7,539 results match your criteria Cysticercosis

[Correlation between clinical and tomographic variables in patients with neurocysticercosis. A study in a cohort of patients in Sierra Norte, Ecuador, between 2019 and 2020].

Rev Neurol 2022 06;74(12):383-391

Universidad Técnica del Norte, Imbabura, Ecuador.

Introduction: Neurocysticercosis (NCC) is the most frequent parasitic disease in the central nervous system of humans.

Objective: to establish the correlation between clinical and tomographic variables in patients with neurocysticercosis in the neurology consultation of Hospital San Vicente de Paul and Hospital IESS Ibarra, during the year 2020.

Patients And Methods: descriptive, correlational and cross-sectional research. Read More

View Article and Full-Text PDF

Knowledge, attitudes and practices related to Taenia solium cysticercosis and taeniasis in Tanzania.

BMC Infect Dis 2022 Jun 13;22(1):534. Epub 2022 Jun 13.

Center for Global Health, Department of Neurology, Technical University of Munich (TUM), Munich, Germany.

Background: Taenia solium cysticercosis/taeniasis (TSCT) is reported to be endemic in pig producing areas around the world, causing significant disease burden and economic losses.

Methods: This cross-sectional study aimed at assessing Knowledge, Attitudes and Practices (KAP) regarding TSCT in four districts, namely Mbulu, Mpwapwa, Mbinga, and Rungwe in Tanzania. Data on KAP were collected through questionnaire-based interviews and household infrastructure observations. Read More

View Article and Full-Text PDF

A chromosome-level genome assembly for the rabbit tapeworm Taenia pisiformis.

Gene 2022 Aug 6;834:146650. Epub 2022 Jun 6.

State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, Gansu Province, China; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou 225009, Jiangsu, China. Electronic address:

Taenia pisiformis is one of the most widespread gastrointestinal parasites and its larvae (cysticercosis) causes significant economic loss to rabbit industry. No efficient drug is available for this disease to date. To better understand its genomics, we assembled a 211-Mb high quality genome of T. Read More

View Article and Full-Text PDF

Larval cestodes infecting commercial fish of Alexandria coast along the Mediterranean Sea: morphology and phylogeny.

Rev Bras Parasitol Vet 2022 6;31(2):e003022. Epub 2022 Jun 6.

Zoology Department, Faculty of Science, Minia University, Minia, Egypt.

Members of the order Trypanorhyncha are cestode parasites that are frequently found infecting the muscles of several marine fish species, affecting fish health and resulting in consumers' rejection. Seventy-five specimens of marine fish were freshly caught from boat landing sites at the Alexandria coast along the Mediterranean Sea in Egypt, including two Carangids, the greater amberjack Seriola dumerili and the gulley jack Pseudocarans dentex; two Serranids, the Haifa grouper Epinephelus haifensis and the mottled grouper Mycteroperca rubra. Forty-five fish were infected; the infection was recorded as blastocysts embedded in fish flesh. Read More

View Article and Full-Text PDF

Neurocysticercosis: an update on diagnosis, treatment, and prevention.

Curr Opin Infect Dis 2022 06;35(3):246-254

Division of Infectious Diseases, Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas, USA.

Neurocysticercosis (NCC) is an important cause of neurological disease worldwide, including imported cases in nonendemic countries.

Purpose Of Review: The purpose of this review is to update information on diagnosis, management, and prevention of neurocysticercosis.

Recent Findings: WHO and Infectious Diseases Society of America/American Society of Tropical Medicine and Hygiene guidelines emphasize the importance of corticosteroids and antiparasitic drugs for viable parenchymal disease and single enhancing lesions. Read More

View Article and Full-Text PDF

A case report of cardiac cysticercosis in a returning traveller: a rare cause of myocarditis.

Simon Littlewood

Eur Heart J Case Rep 2022 May 20;6(5):ytac208. Epub 2022 May 20.

Department of Cardiology, William Harvey Hospital, Ashford, Kent TN24 0LZ, UK.

Background: A 38-year-old male of Indian origin presented via ambulance directly to the cardiac catheter lab with chest pain and electrocardiogram changes suggestive of an ST-elevation myocardial infarction. Serum troponin was recorded at >10 000 ng/L.

Case Summary: Angiogram revealed normal coronary arteries. Read More

View Article and Full-Text PDF

taeniasis/cysticercosis in Guatemala: a prevalent public health problem?

Pathog Glob Health 2022 Jun 3:1-9. Epub 2022 Jun 3.

Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Ciudad de México, México.

In Guatemala, neurocysticercosis (NCC) was first recognized in 1940; since then, cases of NCC have been reported in all Guatemalan departments. However, epidemiological studies on infections are scarce and most information remains unpublished. This study aims to provide evidence of infections as a public health problem in Guatemala. Read More

View Article and Full-Text PDF

Porcine model of neurocysticercosis by intracarotid injection of Taenia solium oncospheres: Dose assessment, infection outcomes and serological responses.

PLoS Negl Trop Dis 2022 06 2;16(6):e0010449. Epub 2022 Jun 2.

Center for Global Health, Universidad Peruana Cayetano Heredia, Lima, Peru.

Background: Neurocysticercosis (NCC) is the infection of the human central nervous system (CNS) by Taenia solium larvae that cause significant neurological morbidity. Studies on NCC pathophysiology, host-parasite interactions or therapeutic agents are limited by the lack of suitable animal models. We have previously reported that carotid injection of activated T. Read More

View Article and Full-Text PDF

The Genomes of Two Strains of the Animal Model for the Study of Human Cysticercosis.

Front Cell Infect Microbiol 2022 10;12:876839. Epub 2022 May 10.

Biomedical Research Institute, Universidad Nacional Autónoma de México, CDMX, Mexico.

Human cysticercosis by is the major cause of neurological illness in countries of Africa, Southeast Asia, and the Americas. Publication of four cestode genomes (, , and ) in the last decade, marked the advent of novel approaches on the study of the host-parasite molecular crosstalk for cestode parasites of importance for human and animal health. is another cestode parasite, closely related to , which has been used in numerous studies as an animal model for human cysticercosis. Read More

View Article and Full-Text PDF

A recombinant monoclonal-based Taenia antigen assay that reflects disease activity in extra-parenchymal neurocysticercosis.

PLoS Negl Trop Dis 2022 05 26;16(5):e0010442. Epub 2022 May 26.

Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, United States of America.

Background: Antigen tests for diagnosis and disease monitoring in some types of neurocysticercosis (NCC) are useful but access to testing has been limited by availability of proprietary reagents and/or kits.

Methods/principal Findings: Three previously identified IgM-secreting hybridomas whose IgM products demonstrated specificity to Taenia solium underwent variable heavy and light chain sequencing and isotype conversion to mouse IgG. Screening of these recombinantly expressed IgG anti-Ts hybridomas, identified one (TsG10) with the highest affinity to crude Taenia antigen. Read More

View Article and Full-Text PDF

Sub-lineages of Taenia solium Asian Genotype Recorded in North India.

Acta Parasitol 2022 May 26. Epub 2022 May 26.

Department of Veterinary Parasitology, College of Veterinary Sciences, Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar, Haryana, 125001, India.

Purpose: Porcine cysticercosis is a neglected zoonotic disease of significant veterinary and medical importance owing to its economic impact and public health significance. The present study aimed at genetic characterization of Taenia solium metacestodes in slaughtered pigs of Haryana (North India).

Methods: A total of 213 (160 and 53 from Chandigarh and Hisar, respectively) slaughtered pigs intended for human consumption were screened for the presence of T. Read More

View Article and Full-Text PDF

Urine 1H-NMR Metabolomics to Discriminate Neurocysticercosis Patients from Healthy Controls: An Exploratory Study.

Am J Trop Med Hyg 2022 May 23. Epub 2022 May 23.

The diagnosis of neurocysticercosis (NCC) is principally based on neuroimaging (magnetic resonance imaging or computed tomography), instrumentation that is scarcely available in the rural regions where Taenia solium transmission, primarily occurs due to poor sanitation conditions. Immunological assays for antigen or antibody detection complement the neuroimaging approach. However, no field-applicable assays to diagnose viable NCC or to guide the referral of cases for neuroimaging or for appropriate management are available. Read More

View Article and Full-Text PDF

Analysis of immune response in BALB/c mice immunized with recombinant plasmids pMZ-X3-Ts14-3-3.3 and pMZ-X3-sp-Ts14-3-3.3 of Taenia solium.

Acta Trop 2022 Aug 17;232:106517. Epub 2022 May 17.

Department of Parasitology, Zunyi Medical University, Zunyi 563000, China. Electronic address:

There is a lack of vaccine against human cysticercosis, thus making a huge population at the risk of infection. In this study, we chose a novel potential antigen molecule Taenia solium 14-3-3.3 (Ts14-3-3. Read More

View Article and Full-Text PDF

CystiHuman: A model of human neurocysticercosis.

PLoS Comput Biol 2022 05 19;18(5):e1010118. Epub 2022 May 19.

Center for Global Health Tumbes, Universidad Peruana Cayetano Heredia, Lima, Peru.

Introduction: The Taenia solium tapeworm is responsible for cysticercosis, a neglected tropical disease presenting as larvae in the body of a host following taenia egg ingestion. Neurocysticercosis (NCC), the name of the disease when it affects the human central nervous system, is a major cause of epilepsy in developing countries, and can also cause intracranial hypertension, hydrocephalus and death. Simulation models can help identify the most cost-effective interventions before their implementation. Read More

View Article and Full-Text PDF

Endemic Thoracic Infections in Sub-Saharan Africa.

Radiol Clin North Am 2022 May;60(3):461-479

Alliar Group, Rua Ernesto Nazaré, 389 - Alto de Pinheiros, São Paulo, São Paulo 05462-000, Brazil.

Although many of the thoracic infections endemic to Africa are also present around the world, this article focuses on entities that are emerging or disproportionately affect populations living in sub-Saharan Africa. Important emerging or reemerging viral and bacterial diseases that commonly affect the lung include dengue fever, plague, leptospirosis, and rickettsioses. Most parasitic infections endemic to Africa can also manifest within the thorax, including malaria, amebiasis, hydatid disease, schistosomiasis, paragonimiasis, ascariasis, strongyloidiasis and cysticercosis. Read More

View Article and Full-Text PDF

Endemic Thoracic Infections in Latin America and the Caribbean.

Radiol Clin North Am 2022 May;60(3):429-443

The University of Texas Health Science Center at San Antonio.

Infectious diseases, including parasitic diseases, which are commonly associated with poverty and poor sanitation, continue to cause significant morbidity, disability, and mortality in Latin America and the Caribbean region. This article reviews the epidemiology, pathophysiology, and cardiothoracic imaging manifestation of several communicable diseases endemic to this region. Read More

View Article and Full-Text PDF

In vitro metabolic stress induced by nitazoxanide and flubendazole combination in Taenia crassiceps cysticerci.

Exp Parasitol 2022 Jul 5;238:108265. Epub 2022 May 5.

Laboratory of Studies of the Host-parasite Relationship, Tropical Pathology and Public Health Institute, Federal University of Goias, Brazil. Electronic address:

Taenia crassiceps is often used as experimental model for T. solium cysticercosis studies. Currently cysticercosis antiparasitic treatment is based on albendazole and praziquantel which may present side effects and parasitic resistance. Read More

View Article and Full-Text PDF

[Travel vaccines: what is in the pipeline?]

Rev Med Suisse 2022 May;18(780):890-893

Policlinique de médecine tropicale, voyages et vaccinations, Centre de médecine générale et santé publique, Unisanté, 1011 Lausanne.

While no vaccine is on the horizon to prevent traveler's diarrhea, progress has been made in the field of malaria and dengue fever. In both cases, the objective is not primarily the prevention among travelers but rather the reduction of morbidity and mortality in populations living in endemic areas. The immune mechanisms protecting against parasitosis are not well understood, which further complicates vaccine development. Read More

View Article and Full-Text PDF

Knowledge, attitude, and practices of the community and meat industry workers towards Taenia saginata taeniosis and bovine cysticercosis in and around Jimma and Ambo towns of Ethiopia.

Prev Vet Med 2022 Jul 19;204:105653. Epub 2022 Apr 19.

Department of Translational Physiology, Infectiology, and Public Health, Laboratory of Foodborne Parasitic Zoonoses, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium.

Taenia saginata taeniosis and bovine cysticercosis are prevalent in Ethiopia, however, data on the knowledge/attitude, and practice (KAP) of the community and meat industry workers in this regard is scarce. The present study aimed to investigate the KAP of the community and meat industry workers about T. saginata taeniosis/cysticercosis in Jimma and Ambo towns of Ethiopia. Read More

View Article and Full-Text PDF

Quality of life in patients with symptomatic epilepsy due to neurocysticercosis.

Epilepsy Behav 2022 06 25;131(Pt A):108668. Epub 2022 Apr 25.

Cysticercosis Unit, Instituto Nacional de Ciencias Neurológicas, Lima, Peru; Center for Global Health, Universidad Peruana Cayetano Heredia, Lima, Peru.

Background: Neurocysticercosis (NCC) is a common cause of late-onset epilepsy worldwide, but there is still minimal information regarding its impact on a patient's quality of life. This study evaluated quality of life in a series of patients with epilepsy secondary to NCC using the QOLIE (Quality of Life in Epilepsy)-31 questionnaire.

Methodology: This cross-sectional study included 155 Peruvian patients between 16 and 70 years of age with epilepsy due to viable intraparenchymal NCC, who enrolled in two trials of anti-parasitic treatment during the period 2006-2011. Read More

View Article and Full-Text PDF

Movements of free-range pigs in rural communities in Zambia: an explorative study towards future ring interventions for the control of Taenia solium.

Parasit Vectors 2022 Apr 27;15(1):150. Epub 2022 Apr 27.

Laboratory of Foodborne Parasitic Zoonoses, Ghent University, Salisburylaan 133, 9820, Merelbeke, Belgium.

Background: Taenia solium typically affects resource-poor communities where pigs are allowed to roam freely, and sanitation and hygiene levels are suboptimal. Sustainable, long-term strategies are urgently needed to control the disease. Geographically targeted interventions, i. Read More

View Article and Full-Text PDF

Case 305.

Radiology 2022 05;303(2):477-479

From the Department of Diagnostic and Therapeutic Services, Radiology Unit, IRCCS ISMETT (Mediterranean Institute for Transplantation and Advanced Specialized Therapies), Via Tricomi 5, Palermo 90127, Sicily, Italy.

History: A 27-year-old man was admitted to the emergency department with fever and thoracic pain. In the previous 6 months, the patient lost a substantial amount of weight (12 kg). His family history was negative for cardiac disease. Read More

View Article and Full-Text PDF

Stakeholders' Knowledge, Attitude, and Perceptions on the Control of in Kamuli and Hoima Districts, Uganda.

Front Vet Sci 2022 7;9:833721. Epub 2022 Apr 7.

Animal and Human Health Program, International Livestock Research Institute, Nairobi, Kenya.

is a zoonotic parasite causing three diseases: Taeniasis and cysticercosis in humans and porcine cysticercosis in pigs. Although biomedically, the transmission of the parasite can be easily interrupted at six points along the life cycle, the contextual factors that may influence the adoption of these control strategies in Uganda remain unclear. This study assessed the stakeholders' knowledge, attitudes, and perceptions relating to the six control strategies for infections in Kamuli and Hoima districts, Uganda. Read More

View Article and Full-Text PDF

Comparative Efficacy and Safety of Lacosamide and Oxcarbazepine for Seizure Control in Children with Newly Diagnosed Solitary Neurocysticercosis.

J Trop Pediatr 2022 04;68(3)

Department of Radiodiagnosis and Imaging, All India Institute of Medical Sciences, Rishikesh 249203, India.

Background: In newly diagnosed neurocysticercosis (NCC) with seizures, the choice of anti-seizure medication (ASM) seems to be arbitrary due to a lack of comparative studies. Although oxcarbazepine (OXC) is often considered efficacious for focal seizures in NCC, due to adverse effects, newer ASMs like levetiracetam (LCM) and lacosamide are also being explored.

Methods: This study was performed by case record review of children with newly diagnosed solitary viable parenchymal NCC aged 4-18years who received lacosamide and OXC at least for 12 weeks between August 2019 and April 2021, from a prospective registry of a tertiary care teaching hospital in north India. Read More

View Article and Full-Text PDF

Seroprevalence and Associated Risk Factors of Trichinellosis and Cysticercosis in Indigenous Pigs in Hoa Binh Province, Vietnam.

Trop Med Infect Dis 2022 Apr 7;7(4). Epub 2022 Apr 7.

International Livestock Research Institute, Hanoi 100000, Vietnam.

Trichinellosis and cysticercosis remain challenges to human health and animal productivity worldwide, especially in developing countries. While information on the occurrence of both diseases is infrequent, they are endemic in parts of Vietnam and mainly related to indigenous pigs kept by ethnic minorities. This study aimed to determine the seroprevalence and risk factors of both diseases in indigenous pigs and explore the perception and awareness of both human and pig trichinellosis and cysticercosis of pig farmers. Read More

View Article and Full-Text PDF

Prevalence and genetic variance of Taenia hydatigena in goats and sheep from northern Ghana: Preliminary data on a globally neglected livestock parasite.

Vet Parasitol Reg Stud Reports 2022 05 19;30:100711. Epub 2022 Feb 19.

University of Hohenheim, Institute of Biology, Parasitology Unit, Emil-Wolff-Str. 34, 70599 Stuttgart, Germany.

Cysticercosis caused by the larval stages of Taenia hydatigena has a significant global impact on livestock production, particularly of goats and sheep. Despite this, global data on prevalence and genetic variance of this parasite are still scarce. In Ghana, as in most African countries, numerous anecdotal observations agree that it is widespread and frequent. Read More

View Article and Full-Text PDF

Prevalence and factors associated with human Taenia solium taeniosis and cysticercosis in twelve remote villages of Ranomafana rainforest, Madagascar.

PLoS Negl Trop Dis 2022 04 11;16(4):e0010265. Epub 2022 Apr 11.

Institut Pasteur de Madagascar, Immunology of Infectious Diseases Unit, Antananarivo, Madagascar.

Background: Infections with the tapeworm Taenia solium (taeniosis and cysticercosis) are Neglected Tropical Diseases (NTD) highly endemic in Madagascar. These infections are however underdiagnosed, underreported and their burden at the community level remains unknown especially in rural remote settings. This study aims at assessing the prevalence of T. Read More

View Article and Full-Text PDF

Epidemiological status of bovine cysticercosis and human taeniasis in Eastern Ethiopia.

Parasite Epidemiol Control 2022 May 2;17:e00248. Epub 2022 Apr 2.

Woldia University, Department of Veterinary Medicine, Merssa, Ethiopia.

Bovine cysticercosis and human taeniasis are among the leading cause of economic loss in Ethiopia due to organ condemnation and treatment costs. A cross-sectional study was conducted from September 2017 to July 2018 on randomly selected carcasses from Jigjiga, Babile and Dire Dawa town municipal abattoirs to estimate the prevalence of bovine cysticercosis. Besides, a questionnaire was administered to the human population of these towns to understand risk of human taeniasis. Read More

View Article and Full-Text PDF

Distribution of bovine cysticercosis prevalence in the southeastern districts of Botswana from 2015 to 2016.

Vet World 2022 Feb 17;15(2):368-373. Epub 2022 Feb 17.

Department of Veterinary Sciences, Faculty of Animal and Veterinary Sciences, Botswana University of Agriculture and Natural Resources, Private Bag 0027, Gaborone, Botswana.

Background And Aim: Bovine cysticercosis is defined as a foodborne parasitic zoonotic disease of cattle caused by the larval stage of the human tapeworm . In Botswana, bovine cysticercosis has inflicted major economic consequences on the beef industry due to downgrading, condemnation, or treatment of infected carcasses. Thus, in this study, we aim to (1) estimate the prevalence of bovine cysticercosis in Botswana's southeastern districts, (2) describe the distribution of bovine cysticercosis through geospatial mapping, and (3) investigate the effect of seasonality on bovine cysticercosis occurrence. Read More

View Article and Full-Text PDF
February 2022