8,595 results match your criteria Cylindroma


An Early Experience of Microvascular Surgery in a Tertiary Cancer Centre in North East India.

World J Plast Surg 2022 Mar;11(1):148-156

Dept. of Plastic Surgery, Dr B. Borooah Cancer Institute, A Grant-in-Aid Institute of Dept. of Atomic Energy, Govt. of India and a Unit of Tata Memorial Centre-Mumbai. Guwahati, Assam, India.

Background: Microvascular surgery is a highly technique sensitive and evolving speciality in reconstructive oncosurgery. There is a definite learning curve associated with it. In this case series, we describe our initial experience in microvascular surgery at a tertiary cancer centre in North East India. Read More

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Distinct clinicopathological and genomic features in solid and basaloid adenoid cystic carcinoma of the breast.

Sci Rep 2022 May 19;12(1):8504. Epub 2022 May 19.

Department of Pathology, Neijiang First People's Hospital, Neijiang, 641099, Sichuan, China.

Adenoid cystic carcinoma (AdCC) of the breast is a rare indolent carcinoma of salivary gland-type tumors, frequently associated with MYB genetic alteration. Solid and basaloid adenoid cystic carcinoma (SB-AdCC) is considered a sparse variant of AdCC. This study sought to search for clinicopathological and genomic features in SB-AdCC. Read More

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Polarized Microscopic Analysis of Picrosirius Red Stained Salivary Gland Pathologies: An Observational Study.

Eur J Dent 2022 May 17. Epub 2022 May 17.

Department of Anatomy, Faculty of Dentistry, Mahidol University, Bangkok, Thailand.

Objective:  Salivary gland diseases and their pathologies may affect the glandular structure including collagen, a major stromal component, in response to tissue damage or diseases. This study aimed to examine the changes in collagens in different salivary gland diseases using polarized picrosirius red staining.

Materials And Methods:  The submandibular gland samples diagnosed as sialadenitis, chronic sclerosing sialadenitis, pleomorphic adenoma, adenoid cystic carcinoma, and mucoepidermoid carcinoma were stained with picrosirius red, Masson's trichrome, and anticollagen I staining. Read More

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The Role of Advanced Endoscopic Resection of Diverse Skull Base Malignancies: Technological Analysis during an 8-Year Single Institutional Experience.

J Neurol Surg B Skull Base 2021 Aug 5;82(4):417-424. Epub 2020 Aug 5.

Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York City, New York, United States.

 Resection of skull base malignancies poses complex pathological and treatment-related morbidities. Recent technological advancements of endoscopic endonasal surgery (EES) offer the ability to reexamine traditional treatment paradigms with endoscopic procedures. The utility of EES was quantitatively examined in a longitudinal series with attention to morbidities and postoperative outcomes. Read More

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Evaluation of immunohistochemical expression of E-cadherin in pleomorphic adenoma and adenoid cystic carcinoma.

J Oral Maxillofac Pathol 2022 Jan-Mar;26(1):65-71. Epub 2022 Mar 31.

Department of Dentistry, Gayathri Medical College and Hospital, Marikivalasa, Vishakapatnam, Andhra Pradesh, India.

Background: Pleomorphic adenoma (PA) and adenoid cystic carcinoma (ADCC) are benign and malignant salivary gland tumors, respectively, with distinct behavior. They have similar origins and cell components. E-cadherins are the main homophilic cell adhesion molecules, which play a central role in maintaining epithelial integrity, functioning in intercellular adhesion and differentiation. Read More

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Adenoid cystic carcinoma of sinonasal origin masquerading as an intraconal lesion.

BMJ Case Rep 2022 May 13;15(5). Epub 2022 May 13.

Radiodiagnosis, Datta Meghe Institute of Medical Sciences - Wardha Campus, Wardha, Maharashtra, India.

Adenoid cystic carcinoma is an uncommon tumour of the salivary glands, although affliction of mucin-producing glands present in the oral cavity, oropharynx and paranasal sinuses is not uncommon. Other possible sites are lacrimal, oesophagus, trachea-bronchial tree, lungs, uterus, cervix, prostate. These tumours have a tendency to be aggressive and most show invasion into the adjacent region. Read More

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Development and Characterization of MYB-NFIB Fusion Expression in Adenoid Cystic Carcinoma.

Cancers (Basel) 2022 Apr 30;14(9). Epub 2022 Apr 30.

Department of Otolaryngology, Head and Neck Surgery, University of California-San Francisco, Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94080, USA.

Adenoid cystic carcinoma (ACC) is the second most common cancer type arising from the salivary gland. The frequent occurrence of chromosome t(6;9) translocation leading to the fusion of MYB and NFIB transcription factor genes is considered a genetic hallmark of ACC. This inter-chromosomal rearrangement may encode multiple variants of functional MYB-NFIB fusion in ACC. Read More

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Clinical and radiologic outcomes of pleomorphic adenoma and adenoid cystic carcinoma of the lacrimal gland.

Arq Bras Oftalmol 2022 May 9. Epub 2022 May 9.

Department of Ophthalmology, Gazi University School of Medicine, Ankara,Turkey.

Purpose: To compare the radiologic and clinical features of primary lacrimal gland pleomorphic adenoma and adenoid cystic carcinoma.

Methods: This study retrospectively reviewed imaging findings and medical records of lacrimal gland pleomorphic adenoma and adenoid cystic carcinoma.

Results: Eleven patients with pleomorphic adenoma and 16 patients with adenoid cystic carcinoma were evaluated. Read More

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Very long-term survival of a bronchial adenoid cystic-carcinoma treated bronchoscopically.

Respir Med Res 2022 Feb 3;81:100884. Epub 2022 Feb 3.

Thoracic Oncology, Pleural Diseases, and Interventional Pulmonology Department, Hôpital Nord, Assistance Publique-Hôpitaux de Marseille. Chemin des Bourrely, Marseille 13015, France. Electronic address:

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February 2022

Adenoid cystic carcinoma of the prostate - A rare case of genitourinary malignancy.

Urol Case Rep 2022 May 5;42:102025. Epub 2022 Feb 5.

Dept. of Urology, University Hospital Waterford, Dunmore Road, Waterford, X91 ER8E, Ireland.

A 72 year old was referred to the Urology department with lower urinary tract symptoms (LUTS), an abnormal prostate on digital examination and a serum prostate specific antigen (PSA) level within normal limits. A flexible cystoscopy revealed no abnormality of the urethra and an obstructive prostate. Magnetic resonance imaging (MRI) revealed a 4. Read More

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Incidence and trends of cutaneous adnexal tumors in the United States in 2000-2018: A population-based study.

J Am Acad Dermatol 2022 May 4. Epub 2022 May 4.

Department of Dermatology, Emory University School of Medicine, Atlanta, Georgia; Winship Cancer Institute of Emory University School of Medicine, Atlanta, Georgia; Atlanta VA Health Care System, Decatur, Georgia.

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Frequency and imaging features of the adjacent osseous changes of salivary gland carcinomas in the head and neck region.

Neuroradiology 2022 May 7. Epub 2022 May 7.

Department of Diagnostic and Interventional Radiology, Graduate School of Medicine, Osaka Metropolitan University, 1‑4‑3, Asahi‑machi, Abeno‑ku, Osaka, 545‑8585, Japan.

Purpose: The association between salivary gland carcinomas and adjacent osseous changes in the head and neck region is not clear. We evaluated the frequency and imaging features of such changes and investigated the specific characteristics of salivary gland carcinomas associated with them.

Methods: A total of 118 patients with histologically proven salivary gland carcinomas were retrospectively reviewed. Read More

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The anti-tumor effect of proteasome inhibitor MG132 for human adenoid cystic carcinoma: correlate with the emerging role of Nrf2/Keap1 signaling pathway.

Head Face Med 2022 May 6;18(1):15. Epub 2022 May 6.

Department of Oral and Maxillofacial Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, 250021, Jinan, China.

Background: Adenoid cystic carcinoma (ACC) is one of the most common malignant salivary gland tumors. Moreover, the unique biological characteristics and complex structures of ACC contribute to its poor survival rates. Recently, proteasome inhibitors have been shown to elicit satisfactory therapeutic effects in the treatment of certain solid tumors, but few studies have been implemented to investigate the effects of proteasome inhibitor therapy for ACC. Read More

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MYB RNA In Situ Hybridization Is a Useful Diagnostic Tool to Distinguish Breast Adenoid Cystic Carcinoma From Other Triple-negative Breast Carcinomas.

Am J Surg Pathol 2022 May 9. Epub 2022 May 9.

Departments of Pathology.

Breast adenoid cystic carcinoma (AdCC) has overlapping features with basal-like triple-negative breast carcinoma (TNBC), yet carries a more favorable prognosis, and accurate diagnosis is critical. Like salivary gland AdCC, breast AdCC demonstrates recurrent alterations in the MYB gene. Novel chromogenic RNA in situ hybridization (ISH) for MYB has emerged as sensitive and specific for salivary gland AdCC. Read More

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Immunohistochemical Profile of Polymorphous Adenocarcinoma of Minor Salivary Gland: A Systematic Review and Meta-Analysis.

Head Neck Pathol 2022 May 4. Epub 2022 May 4.

Department of Pathology and Translational Pathobiology, Louisiana State University Health Sciences Center, Shreveport, LA, 71103, USA.

Polymorphous adenocarcinoma (PAC) is a rare variant of minor salivary gland tumors. Because of its architectural diversity, histological diagnosis of PAC can be difficult especially for small biopsies, and immunohistochemistry is of great help in differentiating it from its histologic mimics. The aim of this study is to conduct a systematic literature review to identify reliable immunohistochemical markers for PAC. Read More

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Polymorphous Adenocarcinoma: High-Grade Transformation With Immunohistochemical Workup.

Cureus 2022 Mar 30;14(3):e23639. Epub 2022 Mar 30.

Department of Oral and Maxillofacial Pathology, Krishnadevaraya College of Dental Sciences and Hospital, Bangalore, IND.

Intraoral tumours associated with mucosa are commonly oral squamous cell carcinomas followed by minor salivary gland carcinomas, the commonest being mucoepidermoid carcinoma, adenoid cystic carcinoma, and polymorphous adenocarcinoma (PAC). PAC is the second most common malignant tumour that is found in the minor salivary glands of the oral cavity and rarely exhibits high-grade transformation (HGT). We report a case of a 50-year-old woman with a tumour on her buccal mucosa for six months. Read More

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Unexpected recurrence and rapid progression of lacrimal gland adenoid cystic carcinoma during pregnancy: a case report.

Orbit 2022 May 3:1-5. Epub 2022 May 3.

Department of Ophthalmology, Private practice, Rasht, Iran.

Adenoid cystic carcinoma (ACC) is the most common malignant neoplasm involving the lacrimal glands, with high rates of recurrence and metastasis. During the pregnancy, reports of recurrence of ACC of the salivary glands and trachea have previously been published, but no lacrimal gland ACC recurrence has been reported. We present a 35-year-old woman with lacrimal gland ACC who was initially treated by surgical resection and adjunctive radiotherapy, but her cancer recurred during pregnancy, with rapid progression to cavernous sinuses and brain. Read More

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Oncological outcomes of patients with salivary gland cancer treated with surgery and postoperative intensity-modulated radiotherapy: a retrospective cohort study.

Quant Imaging Med Surg 2022 May;12(5):2841-2854

Department of Radiation Oncology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.

Background: Salivary gland cancer (SGC) is relatively rare and constitutes a variety of histological subtypes. Previously published studies of SGC patients suggest that postoperative radiation using conventional radiotherapy (RT) or 3-dimensional (3D) conformal radiotherapy may have led to suboptimal oncological outcomes.

Methods: We identified 60 patients with major SGC treated with surgery followed by postoperative intensity-modulated radiotherapy (IMRT). Read More

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Molecular factors governing perineural invasion in malignancy.

Surg Oncol 2022 Apr 14;42:101770. Epub 2022 Apr 14.

Department of Head and Neck Surgery, Chris O'Brien Lifehouse, Camperdown, Sydney, NSW, Australia; Central Clinical School, Faculty of Medicine and Health, the University of Sydney, Sydney, NSW, Australia; Department of Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, NSW Health Pathology, Camperdown, Sydney, NSW, Australia.

Background: Perinueral invasion (PNI) is recognized as an independent adverse prognostic factor associated with shorter disease free and disease specific survival in a range of malignancies. However, not all histologically detected PNI demonstrate aggressive biologic behaviour. Herein, we systematically review the literature to identify neurotrophic biomarkers that may potentially be used to predict the biologic potential of PNI. Read More

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Cutaneous metastasis of adenoid cystic carcinoma with high-grade transformation: A case presentation.

Kaohsiung J Med Sci 2022 Apr 28. Epub 2022 Apr 28.

Department of Anatomic Pathology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.

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Salivary gland neoplasms with basaloid features in the era of the Milan system for reporting salivary gland cytology: Classification and interobserver agreement.

Diagn Cytopathol 2022 Apr 23. Epub 2022 Apr 23.

Department of Pathology, University of Utah Health Care and ARUP Laboratories, Salt Lake City, Utah, USA.

Background: The Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) has been shown to have moderate to good reproducibility for categorization of salivary gland fine-needle aspiration (FNA) specimens. Less is known of its accuracy and interobserver reproducibility for categorization of the diagnostically difficult group of basaloid neoplasms.

Methods: Forty-five salivary gland specimens with a basaloid morphology (pleomorphic and monomorphic adenomas and adenoid cystic carcinomas) were independently assigned by seven cytopathologists to one of the MSRSGC categories. Read More

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Adenoid cystic carcinoma of the parotid gland: a first case report on C-methionine PET/CT detection of histologically confirmed pulmonary metastases.

Acta Oncol 2022 Apr 22:1-3. Epub 2022 Apr 22.

Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Unità di Medicina Nucleare, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.

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Adenoid cystic carcinoma: A case report and review of literature.

J Oral Maxillofac Pathol 2022 Feb 28;26(Suppl 1):S26-S29. Epub 2022 Feb 28.

Department of General Dentistry, Devmata Hospital, Bhopal, Madhya Pradesh, India.

Adenoid cystic carcinoma (ADCC) is an uncommon tumor of head and neck, whose clinical patterns are characterized by slow growth, perineural invasion and distant metastasis. Cribriform, tubular and solid are the three recognized histopathological patterns which are seen in ADCC. We report a case of ADCC involving palate with an update on the current understanding of its clinical behavior, molecular biology, pathogenesis, histopathological aspect, treatment and prognosis. Read More

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February 2022

Implant Rehabilitation following a partial resection of the Mandible Resulting from Submandibular Gland Malignancy - A Case Report.

J Oral Implantol 2022 Apr 21. Epub 2022 Apr 21.

Resident, Post-Graduate Prosthodontics, Nova Southeastern University College of Dental Medicine.

Adenoid cystic carcinoma of the submandibular gland is a relatively rare malignancy of the oral and maxillofacial region.  It is an insidious disease characterized by regional spread, perineural invasion, and potential distant metastases.  Because of the aggressive nature of this lesion, it is often impossible to completely excise the tumor, necessitating combination therapy of surgery and radiation. Read More

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Primary cutaneous adenoid cystic carcinoma - An onerous task for clinicians and pathologists.

Indian J Pathol Microbiol 2022 Apr-Jun;65(2):459-461

Department of Pathoogy, Navodaya Medical College, Raichur, Karnataka, India.

Adenoid cystic carcinoma (ACC) is an uncommon malignant neoplasm usually confined to the salivary glands, lungs, and breasts. Primary cutaneous adenoid cystic carcinoma (PCACC) is an extremely rare entity with solitary cases reported at sites away from the scalp and chest. Hence, one must follow the multidisciplinary approach to exclude any primary ACC elsewhere in the body. Read More

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Hyalinizing Clear Cell Salivary Gland Carcinoma of the Epipharynx: A Minor Salivary/Tubarial Gland Malignancy.

Biomed Hub 2022 25;7(1):31-35. Epub 2022 Feb 25.

Department of Otolaryngology, Kantonsspital Aarau AG, Aarau, Switzerland.

Minor salivary gland malignancies are a rare entity among head and neck tumors. As in major gland neoplasms, adenoid cystic carcinoma and mucoepidermoid carcinoma are the most common histological subtypes. Malignant tumors affecting minor salivary glands include a wide range of histopathologic types. Read More

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February 2022

Adenoid Cystic Carcinoma with Intracranial Extension.

Arch Iran Med 2022 Mar 1;25(3):191-193. Epub 2022 Mar 1.

Department of Oral and Maxillofacial Pathology, School of Dentistry, Birjand University of Medical Sciences, Birjand, Iran.

Adenoid cystic carcinoma (ADCC) is a malignant tumor of salivary gland origin. ADCC of sinonasal tract is rare. We present a rare and unresectable case of sinonasal ADCC with intracranial extension in an 83-year-old man with the chief complaint of nasal congestion. Read More

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Management of malignant submandibular gland tumors: A 30-year experience from a single center.

Oral Surg Oral Med Oral Pathol Oral Radiol 2022 Feb 4. Epub 2022 Feb 4.

Division of Radiation Oncology, Department of Radiotherapy and Medical Oncology, University Hospital for Tumors, University Hospital Center "Sisters of Mercy", Zagreb, Croatia.

Objective: Owing to histologic heterogeneity, biological behavior, and rarity, recommendations for the treatment of malignant submandibular gland tumors (MSGT) are inconsistent. The aim of this study was to present a single-center experience in the treatment of MSGT with an emphasis on surgical treatment, including indication on elective neck dissection (END).

Study Design: Twenty-four MSGT were primary surgically treated (gland excision with neck dissection). Read More

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February 2022

The rate of occult nodal metastasis in submandibular gland malignancies: A case series and meta-analysis.

Oral Surg Oral Med Oral Pathol Oral Radiol 2022 Feb 23. Epub 2022 Feb 23.

Department of Otolaryngology, Head and Neck Surgery and Maxillofacial Surgery, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel.

Objective: Submandibular gland (SMG) malignancies are exceedingly rare. Lymph node metastasis is one of the most important determinants of outcome in SMG malignancies. The aim of this study was to investigate the overall rate of occult neck nodal metastasis in SMG malignancies. Read More

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February 2022

Correction: Endoscopic submucosal dissection of poorly differentiated carcinoma mimicking adenoid-cystic carcinoma of the esophagus.

Endoscopy 2022 Apr 14. Epub 2022 Apr 14.

Gastroenterology Unit, Azienda Unità Sanitaria Locale della Romagna, Santa Maria delle Croci Hospital, Ravenna, Italy.

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