238 results match your criteria Current Rheumatology Reviews[Journal]


Novel Herbal Topical Patch containing Curcumin and Arnica Montana for the Treatment of Osteoarthritis.

Curr Rheumatol Rev 2019 Feb 14. Epub 2019 Feb 14.

Kota college of pharmacy, Kota, 325003, Rajasthan. India.

Background: Osteoarthritis (OA) ranks fifth among all forms of disability affecting 10% of the world population. Current treatments available are associated with multiple side effects and do not slow down the progression of disease. Moreover no such effective treatment is available till date in various systems of medicine to treat osteoarthritis. Read More

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http://dx.doi.org/10.2174/1573397115666190214164407DOI Listing
February 2019
1 Read

Evaluating the relationship between serum level of interleukin-6 and rheumatoid arthritis severity and disease activity.

Curr Rheumatol Rev 2019 Feb 6. Epub 2019 Feb 6.

Golestan Hospital Clinical Research Development Unit, Ahvaz Jundishapur University of Medical Sciences, Ahvaz. Iran.

Aim: The aim of this study was to evaluate the relationship between Interlukin-6 (IL-6) serum level and the severity and activity of RA.

Methods: In this cross-sectional study, 120 RA patients referred to the rheumatology clinic, the patients were diagnosed by rheumatologists according to ACR / EULAR 2010 criteria. Based on Based on DAS28 score the patients were divided into 4 groups: Remission, Mild, Moderate and Severe. Read More

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http://dx.doi.org/10.2174/1573397115666190206144223DOI Listing
February 2019
9 Reads

Maternal and Fetal Outcomes in Iranian Patients with Systemic Lupus Erythematosus: A Five Year Retrospective Study of 60 Pregnancies.

Curr Rheumatol Rev 2019 Jan 25. Epub 2019 Jan 25.

Department of OB and GYN, Shiraz University of Medical Sciences. Iran.

Background: As a multisystem autoimmune disease, systemic lupus erythematosus (SLE) mainly affects women during reproductive age. This retrospective study was designed to investigate the fetal and maternal outcomes of Iranian women with SLE.

Methods: Clinical and laboratory records of 60 pregnancies in 55 SLE patients who attended Hafez hospital, a tertiary referral center for high risk pregnancies and SLE patients affiliated with Shiraz University of Medical Science, were reviewed during April 2012 and March 2016. Read More

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http://dx.doi.org/10.2174/1573397115666190125162248DOI Listing
January 2019
3 Reads

Evaluation of Serum Calprotectin Level and Disease Activity in Patients with Rheumatoid Arthritis.

Curr Rheumatol Rev 2019 Jan 21. Epub 2019 Jan 21.

Shiraz Geriatric Research Center, Shiraz University of Medical Sciences, Shiraz. Iran.

Background: Rheumatoid arthritis (RA) is the most common type of chronic inflammatory arthritis with unknown etiology marked by a symmetric, peripheral polyarthritis. Calprotectin also can be used as a biomarker of disease activity in inflammatory arthritis and other autoimmune diseases.

Objective: In this study, we evaluated the association between serum calprotectin level and severity of RA activity. Read More

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http://www.eurekaselect.com/169226/article
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http://dx.doi.org/10.2174/1573397115666190122113221DOI Listing
January 2019
4 Reads

Patients Presenting with a Hot, Swollen Joint: a Single-Centre Retrospective Analysis.

Curr Rheumatol Rev 2019 Jan 21. Epub 2019 Jan 21.

Division of Trauma & Orthopaedics, Addenbrooke's Hospital, University of Cambridge, Cambridge, CB2 0QQ. United Kingdom.

A hot, swollen joint is a common clinical condition encountered in the ED and elective orthopaedic and rheumatology clinics. These patients can be difficult to manage and properly treat. The aim of this study was to report a single centre retrospective analysis of patients presenting to our institution for a hot, swollen joint over a three-month period. Read More

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http://dx.doi.org/10.2174/1573397115666190122113659DOI Listing
January 2019
6 Reads

Lifestyle Modification in Rheumatoid Arthritis: Dietary and Physical Activity Recommendations Based on Evidence.

Curr Rheumatol Rev 2019 Jan 21. Epub 2019 Jan 21.

Department of Nutrition and Dietetics, Faculty of Health Sciences, Beirut Arab University, P.O. Box 11-5020 Riad El Solh, Beirut. Lebanon.

Background: Rheumatoid arthritis is systemic autoimmune disease, considered the most common inflammatory articular disease among the general population. However not only the joints are affected; rheumatoid arthritis also has an extra-articular manifestation. As for many other chronic diseases, rheumatoid arthritis may be exacerbated by poorer lifestyle choices. Read More

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http://dx.doi.org/10.2174/1573397115666190121135940DOI Listing
January 2019
9 Reads

Immune checkpoint inhibitors-related rheumatic diseases: what rheumatologist should know?

Curr Rheumatol Rev 2019 Jan 18. Epub 2019 Jan 18.

Istinye University Faculty of Medicine, Liv Hospital, Department of Rheumatology, Istanbul. Turkey.

Immune checkpoint inhibitors are revolutionized drugs for cancer immunotherapy in the last years. The mechanism of action of CPIs including the limitation of the activation of T-cells, and thus enhancing the self-immune response against tumour cells. Checkpoint-inhibitors(CPIs) may dysregulate the immune system which resulting in some toxicities. Read More

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http://www.eurekaselect.com/169153/article
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http://dx.doi.org/10.2174/1573397115666190119094736DOI Listing
January 2019
24 Reads

Computer Modelling Of Wrist Biomechanics - Translation Into Specific Tasks.

Curr Rheumatol Rev 2019 Jan 18. Epub 2019 Jan 18.

Centre for Orthopaedic and Trauma Research Department of Orthopaedics and Trauma University of Adelaide Orthopaedic Surgeon Wakefield Orthopaedic Clinic, 270 Wakefield Street, Adelaide 5000. Australia.

Background: The carpus is a complicated and functionally challenged mechanical system and advancements in the understanding have been compromised by the recognition that there is no standard carpal mechanical system and no typical wrist. This paper cover component of a larger project that seeks to develop a kinetic model of wrist mechanics to allow reverse analysis of the specific biomechanical controls or rule of a specific patient's carpus, and then use those to create a forward mathematical model to reproduce the unique individual's anatomical motion based on the extracted rules.

Objective And Methods: Based on previous observations, the carpus essentially moves with only 2 degrees of freedom - pitch (flexion / extension) and yaw (radial deviation / ulnar deviation), while largely preventing roll (pronation / supination). Read More

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http://dx.doi.org/10.2174/1573397115666190119095311DOI Listing
January 2019
4 Reads

Assessment of Quality of Life in Systemic Lupus Erythematous Patients at a Tertiary Care Hospital in Egypt.

Curr Rheumatol Rev 2019 Jan 18. Epub 2019 Jan 18.

Public Health and Community Medicine Cairo University. Egypt.

Systemic lupus erythematosus (SLE) has a profound impact on quality of life.

Objective: The objective of this study was to explore the quality of life among Egyptian SLE patients and to assess its relationships with demographic and clinical features.

Methods: One hundred sixty-four SLE patients were recruited for this study. Read More

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http://dx.doi.org/10.2174/1573397115666190118144903DOI Listing
January 2019
5 Reads

Reinterpreting Evidence of Rheumatoid Arthritis-Associated Interstitial Lung Disease to Understand Etiology.

Curr Rheumatol Rev 2019 Jan 15. Epub 2019 Jan 15.

Center for Musculoskeletal Research, University of Rochester School of Medicine and Dentistry, Rochester, NY. United States.

Interstitial lung disease (ILD) is a well-known complication of rheumatoid arthritis (RA) which often results in significant morbidity and mortality. It is often diagnosed late in the disease process via descriptive criteria. Multiple subtypes of RA-ILD exist as defined by chest CT and histopathology [1]. Read More

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http://dx.doi.org/10.2174/1573397115666190116102451DOI Listing
January 2019
11 Reads

Scaphoid motion of the wrist with scapho-trapezio-trapezoidal osteoarthritis.

Curr Rheumatol Rev 2019 01 15. Epub 2019 Jan 15.

The University of Pittsburgh School of Medicine, Pittsburgh, PA, USA and Technion, Israel Institute of Technology, Haifa, Israel.

The purpose of this study was to investigate scaphoid motion within the scapho-trapezio-trapezoidal (STT) joint during wrist motion in the presence of STT joint osteoarthritis (OA). We studied 11 wrists with STT OA and 5 normal wrists. Computed tomography images were acquired in five wrist positions (maximum active flexion, extension, radial deviation, ulnar deviation, and neutral position). Read More

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http://dx.doi.org/10.2174/1573397115666190115125430DOI Listing
January 2019
2 Reads

Association between Human Leukocyte Antigens with Autoimmune Diseases: Diagnostic Approach.

Curr Rheumatol Rev 2019 Jan 15. Epub 2019 Jan 15.

Thalassemia and Hemoglobinopathy Research Center, Research Institute of Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz. Iran.

Background: The process of antigen presentation to immune cells is an undeniable contributor to pathogenesis of autoimmune diseases. Different studies have indicated several factors that are related to autoimmunity. Human leukocyte antigens (HLAs) are among such factors, which have a key role in autoimmunity because of their involvement in antigen presentation process. Read More

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http://dx.doi.org/10.2174/1573397115666190115143226DOI Listing
January 2019
5 Reads

Should the ultrasound of hands be a component ofrheumatoidarthritis remission criteria?

Curr Rheumatol Rev 2018 Dec 30. Epub 2018 Dec 30.

Rheumatology Department, University Hospital Center Hassan II Fez Faculty of Medicine, University Sidi Mohammed Ben Abdellah, Fez. Morocco.

Introduction: The definition of remission in rheumatoid arthritis (RA) is still difficult to determine. An ultrasound of the hands may be important in helping to confirm clinical remission. This study's aim was to evaluate the interest in using an ultrasound of the hands to confirm clinical remission, as well as comparing the various remission scores (DAS 28 VS, DAS 28 CRP, and SDAI) and the ultrasound data, in order to deduce the most accurate score to confirm this remission. Read More

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http://dx.doi.org/10.2174/1573397115666181231115233DOI Listing
December 2018
7 Reads

Preface.

Curr Rheumatol Rev 2019 ;15(1)

Case Western Reserve University School of Medicine Cleveland, OH, United States.

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http://dx.doi.org/10.2174/157339711501181212091724DOI Listing
January 2019
1 Read

Changes in Scaphoid and Lunate Position and Loading at Two Wrist Pushup Positions.

Curr Rheumatol Rev 2018 Dec 10. Epub 2018 Dec 10.

Department of Orthopedic Surgery, SUNY Upstate Medical University, Syracuse, New York. United States.

Background: Scapholunate interosseous ligament (SLIL) injury following a fall on an outstretched hand may lead to carpal instability and in some cases require long term rehabilitation following repair. Rehabilitation, especially in athletes, may include pushups, but little is known as to what type of pushup may be safer.

Objective: To determine biomechanical differences between two pushup position (neutral or extended). Read More

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http://dx.doi.org/10.2174/1573397115666181210170202DOI Listing
December 2018
10 Reads

Capitate and Lunate Morphology in Normal Wrist Radiographs-A Pilot study.

Curr Rheumatol Rev 2018 Dec 5. Epub 2018 Dec 5.

Department of Orthopedic Surgery, SUNY Upstate Medical University, Syracuse, NY. United States.

Morphology may provide the basis for the understanding of wrist mechanics. We used classification systems based on cadaver dissection of lunate and capitate types to evaluate a normal database of 70 wrist radiographs in 35 subjects looking for associations between bone shapes. Kappa statistics and a log-linear mixed -effects model with a random intercept were used. Read More

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http://dx.doi.org/10.2174/1573397115666181205165642DOI Listing
December 2018
2 Reads

Combination Therapy of Apremilast and Biologic Agent as a Safe Option of Psoriatic Arthritis and Psoriasis.

Curr Rheumatol Rev 2018 Nov 29. Epub 2018 Nov 29.

Department of Rheumatology , Covina Arthritis Clinic, Covina, CA. United States.

Psoriasis is a chronic immune-mediated inflammatory dermatologic condition that is often associated with psoriatic arthritis. There are multiple regimens for the treatment of psoriasis including disease modifying anti rheumatics drugs, biologic agents, phototherapy, topical retinoid and steroids creams, as well as apremilast. Apremilast is an oral phosphodiesterase inhibitor that was approved by the FDA in March 2014 for the treatment of psoriatic arthritis and September 2014 for the treatment of moderate to severe plaque psoriasis. Read More

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http://dx.doi.org/10.2174/1573397115666181130094455DOI Listing
November 2018
10 Reads

Body Mass Index Impact On Disease Activity, Clinical And Sonographic Remission Rates In Patients With Rheumatoid Arthritis.

Curr Rheumatol Rev 2018 Nov 30. Epub 2018 Nov 30.

Department of Internal Diseases, Faculty of Medicine, Medical University of Plovdiv; Plovdiv, Bulgaria; 2 Rheumatology Clinic, UMHAT 'Kaspela', Plovdiv. Bulgaria.

Aim: To investigate the impact of body mass index (BMI) on clinical disease activity indices and clinical and sonographic remission rates in patients with rheumatoid arthritis (RA).

Patients And Methods: Sixty-three patients with RA were categorized according to BMI score into three groups: normal (BMI<25), overweight (BMI 25-30) and obese (BMI≥30). Thirty-three of them were treated with conventional synthetic disease-modifying anti-rheumatic drugs (csDMARDs), and 30 with biologic DMARDs (bDMARDs). Read More

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http://dx.doi.org/10.2174/1573397115666181130143239DOI Listing
November 2018
3 Reads

Clinical Management of Medial Patellar Plica Syndrome: Expert Point of View from Diagnosis to Treatment

Curr Rheumatol Rev 2018 11 23. Epub 2018 Nov 23.

Department of Nutrition and Dietetics, Faculty of Health Sciences, Beirut Arab University, P.O. Box 11-5020 Riad El Solh, Beirut. Lebanon.

Synovial plicae are thickenings of the synovial knee membrane; they are very frequent and often asymptomatic. However, they can become symptomatic due to idiopathic or secondary causes, as trauma and inflammation of the synovial tissue. Currently, synovial plicae are classified as infrapatellar, mediopatellar and suprapatellar. Read More

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http://dx.doi.org/10.2174/1573397115666181123182633DOI Listing
November 2018
1 Read

Systemic lupus erythematosus and endothelial dysfunction: a close relationship.

Curr Rheumatol Rev 2018 Nov 25. Epub 2018 Nov 25.

Rheumatology and Clinical Immunolgy Unit, University and ASST Spedali Civili, Brescia. Italy.

Background: Accelerated atherosclerosis, responsible for premature cardiovascular disease, has been estimated to develop or progress in 10% of systemic lupus erythematosus (SLE) patients each year and to be 6-fold more frequent in SLE compared with the general population. The mechanisms underlying accelerated atherosclerosis in SLE are complex and involve classical and "non-classical" cardiovascular risk factors. Subclinical and disseminated atherosclerosis is associated with endothelial dysfunction and arterial stiffness. Read More

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http://www.eurekaselect.com/167721/article
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http://dx.doi.org/10.2174/1573397115666181126105318DOI Listing
November 2018
11 Reads

On the mechanisms of action of the low molecular weight fraction of commercial human serum albumin in osteoarthritis.

Curr Rheumatol Rev 2018 Nov 19. Epub 2018 Nov 19.

SomaLogic, Inc., 2945 Wilderness Place, Boulder, CO 80301. United States.

The low molecular weight fraction of commercial human serum albumin (LMWF5A) has been shown to successfully relieve pain and inflammation in severe osteoarthritis of the knee (OAK). LMWF5A contains at least three active components that could account for these anti-inflammatory and analgesic effects. We summarize in vitro experiments in bone marrow-derived mesenchymal stem cells, monocytic cell lines, chondrocytes, peripheral blood mononuclear cells, fibroblast-like synoviocytes, and endothelial cells on the biochemistry of anti-inflammatory changes induced by LMWF5A. Read More

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http://dx.doi.org/10.2174/1573397114666181119121519DOI Listing
November 2018
7 Reads

Helicobacter pylori infection in Sjögren's syndrome:Co-incidence or causality?

Curr Rheumatol Rev 2018 Nov 12. Epub 2018 Nov 12.

Joint, bone and connective tissue research center, Golestan University of medical Sciences, Gorgan. Iran.

Background And Aim: Lymphoid cell infiltration and destruction of exocrine glands, specifically lacrimal and salivary glands are characteristics of Sjogren's syndrome (SS). An etiological role has been proposed for Helicobacter pylori (H.Pylori), interacting in the clinical course and complications of SS (including gastric cancer and lymphoma). Read More

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http://dx.doi.org/10.2174/1573397114666181113102427DOI Listing
November 2018
12 Reads

Selenium and autoimmune diseases: a review article.

Curr Rheumatol Rev 2018 Oct 16. Epub 2018 Oct 16.

Rheumatic Diseases Research Center, Mashhad University of Medical Sciences, Mashhad. Iran.

Background: Selenium is an essential trace element with fundamental effects on human biology. Trace elements deficiency is not an uncommon finding in autoimmune diseases. This deficiency may be a consequence of autoimmune diseases or may contribute to their etiology. Read More

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http://dx.doi.org/10.2174/1573397114666181016112342DOI Listing
October 2018
47 Reads

Lower levels of vitamin D are associated with disease activity and low complement in Colombian patients with Systemic Lupus Erythematosus.

Curr Rheumatol Rev 2018 10 15. Epub 2018 Oct 15.

Rheumatology, Cell Immunology and Immunogenetics Group. School of Medicine Universidad de Antioquia, 67 Street # 53-108, Medellín. Colombia.

Background: Systemic Lupus Erythematosus [SLE] involves genetic, environmental, and hormonal alterations, including Vitamin D deficiency.

Objective: To evaluate the association between vitamin D levels with anti-dsDNA, complement proteins, immunoglobulins levels and disease activity scores Methods: A cross-sectional study was performed. The levels of 25-OH vitamin D were measured in patients older than 18 years with SLE according to ACR/97 [American College of Rheumatology 1997] from 2013 to 2015. Read More

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http://dx.doi.org/10.2174/1573397114666181015161547DOI Listing
October 2018
2 Reads

TMJ Arthritis Imaging: Conventional Radiograph Vs CT Scan - Is CT actually needed?

Curr Rheumatol Rev 2018 Sep 26. Epub 2018 Sep 26.

Department of Oral Pathology and Microbiology, Institute of Dental Sciences, Bhubaneswar, Odisha. India.

Purpose: The present study was conducted to evaluate the efficacy of conventional TMJ imaging in depicting osseous changes in mandibular condyle and glenoid fossa in patients with Rheumatoid arthritis and osteoarthritis by comparing the finding against CT and with an objective that if conventional TMJ imaging modality can appreciate the osseous changes in RA and OA then what is the need for CT scan. This further reducing the patient's radiation dose.

Materials And Method: A total of 70 patients (40 Rheumatoid Arthritis; 30 Osteoarthritis) were taken in the study aged between 40 - 60 years and divided in to age groups. Read More

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http://dx.doi.org/10.2174/1573397114666180927101637DOI Listing
September 2018
1 Read

The assessment of anxiety and depression and its associated factors in systemic lupus erythematosus.

Curr Rheumatol Rev 2018 Sep 25. Epub 2018 Sep 25.

University of Toronto Lupus Clinic, Toronto Western Hospital, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto, Ontario. Canada.

Depression and anxiety are common neuropsychiatric complaints in patients with systemic lupus erythematosus (SLE). While numerous studies have been performed to investigate the prevalence, impact, and associated factors of depression and anxiety, current literature presents mixed results as it pertains to a number of these topics. In particular, the prevalence varies substantially between studies due to methodological limitations, and heterogeneity in defining anxiety and depression, patient selection, and metrics used. Read More

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http://dx.doi.org/10.2174/1573397114666180926101513DOI Listing
September 2018
12 Reads

Evaluating the Effects of Oral N-Acetyl Cysteine on Inflammatory and Oxidative Stress Biomarkers in Rheumatoid Arthritis.

Curr Rheumatol Rev 2018 Sep 25. Epub 2018 Sep 25.

Department of Clinical Pharmacy, School of Pharmacy, Hamadan University of Medical Sciences, Hamadan. Iran.

Background: Rheumatoid arthritis (RA) is a common inflammatory disease of the joints. Due to importance of inflammation and oxidative stress in the pathogenesis of RA, drugs that have anti-oxidant and anti-inflammatory properties such as N-acetyl cysteine(NAC), can be effective as adjunctive therapy in patients with RA.

Aims: The aim of this study has been to evaluate the effects of oral NAC on inflammatory cytokines and oxidative stress in patients with RA. Read More

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http://dx.doi.org/10.2174/1573403X14666180926100811DOI Listing
September 2018
11 Reads

Prevalence of Subclinical Amyloidosis in a cross-sectional study of Egyptian RA Patients without proteinuria.

Curr Rheumatol Rev 2018 Sep 3. Epub 2018 Sep 3.

Dept. of Rheumatology, Al Azhar Univ, Cairo. Egypt.

Background: Amyloidosis is a life threatening complication of Rheumatoid Arthritis (RA) that should be detected as early as possible to avoid its morbidity and mortality.

Objective: To detect subclinical amyloidosis in RA patients without proteinuria and a disease duration more than 5 years.

Patients: Eighty-six RA patients seen between October 2013 and August 2014 were recruited for the study. Read More

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http://dx.doi.org/10.2174/1874471011666180903164014DOI Listing
September 2018
3 Reads

Post chikungunya chronic arthritis: a systemic inflammatory status triggering the acute coronary syndrome.

Curr Rheumatol Rev 2018 Aug 15. Epub 2018 Aug 15.

Dhruv Healthcare Multi-Speciality Hospital, Ahmedabad. India.

Background: Atherosclerosis and coronary plaque destabilization are linked to each other. Infections due to various microbes may trigger acute coronary syndrome (ACS) by systemic inflammation cascade.

Methods: We have evaluated the prevalence of Post chikungunya chronic arthritis (PCCA) among 400 consecutive ACS patients (Case group) and compared with control group subjected to elective surgery by the prospective case-control observational study. Read More

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http://dx.doi.org/10.2174/1573397114666180816112948DOI Listing
August 2018
6 Reads

The Role of Vascular Endothelial Growth Factor in Systemic Sclerosis.

Curr Rheumatol Rev 2018 Aug 9. Epub 2018 Aug 9.

Royal National Hospital for Rheumatic disease, Royal United Hospitals NHS Foundation Trusts, Bath. BA1 1RL . United Kingdom.

The pathological hallmarks of Systemic sclerosis (SSc) constitute an inter-related triad of autoimmunity, vasculopathy and tissue remodeling. Many signaling mediators have been implicated in SSc pathology; most focusing on individual components of this pathogenic triad and current treatment paradigms tend to approach management of such as distinct entities. The present review shall examine the role of vascular endothelial growth factor (VEGF) in SSc pathogenesis. Read More

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http://dx.doi.org/10.2174/1573397114666180809121005DOI Listing
August 2018
2 Reads

An Unusual Presentation of a Rare Scleroderma Mimic: What is Behind the Scenes?

Curr Rheumatol Rev 2018 08 7. Epub 2018 Aug 7.

Department of Clinical Pathology, Faculty of Medicine, Ain Shams University, El-Abaseya. Egypt.

Background: Scleroderma or systemic sclerosis (SSc) is a rare systemic autoimmune disease. Many conditions mimic the presentation of SSc, especially skin thickening and fibrosis. One of these conditions is scleredema, a rare collagen and mucin deposition disorder which was found to be associated with diabetes mellitus, streptococcal infection or monoclonal gammopathy. Read More

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http://dx.doi.org/10.2174/1573397114666180808091621DOI Listing
August 2018
11 Reads

The effect of neuropathic pain symptoms on remission in patients with early rheumatoid arthritis.

Curr Rheumatol Rev 2018 Aug 6. Epub 2018 Aug 6.

Department of Rheumatology, ASST Fatebenefratelli-Sacco, Milan. Italy.

Background: The presence of neuropatic pain (NeP) is common in subjects with established rheumatoid arthritis (RA), and it can influence the disease remission. These aspects have not been investigated in patients with early rheumatoid arthritis (ERA).

Objective: To investigate the effect of NeP on the achievement of remission in patients with ERA. Read More

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http://dx.doi.org/10.2174/1573397114666180806142814DOI Listing
August 2018
4 Reads

Neurological Involvement as the Initial Manifestation in Primary Sjögren's Syndrome.

Curr Rheumatol Rev 2018 Jul 30. Epub 2018 Jul 30.

GIRAT (Grupo de Investigacion en Reumatologia, Autoinmunidad y Medicina Traslacional) Fundacion Valle del Lili and Universidad Icesi, Cali. Colombia.

Background: Sjögren's syndrome is an autoimmune disease characterised by exocrinopathy mainly involving the salivary and lacrimal glands. In addition, it is a multisystemic condition (i.e. Read More

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http://dx.doi.org/10.2174/1573397114666180731101142DOI Listing
July 2018
4 Reads

Vasculitis: Decade in Review.

Curr Rheumatol Rev 2019 ;15(1):14-22

Department of Pediatrics, Division of Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey.

Background: In the last decade, we have come to better understand and manage the vasculitides. The classification of vasculitides has been revised. Genome- wide association studies and linkage analyses have been undertaken in hope of better understanding the pathogenesis of vasculitides. Read More

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http://www.eurekaselect.com/164038/article
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http://dx.doi.org/10.2174/1573397114666180726093731DOI Listing
January 2019
6 Reads

Metformin one in a million efficient medicines for rheumatoid arthritis complications: inflammation, Osteoblastogenesis, Cardiovascular disease, Malignancies.

Curr Rheumatol Rev 2018 Jul 17. Epub 2018 Jul 17.

Golestan Hospital Clinical Research Development Unit, Ahvaz Jundishapur University of Medical Sciences, Ahvaz. Iran.

Background: Rheumatoid arthritis is a widespread autoimmune disease and inflammation and bone destruction are two main issues in rheumatoid arthritis.

Objective: To discussing metformin effects on rheumatoid arthritis complications.

Method: We conducted a narrative literature search including clinical trials, experimental studies on laboratory animals and cell lines. Read More

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http://dx.doi.org/10.2174/1573397114666180717145745DOI Listing
July 2018
7 Reads

Osteoarthritis - Current Insights in Pathogenesis, Diagnosis and Treatment.

Curr Rheumatol Rev 2018 ;14(2):91-97

Department of Rheumatology and Clinical Immunology Justus-Liebig University Giessen Kerckhoff Clinic, Bad Nauheim, Germany.

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http://dx.doi.org/10.2174/157339711402180706144757DOI Listing
January 2018
1 Read

High levels of serum uric acid, cystain C and lipids concentration and their clinical significance in primary gouty arthritis patients.

Curr Rheumatol Rev 2018 07 4. Epub 2018 Jul 4.

Department of Rheumatology, North Sichuan Medical College, 63 Wenhua Road, Nanchong, 637007, Sichuan China.

Objective: To investigate the changes of serum uric acid (sUA), lipids and cystatin C (CysC) in primary gout patients, and to explore the clinical significance in gout patients.

Methods: sUA, CysC, high-sensitivity C-reactive protein (hsCRP) and other biochemical parameters were measured in 326 gout patient and 210 healthy control subjects, blood cell counts were also detected. Clinical data were collected from gout patients. Read More

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http://dx.doi.org/10.2174/1573397114666180705095625DOI Listing
July 2018
1 Read

Association of Serum Homocysteine Level and Interstitial Lung Disease in Systemic Sclerosis: A Case-control Study.

Curr Rheumatol Rev 2019 ;15(1):74-78

Endocrine and Metabolism Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

Background: Systemic sclerosis is a disorder of connective tissue with unknown cause, affecting the skin and internal organs, characterized by fibrotic changes.

Objective: To determine the correlation between serum homocysteine level and interstitial lung involvement in systemic sclerosis.

Materials And Methods: In this case - control study, 59 patients who fulfilled the ACR/EULAR classification criteria for systemic sclerosis and were referred to Hafez Hospital of Shiraz, Iran, were included as the case group. Read More

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http://dx.doi.org/10.2174/1573397114666180628162907DOI Listing
January 2019
1 Read

Self-reported Instability in Knee Osteoarthritis: A Scoping review of Literature.

Curr Rheumatol Rev 2018 Jun 27. Epub 2018 Jun 27.

Department of Physiotherapy, School of Allied Health Sciences, Manipal Academy of Higher Education, Manipal, Karnataka. India.

Knee Osteoarthritis (OA) is a disabling musculoskeletal condition among the elderly. Self-reported instability is one of the impairments associated with osteoarthritis. A complete understanding of the self-reported instability in knee OA is essential, to identify the best strategies for overcoming this impairment. Read More

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http://dx.doi.org/10.2174/1573397114666180628111858DOI Listing
June 2018
6 Reads

Genetics and Epigenetics Mechanism in the Pathogenesis of Behçet's Disease.

Curr Rheumatol Rev 2019 ;15(1):7-13

Department of Biological and Biomedical Sciences, the Aga Khan University Hospital, Karachi, Pakistan.

Background: Behçet's Disease (BD) is characterized by numerous systemic manifestations and is known for its ability to affect both, arteries and the veins. However, the etiology of BD is only partially understood, and previous studies have demonstrated a role for genetic and epigenetic factors that contribute to disease pathophysiology. Several studies have implicated T cells and monocytes in the pathogenesis of BD especially when these cells are stimulated by heat shock proteins and streptococcal antigen. Read More

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http://dx.doi.org/10.2174/1573397114666180521090335DOI Listing
January 2019
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Characteristics and Outcomes of Patients with Anti-Glomerular Basement Membrane Antibody Disease and Anti-Neutrophil Cytoplasmic Antibodies.

Curr Rheumatol Rev 2018 05 16. Epub 2018 May 16.

Division of Nephrology, University of Washington School of Medicine, Seattle, Washington. United States.

Background: It is unclear whether patients with anti-glomerular basement membrane (GBM) disease and anti-neutrophil cytoplasmic antibodies (ANCA), so called "double-positive" (DP), have a different clinical presentation and outcome compared to patients with anti-GBM antibody disease alone. This study describes the clinical and histologic characteristics as well as the patient and renal outcomes of DP patients at the University of Washington compared to patients with anti-GBM antibody disease alone.

Methods: Adults admitted to the University of Washington and Harborview Medical Centers from 2000 to 2016 who had a kidney biopsy showing anti-GBM disease characterized by crescentic glomerulonephritis with strong linear staining of glomerular basement membranes for IgG by immunofluorescence were included. Read More

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http://dx.doi.org/10.2174/1573397114666180516131240DOI Listing
May 2018
3 Reads

Subtypes of Antiphospholipid Antibodies in Neurologic Disorders: An Observational Study.

Curr Rheumatol Rev 2019 ;15(1):59-66

School of Medicine, Mashhad, Iran.

Background And Objectives: Concomitant neurologic manifestations and positive antiphospholipid antibodies (APAs) have been investigated in different manners. The present study aimed to investigate the association between neurologic manifestations and APAs.

Materials And Methods: This cross-sectional descriptive study was conducted on 100 consecutive patients with selected neurological manifestations and at least one positive APAs within the age range of 20-50 years, referred to the Rheumatic Diseases Research Center from the Northeast Central Neurology Department of Iran during August 2012 to March 2014. Read More

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http://dx.doi.org/10.2174/1573397114666180514125412DOI Listing
January 2019
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Risk Factors Associated With Musculoskeletal Injury: A Prospective Study of British Infantry Recruits.

Curr Rheumatol Rev 2019 ;15(1):50-58

Medical Centre & Rehabilitation Department, Defence Primary Healthcare, Infantry Training Centre Catterick Garrison, DL9 3PS, United Kingdom.

Background: Musculoskeletal Injury (MSKI), a common problem in both military and physically active civilian populations, has been suggested to result from both extrinsic and intrinsic factors.

Objective: To investigate prospectively whether gait biomechanics, aerobic fitness levels and smoking status as well as entry military selection test variables can be used to predict MSKI development during recruit training.

Methods: British infantry male recruits (n = 562) were selected for the study. Read More

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http://dx.doi.org/10.2174/1573397114666180430103855DOI Listing
January 2019
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Gauzoma in A Scleroderma Patient Following Open Heart Surgery: A Case Report.

Curr Rheumatol Rev 2019 ;15(1):79-81

Department of Internal Medicine, Division of Rheumatology, Shiraz University of Medical Sciences, Shiraz, Iran.

Introduction: Gauzoma is an iatrogenic complication which occurs rarely due to surgical team negligence. Depending on the sterility of the retained tissue, it can lead to life threatening surgical complications or may remain asymptomatic for many years and be detected incidentally in imaging studies. It may be mistaken as tumors or aneurysms. Read More

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http://dx.doi.org/10.2174/1573397114666180423104410DOI Listing
January 2019
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Juvenile Scleroderma-What has Changed in the Meantime?

Curr Rheumatol Rev 2018 ;14(3):219-225

Department of Pediatric Rheumatology, Cerrahpasa Medical School, Istanbul University, Istanbul, Turkey.

Background: Juvenile scleroderma is a rarely seen chronic connective tissue disorder characterized by stiffening of the skin. The frequency of the disease was reported as one per million. According to organ involvement, the disease is divided into two main forms: systemic and localized scleroderma. Read More

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http://dx.doi.org/10.2174/1573397114666180423105056DOI Listing
January 2019
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Musculoskeletal manifestations of sarcoidosis: A review article.

Curr Rheumatol Rev 2018 Apr 24. Epub 2018 Apr 24.

Department of Rheumatology, Rheumatic Diseases Research Center, Mashhad University of Medical Sciences, Mashhad. Iran.

Sarcoidosis is a multisystem inflammatory disease with an etiology that is not clearly understood. Amongst the different organs that may be affected, the lungs are the most common. Musculoskeletal manifestations of the disease are uncommon. Read More

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http://www.eurekaselect.com/161541/article
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http://dx.doi.org/10.2174/1573397114666180425111901DOI Listing
April 2018
4 Reads

Flipped Learning: Can Rheumatology Lead the Shift in Medical Education?

Curr Rheumatol Rev 2019 ;15(1):67-73

Department Rheumatology and Rehabilitation, Ain Shams University, School of Medicine, Al Waili, Egypt.

Objective: To 1. implement flipped classroom rheumatology teaching for undergraduate education. 2. Read More

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http://dx.doi.org/10.2174/1573397114666180416170156DOI Listing
January 2019
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Clinico-epidemiological Study of Morphea from a Tertiary Care Hospital.

Curr Rheumatol Rev 2018 ;14(3):251-254

Department of Dermatology, STDs and Leprosy, Jawaharlal Nehru Medical College (JNMC), Aligarh Muslim University (AMU), Aligarh, India.

Introduction: Morphea is an uncommon disease that presents with skin induration and sclerosis. The disease is common in Caucasians and there are few studies describing the clinicoepidemiological profile of these patients from the Indian subcontinent.

Methods: This prospective study was conducted during a three year period from June 2014 to May 2017. Read More

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http://dx.doi.org/10.2174/1573397114666180410115553DOI Listing
January 2019
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Future Perspectives in the Diagnosis of Neuropsychiatric Lupus by Advanced Magnetic Resonance Imaging Techniques.

Curr Rheumatol Rev 2018 ;14(3):213-218

Department of Autoimmune Diseases, Hospital Clinic, Barcelona, Catalonia, Spain.

Neuropsychiatric (NP) syndromes are an important cause of morbi-mortality in patients with Systemic Lupus Erythematosus (SLE). Despite remarkable recent progress, there are no definite methods to diagnose neuropsychiatric SLE (NPSLE) or to differentiate primary NPSLE from secondary causes. NPSLE remains a diagnosis of exclusion, and the clinical judgment is still the main approach to the correct diagnosis. Read More

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http://www.eurekaselect.com/161180/article
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http://dx.doi.org/10.2174/1573397114666180411093655DOI Listing
January 2019
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Adenosine Deaminase Activity and HLA-DRB as Diagnostic Markers for Rheumatoid Arthritis.

Curr Rheumatol Rev 2019 ;15(1):44-49

Department of Rheumatology, Medical Sciences University of Birjand, Birjand, Iran.

Background: Rheumatoid Arthritis (RA) is a chronic multi systemic disorder with the unclarified ethiopathology. Although several markers have been presented for recognition of RA, but none of them has been specific. New markers such as HLA typing and activity of Adenosine Deaminase (ADA) isoenzymes could be useful and specific. Read More

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http://dx.doi.org/10.2174/1573397114666180406101239DOI Listing
January 2019
4 Reads