366 results match your criteria CytoJournal [Journal]


Cytology of the fallopian tube: A screening model for high-grade serous carcinoma.

Cytojournal 2018 12;15:28. Epub 2018 Nov 12.

Address: Department of Medical and Surgical Gynecology, Mayo Clinic, Jacksonville, FL, USA.

Ovarian cancer is a heterogeneous disease having the highest gynecologic fatality in the United States with a 5-year survival rate of 46.5%. Poor overall prognosis is mostly attributed to inadequate screening tools, and the majority of diagnoses occur at late stages of the disease. Read More

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November 2018
1 Read

Increased mast cells in endocervical smears of women with dysmenorrhea.

Cytojournal 2018 12;15:27. Epub 2018 Nov 12.

Address: Department of Obstetrics and Gynecology, Shiga University of Medical Science, Seta, Otsu, Shiga, Japan.

Background: Mast cells are observed in peritoneal endometriosis which causes dysmenorrhea. However, there is no report about the relationship between endocervical mast cells and dysmenorrhea. The aim of this study is to evaluate the relationship using endocervical smears. Read More

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November 2018

Cytologic examination of ascitic fluid in a patient with pleural-based mass: A unique presentation of a rare tumor.

Cytojournal 2018 15;15:26. Epub 2018 Oct 15.

Address: Department of Pathology and Radiology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.

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October 2018

Endometrial carcinoma with pleural fluid metastasis: A rare phenomenon.

Cytojournal 2018 15;15:25. Epub 2018 Oct 15.

Address: Department of Pathology, Post Graduate Institute of Medical Education and Research and Dr. Ram Manohar Lohia Hospital, New Delhi, India.

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October 2018

Correlation study of thyroid nodule cytopathology and histopathology at two institutions in Jordan.

Cytojournal 2018 15;15:24. Epub 2018 Oct 15.

Address: King Hussein Cancer Center, Department of Pathology and Laboratory Medicine, Al-Jubeiha, Amman 11941, Jordan.

Background: Fine-needle aspiration (FNA) plays a fundamental role in determining the appropriate management for patients presenting with thyroid nodules.

Aims: The aims of this study are to evaluate thyroid FNA test performance parameters through a cytohistological correlation.

Materials And Methods: A retrospective analysis of all thyroid FNAs received over a period of 18 months was carried out. Read More

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October 2018
6 Reads

Not all neck mass fine-needle aspirations with squamous cells are squamous cell carcinoma; report of a case of recurrent thyroid carcinoma with papillary and squamous components.

Cytojournal 2018 21;15:23. Epub 2018 Sep 21.

Address: Department of Pathology and Laboratory Medicine, University of Kansas School of Medicine, 3901 Rainbow Blvd, Kansas City, KS 66160, USA.

We report a case of a 65-year-old female who had a total thyroidectomy 12 years ago for papillary thyroid carcinoma (PTC) who presented with a recurrent thyroid bed mass. Fine-needle aspiration biopsy yielded malignant cells, consistent with squamous cell carcinoma (SCCa). Surgical resection was performed, and histologic evaluation of the mass showed mixed PTC and SCCa. Read More

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September 2018
1 Read

The Papanicolaou Society of Cytopathology guidelines for respiratory cytology: Reproducibility of categories among observers.

Cytojournal 2018 21;15:22. Epub 2018 Sep 21.

Department of Pathology and Arup Laboratories, University of Utah, Salt Lake City, UT 84112, USA.

Introduction: The Papanicolaou Society of Cytopathology (PSC) has developed a set of guidelines for reporting respiratory cytology. While the malignancy risk for each category is known, the interobserver reproducibility of these diagnostic categories has not been well described.

Methods: Fifty-five cytologic specimens obtained by fine needle aspiration from the pulmonary nodules were independently reviewed by four board-certified cytopathologists and assigned to the diagnostic categories described by the PSC guidelines for respiratory specimens. Read More

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September 2018
2 Reads

Lung tumor in a young African American patient with sickle trait: Pieces of a puzzle.

Cytojournal 2018 27;15:21. Epub 2018 Aug 27.

Address: Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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Cytological diagnosis of osteoblastoma of the talus: Case report with unusual presentation and diagnostic pitfalls.

Cytojournal 2018 27;15:20. Epub 2018 Aug 27.

Department of Orthopaedics, Himalayan Institute of Medical Sciences, Dehradun, Uttarakhand, India.

Osteoblastoma is a rare bone tumor mostly affecting the young adults and commonly involving the spinal cord and long bones. Talus is the uncommon site of presentation, and if involved, then the neck is more commonly involved than the body of talus. The cytological diagnosis of osteoblastoma is limited, and to the best of our knowledge, its fine-needle aspiration (FNA) in the talus has still not been reported in the literature. Read More

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August 2018
1 Read

Spectrum of clinicohematological profile and its correlation with average parasite density in visceral leishmaniasis.

Cytojournal 2018 27;15:19. Epub 2018 Aug 27.

Address: Department of Pathology, PGIMER, Dr. RML Hospital, New Delhi, India.

Background: Leishmaniasis is the prevalent in tropical and subtropical regions of the world. Demonstration of Leishman-Donovan (LD) bodies in the bone marrow aspirates (BMA) is vital to diagnosis of visceral leishmaniasis (VL). In the present study, we studied the clinicohematological parameters encountered in VL and correlated them with parasite load on BMA. Read More

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August 2018
1 Read

Cytodiagnosis of extramedullary hematopoiesis in serous effusion: A rare presentation unfolding the underlying etiology.

Cytojournal 2018 13;15:18. Epub 2018 Jul 13.

Address: Department of Pathology, Dr. RML Hospital, Post Graduate Institute of Medical Education and Research, New Delhi, India.

Extramedullary hematopoiesis (EMH) usually involves reticuloendothelial system. However, it rarely may be present in the serous body effusions. In our case, the fluid cytology of both peritoneal and pleural fluid was diagnostic of the EMH in a patient with an undiagnosed underlying etiology. Read More

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July 2018
1 Read

Adult exogenous lipoid pneumonia: A rare and underrecognized entity in cytology - A case series.

Cytojournal 2018 13;15:17. Epub 2018 Jul 13.

Address: Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, USA.

Background: Exogenous lipoid pneumonia (ELP) is a rare benign entity without specific clinical or imaging presentation. Although cytological studies - either bronchoalveolar lavage (BAL) or fine-needle aspiration (FNA) - may be pursued in patients with ELP, a definitive diagnosis is frequently rendered only on histology. The aim of this study is to highlight the cytological features of ELP. Read More

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July 2018
1 Read

Pleural effusion in a 7-year-old child - with unique cells.

Cytojournal 2018 13;15:16. Epub 2018 Jul 13.

Address: Department of Pathology and Laboratory Medicine, Hofstra Northwell School of Medicine, NY 11042, USA.

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July 2018
1 Read

Hematolymphoid neoplasms in effusion cytology.

Cytojournal 2018 14;15:15. Epub 2018 Jun 14.

Address: Department of Pathology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India.

Background: Hematolymphoid neoplasms (HLNs) presenting as body cavity effusions are not a common finding. They may be the first manifestation of the disease. A diagnosis on effusion cytology may provide an early breakthrough for effective clinical management. Read More

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Large retroperitoneal soft tissue tumor: A cytopathological diagnosis.

Cytojournal 2018 14;15:14. Epub 2018 Jun 14.

Address: Department of Pathology, Post Graduate Institute of Medical Education and Research; Dr. RML Hospital, New Delhi, India.

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Cytologic features, immunocytochemical findings, and DNA ploidy in four rare cases of epithelioid hemangioendothelioma involving effusions.

Cytojournal 2018 22;15:13. Epub 2018 May 22.

Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Background: Epithelioid hemangioendothelioma (EHE) involving serous effusion is extremely rare, and the diagnosis can be challenging. DNA ploidy quantitation of EHE in effusion fluids has not been previously described in the English-language literature.

Methods: Specimens of cytological diagnosed with EHE in effusion fluids between 2002 and 2009 were retrieved from the pathology files at MD Anderson Cancer Center. Read More

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May 2018
1 Read

Retropharyngeal SOL: An unusual presentation of a multifaceted entity.

Cytojournal 2018 22;15:12. Epub 2018 May 22.

Department of ENT, PGIMER, Dr. RML Hospital, New Delhi, India.

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Cytomorphological features as predictors of epidermal growth factor receptor mutation status in lung adenocarcinoma.

Cytojournal 2018 2;15:11. Epub 2018 Apr 2.

Address: Department of Cytology and Gynaecological Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Background: Epidermal growth factor receptor mutation-positive () lung adenocarcinomas are sensitive to tyrosine kinase inhibitors. Although histopathological subtype is an independent predictor of mutation status, there is a paucity of data on the cytomorphological features correlating with the mutation status. Therefore, the aim of this study was to determine whether certain cytomorphological features correlate with mutation in lung adenocarcinoma. Read More

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April 2018
1 Read

Fine needle aspiration cytology finding of a parotid mass with chondromyxoid matrix and variable epithelial cytological atypia.

Authors:
Hyun-Jung Kim

Cytojournal 2018 2;15:10. Epub 2018 Apr 2.

Address: Department of Pathology, Inje University, Sanggye -Paik Hospital, Seoul, Korea.

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A mass protruding from the pancreas featuring extensive myxoid change.

Cytojournal 2018 8;15. Epub 2018 Mar 8.

Address: Department of Laboratory Medicine, National Defense Medical College Hospital, Tokorozawa, Japan.

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March 2018
2 Reads

Cytopathologist-performed and ultrasound-guided fine needle aspiration cytology enhances diagnostic accuracy and avoids pitfalls: An overview of 20 years of personal experience with a selection of didactic cases.

Cytojournal 2018 8;15. Epub 2018 Mar 8.

Department of Pathology, Faculty of Medicine, Kocaeli University, Izmit, Kocaeli, Turkey.

Over the last few decades, fine needle aspiration cytology (FNA) has emerged as a SAFE (Simple, Accurate, Fast, Economical) diagnostic tool based on the morphologic evaluation of cells. The first and most important step in obtaining accurate results from FNA is to procure sufficient and representative material from the lesion and to appropriately transfer this material to the laboratory. Unfortunately, the most important aspect of this task occurs beyond the control of the cytopathologist, a key reason for obtaining unsatisfactory results with FNA. Read More

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March 2018
1 Read

Fine-needle aspiration of bilateral small round blue cell tumors in neck in a 65-year-old man: Significance of a wider differential.

Cytojournal 2018 16;15. Epub 2018 Feb 16.

Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.

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February 2018
1 Read

Myoepithelioma of soft tissue and diagnostic pitfall in cytology.

Cytojournal 2018 16;15. Epub 2018 Feb 16.

Department of Community Medicine, Dr. DY Patil University, Pune, Maharashtra, India.

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February 2018
1 Read

in a Papanicolaou test: An exceedingly rare finding that can be mistaken for .

Cytojournal 2018 16;15. Epub 2018 Feb 16.

Address: Dartmouth Hitchcock Medical Center, Lebanon, NH, USA.

is a zygomycetes yeast form that is very rarely detected in Papanicolaou (Pap) tests, in which it typically represents an innocuous colonizer. Its morphology closely resembles that of the better known , which can disseminate widely and cause clinically significant disease. We present a case of detected in a cervical liquid-based preparation obtained from a 38-year old healthy woman. Read More

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February 2018
1 Read

Classification of thyroid fine-needle aspiration cytology into Bethesda categories: An institutional experience and review of the literature.

Cytojournal 2018 16;15. Epub 2018 Feb 16.

Address: Department of Pathology, Salmanyia Medical Complex, Manama, Bahrain.

Background: Fine-needle aspiration cytology (FNAC) of thyroid is the initial screening test for thyroid nodules. The Bethesda system classifies thyroid FNAC into six categories. Each category is linked to a malignancy risk and has a recommended clinical management. Read More

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February 2018
1 Read

Diagnostic importance of CD56 with fine-needle aspiration cytology in suspected papillary thyroid carcinoma cases.

Cytojournal 2018 25;15. Epub 2018 Jan 25.

Address: Department of Pathology, Elazig Training and Research Hospital, Elazig, Turkey.

Background: Palpable thyroid nodules can be found in 4%-7% of the adult population; however, <5% of thyroid nodules are malignant. Immunohistochemical markers, such as CD56, can be used to make a differential diagnosis between benign and malignant lesions. To increase the accuracy of the diagnosis and distinguish the malignant aspirates from the benign ones, chose to evaluate CD56, which is normally found in benign thyroid tissue. Read More

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January 2018
11 Reads

Primary cutaneous non-Hodgkin's lymphoma, clinically mimicking a soft tissue sarcoma.

Cytojournal 2018 25;15. Epub 2018 Jan 25.

Department of Surgery, PGIMER, Dr. Ram Manohar Lohia Hospital, New Delhi, India.

Primary cutaneous B-cell lymphomas (PCBCL) are a heterogeneous group of neoplasms with distinct biology and clinical course when compared to their nodal counterparts. They usually present as violaceous, erythematous plaques, and nonulcerated nodules, which are confined to skin at the time of presentation. We present an unusual case of primary cutaneous diffuse large B-cell lymphoma, clinically mimicking a sarcoma. Read More

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January 2018
3 Reads

Fine-needle aspiration of a slowly enlarging neck mass in a 61-year-old woman: An interesting adult blue cell tumor in an unusual location.

Cytojournal 2018 25;15. Epub 2018 Jan 25.

Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, USA.

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January 2018
1 Read

Comparative evaluation of six parametric Robinson and three parametric Howell's modification of Scarf-BloomRichardson grading method on breast aspirates with histopathology: A prospective study.

Cytojournal 2017 27;14:31. Epub 2017 Dec 27.

Address: Department of Pathology, Government Medical College, Nagpur, Maharashtra, India.

Background: Fine needle aspiration cytology (FNAC) is a quick method to assess the tumor grade before its removal which will help clinicians to decide on the appropriate neo adjuvant therapy. This is essentially true in developing countries where core needle biopsy still is not used as a standard practice to sample breast carcinoma. Assessment of biological aggressiveness by cytological grading (CG) without removing the would be of immense value. Read More

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December 2017
7 Reads

Fine-needle aspiration of a right neck mass in a 10-year-old boy: Diagnostic clues and workup for tumors with small round blue cells.

Cytojournal 2017 27;14:30. Epub 2017 Dec 27.

Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at University of California, Los Angeles, CA, USA.

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December 2017
1 Read

Tubular variant of mammary adenomyoepithelioma: Diagnostic challenges and cytomorphological correlation in two cases.

Cytojournal 2017 27;14:29. Epub 2017 Dec 27.

Address: Department of Pathology, Military Hospital, Jalandhar, Punjab, India.

The authors describe the cytomorphologic features of two cases of tubular variant of adenomyoepithelioma of the breast that were first examined by fine-needle aspiration cytology (FNAC) and diagnosed as fibroadenoma. On retrospective review of the cytology, subtle features such as less cohesive epithelial clusters, intimate association of clusters of stromal cells with epithelial elements, a dominant population of plump-epithelioid naked (myoepithelial) cells, and occasional cells with intranuclear inclusions, were noted. Thus, these lesions can be diagnostically challenging and cannot be conclusively differentiated from either fibroadenoma or tubular adenoma cytologically and the pathologist may only be able to give a differential on FNAC. Read More

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December 2017
4 Reads

A case of large cell neuroendocrine carcinoma of the uterine cervix misdiagnosed as adenocarcinoma in Thinprep cytology test.

Cytojournal 2017 24;14:28. Epub 2017 Nov 24.

Address: Department of Pathology, Chonnam National University Medical School, Gwangju, Republic of Korea.

Large cell neuroendocrine carcinoma (LCNEC) of uterine cervix is a rare malignancy with aggressive behavior and poor clinical outcome even in its early stage. Few cytopathologic features of cervical LCNEC have been reported previously. A 57-year-old postmenopausal African American female, presented to the local health department with a chief complaint of heavy vaginal bleeding. Read More

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November 2017
13 Reads

Cytokeratin 20/p53 dual immunocytochemistry for improving the diagnostic accuracy of urine liquid-based cytology in the detection of urothelial neoplasm: A retrospective study.

Cytojournal 2017 24;14:27. Epub 2017 Nov 24.

Department of Urology, Inje University, Sanggye Paik Hospital, Seoul, Korea.

Backgrounds: Dual immunocytochemistry (DIC) with cytokeratin (CK) 20 and p53 in liquid-based cytology is a tool for improving the accuracy of urine cytology (UC). This study was conducted to compare the diagnostic accuracy of UC alone with that of UC combined with CK20/p53 DIC.

Methods: We retrieved urine samples collected between January 2015 and March 2016 stored in PreservCyt®solution that were from cases categorized as malignant, highly suspicious, suspicious, and atypical and that were matched with a subsequent biopsy. Read More

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November 2017
3 Reads

Cytomorphological spectrum of epididymal nodules: An institution's experience.

Cytojournal 2017 12;14:26. Epub 2017 Oct 12.

Address: Department of Pathology, Maulana Azad Medical College, New Delhi, India.

Background: Epididymal lesions are uncommon in clinical practice. Few case series has been described in the literature documenting the role of cytology in the evaluation of epididymal nodules. This study was undertaken to analyze the cytomorphology of epididymal nodules and to evaluate role of fine-needle aspiration biopsy (FNAB) in early definitive diagnosis of epididymal nodules. Read More

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October 2017
12 Reads

A case of painful ankle swelling: Cytomorphological clues and pitfalls.

Cytojournal 2017 12;14:25. Epub 2017 Oct 12.

Department of Orthopaedics, Andaman and Nicobar Island Institute of Medical Sciences, Port Blair, Andaman and Nicobar Islands, India.

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October 2017
5 Reads

Cytologic features of primary monophasic synovial sarcoma of the thyroid gland.

Cytojournal 2017 12;14:24. Epub 2017 Oct 12.

Address: Department of Pathology, Chonnam National University Medical School, Gwangju, Republic of Korea.

Synovial sarcoma (SS) is a rare soft tissue tumor, commonly arising in para-articular areas of extremities, but can also present in the head and neck area. However, primary SS of the thyroid gland is an extremely rare tumor which has been reported only five times in previous English literatures. This report presents fine needle aspiration (FNA) cytology of primary monophasic SS of the thyroid gland. Read More

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October 2017
8 Reads

Fine needle aspiration of spindle cell ductal carcinoma of the breast: A case report and the use of ancillary tests for the differential diagnosis of metaplastic carcinoma.

Cytojournal 2017 25;14:23. Epub 2017 Sep 25.

Address: Department of Hospital Pathology, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

Spindle cell ductal carcinoma (DCIS) is a recently recognized subtype of DCIS, which is associated with a very rare and unique morphology. Although the histologic features have been relatively well described in a few reports, the cytologic features have not. Even though the distinction of this lesion from usual DCIS is not crucial clinically, it should be noted that this lesion might simulate the features of metaplastic carcinoma on fine needle aspiration cytology. Read More

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September 2017
15 Reads

Significance of finding benign endometrial cells in women 40-45 versus 46 years or older on Papanicolaou tests and histologic follow-up.

Cytojournal 2017 25;14:22. Epub 2017 Sep 25.

Address: Department of Laboratory Medicine and Pathology, Mayo Clinic, Jacksonville, Florida, USA.

Background: The 2014 Bethesda System recommends reporting the finding of benign-appearing, exfoliated endometrial cells on Papanicolaou (Pap) tests in women aged 45 years and older. We aimed to determine the significance of normal endometrial cells on liquid-based Pap tests in women aged 40 years and older and to correlate this finding with clinical factors and cytologic/histologic follow-up.

Materials And Methods: We retrospectively identified all women aged 40 years and older who had benign endometrial cells (BECs) on Pap tests at our institution during a 6-year period. Read More

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September 2017
25 Reads

Perihepatic cystic mass: Zebra or horse?

Cytojournal 2017 25;14:21. Epub 2017 Sep 25.

Address: Department of Pathology and Laboratory Medicine, New York-Presbyterian Hospital, Weill Cornell Medical College, New York, USA.

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September 2017
11 Reads

Can an inadequate cervical cytology sample in ThinPrep be converted to a satisfactory sample by processing it with a SurePath preparation?

Cytojournal 2017 22;14:20. Epub 2017 Aug 22.

Department of Pathology, Akershus University Hospital, Lørenskog, Norway.

Background: The Norwegian Cervical Cancer Screening Program recommends screening every 3 years for women between 25 and 69 years of age. There is a large difference in the percentage of unsatisfactory samples between laboratories that use different brands of liquid-based cytology. We wished to examine if inadequate ThinPrep samples could be satisfactory by processing them with the SurePath protocol. Read More

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August 2017
13 Reads

Cytologic features of tubular adenoma of ampulla causing distal common bile duct stricture: A case report and review of the literature.

Cytojournal 2017 22;14:19. Epub 2017 Aug 22.

Department of Pathology, Cleveland Clinic, Cleveland, OH, USA.

Adenomas of the ampulla of Vater are distinctly rare, representing <10% of periampullary neoplasms. Very few reports of the cytologic features of ampullary adenomas are present in literature, particularly in bile duct brushing samples. A case report and review of the literature is presented. Read More

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August 2017
13 Reads

A diagnostically difficult case of a cellular pleural fluid: Morphology, immunohistochemistry, and fluorescence in situ hybridization study.

Cytojournal 2017 24;14:18. Epub 2017 Jul 24.

Address: Department Pathology, University at Buffalo-SUNY, Buffalo, NY 14203, USA.

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July 2017
12 Reads

Interobserver reproducibility of The Paris System for Reporting Urinary Cytology.

Cytojournal 2017 24;14:17. Epub 2017 Jul 24.

Department of Pathology and Laboratory Medicine and ARUP Laboratories, University of Utah, Salt Lake City, Utah, USA.

Background: The Paris System for Reporting Urinary Cytology represents a significant improvement in classification of urinary specimens. The system acknowledges the difficulty in cytologically diagnosing low-grade urothelial carcinomas and has developed categories to deal with this issue. The system uses six categories: unsatisfactory, negative for high-grade urothelial carcinoma (NHGUC), atypical urothelial cells, suspicious for high-grade urothelial carcinoma, high-grade urothelial carcinoma, other malignancies and a seventh subcategory (low-grade urothelial neoplasm). Read More

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July 2017
27 Reads

Metastatic neoplasms to the thyroid diagnosed by fine-needle aspiration/core needle biopsy: Clinicopathologic and cytomorphologic correlation.

Cytojournal 2017 20;14:16. Epub 2017 Jun 20.

Address: Department of Pathology, University of Hawaii, Honolulu, Hawaii, USA.

Background: Although thyroid fine-needle aspiration (FNA) and core needle biopsy (CNB) are commonly utilized modalities in the evaluation of thyroid nodules, metastatic tumors to the thyroid are only rarely encountered. We aspired to determine the incidence and primary origin of metastases to the thyroid at our institution and to examine their clinicopathologic and cytomorphologic features.

Materials And Methods: A search of our database was undertaken to review all thyroid FNA and/or CNB examined between January 2004 and December 2013. Read More

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June 2017
26 Reads

Metastatic prostatic stromal sarcoma: A challenging diagnosis on fine-needle aspiration with broad differential diagnosis.

Cytojournal 2017 20;14:15. Epub 2017 Jun 20.

St. John Hospital and Medical Center, Detroit, MI, USA.

Prostatic stromal sarcomas (PSS) are rare solid organ mesenchymal sarcomas. PSS may pose difficult diagnostic challenges on fine needle aspiration biopsy. We report a 48-year-old man diagnosed with metastatic high grade prostatic stromal sarcoma by a CT-scan guided fine needle aspiration (FNA) biopsy of a right lower lung lobe nodule. Read More

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June 2017
18 Reads

Myoepithelioma of soft tissue in the gluteal region: Diagnostic pitfall in cytology.

Cytojournal 2017 20;14:14. Epub 2017 Jun 20.

Address: Department of Pathology, Shri MP Shah Government Medical College, Jamnagar, Gujarat, India.

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June 2017
13 Reads

"Low-grade squamous intraepithelial lesion, cannot exclude high-grade:" TBS says "Don't Use It!" should I really stop it?

Cytojournal 2017 26;14:13. Epub 2017 May 26.

Address: Department of Pathology, NYU School of Medicine, New York, NY, USA.

Background: The Bethesda System uses a two-tiered approach in the diagnosis of cervical squamous intraepithelial lesions (SILs). Occasionally, Papanicolaou (Pap) tests with evident low-grade SIL (LSIL) also have some features suggestive but not diagnostic of high-grade SIL (HSIL). This study reviews our experience with "Low-grade Squamous Intraepithelial Lesion, Cannot Exclude High-grade" (LSIL-H) and discusses the best approach to report such Paps if the LSIL-H interpretation is abandoned. Read More

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May 2017
19 Reads

Cytological features of adenocarcinoma admixed with small cell neuroendocrine carcinoma of the uterine cervix.

Cytojournal 2017 26;14:12. Epub 2017 May 26.

Department of Oncologic Pathology, Mie University Graduate School of Medicine, Tsu, Mie 514-8507, Japan.

Adenocarcinoma admixed with neuroendocrine carcinoma of the uterine cervix is a rare malignancy with a poor prognosis, and few reports have described the cytological features of this carcinoma. To characterize the cytological features of this malignancy in cervical smears, we report a case of a 52-year-old Japanese woman with cervical adenocarcinoma admixed with small cell neuroendocrine carcinoma (SCNEC). Cytologically, there were two types of cells with different sizes. Read More

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May 2017
11 Reads

An elderly man with a solitary liver lesion.

Cytojournal 2017 26;14:11. Epub 2017 May 26.

Address: Department of Pathology and Laboratory Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA.

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May 2017
8 Reads

Cytomorphologic features distinguishing Bethesda category IV thyroid lesions from parathyroid.

Cytojournal 2017 28;14:10. Epub 2017 Apr 28.

Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY 10032, USA.

Background: Thyroid follicular cells share similar cytomorphological features with parathyroid. Without a clinical suspicion, the distinction between a thyroid neoplasm and an intrathyroidal parathyroid can be challenging. The aim of this study was to assess the distinguishing cytomorphological features of parathyroid (including intrathyroidal) and Bethesda category IV (Beth-IV) thyroid follicular lesions, which carry a 15%-30% risk of malignancy and are often followed up with surgical resection. Read More

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April 2017
13 Reads