7,608 results match your criteria Cylindroma


Application of diffusion-weighted MR imaging with ADC measurement for distinguishing between the histopathological types of sinonasal neoplasms.

Clin Imaging 2019 Feb 7;55:76-82. Epub 2019 Feb 7.

Department of Radiology, University of Minnesota Medical Center, Minneapolis, MN, USA. Electronic address:

Purpose: To evaluate the potential contribution of quantitative DWI parameters including ADC and ADC values to help in distinguishing the histopathological types of sinonasal neoplasms.

Methods: This retrospective study included 83 patients (50 males, 33 females; mean age 61 years) with pathologically proven untreated sinonasal neoplasms who have undergone diffusion-weighted MRI imaging from February 2010 to August 2017. Diffusion-weighted MRI was performed on a 3 T unit with b factors of 0 and 1000 s/mm, and ADC maps were generated. Read More

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http://dx.doi.org/10.1016/j.clinimag.2019.02.004DOI Listing
February 2019

Serial patient-derived orthotopic xenografting of adenoid cystic carcinomas recapitulates stable expression of phenotypic alterations and innervation.

EBioMedicine 2019 Feb 11. Epub 2019 Feb 11.

University of Michigan, Biointerfaces Institute, Ann Arbor, MI, United States; University of Michigan, School of Dentistry, Department of Biologic and Materials Sciences, Ann Arbor, MI, United States. Electronic address:

Background: Patient-derived xenograft (PDX) models have significantly enhanced cancer research, and often serve as a robust model. However, enhanced growth rate and altered pathological phenotype with serial passages have repeatedly been shown in adenoid cystic carcinoma (ACC) PDX tumors, which is a major concern.

Methods: We evaluated the fidelity of ACCs in their natural habitat by performing ACC orthotopic xenotransplantation (PDOX) in salivary glands. Read More

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http://dx.doi.org/10.1016/j.ebiom.2019.02.011DOI Listing
February 2019

The value of MYB as a prognostic marker for adenoid cystic carcinoma: A meta-analysis.

Head Neck 2019 Feb 13. Epub 2019 Feb 13.

Department of Oral and Maxillofacial Surgery, Guanghua School of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Sun Yat-Sen University, Guangzhou, Guangdong, China.

The aim of this meta-analysis is to evaluate myeloblastosis (MYB) as a prognostic marker for patients with adenoid cystic carcinoma (ACC) with respect to MYB gene fusion, MYB protein expression, and tumor sites. We comprehensively searched PubMed, Embase, Web of Science, and Cochrane libraries. Ten studies concerning the prognostic comparisons between MYB positivity and negativity were included. Read More

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http://dx.doi.org/10.1002/hed.25597DOI Listing
February 2019
1 Read

Autophagy-related Gene Expression Regulated by HIF-1α in Salivary Adenoid Cystic Carcinoma.

Oral Dis 2019 Feb 11. Epub 2019 Feb 11.

Department of Oral and Maxillofacial Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, 250012, China.

Objectives: Salivary adenoid cystic carcinoma (SACC) is one of the most common malignant salivary gland tumors. Our study aims to investigate whether hypoxia-induced autophagy was up-regulated in the progression of SACC.

Materials And Methods: We performed differentially expressed gene analysis, pathway enrichment analysis and then calculated the correlation analysis on GSE59701 and GSE28996 datasets. Read More

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http://dx.doi.org/10.1111/odi.13058DOI Listing
February 2019

CT features and differential diagnosis of primary pulmonary mucoepidermoid carcinoma and pulmonary adenoid cystic carcinoma.

J Thorac Dis 2018 Dec;10(12):6501-6508

Department of Radiology, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510120, China.

Background: The differential diagnosis of primary pulmonary mucoepidermoid carcinoma (PMEC) and pulmonary adenoid cystic carcinoma (PACC) is difficult, because both tumors could be similar in terms of certain characteristics on CT.

Methods: The CT findings from 24 cases of PMEC and 30 cases of PACC were retrospectively analyzed. According to the position of the lesion in airway, we divided these cases into three types: central, hilar, and peripheral. Read More

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http://dx.doi.org/10.21037/jtd.2018.11.71DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344748PMC
December 2018

Pretreatment assessment of hematologic and inflammatory markers in adenoid cystic carcinoma: neutrophil/lymphocyte ratio is associated with multiple recurrences.

Oral Surg Oral Med Oral Pathol Oral Radiol 2018 Oct 30. Epub 2018 Oct 30.

Department of Otorhinolaryngology, Medical University of Vienna, Vienna, Austria.

Objective: Adenoid cystic carcinoma (ACC) is a rare entity of salivary gland cancer. Inflammatory and hematologic markers and their prognostic and predictive value have been intensively studied in several cancer entities. The aim of this study was to investigate the role of such markers in patients with ACC. Read More

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http://dx.doi.org/10.1016/j.oooo.2018.10.009DOI Listing
October 2018
1 Read

More than meets the eye.

BMJ Case Rep 2019 Feb 7;12(2). Epub 2019 Feb 7.

Department of Otolaryngology Head and Neck Surgery, St. James's Hospital, Dublin, Ireland.

We report an extremely rare case of a hybrid tumour of the maxillary sinus. A 51-year-old man presented with a 6-week history of nasal congestion and epiphora. Radiological imaging demonstrated a maxillary sinus tumour, with extensive local invasion. Read More

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http://dx.doi.org/10.1136/bcr-2015-212000DOI Listing
February 2019

Role of apoptotic, autophagic and senescence pathways in minor salivary gland adenoid cystic carcinoma.

Diagn Pathol 2019 Feb 8;14(1):14. Epub 2019 Feb 8.

Department of Oral Pathology, São Leopoldo Mandic Research Institute, Rua José Rocha Junqueira, 13, CEP, Campinas, SP, 13045-610, Brazil.

Background: Adenoid cystic carcinoma (ACC) is a salivary gland malignancy with poor long-term survival, which warrants studies aimed at clarifying the pathogenesis of this disease in order to widen the scope of therapeutic options currently available. Alterations in regulatory mechanisms relating to vascular support, cell death and autophagy are important pathways for tumor growth in cancer. Thus, the present study aimed to access vascular supply, apoptosis, autophagy and cell senescence in ACC of minor salivary glands. Read More

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http://dx.doi.org/10.1186/s13000-019-0796-2DOI Listing
February 2019

CXCR4 and PD-1 Expression in Head and Neck Cancer with Perineural Spread.

J Neurol Surg B Skull Base 2019 Feb 14;80(1):18-22. Epub 2018 Jun 14.

School of Medicine, University of Queensland, Brisbane, Queensland, Australia.

 Perineural spread (PNS) is a marker of aggressiveness and has been shown to occur in cranial nerves due to advanced mucosal and cutaneous head and neck cancer. Receptors CXC chemokine receptor 4 (CXCR4) and programmed cell death-1 (PD-1) have been shown to be overexpressed in a variety of cancers with PNS, with the inhibition of these pathways offering a potential future treatment.  Retrospective immunohistochemical staining for the CXCR4 and PD-1 receptors was performed on 28 head and neck specimens that demonstrated PNS from January 2017 to August 2017, at Royal Brisbane and Women's Hospital, Brisbane, Australia. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1660846
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http://dx.doi.org/10.1055/s-0038-1660846DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365291PMC
February 2019
2 Reads

Personalized Treatment for Lacrimal Sac Adenoid Cystic Carcinoma - Case Report and Literature Review.

Pract Radiat Oncol 2019 Feb 4. Epub 2019 Feb 4.

Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, WI.

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http://dx.doi.org/10.1016/j.prro.2019.01.011DOI Listing
February 2019

Fibroblast growth factor receptor 1 (FGFR1) as a therapeutic target in adenoid cystic carcinoma of the lacrimal gland.

Oncotarget 2019 Jan 11;10(4):480-493. Epub 2019 Jan 11.

Dr. Nasser Al-Rashid Orbital Vision Research Center, Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.

Identification of molecular targets is the first step in developing efficacious therapeutic strategies for tumors. A tumors' biological response to perturbagens yields important information on the molecular determinants for tumor growth. The aim of this study was to characterize the response of adenoid cystic carcinoma of the lacrimal gland (LGACC) to intra-arterial cytoreductive chemotherapy (IACC) in order to identify novel targets to enhance therapy. Read More

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http://dx.doi.org/10.18632/oncotarget.26558DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355187PMC
January 2019

The role of organ- and function-preserving radiotherapy in the treatment of adenoid cystic carcinoma of the larynx.

Head Neck 2019 Feb 5. Epub 2019 Feb 5.

Department of Radiation Oncology, University Hospital Heidelberg, Heidelberg, Germany.

Background: To evaluate clinical outcome and functional larynx preservation after radiotherapy (RT) for adenoid cystic carcinoma (ACC) of the larynx.

Methods: Eleven patients with primary ACC of the larynx, who received RT definitely (n = 5/11) or postoperatively (n = 6/11), were analyzed regarding survival and treatment-related toxicity with the focus on functional larynx preservation.

Results: Median follow-up was 45 months. Read More

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http://dx.doi.org/10.1002/hed.25678DOI Listing
February 2019
1 Read

Polymorphous adenocarcinoma of the salivary glands: An overview of immunohistochemical features and insights on molecular pathology.

Histol Histopathol 2019 Feb 6:18089. Epub 2019 Feb 6.

First Department of Pathology, Medical School, National and Kapodistrian University of Athens, Athens, Greece.

Polymorphous adenocarcinoma (PAC), represents a common minor salivary gland tumor (SGT) characterized by local growth, low metastatic potential and non-aggressive biologic behavior. Due to the clinical aggressiveness noted in a subset of such tumors, the former term polymorphous low-grade adenocarcinoma (PLGA) was recently revised. PAC's clinical features and histological diversity result in clinical overlap of this entity with several other SGTs including mainly adenoid cystic carcinoma (AdCC). Read More

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http://dx.doi.org/10.14670/HH-18-089DOI Listing
February 2019

Adenoid Cystic Carcinoma of Buccal Mucosa: Role of F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in the Detection and Biopsy of Pulmonary Metastases and Assessment of Treatment Response.

Indian J Nucl Med 2019 Jan-Mar;34(1):71-73

Department of Radiotherapy, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Adenoid cystic carcinoma of the buccal mucosa has an increased propensity for recurrence and distant metastases. Due to the poor prognosis at late detection of distant metastases, it is advisable to keep a close follow-up. In the present case, F-fluorodeoxyglucose positron emission tomography/computed tomography proved invaluable in the comprehensive workup of the patient, including detection of local recurrence, distant metastases, and in assessing treatment response. Read More

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http://dx.doi.org/10.4103/ijnm.IJNM_80_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352631PMC
February 2019

Computed tomographic features of adenoid cystic carcinoma in the palate.

Cancer Imaging 2019 Jan 31;19(1). Epub 2019 Jan 31.

Department of Oral and Maxillofacial-Head and Neck Oncology, Ninth Peoples Hospital, College of Stomatology Shanghai Jiao Tong University School of Medicine, No. 639 Zhizaoju Road, Shanghai, 200011, China.

Background: To evaluate the computed tomographic features and create a prediction model for clinical diagnosis of adenoid cystic carcinoma (ACC) in the palate with intact mucosa.

Methods: From March 2016 to May 2018, 102 patients with palatal tumors and intact mucosa, including 28 patients with a pathological diagnosis of ACC after surgery, were enrolled in this study. The patients' clinical symptoms, computed tomographic features and pathological diagnoses were recorded and analyzed. Read More

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https://cancerimagingjournal.biomedcentral.com/articles/10.1
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http://dx.doi.org/10.1186/s40644-019-0190-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357373PMC
January 2019
3 Reads

Adenoid cystic carcinoma of the breast.

J Surg Case Rep 2019 Jan 24;2019(1):rjy355. Epub 2019 Jan 24.

Department of Pathology, The Brooklyn Hospital Center, Brooklyn, NY 11201, USA.

Adenoid cystic carcinoma of the breast (ACC) is a rare tumor, comprising <0.1% of all breast cancers. It has a unique dual-cell pattern and is indistinguishable from ACC arising from salivary tissue. Read More

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https://academic.oup.com/jscr/article/doi/10.1093/jscr/rjy35
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http://dx.doi.org/10.1093/jscr/rjy355DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344919PMC
January 2019
5 Reads

A microRNA signature for the differential diagnosis of salivary gland tumors.

PLoS One 2019 25;14(1):e0210968. Epub 2019 Jan 25.

Department of Surgical Pathology, Medical, Molecular and Critical Area, University of Pisa, Pisa, Italy.

Salivary gland tumors (SGTs) are rare tumors of the head and neck with different clinical behavior. Preoperative diagnosis, based on instrumental and cytologic examinations, is crucial for their correct management. The identification of molecular markers might improve the accuracy of pre-surgical diagnosis helping to plan the proper treatment especially when a definitive diagnosis based only on cytomorphology cannot be achieved. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0210968PLOS
January 2019
1 Read

Hsa_circRNA_0059655 plays a role in salivary adenoid cystic carcinoma by functioning as a sponge of miR-338-3p.

Cell Mol Biol (Noisy-le-grand) 2018 Dec 31;64(15):100-106. Epub 2018 Dec 31.

Central Laboratory, Peking University School and Hospital of Stomatology& National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology &Beijing Key Laboratory of Digital Stomatology, Beijing, 10081, China.

Circular RNAs(circRNA) are recently demonstrated to have a close relationship with tumors.To investigate the role of circular RNA in the pathogenesis of salivary adenoid cystic carcinoma(SACC), ten SACC tissues and paired normal submandibular gland(SMG) tissues were collected as the tumor group and the control group. Total RNA was extracted and then measured using ceRNA microarray (including mRNA, lncRNA, and circRNA) and miRNA microarray. Read More

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December 2018
5 Reads

MIF promotes perineural invasion through EMT in salivary adenoid cystic carcinoma.

Mol Carcinog 2019 Jan 22. Epub 2019 Jan 22.

State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, No.14, Sec. 3, Renminnan Road, Chengdu Sichuan 610041, China.

Macrophage migration inhibitory factor (MIF) is a prominent orchestrator during the onset and progression of cancer. Recently, MIF was detected in salivary adenoid cystic carcinoma (SACC). However, its functional effect in perineural invasion (PNI) of SACC remained unknown. Read More

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http://dx.doi.org/10.1002/mc.22979DOI Listing
January 2019
1 Read
4.808 Impact Factor

The Role of Elective Neck Dissection in Patients With Adenoid Cystic Carcinoma of the Head and Neck.

Laryngoscope 2019 Jan 22. Epub 2019 Jan 22.

Department of Otolaryngology, Harvard Medical School; Massachusetts Eye and Ear, Boston, Massachusetts, U.S.A.

Objective: To investigate the frequency and outcomes of elective neck dissection (END) for adenoid cystic carcinoma (ACC) of the head and neck.

Methods: The National Cancer Database was queried for a cohort study of patients with ACC of the major salivary glands, nasal cavity/nasopharynx, hard/soft palate, tongue, floor of mouth, larynx, and oral cavity who underwent primary surgical resection from 2004 to 2014. Multivariable logistic regression was used to identify predictors of END and occult nodal metastasis. Read More

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http://doi.wiley.com/10.1002/lary.27814
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http://dx.doi.org/10.1002/lary.27814DOI Listing
January 2019
5 Reads

Basal cell carcinoma of the prostate: A case report and review of the literature.

Mol Clin Oncol 2019 Jan 30;10(1):101-104. Epub 2018 Oct 30.

Department of Urology, Nankai Medical Center, Saiki, Oita 876-0857, Japan.

Basal cell carcinoma (BCC) of the prostate is a rare tumor exhibiting various morphological characteristics, and its progression varies from an indolent to an aggressive type, with local recurrence or distant metastasis. We herein report the case of a patient who was diagnosed with early-stage BCC of the prostate and treated by surgery. A 68 year-old-man visited our hospital for a follow-up for bladder cancer. Read More

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http://dx.doi.org/10.3892/mco.2018.1754DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313957PMC
January 2019
1 Read

Contemporary treatment patterns and outcomes of salivary gland carcinoma: a National Cancer Database review.

Eur Arch Otorhinolaryngol 2019 Jan 16. Epub 2019 Jan 16.

Department of Otolaryngology-Head and Neck Surgery, Oregon Health and Science University, 3181 SW Sam Jackson Park Rd, Portland, OR, 97239, USA.

Purpose: Salivary gland carcinomas (SGC) are rare malignancies and data regarding treatment outcomes stratified by histologic subtype are currently limited. This study aims to examine current, national treatment patterns and overall survival (OS) of patients with the major histologic subtypes of salivary gland carcinoma.

Subjects And Methods: A review was performed of the National Cancer Database (NCDB) of patients with confirmed diagnoses of mucoepidermoid carcinoma, acinic cell carcinoma, adenoid cystic carcinoma, adenocarcinoma, or carcinoma ex pleomorphic receiving curative treatment between 2004 and 2014. Read More

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http://link.springer.com/10.1007/s00405-019-05282-2
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http://dx.doi.org/10.1007/s00405-019-05282-2DOI Listing
January 2019
6 Reads

Adenoid cystic carcinoma of the sinonasal tract: a review of the national cancer database.

Int Forum Allergy Rhinol 2019 Jan 15. Epub 2019 Jan 15.

Department of Otorhinolaryngology-Head and Neck Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.

Background: Sinonasal adenoid cystic carcinoma (SNACC) is a rare malignancy with a propensity for distant metastasis. In this study we describe the incidence and determinants of survival among patients with SNACC between the years 2004 and 2012 using the National Cancer Database (NCDB).

Methods: This was a retrospective, population-based cohort study performed at a tertiary academic medical center. Read More

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http://dx.doi.org/10.1002/alr.22255DOI Listing
January 2019
9 Reads

Lack of Deletion of 1p36 in 8 Cases of Primary Adenoid Cystic Carcinoma of the Skin.

Am J Dermatopathol 2019 Jan 11. Epub 2019 Jan 11.

Sikl's Department of Pathology, Medical Faculty in Pilsen, Charles University in Prague, Pilsen, Czech Republic.

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http://dx.doi.org/10.1097/DAD.0000000000001294DOI Listing
January 2019
1 Read

[Clinical pathologic analysis on 3 724 cases of salivary gland tumors].

Zhonghua Kou Qiang Yi Xue Za Zhi 2019 Jan;54(1):10-16

Department of Pathology, Hospital of Stomatology, Jilin University, Changchun 130021, China.

To investigate the incidence and proportion of salivary gland tumors in order to provide new thinking for clinical diagnosis and treatment. Collected 3 724 cases salivary gland tumors diagnosed by Pathology Department of Hospital of Stomatology, Jilin University from January 1961 to December 2016. The pathological diagnosis referred to the fourth edition of head and neck-salivary gland tumor histopathological classification standard of WHO. Read More

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http://dx.doi.org/10.3760/cma.j.issn.1002-0098.2019.01.003DOI Listing
January 2019
2 Reads

Successful management of recurrent adenoid cystic carcinoma in the deep infratemporal fossa by maxillo-orbito-zygomatic approach.

Auris Nasus Larynx 2019 Jan 6. Epub 2019 Jan 6.

Department of Head and Neck Surgery. Electronic address:

Objective: In the case of deep invasion of an infratemporal fossa (ITF) tumor, surgeons find it difficult to gain sufficient visualization and working space by conventional surgical approaches. To overcome these limitations, we have developed a novel surgical technique, maxillo-orbito-zygomatic (MOZ) approach, by combining partial lateral maxillectomy with the conventional orbito-zygomatic approach.

Methods: A 63-year-old male presented with the fifth recurrent adenoid-cystic carcinoma in the right deep ITF. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03858146183026
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http://dx.doi.org/10.1016/j.anl.2018.12.010DOI Listing
January 2019
2 Reads

Impact of lymph node sampling on survival in cN0 major salivary gland adenoid cystic carcinoma.

Head Neck 2019 Jan 8. Epub 2019 Jan 8.

Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine, Stanford, California.

Background: The role of elective neck dissection in the management of major salivary gland adenoid cystic carcinoma is unclear.

Methods: Data were retrospectively extracted from the National Cancer Center Database. The study cohort included 1504 patients with adenoid cystic carcinoma of major salivary glands with clinical N0 necks who were treated with surgery between 2004 and 2014. Read More

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http://dx.doi.org/10.1002/hed.25628DOI Listing
January 2019
1 Read

Immune microenvironment and evasion mechanisms in adenoid cystic carcinomas of salivary glands.

Oral Oncol 2019 Jan 23;88:95-101. Epub 2018 Nov 23.

Department of Stomatology (Oral Pathology), School of Dentistry, Universidade Federal de Goiás, Goiânia, GO, Brazil. Electronic address:

Objectives: The objective of the present study was to investigate the expression of immune checkpoints (PD-L1, PD-L2, PD-1 and CTLA-4), immune inhibitory molecule HLA-G, markers of tumor-infiltrating lymphocytes (TIL) and dendritic cells (DC), as well as its association with clinicopathological features of adenoid cystic carcinomas (ACC) of the salivary glands.

Materials And Methods: Thirty-six samples from patients with ACC were analyzed immunohistochemically for the expression of PD-L1, PD-L2, PD-1, CTLA-4, HLA-G, CD8, GrB, CD1a and CD83. Positivity of HLA-G, PD-L1 and PD-L2 expression was defined by cut-offs values. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13688375183044
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http://dx.doi.org/10.1016/j.oraloncology.2018.11.028DOI Listing
January 2019
5 Reads

The efficacy of neutron radiation therapy in treating salivary gland malignancies.

Oral Oncol 2019 Jan 21;88:51-57. Epub 2018 Nov 21.

Department of Oral and Maxillofacial Surgery, Harborview Medical Center, University of Washington, USA. Electronic address:

Objectives: Radiation therapy is commonly used to treat head and neck malignancies. While there is abundant research regarding photon radiation therapy, literature on neutron radiotherapy (NRT) and oral complications is limited. This study aims to determine: (1) the 6-year and 10-year locoregional control and survival rates, (2) factors associated with locoregional control and survival and (3) the frequency of oral complications in patients undergoing NRT for salivary gland malignancies. Read More

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http://dx.doi.org/10.1016/j.oraloncology.2018.11.006DOI Listing
January 2019

What are the multimode sonographic features of adenoid cystic carcinoma metastasized to the thyroid?

Chin Med J (Engl) 2019 Jan;132(2):247-249

Department of Ultrasonography, West China Hospital of Sichuan University, Chengdu, Sichuan 610000, China.

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http://dx.doi.org/10.1097/CM9.0000000000000033DOI Listing
January 2019
2 Reads

Adenoid cystic carcinoma of the vagina: A case report.

Medicine (Baltimore) 2019 Jan;98(1):e13852

Department of Pathology, West China Second University Hospital, Sichuan University.

Rationale: Squamous carcinoma is the most common malignancy of vagina. Adenoid cystic carcinoma (ACC) in the vagina is very rare.

Patient Concerns: In the present study, we present a 45-year-old woman with a palpable swelling in the vagina. Read More

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http://dx.doi.org/10.1097/MD.0000000000013852DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344208PMC
January 2019
1 Read

Recurrence of Ventral Skull Base Lesions Attributed to Tumor Seeding: A Systematic Review.

World Neurosurg 2018 Dec 31. Epub 2018 Dec 31.

Department of Otolaryngology, William Beaumont Hospital, Royal Oak, Michigan, USA; Barbara Ann Karmanos Cancer Institute, Detroit, Michigan, USA.

Objective: To evaluate ventral skull base lesion recurrences along surgical access pathways attributed to iatrogenic seeding.

Methods: A systematic review of the literature was performed searching for recurrence of ventral skull base lesions attributed to iatrogenic implantation. Studies were assessed for level of evidence. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183292
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http://dx.doi.org/10.1016/j.wneu.2018.12.104DOI Listing
December 2018
11 Reads

c-MYB and DMTF1 in Cancer.

Cancer Invest 2019 Jan 2:1-20. Epub 2019 Jan 2.

a The Department of Pathology , Wake Forest University School of Medicine , Winston-Salem , NC , USA.

The c-Myb gene encodes a transcription factor that regulates cell proliferation, differentiation, and apoptosis through protein-protein interaction and transcriptional regulation of signaling pathways. The protein is frequently overexpressed in human leukemias, breast cancers, and other solid tumors suggesting that it is a bona fide oncogene. c-MYB is often overexpressed by translocation in human tumors with t(6;7)(q23;q34) resulting in c-MYB-TCRβ in T cell ALL, t(X;6)(p11;q23) with c-MYB-GATA1 in acute basophilic leukemia, and t(6;9)(q22-23;p23-24) with c-MYB-NF1B in adenoid cystic carcinoma. Read More

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http://dx.doi.org/10.1080/07357907.2018.1550090DOI Listing
January 2019
1 Read

Primary Adenoid Cystic Carcinoma of the Liver: Case Report and Review of the Literature.

Ann Hepatol 2018 Dec;18(1):209-214

Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO, USA.

Adenoid cystic carcinoma (ACC) is an uncommon tumor primarily occurring in the salivary glands and is relatively rare in other sites. In the liver, only one primary adenoid cystic carcinoma has been reported in the English literature. Here we presented a primary hepatic adenoid cystic carcinoma in a 44 years old male. Read More

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http://dx.doi.org/10.5604/01.3001.0012.7915DOI Listing
December 2018
1 Read

Change of Circulating and Tissue-Based miR-20a in Human Cancers and Associated Prognostic Implication: A Systematic Review and Meta-Analysis.

Biomed Res Int 2018 25;2018:6124927. Epub 2018 Nov 25.

Centre for Osteonecrosis and Joint-Preserving & Reconstruction, Orthopaedic Department, China-Japan Friendship Hospital, Chaoyang District, Beijing, China.

Background: Previous literatures have investigated the change of miR-20a expression level in the progression of multiple cancers and its influence on patients' survival outcome, but results of now-available evidence are inconsistent.

Objective: To elucidate the prognostic value of circulating and tissue-based miR-20a for patients with various cancers.

Methods: A systematic search and review of eligible publications were carried out in three electronic databases including the Cochrane Library, PubMed, and Embase, and the methodological quality of included studies was assessed according to Newcastle-Ottawa Scale (NOS). Read More

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http://dx.doi.org/10.1155/2018/6124927DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286746PMC
November 2018
6 Reads

A rare case of nasopharyngeal adenoid cystic carcinoma treated with cetuximab-based induction therapy followed by concurrent chemoradiotherapy.

Oral Oncol 2019 Feb 26;89:161-163. Epub 2018 Dec 26.

Department of E.N.T, Second Clinical Medicine College of Jinan University, Shenzhen People's Hospital, China.

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http://dx.doi.org/10.1016/j.oraloncology.2018.12.022DOI Listing
February 2019

Clinicopathological and Molecular Characteristics of Mammary Adenoid Cystic Carcinoma With Adipocytic Differentiation With Emphasis on the Identification of a Novel Mutation.

Anticancer Res 2019 Jan;39(1):369-374

Department of Pathology and Translational Genomics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea

Background/aim: Adenoid cystic carcinoma accounts for fewer than 1% of all breast malignancies. Herein, we describe the clinicopathological characteristics and immunophenotype of mammary adenoid cystic carcinoma that exhibited adipocytic differentiation. Furthermore, we aimed to identify mutations potentially associated with this rare tumor. Read More

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http://ar.iiarjournals.org/lookup/doi/10.21873/anticanres.13
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http://dx.doi.org/10.21873/anticanres.13121DOI Listing
January 2019
5 Reads

Review of 109 cases of primary malignant orofacial lesions seen at a Nigerian Tertiary Hospital.

Niger Postgrad Med J 2018 Oct-Dec;25(4):246-251

Department of Oral and Maxillofacial Surgery/Oral Pathology, Obafemi Awolowo University, Ile-Ife, Nigeria.

Background: Orofacial malignancy is a growing health issue common in developing regions of the world. Presentation patterns are myriad with geographic variations. Advanced stage owing to late presentation constitutes a significant public health burden. Read More

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http://dx.doi.org/10.4103/npmj.npmj_115_18DOI Listing
December 2018
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Distinctive clinicopathological features and disease‑specific survival of adenoid cystic carcinoma and adenoid basal carcinoma in the lower female genital tract.

Oncol Rep 2019 Mar 12;41(3):1769-1778. Epub 2018 Dec 12.

Department of Epidemiology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.

Adenoid cystic carcinomas (ACCs) and adenoid basal carcinomas (ABCs) in the lower female genital tract are very rare. Data on the clinicopathologic features and survival outcomes of ACCs and ABCs in the lower female genital tract are limited to case reports and small case series studies. The present study systemically analyzed 233 cases, including 84 cervical ACCs, 78 cervical ABCs and 71 vulvar ACCs, to identify clinicopathologic features and survival factors in a population‑based Surveillance, Epidemiology and End Results (SEER) study. Read More

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http://dx.doi.org/10.3892/or.2018.6927DOI Listing

PTEN downregulates WD repeat‑containing protein 66 in salivary adenoid cystic carcinoma.

Oncol Rep 2019 Mar 13;41(3):1827-1836. Epub 2018 Dec 13.

Department of Oral Pathology, Dental School, Dalian Medical University, Dalian, Liaoning 116044, P.R. China.

Salivary adenoid cystic carcinoma (SACC) is one of the most common types of salivary gland cancer that causes substantial morbidity and mortality. Despite the substantial health burden of SACC, the molecular mechanisms underlying its development and progression remain poorly understood. We previously reported the loss of phosphatase and tensin homolog (PTEN) expression to be common among SACC tumors, and the PTEN deficiency to be correlated with enrichment of epithelial‑mesenchymal transition (EMT) genes based on expression array analysis. Read More

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http://www.spandidos-publications.com/10.3892/or.2018.6931
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http://dx.doi.org/10.3892/or.2018.6931DOI Listing
March 2019
14 Reads

Solitary pulmonary metastasis from a gingival cancer of 36 years ago: A case report.

Int J Surg Case Rep 2018 24;53:436-440. Epub 2018 Nov 24.

Departments of General Thoracic Surgery, Seirei Hamamatsu General Hospital, Japan.

Introduction: Unlike a squamous cell carcinoma (SqCC), an adenoid cystic carcinoma (ACC) is an uncommon histology of all head and neck cancers. The clinical significance of a pulmonary metastasectomy differs greatly between these two types of cancers. A solitary pulmonary nodule in a patient with a history of both these different malignancies is a diagnostic and therapeutic challenge. Read More

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http://dx.doi.org/10.1016/j.ijscr.2018.11.053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262786PMC
November 2018
1 Read

[Treatment Options for Adenoid Cystic Lacrimal Gland Carcinoma - A Case Series and Literature Review].

Klin Monbl Augenheilkd 2019 Jan 19;236(1):35-38. Epub 2018 Dec 19.

Klinik für Augenheilkunde, Universitätsklinikum Münster, Münster.

Adenoid cystic carcinoma of the lacrimal gland (ACC) is a rare malignant orbital tumour with a poor overall prognosis. Current therapeutic approaches like radical and local surgery, adjuvant radiation and neoadjuvant intra-arterial chemotherapy are controversial. We present three cases of patients with ACC with different therapy concepts and discuss these with current recommendations from the literature. Read More

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http://dx.doi.org/10.1055/a-0770-3666DOI Listing
January 2019

Adenoid cystic carcinoma in ventricle of larynx: An interesting case.

Medicine (Baltimore) 2018 Dec;97(50):e13622

Department of Otolaryngology, First Affiliated Hospital, College of Medicine, Zhe Jiang University, Hangzhou.

Rationale: Adenoid cystic carcinomas (ACCs) are malignant tumors and occur in the major and the minor salivary glands. ACCs are rare in the larynx.

Patient Concerns: A 55-year-old female patient who presented with a 12 months history of paraesthesia pharynges and hoarseness for 4 months. Read More

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http://dx.doi.org/10.1097/MD.0000000000013622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320204PMC
December 2018
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29-year-old with dyspareunia and vulvar mass: An unusual diagnosis of Bartholin's gland carcinoma.

Gynecol Oncol Rep 2019 Feb 16;27:15-18. Epub 2018 Nov 16.

University of Cincinnati Medical Center, 234 Goodman St, Cincinnati, OH 45220, United States.

•Bartholin's gland carcinoma, adenoid cystic subtype, can occur in younger patients.•These cancers are at high risk of local recurrence and surveillance is needed.•There remains limited evidence specific to these cancers. Read More

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http://dx.doi.org/10.1016/j.gore.2018.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280628PMC
February 2019

Sleeve pneumonectomy and carinal resection for management of primary adenoid cystic tumor of the lung with carinal extension: Report of two cases.

Respir Med Case Rep 2019 24;26:82-86. Epub 2018 Nov 24.

Thoracic Surgery Service, Biomedical Research in Thorax, Fundación Valle del Lili, Universidad Icesi, Cali, Colombia.

Adenoid cystic carcinoma is a rare tumor of low frequency, low grade malignancy and slow growth originating from the major and minor salivary glands. Its primary pulmonary presentation is very rare, it can manifest with central airway obstruction and extensive lung involvement. Although it is slow growing, it has a tendency to local recurrence and late hematogenous metastases. Read More

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http://dx.doi.org/10.1016/j.rmcr.2018.11.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280630PMC
November 2018

A case series on the conservative management of the bony skull in patients with aggressive skin carcinomas of the scalp.

J Surg Case Rep 2018 Dec 11;2018(12):rjy326. Epub 2018 Dec 11.

Head and Neck Department, Guy's Hospital, London, UK.

Few studies examine techniques of surgical resection for scalp malignancies to ensure clear margins. We present a case series utilizing outer cortex removal in patients without evidence of bony or pericranial invasion. A retrospective casenote review is presented of three cases treated in a tertiary Head and Neck Cancer Centre. Read More

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http://dx.doi.org/10.1093/jscr/rjy326DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289215PMC
December 2018
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F-FDG PET/MRI vs MRI in patients with recurrent adenoid cystic carcinoma.

Head Neck 2019 Jan 13;41(1):170-176. Epub 2018 Dec 13.

Department of Nuclear Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

Objectives: To evaluate and compare the diagnostic potential of F-fluorodeoxyglucose positron emission tomography/magnetic resonance imaging ( FDG-PET/MRI) and MRI for recurrence diagnostics after primary therapy in patients with adenoid cystic carcinoma (ACC).

Methods: A total of 32 dedicated head and neck F-FDG PET/MRI datasets were included in this analysis. MRI and F-FDG PET/MRI datasets were analyzed in separate sessions by two readers for tumor recurrence or metastases. Read More

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http://dx.doi.org/10.1002/hed.25485DOI Listing
January 2019

A retrospective multicenter study of carbon-ion radiotherapy for external auditory canal and middle ear carcinomas.

Cancer Med 2019 Jan 8;8(1):51-57. Epub 2018 Dec 8.

Hospital of the National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Sciences and Technology, Chiba, Japan.

Background: We conducted a retrospective multicenter study to assess the clinical outcomes of carbon-ion radiotherapy (CIRT) for head and neck malignancies (Japan Carbon-Ion Radiation Oncology Study Group [J-CROS] study: 1402 HN). We aimed to evaluate the safety and efficacy of CIRT in patients with external auditory canal (EAC) and middle ear (ME) carcinomas.

Methods: Thirty-one patients treated with CIRT at four Japanese institutions were analyzed. Read More

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http://dx.doi.org/10.1002/cam4.1830DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346229PMC
January 2019