7,284 results match your criteria Cystectomy Radical


Clinical outcomes of robot-assisted radical cystectomy and continent urinary diversion.

Scand J Urol 2019 Apr 16:1-8. Epub 2019 Apr 16.

a Department of Molecular Medicine and Surgery, Section of Urology , Karolinska Institut , Stockholm , Sweden.

Robot-assisted radical cystectomy (RARC) with intracorporeal orthotopic neobladder (ONB) can be recognized to be the supreme discipline in urological pelvic surgery. The utilization of RARC with intracorporeal urinary diversion (ICUD) has increased during the last 15 years. This increase is primarily noted for ICUD with ileal conduits, but with a lesser extent also for IC neobladders, with an increase from 7% in 2005 to 17% in 2016. Read More

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https://www.tandfonline.com/doi/full/10.1080/21681805.2019.1
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http://dx.doi.org/10.1080/21681805.2019.1598486DOI Listing
April 2019
2 Reads

Re: Impact of Adjuvant Chemotherapy in Patients with Adverse Features and Variant Histology at Radical Cystectomy for Muscle-invasive Carcinoma of the Bladder: Does Histologic Subtype Matter?

Eur Urol 2019 Apr 12. Epub 2019 Apr 12.

Department of Urology, Bichat-Claude Bernard Hospital, Assistance Publique-Hôpitaux de Paris, Paris Descartes University, Paris, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03022838193027
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http://dx.doi.org/10.1016/j.eururo.2019.03.040DOI Listing
April 2019
1 Read

Re: Extended Versus Limited Lymph Node Dissection in Bladder Cancer Patients Undergoing Radical Cystectomy: Survival Results from a Prospective, Randomized Trial.

Eur Urol 2019 Apr 12. Epub 2019 Apr 12.

Division of Urology, Department of Surgical Sciences, San Giovanni Battista Hospital, University of Studies of Torino, Turin, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2019.03.042DOI Listing

TUMOR BUDDING: PROGNOSTIC VALUE IN MUSCLE-INVASIVE BLADDER CANCER.

Urology 2019 Apr 12. Epub 2019 Apr 12.

Department of Pathology, Hospital University La Fe, Valencia, Spain. Electronic address:

Objetives: To assess if 'tumour budding' (TB) behaves as a poor prognostic factor in muscle-invasive bladder carcinoma (MIBC). TB is the presence of tumour cells isolated or in small groups of fewer than five cells located at the tumour invasion front.

Material And Methods: Retrospective study of 106 patients with MIBC who underwent radical cystectomy. Read More

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http://dx.doi.org/10.1016/j.urology.2019.04.006DOI Listing
April 2019
1 Read

[Clinical experiences of laparoscopic radical cystectomy and urinary diversion in the elderly patients with bladder cancer].

Zhonghua Yi Xue Za Zhi 2019 Apr;99(14):1101-1105

Department of Urology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.

To optimize the surgical procedures of laparoscopic radical cystectomy and urinary diversion for the elderly patients with bladder cancer, generalize operating technique, summarize clinical experiences. From July 2004 to October 2016, laparoscopic radical cystectomy (LRC) and urinary diversion was performed in 68 elderly patients (≥75 years old) diagnosed with bladder cancer in urology department of Beijing Chaoyang Hospital, Capital Medical University, and the relevant clinical and follow-up data were retrospectively reviewed. All the patients were pathologically diagnosed and their perioperative data, postoperative pathological results, postoperative complications and follow-up outcomes were recorded and analyzed. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.14.013DOI Listing
April 2019
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A new modification of tubeless cutaneous ureterostomy following radical cystectomy.

Int Urol Nephrol 2019 Apr 13. Epub 2019 Apr 13.

Department of Urology, "Artmed" Medical Center, Yerevan, Armenia.

Purpose: Cutaneous ureterostomy is a well-established surgical technique of incontinent urinary diversion treatment. However, stoma stenosis limits widespread utilization of this technique. We present our modification of constructing single-site tubeless cutaneous ureterostomy aiming to reduce stomal complications and improve catheter-free rate of those patients. Read More

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http://link.springer.com/10.1007/s11255-019-02145-x
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http://dx.doi.org/10.1007/s11255-019-02145-xDOI Listing
April 2019
2 Reads

Influence of preoperative hydronephrosis and ureteral orifice involvement in the survival of patients undergoing radical cystectomy: A retrospective comparative study.

Turk J Urol 2019 Apr 3. Epub 2019 Apr 3.

Department of Urology, Health Sciences University, Bozyaka Training and Research Hospital, İzmir, Turkey.

Objective: The aim of the present study was to evaluate the influence of preoperative hydronephrosis and ureteral orifice involvement (UOI) on survival of patients undergoing radical cystectomy (RC) for bladder cancer (BC).

Material And Methods: A total of 162 patients with BC underwent RC between January 2006 and March 2017. Patients were divided into two groups for both presences of preoperative hydronephrosis and orifice involvement at final pathology. Read More

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http://dx.doi.org/10.5152/tud.2019.09515DOI Listing
April 2019
3 Reads

Oncologic outcomes after robot-assisted versus open radical cystectomy: a systematic review and meta-analysis.

World J Urol 2019 Apr 11. Epub 2019 Apr 11.

Department of Urology and Comprehensive Cancer Center, Vienna General Hospital, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.

Purpose: The efficacy of RARC in oncologic outcomes compared ORC is controversial. We assess potential differences in oncologic outcomes between robot-assisted radical cystectomy (RARC) and open radical cystectomy (ORC).

Methods: We performed the literature search systematically according to the Preferred Reporting Items for Systematic Review and Meta-analysis statement. Read More

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http://dx.doi.org/10.1007/s00345-019-02708-8DOI Listing

Successful arthroscopic treatment of refractory and complicated popliteal cyst associated with rheumatoid arthritis in combination with osteoarthritis: case series and literature review.

Rheumatol Int 2019 Apr 11. Epub 2019 Apr 11.

Division of Rheumatology, Department of Internal Medicine, Hanyang University Guri Hospital, 153, Gyeongchunro, Guri, Gyeonggi-do, 11923, South Korea.

Although popliteal cysts are most frequently identified in patients with osteoarthritis (OA), they may occur in patients with rheumatoid arthritis (RA), in which serious complicated cases such as cyst rupture can be developed. The objective of this study was to report four patients with RA (six knees) in combination with OA with a brief review of literature of previous similar published cases. This is a retrospective review of case records of patients with refractory and/or complicated popliteal cysts, who have successfully treated with arthroscopic intervention. Read More

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http://dx.doi.org/10.1007/s00296-019-04278-9DOI Listing
April 2019
1 Read

Selection of patients and benefit of immediate radical cystectomy for non-muscle invasive bladder cancer.

Transl Androl Urol 2019 Feb;8(1):101-107

Department of Urology, Royal Hallamshire Hospital, Sheffield, UK.

Bladder cancer (BC) is a common disease in both sexes and majority of cases present as non-muscle invasive BC (NMIBC). The percentage of NMIBC progressing to muscle invasive BC (MIBC) varies between 25% and 75% and currently there are no reliable molecular markers that may predict the outcome of high-risk (HR) NMIBC. Transurethral resection of the bladder tumour (TURBT) with intravesical bacillus Calmette-Guérin (BCG) or immediate radical cystectomy (RC) are the current gold standard treatment options. Read More

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http://dx.doi.org/10.21037/tau.2018.09.06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414338PMC
February 2019
1 Read

Device-assisted intravesical therapy for non-muscle invasive bladder cancer.

Authors:
Kees Hendricksen

Transl Androl Urol 2019 Feb;8(1):94-100

Department of Urology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.

Non-muscle invasive bladder cancer (NMIBC) is a challenging disease, with a high risk of recurrence and even progression to muscle invasive disease. The present standard treatment is suboptimal, and consists of a complete transurethral resection of the visible bladder tumour(s), followed by prophylactic intravesical instillations mitomycin-C (MMC) or bacillus Calmette-Guérin (BCG). In search for higher efficacy, several adjuvant device-assisted intravesical therapies are developed. Read More

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http://dx.doi.org/10.21037/tau.2018.09.09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414348PMC
February 2019
3 Reads

The current role of circulating biomarkers in non-muscle invasive bladder cancer.

Transl Androl Urol 2019 Feb;8(1):61-75

Department of Urology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Non-muscle invasive bladder cancer (NMIBC) is characterized by its high rate of disease recurrence and relevant disease progression rates. Up to today clinical models are insufficiently predicting outcomes for reliable patient counseling and treatment decision-making. This particularly is a serious problem in patients with high-risk NMIBC who are at high risk for failure of local treatment and thus candidates for early radical cystectomy or even systemic (neoadjuvant) chemotherapy. Read More

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http://dx.doi.org/10.21037/tau.2018.11.05DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414344PMC
February 2019
2 Reads

The rational and benefits of the second look transurethral resection of the bladder for T1 high grade bladder cancer.

Transl Androl Urol 2019 Feb;8(1):46-53

Department of Urology and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.

The second look transurethral resection of the bladder (TURB) represents a fundamental step in the treatment of papillary non-muscle invasive bladder cancer (NMIBC); it is therefore recommended by all guidelines. However, not all the literature agrees on its staging value and its ability to improve oncological outcomes of patients. Therefore, the purpose of this review is to evaluate the strengths and weaknesses of second look TURB, trying to depict its evolving role in the management of high grade NMIBC. Read More

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http://dx.doi.org/10.21037/tau.2018.10.19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414350PMC
February 2019
1 Read

Histological variants in non-muscle invasive bladder cancer.

Transl Androl Urol 2019 Feb;8(1):34-38

Klinik für Urologie, Luzerner Kantonsspital, Lucerne 6004, Switzerland.

Several studies evaluated the role of histological variants on oncological outcomes after radical cystectomy (RC) and they were found significantly associated with worse recurrence and survival. Sparse data exists regarding the role variant histology in non-muscle invasive diseases: assessing their relationship with recurrence and progression is important to understand the most effective treatment and follow-up schedule. For these reasons, the aim of the present non-systematic review was to assess the literature on variant histology in non-muscle invasive bladder cancer (BCa). Read More

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http://dx.doi.org/10.21037/tau.2019.01.09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414352PMC
February 2019
1 Read

Genital-Sparing Cystectomy versus Standard Urethral-Sparing Cystectomy Followed with Orthotopic Neobladder in Women with Bladder Cancer: Incidence and Causes of Hypercontinence with an Ultrastructure Study of Urethral Smooth Muscles.

Open Access Maced J Med Sci 2019 Mar 27;7(6):978-981. Epub 2019 Mar 27.

Department of Urology, Theodor Bilharz Research Institute, Cairo, Egypt.

Background: Bladder cancer in women is an indication for radical cystectomy (RC) when the tumour is confined muscle-invasive bladder cancer (MIBC) of T2 N0M0, or high risk progressive non-muscle invasive bladder cancer (NMIBC). Radical cystectomy is either genital-sparing cystectomy (GSC) or standard urethra-sparing cystectomy (USC) that is followed with orthotopic ileal neobladder (ONB). Post-operative chronic retention "Hypercontinence" had been reported in different series following URS or GSC and ONB. Read More

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http://dx.doi.org/10.3889/oamjms.2019.206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454182PMC
March 2019
1 Read

Laparoscopic radical cystectomy in octogenarians: analysis of a Japanese multicenter cohort.

Int J Clin Oncol 2019 Apr 10. Epub 2019 Apr 10.

Department of Urology, Kyoto University Hospital, Kyoto, Japan.

Backgrounds: This study aimed to describe the morbidity and mortality in older patients undergoing laparoscopic radical cystectomy (LRC) and compare the outcomes of LRC between octogenarians and younger patients (< 80 years) in a Japanese multicenter cohort.

Methods: We identified 433 patients (80 octogenarians) who underwent LRC in a retrospective multicenter database from 10 institutions. The perioperative outcomes and the 90-day and late (> 90-day) complications according to the Clavien-Dindo classification were compared between the octogenarians and younger patients. Read More

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http://dx.doi.org/10.1007/s10147-019-01446-6DOI Listing
April 2019
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Diagnostic utility of GATA3 immunohistochemical expression in urothelial carcinoma.

Indian J Pathol Microbiol 2019 Apr-Jun;62(2):244-250

Department of Pathology, King George Medical University, Lucknow, Uttar Pradesh, India.

Aims: This study aims to explore the utility of GATA binding protein 3, a zinc finger transcription factor, expression in genitourinary carcinoma, especially urothelial carcinoma.

Settings And Design: It is a prospective study where 74 consecutive cases of urothelial carcinoma along with 10 cases each of prostatic adenocarcinoma (PC) and conventional clear cell renal cell carcinoma were included between August 2016 and January 2017.

Methods And Materials: All the cases were histopathologically evaluated and immunohistochemically stained for GATA binding protein 3. Read More

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http://dx.doi.org/10.4103/IJPM.IJPM_228_18DOI Listing
April 2019
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Single-Port Robotic Intracorporeal Ileal Conduit Urinary Diversion During Radical Cystectomy Using the SP Surgical System: Step-by-Step Technique.

Urology 2019 Apr 6. Epub 2019 Apr 6.

Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio.

Objectives: To describe the step-by-step technique for robotic intracorporeal ileal conduit urinary diversion (ICUD) following radical cystectomy performed by using the novel da Vinci SP surgical system (Intuitive Surgical, Sunnyvale, CA).

Methods: Four consecutive patients (2 males and 2 female) were initially counseled for robotic cystectomy with ICUD performed by using the da Vinci SP surgical system. Surgeries were performed by duplicating the steps of the institutional approach for intracorporeal ileal conduit urinary diversion performed with the multi-arms robotic platform. Read More

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http://dx.doi.org/10.1016/j.urology.2019.03.023DOI Listing
April 2019
2 Reads

Long-term Changes in Renal Function, Blood Electrolyte Levels, and Nutritional Indices after Radical Cystectomy and Ileal Conduit in Patients with Bladder Cancer.

Urol J 2019 Apr 7. Epub 2019 Apr 7.

Department of Urology, Nara Medical University, 840 Shijo-cho, Kashihara-shi, Nara 634-8522, Japan.

Purpose: To assess the long-term changes in renal function, blood electrolyte levels, and nutritional indices after radical cystectomy and ileal conduit in patients with bladder cancer.

Patients And Methods: In 129 patients who underwent radical cystectomy and ileal conduit, we evaluated clinicopathologic features, complications, and the change in the estimated glomerular filtration rate (eGFR) from baseline to 1, 2, 3, 4, 5, and 10 years postoperatively. Two nutritional indices, the geriatric nutritional risk index (GNRI) and prognostic nutrition index (PNI), were calculated with laboratory tests. Read More

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http://dx.doi.org/10.22037/uj.v0i0.4531DOI Listing
April 2019
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The impact of postoperative inflammatory biomarkers on oncologic outcomes of bladder cancer.

Prog Urol 2019 Apr 3. Epub 2019 Apr 3.

University Clinics of Brussels, Department of Urology, Hôpital Erasme, Université Libre de Bruxelles, Route de Lennik 808, Brussels, Belgium.

Introduction: The clinical impact of inflammatory biomarkers has been evaluated in urothelial bladder cancer. However, data are limited to preoperative values and there is paucity of evidence of the role of postoperative measurement of those biomarkers. The aim of the current study was to determine the association of inflammatory biomarkers as neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), hemoglobin to platelet ratio (HPR) and C-reactive protein (CRP), before and after radical cystectomy, with recurrence and survival of bladder cancer. Read More

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http://dx.doi.org/10.1016/j.purol.2019.02.008DOI Listing
April 2019
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Molecular characterization of neuroendocrine-like bladder cancer.

Clin Cancer Res 2019 Apr 5. Epub 2019 Apr 5.

Vancouver Prostate Centre, Department of Urologic Sciences, University of British Columbia

Purpose: Neuroendocrine (NE) bladder carcinoma is a rare and aggressive variant. Molecular subtyping studies have found that 5-15% of muscle-invasive bladder cancer (MIBC) have transcriptomic patterns consistent with NE bladder cancer in the absence of NE histology. The clinical implications of this NE-like subtype have not been explored in depth. Read More

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http://dx.doi.org/10.1158/1078-0432.CCR-18-3558DOI Listing
April 2019
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Concomitant primary ovarian paraganglioma neuroendocrinal differentiated urothelial tumor in a BOTOX-injected bladder: A case report.

Int J Surg Case Rep 2019 Mar 28;57:122-125. Epub 2019 Mar 28.

Urology Department, Urology and Nephrology Center, Mansoura University, Egypt.

Introduction: There is no reported data for patients with malignant bladder Botox injection related outcomes. Herein, we reported effect of Botox injection in case of BCG cystitis. In addition, reporting of rare incidence of both primary neuroendocrine differentiation of bladder tumor and primary ovarian paraganglioma post cystectomy. Read More

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http://dx.doi.org/10.1016/j.ijscr.2019.03.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447811PMC
March 2019
1 Read

Enhanced Recovery after Radical Cystectomy.

Curr Opin Urol 2019 May;29(3):227-238

Department of Urology, Medical University of Vienna, Vienna, Austria.

Purpose Of Review: Enhanced Recovery after Surgery (ERAS) programs are multimodal and interdisciplinary protocols, which aim to accelerate patient recovery and improve surgical outcomes through standardized perioperative care. In this review, we summarized the items included in most currently utilized protocols for patients undergoing radical cystectomy and we discussed the reported outcomes after the implementation.

Recent Findings: Current protocols are mostly extrapolated from the colorectal surgery literature, and solid evidence in radical cystectomy is limited. Read More

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http://Insights.ovid.com/crossref?an=00042307-201905000-0000
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http://dx.doi.org/10.1097/MOU.0000000000000594DOI Listing
May 2019
3 Reads

Period-specific mean annual hospital volume of radical cystectomy is associated with outcome and perioperative quality of care: a nationwide population-based study.

BJU Int 2019 Apr 5. Epub 2019 Apr 5.

Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.

Objective: To investigate the association between hospital volume on overall survival (OS), cancer-specific survival (CSS), and quality of care defined as use of extended lymphadenectomy, continent reconstruction, neoadjuvant chemotherapy and treatment delay less than 3 months.

Materials And Methods: We used Bladder Cancer Data Base Sweden (BladderBaSe) to study survival and indicators of perioperative quality of care in all 3172 patients who underwent radical cystectomy for primary invasive bladder cancer stage T1-T3 in Sweden 1997-2014. The period-specific mean annual hospital volume (PSMAV) during the 3 years preceding surgery was applied as an exposure and analysed using univariate and multivariate mixed models, adjusting for tumour and nodal stage, age, gender, comorbidity, educational level and neoadjuvant chemotherapy. Read More

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http://dx.doi.org/10.1111/bju.14767DOI Listing
April 2019
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Which treatment is best for patients with AJCC stage IV bladder cancer?

Int Urol Nephrol 2019 Apr 4. Epub 2019 Apr 4.

Department of Urology, Shanghai Tenth People's Hospital, Tongji University, No. 301, Yanchang Road, Jing'an District, Shanghai, 200072, China.

Purpose: We sought to identify the method that could obtain the best survival rate for AJCC stage IV bladder cancer (BCa) patients.

Methods: Patients with AJCC stage IV BCa diagnosed between 2004 and 2015 were identified using the Surveillance, epidemiology and end results (SEER) database. Kaplan-Meier curves and log-rank test were used for overall survival (OS) and cancer-specific survival (CSS). Read More

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http://dx.doi.org/10.1007/s11255-019-02105-5DOI Listing
April 2019
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Urothelial Carcinoma Recurrence in an Orthotopic Neobladder without Urethral or Upper Urinary Tract Involvement.

Case Rep Urol 2019 5;2019:8458706. Epub 2019 Mar 5.

Department of Urology, Loyola University Medical Center, Maywood, IL, USA.

We describe a case of a 71-year-old male with an isolated recurrence of urothelial carcinoma in an ileal neobladder without involvement of the upper urinary tract or urethra. He was diagnosed with high grade urothelial carcinoma involving a bladder diverticulum with associated carcinoma in situ. He underwent a radical cystectomy and orthotopic Studer ileal neobladder. Read More

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http://dx.doi.org/10.1155/2019/8458706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425315PMC
March 2019
2 Reads

The Short-Term Effects of Tolterodine on Nocturnal Incontinence after Orthotopic Ileal Neobladder: A Randomized Crossover Placebo-Controlled Study.

BJU Int 2019 Apr 4. Epub 2019 Apr 4.

Urology and nephrology center, Mansoura University, Egypt.

Objectives: To assess the effect of Tolterodine in the treatment of nocturnal incontinence (NI) after ileal orthotopic neobladder (ONB).

Material And Methods: This is a prospective randomized placebo-controlled cross-over study (clinicaltrials. gov: NCT02877901). Read More

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http://dx.doi.org/10.1111/bju.14769DOI Listing

Intracorporeal neobladder.

Arch Esp Urol 2019 04;72(3):309-317

Hospital Universitario Puerta de Hierro. Madrid. Spain.

Objective: It is well known that RARC with intracorporeal diversion is being increasingly performed worldwide. In this article, we review the current situation of the intracorporeal neobladder.

Methods: We discuss the principles of intracorporeal orhotopic diversion, focusing on the most relevant: The Karolinska-modified Studer neobladder, the University of Southern California-modified Studer neobladder. Read More

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April 2019
7 Reads

Robotic intracorporeal ileal conduit: Technical aspects.

Arch Esp Urol 2019 04;72(3):299-308

Catherine & Joseph Aresty Department of Urology. USC Institute of Urology and the Keck School of Medicine. University of Southern California. Los Angeles. CA. USA.

Objective: To present a review of the technical aspects of robotic intracorporeal ileal conduit  (IC) reconstruction after robot assisted radical cystectomy (RARC). METHODS: A non-systematic review is performed in order  to summarize technical aspects on robot assisted ileal conduit procedure following radical cystectomy in patients with muscle invasive bladder cancer.  RESULTS: Radical cystectomy with pelvic lymph node dissection and urinary diversion is the gold-standard therapy for localized muscle-invasive bladder cancer. Read More

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April 2019
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Robotic radical cystectomy.

Arch Esp Urol 2019 04;72(3):293-298

Department of Urology. Fundació Puigvert. Universitat Autonoma de Barcelona. Barcelona. Spain.

Objectives: Radical cystectomy (RC) is one of the most complex and morbid surgical procedures in Urology. Several retrospective and prospective studies have demonstrated that robotic-assisted RC (RARC) represents a minimally invasive alternative to open surgery, showing non-inferiority in mid-term oncological outcomes. Moreover, important advantages related with  perioperative complications have also been published. Read More

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Incidence and microbiology of post-operative infections after radical cystectomy and ureteral stent removal; a retrospective cohort study.

BMC Infect Dis 2019 Apr 3;19(1):303. Epub 2019 Apr 3.

Radboud center for infectious diseases, Radboud university medical center, P.O. Box 9101, 6500, HB, Nijmegen, the Netherlands.

Background: Post-operative infections are frequent after radical cystectomy with urinary diversion surgery (UDS). Reduction of post-operative infections necessitates appropriate peri-operative antimicrobial prophylaxis targeting causative bacteria. We assessed the incidence and microbiology of infections in the 30-day post-operative period after UDS and investigated effectiveness of the currently used peri-operative antibacterial prophylaxis. Read More

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https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128
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http://dx.doi.org/10.1186/s12879-019-3932-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448312PMC
April 2019
1 Read

Association Between Preoperative Hydronephrosis and Prognosis After Radical Cystectomy Among Patients With Bladder Cancer: A Systemic Review and Meta-Analysis.

Front Oncol 2019 19;9:158. Epub 2019 Mar 19.

Department of Urology, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, South Korea.

Preoperative hydronephrosis (HN) might be associated with adverse outcomes in patients who underwent radical cystectomy (RC). The aim of this study was to evaluate the effect of preoperative HN on the oncological outcomes in patients with bladder cancer who underwent RC by performing a systemic review and meta-analysis. A systematic literature review in PubMed, EMBASE, and Scopus was conducted by searching the terms "bladder cancer," "cystectomy," and "hydronephrosis" until December 2016, in accordance with the Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) guidelines. Read More

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https://www.frontiersin.org/article/10.3389/fonc.2019.00158/
Publisher Site
http://dx.doi.org/10.3389/fonc.2019.00158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433994PMC
March 2019
4 Reads

Survival after radiotherapy versus radical cystectomy for primary muscle-invasive bladder cancer: A Swedish nationwide population-based cohort study.

Cancer Med 2019 Apr 1. Epub 2019 Apr 1.

Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.

Background: Studies of survival comparing radical cystectomy (RC) and radiotherapy for muscle-invasive bladder cancer have provided inconsistent results and have methodological limitations. The aim of the study was to investigate risk of death after radiotherapy as compared to RC.

Methods: We selected patients with muscle-invasive urothelial carcinoma without distant metastases, treated with radiotherapy or RC from 1997 to 2014 in the Bladder Cancer Data Base Sweden (BladderBaSe) and estimated absolute and relative risk of bladder cancer death and all-cause death. Read More

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http://dx.doi.org/10.1002/cam4.2126DOI Listing
April 2019
2 Reads

The Cancer of the Bladder Risk Assessment (COBRA) score for predicting cancer-specific survival after radical cystectomy for urothelial carcinoma of the bladder: External validation in a cohort of Korean patients.

Urol Oncol 2019 Mar 29. Epub 2019 Mar 29.

Department of Urology, Seoul National University Hospital, Seoul, Korea. Electronic address:

Objectives: To validate the Cancer of the Bladder Risk Assessment (COBRA) score for predicting cancer-specific survival (CSS) in comparison with the American Joint Committee on Cancer (AJCC) staging system using an external cohort of urothelial carcinoma of the bladder (UCB) from South Korea.

Materials And Methods: The final validation cohort consisted of 855 patients who underwent radical cystectomy (RC) for UCB in a single institution. The impact of the COBRA score on CSS was estimated using Cox proportional hazard models. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10781439193009
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http://dx.doi.org/10.1016/j.urolonc.2019.03.006DOI Listing
March 2019
2 Reads

Post-surgical complications in patients with bladder cancer treated with cystectomy: Differences between open and laparoscopic approach.

Actas Urol Esp 2019 Mar 29. Epub 2019 Mar 29.

Servicio de Urología, Hospital General Universitario Gregorio Marañón, Madrid, España.

Introduction: Minimally invasive surgery regarding cystectomy has not had the same development as other urological surgeries. This could be due to the lack of published studies defining the advantages of this approach versus open surgery.

Objectives: The main objective of this study is to establish the role of minimally invasive surgery, laparoscopic radical cystectomy, versus open surgery by analyzing their perioperative complications. Read More

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http://dx.doi.org/10.1016/j.acuro.2018.12.001DOI Listing

Pubis bone osteomyelitys after robotic radical cystectomy with continent intracorporeal urinary diversion: Multidisciplinary approach to a complex situation.

Arch Ital Urol Androl 2019 Mar 29;91(1):63-67. Epub 2019 Mar 29.

Robotic Urology and Mini Invasive Urologic Surgery Unit, Abano Terme Hospital, Abano Terme (PD).

Pubic bone osteomyelitis is a rare infectious condition which is characterized by a complex diagnostic and therapeutic workup, due to its various clinical manifestations. Among the many causes of this condition, urinary fistula is the most common in case of previous urological procedures. In order to solve this complication, it is crucial to treat both the fistula and (moreover) the infectious locus arising from it, because treating the fistula alone does not provide any control on the infectious noxa. Read More

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http://dx.doi.org/10.4081/aiua.2019.1.63DOI Listing
March 2019
4 Reads

Posterior muscle-fascial reconstruction and knotless urethro-neo bladder anastomosis during robot-assisted radical cystectomy: Description of the technique and its impact on urinary continence.

Arch Ital Urol Androl 2019 Mar 29;91(1):5-10. Epub 2019 Mar 29.

Department of Urology, Policlinic of Abano Terme (Padova); Department of Urology, S. Orsola-Malpighi Hospital, University of Bologna.

Objective: The aim of our study is to describe the use of posterior muscle-fascial reconstruction during urethro-ileal anastomosis in bladder cancer (BC) patients submitted to robot-assisted radical cystectomy (RC) with orthotopic neobladder (ON) and its role in facilitating day- and night-time continence recovery during a 12-month follow up.

Materials And Methods: We prospectively collected data from 42 consecutive patients who underwent RARC with totally intracorporeal ON and extended pelvic lymph node dissection (PLND) at our Institution from June 2014 to October 2017. Prior to the urethro-neobladder anastomosis we reconstructed the Denonvilliers Fascia (DF) as previously described for radical prostatectomy using a bidirectional barbed suture. Read More

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http://dx.doi.org/10.4081/aiua.2019.1.5DOI Listing
March 2019
2 Reads

Contemporary North-American Assessment of Robot-assisted Surgery Rates and Total Hospital Charges for Major Surgical Uro-oncological Procedures.

J Endourol 2019 Mar 30. Epub 2019 Mar 30.

University of Montreal Health Center, Cancer Prognostics and Health Outcomes Unit, Montreal, Quebec, Canada.

Background: The role of robot-assistance is increasingly gaining importance among all major surgical uro-oncological procedures (MSUPs). However, contemporary analyses showed that total hospital charges (THCGs) related to robot-assisted procedures exceed those of open procedures. Based on increasing familiarity with robot-assisted surgery, we postulated that THCGs may have decreased over the past half-decade. Read More

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http://dx.doi.org/10.1089/end.2018.0840DOI Listing
March 2019
2 Reads

Frailty and Greater Health Care Resource Utilization Following Major Urologic Oncology Surgery.

Eur Urol Oncol 2019 Feb 6;2(1):21-27. Epub 2018 Jul 6.

Department of Urology, Weill Cornell Medicine-New York Presbyterian Hospital, New York, NY, USA.

Background: In the setting of value-based care, it is critical to improve our understanding of surgical risk and greater health care resource utilization (HRU) as it relates to frailty.

Objective: To evaluate the impact of frailty on HRU and surgical morbidity in urologic oncology surgery using the five-item frailty index.

Design, Setting, And Participants: A retrospective cohort study was conducted using subjects from the 2012-2016 American College of Surgeons National Surgical Quality Improvement Program who underwent radical cystectomy or minimally invasive or open radical prostatectomy, radical nephrectomy, or partial nephrectomy. Read More

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http://dx.doi.org/10.1016/j.euo.2018.06.005DOI Listing
February 2019
1 Read

Glandular differentiation in pT1 urothelial carcinoma of bladder predicts poor prognosis.

Sci Rep 2019 Mar 29;9(1):5323. Epub 2019 Mar 29.

Department of Urology, Binzhou Medical University Hospital, Binzhou, 256603, China.

To evaluate the effect of glandular differentiation (GD) on tumor recurrence and progression of pT1 bladder urothelial carcinoma (UC). We performed a retrospective analysis of 82 bladder urothelial carcinoma with glandular differentiation (UCGD) patients which was pathologically diagnosed as pT1, 166 patients of pT1 UC of bladder without histologic variants served as controls. Patients of UCGD were more likely to have higher recurrence (P = 0. Read More

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http://dx.doi.org/10.1038/s41598-019-41844-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441090PMC
March 2019
4 Reads

Retraction notice to "Modified U-shaped ileal neobladder after radical cystectomy: assessment of functional outcomes and complications in Chinese patients".

Urol Oncol 2019 04;37(4):296

Department of Urology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.1016/j.urolonc.2019.03.013DOI Listing
April 2019
2.768 Impact Factor

Usage of Intravenous Lidocaine Infusion with Enhanced Recovery Pathway in Patients Scheduled for Open Radical Cystectomy: A Randomized Trial.

Pain Physician 2019 03;22(2):E71-E80

Asyut Urology and Nephrology Hospital, Assiut University, Asyut, Egypt.

Background: Intravenous lidocaine infusion (IVLI) reduces postoperative pain and hastens the return of bowel function.

Objectives: We aimed to compare the effects of adding lidocaine infusion to enhanced recovery pathway (ERP) on acute rehabilitation protocol.

Study Design: This study uses a double-blind, randomized design with allocation concealment in a 2-armed parallel group format among patients undergoing open radical cystectomy (RC). Read More

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March 2019
1 Read

Short- and long-term survival has improved after radical cystectomy for bladder cancer in Québec during the years 2000-2015.

J Surg Oncol 2019 Mar 28. Epub 2019 Mar 28.

Department of Surgery, McGill University Health Centre, Montreal, Québec, Canada.

Background And Objectives: We evaluated the short- and long-term outcome in bladder cancer (BC) patients treated with radical cystectomy (RC) in Québec (Canada).

Methods: Data were collected from provincial registries on all BC patients who underwent RC in Québec province in 2000-2015. Outcomes were hospitalization rates and survival. Read More

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http://dx.doi.org/10.1002/jso.25456DOI Listing
March 2019
3 Reads

Development of a New Comorbidity Assessment Tool for Specific Prediction of Perioperative Mortality in Contemporary Patients Treated with Radical Cystectomy.

Ann Surg Oncol 2019 Mar 27. Epub 2019 Mar 27.

Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, QC, Canada.

Purpose: The Deyo adaptation of the Charlson comorbidity index (DaCCI), which relies on 17 comorbid condition groupings defined with 200 ICD-9-CM diagnostic codes, lacks specificity in the context of radical cystectomy (RC) for bladder cancer (BCa). We attempted to develop a new comorbidity assessment tool based on individual comorbid conditions and/or BCa manifestations for specific prediction of perioperative mortality after RC.

Methods: We relied on 7076 T1-T4 nonmetastatic BCa patients treated with RC between 2000 and 2009 in the SEER-Medicare linked database. Read More

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http://dx.doi.org/10.1245/s10434-019-07313-yDOI Listing
March 2019
1 Read

Concomitant carcinoma in situ may not be a prognostic factor for patients with bladder cancer following radical cystectomy: a PRISMA-compliant systematic review and meta-analysis.

World J Urol 2019 Mar 27. Epub 2019 Mar 27.

Department of Urology, Affiliated Jiang-yin Hospital of the Southeast University Medical College, 163 Shoushan Road, Jiang-Yin, 214400, Jiangsu Province, China.

Background: Numerous recent studies have shown that concomitant carcinoma in situ (CIS) can be closely associated with the prognosis of patients with bladder cancer (BCa). However, the prognostic value of CIS in BCa is still not conclusive. Hence, we performed a systematic review and meta-analysis to explore the association between CIS and clinicopathological features and the prognostic value for BCa following radical cystectomy. Read More

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http://dx.doi.org/10.1007/s00345-019-02738-2DOI Listing
March 2019
1 Read

[Surgical treatment for inflammatory myofibroblastic tumor in genito-urinary system: a study of 15 cases].

Zhonghua Yi Xue Za Zhi 2019 Mar;99(12):947-949

Department of Head and Neck Surgery, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.

To present 15 cases of inflammatory myofibroblastic tumor (IMT) in genitor-urinary system, and analyze the characteristics, diagnosis and treatment of the disease. The diagnostic and therapeutic process of 15 confirmed cases admitted to Sun Yat-sen University Cancer Center between March 2009 and September 2017 were retrospectively analyzed. Of the total cases, 11 cases were diagnosed with cystic IMT with a maximum diameter of 1. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.12.014DOI Listing
March 2019
2 Reads

Diffuse Large B-Cell Lymphoma Arising within Ileal Neobladder: An Expanding Spectrum of Diffuse Large B-Cell Lymphoma Associated with Chronic Inflammation.

Cancer Res Treat 2019 Mar 22. Epub 2019 Mar 22.

Department of Urology, Eulji University Hospital, Daejeon, Korea.

Diffuse large B-cell lymphoma associated with chronic inflammation (DLBCL-CI), specifically arising in ileal neobladder, is a rare neoplasm. We present an unusual case of Epstein-Barr virus (EBV)-positive DLBCL-CI arising within neobladder with detailed clinical, histological, and immunophenotypical features in an immunocompetent patient. An 88-year-old male was admitted for gross hematuria. Read More

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http://www.e-crt.org/journal/view.php?doi=10.4143/crt.2019.0
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http://dx.doi.org/10.4143/crt.2019.022DOI Listing
March 2019
3 Reads

The impact of completeness of last transurethral resection of bladder tumors on the outcomes of radical cystectomy.

World J Urol 2019 Mar 25. Epub 2019 Mar 25.

Klinik für Urologie, Luzerner Kantonsspital, Lucerne, Switzerland.

Purpose: To evaluate the role of a complete transurethral resection of bladder tumors (c-TURBT) on oncological outcomes after radical cystectomy (RC) and its relationship with adverse pathological features.

Methods: We retrospectively analyzed data of 727 patients treated with RC and bilateral pelvic lymph node dissection at three tertiary referral centers. Possible c-TURBT was reported by the treating surgeon. Read More

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http://link.springer.com/10.1007/s00345-019-02734-6
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http://dx.doi.org/10.1007/s00345-019-02734-6DOI Listing
March 2019
4 Reads

Expression and prognostic utility of PD-L1 in patients with squamous cell carcinoma of the bladder.

Urol Oncol 2019 Mar 22. Epub 2019 Mar 22.

Department of Urology, University of California Irvine, Orange, CA. Electronic address:

Objectives: Checkpoint inhibitors are approved for the treatment of urothelial bladder cancer. However, there have been no reports on the prognostic value of programmed-death receptor ligand 1 (PD-L1) expression in squamous cell carcinoma (SCC) of the bladder. We assessed the relationship between PD-L1 expression, clinicopathological features, and oncologic outcomes in bladder SCC. Read More

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http://dx.doi.org/10.1016/j.urolonc.2019.02.017DOI Listing
March 2019
2 Reads

Influence of laparoscopic access in cancer-specific mortality of patients with pTa-2pN0R0 bladder cancer treated with radical cistectomy.

Actas Urol Esp 2019 Mar 22. Epub 2019 Mar 22.

Servicio de Urología, Hospital General Universitario Gregorio Marañón, Madrid, España.

Introduction And Objective: Minimally invasive surgery represents an attractive surgical approach in radical cystectomy. However, its effect on the oncological results is still controversial due to the lack of definite analyses. The objective of this study is to evaluate the effect of the laparoscopic approach on cancer-specific mortality. Read More

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http://dx.doi.org/10.1016/j.acuro.2019.01.001DOI Listing