744 results match your criteria Current Opinion in Supportive and Palliative Care[Journal]


Best practices on team communication: interprofessional practice in oncology.

Curr Opin Support Palliat Care 2019 Mar;13(1):69-74

Practice Based Research and Innovation, Sunnybrook Health Sciences Centre.

Purpose Of Review: Good communication is the cornerstone of interprofessional care teams providing optimized quality patient care. Over the last decade, advances in technology have provided tools to improve communication; however, opportunities still exist for innovation and implementation.

Recent Findings: The literature suggests that interprofessional education and assessment of team communication are fundamental in supporting collaborative care. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000412DOI Listing
March 2019
4 Reads

The role of splanchnic congestion and the intestinal microenvironment in the pathogenesis of advanced heart failure.

Curr Opin Support Palliat Care 2019 Mar;13(1):24-30

Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

Purpose Of Review: Right-sided heart failure, which is often present in the setting of advanced heart failure, is associated with cardiac cachexia, the cardiorenal syndrome, and adverse outcomes. Improved understanding of venous congestion of the splanchnic circulation, which may play a key role in the pathogenesis of right-sided heart failure, could lead to novel therapeutics to ameliorate heart failure. Here we provide an overview of right-sided heart failure, splanchnic hemodynamics, fluid homeostasis, and the intestinal microenvironment. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000414DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366455PMC
March 2019
1 Read

Communication in cancer: its impact on the experience of cancer care: communicating with the angry patient and the patient in denial.

Curr Opin Support Palliat Care 2019 Mar;13(1):46-52

Sacred Heart Health Service, St Vincent's Hospital, Sydney.

Purpose Of Review: This review aims to describe the recent literature on communication between cancer care clinicians and angry patients and patients in denial.

Recent Findings: Clinicians had improved perceived self-efficacy in responding to patient anger after completing anger management training, with a focus on reframing anger as a normative response to unmet needs. Psychosocial and mindfulness programmes for cancer patients were found to be useful for modifying anger response to stressors. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000410DOI Listing
March 2019
2 Reads

Cancer and fertility: optimizing communication between patients and healthcare providers.

Curr Opin Support Palliat Care 2019 Mar;13(1):53-58

Lady Davis Institute for Medical Research, Jewish General Hospital and McGill University, Montreal, Quebec, Canada.

Purpose Of Review: This article reviews the status of guidelines and recommendations for communication between patients with cancer and healthcare providers (HCPs) concerning fertility issues.

Recent Findings: The timing, the type of information provided, and the openness of HCPs can all affect how patients with cancer perceive discussions regarding fertility concerns and preservation. In addition, whether such discussions occur is associated with intrinsic factors, such as age and sex of the patients as well as HCP's knowledge level. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000413DOI Listing
March 2019
7 Reads

Editorial: Communication in cancer.

Curr Opin Support Palliat Care 2019 Mar;13(1):31-32

Department of Psychiatry, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/SPC.0000000000000416DOI Listing
March 2019
1 Read

Editorial: Culture, treatment paradigms, and advanced heart failure.

Authors:
James M Beattie

Curr Opin Support Palliat Care 2019 Mar;13(1):1-2

Cicely Saunders Institute, King's College London, London, UK.

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http://dx.doi.org/10.1097/SPC.0000000000000415DOI Listing
March 2019
2 Reads

Oncologists communicating with patients about assisted dying.

Curr Opin Support Palliat Care 2019 Mar;13(1):59-63

Sunnybrook Health Sciences Centre.

Purpose Of Review: Across all jurisdictions in which assisted dying is legally permissible, cancer is the primary reported underlying diagnosis. Therefore, oncologists are likely to be asked about assisted dying and should be equipped to respond to inquiries or requests for assisted dying. Because Medical Assistance in Dying was legalized in Canada in 2016, it is a relatively new end-of-life practice and has prompted the need to revisit the academic literature to inform communication with patients about assisted dying. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000411DOI Listing
March 2019
1 Read

Communication involving special populations: older adults with cancer.

Curr Opin Support Palliat Care 2019 Mar;13(1):64-68

Division of Geriatrics and Palliative Medicine, Weill Medical College of Cornell University, New York.

Purpose Of Review: Cancer has a high incidence and death rate among older adults. The objective of this article is to summarize current literature about communication between older adults and medical professionals in cancer care. Our article addresses four categories related to communication: first, ageism; second, screening; third, treatment; and fourth, end of life (EoL) care. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000408DOI Listing
March 2019
1 Read

Communication skills training for healthcare professionals in oncology over the past decade: a systematic review of reviews.

Curr Opin Support Palliat Care 2019 Mar;13(1):33-45

Amsterdam UMC, University of Amsterdam, Medical Psychology.

Purpose Of Review: Effective communication in cancer care requires complex communication skills of healthcare professionals (HCPs), which can be advanced by communication skills training (CST). The number of empirical studies on CST has grown steadily over the last decade. However, controversies on CST abound. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000409DOI Listing
March 2019
2 Reads

Can a complex adaptive systems perspective support the resiliency of the heart failure patient - informal caregiver dyad?

Curr Opin Support Palliat Care 2019 Mar;13(1):9-13

Centre for Health Education Scholarship, Department of Family Practice, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia.

Purpose Of Review: A holistic palliative approach for heart failure care emphasizes supporting nonprofessional informal caregivers. Informal caregivers play a vital role caring for heart failure patients. However, caregiving negatively affects informal caregivers' well being, and in turn heart failure patients' health outcomes. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000406DOI Listing
March 2019
3 Reads

Structural heart disease: one valve does not fit all.

Curr Opin Support Palliat Care 2019 Mar;13(1):14-17

University Hospitals Cleveland Medical Center/Harrington Heart & Vascular Institute, Cleveland, Ohio, USA.

Purpose Of Review: Highlight the difficulties patients, physicians, and the global economy face in relation to treatment of structural heart diseases. It is easy to be carried away by the excitement of medical advancement; however, it is difficult to demonstrate restraint. Transcatheter aortic valve replacement (TAVR) is a modern marvel that can help many patients when utilized appropriately. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000407DOI Listing
March 2019
17 Reads

The lived experience of breathlessness for people diagnosed with heart failure: a qualitative synthesis of the literature.

Curr Opin Support Palliat Care 2019 Mar;13(1):18-23

College of Nursing, East Carolina University, Greenville, North Carolina, USA.

Purpose Of Review: The experience of breathlessness in patients with heart failure is understudied. This review was aimed at evaluating the most recent qualitative findings regarding the experience of breathlessness in persons diagnosed with heart failure.

Recent Findings: A literature search was conducted using Pubmed, Psycinfo, BNI, Cinahl and Google Scholar including studies on breathlessness experience in patients with heart failure, published between 2017 and 2018. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000405DOI Listing
March 2019
1 Read

Māori: living and dying with cardiovascular disease in Aotearoa New Zealand.

Curr Opin Support Palliat Care 2019 Mar;13(1):3-8

School of Nursing, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.

Purpose Of Review: This article provides an informed perspective on cardiovascular disease (CVD) and palliative care need among Māori New Zealanders. High Māori CVD risk factors will contribute to a sharp increase in older Māori deaths which has implications for health and palliative care service provision.

Recent Findings: CVD is New Zealand's leading cause of premature deaths and disability among Māori. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000404DOI Listing
March 2019
8 Reads

Nutrition support for treating cancer-associated weight loss: an update.

Curr Opin Support Palliat Care 2018 Dec;12(4):434-438

Department of Clinical Medicine, Sapienza University of Rome, Italy.

Purpose Of Review: Patients with cancer present high risk for involuntary body weight loss and reduced food intake, which, contributing to progressive tissue wasting and affecting the nutritional status, are often under-estimated in the clinical practice. In this article, we aimed at focusing on cancer-associated weight loss and investigating recent evidences on the indications of nutritional interventions to treat this condition.

Recent Findings: During the last few years, increased emphasis has been addressed on the mechanisms underlying body weight loss in cancer that can be induced by either cancer metabolism and inflammation, either several side-effects of the anticancer treatments. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000383DOI Listing
December 2018
7 Reads

Targeting the divergent TGFβ superfamily cytokine MIC-1/GDF15 for therapy of anorexia/cachexia syndromes.

Curr Opin Support Palliat Care 2018 Dec;12(4):404-409

St Vincent's Centre for Applied Medical Research, St Vincent's Hospital and University of New South Wales, Sydney, NSW, Australia.

Purpose Of Review: To review recent finding on MIC-1/GDF15 and re-evaluate it as a potential target for the therapy of anorexia/cachexia syndromes.

Recent Findings: MIC-1/GDF15 consistently induces anorexia/cachexia in animal models. Its actions on brainstem feeding centers leads to anorexia, inducing prolonged undernutrition and consequent loss of both lean and fat mass. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000384DOI Listing
December 2018
3 Reads

Hemato-oncology and palliative care teams: is it time for an integrated approach to patient care?

Curr Opin Support Palliat Care 2018 Dec;12(4):530-537

Massachusetts General Hospital, Boston, Massachusetts, USA.

Purpose Of Review: Integrated palliative care for those with advanced solid tumors yields significant benefits in patient and caregiver outcomes. However, most palliative care clinical trials have excluded patients with hematologic malignancies. There is growing interest in whether integrated palliative care may yield similar benefits in hematologic malignancy patients and caregivers, but there has been little direct evidence of benefit in this population. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000385DOI Listing
December 2018
1 Read

Instruments to evaluate complexity in end-of-life care.

Curr Opin Support Palliat Care 2018 Dec;12(4):480-488

Palliative Care Department, University of Munich, Munich, Germany.

Purpose Of Review: The growing number of patients with terminal and chronic conditions and co-morbidities constitutes a challenge for any healthcare system, to provide effective and efficient patient-centred care at the end of life. Resources are limited, and complexity is rising within patients' situations and healthcare professionals interventions. This review presents the state of art of the role of complexity in specialist palliative care provision. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000403DOI Listing
December 2018
16 Reads

'The shoulders, clavicles, chest and thighs melt away': a compilation of reviews on cachexia.

Curr Opin Support Palliat Care 2018 Dec;12(4):393

Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1097/SPC.0000000000000399DOI Listing
December 2018
4 Reads

Targeting IL-1α in cancer cachexia: a narrative review.

Curr Opin Support Palliat Care 2018 Dec;12(4):453-459

Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh.

Purpose Of Review: Cachexia is defined as ongoing loss of skeletal muscle mass, with or without depletion of adipose tissue and is a common syndrome in cancer patients, affecting 50% of those diagnosed. Cachexia, which cannot be fully reversed and causes significant functional impairment is caused by various mechanisms such as an altered energy balance and disruption of homeostatic control by the central nervous system. This central nervous system deregulation involves hypothalamic pituitary adrenal (HPA) axis stimulation, which can be triggered by IL-1R1 engagement on neuronal processes and endothelium in the microvasculature of the hypothalamus. Read More

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http://Insights.ovid.com/crossref?an=01263393-900000000-9942
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http://dx.doi.org/10.1097/SPC.0000000000000398DOI Listing
December 2018
2 Reads

The role of day care in supporting older people living with long-term conditions.

Curr Opin Support Palliat Care 2018 Dec;12(4):510-515

Academic Palliative and Supportive Care Studies Group (APSCSG), University of Liverpool, Brownlow Hill, Liverpool, England.

Purpose Of Review: For older people with long-term conditions, regular structured activities within a community setting meeting others are thought to improve well being and quality of life. Historically local authority-run day care centres were widely available, but austerity measures have meant that in many areas, such provision has been markedly reduced and different models of day care services are being developed. There is little known about outcomes of day care provision for older people with long-term conditions. Read More

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http://Insights.ovid.com/crossref?an=01263393-900000000-9942
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http://dx.doi.org/10.1097/SPC.0000000000000391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221434PMC
December 2018
2 Reads

Palliative care teaching shapes medical undergraduate students' professional development: a scoping review.

Curr Opin Support Palliat Care 2018 Dec;12(4):495-503

ATLANTES Research Programme, Institute for Culture and Society (ICS), University of Navarra.

Purpose Of Review: The aim of this review is to understand how palliative care teaching (PCT) as a patient-centered learning model, influences medical undergraduate students' professional development.

Recent Findings: To study PCT medical undergraduate students' learning experiences, we have employed the medical teaching concept, 'hidden curriculum,' as a way of describing attitudes and behavior conveyed implicitly by palliative care educators. Fifteen studies were selected: ten of those studies used a qualitative approach; two are theoretical explanations of the topic explored, one guideline, one review and just one quantitative study, made up the review. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000402DOI Listing
December 2018
2 Reads

Compassion in palliative care: a review.

Curr Opin Support Palliat Care 2018 Dec;12(4):472-479

New Health Foundation, Sevilla, Spain.

Purpose Of Review: Compassion has been recognized as a key aspect of high-quality healthcare, particularly in palliative care. This article provides a general review of the current understanding of compassion in palliative care and summarizes emergent compassionate initiatives in palliative care at three interdependent levels: compassion for patients, compassion in healthcare professionals, and compassionate communities at the end of life.

Recent Findings: Compassion is a constructive response to suffering that enhances treatment outcomes, fosters the dignity of the recipient, and provides self-care for the giver. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000393DOI Listing
December 2018
3 Reads

Technology for improving accessibility of end-of-life care: Extension for Community Healthcare Outcomes Project.

Curr Opin Support Palliat Care 2018 Dec;12(4):466-471

Hospital Maciel Palliative Care Service - Medical School, Universidad de la República, Montevideo, Uruguay.

Purpose Of Review: To describe how Project ECHO works and to analyze what has been published on Project ECHO Palliative Care (Project ECHO PC) over the last 18 months.

Recent Findings: Only two articles on Project ECHO PC have been published over the last 18 months: a descriptive study of experiences in seven health centers of the United States, the United Kingdom, Uruguay and India; and a quantitative and qualitative study of the impact of the teleECHO clinic on physicians and nurses in Northern Ireland, which reports a significant boost in knowledge acquisition and self-efficacy.

Summary: Project ECHO is an innovative telemedicine strategy, which creates learning communities, which use a standardized methodology and benefits healthcare professionals, particularly primary care providers or practitioners based on remote or rural areas. Read More

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http://Insights.ovid.com/crossref?an=01263393-900000000-9941
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http://dx.doi.org/10.1097/SPC.0000000000000390DOI Listing
December 2018
2 Reads

Predictors of reliably high-value end-of-life care.

Curr Opin Support Palliat Care 2018 Dec;12(4):460-465

Brookdale Department of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai.

Purpose Of Review: Care near the end of life is expensive and frequently not aligned with the expressed preferences of decedents, creating an opportunity to improve value, or increase quality while lowering cost. This review examines publications from 2017 and 2018 on interventions and policies associated with high-value end-of-life care. Innovations in video and web-based advance care planning are promising to improve preference-congruent care at low cost. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000392DOI Listing
December 2018
2 Reads

Managing anaemia in bone marrow failure syndromes.

Curr Opin Support Palliat Care 2018 Dec;12(4):538-541

Department of Haematology, University Hospital Southampton NHSFT, Shirley, Southampton, England.

Purpose Of Review: Anaemia is a common haematological presentation in patients with bone marrow failure, yet a challenging condition to treat. As anaemia has a direct impact on the patient's symptoms, managing anaemia in the common bone marrow failure conditions, such as myelodysplastic syndrome will help to improve the quality of life. This review discusses the available treatment options and the benefit of improving the haemoglobin level. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000397DOI Listing
December 2018
7 Reads

Endpoints in clinical trials in cancer cachexia: where to start?

Curr Opin Support Palliat Care 2018 Dec;12(4):445-452

European Palliative Care Research Centre (PRC), Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, NTNU - Norwegian University of Science and Technology.

Purpose Of Review: The lack of agreement and knowledge of optimal endpoints in cachexia trials have impeded progress in finding interventions counteracting the devastating effects cancer cachexia has on morbidity and mortality. An endpoint should both be sensitive enough to detect change and specific enough not to be influenced by other conditions or treatments.

Recent Findings: There is a wealth of potential and applied endpoints in trials investigating cachexia. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000387DOI Listing
December 2018
2 Reads

Psychological burden of haematological cancer on patient and family: is it time for a multisystem approach?

Curr Opin Support Palliat Care 2018 Dec;12(4):518-521

Hospital Palliative Care Team, University Hospital Southampton, Southampton, UK.

Purpose Of Review: Literature addressing the psychological impact of haematological cancers on patients and their families is sparse. New evidence might prompt a change in approach to the assessment and management of psychological burden.

Recent Findings: The diagnosis, treatment and surveillance of haematological cancers often have a profound psychological impact on patients and their families and can result in clinically significant problems and increased carer stress. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000396DOI Listing
December 2018
13 Reads

We all need support but can our patients help us to help them?

Curr Opin Support Palliat Care 2018 Dec;12(4):516-517

Department of Haematology, University Hospital Southampton (NHS Foundation Trust), Southampton General Hospital, Southampton, UK.

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http://dx.doi.org/10.1097/SPC.0000000000000389DOI Listing
December 2018
2 Reads

How should we assess patient-reported outcomes in the onco-hematology clinic?

Curr Opin Support Palliat Care 2018 Dec;12(4):522-529

Innsbruck Institute of Patient-centered Outcome Research (IIPCOR), Innsbruck, Austria.

Purpose Of Review: The improvement of clinical outcomes in hematologic malignancies has paved the way for a more systematic patient-reported outcomes (PROs) assessment in routine clinical practice. PROs help to narrow the gap between patients' and healthcare professionals' view of patient health and treatment success. This review outlines key aspects of planning and performing PRO assessments in daily routine such as the selection of PRO instruments, electronic PRO data collection, and the presentation and interpretation of PRO results. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000386DOI Listing
December 2018
1 Read

Palliative care for all? How can Brazil develop a palliative care service founded on principles of equity and access for all?

Curr Opin Support Palliat Care 2018 Dec;12(4):504-509

Compassionate Communities.

Purpose Of Review: Despite the historical international development of palliative care over the last 50 years, provision of equity of care and access to appropriate medication remains a major problem in many countries across the world. Interest in the public health approach to end-of-life care has grown over the last 20 years. Models of palliative care, which are affordable and provide equity of care are changing through these new concepts. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000394DOI Listing
December 2018
11 Reads

What's next in using CT scans to better understand cachexia?

Curr Opin Support Palliat Care 2018 Dec;12(4):427-433

Biostatistics and Epidemiology Unit, Gustave Roussy Cancer Campus.

Purpose Of Review: Cachexia (CAX), a protein metabolism disorder commonly associated with cancer, can be evaluated by computed tomography (CT) scan assessment of skeletal muscle mass (SMM), a parameter associated with patient outcome. This review analyzes current barriers for using CT scans of SMM in routine management for defining prognostic risk groups, and proposes new areas of research to reach a better understanding of CAX mechanisms.

Recent Findings: Current research is focused on establishing a robust and relevant CAX staging system to reach a consensual definition. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000388DOI Listing
December 2018
19 Reads

Benzodiazepines for agitation in patients with delirium: selecting the right patient, right time, and right indication.

Authors:
David Hui

Curr Opin Support Palliat Care 2018 Dec;12(4):489-494

Department of Palliative Care, Rehabilitation and Integrative Medicine, MD Anderson Cancer Center, Houston, USA.

Purpose Of Review: To provide an evidence-based synopsis on the role of benzodiazepines in patients with agitated delirium.

Recent Findings: Existing evidence supports the use of benzodiazepines in two specific delirium settings: persistent agitation in patients with terminal delirium and delirium tremens. In the setting of terminal delirium, the goal of care is to maximize comfort, recognizing that patients are unlikely to recover from their delirium. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000395DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261485PMC
December 2018
3 Reads

The relationship between muscle mass and function in cancer cachexia: smoke and mirrors?

Curr Opin Support Palliat Care 2018 Dec;12(4):439-444

Clinical Surgery, University of Edinburgh, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom.

Purpose Of Review: Randomized clinical trials of cancer cachexia interventions are based on the premise that an increase in the muscle mass of patients is associated with consequent improvements in muscle function, and ultimately, quality of life. However, recent trials that have succeeded in demonstrating increases in lean body mass have been unable to show associated increases in patient physical function. In this review, we examine the potential causes for this lack of association between muscle mass and function in cancer cachexia, paying particular attention to those factors that may be at play when using body composition analysis techniques involving cross-sectional imaging. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000381DOI Listing
December 2018
1 Read

How much does reduced food intake contribute to cancer-associated weight loss?

Curr Opin Support Palliat Care 2018 Dec;12(4):410-419

Department of Oncology, University of Alberta, Edmonton, Alberta, Canada.

Purpose Of Review: An international consensus group defined cancer cachexia as a syndrome of involuntary weight loss, characterized by loss of skeletal muscle (with or without fat loss), which is driven by a variable combination of reduced food intake and altered metabolism.This review presents recent studies that evaluated the contribution of reduced food intake to cancer-associated weight loss.

Recent Findings: Four studies examined food intake in relation to weight loss. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000379DOI Listing
December 2018
1 Read

Preservation of muscle mass as a strategy to reduce the toxic effects of cancer chemotherapy on body composition.

Curr Opin Support Palliat Care 2018 Dec;12(4):420-426

Department of Anatomy and Cell Biology.

Purpose Of Review: Cancer patients undergoing chemotherapy often experience very debilitating side effects, including unintentional weight loss, nausea, and vomiting. Changes in body composition, specifically lean body mass (LBM), are known to have important implications for anticancer drug toxicity and cancer prognosis. Currently, chemotherapy dosing is based on calculation of body surface area, although this approximation does not take into consideration the variability in lean and adipose tissue mass. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221433PMC
December 2018
14 Reads

Understanding sex differences in the regulation of cancer-induced muscle wasting.

Curr Opin Support Palliat Care 2018 Dec;12(4):394-403

Department of Exercise Science, University of South Carolina, Public Health Research Center, Columbia, USA.

Purpose Of Review: We highlight evidence for sexual dimorphism in preclinical and clinical studies investigating the cause and treatment of cancer cachexia.

Recent Findings: Cancer cachexia is unintended bodyweight loss occurring with cancer, and skeletal muscle wasting is a critical predictor of negative outcomes in the cancer patient. Skeletal muscle exhibits sexual dimorphism in fiber type, function, and regeneration capacity. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000380DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239206PMC
December 2018
3 Reads

Improving outcome in patients with prostate and kidney cancer: heading in the right direction?

Authors:
Fred Saad

Curr Opin Support Palliat Care 2018 Sep;12(3):323-324

Centre Hospitalier de l'Université de Montreal, Montreal Cancer Institute/CRCHUM, Montreal, Canada.

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http://dx.doi.org/10.1097/SPC.0000000000000368DOI Listing
September 2018
2 Reads

Psychological support for patients with cancer: evidence review and suggestions for future directions.

Curr Opin Support Palliat Care 2018 Sep;12(3):276-292

Centre for Medical Psychology & Evidence-based Decision Making, School of Psychology, University of Sydney, Sydney, New South Wales, Australia.

Purpose Of Review: Psychological distress and mental health comorbidity are common in cancer. Various therapeutic frameworks have been used for interventions to improve psychological wellbeing and quality of life in cancer patients with mixed results. This article reviews contributions to that literature published since January 2017. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000360DOI Listing
September 2018
9 Reads

The role of primary care in supporting patients living with and beyond cancer.

Curr Opin Support Palliat Care 2018 Sep;12(3):261-267

School of Nursing and Midwifery, Faculty Health and Life Sciences, University of Oxford, Oxford, UK.

Purpose Of Review: The prevalence of cancer survivors is increasing. Those living with and beyond a cancer diagnosis have a range of physical, psychosocial and practical needs. This review aims to discuss the role of primary care in meeting these needs. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000369DOI Listing
September 2018
17 Reads

Pathophysiological mechanisms of exertional breathlessness in chronic obstructive pulmonary disease and interstitial lung disease.

Curr Opin Support Palliat Care 2018 Sep;12(3):237-245

Department of Physical Therapy, University of British Columbia.

Purpose Of Review: Breathlessness is a common and distressing symptom in patients with chronic obstructive pulmonary disease (COPD) and fibrotic interstitial lung disease (ILD), particularly during exercise. Effective medical management of exertional breathlessness in people living with COPD and fibrotic ILD is challenging for healthcare providers and requires an understanding of its mechanisms. Thus, in this brief review we summarize recent advances in our understanding of the pathophysiological mechanisms of exertional breathlessness in COPD and fibrotic ILD. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000377DOI Listing
September 2018
15 Reads

Learning 30 years behind….

Curr Opin Support Palliat Care 2018 Sep;12(3):211-213

Wolfson Palliative Care Research Centre, University of Hull, Hull.

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http://dx.doi.org/10.1097/SPC.0000000000000366DOI Listing
September 2018
3 Reads

Exercise and movement in musculoskeletal pain: a double-edged problem.

Curr Opin Support Palliat Care 2018 Sep;12(3):388-392

Faccanoni Hospital, Habilita Hospitals & Research, Sarnico, Bergamo, Italy.

Purpose Of Review: Exercise and movement are increasingly used in pain management and in palliative care, outside the traditional context of physical medicine and rehabilitation. This critical review aims to provide specialists in pain and palliative medicine with recent insights into the use of exercise and movement in the approach to musculoskeletal disorders when pain and disability are the major complaints.

Recent Findings: If there is a common sense linking pain and movement in both directions, that is pain influencing movement - as a withdrawal movement or a reduction of mobility as a defense reaction - or movement evoking pain, not so clear and recognized is the link between exercise and movement in controlling pain. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000365DOI Listing
September 2018
2 Reads

Breathlessness in the emergency care setting.

Curr Opin Support Palliat Care 2018 Sep;12(3):232-236

Wolfson Palliative Care Research Centre, Hull York Medical School, University of Hull, Hull, UK.

Purpose Of Review: Breathlessness is one of the most common reasons for presentation at the emergency department (ED). The present review summarizes work published from 2017, which focuses on the symptom of breathlessness in its own right rather than as a signpost to diagnosis in relation to presentation to the ED.

Recent Findings: Seven relevant papers are included in the present review. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000374DOI Listing
September 2018
3 Reads

Role of immunotherapy in kidney cancer.

Curr Opin Support Palliat Care 2018 Sep;12(3):325-333

Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Québec, Canada.

Purpose Of Review: To summarize current knowledge on promising immunotherapeutic agents and to provide a brief outline of current use of immunotherapeutic agents in patients with locally advanced or metastatic renal cell carcinoma (RCC).

Recent Findings: Immunotherapy with mAbs directed against programed death cell protein 1, programed death-ligand 1 (PD-L1) and cytotoxic T-Lymphocyte Antigen 4 has become new first-line standard of care for moderate and poor-risk metastatic RCC patients. Similarly, the combination immune-oncology treatment and vascular endothelial growth factor (VEGF) mAbs also showed promising results in first-line therapy despite relative data immaturity. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000363DOI Listing
September 2018
1 Read

Supporting self-management in palliative care throughout the cancer care trajectory.

Curr Opin Support Palliat Care 2018 Sep;12(3):299-307

Yale School of Nursing, West Haven, Connecticut.

Purpose Of Review: Despite increased survivorship and the subsequent need for chronic management of cancer, the association of self-management and palliative care is still emerging within cancer care. Routine and timely use of self-management strategies in the palliative setting can help reduce self-management burden and maximize quality of life. In this review, we consider the complementary relationship of self-management and palliative care and how they support living with cancer as a chronic illness. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000373DOI Listing
September 2018
2 Reads

Myofascial pain: so common, and yet not understood.

Authors:
Roberto Casale

Curr Opin Support Palliat Care 2018 Sep;12(3):372

Habilita, Hospitals & Research, Department of Advanced Technology Rehabilitation & Pain Rehabilitation Units, Zingonia di Ciserano (Bg), Italy.

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http://dx.doi.org/10.1097/SPC.0000000000000367DOI Listing
September 2018
4 Reads

Treatment of hormone-naïve metastatic prostate cancer.

Curr Opin Support Palliat Care 2018 Sep;12(3):334-338

Département De Médecine Oncologique, Institut Gustave Roussy, Université Paris-Saclay, Paris, France.

Purpose Of Review: Until 2015, androgen deprivation therapy (ADT) alone was the standard-of-care for metastatic hormone-naïve prostate cancer (mHNPC). In the last decade, important landmark therapeutic advances occurred in the management of these patients permitting improvement of their survival.

Recent Findings: At least two prospective randomized trials proved upfront docetaxel (DOC) + ADT benefit consequently providing strong evidence for guidelines modifications. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000359DOI Listing
September 2018
2 Reads

Management of nonmetastatic castration-resistant prostate cancer.

Curr Opin Support Palliat Care 2018 Sep;12(3):366-371

Centre Hospitalier de l'Université de Montréal (CHUM), Montreal, Quebec, Canada.

Purpose Of Review: The widespread use of prostate-specific antigen (PSA) resulted in stage migration of prostate cancer where androgen deprivation therapy (ADT) is administered for biochemical recurrence in patients following primary treatment. A proportion of these patients progress to a disease state termed nonmetastatic castration-resistant prostate cancer (nmCRPC), with a rising PSA despite ADT and without evidence of metastases on conventional imaging. We will review the treatment options in nmCRPC, especially in light of recent trials showing significant improvement in metastasis-free survival with newer agents. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000356DOI Listing
September 2018
2 Reads

A contemporary review about the management of radiation-induced hemorrhagic cystitis.

Curr Opin Support Palliat Care 2018 Sep;12(3):344-350

Department of Radiation Oncology.

Purpose Of Review: There are various specific therapeutic intervention available to treat hemorrhagic cystitis, once emergency treatment has been carried out. The lack of prospective studies, because of the relative rarity of this condition, makes it difficult to hierarchize the therapeutic sequence. The present review presents and summarizes the literature published on radiation-induced hemorrhagic cystitis from April 2015, date of a precedent exhaustive review, to March 2018. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000375DOI Listing
September 2018
3 Reads

Local ablative stereotactic body radiotherapy for oligometastatic prostate cancer.

Curr Opin Support Palliat Care 2018 Sep;12(3):351-358

Department of Medical Physics, Jewish General Hospital, McGill University, Montreal, Quebec, Canada.

Purpose Of Review: The oligometastases is considered an intermediate state of the disease between localized and wide spread metastases. Local ablative therapy to oligometastatic prostate cancer is gaining significant traction and stereotactic body radiotherapy (SBRT) is an emerging treatment modality for this patient population. In this review, we report our literature review of SBRT to prostate oligometastases. Read More

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http://dx.doi.org/10.1097/SPC.0000000000000371DOI Listing
September 2018
21 Reads