217,049 results match your criteria Culture health & sexuality[Journal]


[Predictive value of white blood cell, procalcitonin and high-sensitivity C-reactive protein for the bloodstream infection in the super-elderly critically-ill patients].

Zhonghua Yi Xue Za Zhi 2019 Jan;99(5):365-369

Department of Critical Care Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China.

To investigate the ability of white blood cell (WBC), procalcitonin (PCT) and high-sensitivity C-reactive protein (hs-CRP) in the super-elderly patients with bloodstream infection. It was a retrospective study. A total of 77 patients (≥85 years) admitted to the ICU of Peking Union Medical College Hospital from June, 2016 to December, 2017 were enrolled. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.05.009DOI Listing
January 2019
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Antioxidative enzymes activity and thiol metabolism in three leafy vegetables under Cd stress.

Ecotoxicol Environ Saf 2019 Feb 14;173:214-224. Epub 2019 Feb 14.

Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, China.

The enrichment of Cadmium in vegetables is threatening human health. The study aimed to screen Cd low-enriched leafy vegetables and explore whether antioxidative enzymes and heavy metal chelators are synergistic defensive mechanisms. In this paper, the Cd accumulation and translocation of garland chrysanthemum (Chrysanthemum coronarium L. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01476513193017
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http://dx.doi.org/10.1016/j.ecoenv.2019.02.026DOI Listing
February 2019
1 Read

Valorization of crude glycerol based on biological processes for accumulation of lipophilic compounds.

Int J Biol Macromol 2019 Feb 14. Epub 2019 Feb 14.

Department of Bromatological Analysis, College of Pharmacy, Federal University of Bahia, Salvador, Bahia, Brazil.

Bacteria that are capable of accumulating lipids in their cells as storage compounds can also produce polyhydroxyalkanoates of high technological value, depending on the specific culture conditions. The objective of this study was to utilize crude glycerol from biodiesel (CGB) as a substrate, which is a major byproduct from biodiesel production, to produce lipophilic compounds. Bacillus megaterium INCQS 425 was cultivated and evaluated for the production of lipophilic compounds and the properties of these compounds were investigated. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.02.077DOI Listing
February 2019

Mesenchymal stem cells isolated from both distal femurs of patients with unilateral trauma or osteoarthritis of the knee exhibit similar in-vitro ability of bone formation.

J Orthop Sci 2019 Feb 13. Epub 2019 Feb 13.

Department of Orthopedic Surgery and Sports Traumatology, Odense University Hospital, J. B. Winsløvsvej 4, Odense C, 5000, Denmark. Electronic address:

Background: Bone fractures are a common cause of hospital admission. Currently, treatment consists of conservative regimens or operation. However, regenerative medicine introduces a possible new addition to established treatments. Read More

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http://dx.doi.org/10.1016/j.jos.2019.01.008DOI Listing
February 2019

Effect of pre-maturation with C-type natriuretic peptide and 3-isobutyl-1-methylxanthine on cumulus-oocyte communication and oocyte developmental competence in cattle.

Anim Reprod Sci 2019 Mar 25;202:49-57. Epub 2019 Jan 25.

Robinson Research Institute, School of Paediatrics and Reproductive Health, The University of Adelaide, Adelaide, South Australia, 5005, Australia; Adelaide Medical School, The University of Adelaide, Adelaide, South Australia, 5005, Australia; Australian Research Council Centre of Excellence for Nanoscale BioPhotonics and Institute for Photonics and Advanced Sensing, The University of Adelaide, Adelaide, South Australia, 5005, Australia. Electronic address:

In vitro embryo production depends on oocyte competence, which is acquired during folliculogenesis, involving cytoplasmic and nuclear processes. In vitro maturation (IVM) induces spontaneous resumption of meiosis, preventing full competence acquisition. The incorporation of a pre-IVM phase with supplementation with C-type natriuretic peptide (CNP) and 3-Isobutyl-1-methylxanthine (IBMX) was used with the aim of improving developmental competence of cattle oocytes. Read More

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http://dx.doi.org/10.1016/j.anireprosci.2019.01.007DOI Listing

Impact of the introduction of the Haemophilus influenzae type b conjugate vaccine in an urban setting in southern India.

Vaccine 2019 Feb 13. Epub 2019 Feb 13.

Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21218, USA.

Introduction: Haemophilus influenzae type b was the leading cause of bacterial meningitis in infants and children below the age of two years prior to the introduction of H. influenzae type b conjugate vaccines. In December 2011, the Indian government introduced H. Read More

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http://dx.doi.org/10.1016/j.vaccine.2019.01.080DOI Listing
February 2019

Technical note: Bovine adipocyte and preadipocyte co-culture as an efficient adipogenic model.

J Dairy Sci 2019 Feb 13. Epub 2019 Feb 13.

Department of Large Animal Clinical Sciences, Michigan State University, East Lansing 48824. Electronic address:

Reductionist studies of adipose tissue biology require reliable in vitro adipocyte culturing models. Current protocols for adipogenesis induction in stromal vascular fraction-derived preadipocytes require extended culturing periods and have low adipogenic rates. We compared the adipogenic efficiency of a 7-d co-culture model of visceral (VIS) and subcutaneous (SC) stromal vascular fraction-derived preadipocytes with mature adipocytes with a 14-d standard adipocyte differentiation protocol. Read More

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http://dx.doi.org/10.3168/jds.2018-15626DOI Listing
February 2019

Risk factors of clinical mastitis and antimicrobial susceptibility test results of mastitis milk from dairy cattle in western Thailand: Bayesian network analysis.

Prev Vet Med 2019 Mar 1;164:49-55. Epub 2019 Feb 1.

Section of Epidemiology, Department of Veterinary Public Health, Faculty of Veterinary Medicine, Kasetsart University, Kamphaeng Saen, Nakhon Pathom, 73140, Thailand. Electronic address:

Using Bayesian network analysis, this cross-sectional study aimed to identify the conditional probability among dairy farm practices, cow characteristics, bacteriological culture results, and antimicrobial susceptibility test results of milk from dairy cows with clinical mastitis in western Thailand. Data associated with risk factors and clinical signs were collected using a structured questionnaire that was administered to 34 small dairy holders. In total, 100 quarters of milk samples from 100 cows were used for Bayesian network analysis. Read More

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http://dx.doi.org/10.1016/j.prevetmed.2019.01.014DOI Listing

Spondylodiscitis in end-stage renal disease: a systematic review.

J Neurosurg Spine 2019 Feb 15:1-9. Epub 2019 Feb 15.

1Department of Neurological Surgery, University of Miami, Miami, Florida; and.

OBJECTIVEDiscitis and osteomyelitis are seen in end-stage renal disease (ESRD) patients due to repeated vascular access for hemodialysis and urinary tract infections leading to recurrent bacteremia. Discitis and osteomyelitis are underdiagnosed due to the nonspecific initial presentation of back pain. In this article, we review the literature for better understanding of the problem and the importance of early diagnosis by primary care physicians and nephrologists. Read More

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http://dx.doi.org/10.3171/2018.9.SPINE18824DOI Listing
February 2019

Regulatory T lymphocytes are associated with increased nasopharyngeal colonization in children.

Int J Pediatr Otorhinolaryngol 2019 Feb 5;120:51-57. Epub 2019 Feb 5.

Office of Senior DVC and Provost, Swinburne University of Technology, Melbourne, Australia. Electronic address:

Objectives: Regulatory T lymphocytes (T) have been linked to survival of commensal bacteria at mucosal sites, but their presence and role in chronic otitis media (COM) and their response to otopathogens has not been evaluated previously. We investigated the association between T lymphocytes and otopathogens in COM prone and non-COM prone children.

Methods: Forty children, 2-7 years of age, scheduled for adenoidectomy were enrolled into COM (n = 20) or non-COM (n = 20) groups. Read More

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http://dx.doi.org/10.1016/j.ijporl.2019.02.011DOI Listing
February 2019

Anticancer and antimetastatic potential of enterolactone: clinical, preclinical and mechanistic perspectives.

Eur J Pharmacol 2019 Feb 13. Epub 2019 Feb 13.

Pharmaceutical Sciences, Poona College of Pharmacy, Bharati Vidyapeeth (Deemed to be University), Pune, Maharashtra 411038, India.

Currently cancer is the second leading cause of death globally and worldwide incidence and mortality rates of all cancers of males and females are rising tremendously. In spite of advances in chemotherapy and radiation, metastasis and recurrence are considered as the major causes of cancer related deaths. Hence there is a mounting need to develop new therapeutic modalities to treat metastasis and recurrence in cancers. Read More

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http://dx.doi.org/10.1016/j.ejphar.2019.02.022DOI Listing
February 2019

The joint impact of smoking plus alcohol drinking on treatment of pulmonary tuberculosis.

Eur J Clin Microbiol Infect Dis 2019 Feb 15. Epub 2019 Feb 15.

Beijing Chest Hospital, Capital Medical University, Machang Road, No. 97, Beijing, 101149, China.

Tuberculosis, smoking, and alcohol drinking are major public health and social issues worldwide. We investigated the joint effect of smoking plus alcohol drinking on TB treatment. Retrospective study was conducted among TB patients in 49 units from eight provinces in China. Read More

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http://dx.doi.org/10.1007/s10096-019-03489-zDOI Listing
February 2019

Impact of a Heat Shock Protein Impurity on the Immunogenicity of Biotherapeutic Monoclonal Antibodies.

Pharm Res 2019 Feb 15;36(4):51. Epub 2019 Feb 15.

School of Biological Sciences, Faculty of Biology Medicine and Health Manchester Academic Health Science Centre, The University of Manchester, Michael Smith Building Oxford Road, Manchester, M13 9PT, UK.

Purpose: Anti-drug antibodies can impair the efficacy of therapeutic proteins and, in some circumstances, induce adverse health effects. Immunogenicity can be promoted by aggregation; here we examined the ability of recombinant mouse heat shock protein 70 (rmHSP70) - a common host cell impurity - to modulate the immune responses to aggregates of two therapeutic mAbs in mice.

Methods: Heat and shaking stress methods were used to generate aggregates in the sub-micron size range from two human mAbs, and immunogenicity assessed by intraperitoneal exposure in BALB/c mice. Read More

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http://dx.doi.org/10.1007/s11095-019-2586-7DOI Listing
February 2019

The effect of L-theanine supplementation on the immune system of athletes exposed to strenuous physical exercise.

J Int Soc Sports Nutr 2019 Feb 15;16(1). Epub 2019 Feb 15.

Department of Morphological and Health Sciences, Faculty of Physical Culture in Gorzów Wielkopolski, 13 Estkowskiego Str, 66-400, Gorzów Wielkopolski, Poland.

Background: The aim of this study was to analyze the response of selected components of the immune system in rowers to maximal physical exercise, and to verify if this response could be modulated by supplementation with L-theanine.

Method: The double-blind study included 20 members of the Polish Rowing Team. The subjects were randomly assigned to the supplemented group (n = 10), receiving 150 mg of L-theanine extract for 6 weeks, or to the placebo group (n = 10). Read More

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http://dx.doi.org/10.1186/s12970-019-0274-yDOI Listing
February 2019

Replication competence of virions induced from CD4+ lymphocytes latently infected with HIV.

Retrovirology 2019 Feb 15;16(1). Epub 2019 Feb 15.

San Diego Veterans Affairs Healthcare System, San Diego, CA, USA.

Latently infected CD4 lymphocytes preclude cure of HIV infection, even with the most effective antiretroviral therapy. The replication competent latent HIV reservoir has been quantified with the terminal dilution quantitative viral outgrowth assay, which induces virus propagation in CD4 T cell culture supernatants following cellular activation. Efforts to improve the sensitivity of this inefficient assay have introduced more sensitive p24 ELISA and RNA PCR based endpoints, but these more sensitive endpoints have raised the question whether they are measuring induced replication competent or defective virions. Read More

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http://dx.doi.org/10.1186/s12977-019-0466-1DOI Listing
February 2019

A co-produced method to involve service users in research: the SUCCESS model.

BMC Med Res Methodol 2019 Feb 15;19(1):34. Epub 2019 Feb 15.

Centre for Innovative Ageing, College of Human and Health Science, Swansea University, Swansea, UK.

Background: Public and patient involvement is a routine element of health services research methods to produce better designed and reported studies. Although co-production is recommended when involving people in research, methods for involving people are usually designed and managed by researchers and there is little evidence about methods to co-produce models for effective public and patient involvement. We report the method used by a group of patient and carer service users to develop and implement a model for involving public members in research. Read More

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http://dx.doi.org/10.1186/s12874-019-0671-6DOI Listing
February 2019

Development and validation of the European QUALity (EQUAL) score for mucormycosis management in haematology.

J Antimicrob Chemother 2019 Feb 15. Epub 2019 Feb 15.

Department I for Internal Medicine, Excellence Centre for Medical Mycology (ECMM), University Hospital Cologne, Cologne, Germany.

Background: Mucormycosis is a life-threatening infection in immunocompromised patients and in haematological malignancy patients in particular.

Objectives: Our aim was to develop and evaluate a scoring tool to measure adherence to current guidelines for mucormycosis.

Methods: Current guidelines of scientific societies on mucormycosis management were reviewed. Read More

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http://dx.doi.org/10.1093/jac/dkz051DOI Listing
February 2019

High Hydrostatic Pressure Processing Better Preserves the Nutrient and Bioactive Compound Composition of Human Donor Milk.

J Nutr 2019 Feb 15. Epub 2019 Feb 15.

Department of Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada.

Background: When mother's milk is insufficient, pasteurized human donor milk (DM) is the recommended supplement for hospitalized very-low-birth-weight infants. The current method of pasteurization (Holder, 62.5°C, 30 min) negatively affects heat-sensitive nutrients and bioactive proteins. Read More

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http://dx.doi.org/10.1093/jn/nxy302DOI Listing
February 2019

The endometrium during and after ovarian hyperstimulation and the role of segmentation of infertility treatment.

Best Pract Res Clin Endocrinol Metab 2018 Sep 13. Epub 2018 Sep 13.

Department of Reproductive Medicine, Dexeus University Hospital, Barcelona, Spain; Department of Clinical Medicine, Faculty of Health, Aarhus University, Aarhus, Denmark; Faculty of Medicine and Pharmacy, Department of Surgical and Clinical Science, Vrije Universiteit Brussel, Brussels, Belgium. Electronic address:

Controlled ovarian hyperstimulation (COH) is a crucial part of assisted reproductive technologies (ART) that resulted in a substantial increase in pregnancy rates from in vitro fertilization (IVF). However, in spite of the apparent benefit of COH on an increase in the number of follicles and the number of oocytes retrieved, allowing for extended embryo culture and enabling the selection of the best quality embryo for transfer, several reports has shown that the supraphysiologic hormonal levels may indeed have a detrimental effect at the endometrial level. The current article revises the pathophysiological mechanisms through which ovarian stimulation may negatively affect endometrial receptivity. Read More

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http://dx.doi.org/10.1016/j.beem.2018.09.003DOI Listing
September 2018

What Matters Most for Community Social Capital among Older Adults Living in Urban China: The Role of Health and Family Social Capital.

Int J Environ Res Public Health 2019 Feb 15;16(4). Epub 2019 Feb 15.

Department of Social Work, School of Sociology and Population Studies, Renmin University of China, Beijing 100872, China.

The present study investigated individual-level determinants of community social capital among older adults in urban China, with a particular emphasis on health and family social capital. A quota sampling method was used to select 456 adults aged 60 or older from 16 local communities in the city of Suzhou in 2015. Multiple indicators and multiple courses in structural equation modeling were used to examine the proposed model. Read More

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http://dx.doi.org/10.3390/ijerph16040558DOI Listing
February 2019

Towards the development of standardised sea turtle primary cell cultures for toxicity testing.

Ecotoxicol Environ Saf 2019 Feb 12;173:63-70. Epub 2019 Feb 12.

Australian Rivers Institute, School of Environment and Science, Griffith University, Gold Coast, Australia.

Chemical contaminants are known to accumulate in marine megafauna globally, but little is known about how this impacts animal health. In vitro assays offer an ethical, reproducible and cost-effective alternative to live animal toxicity testing on large, long-lived or threatened species, such as sea turtles. However, using a cell culture from a single animal raise the question of whether the toxicity observed adequately represents the toxicity in that species. Read More

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http://dx.doi.org/10.1016/j.ecoenv.2019.01.117DOI Listing
February 2019

miR-3099 promotes neurogenesis and inhibits astrogliogenesis during murine neural development.

Gene 2019 Feb 12. Epub 2019 Feb 12.

Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia; Genetics and Regenerative Medicine Research Centre, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia. Electronic address:

MicroRNA-3099 is highly expressed during neuronal differentiation and development of the central nervous system. Here we characterised the role of miR-3099 during neural differentiation and embryonic brain development using a stable and regulatable mouse embryonic stem cell culture system for miR-3099 expression and in utero electroporation of miR-3099 expression construct into E15.5 embryonic mouse brains. Read More

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http://dx.doi.org/10.1016/j.gene.2019.02.014DOI Listing
February 2019

Rho-inhibition and neuroprotective effect on rotenone-treated dopaminergic neurons in vitro.

Neurotoxicology 2019 Feb 12. Epub 2019 Feb 12.

Department of Translational Research and of New Surgical and Medical Technologies, via Roma 55, University of Pisa, 56126 Pisa, Italy. Electronic address:

Mesencephalic cell cultures are a good model to study the vulnerability of dopaminergic neurons and reproduce, in vitro, experimental models of Parkinson's disease. Rotenone associated as an environmental neurotoxin related to PD, is able to provoke dopaminergic neuron degeneration by inhibiting complex I of the mitochondrial respiratory chain and by inducing accumulation of α-synuclein. Recently, rotenone has been described to activate RhoA, a GTPase protein. Read More

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http://dx.doi.org/10.1016/j.neuro.2019.02.006DOI Listing
February 2019

Traditional Chinese Medicine Enhances Growth, Immune Response, and Resistance to Streptococcus agalactiae in Nile Tilapia.

J Aquat Anim Health 2019 Feb 15. Epub 2019 Feb 15.

Langye Animal Husbandry Company Limited, Gaozhou City, Guangdong Province, China.

Herbal supplements are suitable for improving fish health and combating diseases in fish culture. However, the mechanism of action of many herbal mixtures remains unclear. This study was conducted to evaluate the effects of traditional Chinese medicine (TCM; a mix of Astragalus membranaceus, Angelica sinensis, and Crataegus hupehensis at a ratio of 1:1:1 on a weight basis) on growth, immune response, and disease resistance in Nile tilapia Oreochromis niloticus. Read More

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http://dx.doi.org/10.1002/aah.10049DOI Listing
February 2019

Influence of occlusal deterioration considering prosthetics on subsequent all-cause mortality in a Japanese elderly independent population.

Gerodontology 2019 Feb 15. Epub 2019 Feb 15.

Department of Oral Health Science, Division of Preventive Dentistry, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.

Purpose: The influence of occlusal deterioration on mortality may be incorrectly estimated due to improvements in the occlusal condition with prosthetics or deterioration without prosthetics. The purpose of this study was to evaluate the influence of occlusion cross-sectional status and longitudinal changes considering prosthetics for subsequent all-cause mortality in an elderly population.

Methods: Two dental examinations, in 1999 and 2003, were conducted in 378 subjects aged 71 years old in 1999. Read More

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http://dx.doi.org/10.1111/ger.12394DOI Listing
February 2019

Improving pediatric emergency department physicians' adherence to clinical practice guidelines on the diagnosis and management of group A beta-hemolytic streptococcal pharyngitis-a cross-sectional study.

Int J Emerg Med 2018 16;11:49. Epub 2018 Nov 16.

4Department of Pediatric Emergency, College of Medicine, King Saud bin Abdulaziz University for Health Sciences (KSAUHS), Riyadh, Saudi Arabia.

Introduction: Pharyngitis is one of the major and commonly seen presentations in pediatric emergency departments. While it could be caused by both bacterial and viral pathogens, antibiotics are improperly prescribed regardless of the pathogen. Inappropriate usage of antibiotics has risen the concern of microbial resistance and the need for stricter guidelines. Read More

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http://dx.doi.org/10.1186/s12245-018-0209-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326116PMC
November 2018
1 Read

Trichomonas vaginalis virus (TVV) among women with trichomoniasis and associations with demographics, clinical outcomes, and metronidazole resistance.

Clin Infect Dis 2019 Feb 15. Epub 2019 Feb 15.

Division of Infectious Diseases, University of Alabama at Birmingham.

Background: Trichomonas vaginalis virus (TVV) is a non-segmented, 4.5-5.5 kbp, double-stranded RNA virus infecting T. Read More

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http://dx.doi.org/10.1093/cid/ciz146DOI Listing
February 2019

Association of a blood culture utilization intervention on antibiotic use in a pediatric intensive care unit.

Infect Control Hosp Epidemiol 2019 Feb 15:1-3. Epub 2019 Feb 15.

Division of Pediatric Infectious Diseases,Johns Hopkins School of Medicine,Baltimore, Maryland.

Blood cultures are essential for the evaluation of sepsis. However, they may sometimes be obtained inappropriately, leading to high false-positive rates, largely due to contamination.1 As a quality improvement project, clinician decision-support tools for evaluating patients with fever or signs and symptoms of sepsis were implemented in April 2014 in our pediatric intensive care unit (PICU). Read More

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http://dx.doi.org/10.1017/ice.2019.10DOI Listing
February 2019

The Impact of the Physical Environment on Intrapartum Maternity Care: Identification of Eight Crucial Building Spaces.

HERD 2019 Feb 15:1937586719826058. Epub 2019 Feb 15.

5 School of Nursing and Midwifery, Trinity College Dublin, Dublin, Ireland.

Objectives, Purpose, Or Aim:: This article investigates whether the physical environment in which childbirth occurs impacts the intrapartum intervention rates and how this might happen. The study explores the spatial physical characteristics that can support the design of spaces to promote the health and well-being of women, their supporters, and maternity care professionals.

Background:: Medical interventions during childbirth have consequences for the health of women and babies in the immediate and long term. Read More

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http://dx.doi.org/10.1177/1937586719826058DOI Listing
February 2019

Induction of mouse peritoneum mesenchymal stem cells into germ cell-like cells using follicular fluid and cumulus cells conditioned media.

Stem Cells Dev 2019 Feb 15. Epub 2019 Feb 15.

Royan Institute, 48499, Embryology, Tehran, Iran (the Islamic Republic of) ;

The peritoneum mesothelium lines body cavities and has the same origin as ovarian surface epithelium with probable existence of peritoneum mesenchymal stem cells (PMSCs). In the present research, PMSCs were isolated from peritoneum and differentiated into ovarian cell like cells using human follicular fluid (HFF) and human cumulus conditioned medium (HCCM). Anterior abdominal wall and intestinal peritoneum explants were used for cells isolation and cultured in DMEM. Read More

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http://dx.doi.org/10.1089/scd.2018.0149DOI Listing
February 2019

Beyond the Individual: Social and Cultural Influences on the Health-Seeking Behaviors of African American Men.

Am J Mens Health 2019 Jan-Feb;13(1):1557988319829953

1 FHI 360, Durham, NC, USA.

Morbidity and mortality rates are alarmingly high among African American men and are influenced by the health-seeking behaviors of this population. This study examined data from 40 focus groups with African American men in Durham, North Carolina, to better understand social and cultural influences on health-seeking behaviors. Data were analyzed using inductive thematic analysis. Read More

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http://dx.doi.org/10.1177/1557988319829953DOI Listing
February 2019

Study of validity, reliability in accordance with Turkey conditions in ego functions assessment scale.

Perspect Psychiatr Care 2019 Feb 14. Epub 2019 Feb 14.

Psychiatric Nursing Department, Health Sciences Faculty, Marmara University, İstanbul, Turkey.

Purpose: The aim of the study is to conduct a reliability and validity study of the Ego Function Assessment (EFA) scale.

Design And Methods: The study was conducted with a total of 426 participants, which included 213 patients with schizophrenia and a control group of 213 normal individuals. The Individual Information Form, EFA Scale, Wonderlic Personnel Test, Adjective Check List, and Symptom Check List were used for data collection. Read More

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http://dx.doi.org/10.1111/ppc.12357DOI Listing
February 2019

Elevated level of arsenic negatively influences nifH gene expression of isolated soil bacteria in culture condition as well as soil system.

Environ Geochem Health 2019 Feb 14. Epub 2019 Feb 14.

Department of Microbiology, University of Kalyani, Kalyani, West Bengal, 741235, India.

Comprehensive studies on the effect of arsenic (As) on free-living diazotrophs that play a crucial role in soil fertility by nitrogen fixation are still scanty. Here, we isolated three free-living bacteria from rice field with potential nitrogen-fixing ability and investigated the impact of As on their nifH gene expression and extracellular polysaccharide (EPS) production in culture condition and soil system. 16S rRNA sequence analysis showed that the isolated bacteria were affiliated to β-Proteobacteria, γ-Proteobacteria and Firmicutes. Read More

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http://dx.doi.org/10.1007/s10653-019-00261-2DOI Listing
February 2019

Recent Innovations in Diagnosis and Treatment of Pediatric Tuberculosis.

Curr Infect Dis Rep 2019 Feb 15;21(1). Epub 2019 Feb 15.

Medicine-Pediatric Residency Training Program, University of Colorado School of Medicine, Aurora, CO, USA.

Purpose Of Review: Tuberculosis is leading cause of global morbidity and mortality and a significant proportion of the burden of disease occurs in children. In the past 5 years, a number of innovations have improved the diagnosis and treatment for children with both latent tuberculosis infection and active disease.

Recent Findings: This review discusses three key areas of innovation. Read More

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http://link.springer.com/10.1007/s11908-019-0662-0
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http://dx.doi.org/10.1007/s11908-019-0662-0DOI Listing
February 2019
3 Reads

Regulatory effects of PRF and titanium surfaces on cellular adhesion, spread, and cytokine expressions of gingival keratinocytes.

Histochem Cell Biol 2019 Feb 14. Epub 2019 Feb 14.

Department of Periodontology, Institute of Dentistry, University of Turku, Lemminkäisenkatu 2, 20520, Turku, Finland.

Dental implant material has an impact on adhesion and spreading of oral mucosal cells on its surface. Platelet-rich fibrin (PRF), a second-generation platelet concentrate, can enhance cell proliferation and adhesion. The aim was to examine the regulatory effects of PRF and titanium surfaces on cellular adhesion, spread, and cytokine expressions of gingival keratinocytes. Read More

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http://link.springer.com/10.1007/s00418-019-01774-8
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http://dx.doi.org/10.1007/s00418-019-01774-8DOI Listing
February 2019
4 Reads

Ceftriaxone-resistant Salmonella Typhi Outbreak in Hyderabad City of Sindh, Pakistan: High Time for the Introduction of Typhoid Conjugate Vaccine.

Clin Infect Dis 2019 Feb;68(Supplement_1):S16-S21

Department of Pathology and Laboratory Medicine, Aga Khan University, Karachi.

Background: The Aga Khan University clinical microbiology laboratory identified an outbreak of ceftriaxone-resistant Salmonella Typhi in Hyderabad, Pakistan, through antimicrobial resistance surveillance. An outbreak investigation was carried out to identify the risk factors and institute control measures. Here we report the preliminary findings of this outbreak investigation, using data collected from 30 November 2016 to 28 March 2017. Read More

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http://dx.doi.org/10.1093/cid/ciy877DOI Listing
February 2019

Effect of the milk fat content and starter culture selection on proteolysis and antioxidant activity of probiotic yogurt.

Heliyon 2019 Feb 3;5(2):e01204. Epub 2019 Feb 3.

Department of Food Science and Technology, Faculty of Agriculture, Ferdowsi University of Mashhad, P. O. Box 91775-1163, Mashhad, Iran.

In this study, the effects of milk fat content (0%, 2% and 3.5%) and starter culture (autochthonous or commercial) on physicochemical properties, degree of proteolysis, antioxidant activity and viability of , within 21 days storage of probiotic yogurt at 5 ± 1 °C were investigated. Statistical analysis showed that the type of starter culture had a significant effect (P < 0. Read More

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http://dx.doi.org/10.1016/j.heliyon.2019.e01204DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360988PMC
February 2019

Effect of Chemotherapeutics and Tocopherols on MCF-7 Breast Adenocarcinoma and KGN Ovarian Carcinoma Cell Lines .

Biomed Res Int 2019 15;2019:6146972. Epub 2019 Jan 15.

Department of Medical Biotechnology, College of Medicine and Public Health, Flinders University, Adelaide, SA, 5052, Australia.

The combination of doxorubicin and cyclophosphamide commonly used to treat breast cancer can cause premature ovarian failure and infertility. -Tocopherol is a potent antioxidant whereas -tocopherol causes apoptosis in a variety of cancer models including breast cancer. We hypothesised that the combination of doxorubicin (Dox) and 4-hydroperoxycyclophosphamide (4-Cyc) would be more cytotoxic than each agent alone, and that -tocopherol would reduce and -tocopherol would augment the cytotoxicity of the combined chemotherapeutics. Read More

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http://dx.doi.org/10.1155/2019/6146972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350544PMC
January 2019

Lessons for the Health-care Practitioner from Buddhism.

Indian J Endocrinol Metab 2018 Nov-Dec;22(6):812-817

Department of Obstetrics, Bharti Hospital, Karnal, Haryana, India.

From its earliest days, Buddhism has been closely intertwined with the practice of medicine, both being concerned in their own way in the alleviation and prevention of human suffering. However, while the connection between Buddhism and healthcare has long been noted, there is scarce literature on how Buddhist philosophy can guide health-care practitioners in their professional as well as personal lives. In the sutras, we find analogies that describe the Buddha as a doctor, knowledge of Dharma as the treatment, and all lay people as patients. Read More

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http://dx.doi.org/10.4103/ijem.IJEM_286_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330872PMC
February 2019

Stress and the menopausal transition in Campeche, Mexico.

Womens Midlife Health 2018 18;4. Epub 2018 Jun 18.

4Department of Anthropology, University of Hawai'i at Hilo, Hilo, HI USA.

Background: Stress has been implicated as a factor in the presence and severity of symptoms during the menopausal transition. Our primary aim was to test the hypothesis that stress-sensitive biological measures and self-reported stress would be positively associated with a greater likelihood and intensity of hot flashes. Our secondary aim was to examine measures of stress in relation to the most often reported symptoms in Campeche, Mexico. Read More

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http://dx.doi.org/10.1186/s40695-018-0038-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298015PMC

Inhibition of cell proliferation, migration and colony formation of LS174T Cells by carbonic anhydrase inhibitor.

Afr Health Sci 2018 Dec;18(4):1303-1310

Department of Pharmaceutical Toxicology, Faculty of Pharmacy, İnönü University, Malatya, Turkey.

Background: Metastasis is the leading cause of cancer deaths. Migration of tumor cells is an important stage in metastasis. Therefore, recent studies have focused on clarifying migration and migration-dependent cell functions such as angiogenesis, wound healing, and invasion. Read More

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https://www.ajol.info/index.php/ahs/article/view/180343
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http://dx.doi.org/10.4314/ahs.v18i4.51DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354875PMC
December 2018
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Effects of gender, age and treatment duration on lipid profile and renal function indices in diabetic patients attending a teaching hospital in South-Western Nigeria.

Afr Health Sci 2018 Dec;18(4):900-908

Department of Biochemistry, School of Sciences, The Federal University of Technology, P.M.B. 704, Akure, Nigeria.

Background: Type 2 Diabetes Mellitus (T2DM) is associated with diabetic nephropathy and hyperlipidemia. Gender, age, medication adherence, lifestyle, culture and socioeconomic status could be sources of diversity in T2DM leading to differences in predisposition, development and clinical presentation.

Objectives: Therefore, this study aimed to investigate the influence of gender, age and treatment duration on kidney and lipid-related biochemical indices of T2DM patients attending Ekiti State University Teaching Hospital, Ado-Ekiti, Nigeria (EKSUTH). Read More

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http://dx.doi.org/10.4314/ahs.v18i4.8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354870PMC
December 2018

The Pathogenic Neisseria Use a Streamlined Set of Peptidoglycan Degradation Proteins for Peptidoglycan Remodeling, Recycling, and Toxic Fragment Release.

Front Microbiol 2019 31;10:73. Epub 2019 Jan 31.

Department of Medical Microbiology and Immunology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, United States.

and release peptidoglycan (PG) fragments from the cell as the bacteria grow. For these PG fragments are known to cause damage to human Fallopian tube tissue in organ culture that mimics the damage seen in patients with pelvic inflammatory disease. also releases pro-inflammatory PG fragments, but in smaller amounts than those from . Read More

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http://dx.doi.org/10.3389/fmicb.2019.00073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365954PMC
January 2019

Impact of oscillatory-cycloid vibration interventions on body composition, waist and hip circumference, and blood lipid profile in women aged over 65 years with hypercholesterolaemia.

Prz Menopauzalny 2018 Dec 31;17(4):161-167. Epub 2018 Dec 31.

Department of Biochemistry and Basics of Cosmetology, Faculty of Rehabilitation, University of Physical Education, Krakow, Poland.

Introduction: Vibration therapy interventions are an attractive alternative for people with contraindications to physical activity or manifesting kinesiophobia; they constitute an equivalent to physical activity.

Material And Methods: A group of female volunteers with hypercholesterolemia (LDL over 3 mmol/l) aged over 65 years were randomized into 2 subgroups: the study group (taking part in interventions on mattresses generating oscillatory-cycloid vibrations) and the control group (receiving interventions on placebo mattresses). All the subjects underwent two 30-minute interventions 5 times a week for the period of 21 days, in the prone position. Read More

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http://dx.doi.org/10.5114/pm.2018.81739DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372848PMC
December 2018

Hepatitis B Virus Infection of Normal Hepatic Stem/Progenitor Cells.

J Clin Exp Hepatol 2019 Jan-Feb;9(1):34-42. Epub 2018 Feb 16.

Section of Hepatology, Department of Medicine, University of Manitoba, Winnipeg, Canada.

Background/aims: Whether the hepatitis B virus (HBV) infects normal hepatic stem/progenitor cells (NSCs) and if so, whether such infections play a role in the pathogenesis of HBV-induced chronic liver disease (CLD) and/or hepatocellular carcinoma (HCC) remains to be determined. The objectives of this study were to determine whether HBV infects NSCs and whether such infections alter NSC activity in a manner likely to contribute to the development of CLD and/or HCC.

Methods: Liver biopsies from five hepatitis B surface antigen (HBsAg) positive patients were co-stained for HBcAg and HBx and the stem cell markers EpCAM, Oct-4 and Nanog. Read More

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http://dx.doi.org/10.1016/j.jceh.2018.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363946PMC
February 2018

Interferon-stimulated gene 15 modulates cell migration by interacting with Rac1 and contributes to lymph node metastasis of oral squamous cell carcinoma cells.

Oncogene 2019 Feb 14. Epub 2019 Feb 14.

National Institute of Cancer Research, National Health Research Institutes, Miaoli, Taiwan.

In an effort to understand the underlying mechanisms of lymph node metastasis in oral squamous cell carcinoma (OSCC), through in vivo selection, LN1-1 cells were previously established from OEC-M1 cells and showed enhanced lymphangiogenesis and lymphatic metastasis capabilities. In the current study, we use a stable isotope labeling with amino acids in cell culture (SILAC) and liquid chromatography-tandem mass spectrometry (LC-MS/MS)-based proteomic platform to compare LN1-1 to OEC-M1 cells. Interferon-stimulated gene 15 (ISG15) was found highly expressed in LN1-1 cells. Read More

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http://dx.doi.org/10.1038/s41388-019-0731-8DOI Listing
February 2019

Human trophoblast requires galectin-3 for cell migration and invasion.

Sci Rep 2019 Feb 14;9(1):2136. Epub 2019 Feb 14.

Laboratory for Biology of Reproduction, Institute for the Application of Nuclear Energy, University of Belgrade, Banatska 31b, 11080, Belgrade, Serbia.

Invasive extravillous cytotrophoblast of the human placenta expresses galectins-1, -3, and -8 in vivo and in vitro. This study aimed to investigate the potential role of galectin-3 in cell migration and invasion, using recombinant human galectin-3 (rhgalectin-3), small molecule galectin inhibitor I, and galectin-3 silencing. HTR-8/SVneo cell migration was stimulated by rhgalectin-3 and reduced by I, which could be neutralised by rhgalectin-3. Read More

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http://dx.doi.org/10.1038/s41598-018-38374-wDOI Listing
February 2019

Cartilage-Targeted IGF-1 Treatment to Promote Longitudinal Bone Growth.

Mol Ther 2019 Feb 1. Epub 2019 Feb 1.

Section on Growth and Development, National Institute of Child Health and Development, NIH, Bethesda, MD 20892, USA.

Recombinant human growth hormone (GH) is commonly used to treat short stature in children. However, GH treatment has limited efficacy, particularly in severe, non-GH-deficient conditions such as chondrodysplasias, and potential off-target effects. Because short stature results from decreased growth plate chondrogenesis, we developed a cartilage-targeting single-chain human antibody fragment (CaAb) aiming to deliver therapeutic molecules to the growth plate, thereby increasing treatment efficacy while minimizing adverse effects on other tissues. Read More

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http://dx.doi.org/10.1016/j.ymthe.2019.01.017DOI Listing
February 2019
6.227 Impact Factor

In vitro survival, growth, and maturation of sheep oocytes from secondary follicles cultured in serum-free conditions: impact of a constant or a sequential medium containing recombinant human FSH.

Domest Anim Endocrinol 2018 Dec 18. Epub 2018 Dec 18.

Nucleus of Biotechnology Applied to Ovarian Follicle Development, Federal University of São Francisco Valley, Petrolina, PE 56300-990, Brazil. Electronic address:

This study evaluated the in vitro development and maturation of ovine oocytes from secondary follicles cultured in serum-free medium containing fixed or sequential concentrations of recombinant human FSH (rhFSH). Follicles were cultured in α-MEM alone or with constant (500, 750, or 1,000 ng/mL) or sequential concentrations of rhFSH (seq. 1: day 6 = 500; day 12 = 750; day 18 = 1,000 ng/mL and seq. Read More

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http://dx.doi.org/10.1016/j.domaniend.2018.12.003DOI Listing
December 2018

The frequency of fungi isolated from the skin and hair of asymptomatic cats in rural area of Meshkin-shahr-Iran.

J Mycol Med 2019 Feb 11. Epub 2019 Feb 11.

Department of Medical Parasitology, Faculty of Veterinary, University of Tehran, 11369 Tehran, Iran.

Background: Dermatophytosis is a frequent cutaneous infection affecting the keratinized tissues of humans, pets and livestock. Animals can carry dermatophytic elements asymptomatically and are considered to play an important role in the epidemiology of the disease. As exposure to any infected lesion free animals, especially cats, may lead to the development of infection in humans. Read More

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http://dx.doi.org/10.1016/j.mycmed.2019.01.004DOI Listing
February 2019