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    276 results match your criteria Cutaneous Cryptococcus

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    Biosynthesized silver and gold nanoparticles are potent antimycotics against opportunistic pathogenic yeasts and dermatophytes.
    Int J Nanomedicine 2018 1;13:695-703. Epub 2018 Feb 1.
    Department of Microbiology, Faculty of Science and Informatics, University of Szeged, Szeged.
    Background: Epidemiologic observations indicate that the number of systemic fungal infections has increased significantly during the past decades, however in human mycosis, mainly cutaneous infections predominate, generating major public health concerns and providing much of the impetus for current attempts to develop novel and efficient agents against cutaneous mycosis causing species. Innovative, environmentally benign and economic nanotechnology-based approaches have recently emerged utilizing principally biological sources to produce nano-sized structures with unique antimicrobial properties. In line with this, our aim was to generate silver nanoparticles (AgNPs) and gold nanoparticles (AuNPs) by biological synthesis and to study the effect of the obtained nanoparticles on cutaneous mycosis causing fungi and on human keratinocytes. Read More

    Disseminated cryptococcosis presenting initially as lower limb cellulitis in a renal transplant recipient - a case report.
    BMC Nephrol 2018 01 27;19(1):18. Epub 2018 Jan 27.
    Department of Medicine, Mackay Base Hospital, Bridge Road, Mackay, Australia.
    Background: Cellulitis is an unusual presentation of disseminated cryptococcosis, a serious infection seen predominantly in immunocompromised hosts. Disseminated cryptococcosis carries significant morbidity for transplant recipients, especially of the pulmonary and central nervous systems, and carries a high mortality risk.

    Case Presentation: We report a 59-year-old renal transplant recipient who presented with bilateral lower leg cellulitis without other symptoms or signs. Read More

    First case of superficial infection due(formerly) in Iran: A review of the literature.
    Curr Med Mycol 2017 Jun;3(2):33-37
    Department of Medical Mycology and Parasitology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
    Background And Purpose: (formerly) is a non-neoformans cryptococcal species rarely isolated as a human pathogen.

    Case Report: Herein, we present the case of a 26-year-old Iranian man with a superficial cutaneous lesion in the axilla. The initial treatment for pityriasis versicolor by clotrimazole was unsuccessful. Read More

    Eugenol Induces Phenotypic Alterations and Increases the Oxidative Burst in.
    Front Microbiol 2017 7;8:2419. Epub 2017 Dec 7.
    Departamento de Farmácia, Universidade Federal de Juiz de Fora - Campus Governador Valadares, Governador Valadares, Brazil.
    Eugenol is a phenolic compound and the main constituent of the essential oil of clove India. Although there are reports of some pharmacological effects of eugenol, this study is the first that proposes to evaluate the antifungal effects of this phenol against bothandcells. The effect of eugenol against yeast cells was analyzed for drug susceptibility, alterations in cell diameter, capsule properties, amounts of ergosterol, oxidative burst, and thermodynamics data. Read More

    Disseminated cryptococcosis with skin lesions: report of a case series.
    An Bras Dermatol 2017 ;92(5 Suppl 1):69-72
    Department of Pathology, Escola Paulista de Medicina - Universidade Federal de São Paulo (EPM-UNIFESP) - São Paulo (SP), Brazil.
    Cryptococcosis is a common fungal infection in immunocompromised patients, caused by genus Cryptococcus, presenting with meningitis, pneumonia, and skin lesions. Cutaneous presentation can be varied, but specifically in solid organ transplant recipients (iatrogenically immunocompromised), cryptococcosis should always be considered in the differential diagnosis of cellulitis-like lesions, since the delay in diagnosis leads to worse prognosis and fatal outcome. We report four cases of cryptococcosis with cutaneous manifestation not only for its rarity, but also to emphasize the important role of the dermatologist in the diagnosis of this disease. Read More

    Dermatological Complications After Solid Organ Transplantation.
    Clin Rev Allergy Immunol 2018 Feb;54(1):185-212
    Division of Gastroenterology and Center for Autoimmune Liver Diseases, Department of Medicine and Surgery, University of Milan-Bicocca, Milan, Italy.
    Organ transplant recipients (OTRs) are a population at high risk for cutaneous adverse events. Their early recognition and appropriate treatment is an important component of the clinical management of OTRs and should be optimally dealt with by dermatologists working in the context of a transplant dermatology clinic. Skin examination should be a standard procedure before performing organ transplantation to assess conditions which may be difficult to manage after the transplant procedure has been performed or which may represent a contraindication to transplantation, e. Read More

    Asymptomatic Meningitis and Lung Cavity in a Case of Cryptococcosis.
    Am J Case Rep 2017 Oct 26;18:1140-1144. Epub 2017 Oct 26.
    Department of Infectious Diseases, Capital Medical University Affiliated Beijing You An Hospital, Beijing Institute of Hepatology, Beijing, China (mainland).
    BACKGROUND Cryptococcus neoformans (C. neoformans) infection is one of the most common opportunistic infections in AIDS patients. C. Read More

    Cryptococcal cellulitis: A rare entity histologically mimicking a neutrophilic dermatosis.
    J Cutan Pathol 2018 Jan 20;45(1):90-93. Epub 2017 Nov 20.
    Department of Dermatology, St. Joseph Mercy Health System, Ypsilanti, Michigan.
    Cutaneous Cryptococcus infection presents classically with granulomatous and gelatinous reactive patterns. Cases mimicking neutrophilic dermatoses have not been described. Conversely, neutrophilic dermatoses with degrading cells mimicking cryptococcal organisms have been reported. Read More

    Scalp Lesions in a Pediatric Patient with Hyper IgM Syndrome: Clinical and Histologic Mimicry of Cryptococcus neoformans Infection.
    J Pediatr 2018 Jan 28;192:256-258. Epub 2017 Sep 28.
    Department of Pediatrics, Columbia University Medical Center, New York, NY; Department of Dermatology, Columbia University Medical Center, New York, NY.
    We report a case of cutaneous cryptococcosis due to Cryptococcus neoformans in a pediatric patient with hyper IgM syndrome with scalp lesions that resembled tinea capitis on gross examination and mimicked juvenile xanthogranuloma on histologic examination. This case highlights the importance of considering cutaneous cryptococcosis in patients with hyper IgM syndrome. Read More

    Cryptococcal Infection in Transplant Kidney Manifesting as Chronic Allograft Dysfunction.
    Indian J Nephrol 2017 Sep-Oct;27(5):392-394
    Department of Internal Medical, Armed Forces Medical College, Pune, Maharashtra, India.
    Invasive fungal infections (IFIs) are a significant cause of morbidity in solid organ transplant (SOT) recipients. Common causes among them are,, and. Antifungal prophylaxis has led to decrease in overall incidence of IFI; however, there is very little decline in the incidence of Cryptococcal infections of SOT recipients because effective prophylaxis is not available against this infectious agent. Read More

    First report of two cases of cryptococcosis in Tripoli, Libya, infected with Cryptococcus neoformans isolates present in the urban area.
    J Mycol Med 2017 Sep 31;27(3):421-424. Epub 2017 May 31.
    Lab. Micologia Medica, Dipartimento di Scienze Biomediche per la Salute, Università degli Studi di Milano, Via Pascal 36, 20133, Milano, Italy. Electronic address:
    Cryptococcosis is a potentially fatal fungal disease caused by the basidiomycetes yeasts Cryptococcus neoformans and C. gattii with high predilection to invade the central nervous system mainly in immunocompromised hosts. Skin can be secondarily involved in disseminated infection or be exceptionally involved as primary cutaneous infection by inoculation with contaminated materials. Read More

    Microbial Disease Spectrum Linked to a Novel IL-12Rβ1 N-Terminal Signal Peptide Stop-Gain Homozygous Mutation with Paradoxical Receptor Cell-Surface Expression.
    Front Microbiol 2017 13;8:616. Epub 2017 Apr 13.
    Núcleo de Diagnóstico e Investigação Molecular, Laboratório de Biotecnologia, Universidade Estadual do Norte FluminenseCampos dos Goytacazes, Brazil.
    Patients with Mendelian Susceptibility to Mycobacterial Diseases (MSMD) exhibit variable vulnerability to infections by mycobacteria and other intramacrophagic bacteria (e.g.,and) and fungi (e. Read More

    Progressive cutaneous Cryptococcosis complicated with meningitis in a myasthenia gravis patient on long-term immunosuppressive therapy - a case report.
    BMC Infect Dis 2017 04 26;17(1):311. Epub 2017 Apr 26.
    Department of Dermatology, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.
    Background: Cryptococcosis is an opportunistic infection caused by the encapsulated yeast Cryptococcus neoformans and most remarkably manifests in HIV-infected individuals, especially in the settings of very low CD4 count. Development of cryptococcosis in HIV-uninfected individuals is exceedingly rare and usually signifies a marked immunodeficiency. Cryptococcosis in association with myasthenia gravis or thymoma has been previously documented in only very few cases in the literature. Read More

    Disseminated cryptococcosis manifested as a single tumor in an immunocompetent patient, similar to the cutaneous primary forms.
    An Bras Dermatol 2016 Sep-Oct;91(5 suppl 1):29-31
    Universidade do Oeste Paulista (Unoeste) - Presidente Prudente (SP), Brazil.
    Cryptococcosis is a fungal infection caused by Cryptococcus neoformans that tends to affect immunocompromised individuals. The fungi are mostly acquired by inhalation, which leads to an initial pulmonary infection. Later, other organs - such as the central nervous system and the skin - can be affected by hematogenous spread. Read More

    Atypical cutaneous cryptococcosis in four cats in the USA.
    Vet Dermatol 2017 Aug 29;28(4):405-e97. Epub 2017 Jan 29.
    Dermatopathology Specialty Service, College of Veterinary Medicine & Biomedical Science, Texas A&M University, College Station, TX, 77843, USA.
    Background: Cryptococcosis is an uncommon fungal infection in humans and mammals. Occasionally, cryptococcosis manifests as cutaneous lesions, either as an extension of nasal disease or as stand alone lesions unassociated with the nose. Histologically, these lesions are typically characterized by abundant organisms with mild granulomatous dermatitis. Read More

    Cellulitis in a Liver Transplant Patient as an Initial Manifestation of Disseminated Cryptococcal Disease.
    Case Rep Dermatol 2016 Sep-Dec;8(3):250-253. Epub 2016 Oct 4.
    Departamento de Doenças Infecciosas, Hospital Federal dos Servidores do Estado do Rio de Janeiro (HFSE), Rio de Janeiro, Brazil.
    A 50-year-old male underwent liver transplantation due to cryptogenic cirrhosis and was admitted with severe pain in the left leg as well as phlogosis. Amoxicillin/clavulanic acid was prescribed, assuming bullous erysipelas. Among the tests performed, the latex agglutination test for thesp. Read More

    Pseudozyma and other non-Candida opportunistic yeast bloodstream infections in a large stem cell transplant center.
    Transpl Infect Dis 2017 Apr 6;19(2). Epub 2017 Mar 6.
    Division of Infectious Diseases, Rush University Medical Center, Chicago, IL, USA.
    Non-Candida opportunistic yeasts are emerging causes of bloodstream infection (BSI) in immunocompromised hosts. However, their clinical presentation, management, and outcomes in stem cell transplant (SCT) recipients are not well described. We report the first case to our knowledge of Pseudozyma BSI in a SCT recipient. Read More

    Disseminated cryptococcosis with cutaneous involvement in an immunocompetent patient.
    An Bras Dermatol 2016 Nov-Dec;91(6):832-834
    Universidade Federal de Mato Grosso do Sul (UFMS) - Campo Grande (MS), Brasil.
    Cryptococcosis is a fungal infection of opportunistic behavior that is unusual in immunocompetent patients. We report a rare case of disseminated cryptococcosis with cutaneous involvement in an immunocompetent individual. During hospitalization, Cryptococcus gattii was isolated from skin lesions, lung and spinal fluid. Read More

    Intestinal Lesion in a Dog Due to Cryptococcus gattii Type VGII and Review of Published Cases of Canine Gastrointestinal Cryptococcosis.
    Mycopathologia 2017 Jun 17;182(5-6):597-602. Epub 2016 Dec 17.
    Universidade Federal Rural do Rio de Janeiro (UFRRJ), Seropédica, RJ, Brazil.
    Cryptococcosis is a mycosis caused by yeasts of genus Cryptococcus, mainly the species C. neoformans and C. gattii that can affect humans and animals. Read More

    Experience with Splenic Abscess from Southern India.
    J Clin Diagn Res 2016 Oct 1;10(10):OC22-OC25. Epub 2016 Oct 1.
    Professor & Head, Department of General Medicine, Nizam's Institute of Medical Sciences , Hyderabad, Telangana, India .
    Introduction: Splenic abscess is a rare entity with potentially life threatening complications. Sparse recent published data are available documenting the aetiological profile and management of patients with splenic abscess from India.

    Aim: To study the clinical profile of splenic abscess. Read More

    Disseminated Cryptococcosis in a 63-year-old Patient with Multiple Sclerosis Treated with Fingolimod.
    Intern Med 2016;55(22):3383-3386. Epub 2016 Nov 15.
    Department of General Internal Medicine, Kobe University Hospital, Japan.
    We herein report the case of a 63-year-old man who presented with a 3-month history of a cutaneous nodular lesion of his jaw, low grade fever, lethargy and progressive cognitive impairment. He had a 30-year history of multiple sclerosis and had been treated with fingolimod for the previous 2 years. Laboratory data revealed CD4 lymphocytopenia and a tissue culture of the skin nodule was positive for Cryptococcus neoformans. Read More

    Disseminated cryptococcosis in an immunocompetent child.
    BMJ Case Rep 2016 Nov 16;2016. Epub 2016 Nov 16.
    Department of Pathology, Jawaharlal Nehru Medical College, Aligarh, Uttar Pradesh, India.
    Cryptococcus is a ubiquitous fungus and is known for causing meningitis and cutaneous infections in immunocompromised individuals. Disseminated cryptococcal infection is very rare and almost always found to occur in immunocompromised individuals especially in persons infected with HIV. This is particularly attributed to its capsulated spores. Read More

    Cryptococcosis in Renal Transplant Recipients: A Single-Center Experience.
    Transplant Proc 2016 Sep;48(7):2289-2293
    Department of Nephrology, Centro Hospitalar de São João, Alameda Prof. Hernâni Monteiro, Porto, Portugal.
    Background: In solid organ transplant patients, 8% of invasive fungal infections are attributed to Cryptococcus. The aim of this study was to determine the frequency, risk factors, clinical characteristics, and outcome of kidney transplant recipients (TR) infected with Cryptococcus.

    Case Series: Between 2007 and 2014, a total of 500 kidney transplantations were performed at São João Hospital, in Porto, Portugal. Read More

    Cryptococcal cellulitis on the shin of an immunosuppressed patient.
    Dermatol Online J 2016 Jun 15;22(6). Epub 2016 Jun 15.
    Departments of Dermatology University of Southern California Keck School of Medicine, Los Angeles, California.
    Cryptococcus neoformans is a common fungus found throughout the environment that causes opportunistic disease in immunocompromised individuals. Infection of humans with C neoformans usually manifests as lung disease through inhalation of spores or meningoencephalitis by involvement of the central nervous system. Rarely, dissemination in the form of cutaneous lesions can occur in individuals with long term immunosuppression. Read More

    Localized Cutaneous Cryptococcosis: Summary of Reported Cases in Japan.
    Med Mycol J 2016 ;57(3):E35-9
    Noguchi Dermatology Clinic.
    A 68-year-old male plasterer with no history of trauma presented to our clinic in March 2012 with a 16×14-mm ulcer that developed following a crushed small papule on the right anterior chest. In April 2012, the patient was referred to another hospital, where cutaneous cryptococcosis was diagnosed based on discharge culture results. The patient was treated with oral itraconazole at a dose of 150 mg/day for 10 weeks; however, the ulcer remained unchanged and he discontinued the treatment. Read More

    Multilocus sequence typing analysis reveals that Cryptococcus neoformans var. neoformans is a recombinant population.
    Fungal Genet Biol 2016 Feb 6;87:22-9. Epub 2016 Jan 6.
    Molecular Microbiology Section, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA.
    Cryptococcus neoformans var. neoformans (serotype D) represents about 30% of the clinical isolates in Europe and is present less frequently in the other continents. It is the prevalent etiological agent in primary cutaneous cryptococcosis as well as in cryptococcal skin lesions of disseminated cryptococcosis. Read More

    Cryptococcal panniculitis in a renal transplant recipient: case report and review of literature.
    J Dermatol Case Rep 2015 Sep 30;9(3):76-80. Epub 2015 Sep 30.
    Department of Pathology, SMS Medical College and Attached Hospitals, Jaipur, Rajasthan India.
    Background: Cryptococcosis is a deep fungal infection caused by Cryptococcus neoformans. The infection usually involves the lungs, the central nervous system as well as the skin, the bones and the urinary tract. Immunocompromised individuals, including solid organ transplant recipients, are at higher risk for cryptococcal infections. Read More

    Disseminated cryptococcosis in an apparently immunocompetent patient presenting with primary intraventricular haemorrhage.
    BMJ Case Rep 2015 Oct 22;2015. Epub 2015 Oct 22.
    Department of General Medicine, Calcutta National Medical College and Hospital, Kolkata, West Bengal, India.
    Disseminated cryptococcosis is uncommon and almost always occurs in HIV-infected patients. However, cryptococcosis can also be found in patients of organ transplantation, in those on disease modifying agents for rheumatological conditions and in patients with underlying immunodeficiency. Cryptococcal infection may occur in an immunocompetent patient, but the pathogenic strain is usually Cryptococcus gattii, and not C. Read More

    Fatal primary cutaneous cryptococcosis: case report and review of published literature.
    Ir J Med Sci 2016 Nov 6;185(4):959-963. Epub 2015 Aug 6.
    National Clinical Research Center of Kidney Disease, Jinling Hospital, Nanjing University Clinical School of Medicine, 305 East Zhongshan Road, Nanjing, Jiangsu Province, 210002, China.
    Objective: Cryptococcus is an opportunistic yeast with a worldwide distribution that primarily causes significant infections in immunocompromised individuals, generally by affecting the respiratory tract. But primary cutaneous cryptococcosis (PCC) without systemic infection is rare. We report a case of PCC in a patient with nephrotic syndrome. Read More

    Primary capsule-deficient cutaneous cryptococcosis in a sporotrichoid pattern in an immunocompetent host.
    Cutis 2015 Jul;96(1):E26-9
    11007 Blan Avon Rd, Midlothian, MD 21543, USA.
    Cryptococcosis is an opportunistic yeast infection caused by Cryptococcus neoformans that remains the most common systemic fungal infection in immunosuppressed patients and often presents with signs of meningitis. Primary cutaneous cryptococcosis (PCC) is a more rare clinical identity that is characterized by skin lesions confined to 1 body region, often presenting as a whitlow or phlegmon with positive culture for C neoformans and no evidence of simultaneous dissemination. We report a rare case of PCC in a 73-year-old man with intact cell-mediated immunity. Read More

    Cutaneous Cryptococcus: marker for disseminated infection.
    BMJ Case Rep 2015 Jul 21;2015. Epub 2015 Jul 21.
    Department of Dermatology and Venereology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
    Cryptococcosis is an infection caused by the encapsulated yeast, Cryptococcus neoformans, a dimorphic fungus recovered from pigeon excreta, soil, dust and human skin. After a primary infection in the lungs, the disease can disseminate via a haematogenous route to various organs, including the central nervous system and skin, in susceptible individuals. Cryptococcosis can present with a variety of skin and soft tissue manifestations including acneiform lesions, purpura, vesicles, nodules, abscesses, ulcers, granulomas, pustules, draining sinuses and cellulitis. Read More

    Cryptococcal meningitis presenting with headache and a pustular eruption in a heart transplant patient.
    Transpl Infect Dis 2015 Oct 14;17(5):716-8. Epub 2015 Aug 14.
    Departments of Dermatology and Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
    Cryptococcosis is a fungal infection that typically occurs in severely immunocompromised patients. Here, we report the case of a heart transplant recipient who presented with cutaneous lesions and was diagnosed with disseminated cryptococcosis and then cryptococcal meningitis on the basis of positive Tzanck smear of the lesions, confirmed by culture, highlighting the importance of the skin as a window to systemic disease. Read More

    Blepharitis due toin a cat from northern Portugal.
    JFMS Open Rep 2015 Jul-Dec;1(2):2055116915593963. Epub 2015 Jul 6.
    Department of Veterinary Sciences, School of Agrarian and Veterinary Sciences, University of Trás-os-Montes e Alto Douro, Vila Real, Portugal.
    We report a clinical case of blepharitis due toyeasts in a 2-year-old stray cat from northern Portugal (Vila Real) without concurrent naso-ocular signs. Ophthalmological examination revealed mucopurulent discharge from an open wound in the right upper and lower lids. Slit-lamp biomicroscopy showed a normal anterior segment, and intraocular pressure was within the normal reference interval. Read More

    Pancytopenia and cutaneous cryptococcosis as an indicator disease of acquired immune deficiency syndrome.
    Indian J Med Microbiol 2015 Jul-Sep;33(3):439-42
    Department of Microbiology, Regional Institute of Medical Sciences, Imphal, Manipur, India.
    We present a case of pancytopenia and cutaneous cryptococcosis in a young girl with no complaints of fever, headache and vomiting. Fine-needle aspiration cytology and further investigation for pancytopenia revealed presence of Cryptococcus in skin and bone marrow aspirates. Fungal cultures of the skin aspirates, blood and bone marrow confirmed cryptococcal infection. Read More

    [Cutaneous cryptococcosis mimicking basal cell carcinoma and revealing systemic involvement in acquired immunodeficiency].
    J Mycol Med 2015 Jun 8;25(2):163-8. Epub 2015 May 8.
    Service de dermatologie, faculté de médecine et de pharmacie, université Cadi Ayyad, hôpital Errazi, CHU Mohamed VI, 40000 Marrakech, Maroc.
    Background: Cryptococcosis is a rare and a serious opportunistic infection that occurs primarily on the field of immunodeficiency. We report a case of disseminated cryptococcosis in acquired immunodeficiency syndrome revealed by unusual skin lesions.

    Observation: A 52-year-old patient consulted for two crusty ulcerative lesions situated on the left supraorbital and on the nasal tip that appeared 6 months ago. Read More

    [Tropical and travel-related dermatomycoses : Part 2: cutaneous infections due to yeasts, moulds, and dimorphic fungi].
    Hautarzt 2015 Jul;66(7):522-32
    Labor für medizinische Mikrobiologie, Partnerschaft Prof. Dr. med. Pietro Nenoff & Dr. med. Constanze Krüger, Straße des Friedens 8, 04579, Mölbis, Deutschland,
    Besides dermatophytoses, a broad range of cutaneous infections due to yeasts and moulds may occur in subtropical and tropical countries where they can affect travellers. Not to be forgotten are endemic occurring dimorphic or biphasic fungi in countries with hot climate, which cause systemic and secondary cutaneous infections in immunosuppressed and immunocompetent people. In the tropics, the prevalence of pityriasis versicolor, caused by the lipophilic yeast Malassezia spp. Read More

    Isolated cutaneous cryptococcosis in clinically unsuspected idiopathic CD4 lymphocytopenia.
    J Cytol 2014 Oct-Dec;31(4):230-2
    Department of Pathology, Maulana Azad Medical College and Associated LNJP Hospital, New Delhi, India.
    Idiopathic CD4 lymphocytopenia first defined in 1992 by the U.S. Centers for Disease Control and Prevention, as the repeated presence of a CD4(+) T-lymphocyte count of fewer than 300 cells/cumm or of <20% of total T-cells with no evidence of human immunodeficiency virus (HIV) infection and therapy that might cause depressed CD4 T-cells. Read More

    Systemic Review of Published Reports on Primary Cutaneous Cryptococcosis in Immunocompetent Patients.
    Mycopathologia 2015 Aug 4;180(1-2):19-25. Epub 2015 Mar 4.
    Department of Dermatology and Mycology Center, Changzheng Hospital, Second Military Medical University, Shanghai, 200003, China.
    Primary cutaneous cryptococcosis (PCC) has been confirmed as a distinct clinical entity with secondary cutaneous cryptococcosis from systematic infection since 2003. Although it has been confirmed as a distinct clinical entity, little has progressed on PCC in immunocompetent hosts compared to their immunocompromised counterpart. We reviewed the literature on cases of PCC in immunocompetent patients from 2004 to 2014, and 21 cases from 16 reports were identified. Read More

    Primary cutaneous cryptococcosis treated with debridement and fluconazole monotherapy in an immunosuppressed patient: a case report and review of the literature.
    Case Rep Infect Dis 2015 2;2015:131356. Epub 2015 Feb 2.
    Division of Infectious Diseases, Department of Internal Medicine, University of Virginia, Charlottesville, VA 22903, USA.
    Cryptococcus neoformans is an opportunistic yeast present in the environment. Practitioners are familiar with the presentation and management of the most common manifestation of cryptococcal infection, meningoencephalitis, in patients with AIDS or other conditions of immunocompromise. There is less awareness, however, of uncommon presentations where experience rather than evidence guides therapy. Read More

    Primary cutaneous cryptococcosis in an eight-year-old immunocompetent child: how to treat?
    Klin Padiatr 2015 Jan 7;227(1):41-4. Epub 2015 Jan 7.
    University Medical Center Freiburg, Department of Pediatrics and Adolescent Medicine, Freiburg, Germany.
    Here we report on a case of primary cryptococcal skin infection in an immunocompetent 8-year-old boy. The infection first manifested itself as a subcutaneous abscess around the proximal joint of his right thumb after a minor injury from contact with a thorny shrub. After surgical incision and drainage was performed, Cryptococcus neoformans var. Read More

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