6,826 results match your criteria Cysticercosis


[Calcified Cysticercosis and Differential Diagnosis of Intracranial, Cutaneous and Subcutanoeus Calcifications.]

Rofo 2019 Feb 14. Epub 2019 Feb 14.

Department for Diagnostic and Interventional Radiology, University-Hospital Tübingen.

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http://dx.doi.org/10.1055/a-0846-7527DOI Listing
February 2019

A Classic Neurocysticercosis Case with an Unusual Complication.

Eur J Case Rep Intern Med 2018 31;5(1):000762. Epub 2018 Jan 31.

Infectious Diseases Department, Hospital de Santa Maria, Lisbon, Portugal.

Cysticercosis is triggered by infection with the larval form of the tapeworm . The usual sites for the development of cyscticerci are the central nervous system (neurocysticercosis - NCC), subcutaneous tissue, skeletal muscle, heart muscle, and the eye. Ocular cysticercosis is caused by the growth of the larvae within ocular tissues. Read More

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http://dx.doi.org/10.12890/2017_000762DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346944PMC
January 2018

A quantitative risk assessment for human Taenia solium exposure from home slaughtered pigs in European countries.

Parasit Vectors 2019 Feb 12;12(1):82. Epub 2019 Feb 12.

National Institute for Public Health and the Environment (RIVM), Center for Infectious Disease Control, P.O. Box 1, 3720, BA, Bilthoven, The Netherlands.

Background: Taenia solium, a zoonotic tapeworm, is responsible for about a third of all preventable epilepsy human cases in endemic regions. In Europe, adequate biosecurity of pig housing and meat inspection practices have decreased the incidence of T. solium taeniosis and cysticercosis. Read More

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http://dx.doi.org/10.1186/s13071-019-3320-3DOI Listing
February 2019

Fine Needle Aspiration Cytology of Cysticercosis: A Study of 30 Cases.

J Cytol 2019 Jan-Mar;36(1):18-21

Department of Pathology, Govt. Medical College, Srinagar, Jammu and Kashmir, India.

Cysticercosis is a systemic parasitic disease caused by larval stage of Taenia solium. It is the most common parasitic disease worldwide. It is potentially a dangerous systemic disease with variable clinical manifestations. Read More

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http://dx.doi.org/10.4103/JOC.JOC_77_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343397PMC
February 2019
1 Read

Pharmacokinetics, Safety, and Tolerability of Oxfendazole in Healthy Volunteers: a Randomized, Placebo-Controlled First-in-Human Single-Dose Escalation Study.

Antimicrob Agents Chemother 2019 02 11. Epub 2019 Feb 11.

Division of Infectious Diseases, Carver College of Medicine, University of Iowa, USA.

Cysticercosis is a parasitic disease that frequently involves the human central nervous system (CNS) and current treatment options are limited. Oxfendazole, a veterinary medicine belonging to the benzimidazole family of anthelmintic drugs, has demonstrated substantial activity against the tissue stages of and has potential to be developed as an effective therapy for neurocysticercosis. To accelerate the transition of oxfendazole from veterinary to human use, the pharmacokinetics, safety and tolerability of oxfendazole were evaluated in healthy volunteers in this Phase 1 first-in-human (FIH) study. Read More

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http://dx.doi.org/10.1128/AAC.02255-18DOI Listing
February 2019
1 Read

Ultrasonographic features of mesenteric cysticercosis in a domestic rabbit (Oryctolagus cuniculus).

Vet Radiol Ultrasound 2019 Feb 10. Epub 2019 Feb 10.

Small Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Veterinary Teaching Hospital, Fort Collins, CO 80523.

A 5-year-old, 0.92-kg (2-lb), spayed female Dwarf Hotot rabbit was evaluated for a 1-day duration of lethargy and anorexia. Survey radiographs revealed evidence of gastrointestinal stasis. Read More

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http://dx.doi.org/10.1111/vru.12719DOI Listing
February 2019
1 Read

Disseminated cysticercosis in an immunocompetent individual.

Ann Afr Med 2019 Jan-Mar;18(1):51-53

Department of General Medicine, Saveetha Medical College, Saveetha University, Chennai, Tamil Nadu, India.

Cysticercosis is a major public health problem, particularly in developing countries. It is caused by the larvae of the cestode Taenia solium (pork tapeworm). It usually presents as a solitary lesion in the muscle or brain (neurocysticercosis). Read More

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http://dx.doi.org/10.4103/aam.aam_76_17DOI Listing
February 2019
1 Read

Albendazole sulfoxide plasma levels and efficacy of antiparasitic treatment in patients with parenchymal neurocysticercosis.

Clin Infect Dis 2019 Feb 2. Epub 2019 Feb 2.

School of Public Health and Administration (GA, AGL), Department of Microbiology, School of Sciences and Center for Global Health (JAB, HHG), Universidad Peruana Cayetano Heredia, Lima, Peru.

Background: Albendazole is the drug of choice for the treatment of parenchymal neurocysticercosis, although its efficacy is suboptimal. Plasma levels of albendazole sulfoxide (ASOX), the active metabolite of albendazole, are highly variable among patients. We hypothesized that high ASOX plasma levels during albendazole therapy may be associated with an increased antiparasitic efficacy. Read More

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http://dx.doi.org/10.1093/cid/ciz085DOI Listing
February 2019
1 Read

Neurocysticerosis: An Individualized Approach.

Infect Dis Clin North Am 2019 Mar;33(1):153-168

Department of Medicine, Division of Infectious Disease, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA. Electronic address:

Neurocysticercosis is an infection of the central nervous system by the larval stage of the pork tapeworm Taenia solium. The combination of modern diagnostic tests, use of antiparasitic drugs, improved anti-inflammatory treatments, and minimally invasive neurosurgery has improved outcomes in patients with neurocysticercosis. This parasitic infection is complex in both the clinical presentation and the treatment approach, which depends on the number of cysts, location in the brain, stage of degeneration, and host inflammatory response. Read More

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http://dx.doi.org/10.1016/j.idc.2018.10.007DOI Listing
March 2019
1 Read

Three unusual cases of parasites in eye.

Indian J Pathol Microbiol 2019 Jan-Mar;62(1):159-162

Department of Pathology, Dhruv Pathology and Molecular Diagnostic Lab, Nagpur, Maharashtra, India.

A 17-year-old male patient presented with cellulitis and mass in the eye noticed approximately 3 months back. The mass was about 1 cm in size and situated at the limbus. All preoperative routine investigations were normal. Read More

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http://dx.doi.org/10.4103/IJPM.IJPM_247_18DOI Listing
February 2019
2 Reads

Evaluation of cross-reactivity to Taenia hydatigena and Echinococcus granulosus in the enzyme-linked immunoelectrotransfer blot assay for the diagnosis of porcine cysticercosis.

Parasit Vectors 2019 Jan 24;12(1):57. Epub 2019 Jan 24.

Center for Global Health Tumbes, Universidad Peruana Cayetano Heredia, Tumbes, Peru.

Background: Taenia solium is an important zoonotic parasite that infects humans as definitive host (taeniasis) and pigs as intermediate host (cysticercosis). Serological diagnosis of porcine cysticercosis is limited to antigen detection using ELISA, which is known to cross-react with other Taenia species, and antibody detection using the lentil-lectin glycoprotein enzyme-linked immunoelectrotransfer blot (LLGP EITB), which has not been adequately evaluated for cross-reactivity to other parasites. Field studies suggest that the GP50 diagnostic band of the LLGP EITB may cross-react to Taenia hydatigena, a common non-zoonotic parasitic infection of pigs. Read More

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https://parasitesandvectors.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s13071-018-3279-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346519PMC
January 2019
3 Reads
3.430 Impact Factor

Estimating the association between being seropositive for cysticercosis and the prevalence of epilepsy and severe chronic headaches in 60 villages of rural Burkina Faso.

PLoS Negl Trop Dis 2019 01 24;13(1):e0007101. Epub 2019 Jan 24.

Centre Hospitalier Universitaire Souro SANOU, Bobo-Dioulasso, Burkina Faso.

Background: Individuals diagnosed with neurocysticercosis often present with epilepsy and sometimes with progressively worsening severe chronic headaches (WSCH). While cross-sectional associations between seropositivity to cysticercal antigens and epilepsy have been reported, few large scale studies have been conducted in West Africa and none have measured the association between seropositivity to cysticercal antigens and headaches. This study aimed at filling these knowledge gaps by estimating the strength of the cross-sectional association between seropositivity to cysticercal antigens and the prevalence of epilepsy and WSCH in 60 villages of Burkina Faso, West Africa. Read More

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http://dx.doi.org/10.1371/journal.pntd.0007101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345432PMC
January 2019
2 Reads

First Molecular Identification of Taenia hydatigena in Wild Ungulates in Poland.

Ecohealth 2019 Jan 23. Epub 2019 Jan 23.

W. Stefański Institute of Parasitology PAS, Twarda 51/55, 00-818, Warsaw, Poland.

The article examines the presence of metacestodes on the liver capsule in two wild boars and on the liver capsule and mediastinum in moose. Cysticerci were identified as Taenia hydatigena metacestodes by morphological features-size and shape of rostellar hooks and molecular analysis of the partial sequences of cytochrome c oxidase subunit 1 gene. Molecular analysis revealed similarities between the metacestodes isolated from the wild mammals in the present study to T. Read More

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http://dx.doi.org/10.1007/s10393-019-01392-9DOI Listing
January 2019

control in Zambia: The potholed road to success.

Parasite Epidemiol Control 2019 Feb 19;4:e00082. Epub 2018 Dec 19.

Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.

The taeniosis/cysticercosis neglected zoonotic disease complex is caused by , and is associated with significant economic and public health impacts. This paper reviews the current knowledge on in Zambia and the control strategies already studied, covering almost 20 years of research, and explores the way forward. Studies on occurrence of porcine cysticercosis indicated very high prevalences, ranging from 15 to 34% based on detection of circulating antigens, and of 46% to 68% based on full carcass dissection in slaughter age pigs. Read More

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http://dx.doi.org/10.1016/j.parepi.2018.e00082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324015PMC
February 2019
2 Reads

Spatiotemporal distribution and economic loss associated with bovine cysticercosis and human taeniasis in Ethiopia.

Parasite Epidemiol Control 2019 Feb 17;4:e00078. Epub 2018 Nov 17.

College of Veterinary Medicine, Haramaya University, Po. Box. 138, Dire Dawa, Ethiopia.

A metacestode stage (bovine cysticercosis) and adult stage , accounted for zoonotic and economic losses from organ contamination and treatment cost. The objective of this paper is to assess the spatiotemporal distribution and economic loss from bovine cysticercosis and human taeniasis with treatment approach in different parts of Ethiopia. All available published research articles from Ethiopia on the disease were collected. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S24056731183003
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http://dx.doi.org/10.1016/j.parepi.2018.e00078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324008PMC
February 2019
3 Reads

The impact of imperfect screening tools on measuring the prevalence of epilepsy and headaches in Burkina Faso.

PLoS Negl Trop Dis 2019 01 17;13(1):e0007109. Epub 2019 Jan 17.

Department of Biostatistics and Epidemiology, College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America.

Background: Epilepsy and progressively worsening severe chronic headaches (WSCH) are the two most common clinical manifestations of neurocysticercosis, a form of cysticercosis. Most community-based studies in sub-Saharan Africa (SSA) use a two-step approach (questionnaire and confirmation) to estimate the prevalence of these neurological disorders and neurocysticercosis. Few validate the questionnaire in the field or account for the imperfect nature of the screening questionnaire and the fact that only those who screen positive have the opportunity to be confirmed. Read More

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http://dx.doi.org/10.1371/journal.pntd.0007109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353216PMC
January 2019
3 Reads

Performance of a Sandwich Antigen-Detection ELISA for the Diagnosis of Porcine Cysticercosis.

Am J Trop Med Hyg 2019 Jan 14. Epub 2019 Jan 14.

School of Veterinary Medicine, Universidad Nacional Mayor de San Marcos, Lima, Peru.

The pig is the natural intermediate host of , a parasite causing significant burden of disease in both humans and pigs. Porcine cysticercosis is traditionally detected via tongue palpation and slaughterhouse meat inspection, both with limited sensitivity. Serum antibody detection has a better performance; however, it does not discriminate past from present infection. Read More

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http://www.ajtmh.org/content/journals/10.4269/ajtmh.18-0697
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http://dx.doi.org/10.4269/ajtmh.18-0697DOI Listing
January 2019
4 Reads
2.699 Impact Factor

Letter in response to Del Brutto, axonal swelling and spheroids in Taenia solium neurocysticercosis.

Brain Pathol 2019 Jan 13. Epub 2019 Jan 13.

Infectious Diseases Laboratory Research-LID, Faculty of Science and Philosophy, Alberto Cazorla Talleri, Universidad Peruana Cayetano Heredia, Lima, Perú.

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http://dx.doi.org/10.1111/bpa.12700DOI Listing
January 2019
3 Reads

Molecular characterization of the Taenia solium Tso31 antigen and homologous of other Taenia species from Peru.

Parasitol Res 2019 Jan 9. Epub 2019 Jan 9.

School of Veterinary Medicine, Universidad Nacional Mayor de San Marcos, Av. Circunvalación Cdra. 28, San Borja, Lima, Peru.

Several studies have been performed to determine specific antigens for the diagnosis of tapeworms. One of these antigens is Tso31, which is used to differentiate Taenia solium and Taenia saginata in human feces. The aim of the present work was the molecular characterization of this protein in different tapeworm specimens collected in Peru: T. Read More

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http://dx.doi.org/10.1007/s00436-018-06195-5DOI Listing
January 2019
2.327 Impact Factor

Cytological diagnosis of cysticercosis: Role of FNAC with On-Site evaluation.

IDCases 2019 11;15:e00477. Epub 2018 Dec 11.

Department of Pathology, Seth GSMC & KEMH, Parel, Mumbai, Maharashtra, 400012, India.

Cysticercosis is a zoonotic disease, caused by the larval form of pork tapeworm . This disease is a public health problem in a country such as India, but its incidence is likely underestimated. With the advent of fine needle aspiration cytology (FNAC) with rapid on-site evaluation (ROSE), early detection of this disease is possible, especially when the lesion is in anatomically approachable superficial locations. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22142509183017
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http://dx.doi.org/10.1016/j.idcr.2018.e00477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305697PMC
December 2018
1 Read

A Case Report of Isolated Cysticercosis of Biceps Muscle.

J Orthop Case Rep 2018 May-Jun;8(3):89-91

Department of Pathology, Kasturba Medical College, Mangalore. Manipal Academy Of Higher Education Manipal, Karnataka, India.

Introduction: Cysticercosis is more commonly seen in developing countries like India caused by larval stage of Taenia solium. Neurocysticercosis is more commonly seen than isolated muscle involvement. There are very few sporadic cases of isolated biceps muscle involvement, but most of them are managed medically. Read More

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http://dx.doi.org/10.13107/jocr.2250-0685.1126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298702PMC
December 2018
1 Read

Analysis of Immune Responses in Mice Orally Immunized with Recombinant pMG36e-SP-TSOL18/ and pMG36e-TSOL18/ Vaccines of .

J Immunol Res 2018 18;2018:9262631. Epub 2018 Nov 18.

Department of Parasitology, School of Basic Medical Sciences, Zunyi Medical University, Zunyi, China.

Cysticercosis is a cosmopolitan zoonotic parasitic disease infected by larval of (). Several drugs for the treatment of cysticercosis, such as praziquantel, albendazole, and mebendazole, have certain toxicity and side effects. Considering that there is no vaccine available, we studied a new vaccine for cysticercosis in this study. Read More

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http://dx.doi.org/10.1155/2018/9262631DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276433PMC
November 2018
4 Reads

General contextual effects on neglected tropical disease risk in rural Kenya.

PLoS Negl Trop Dis 2018 12 21;12(12):e0007016. Epub 2018 Dec 21.

International Livestock Research Institute, Nairobi, Kenya.

The neglected tropical diseases (NTDs) are characterized by their tendency to cluster within groups of people, typically the poorest and most marginalized. Despite this, measures of clustering, such as within-group correlation or between-group heterogeneity, are rarely reported from community-based studies of NTD risk. We describe a general contextual analysis that uses multi-level models to partition and quantify variation in individual NTD risk at multiple grouping levels in rural Kenya. Read More

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http://dx.plos.org/10.1371/journal.pntd.0007016
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http://dx.doi.org/10.1371/journal.pntd.0007016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342328PMC
December 2018
6 Reads

Epidemiology of taeniosis, cysticercosis and trichinellosis in Iran: A systematic review.

Zoonoses Public Health 2019 Feb 21;66(1):140-154. Epub 2018 Dec 21.

Department of Community and Public Health, Technical University of Kenya, Nairobi, Kenya.

Background: The aim of this review was to establish the current epidemiology of taeniosis, cysticercosis and trichinellosis among humans and animals in Iran by carrying out a comprehensive assessment of published articles reporting on these foodborne zoonotic diseases across the country.

Methods: The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline was used in the search for relevant published articles reporting on cysticercosis, taeniosis and trichinellosis in Iran using a number of appropriate key words. The search was conducted through PubMed, Web of Science, Google Scholar, SpringerLink, SCOPUS, WHOLIS, FAO and CDC. Read More

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http://dx.doi.org/10.1111/zph.12547DOI Listing
February 2019
2 Reads
2.065 Impact Factor

[Changes of brain CT imaging of cerebral cysticercosis patients during the period of anti-cysticercus chemotherapy].

Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi 2018 Oct;30(5):523-526

Shandong Institute of Parasitic Diseases, Shandong Academy of Medical Sciences, The Third Affiliated Hospital of Shandong Academy of Medical Sciences, Jining 272033, China.

Objective: To investigate the changes of brain CT imaging in patients with cerebral cysticercosis during the period of anti-cysticercus chemotherapy.

Methods: A total of 380 inpatients that were conformed to the practical diagnostic criteria of cerebral cysticercosis were enrolled in this study in the Third Affiliated Hospital of Shandong Academy of Medical Sciences from May 2010 to May 2015. All the patients were given anti-cysticercus chemotherapy (albendazole and praziquantel). Read More

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http://dx.doi.org/10.16250/j.32.1374.2018016DOI Listing
October 2018
8 Reads

Clustering of Necropsy-Confirmed Porcine Cysticercosis Surrounding Tapeworm Carriers in Peru.

Am J Trop Med Hyg 2019 Feb;100(2):314-322

Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.

The pork tapeworm, , is among the leading causes of preventable epilepsy in the world and is common in rural areas of developing countries where sanitation is limited and pigs have access to human feces. Prior studies in rural villages of Peru have observed clusters of cysticercosis among pigs that live near human tapeworm carriers. Such spatial analyses, however, have been limited by incomplete participation and substandard diagnostic tests. Read More

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http://www.ajtmh.org/content/journals/10.4269/ajtmh.18-0296
Publisher Site
http://dx.doi.org/10.4269/ajtmh.18-0296DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367604PMC
February 2019
3 Reads
2.699 Impact Factor

Epidemiology of Taenia saginata taeniosis/cysticercosis in the Russian Federation.

Parasit Vectors 2018 Dec 14;11(1):636. Epub 2018 Dec 14.

Section of Epidemiology, Vetsuisse Faculty, University of Zurich, 8057, Zurich, Switzerland.

Background: Russia is traditionally an endemic area for Taenia saginata infection, where a programme for the prevention of infection has been implemented for sixty years. This paper aims, therefore, to review the recent epidemiology data of Taenia saginata infection in the Russian Federation.

Methods: We undertook a systematic review of published and grey literature, and official data for information on the incidence, prevalence and distribution of Taenia saginata taeniosis and cysticercosis in the Russian Federation between 1st January 1991 and 31st December 2017. Read More

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http://dx.doi.org/10.1186/s13071-018-3236-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293649PMC
December 2018

Solitary myocysticercosis of masseter muscle: A rare presentation.

Natl J Maxillofac Surg 2018 Jul-Dec;9(2):229-231

Department of Oral and Maxillofacial Surgery, Faculty of Dental Sciences, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.

Cysticercosis in human is caused by larva of cyclophyllid cestode named . Worm infestation is quite common in developing countries due to poor sanitation, habit of open defection. This condition primarily involves central nervous system. Read More

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http://www.njms.in/text.asp?2018/9/2/229/245340
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http://dx.doi.org/10.4103/njms.NJMS_18_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251284PMC
December 2018
2 Reads

The status and health burden of neurocysticercosis in Mbulu district, northern Tanzania.

BMC Res Notes 2018 Dec 13;11(1):890. Epub 2018 Dec 13.

Department of Zoology and Wildlife Conservation, University of Dar es Salaam, P.O. Box 35064, Dar es Salaam, Tanzania.

Objective: The objective of this study was to assess the extent and health burden of neurocysticercosis in the general community of the Mbulu district, northern Tanzania. About 1051 randomly select participants were screened for human cysticercosis. The Cysticercus Western Blot IgG and Computed Tomography scan were used to detect infection by cysticerci. Read More

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http://dx.doi.org/10.1186/s13104-018-3999-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293552PMC
December 2018
1 Read

[Impact of the neglected Cysticercus cellulose infection on mental health among school-aged children in Tibetan agricultural areas].

Zhong Nan Da Xue Xue Bao Yi Xue Ban 2018 Oct;43(10):1137-1144

Department of Health and Social Behavior Science, West China School of Public Health, Sichuan University, Chengdu 610041, China.

Objective: To determine the impact of Cysticercus cellulose (C. cellulose) infection on mental health among school-aged children in Tibetan agricultural areas of Sichuan Province.
 Methods: In October 2015, all primary schools located in Tibetan agricultural areas in Yajiang, Ruoergai, and Muli county of Sichuan Province were selected as the research sites. Read More

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http://dx.doi.org/10.11817/j.issn.1672-7347.2018.10.015DOI Listing
October 2018
1 Read

glutathione transferase fraction activates macrophages and favors the development of Th1-type response.

Biosci Rep 2019 Jan 18;39(1). Epub 2019 Jan 18.

Departamento de Microbiología y Parasitología, Facultad de Medicina, Universidad Nacional Autónoma de México, México 04510, CDMX

Glutathione (GSH) transferase (GST) is an essential enzyme in cestodes for the detoxification of xenobiotics. In , two GSTs (Ts25GST and Ts26GST kDa) were isolated as a fraction (SGSTF) by GSH-Sepharose-4B. Both are located on the tegument. Read More

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http://dx.doi.org/10.1042/BSR20181132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340957PMC
January 2019
1 Read

Overview of Taenia solium cysticercosis in West Africa.

Acta Trop 2019 Feb 7;190:329-338. Epub 2018 Dec 7.

Bristol Veterinary School, University of Bristol, Langford, Bristol, BS40 5DU, United Kingdom; School of Biological Sciences, Queen's University Belfast, 97, Lisburn Road, Belfast, BT9 7BL, United Kingdom.

Human and porcine cysticercosis is endemic in West Africa, where epilepsy is relatively common, but rarely reported due to fear of stigmatization. Neurocysticercosis, caused by Taenia solium, tends to affect the poor in developing countries and control is hampered by inadequate infrastructure and financial resources coupled with lack of adequate information about its significance and distribution. The risk factors for human cysticercosis are closely associated with the characteristics of smallholder or backyard pig farming systems prevalent in this region. Read More

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http://dx.doi.org/10.1016/j.actatropica.2018.12.012DOI Listing
February 2019
2 Reads

Detection of DNA in the Urine of Neurocysticercosis Patients.

Am J Trop Med Hyg 2019 Feb;100(2):327-329

W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland.

Neurocysticercosis (NCC), caused by larvae that reside in the central nervous system, results in serious public health and medical issues in many regions of the world. Current diagnosis of NCC is complex requiring both serology and costly neuroimaging of parasitic cysts in the brain. This diagnostic pipeline can be problematic in resource-constrained settings. Read More

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http://dx.doi.org/10.4269/ajtmh.18-0706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367601PMC
February 2019
1 Read

Oxfendazole: a promising agent for the treatment and control of helminth infections in humans.

Expert Rev Anti Infect Ther 2019 Jan 10;17(1):51-56. Epub 2018 Dec 10.

e Department of International Health , Johns Hopkins Bloomberg School of Public Health , Baltimore , MD , USA.

Introduction: Oxfendazole (methyl [5-(phenylsulphinyl)-1H benzimidazole-2-yl] carbamate) has a particularly long metabolic half-life in ruminants, and its metabolite fenbendazole also has anthelminthic action. A very limited number of drugs are available for the treatment of some zoonotic helminth infections, such as neurocysticercosis and echinococcosis. More recent work has expanded oxfendazole's nonclinical safety profile and demonstrated its safety and bioavailability in healthy human volunteers, thus advancing the possibility of a new and greatly needed option for antiparasitic treatment of geohelminths and tissue parasites. Read More

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http://dx.doi.org/10.1080/14787210.2018.1555241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376865PMC
January 2019
1 Read
3.461 Impact Factor

Subcutaneous nodules of cysticercosis as a sign of asymptomatic neurocysticercosis in an HIV positive patient.

Rev Soc Bras Med Trop 2018 Nov-Dec;51(6):861-863

Division of Dermatology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, Gauteng, South Africa.

Cysticercosis is caused by the hematogenous dissemination of the larval form (cysticercus) of Taenia solium. It can affect any organ or tissue in the body but commonly affects the subcutaneous tissue, central nervous system, eyes, and skeletal muscle. Skin lesions can assist as a marker in the diagnosis of asymptomatic neurocysticercosis in endemic areas. Read More

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http://dx.doi.org/10.1590/0037-8682-0178-2018DOI Listing
February 2019
4 Reads

Porcine cysticercosis (Taenia solium and Taenia asiatica): mapping occurrence and areas potentially at risk in East and Southeast Asia.

Parasit Vectors 2018 Nov 29;11(1):613. Epub 2018 Nov 29.

One Health Center for Zoonoses and Tropical Veterinary Medicine, Ross University School of Veterinary Medicine, Basseterre, Saint Kitts and Nevis.

Background: Due to the relative short life span and the limited spatial movement, porcine cysticercosis is an excellent indicator of current local active transmission. The aim of this study was to map at province-level, the occurrence of T. solium and T. Read More

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http://dx.doi.org/10.1186/s13071-018-3203-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267083PMC
November 2018
2 Reads
3.430 Impact Factor

Optic Nerve Cysticercosis at the Orbital Apex Presenting as Optic Neuritis.

Authors:
Neha Goel

J Ophthalmic Vis Res 2018 Oct-Dec;13(4):508-510

ICARE Eye Hospital and Postgraduate Institute, Noida, Uttar Pradesh, India.

Purpose: To describe an unusual presentation of ocular cysticercosis and highlight the role of imaging in diagnosis.

Case Report: A 33-year-old female presented with loss of vision in her right eye and features suggesting optic neuritis. Magnetic resonance imaging (MRI) of the brain and orbits revealed a cystic lesion with peripheral rim enhancement in the optic nerve substance at the orbital apex. Read More

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http://dx.doi.org/10.4103/jovr.jovr_251_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210869PMC
November 2018

Factors Associated With Cysticidal Treatment Response in Extraparenchymal Neurocysticercosis.

J Clin Pharmacol 2018 Nov 26. Epub 2018 Nov 26.

Neuroinflammation Unit, IIBM-UNAM/INNN/Facultad de Medicina- UNAM, Ciudad de México, México.

Extraparenchymal neurocysticercosis is the most severe form of cysticercosis, and response to treatment is suboptimal. We sought to determine how demographic and clinical characteristics and albendazole sulfoxide concentrations were related to cysticidal treatment response. We conducted a longitudinal study of 31 participants with extraparenchymal vesicular parasites who received the same treatment, albendazole 30 mg/kg/day for 10 days with dexamethasone 0. Read More

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http://doi.wiley.com/10.1002/jcph.1346
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http://dx.doi.org/10.1002/jcph.1346DOI Listing
November 2018
10 Reads

Bovine cysticercosis and taeniosis: The effect of an alternative post-mortem detection method on prevalence and economic impact.

Prev Vet Med 2018 Dec 12;161:1-8. Epub 2018 Oct 12.

Department of Veterinary Public Health and Food Safety, Faculty of Veterinary Medicine, Ghent University, 133 Salisburylaan, B-9820 Merelbeke, Belgium.

In Europe, bovine cysticercosis (BCC) is detected by routine meat inspection (MI) at the slaughterhouse. The prevalence of BCC in Belgium based on MI is estimated at 0.23%. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01675877183043
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http://dx.doi.org/10.1016/j.prevetmed.2018.10.006DOI Listing
December 2018
2 Reads

Evaluating Urban Taeniasis as a Threat to Cysticercosis Elimination in Northern Peru.

Am J Trop Med Hyg 2019 Jan;100(1):140-142

Oregon Health & Science University, Portland, Oregon.

Reintroduction of into a region in Peru where it had been eliminated prompted evaluation of the possibility of reintroduction from an urban reservoir of taeniasis. In a cross-sectional study of an adjacent urban area, we found low prevalence of taeniasis (4/1,621; 0.25%), suggesting minimal risk of parasite reintroduction into rural areas through this route. Read More

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http://dx.doi.org/10.4269/ajtmh.18-0767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335904PMC
January 2019
1 Read

Presentation of cysticercosis of the lateral pterygoid muscle as temporomandibular disorder: A diagnostic and therapeutic challenge.

J Indian Prosthodont Soc 2018 Oct-Dec;18(4):377-383

Division of Radiology, Department of Oral Medicine, University of Pennsylvania, PA, USA.

Orofacial pain can often be the chief complaint of many systemic disorders. Cysticercosis involving the lateral pterygoids may cause limitation of mouth opening and may mimic clinical symptoms of a temporomandibular disorder. A 37-year-old female presented with 1-month-old complaint of limited mandibular range of motion. Read More

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http://dx.doi.org/10.4103/jips.jips_129_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180738PMC
April 2018
8 Reads

Mathematical model of the life cycle of taenia-cysticercosis: transmission dynamics and chemotherapy (Part 1).

Theor Biol Med Model 2018 11 19;15(1):18. Epub 2018 Nov 19.

Department of Immunology, Biomedical Research Institute, Universidad Nacional Autónoma de México, Ciudad Universitaria, 04510, CDMX, Mexico.

Background: Taenia solium is the aetiological agent of human taeniasis, pig cysticercosis and human neurocysticercosis, which are serious public health problems, especially in developing countries.

Methods: A mathematical model of the transmission dynamics of taeniasis-cysticercosis is formulated. The model consists of a coupled system of differential equations, which are density-dependent equations for describing the flow of the parasite through the life cycle. Read More

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http://dx.doi.org/10.1186/s12976-018-0090-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241031PMC
November 2018
1 Read

Prevalence and distribution of Taenia solium cysticercosis in naturally infected pigs in Punjab, India.

PLoS Negl Trop Dis 2018 11 15;12(11):e0006960. Epub 2018 Nov 15.

Sydney School of Veterinary Science, The University of Sydney, Camden, NSW, Australia.

Background: Taenia solium (T. solium) cysticercosis remains a neglected zoonotic disease in India. The current study was planned to estimate the prevalence of T. Read More

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http://dx.plos.org/10.1371/journal.pntd.0006960
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http://dx.doi.org/10.1371/journal.pntd.0006960DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264866PMC
November 2018
9 Reads

Epidemiology of Taenia saginata taeniosis/cysticercosis: a systematic review of the distribution in southern and eastern Africa.

Parasit Vectors 2018 Nov 6;11(1):578. Epub 2018 Nov 6.

International Livestock Research Institute (ILRI), P.O. Box 30709, Nairobi, Kenya.

Background: The beef tapeworm, Taenia saginata, causing cysticercosis in bovines and taeniosis in humans, is thought to have a global distribution. In eastern and southern Africa, cattle production plays a crucial role in the economy, but a clear overview of the prevalence of T. saginata in the region is still lacking. Read More

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https://parasitesandvectors.biomedcentral.com/articles/10.11
Publisher Site
http://dx.doi.org/10.1186/s13071-018-3163-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219070PMC
November 2018
3 Reads

Towards a cysticercosis-free tropical resort island: A historical overview of taeniasis/cysticercosis in Bali.

Acta Trop 2019 Feb 29;190:273-283. Epub 2018 Oct 29.

Department of Parasitology, Asahikawa Medical University, Asahikawa, Japan. Electronic address:

Taeniasis and cysticercosis are known to be endemic in several Indonesian islands, although relatively little recent epidemiological data are available. As most Indonesian people are Muslims, taeniasis/cysticercosis caused by the pork tapeworm, Taenia solium, has a restricted presence in non-Muslim societies and is endemic only among some Hindu communities on the island of Bali. Bali has long been known to be endemic for taeniasis/cysticercosis; almost a century ago levels of cysticercosis of 20-30% were described in cattle and 2-3% in pigs. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0001706X183119
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http://dx.doi.org/10.1016/j.actatropica.2018.10.012DOI Listing
February 2019
14 Reads

A modified lateral flow assay, using serum, for the rapid identification of human and bovine cysticercosis in the absence of false positives.

Trans R Soc Trop Med Hyg 2019 Feb;113(2):101-104

Instituto de Investigaciones Biomédicas 'Dr. Francisco J. Triana-Alonso' Facultad de Ciencias de la Salud, Edo. Aragua. Universidad de Carabobo, Venezuela.

Background: Previously we reported the use of a monoclonal antibody-based (HP10) antigen (Ag) detection lateral flow assay (LFA) for the diagnosis of extraparenchymal neurocysticercosis (EP-NCC). The assay performed well when used with cerebrospinal fluid (CSF) samples but not with their paired serum samples, due to false-positive reactions in some known negative control cases.

Methods: Our novel modification involves pretreatment of serum samples using a combination of sodium deoxycholate and dithiothreitol. Read More

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http://fdslive.oup.com/www.oup.com/pdf/production_in_progres
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http://dx.doi.org/10.1093/trstmh/try116DOI Listing
February 2019
4 Reads

[A Social Network Perspective on the Transmission of Infections in Tibetan School Children in Sichuan].

Sichuan Da Xue Xue Bao Yi Xue Ban 2018 Sep;49(5):754-758

Department of Health and Social Behavior Science, West China School of Public Health, Sichuan University, Chengdu 610041, China.

Objective: To determine the transmission characteristics of infections from a social network perspective in Tibetan school children in Sichuan.

Methods: A cluster sampling strategy was adopted to select two primary schools with high level of infections in the Tibetan agriculture areas of Liangshan prefecture, Sichuan province. All of the students from the selected schools were enrolled in the study. Read More

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September 2018
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Epidemiology of taeniosis/cysticercosis in Europe, a systematic review: eastern Europe.

Parasit Vectors 2018 Oct 30;11(1):569. Epub 2018 Oct 30.

Department of Veterinary Public Health and Food Safety, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820, Merelbeke, Belgium.

Background: Taenia solium and Taenia saginata are food-borne parasites of global importance. In eastern Europe only fragmented information is available on the epidemiology of these zoonotic parasites in humans and animal populations. In particular for T. Read More

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https://parasitesandvectors.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s13071-018-3153-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208121PMC
October 2018
14 Reads

Response to letter to editor from Dr Sandeep Moudgil: is the biopsy warranted for cerebral cysticercosis?

Authors:
Z Liu Z Zeng F Lin

QJM 2019 Jan;112(1):75

Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, China.

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http://dx.doi.org/10.1093/qjmed/hcy254DOI Listing
January 2019
1 Read