630 results match your criteria Current problems in cardiology[Journal]


New Insights Into the Comorbidity of Coronary Heart Disease and Depression.

Curr Probl Cardiol 2019 Mar 12. Epub 2019 Mar 12.

Coronary heart disease (CHD) and depression are common disorders that markedly impair quality of life and impose a great financial burden on society. They are also frequently comorbid, exacerbating patient condition, and worsening prognosis. This comorbidity strongly suggests shared pathologic mechanisms. Read More

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http://dx.doi.org/10.1016/j.cpcardiol.2019.03.002DOI Listing
March 2019
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Correlation Between Aortic Angulation and Outcomes of Transcatheter Aortic Valve Replacement With New-Generation Valves.

Curr Probl Cardiol 2019 Mar 14. Epub 2019 Mar 14.

The aim of this study was to assess the correlation of aortic angulation (AA) on immediate postprocedural and long-term outcomes following transcatheter aortic valve replacement (TAVR) with new-generation valves. There is limited and conflicting data on the impact of AA on short- and long-term outcomes in patients undergoing TAVR. Available studies to date were done with first-generation valves. Read More

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http://dx.doi.org/10.1016/j.cpcardiol.2019.03.004DOI Listing
March 2019
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Current Evidence and Rationale of Percutaneous Therapy for Chronic Total Coronary Occlusions.

Curr Probl Cardiol 2019 Mar 12. Epub 2019 Mar 12.

The prevalence of chronic total occlusion (CTO) lesions in coronary arteries is notably high in patients with significant coronary artery disease. However, only a relatively small fraction of observed CTOs classically go for revascularization. Recent advances in techniques and equipment has greatly improved the success rates of CTO revascularization while reducing complications. Read More

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http://dx.doi.org/10.1016/j.cpcardiol.2019.03.001DOI Listing
March 2019
5 Reads

Does Insurance Effect the Outcome in Patients With Acute Coronary Syndrome?: An Insight from the Most Recent National Inpatient Sample.

Curr Probl Cardiol 2019 Feb 28. Epub 2019 Feb 28.

Several studies have shown disparities in outcome in the patients with Acute coronary syndrome (ACS) based on several factors. Treatment might differ based on insurance type. Therefore, we retrospectively analyzed National Inpatient Sample (NIS 2016) data to identify the impact of different types of insurances on mortality outcome in patients admitted with ACS. Read More

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http://dx.doi.org/10.1016/j.cpcardiol.2019.02.003DOI Listing
February 2019
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Curr Probl Cardiol 2019 Jun;44(6):180

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http://dx.doi.org/10.1016/j.cpcardiol.2019.03.005DOI Listing

Update and Unmet Needs on the Use of Nonvitamin K Oral Anticoagulants for Stroke Prevention in Patients With Atrial Fibrillation.

Curr Probl Cardiol 2019 Feb 27. Epub 2019 Feb 27.

The landscape of stroke prevention in patients with atrial fibrillation (AF) is rapidly changing after the introduction of nonvitamin K oral anticoagulants (NOACs) that are replacing in many countries the use of vitamin K antagonists in virtue of their similar efficacy and better safety. The European Heart Rhythm Association has proposed a new classification for AF patients with valvular heart disease (VHD), which has clinical implications for the most appropriate choice of antithrombotic strategy. Furthermore, a growing body of evidence is available on the use of NOACs in patients with VHD. Read More

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http://dx.doi.org/10.1016/j.cpcardiol.2019.02.002DOI Listing
February 2019
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Curr Probl Cardiol 2019 May;44(5):144

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Drug-eluting Stents Versus Bare-metal Stents for Saphenous Vein Graft Interventions: A Systematic Review and Meta-analysis of Studies With Longer Follow-up.

Curr Probl Cardiol 2019 Jan 8. Epub 2019 Jan 8.

Randomized controlled trials comparing drug eluting stents (DES) with bare-metal stents (BMS) for saphenous vein graft (SVG) interventions have shown conflicting results. We conducted this meta-analysis to evaluate the cumulative evidence for long-term efficacy and safety of DES vs BMS in SVG lesions. A systematic search was conducted of Randomized controlled trials comparing DES vs BMS in patients undergoing percutaneous interventions for SVG lesions. Read More

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http://dx.doi.org/10.1016/j.cpcardiol.2018.12.002DOI Listing
January 2019
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Curr Probl Cardiol 2018 Dec;43(12):444

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http://dx.doi.org/10.1016/j.cpcardiol.2018.10.001DOI Listing
December 2018

Aging, MicroRNAs, and Heart Failure.

Curr Probl Cardiol 2018 Dec 29. Epub 2018 Dec 29.

Aging is a major risk factor for heart failure, one of the leading causes of death in Western society. The mechanisms that underlie the different forms of heart failure have been elucidated only in part and the role of noncoding RNAs is still poorly characterized. Specifically, microRNAs (miRNAs), a class of small noncoding RNAs that can modulate gene expression at the posttranscriptional level in all cells, including myocardial and vascular cells, have been shown to play a role in heart failure with reduced ejection fraction. Read More

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http://dx.doi.org/10.1016/j.cpcardiol.2018.12.003DOI Listing
December 2018
2 Reads

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Curr Probl Cardiol 2019 Apr;44(4):114

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Modern Management of ST-Segment Elevation Myocardial Infarction.

Curr Probl Cardiol 2018 Sep 14. Epub 2018 Sep 14.

Disruption of intracoronary plaque with thrombus formation resulting in severe or total occlusion of the culprit coronary artery provides the pathophysiologic foundation for ST-segment elevation myocardial infarction (STEMI). Management of STEMI focuses on timely restoration of coronary blood flow along with antithrombotic therapies and secondary prevention strategies. The purpose of this review is to discuss the epidemiology, pathophysiology, and diagnosis of STEMI. Read More

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http://dx.doi.org/10.1016/j.cpcardiol.2018.08.005DOI Listing
September 2018
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Curr Probl Cardiol 2019 Mar;44(3):90

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March 2019
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Curr Probl Cardiol 2019 Feb;44(2):44

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http://dx.doi.org/10.1016/j.cpcardiol.2018.11.003DOI Listing
February 2019
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The Medical and Endovascular Treatment of PAD: A Review of the Guidelines and Pivotal Clinical Trials.

Curr Probl Cardiol 2018 Nov 30. Epub 2018 Nov 30.

Peripheral arterial disease (PAD) is a global health problem. The risk factors for developing PAD have been clearly described in the literature, as have the medical therapies and preventative strategies for the prevention and treatment of PAD. Unfortunately, PAD patients remain undertreated with regard to guideline-directed medical therapy. Read More

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http://dx.doi.org/10.1016/j.cpcardiol.2018.09.004DOI Listing
November 2018
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Increasing Diversity in Clinical Trials: Overcoming Critical Barriers.

Curr Probl Cardiol 2019 May 9;44(5):148-172. Epub 2018 Nov 9.

Clinical trial results provide the critical evidence base for evaluating the safety and efficacy of new medicines and medical products. Efficacy and safety may differ among population subgroups depending on intrinsic/extrinsic factors, including sex, age, race, ethnicity, lifestyle, and genetic background. Racial and ethnic minorities continue to be underrepresented in cardiovascular and other clinical trials. Read More

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May 2019
3 Reads

Significance of Pulmonary Hypertension in Hypertrophic Cardiomyopathy.

Curr Probl Cardiol 2018 Oct 17. Epub 2018 Oct 17.

Hypertrophic cardiomyopathy (HCM) is the most prevalent hereditary cardiac disease characterized by the presence of left ventricular and/or septal hypertrophy in the absence of other underlying cardiac disorders. Patients of HCM have a broad range of clinical presentation from being asymptomatic to severely ill condition requires hospitalization and urgent management. Broadly, HCM is classified in two variants: obstructive and nonobstructive. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01462806183015
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http://dx.doi.org/10.1016/j.cpcardiol.2018.10.002DOI Listing
October 2018
15 Reads
3.000 Impact Factor

The Role of Microbiota in Cardiovascular Risk: Focus on Trimethylamine Oxide.

Curr Probl Cardiol 2019 Jun 7;44(6):182-196. Epub 2018 Jul 7.

The extensive collection of bacteria cohabiting within the host collaborates with human functions and metabolisms in both health and disease. The fine equilibrium of commensals is tightly controlled and an imbalance ("dysbiosis") in the gut microbiota can play different roles in human disease. The development of new genome sequencing techniques has allowed a better understanding of the role of human gut microbiota. Read More

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http://dx.doi.org/10.1016/j.cpcardiol.2018.06.005DOI Listing
June 2019
12 Reads

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Curr Probl Cardiol 2019 Jan;44(1)

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January 2019
2 Reads

Misunderstood or Mistrusted? The Under-Utilization of the Wearable Cardioverter Defibrillator in Clinical Practice.

Curr Probl Cardiol 2018 Sep 18. Epub 2018 Sep 18.

Annually in the United States, sudden cardiac death (including out-of-hospital cardiac arrests) is responsible for over 300,000 deaths, comprising 40%-50% of total mortality rates from cardiovascular disease. Among the highest-risk patients are those with ischemic and nonischemic cardiomyopathy who have a reduced left ventricular ejection fraction (≤ 35%-40%). However, not everyone is a candidate for an implantable cardioverter defibrillator. Read More

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September 2018
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Gender Identity, Hormone Therapy, and Cardiovascular Disease Risk.

Curr Probl Cardiol 2018 Sep 20. Epub 2018 Sep 20.

Transgender individuals represent a medically underserved and under researched population. There is a growing number of studies illustrating the importance of hormone therapy treatments in transgender men and women to assist ameliorating gender dysphoria and promoting well-being. However, the cardiovascular effects of these hormones are controversial. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01462806183014
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http://dx.doi.org/10.1016/j.cpcardiol.2018.09.003DOI Listing
September 2018
22 Reads

Impact of Nutrition on CardiovascularFunction.

Curr Probl Cardiol 2018 Sep 11. Epub 2018 Sep 11.

The metabolic sources of energy for myocardial contractility include mainly free fatty acids (FFA) for 95%, and in lesser amounts for 5% from glucose and minimal contributions from other substrates such lactate, ketones, and amino acids. However, myocardial efficiency is influenced by metabolic condition, overload, and ischemia. During cardiac stress, cardiomyocytes increase glucose oxidation and reduce FFA oxidation. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01462806183011
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http://dx.doi.org/10.1016/j.cpcardiol.2018.08.003DOI Listing
September 2018
3 Reads

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Curr Probl Cardiol 2018 Nov;43(11):420

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November 2018
2 Reads

Outcomes of Percutaneous Antegrade Intraluminal Coronary Intervention of Chronic Total Occlusion With Remote Surgical Backup.

Curr Probl Cardiol 2018 Aug 22. Epub 2018 Aug 22.

Percutaneous coronary intervention (PCI) of chronic total occlusion (CTO) is not favored in facilities without on-site surgical backup. We reviewed outcomes of patients who had CTO intervention with remote surgical backup in our institution. All patients who underwent attempted antegrade intraluminal CTO PCI from January 2013 to July 2017 were analyzed. Read More

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http://dx.doi.org/10.1016/j.cpcardiol.2018.08.002DOI Listing
August 2018
4 Reads

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Curr Probl Cardiol 2018 Oct;43(10):396

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http://dx.doi.org/10.1016/j.cpcardiol.2018.08.001DOI Listing
October 2018
1 Read

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Curr Probl Cardiol 2018 Sep;43(9):362

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http://dx.doi.org/10.1016/j.cpcardiol.2018.07.002DOI Listing
September 2018
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SGLT-2 Inhibitors and Peripheral Artery Disease: A Statistical Hoax or Reality?

Curr Probl Cardiol 2018 Jul 6. Epub 2018 Jul 6.

Inhibitors of sodium-glucose cotransporters type-2 are the most recent addition to the armamentarium of oral antidiabetic agents. This class of drugs has shown promising results in glycemic control and most importantly to reduce cardiovascular disease (CVD) mortality risk. Despite the encouraging data, there is concern regarding their potential for causing or worsening peripheral artery disease (PAD), which may increase the risk of lower extremity amputations. Read More

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http://dx.doi.org/10.1016/j.cpcardiol.2018.06.004DOI Listing
July 2018
3 Reads
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Atrial Fibrillation and Deterioration in Cognitive Function.

Curr Probl Cardiol 2018 Jul 11. Epub 2018 Jul 11.

The link between atrial fibrillation and cognitive decline and dementia has gained interest of the medical community lately. More research is being conducted to prevent and or delay this morbidity as no curative therapy is available for cognitive decline and dementia. The exact mechanism of causation is unclear. Read More

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http://dx.doi.org/10.1016/j.cpcardiol.2018.07.001DOI Listing
July 2018
3 Reads

Empowering the Aging with Mobile Health: A mHealth Framework for Supporting Sustainable Healthy Lifestyle Behavior.

Curr Probl Cardiol 2018 Jul 9. Epub 2018 Jul 9.

Healthcare providers are shifting to a value-based model that acknowledges the importance of a healthy lifestyle for managing chronic disease and mental health. This approach empowers patients to adopt and/or sustain healthy lifestyle choices through the use of innovative technologies-providing beneficial ways of delivering health literacy, self-monitoring, and patient-provider collaboration. Such pathways have the potential to enable healthy lifestyle management for a growing U. Read More

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http://dx.doi.org/10.1016/j.cpcardiol.2018.06.003DOI Listing
July 2018
3 Reads

Risk Reduction to Disease Management: Clinical Pharmacists as Cardiovascular Care Providers.

Curr Probl Cardiol 2018 Aug 4. Epub 2018 Aug 4.

Most cardiovascular diseases are caused by modifiable risk factors yet prevalence continues to increase and heart disease remains the leading cause of death in the United States. Screening, identifying and appropriately managing high risk patients are strategies to shift the paradigm from treatment to prevention. Pharmacists are an underutilized population health resource despite robust evidence to support their roles as interdisciplinary team members and direct patient care providers in both inpatient and outpatient settings. Read More

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http://dx.doi.org/10.1016/j.cpcardiol.2018.07.003DOI Listing
August 2018
2 Reads

Ultrasonography in Heart Failure: A Story that Matters.

Curr Probl Cardiol 2019 Apr 21;44(4):116-136. Epub 2018 Jun 21.

Heart failure (HF) is a clinical syndrome caused by structural and/or functional cardiac abnormalities, resulting in a reduced cardiac output and/or elevated intracardiac pressures at rest or during stress. It is the leading cause of hospitalization in Internal Medicine departments. This article aims at reviewing evidence of the importance of ultrasound in HF both for hospitalized patients and in the follow-up. Read More

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http://dx.doi.org/10.1016/j.cpcardiol.2018.05.003DOI Listing
April 2019
16 Reads

Applying Precision Medicine to Healthy Living for the Prevention and Treatment of Cardiovascular Disease.

Curr Probl Cardiol 2018 Dec 14;43(12):448-483. Epub 2018 Jun 14.

Healthy living medicine (HLM) is an emerging concept that recognizes the importance of: (1) Moving more and sitting less; (2) Consuming a healthy diet at the appropriate caloric load; (3) Maintaining a healthy body weight; and (4) Not smoking. Suffice to say, HLM should be practiced by all health professionals, prescribing a personalized healthy living polypill to individuals under their care while titrating the dosage for optimal adherence and therapeutic efficacy. Traditionally, HLM, particularly when practiced in the context of physical activity and diet, is commonly viewed as an all-or-none and one-size-fits-all paradigm. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01462806183008
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http://dx.doi.org/10.1016/j.cpcardiol.2018.06.001DOI Listing
December 2018
10 Reads

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Curr Probl Cardiol 2018 Aug;43(8):312

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http://dx.doi.org/10.1016/j.cpcardiol.2018.06.002DOI Listing
August 2018
2 Reads

Long QT Syndrome: A Comprehensive Review of the Literature and Current Evidence.

Curr Probl Cardiol 2019 Mar 10;44(3):92-106. Epub 2018 May 10.

Long QT syndrome (LQT) represents a heterogeneous family of cardiac electrophysiologic disorders characterized by QT prolongation and T-wave abnormalities on the electrocardiogram. It is commonly associated with syncope, however, sudden cardiac death can occur due to torsades de pointes. LQT is a clinical diagnosis and should be suspected in individuals on the basis of clinical presentation, family history and ECG characteristics. Read More

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http://dx.doi.org/10.1016/j.cpcardiol.2018.04.002DOI Listing
March 2019
7 Reads

Current Evidence-Based Understanding of the Epidemiology, Prevention, and Treatment of Atrial Fibrillation.

Curr Probl Cardiol 2018 Jun 7;43(6):241-283. Epub 2017 Jun 7.

Atrial fibrillation (AF) is the most common atrial arrhythmia in adults worldwide. As medical advancements continue to contribute to an ever-increasing aging population, the burden of atrial fibrillation on the modern health care system continues to increase. Therapies are also evolving, for treatment of the arrhythmia itself, and stroke risk mitigation. Read More

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http://dx.doi.org/10.1016/j.cpcardiol.2017.06.001DOI Listing
June 2018
3 Reads

Degenerative Mitral Stenosis: From Pathophysiology to Challenging Interventional Treatment.

Curr Probl Cardiol 2019 Jan 6;44(1):10-35. Epub 2018 Apr 6.

Mitral stenosis (MS) is characterized by obstruction of left ventricular inflow as a result of narrowing of the mitral valve orifice. Although its prevalence has declined over the last decade, especially in developed countries, it remains an important cause of morbidity and mortality.  The most often cause of MS worldwide is still postrheumatic mitral valve disease. Read More

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http://dx.doi.org/10.1016/j.cpcardiol.2018.03.004DOI Listing
January 2019
4 Reads

Enhancing Participation in Cardiac Rehabilitation: A Question of Proximity and Integration of Outpatient Services.

Curr Probl Cardiol 2018 Nov 6;43(11):424-435. Epub 2018 Mar 6.

Numerous investigations have established the strong clinical utility of cardiac rehabilitation, while clinical guidelines continually call for a high level of referral and participation. Historically, medical facilities have faced challenges referring eligible patients to cardiac rehabilitation, enrolling only a small portion of those receiving referral. Consequently, less than ~10% of qualifying patients receive any amount of cardiac rehabilitation. Read More

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http://dx.doi.org/10.1016/j.cpcardiol.2018.02.002DOI Listing
November 2018
12 Reads

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Curr Probl Cardiol 2018 May;43(5):188

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http://dx.doi.org/10.1016/j.cpcardiol.2018.03.001DOI Listing
May 2018
4 Reads

Let Us Talk About Moving: Reframing the Exercise and Physical Activity Discussion.

Curr Probl Cardiol 2018 Apr 7;43(4):154-179. Epub 2017 Jun 7.

Noncommunicable and chronic disease are interchangeable terms. According to the World Health Organization, "they are of long duration and generally slow progression. The 4 main types of chronic diseases are cardiovascular diseases (ie, heart attacks and stroke), cancers, chronic respiratory diseases (such as chronic obstructive pulmonary disease and asthma), and diabetes. Read More

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http://dx.doi.org/10.1016/j.cpcardiol.2017.06.002DOI Listing
April 2018
9 Reads

Assessing the Value of Moving More-The Integral Role of Qualified Health Professionals.

Curr Probl Cardiol 2018 Apr 11;43(4):138-153. Epub 2017 Jul 11.

School of Health Sciences, Faculty of Health, University of Tasmania, Launceston, TAS, Australia.

Being physically active or, in a broader sense, simply moving more throughout each day is one of the most important components of an individual's health plan. In conjunction with regular exercise training, taking more steps in a day and sitting less are also important components of one's movement portfolio. Given this priority, health care professionals must develop enhanced skills for prescribing and guiding individualized movement programs for all their patients. Read More

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http://dx.doi.org/10.1016/j.cpcardiol.2017.07.001DOI Listing
April 2018
8 Reads

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Curr Probl Cardiol 2018 Apr;43(4):134

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April 2018
4 Reads

Pathophysiology and Prevention of Heart Disease in Diabetes Mellitus.

Curr Probl Cardiol 2018 Mar 10;43(3):68-110. Epub 2017 May 10.

Diabetes mellitus (DM) has become a public health problem worldwide, and it has large implications for cardiovascular disease (CVD). In this article, we discuss the etiology and pathophysiology of CVD in DM including the effects of abnormal glucose homeostasis, genetic factors, epigenetics, apoptosis, common pathophysiological mechanisms shared by both DM and CVD, and contributions of other comorbidities. We then cover the pathogenesis of both atherosclerotic disease and cardiomyopathy in relation to DM. Read More

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March 2018
6 Reads

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Curr Probl Cardiol 2018 Mar 3;43(3):65. Epub 2018 Jan 3.

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http://dx.doi.org/10.1016/j.cpcardiol.2018.01.001DOI Listing
March 2018
4 Reads

Accurate Prediction of False ST-Segment Elevation Myocardial Infarction: Ready for Prime Time?

Curr Probl Cardiol 2018 Oct 3;43(10):400-412. Epub 2018 Jan 3.

The incidence of inappropriate cardiac catheterization lab activation for treatment of a false ST-segment elevation myocardial infarction (STEMI) has been reported to be 2.6%-36%. Excessive inappropriate catheterization lab activation may be associated with risks to patients, provider fatigue and improper resource usage. Read More

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http://dx.doi.org/10.1016/j.cpcardiol.2017.12.003DOI Listing
October 2018
6 Reads

Neurohormonal Imbalance: A Neglected Problem-And Potential Therapeutic Target-In Acute Heart Failure.

Curr Probl Cardiol 2018 Jul 16;43(7):294-304. Epub 2017 Dec 16.

Decompensated or acute heart failure (AHF) is characterized by increased ventricular and atrial pressures which may lead to and be caused by circulatory congestion. Unless due to a primary decrease in cardiac function, congestion arises from volume expansion or vasoconstriction. In turn, volume expansion and vasoconstriction are due to neurohormonal imbalance since both result from activation of the sympathetic nervous system, the renin-angiotensin-aldosterone axis and excess secretion of arginine vasopressin. Read More

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http://dx.doi.org/10.1016/j.cpcardiol.2017.12.002DOI Listing
July 2018
12 Reads