225 results match your criteria Current Pediatric Reviews[Journal]


Testing an ectoin containing emollient for atopic dermatitis.

Curr Pediatr Rev 2019 Apr 15. Epub 2019 Apr 15.

Department of Paediatrics, The Chinese University of Hong Kong, Shatin. Hong Kong.

Aim: To describe the methodology in studying patient's acceptability and efficacy of an ectoin containing emollient for atopic dermatitis (AD) Methods: We described the methodology that we used in studying emollients and moisturizers, and patient acceptability of a group of AD patients before and following usage of an ectoin-containing proprietary emollient. These data were also compared with other emollients that we previously reported.

Results: 30 subjects (50% Male, Mean (SD) age: 9. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396315666190415144244DOI Listing
April 2019
1 Read

An Approach to the Diagnostic Challenges of Tree Nut Allergy.

Curr Pediatr Rev 2019 ;15(1):2-3

Texas Children's Hospital Division of Immunology, Allergy and Rheumatology, Houstan, TX, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/157339631501190405120050DOI Listing
January 2019

Preface.

Curr Pediatr Rev 2019 ;15(1)

Department of Molecular and Developmental Medicine, University of Siena, Siena, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/157339631501190405115626DOI Listing
January 2019

Microbiological Diagnosis of Skeletal System Infections in Children.

Authors:
Pablo Yagupsky

Curr Pediatr Rev 2019 Apr 8. Epub 2019 Apr 8.

Clinical Microbiology Laboratory, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva 84101. Israel.

Background: If not timely diagnosed and adequately treated, skeletal system infections in children may result in severe and permanent disability. Prompt identification of the etiology of the disease and determination of its antibiotic susceptibility is crucial for the successful management of septic arthritis, osteomyelitis, and spondylodiscitis. However, the bacteriological diagnosis of these infections has been traditionally limited by the low yield of conventional cultures and, on average, one-third of cases of pediatric joint and bone infections remained unconfirmed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396315666190408114653DOI Listing
April 2019
2 Reads

Cardiac Murmurs In Children: A Challenge For The Primary Care Physician.

Curr Pediatr Rev 2019 Mar 20. Epub 2019 Mar 20.

Department of Paediatrics, University of Patras Medical School, Patras. Greece.

Congenital heart disease is present in almost 1% of live births and despite current progress in prenatal screening a significant percentage has delayed diagnosis or remain undiagnosed. A cardiac murmur may be the first or unique clinical sign of congenital heart disease in childhood, however less than 1% of auscultated murmurs are of organic cause. Distinguishing between an innocent and a pathologic murmur can be challenging and the experience of the examiner is crucial for identifying the distinctive properties of an innocent murmur. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396315666190321105536DOI Listing
March 2019
7 Reads

Herpes zoster onset 9 years after first varicella zoster vaccination in a 11 year old child - a case report.

Curr Pediatr Rev 2019 Mar 18. Epub 2019 Mar 18.

Department of Pediatrics, University General Hospital of Patras. Greece.

Background: Herpes zoster (HZ) tends to affect the elderly population and immunocompromised younger patients. However, HZ cases in healthy children have also been reported.

Objective: This paper is a reminder to physicians, that Herpes Zoster can still present in children, even in the era after the development of the varicella vaccine and its introduction in the national immunization programs globally. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396315666190318163927DOI Listing
March 2019
1 Read

Pica: A common condition that is commonly missed - An update review.

Curr Pediatr Rev 2019 Mar 13. Epub 2019 Mar 13.

Department of Paediatrics, The Chinese University of Hong Kong, Shatin. Hong Kong.

Background: Pica is a common condition in childhood that is commonly missed.

Objective: To familiarize physicians with the clinical evaluation and management of children with pica.

Methods: A PubMed search was completed in Clinical Queries using the key term "pica" OR "dirt-eating". Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396315666190313163530DOI Listing
March 2019
3 Reads

New Nutritional And Terapeutical Strategies Of Nec.

Curr Pediatr Rev 2019 Mar 13. Epub 2019 Mar 13.

Pediatric Department for the Treatment and Study of abdominal Disease and Abdominal Transplants, ISMETT-UPMC, Palermo . Italy.

Necrotizing enterocolitis (NEC) is a multifactorial disorder that primarily affects premature infants. Several feeding practices, such as type of feeding (human milk versus formula feeding), timing of enteral feeding initiation and flux of enteral feeding have been investigated so far in order to prevent NEC. However, currently well-established and shared clinical nutritional practices are not available in preventing NEC. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396315666190313164753DOI Listing
March 2019
5 Reads

Necrotizing Enterocolitis: Long Term Complications.

Curr Pediatr Rev 2019 Mar 11. Epub 2019 Mar 11.

University of Florida Department of Pediatrics Division of Neonatology Address: 1600 SW Archer Road Gainesville, Florida. United States.

Necrotizing enterocolitis (NEC) remains the most threatening gastrointestinal complication of prematurity leading to a high mortality, morbidity and cost. Common complications of NEC include neurodevelopmental delay, failure to thrive, gastrointestinal problems including strictures and adhesions, cholestasis, short bowel syndrome with or without intestinal failure that can be difficult to manage. Infants who develop NEC benefit from close follow-up for early diagnosis and treatment of complications. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396315666190312093119DOI Listing

Tinea Imbricata: An Overview.

Curr Pediatr Rev 2019 Feb 7. Epub 2019 Feb 7.

Department of Pediatrics and Department of Dermatology and Skin Sciences, The University of British Columbia, Vancouver, British Columbia. Canada.

Background: Tinea imbricata is a chronic superficial mycosis caused exclusively by Trichophyton concentricum. The condition mainly affects individuals living in primitive and isolated environment in developing countries and is rarely seen in developed countries. Physicians in nonendemic areas might not be aware of this fungal infection. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396315666190207151941DOI Listing
February 2019
1 Read

Role of Breathing Exercises And Yoga/Pranayam In Childhood Asthma: A Systematic Review.

Curr Pediatr Rev 2019 Jan 21. Epub 2019 Jan 21.

Department of Pediatrics, All India Institute of Medical Sciences, New Delhi. India.

Background: Various complementary or alternative medicines (including breathing exercises and yoga/pranayama) have been tried as an attractive option to pharmacotherapy in childhood asthma.

Objective: To evaluate the role of breathing exercise and yoga/pranayama as add on therapy to the "pharmacologically recommended treatment" of childhood asthma.

Methods: We searched the published literature through the major databases: Medline via Ovid, PubMed, CENTRAL, Embase, and Google Scholar till June 2018. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396315666190121122452DOI Listing
January 2019
7 Reads

Antimicrobial Stewardship in the Neonatal Intensive Care Unit: An Update.

Curr Pediatr Rev 2019 ;15(1):47-52

Department of Paediatrics, Patras Medical School, Patras, Greece.

Neonates represent a vulnerable population for infections and neonatal sepsis is a major cause of mortality and morbidity worldwide. Therefore, antimicrobials are the most commonly prescribed drugs in the Neonatal Intensive Care Unit Setting but unfortunately are quite often used inappropriately with various short and long-term effects. The rational use of antimicrobials is of paramount importance in this population and structured antimicrobial stewardship interventions should be in place. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396315666190118101953DOI Listing
January 2019
2 Reads

"The Compromised Fetal and Neonatal Lives and their Possible Long-term Consequences".

Authors:
Oreste Battisti

Curr Pediatr Rev 2018 ;14(4):211

Emeritus Academic Professor Oreste Battisti, University of Liege (Belgium) And Catholic University of Bukavu, Congo.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/157339631404181221092046DOI Listing
January 2019
1 Read

The role of probiotics in the prevention of necrotizing enterocolitis.

Curr Pediatr Rev 2018 Dec 24. Epub 2018 Dec 24.

Children's Hospital Zagreb, Zagreb. Croatia.

Necrotizing enterocolitis (NEC) is a frequent and severe life-threatening disease affecting the gastrointestinal tract of preterm infants. Given that NEC occurs in a well-defined population of patients, there might be a considerable benefit in identifying specific pharmacological and nutritional preventive strategies, that could reduce the incidence of NEC. Amongst nutritional strategies emphasis has been put on the use of probiotics. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396315666181224123223DOI Listing
December 2018
1 Read

Non-transplant surgical management of short bowel syndrome in children: an overview.

Curr Pediatr Rev 2018 Nov 29. Epub 2018 Nov 29.

University of Florence, Meyer Children's Hospital, Florence. Italy.

Management of severe Short Bowel Syndrome (SBS) is still one of the largest challenges of the medicine. Vast majority of the short bowel patients are children, the conditions that lead to this possible outcome most often are necrotizing enterocolitis (NEC), small intestinal volvulus as a result of intestinal malrotation, gastroschisis and the "apple peel" syndrome. Therefore paediatricians and paediatric surgeons face this challenge most often. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396315666181129164112DOI Listing
November 2018
14 Reads

Long Term Outcome Of Infants With Nec.

Curr Pediatr Rev 2018 Nov 30. Epub 2018 Nov 30.

Pediatric surgery Unit - INFERMI Hospital- Rimini. Italy.

Necrotizing enterocolitis (NEC) is a significant complication for premature newborns. Infants who survive NEC are at increased risk of having poor long-term physiological and neurodevelopmental growth. The objective of this paper is to give a comprehensive description of the long-term consequences of NEC. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396315666181130144925DOI Listing
November 2018
17 Reads

Human Breast Milk-acquired Cytomegalovirus Infection: Certainties, Doubts and Perspectives.

Curr Pediatr Rev 2019 ;15(1):30-41

Neonatal Intensive Care Unit, Neonatal Pathology and Neonatal Section, AOU and University of Cagliari, Italy.

Breast Milk (BM) is the best source of nutrition for newborns, especially if premature. In fact, its beneficial impact on short- and the long-term neonatal outcome has was deeply described. Unfortunately, BM could not be always so safe, especially due to the possible presence of maternal viruses that can be shed and transferred to the breastfed neonate. Read More

View Article

Download full-text PDF

Source
http://www.eurekaselect.com/167722/article
Publisher Site
http://dx.doi.org/10.2174/1573396315666181126105812DOI Listing
January 2019
17 Reads

Bone Manifestation of Faulty Perinatal Hormonal Imprinting: A Review.

Authors:
G Csaba

Curr Pediatr Rev 2019 ;15(1):4-9

Department of Genetics, Cell and Immunobiology, Semmelweis University, Budapest, Hungary.

Hormonal imprinting takes place at the first encounter between the developing receptor and its target hormone and the encounter determines the receptor's binding capacity for life. In the critical period of development, when the window for imprinting is open, the receptor can be misdirected by related hormones, synthetic hormones, and industrial or communal endocrine disruptors which cause faulty hormonal imprinting with life-long consequences. Considering these facts, the hormonal imprinting is a functional teratogen provoking alterations in the perinatal (early postnatal) period. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396315666181126110110DOI Listing
January 2019
1 Read

Childhood Solitary Cutaneous Mastocytoma: Clinical Manifestations, Diagnosis, Evaluation, and Management.

Curr Pediatr Rev 2019 ;15(1):42-46

Pediatric Institute, Kuala Lumpur General Hospital, Kuala Lumpur, Malaysia.

Background: The diagnosis of solitary cutaneous mastocytoma is mainly clinical, based on lesion morphology, the presence of a positive Darier sign, and the absence of systemic involvement. Knowledge of this condition is important so that an accurate diagnosis can be made.

Objective: To familiarize physicians with the clinical manifestations, diagnosis, evaluation, and management of a solitary cutaneous mastocytoma. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396315666181120163952DOI Listing
January 2019
16 Reads

What is New in Food Allergy?

Curr Pediatr Rev 2018 ;14(3):138

Associate Professor of Pediatric Allergy Food Immunotherapy Program Director Immunology, Allergy and Rheumatology Texas Children's Hospital Baylor College of Medicine Houston, Texas, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/157339631403181107154212DOI Listing
December 2018
10 Reads

The Unlicensed and Off-label Prescription of Medications in General Paediatric Ward: An Observational Study.

Curr Pediatr Rev 2019 ;15(1):62-66

Department of Paediatrics, Hospital De Clínicas De Porto Alegre, Porto Alegre, Brazil.

Background: Unlicensed (UL) and Off-label (OL) prescription of medications is common in paediatrics and does not constitute negligent practice since there is often no approved alternative according to FDA bulary.

Aim: The study aimed to determine the current frequency of UL and OL prescriptions in children from one month to 12 years of age in a Paediatric Inpatient Unit (PIU).

Methods: This is an observational, prospective study, reviewing the prescriptions of all patients admitted to the PIU in a university hospital in a single week in August 2014 and a single week in January 2015. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396314666181113101506DOI Listing
January 2019
19 Reads

Breath-Holding Spells in Pediatrics: A Narrative Review of the Current Evidence.

Curr Pediatr Rev 2019 ;15(1):22-29

Department of Paediatrics, The Chinese University of Hong Kong, Shatin, Hong Kong.

Background: Breath-holding spells are common, frightening, but fortunately benign events. Familiarity with this condition is important so that an accurate diagnosis can be made.

Objective: To familiarize physicians with the clinical manifestations, diagnosis, evaluation, and management of children with breath-holding spells. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396314666181113094047DOI Listing
January 2019
4 Reads

Alpha1-Antitrypsin Deficiency: Transition of Care for the Child With AAT Deficiency into Adulthood.

Curr Pediatr Rev 2019 ;15(1):53-61

Division of Pediatric Gastroenterology, Hepatology and Nutrition MUSC Children's Hospital, South Carolina, SC, United States.

Importance: Alpha1-antitrypsin (AAT) deficiency is a common, but an underdiagnosed genetic condition, affecting 1 in 1500 individuals. It can present insidiously with liver disease in children. Although clinical practice guidelines exist for the management of AAT deficiency, especially with regards to pulmonary involvement, there are no published recommendations that specifically relate to the management of the liver disease and monitoring for lung disease associated with this condition, particularly in children. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396314666181113094517DOI Listing
January 2019
31 Reads

Tall Stature: A Challenge for Clinicians.

Curr Pediatr Rev 2019 ;15(1):10-21

Department of Internal Medicine and Therapeutics, Pediatrics and Adolescent Care Unit, University of Pavia, Strada Nuova 65, 27100 Pavia, Italy.

Clinicians generally use the term "tall stature" to define a height more than two standard deviations above the mean for age and sex. In most cases, these subjects present with familial tall stature or a constitutional advance of growth which is diagnosed by excluding the other conditions associated with overgrowth. Nevertheless, it is necessary to be able to identify situations in which tall stature or an accelerated growth rate indicate an underlying disorder. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396314666181105092917DOI Listing
January 2019
1 Read

Pathophysiology of Necrotizing Enterocolitis: An Update.

Curr Pediatr Rev 2018 Nov 2. Epub 2018 Nov 2.

University of Florida Department of Pediatrics Division of Neonatology Address: 1600 SW Archer Road Gainesville, Florida. United States.

NEC is a devastating disease that, once present, is very difficult to treat. In the absence of an etiologic treatment, preventive measures are required. Advances in decoding the pathophysiology of NEC are being made but a more comprehensive understanding is needed for the targeting of preventative strategies. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396314666181102123030DOI Listing
November 2018
16 Reads

Management of NEC: surgical treatment and role of traditional X-ray versus Ultrasound imaging, experience of a single centre.

Curr Pediatr Rev 2018 Nov 2. Epub 2018 Nov 2.

Department of Surgery, Santobono-Pausilipon Children Hospital, Napoli. Italy.

Necrotizing enterocolitis is the most common cause of the postnatal critical conditions and remains one of the dominant cause of newborns' death in Neonatal Intensive Care. The morbidity and mortality associated with necrotizing enterocolitis remains largely unchanged and the incidence of necrotizing enterocolitis continues to increase. There is no general agreement regarding the surgical treatment of the necrotizing enterocolitis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396314666181102122626DOI Listing
November 2018
2 Reads

A Cross-sectional Study of Two Chemotherapy Protocols on Long Term Neurocognitive Functions in Egyptian Children Surviving Acute Lymphoblastic Leukemia.

Curr Pediatr Rev 2018 ;14(4):253-260

Pediatric Oncology Unit, Faculty of Medicine, Zagazig University, Zagazig, Egypt.

Introduction: Subtle neurocognitive deficits have been recently observed in Acute Lymphoblastic Leukemia (ALL) survivors.

Aim: We aim to assess the neurocognitive functions of ALL survivors who had been treated with chemotherapy only using two different protocols, and to identify treatment-related risk factors.

Patients And Methods: We carried a multicenter study involving 3 pediatric oncology centers on 100 children who were treated for ALL. Read More

View Article

Download full-text PDF

Source
http://www.eurekaselect.com/166816/article
Publisher Site
http://dx.doi.org/10.2174/1573396314666181031134919DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416189PMC
January 2019
19 Reads

Iron Bisglycinate Chelate and Polymaltose Iron for the Treatment of Iron Deficiency Anemia: A Pilot Randomized Trial.

Curr Pediatr Rev 2018 ;14(4):261-268

Kilyos Assessoria, Consultoria, Cursos e Palestras, Sao Paulo, 01311-100, Brazil.

Background: Iron Deficiency Anemia (IDA) is a major public health problem worldwide. Iron Bisglycinate Chelate (FeBC) and polymaltose iron (FeP) are used for the treatment of IDA and exhibit good tolerability with a low incidence of adverse effects. However, these compounds have important differences in their structures and bioavailability. Read More

View Article

Download full-text PDF

Source
http://www.eurekaselect.com/165885/article
Publisher Site
http://dx.doi.org/10.2174/1573396314666181002170040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416187PMC
January 2019
9 Reads

The Therapeutic Potential of Stem Cells for Bronchopulmonary Dysplasia: "It's About Time" or "Not so Fast" ?

Curr Pediatr Rev 2018 ;14(4):227-238

Division of Neonatology, Department of Pediatrics, Children's Hospital of Eastern Ontario (CHEO) and CHEO Research Institute, Ottawa, ON, Canada.

Objective: While the survival of extremely premature infants has improved over the past decades, the rate of complications - especially for bronchopulmonary dysplasia (BPD) - remains unacceptably high. Over the past 50 years, no safe therapy has had a substantial impact on the incidence and severity of BPD.

Methods: This may stem from the multifactorial disease pathogenesis and the increasing lung immaturity. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396314666180911100503DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416190PMC
January 2019
9 Reads

Hydrops Fetalis and THE Parvovirus B-19.

Curr Pediatr Rev 2018 ;14(4):239-252

Department of Obstetrics and Gynecology, Democritus University of Medicine in Thrace, Konotin, Greece.

Definition: Hydrops Fetalis (HF) or fetal hydrops is identified as an abnormal interstitial collection of fluid in at least 2 or more compartments of the fetal torso (peritoneal cavity, pleura, and pericardium). An alternative definition discusses about liquor accumulation in two fetal anatomical areas or an effusion in one site and anasarca.

Background: Parvovirus B-19 is a common childhood illness; the virus can cause fetal anemia, non-immune fetal hydrops, and spontaneous abortion and might lead to fetal demise. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396314666180820154340DOI Listing
January 2019
19 Reads

Preterm Birth: Long Term Cardiovascular and Renal Consequences.

Curr Pediatr Rev 2018 ;14(4):219-226

Medecine Neonatale, Hopital La Conception, APHM, Aix-Marseille Universite, Marseille, France.

Background: Cardiovascular and chronic kidney diseases are a part of noncommunicable chronic diseases, the leading causes of premature death worldwide. They are recognized as having early origins through altered developmental programming, due to adverse environmental conditions during development. Preterm birth is such an adverse factor. Read More

View Article

Download full-text PDF

Source
http://www.eurekaselect.com/164626/article
Publisher Site
http://dx.doi.org/10.2174/1573396314666180813121652DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416185PMC
January 2019
9 Reads

The Acutely Traumatized Child: Advances and Opportunities.

Authors:
Rodrick Lim

Curr Pediatr Rev 2018 ;14(1)

Associate Professor of Pediatrics Department of Pediatric and Medicine Site Chief Children`s Hospital Emergency Department at LHSC Schulich School of Medicine & Dentistry London, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/157339631401180718111811DOI Listing
January 2018
1 Read

Preface.

Curr Pediatr Rev 2018 ;14(1)

Department of Molecular and Developmental Medicine University of Siena Siena, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/157339631401180718111554DOI Listing
January 2018
2 Reads

Neonatal and Long-Term Consequences of Fetal Growth Restriction.

Curr Pediatr Rev 2018 ;14(4):212-218

University Paris Diderot, Sorbone Paris-Cite, Inserm U1141, Neonatal intensive care unit, Assistance Publique- Hopitaux de Paris, Robert Debre Children's hospital, Paris, France.

Background: Fetal Growth Restriction (FGR) is one of the most common noxious antenatal conditions in humans, inducing a substantial proportion of preterm delivery and leading to a significant increase in perinatal mortality, neurological handicaps and chronic diseases in adulthood. This review summarizes the current knowledge about the postnatal consequences of FGR, with a particular emphasis on the long-term consequences on respiratory, cardiovascular and neurological structures and functions.

Result And Conclusion: FGR represents a global health challenge, and efforts are urgently needed to improve our understanding of the critical factors leading to FGR and subsequent insults to the developing organs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396314666180712114531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416241PMC
January 2019
8 Reads

Atopic Dermatitis and Food Allergy: A Paediatric Approach.

Curr Pediatr Rev 2018 ;14(3):171-179

Guy's and St. Thomas' NHS Foundation Trust, Westminster Bridge Road, London, SE1 7EH, United Kingdom.

Atopic dermatitis and food allergy are common conditions of childhood that are closely linked. 30% of children with moderate to severe eczema suffer from food allergy and can present with different types of reactions: immediate or IgE-mediated reactions, delayed or non-IgEmediated eczematous flares, or a combination of the two. A detailed history is very important when approaching such patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396314666180613083616DOI Listing
December 2018
18 Reads

Special Traumatized Populations: Burns Injuries.

Curr Pediatr Rev 2018 ;14(1):64-69

Department of Pediatrics, Schulich School of Medicine, Western University, London, Ontario, Canada.

Background: It is important for physicians treating children to be aware of unique presentations that require expertise and knowledge. One area of importance when caring for traumatized children is Thermal Burn Injuries. Burns commonly result in morbidity in children; as such, the appropriate identification of the severity of the burn and appropriate management are integral to minimize the complications of burns during the acute phase. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396314666180608095033DOI Listing
September 2018
21 Reads

A Systematic Review of the Literature of the Three Related Disease Entities Cheilitis Granulomatosa, Orofacial Granulomatosis and Melkersson - Rosenthal Syndrome.

Curr Pediatr Rev 2018 ;14(3):196-203

Department of Pediatrics, Hospital Ostallgau-Kaufbeuren, Kaufbeuren, Germany.

Background And Objective: Melkersson Rosenthal syndrome (MRS) is a rare disorder of unknown etiology and comprises the triad: orofacial edema, recurrent facial paralysis and lingua plicata. In the current literature confusing heterogeneity exists, mixing together the historically grown terms cheilitis granulomatosa or granulomatous cheilitis, Melkersson Rosenthal syndrome and the umbrella term Orofacial Granulomatosis (OFG).

Methods: We provide a systematic review comprising all three disease entities of orofacial granulomatosis using the computerized database "Pubmed Medline" entering the keywords "orofacial granulomatosis" (141 references), "Melkersson-Rosenthal syndrome" (207 references), "granulomatous cheilitis" or "cheilitis granulomatosa" (102 references) back to 1956. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396314666180515113941DOI Listing
December 2018
2 Reads

Old and New Treatments for Pediatric Autoimmune Hepatitis.

Curr Pediatr Rev 2018 ;14(3):187-195

Pediatric Hepatology and Liver Transplantation, ISMETT UPMC Palermo, Palermo, Italy.

Background: Autoimmune hepatitis is a rare inflammatory disease of the liver that most frequently affects children and young adults. It is a multifactorial disease of unknown etiology, characteristically progressive in nature, and if left untreated, may lead to cirrhosis and terminal liver failure. It has been known for several decades now that immunosuppressive treatment convincingly alters the outcome of most patients with autoimmune hepatitis and as such it should be started as soon as diagnosis is made. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396314666180516130314DOI Listing
December 2018
3 Reads

Recent changes in the management of patients with food allergy in a tertiary referral centre: A Dietitian's perspective.

Curr Pediatr Rev 2018 May 14. Epub 2018 May 14.

Guys and St Thomas' NHS Foundation Trust. United Kingdom.

It is has been suggested that the prevalence of food allergy has increased over the last few decades with estimates now suggesting between 3.9-8% of children are food allergic (Kattan, 2016). Studies also suggest that rates of food allergy resolution are slowing, meaning more children are remaining allergic for longer (Sicherer et al, 2014). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396314666180514141131DOI Listing
May 2018
4 Reads

Advances in the Management of Food Allergy in Children.

Curr Pediatr Rev 2018 ;14(3):150-155

Childrens Allergy Service, University Hospitals of Leicester NHS Trust, Leicester, United Kingdom.

Food allergy is common in children. An accurate diagnosis remains a key element in order to instigate an effective management plan. Traditional management strategies have relied on a reactive approach, with allergen avoidance, management of accidental ingestion and monitoring for resolution. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396314666180508164224DOI Listing
December 2018
2 Reads

Febrile Neutropenia in Children with Cancer: Approach to Diagnosis and Treatment.

Curr Pediatr Rev 2018 ;14(3):204-209

Cerrahpasa Faculty of Medicine, Pediatric Hematology-Oncology, Istanbul University, Istanbul, Turkey.

Background: Febrile neutropenia is one of the major acute side effects of intensive treatment in pediatric cancer, necessitating prompt initiation of empirical broad-spectrum antibiotics. Patients may be classified as low or high risk according some risk factors (duration of neutropenia, depth of neutropenia, type of cancer, state of disease, bone marrow involvement, type of treatment, additional health problems). Initial evaluation of the febrile neutropenic child should include the history of the child, a detailed physical examination, blood culture (peripheral and catheter), urinalysis and culture, cultures of lesions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396314666180508121625DOI Listing
December 2018
1 Read

Anaphylaxis in Children: Epidemiology, Risk Factors and Management.

Curr Pediatr Rev 2018 ;14(3):180-186

Department of Pediatrics, Section of Immunology, Allergy and Rheumatology, Texas Children's Hospital, Feigin Center, 1102 Bates Avenue, Suite 330, MS: BCM320, Houston, Texas, 77030, United States.

Background: Anaphylaxis is defined as a serious, generalized or systemic allergic reaction that is rapid in onset and may cause death. It is unpredictable and can be the result of various allergic triggers including food, insect venom and medication. The European Anaphylaxis Registry confirmed food as the major elicitor of anaphylaxis in children, specifically hen's egg, cow's milk and nuts. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396314666180507115115DOI Listing
December 2018
4 Reads

Demystifying Dysbiosis: Can the Gut Microbiome Promote Oral Tolerance Over IgE-mediated Food Allergy?

Curr Pediatr Rev 2018 ;14(3):156-163

Department of Medicine, Section of Paediatrics, Imperial College London, St. Mary's Hospital Campus, Norfolk Place, United Kingdom.

The growing burden of food allergy is being driven by environmental exposures and the potential role of gut micro-organisms (or 'microbiota') is hotly debated. Early culture-based studies outlined that imbalances between commensal gut constituents ('dysbiosis') early in life may raise the risk of developing allergic disease. A number of studies using animal models describe mechanisms by which specific bacterial taxa within the gut microbiota, their diversity and dietary substrates such as fibre may promote oral tolerance. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396314666180507120424DOI Listing
December 2018
2 Reads

Mini Review - Asthma and Food Allergy.

Curr Pediatr Rev 2018 ;14(3):164-170

Division of Asthma, Allergy and Lung Biology, Department of Paediatric Allergy, King's College London and Guy's and St. Thomas' Hospitals NHS Foundation Trust, London, United Kingdom.

Background: It is well known that there is a common interplay between atopic conditions and that having one atopic condition can predispose to the development of others. The link between asthma and food allergy has been well researched over the years; although the exact interplay between the two atopic conditions is yet to be fully described. Research suggests that children who have both asthma and food allergy are at greater risk of more severe asthmatic episodes. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396314666180507121136DOI Listing
December 2018
3 Reads

Advances in Food Allergy Diagnosis.

Curr Pediatr Rev 2018 ;14(3):139-149

Children's Allergy Service, Evelina Children's Hospital, Guy's and St Thomas' Hospital, London, United Kingdom.

An accurate diagnosis of food allergy is extremely important to guide safe and yet not overly restrictive dietary management. The cornerstone of the diagnosis of food allergy is the clinical history; it allows appropriate selection of the allergens to be tested and interpretation of the results of allergy tests, namely Skin Prick Test (SPT), Specific IgE (sIgE) to allergen extracts and, more recently, specific IgE to allergen components and the Basophil Activation Test (BAT). SPT and sIgE to allergen extracts are very sensitive methods to detect IgE sensitization to a specific food and assess the possibility of spontaneous resolution. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396314666180423105842DOI Listing
December 2018
4 Reads

Special Traumatized Populations: Accidental Hypothermia in Children.

Curr Pediatr Rev 2018 ;14(1):28-33

Department of Pediatrics, Schulich School of Medicine, Western University, London, Ontario, ON, Canada.

Physicians caring for children in trauma settings must consider and treat hypothermia as a cause for morbidity and mortality. Knowledge of treatment of accidental hypothermia with and without an asphyxial event is paramount. Clinicians need to identify hypothermia immediately and be aware of the overall management utilizing aggressive rewarming and cardiopulmonary resuscitation to help improve the survival of these critically ill children. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396314666180412090930DOI Listing
September 2018
5 Reads

Ceftazidime/Avibactam and Ceftolozane/Tazobactam: Novel Therapy for Multidrug Resistant Gram Negative Infections in Children.

Curr Pediatr Rev 2018 ;14(2):97-109

Center for Anti-Infective Research and Development, Hartford Hospital, Hartford, CT 06102, United States.

The rise in Multidrug-resistant (MDR) infections has become a significant problem in both the developing countries and in the United States (U.S.). Read More

View Article

Download full-text PDF

Source
http://www.eurekaselect.com/160327/article
Publisher Site
http://dx.doi.org/10.2174/1573396314666180308150908DOI Listing
September 2018
10 Reads

The Prevalence of Dyslipidemia and Other Cardiovascular Risk Factors in Youth with Diabetes.

Curr Pediatr Rev 2017 ;13(4):277-280

Pediatric Endocrinology and Diabetes, Cook Children's Medical Center, Fort Worth, Texas, United States.

Background: Individuals diagnosed with diabetes mellitus have an increased risk of cardiovascular disease, often leading to premature morbidity and mortality. As the number of youth developing T1D and T2D continues to grow, early onset predisposes patients to a longer burden of disease and earlier onset of cardiovascular complications. Early identification and effective management and treatment of risk factors can lead to decreased cardiovascular events and improved quality of life. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396314666180221163924DOI Listing
April 2018
2 Reads

The Essential Role of Primary Caregiver in Early Detection of Familial Hypercholesterolemia and Cardiovascular Prevention.

Curr Pediatr Rev 2017 ;13(4):260-264

Department of Medicine, McGill University, Montreal, Quebec, Canada.

Familial hypercholesterolemia (FH) is a worldwide common autosomal inherited condition associated with premature cardiovascular diseases, both in men and in women (World frequency has been recently estimated to be as high as 1:250). Identifying FH cases early in life could represent a cornerstone to prevent fatal events in adult's life. Pediatricians are well positioned to evaluate the familial cardiovascular risk factors among their young patients, to make a diagnosis and to perform familial screening. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573396314666180221162556DOI Listing
April 2018
14 Reads

The Role of Point of Care Ultrasound in the Injured Paediatric Patient.

Curr Pediatr Rev 2018 ;14(1):41-47

Department of Pediatrics, Schulich School of Medicine, Western University, Ontario, ON, Canada.

The focus of this review is to examine the current state of paediatric Point of Care Ultrasound (POCUS) in the injured patient. POCUS has become useful across various medical specialties owing to its ease of use, reproducibility and non-ionizing qualities. Point of care ultrasound has advanced over the past years and has proven to be an extremely useful adjunct in the injured child. Read More

View Article

Download full-text PDF

Source
http://www.eurekaselect.com/159570/article
Publisher Site
http://dx.doi.org/10.2174/1573396314666180202102853DOI Listing
September 2018
7 Reads