/j.dld.2011.12.002DOI Listing
May 2012
4 Reads