481 results match your criteria Current Cardiology Reviews [Journal]


Atrial and brain natriuretic peptides- benefits and limits of their use in cardiovascular diseases.

Curr Cardiol Rev 2019 Mar 26. Epub 2019 Mar 26.

Department of Internal Medicine- Cardiology, Craiova University of Medicine and Pharmacy, Craiova 200349. Romania.

Natriuretic peptides, produced by cardiac myocytes, are regulators of the intravascular volume and blood pressure, also having neuroendocrine, metabolic and growth controlling effects. In heart failure, their synthesis increases exponentially as part of the neuroendocrine activation, but their beneficial effects are diminished. The paper reviews relevant data about their role as diagnosis and prognosis markers in heart failure, the hemodynamic and clinical benefits of their use as therapy in heart failure, together with the main adverse effects, information useful in daily clinical practice. Read More

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http://dx.doi.org/10.2174/1573403X15666190326150550DOI Listing
March 2019
6 Reads

Gender differences in hemodynamic regulation and cardiovascular adaptations to dynamic exercise.

Curr Cardiol Rev 2019 Mar 21. Epub 2019 Mar 21.

Department of Medical Sciences and Public Health, Sports Physiology Lab., University of Cagliari, Cagliari. Italy.

Exercise is a major challenge for cardiovascular apparatus since it recruits chronotropic, inotropic, pre-load, and afterload reserves. Regular physical training induces several physiological adaptations leading to an increase in both cardiac volume and mass. It appears that several gender-related physiological and morphological differences exist in the cardiovascular adjustments and adaptations to dynamic exercise in humans. Read More

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http://dx.doi.org/10.2174/1573403X15666190321141856DOI Listing
March 2019
1 Read

Physiological and Pathological Role of TRPV1, TRPV2 and TRPV4 Channels in Heart.

Curr Cardiol Rev 2019 Mar 6. Epub 2019 Mar 6.

Department of Pathology, University of Kentucky College of Medicine, Lexington, KY. United States.

Transient receptor potential vanilloid channel 2 (TRPV2) is required for normal cardiac contractility. The stimulation of TRPV1 in isolated cardiomyocytes can aggravate the effect of hypoxia/reoxygenation (H/R) on H9C2 cells. The knockout of the TRPV1 gene promotes increased tolerance of the isolated perfused heart to the impact of ischemia/reperfusion (I/R). Read More

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http://dx.doi.org/10.2174/1573403X15666190307112326DOI Listing
March 2019
5 Reads

Hyponatremia in Heart Failure: Pathogenesis and Management.

Curr Cardiol Rev 2019 Mar 5. Epub 2019 Mar 5.

Department of Internal Medicine, Icahn School of Medicine at Mount Sinai St' Luke and Mount Sinai West, New York, NY. United States.

Hyponatremia is a very common electrolyte abnormality, associated with poor short- and long-term outcomes in patients with heart failure (HF). Two opposite processes can result in hyponatremia in this setting: volume overload with dilutional hypervolemic hyponatremia from congestion, and hypovolemic hyponatremia from excessive use of natriuretics. These two conditions require different therapeutic approaches. Read More

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http://dx.doi.org/10.2174/1573403X15666190306111812DOI Listing
March 2019
10 Reads

[Risk-stratification strategy for sudden cardiac death in the very young children with asymptomatic ventricular preexcitation].

Curr Cardiol Rev 2019 Mar 1. Epub 2019 Mar 1.

Pediatric Cardiology department of Puerta del Mar Universitary Hospital. Cadiz. Spain.

Asymptomatic VPE refers to the presence of this abnormal ECG pattern in the absence of any symptoms. The natural history in these patients is usually benign, and most children (60%) with VPE are usually asymptomatic. However, sudden cardiac death (SCD) has been reported to be the initial symptom in many patients too. Read More

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http://dx.doi.org/10.2174/1573403X15666190301150754DOI Listing
March 2019
1 Read

Trigger, Signaling Mechanism and End Effector of Cardioprotective Effect of Remote Postconditioning of Heart.

Curr Cardiol Rev 2019 Feb 25. Epub 2019 Feb 25.

Department of Pathology, University of Kentucky College of Medicine, Lexington, KY. United States.

The hypothetical trigger of remote postconditioning (RPost) of the heart is the high-molecular weight hydrophobic peptide(s). Nitric oxide and adenosine serve as intermediaries between the peptide and intracellular structures. The role of the autonomic nervous system in RPost requires further study. Read More

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http://dx.doi.org/10.2174/1573403X15666190226095820DOI Listing
February 2019
1 Read

Low-Dose Radiation Advances in Coronary Computed Tomography Angiography in the Diagnosis of Coronary Artery Disease.

Curr Cardiol Rev 2019 Feb 22. Epub 2019 Feb 22.

Morriston Hospital, Heol Maes Eglwys, Morriston, Swansea, SA6 6NL. United Kingdom.

Background: Coronary computed tomography angiography (CCTA) is now widely used in the diagnosis of coronary artery disease since it is a rapid, minimally invasive test with a diagnostic accuracy comparable to coronary angiography. However, to meet demands for increasing spatial and temporal resolution, higher x-ray radiation doses are required to circumvent the resulting increase in image noise. Exposure to high doses of ionizing radiation with CT imaging is a major health concern due to the potential risk of radiation-associated malignancy. Read More

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http://dx.doi.org/10.2174/1573403X15666190222163737DOI Listing
February 2019

Hematological parameters as prognostic biomarkers in patients with cardiovascular diseases.

Curr Cardiol Rev 2019 Feb 25. Epub 2019 Feb 25.

University of Pernambuco, Recife, Pernambuco. Brazil.

Cardiovascular diseases are the major causes of preventable health loss from disease in the world and leads to functional disturbances including hematological parameters. The inflammatory and hypoxemic nature in cardiovascular diseases causes a stimulus in the bone marrow and, depending on the intensity of this stimulus, there are a release of immature cells or increase of other cells in the bloodstream. Therefore, their presence in the circulation are important variables used to diagnose, stratify and predict diseases. Read More

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http://dx.doi.org/10.2174/1573403X15666190225123544DOI Listing
February 2019
1 Read

Implantable Cardioverter-Defibrillators in Patients with ESRD: Complications, Management, and Literature Review.

Curr Cardiol Rev 2019 Jan 18. Epub 2019 Jan 18.

Cardiac Primary Prevention Research Center(CPPRC),Department of Electrophysiology, Tehran Heart Center, Tehran University of Medical Sciences, Tehran. Iran.

Purpose: Cardiovascular diseases are the leading cause of death among dialysis patients, accounting for about 40% of all their mortalities. Sudden cardiac death (SCD) is culpable for 37.5% of all deaths among patients with end-stage renal disease (ESRD). Read More

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http://dx.doi.org/10.2174/1573403X15666190118123754DOI Listing
January 2019
5 Reads

Multimodalities Imaging of Immunoglobulin 4-related Cardiovascular Disorders.

Authors:
Ahmed Fathala

Curr Cardiol Rev 2019 Jan 16. Epub 2019 Jan 16.

Department of Radiology, King Fasial Hospital. Saudi Arabia.

Immunoglobulin 4 (IgG4)-related systemic disease (IgG4-RSD) is a systemic inflammatory disease characterized by elevation of serum IgG4. IgG4-RSD can affect any organ in the body, and the list of organs associated with this condition is growing steadily. IgG4-related cardiovascular disease affects the coronary arteries, heart valves, myocardium, pericardium, aorta, pulmonary and peripheral vessels. Read More

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http://dx.doi.org/10.2174/1573403X15666190117101607DOI Listing
January 2019
13 Reads

Emergence of three dimensional printed cardiac tissue: Opportunities and challenges in cardiovascular diseases.

Curr Cardiol Rev 2019 01 12. Epub 2019 Jan 12.

School of Pharmacy and Pharmaceutical Sciences, Ulster University, Coleraine, County Londonderry, BT52 1SA, Northern Ireland, United Kingdom

Three-dimensional (3D) printing, also known as additive manufacturing, was developed originally for engineering applications. Since its early advancements, there has been a relentless development in enthusiasm for this innovation in biomedical research. It allows for the fabrication of structures with both complex geometries and heterogeneous material properties. Read More

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http://dx.doi.org/10.2174/1573403X15666190112154710DOI Listing
January 2019
3 Reads

Clinical significance of ductus venosus waveform as generated by pressure-volume changes in the fetal heart.

Curr Cardiol Rev 2019 Jan 15. Epub 2019 Jan 15.

Instituto de Ciências Biomédicas Abel Salazar, University of Porto, Porto. Portugal.

The ductus venosus is a vascular shunt situated within the fetal liver parenchyma connecting the umbilical vein to the inferior vena cava. This vessel acts as a bypass of the liver microcirculation and plays a critical role in the fetal circulation. The ductus venosus allows oxygenated and nutrient-rich venous blood to flow from the placenta to the myocardium and brain. Read More

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http://dx.doi.org/10.2174/1573403X15666190115142303DOI Listing
January 2019
2 Reads

Triple therapy vs Double Therapy: One Scenario, 8 Questions, lots of conclusions.

Curr Cardiol Rev 2019 Jan 10. Epub 2019 Jan 10.

Department of Medical Biotechnologies, Division of Cardiology, University of Siena, Siena. Italy.

In patients with atrial fibrillation undergoing percutaneous coronary intervention with placement of stents, a triple antithrombotic therapy is empirically established, which consists of the combination of dual antithrombotic therapy (aspirin plus a P2Y12 inhibitor) and an oral anticoagulant agent. This choice is guided by the desirable result of reducing cerebrovascular and coronary ischemic events. However, there is an unwelcome outcome: an increased incidence of bleedings. Read More

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http://dx.doi.org/10.2174/1573403X15666190111095438DOI Listing
January 2019
1 Read

Percutaneous Pulmonary Valve Implantation; current status and future perspectives.

Curr Cardiol Rev 2018 Dec 23. Epub 2018 Dec 23.

Department of Cardiology Division Heart and Lungs University Medical Center Utrecht Room E.01.207 3508 GA Utrecht. Netherlands.

Patients with congenital heart disease (CHD) with right ventricle outflow tract (RVOT) dysfunction need sequential pulmonary valve replacements throughout their life in the majority of cases. Since their introduction in 2000, the number of percutaneous pulmonary valve implantations (PPVI) has grown and reached over 10,000 procedures worldwide. Overall, PPVI has been proven safe and effective, but some anatomical variations can limit procedural success. Read More

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http://dx.doi.org/10.2174/1573403X15666181224113855DOI Listing
December 2018
1 Read

Preface.

Authors:
Jian'an Wang

Curr Cardiol Rev 2019 ;15(1)

The Second Affiliated Hospital Zhejiang University School of Medicine Hangzhou, China.

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http://dx.doi.org/10.2174/1573403X1501181211113024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367694PMC
January 2019
2 Reads

Shock - Classification and Pathophysiological Principles of Therapeutics.

Curr Cardiol Rev 2019 ;15(2):102-113

Department of Cardiology Bluhm Cardiovascular Institute Feinberg School of Medicine Northwestern University Medical Center, Chicago, Illinois, IL, United States.

The management of patients with shock is extremely challenging because of the myriad of possible clinical presentations in cardiogenic shock, septic shock and hypovolemic shock and the limitations of contemporary therapeutic options. The treatment of shock includes the administration of endogenous catecholamines (epinephrine, norepinephrine, and dopamine) as well as various vasopressor agents that have shown efficacy in the treatment of the various types of shock. In addition to the endogenous catecholamines, dobutamine, isoproterenol, phenylephrine, and milrinone have served as the mainstays of shock therapy for several decades. Read More

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http://dx.doi.org/10.2174/1573403X15666181212125024DOI Listing
January 2019
11 Reads

Cryoballoon Ablation for the Treatment of Atrial Fibrillation: A Meta-Analysis.

Curr Cardiol Rev 2018 12 11. Epub 2018 Dec 11.

Division of Cardiology, Brooklyn VA Center, Department of Cardiology, Brooklyn, NY, USA

Background: Ablation therapy is the treatment of choice in antiarrhythmic drug refractory atrial fibrillation (AF). It is performed by either cryoballoon ablation (CBA) or radiofrequency ablation. CBA is gaining popularity due to simplicity with similar efficacy and complication rate compared with RFA. Read More

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http://dx.doi.org/10.2174/1573403X15666181212102419DOI Listing
December 2018
18 Reads

Extensively thrombosed ectatic circumflex coronary artery fistula presenting as acute coronary syndrome.

Curr Cardiol Rev 2018 Dec 6. Epub 2018 Dec 6.

Department of Cardiology, University Heart Center, University Hospital Zurich. Switzerland.

Background: Coronary artery fistula (CAF) is an abnormal communication between the termination of a coronary artery or its branches and a cardiac chamber, a great vessel or other vascular structure. Symptomatic patients with large CAF should undergo surgical or percutanous closure of the fistula at the drainage site while still the debate on closing asymptomatic CAF and re-openening symptomatic occluded CAF is ongoing.

Case Summary: We are reporting a 30-year-old male patient with no previous medical history presented as non-ST segment elevation myocardial Infarction. Read More

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http://dx.doi.org/10.2174/1573403X15666181206120138DOI Listing
December 2018
6 Reads

Gender Differences in Atrial Fibrillation: A Review of Epidemiology, Management, and Outcomes.

Curr Cardiol Rev 2019 ;15(2):136-144

School of Medicine, Emory University, 1639 Pierce Drive, WMB 308 Atlanta, GA 30322, United States.

Atrial fibrillation is the most common sustained cardiac arrhythmia. The scope and impact of atrial fibrillation are wide; it can affect cardiac function, functional status, and quality of life, and it confers a stroke risk. There are sex differences in atrial fibrillation across the scope of the disease process, from epidemiology and causative mechanisms to management and outcomes. Read More

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http://www.eurekaselect.com/168071/article
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http://dx.doi.org/10.2174/1573403X15666181205110624DOI Listing
January 2019
24 Reads

Rate and Predictors of Permanent Pacemaker Implantation after Transcatheter Aortic Valve Implantation: Current Status.

Curr Cardiol Rev 2018 12 4. Epub 2018 Dec 4.

Department of Cardiovascular Disease, Division of Cardiac Surgery, Casa Sollievo della Sofferenza IRCCS, San Giovanni Rotondo. Italy.

Transcather aortic valve implantation (TAVI) has become a safe and indispensable treatment option for patients with severe symptomatic aortic stenosis who are at high surgical risk. Recently, outcomes after TAVI have improved significantly and TAVI has emerged as a qualified alternative to surgical aortic valve replacement in the treatment of intermediate risk patients and greater adoption of this procedure is to be expected in a wider patients population, including younger patients and low surgical risk patients. However since the aortic valve has close spatial proximity to the conduction system, conduction anomalies are frequently observed in TAVI. Read More

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http://dx.doi.org/10.2174/1573403X15666181205105821DOI Listing
December 2018
2 Reads

Effect of S-equol and Soy Isoflavones on Heart and Brain.

Curr Cardiol Rev 2019 ;15(2):114-135

Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, United States.

Background: Observational studies in Asia show that dietary intake of soy isoflavones had a significant inverse association with coronary heart disease (CHD). A recent randomized controlled trial (RCT) of soy isoflavones on atherosclerosis in the US, however, failed to show their benefit. The discrepancy may be due to the much lower prevalence of S-equol producers in Westerners: Only 20-30% of Westerners produce S-equol in contrast to 50-70% in Asians. Read More

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http://dx.doi.org/10.2174/1573403X15666181205104717DOI Listing
January 2019
15 Reads

Adverse Consequences of Right Ventricular Apical Pacing and Novel Strategies to Optimize Left Ventricular Systolic and Diastolic Function.

Curr Cardiol Rev 2019 ;15(2):145-155

Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, Jiangsu Province, China.

Several studies have focused on the deleterious consequences of Right Ventricular Apical (RVA) pacing on Left Ventricular (LV) function, mediated by pacing-induced ventricular dyssynchrony. Therapeutic strategies to reduce the detrimental consequences of RVA pacing have been proposed, that includes upgrading of RVA pacing to Cardiac Resynchronization Therapy (CRT), alternative Right Ventricular (RV) pacing sites, minimal ventricular pacing strategies, as well as atrial-based pacing. In developing countries, single chamber RV pacing still constitutes a majority of cases of permanent pacing, and assessment of the optimal RV pacing site is of paramount importance. Read More

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http://dx.doi.org/10.2174/1573403X15666181129161839DOI Listing
January 2019
3 Reads

Acute Kidney Injury Post Cardiac Catheterization: Does Vascular Access Route Matter?

Curr Cardiol Rev 2019 ;15(2):96-101

Department of Medicine, Einstein Medical Center, Philadelphia, PA 19141, United States.

Background: Acute Kidney Injury as a complication of cardiac catheterization is associated with increased length of hospital stay and mortality. In recent years, the use of the radial artery for cardiac catheterization is increasing in frequency.

Objective: The objective of this concise review was to evaluate the method of cardiac access site and its impact on Acute Kidney Injury following cardiac catheterization. Read More

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http://dx.doi.org/10.2174/1573403X14666181113112210DOI Listing
January 2019
13 Reads

Tissue Non-Specific Alkaline Phosphatase and Vascular Calcification: A Potential Therapeutic Target.

Curr Cardiol Rev 2019 ;15(2):91-95

Fundacion Instituto de Investigacion Sanitaria, Fundacion Jimenez Diaz, Avenida Reyes Catolicos 2, Madrid, Spain.

Vascular calcification is a pathologic phenomenon consisting of calcium phosphate crystal deposition in the vascular walls. Vascular calcification has been found to be a risk factor for cardiovascular diseases, due to its correlation with cardiovascular events and mortality, and it has been associated with aging, diabetes, and chronic kidney disease. Studies of vascular calcification have focused on phosphate homeostasis, primarily on the important role of hyperphosphatemia. Read More

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http://www.eurekaselect.com/166818/article
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http://dx.doi.org/10.2174/1573403X14666181031141226DOI Listing
January 2019
8 Reads

Application of G-CSF in Congestive Heart Failure Treatment.

Curr Cardiol Rev 2019 ;15(2):83-90

Department of Clinical Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.

Introduction: Congestive Heart Failure (CHF) is a disorder in which the heart is unable to supply enough blood for body tissues. Since heart is an adaptable organ, it overcomes this condition by going under remodeling process. Considering cardiac myocytes are capable of proliferation after MI, stimulation of neovascularization as well as their regeneration might serve as a novel target in cardiac remodeling prevention and CHF treatment. Read More

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http://dx.doi.org/10.2174/1573403X14666181031115118DOI Listing
January 2019
5 Reads

Interrelationship Between Kidney Function and Percutaneous Mitral Valve Interventions: A Comprehensive Review.

Curr Cardiol Rev 2019 ;15(2):76-82

Department of Medicine, Einstein Medical Center, Philadelphia, PA, United States.

Percutaneous mitral valve repair is emerging as a reasonable alternative especially in those with an unfavorable surgical risk profile in the repair of mitral regurgitation. At this time, our understanding of the effects of underlying renal dysfunction on outcomes with percutaneous mitral valve repair and the effects of this procedure itself on renal function is evolving, as more data emerges in this field. The current evidence suggests that the correction of mitral regurgitation via percutaneous mitral valve repair is associated with some degree of improvement in cardiac function, hemodynamics and renal function. Read More

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http://dx.doi.org/10.2174/1573403X14666181024155247DOI Listing
January 2019
2 Reads

Ventricular Arrhythmias in Patients with Obstructive Sleep Apnea.

Curr Cardiol Rev 2019 ;15(1):64-74

Cardiology Department, Centro Hospitalar de Setubal, Setubal, Portugal.

Obstructive Sleep Apnea (OSA) is a prevalent condition thought to increase in the future. Being mostly undiagnosed, the most serious complications are cardiovascular diseases, among which are arrhythmias. Controversy remains as to whether OSA is a primary etiologic factor for ventricular arrhythmias, because of the high incidence of cardiovascular comorbidities in OSA patients. Read More

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http://dx.doi.org/10.2174/1573403X14666181012153252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367697PMC
January 2019
9 Reads

Aging - How Lifestyle Changes Could Prove to be an Effective Medicine for the Aging Cardiovascular System.

Authors:
Mark D Ross

Curr Cardiol Rev 2018 ;14(4):225-226

School of Applied Sciences Edinburgh Napier University Edinburgh, United Kingdom.

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http://dx.doi.org/10.2174/1573403X1404181008124415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300800PMC
November 2018
2 Reads

Effects of Pulmonary Hypertension and Right Ventricular Function in Short and Long-Term Kidney Function.

Curr Cardiol Rev 2019 ;15(1):3-11

Department of Medicine, Albert Einstein Medical Center, Philadelphia, PA, United States.

Background: Pulmonary hypertension is not uncommon in patients with renal disease and vice versa; therefore, it influences treatments and outcomes. There is a large body of literature on pulmonary hypertension in patients with kidney disease, its prognostic implications, economic burden, and management strategies. However, the converse, namely the hemodynamic effects of pulmonary hypertension on kidney function (acute and chronic kidney injury) is less studied and described. Read More

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http://dx.doi.org/10.2174/1573403X14666181008154215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367698PMC
January 2019
3 Reads

Role of Cardiac Magnetic Resonance Imaging in Patients with Idiopathic Ventricular Arrhythmias.

Curr Cardiol Rev 2019 ;15(1):12-23

Flinders University, Bedford Park, Adelaide, Australia.

Ventricular Arrhythmias (VAs) may present with a wide spectrum of clinical manifestations ranging from mildly symptomatic frequent premature ventricular contractions to lifethreatening events such as sustained ventricular tachycardia, ventricular fibrillation and sudden cardiac death. Myocardial scar plays a central role in the genesis and maintenance of re-entrant arrhythmias which are commonly associated with Structural Heart Diseases (SHD) such as ischemic heart disease, healed myocarditis and non-ischemic cardiomyopathies. However, the arrhythmogenic substrate may remain unclear in up to 50% of the cases after a routine diagnostic workup, comprehensive of 12-lead surface ECG, transthoracic echocardiography and coronary angiography/ computed tomography. Read More

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http://dx.doi.org/10.2174/1573403X14666180925095923DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367696PMC
January 2019
7 Reads

Basic Concepts of Contrast Injection Protocols for Coronary Computed Tomography Angiography.

Curr Cardiol Rev 2019 ;15(1):24-29

Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjyo, Chuo-ku, Kumamoto, 860-8556, Japan.

Background: Coronary Computed Tomography Angiography (CTA) has become one of the most important diagnostic imaging modalities for the evaluation of coronary artery diseases. During coronary computed CTA, sufficient vascular enhancement is essential for the accurate detection and evaluation of lesions in the coronary arteries. To obtain optimal contrast enhancement and perform appropriate clinical coronary CTA, physicians, radiologists, and radiology technologists should acquire a basic knowledge of contrast injection protocols. Read More

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http://dx.doi.org/10.2174/1573403X14666180918102031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367701PMC
January 2019
1 Read

Electrocardiographic Assessment and Genetic Analysis in Neonates: a Current Topic of Discussion.

Curr Cardiol Rev 2019 ;15(1):30-37

Medical Science Department, School of Medicine, University of Girona, Girona, Spain.

Background: Sudden death of a newborn is a rare entity, which may be caused by genetic cardiac arrhythmias. Among these diseases, Long QT syndrome is the most prevalent arrhythmia in neonates, but other diseases such as Brugada syndrome, Short QT syndrome and Catecholaminergic Polymorphic Ventricular Tachycardia also cause sudden death in infants. All these entities are characterized by well-known alterations in the electrocardiogram and the first symptom of the disease may be an unexpected death. Read More

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http://dx.doi.org/10.2174/1573403X14666180913114806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367699PMC
January 2019
23 Reads

Similarities and Differences Between Carotid Artery and Coronary Artery Function.

Curr Cardiol Rev 2018 ;14(4):254-263

Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, United Kingdom.

Background: Cardiovascular Disease (CVD) remains one of the leading causes of morbidity and mortality. Strategies to predict development of CVD are therefore key in preventing and managing CVD. One stratergy in predicting CVD is by examining the role of traditional risk factors for CVD (e. Read More

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http://www.eurekaselect.com/165242/article
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http://dx.doi.org/10.2174/1573403X14666180910125638DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300794PMC
November 2018
3 Reads

Cellular Mechanisms of Valvular Thickening in Early and Intermediate Calcific Aortic Valve Disease.

Curr Cardiol Rev 2018 ;14(4):264-271

School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, 70211 Kuopio, Finland.

Background: Calcific aortic valve disease is common in an aging population. It is an active atheroinflammatory process that has an initial pathophysiology and similar risk factors as atherosclerosis. However, the ultimate disease phenotypes are markedly different. Read More

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http://dx.doi.org/10.2174/1573403X14666180820151325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300797PMC
November 2018
2 Reads

Cardiac Response to Exercise in Normal Ageing: What Can We Learn from Masters Athletes?

Curr Cardiol Rev 2018 ;14(4):245-253

Institute of Clinical Exercise and Health Science, University of the West of Scotland, G72 0LH, Scotland.

Background: Ageing is associated with an inexorable decline in cardiac and vascular function, resulting in an increased risk of Cardiovascular Disease (CVD). Lifestyle factors such as exercise have emerged as a primary therapeutic target in the prevention of CVD, yet older individuals are frequently reported as being the least active, with few meeting the recommended physical activity guidelines. In contrast, well trained older individuals (Masters athletes) have superior functional capacity than their sedentary peers and are often comparable with young non-athletes. Read More

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http://dx.doi.org/10.2174/1573403X14666180810155513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300801PMC
November 2018
12 Reads

Arterial Aging, Metalloproteinase Regulation, and the Potential of Resistance Exercise.

Authors:
Allan Knox

Curr Cardiol Rev 2018 ;14(4):227-232

Exercise Science Department, California Lutheran University, 60 Olsen Road, Thousand Oaks, CA, United States.

Background: Aging is a process that affects all living organisms. The transition through life elicits tissue specific alterations in the functional and structural capabilities of all physiological systems. In particular, the vasculature is vulnerable to aging specific adaptations which induces morphological changes and ultimately increases the risk of pathological states. Read More

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http://dx.doi.org/10.2174/1573403X14666180801153801DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300795PMC
November 2018
7 Reads

Endothelial Regenerative Capacity and Aging: Influence of Diet, Exercise and Obesity.

Authors:
Mark D Ross

Curr Cardiol Rev 2018 ;14(4):233-244

School of Applied Sciences, Edinburgh Napier University, Edinburgh, United Kingdom.

Background: The endothelium plays an important role in cardiovascular regulation, from blood flow to platelet aggregation, immune cell infiltration and demargination. A dysfunctional endothelium leads to the onset and progression of Cardiovascular Disease (CVD). The aging endothelium displays significant alterations in function, such as reduced vasomotor functions and reduced angiogenic capabilities. Read More

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http://dx.doi.org/10.2174/1573403X14666180726112303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300798PMC
November 2018
3 Reads

Subcutaneous Implantable Cardioverter Defibrillators: An Overview of Implantation Techniques and Clinical Outcomes.

Authors:
Bandar Al-Ghamdi

Curr Cardiol Rev 2019 ;15(1):38-48

Heart Center, College of Medicine, King Faisal Specialist Hospital & Research Centre, Zahrawi St, Al Maather, Riyadh 12713, Saudi Arabia.

Sudden Cardiac Death (SCD) is a significant health problem worldwide. Multiple randomized controlled trials have shown that Implantable Cardioverter Defibrillators (ICDs) are effective life-saving management option for individuals at risk of SCD in both primary and secondary prevention. Although the conventional transvenous ICDs (TV-ICDs) are safe and effective, there are potential complications associated with its use, including localized pocket or wound infection or systematic infection, a vascular access related complication such as pneumothorax, and venous thrombosis, and lead related complications such as dislodgement, malfunction, and perforation. Read More

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http://dx.doi.org/10.2174/1573403X14666180716164740DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367695PMC
January 2019
36 Reads

Autoantibodies for Cardiac Channels and Sudden Cardiac Death and its Relationship to Autoimmune Disorders.

Curr Cardiol Rev 2019 ;15(1):49-54

Division of Cardiovascular Medicine, SUNY Downstate Medical Center, 470 Clarkson Avenue, Brooklyn, NY, 11203, United States.

Background: Sudden Cardiac Death (SCD) is an unexpected death caused by heart dysfunction. Autoantibodies against cardiac proteins may be potentially involved in the occurrence and progression of cardiac disease and SCD. The first report on the role of autoantibodies in idiopathic dilated cardiomyopathy appeared in the 1980s. Read More

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http://www.eurekaselect.com/163774/article
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http://dx.doi.org/10.2174/1573403X14666180716095201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367693PMC
January 2019
20 Reads

Interventional Cardiologist Approach to Cardiac Arrest.

Authors:
K Lotun K B Kern

Curr Cardiol Rev 2018 ;14(2):78

Division of Cardiology University of Arizona Tucson, AZ, United States.

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http://dx.doi.org/10.2174/1573403X1402180705163831DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088449PMC
January 2018
3 Reads

Chronic Kidney Disease and Cardiovascular Disease: Is there Any Relationship?

Curr Cardiol Rev 2019 ;15(1):55-63

Evangelismos General Hospital, 45-47 Ipsilantou str, Athens, Greece.

Introduction: Chronic Kidney Disease is a growing health burden world wide. Traditional and mutual risk factors between CVD and CKD are age, hypertension, diabetes mellitus, dyslipidemia, tobacco use, family history and male gender. In this review, we will focus on whether or not early CKD is an important risk factor for the presence, severity and progression of CVD. Read More

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http://dx.doi.org/10.2174/1573403X14666180711124825DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367692PMC
January 2019
3 Reads

Reactive Oxygen Species as Intracellular Signaling Molecules in the Cardiovascular System.

Curr Cardiol Rev 2018 ;14(4):290-300

Department of Physiology and Cell Biology, College of Medicine, University of South Alabama, Mobile, AL, United States.

Background: Redox signaling plays an important role in the lives of cells. This signaling not only becomes apparent in pathologies but is also thought to be involved in maintaining physiological homeostasis. Reactive Oxygen Species (ROS) can activate protein kinases: CaMKII, PKG, PKA, ERK, PI3K, Akt, PKC, PDK, JNK, p38. Read More

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http://dx.doi.org/10.2174/1573403X14666180702152436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300799PMC
November 2018
8 Reads

The Protective Role of Crocus Sativus L. (Saffron) Against Ischemia- Reperfusion Injury, Hyperlipidemia and Atherosclerosis: Nature Opposing Cardiovascular Diseases.

Curr Cardiol Rev 2018 ;14(4):272-289

First Department of Pediatrics, National and Kapodistrian University of Athens, Choremeio Research Laboratory, Hematology/ Oncology Unit, Thivon & Levadeias, 11527, Athens, Greece.

Background: Reactive oxygen species and reactive nitrogen species, which are collectively called reactive oxygen-nitrogen species, are inevitable by-products of cellular metabolic redox reactions, such as oxidative phosphorylation in the mitochondrial respiratory chain, phagocytosis, reactions of biotransformation of exogenous and endogenous substrate in endoplasmic reticulum, eicosanoid synthesis, and redox reactions in the presence of metal with variable valence. Among medicinal plants, there is growing interest in Crocus Sativus L. It is a perennial, stemless herb, belonging to Iridaceae family, cultivated in various countries such as Greece, Italy, Spain, Israel, Morocco, Turkey, Iran, India, China, Egypt and Mexico. Read More

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http://dx.doi.org/10.2174/1573403X14666180628095918DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300793PMC
November 2018
18 Reads

Clinical Utility of Cardiac Magnetic Resonance Imaging in Pericardial Diseases.

Curr Cardiol Rev 2018 ;14(3):200-212

Division of Cardiology, Center for Cardiac MRI. Allegheny General Hospital, East North Ave, Pittsburgh, PA, United States.

Background: Pericardial diseases are relatively common in clinical practice and encountered in various clinical settings with consequent significant morbidity and mortality. However, the diagnosis as well as management can be complex and challenging, as the clinical presentation is usually non-specific. Therefore, there is an increasing role for Cardiac Magnetic Resonance Imaging (CMR) as an imaging tool to facilitate the diagnosis of pericardial diseases. Read More

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http://dx.doi.org/10.2174/1573403X14666180619104515DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131401PMC
September 2018
5 Reads

Role of Bisphosphonates in Vascular calcification and Bone Metabolism: A Clinical Summary.

Curr Cardiol Rev 2018 ;14(3):192-199

Department of Nephrology, Einstein Medical Center, Sidney Kimmel College of Thomas Jefferson University, Philadelphia, PA, United States.

Background: Vascular calcification is known to be a strong risk factor for cardiovascular adverse events and mortality. Atherosclerosis, diabetes, aging, abnormal bone mineral homeostasis and high uremic milieu such as chronic kidney disease are major factors that contribute to the progression of vascular calcification. Several mechanisms such as the osteoblastic transition of vascular smooth muscle cells in response to oxidative stress have shed light on the active nature of vascular calcification, which was once thought to be a passive process. Read More

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http://dx.doi.org/10.2174/1573403X14666180619103258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131409PMC
September 2018
10 Reads

Use of Bipolar Radiofrequency Catheter Ablation in the Treatment of Cardiac Arrhythmias.

Curr Cardiol Rev 2018 ;14(3):185-191

International Clinical Research Center, St. Anne`s University Hospital Brno, Brno, Czech Republic and Faculty of Medicine, Masaryk University, Brno, Czech Republic.

Background: Arrhythmia management is a complex process involving both pharmacological and non-pharmacological approaches. Radiofrequency ablation is the pillar of nonpharmacological arrhythmia treatment. Unipolar ablation is considered to be the gold standard in the treatment of the majority of arrhythmias; however, its efficacy is limited to specific cases. Read More

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http://dx.doi.org/10.2174/1573403X14666180524100608DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131405PMC
September 2018
2 Reads

Rotational Atherectomy in Acute STEMI with Heavily Calcified Culprit Lesion is a Rule Breaking Solution.

Curr Cardiol Rev 2018 ;14(3):213-216

Department of Cardiology, University Heart Center, University Hospital Zurich, Zurich, Switzerland.

Background: Calcified coronary lesions represent technical challenges during percutaneous coronary intervention and are associated with a high frequency of restenosis and target lesion revascularization. Rotational atherectomy has been shown to increase procedural success in severely calcified lesions, facilitate stent delivery in undilatable lesions and ensure complete stent expansion. However, rotational atherectomy in ST-elevation Myocardial Infarction (STEMI) is traditionally avoided given the concern for slow or no reflow and considered a contraindication in lesions with a visible thrombus by its manufacturer (Rotablator, Boston Scientific). Read More

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http://dx.doi.org/10.2174/1573403X14666180523084846DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131400PMC
September 2018
3 Reads

Triple-Valve Endocarditis in a Diabetic Patient: Case Report and Literature Review.

Curr Cardiol Rev 2018 ;14(3):217-224

Baystate Medical Center, University of Massachusetts Medical School, Springfield, MA, United States.

Background: Despite major advancements since its first description in the 19th century, infective endocarditis remains a significant medical challenge. Although commonly involving a single valve, multiple valve involvement may occur, complicating matters even further. Triplevalve endocarditis is a very rare phenomenon. Read More

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http://dx.doi.org/10.2174/1573403X14666180522124621DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131402PMC
September 2018
2 Reads

Role of Cardiac Catheterization Lab Post Resuscitation in Patients with ST Elevation Myocardial Infarction.

Curr Cardiol Rev 2018 ;14(2):85-91

Sarver Heart Center, University of Arizona, Tucson, AZ, United States.

Background: Cardiac arrest remains a common and lethal condition associated with high morbidity and mortality. Even with improving survival rates, the successfully resuscitated post cardiac arrest patient is also at risk for poor neurological outcomes, functional status and long- term survival if not managed appropriately. Given that acute coronary occlusion has been found to be the leading cause of cardiac arrest, long-term prognosis is good in selected patients after successful outof- hospital resuscitation and ST elevation myocardial infarction who are taken for immediate coronary angiography, treated with primary percutaneous coronary intervention and hypothermia when indicated. Read More

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http://dx.doi.org/10.2174/1573403X14666180517080828DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088447PMC
September 2018
2 Reads