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    New Advances in Focal Therapy for Early Stage Prostate Cancer.
    Expert Rev Anticancer Ther 2017 Jun 21. Epub 2017 Jun 21.
    b Division of Urology, Department of Surgery , Duke University Medical Center.
    Introduction: Prostate focal therapy offers men the opportunity to achieve oncological control while preserving sexual and urinary function. The prerequisites for successful focal therapy are to accurately identify, localize and completely ablate the clinically significant cancer(s) within the prostate. We aim to evaluate the evidence for current and upcoming technologies that could shape the future of prostate cancer focal therapy in the next five years. Read More

    5000 Meter Run Performance is not Enhanced 24 Hrs After an Intense Exercise Bout and Cold Water Immersion.
    J Sports Sci Med 2017 Jun 1;16(2):272-279. Epub 2017 Jun 1.
    Springfield College, Springfield, MA, USA.
    Cold water immersion (CWI) is used by endurance athletes to speed recovery between exercise bouts, but little evidence is available on the effects of CWI on subsequent endurance performance. The purpose of this study was to investigate the effects of CWI following an acute bout of interval training on 5000 m run performance 24 hrs after interval training, perceived muscle soreness (PMS), range of motion (ROM), thigh circumference (TC), and perceived exertion (RPE). Nine endurance-trained males completed 2 trials, each consisting of an interval training session of 8 repetitions of 1200 m at a running pace equal to 75% of VO2peak, either a control or CWI treatment, and a timed 5000 m run 24 hrs post interval training session. Read More

    Trends in Pap Test Practices and Results: An 11 Year Review of the Annual ACHA Pap Test and STI Survey.
    J Am Coll Health 2017 Jun 16. Epub 2017 Jun 16.
    c Department of Kinesiology , Health and Nutrition, One UTSA Circle, University of Texas at San Antonio , San Antonio , TX.
    Objective: To conduct a trend analysis of Pap test practices, Pap test results and related women's services and guidelines of college health centers.

    Participants: College health centers who participated in the annual ACHA Pap Test and STI Survey years 2004 to 2014 (n ranged from 127 to 181 depending on year).

    Methods: Descriptive analyses are presented with ANOVAs and chi-square tests calculated to examine trends over time. Read More

    Retinoblastoma.
    Indian J Pediatr 2017 Jun 16. Epub 2017 Jun 16.
    Ocular Oncology Service, National Retinoblastoma Foundation, Centre for Sight, Ashoka Capitol, Road No 2, Banjara Hills, Hyderabad, 500034, India.
    Retinoblastoma represents 3% of all childhood cancers, and is the most common intraocular malignancy of childhood. It is fatal, if untreated. White eye reflex, also known as leukocoria, is the commonest sign, followed by strabismus. Read More

    Cost-effectiveness of HPV-based cervical cancer screening in the public health system in Nicaragua.
    BMJ Open 2017 Jun 15;7(6):e015048. Epub 2017 Jun 15.
    Center for Health Decision Science, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
    Objectives: To evaluate the cost-effectiveness of human papillomavirus (HPV) DNA testing (versus Papanicolaou (Pap)-based screening) for cervical cancer screening in Nicaragua.

    Design: A previously developed Monte Carlo simulation model of the natural history of HPV infection and cervical cancer was calibrated to epidemiological data from Nicaragua. Cost data inputs were derived using a micro-costing approach in Carazo, Chontales and Chinandega departments; test performance data were from a demonstration project in Masaya department. Read More

    A case report of local treatment of inoperable squamous cell lung carcinoma with convex-probe endobronchial ultrasound-guided intratumoral injection of cisplatin in a patient with severe COPD.
    Medicine (Baltimore) 2017 Jun;96(24):e7070
    aDepartment of Pulmonary and Critical Care Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology bKey Laboratory of Respiratory Diseases, National Ministry of Health of the People's Republic of China and National Clinical Research Center for Respiratory Disease, Wuhan, China.
    Rationale: Endobronchial ultrasound as a powerful diagnostic technology can also be used to perform intratumoral chemotherapy for extraluminal tumor.

    Patient Concerns: A 69-year-old man with chronic obstructive pulmonary disease (COPD) presented with worsening dyspnea. A pulmonary function test showed severe airway obstruction and that forced expiratory volume in 1 s was 43% of the predicted value after a bronchodilator. Read More

    Recurrent Tumors Referred for Mohs Micrographic Surgery: A 12-Year Experience at a Single Academic Center.
    Dermatol Surg 2017 Jun 6. Epub 2017 Jun 6.
    *Department of Dermatology, Brown University, Providence, Rhode Island;†University of New England, College of Osteopathic Medicine, Biddeford, Maine.
    Background: Mohs micrographic surgery (MMS) is used for treatment of primary and recurrent tumors. Compared with primary tumors, recurrent tumors are often more aggressive.

    Objective: To understand differing characteristics between primary versus recurrent tumors treated by MMS. Read More

    Real versus sham proximal biofield therapy in the treatment of warts of the hands and feet in adults: study protocol for a randomized controlled trial (MAGNETIK study).
    Trials 2017 Jun 7;18(1):263. Epub 2017 Jun 7.
    Service de Dermatologie, Centre Hospitalier Régional Universitaire (CHU) de Caen, Avenue de la Côte de Nacre, CS 30001, F-14000, Caen, France.
    Background: Despite the lack of scientific studies on biofield therapies, they are widely acclaimed by patients. The mechanisms of action are not explained by current allopathic medical approaches. Warts are common and contagious viral lesions that may be refractory to standard dermatologic treatments such as cryotherapy, laser therapy, and keratolytic ointments. Read More

    A case report of the orbit, ocular association and the lung in granulomatosis with polyangiitis: A diagnostic challenge.
    Exp Ther Med 2017 Jun 28;13(6):3337-3340. Epub 2017 Apr 28.
    Department of Ophthalmology, The First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China.
    Granulomatosis with polyangiitis (GPA) is a systemic form of vasculitis that involves small to medium sized vessels and is associated with high morbidity and mortality. GPA presents a continuous and difficult clinical diagnostic concern, due to the rarity of the disease and the diversity of the manifestations. This case report discusses the unusual symptoms presented by a particular patient, discusses these manifestations and explains how the final diagnosis was identified as GPA. Read More

    Low-Dose-Rate Brachytherapy Versus Cryotherapy in Low- and Intermediate-Risk Prostate Cancer.
    Int J Radiat Oncol Biol Phys 2017 May 16;98(1):101-107. Epub 2017 Jan 16.
    Department of Radiation Oncology, Baylor Scott and White Memorial Hospital, Texas A&M University School of Medicine, Temple, Texas.
    Purpose: Cryotherapy and brachytherapy are definitive local treatment options for low- to intermediate-risk prostate cancer. There are both prospective and retrospective data for brachytherapy, but the use of cryotherapy has been limited primarily to single-institution retrospective studies. Currently, no published evidence has compared low-dose-rate brachytherapy versus cryotherapy. Read More

    Eales Disease.
    J Ayub Med Coll Abbottabad 2016 Oct-Dec;28(4):816-817
    Community Medicine Department, Khyber Medical College, Peshawar.
    Eales disease is an eponym after a British ophthalmologist Henry Eales. The aetiology behind Eales disease is ill-understood and stands controversial. Various systemic diseases associated with peripheral retinal revascularization and Retinal vasculitis could imitate the proliferative and inflammatory phases of Eales' disease, respectively. Read More

    Cryotherapy as a conservative treatment modality for gingival enlargement in a patient with Sturge-Weber Syndrome.
    Intractable Rare Dis Res 2017 May;6(2):145-1147
    Department of Pedodontics and Preventive Dentistry, Dr. R. Ahmad Dental College and Hospital, Sealdah, Kolkata, West Bengal, India.
    This case report describes a case of Sturge-Weber syndrome reported for unilateral gingival enlargement and bleeding from gingiva in maxillary left region. Initial treatment in the form of scaling and root planing was done but recurrence was observed after one year of follow up. Instead of performing conventional surgery, an alternative conservative treatment was planned in the form of cryotherapy with the help of closed nitrous oxide probe. Read More

    Cryotherapy for Barrett's Esophagus.
    Gastrointest Endosc Clin N Am 2017 Jul;27(3):503-513
    Division of Gastroenterology and Hepatology, The Johns Hopkins Hospital, Johns Hopkins Medical Institutions, Johns Hopkins University School of Medicine, 1800 Orleans Street, Blalock 407, Baltimore, MD 21287, USA. Electronic address:
    Cryotherapy or cryoablation involves the freezing of tissues to destroy unwanted tissue or to control bleeding. Endoscopic cryotherapy has been developed for gastrointestinal application by through-the-scope noncontact delivery of compressed carbon dioxide gas or liquid nitrogen (cryospray) or contact balloon cryoablation. The mechanism of cryotherapy ablative effects includes immediate injury as well as coagulation necrosis occurring over several hours and days, unlike heat-based thermal ablation. Read More

    Mechanical exposure of ophthalmic surgeons: a quantitative ergonomic evaluation of indirect ophthalmoscopy and slit-lamp biomicroscopy.
    Can J Ophthalmol 2017 Jun 18;52(3):302-307. Epub 2017 Jan 18.
    Department of Ophthalmology, Barts Health NHS Trust, London, England.
    Objective: Vitreoretinal (VR) surgeons have high rates of spinal pain. The aim of this study was to investigate if VR surgeons adopt more complex postures in indirect ophthalmoscopy procedures compared with procedures involving the slit-lamp or operating microscope.

    Methods: Postures of the neck, back, and overall spine were measured by inclinometers on 13 VR surgeons. Read More

    Variation in Locoregional Prostate Cancer Care and Treatment Trends at Commission on Cancer Designated Facilities: A National Cancer Data Base Analysis 2004 to 2013.
    Clin Genitourin Cancer 2017 Apr 26. Epub 2017 Apr 26.
    Center for Outcomes Research, Analytics and Evaluation, Vattikuti Urology Institute, Henry Ford Hospital, Detroit, MI. Electronic address:
    Background: Contemporary treatment trends for prostate cancer show increased rates of active surveillance. However, nationwide applicability of these reports is limited. Additionally, the effect of Commission on Cancer facility type on prostate cancer treatment patterns is unknown. Read More

    Microcystic Lymphatic Malformation Successfully Treated With Topical Rapamycin.
    Pediatrics 2017 May 12;139(5). Epub 2017 Apr 12.
    Department of Dermatology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
    Microcystic lymphatic malformations (MLM) are low-flow vascular malformations composed of multiple small cysts. MLM usually affect deep-lying structures, which makes their treatment even more difficult and complex. A novel and interesting treatment is rapamycin, a mammalian target of rapamycin inhibitor that when orally administrated has offered favorable results. Read More

    Lentigo maligna melanoma with a history of cosmetic treatment: Prevalence, surgical outcomes and considerations.
    Lasers Surg Med 2017 May 29. Epub 2017 May 29.
    Memorial Sloan Kettering Cancer Center, Dermatology Service, 16 E. 60th Street, 4th Floor Dermatology, New York, New York, 10022.
    Introduction: Lentigo maligna (LM) is melanoma in situ on sun-damaged skin and presents diagnostic challenges due to overlapping features with benign pigmented lesions. Cosmetic treatments may be inadvertently performed on LM. The aim of this study is to estimate the prevalence of LM with prior cosmetic treatment, and evaluate surgical outcomes. Read More

    Hemorrhagic angiodysplasia of the digestive tract: pathogenesis, diagnosis, and management.
    Gastrointest Endosc 2017 May 26. Epub 2017 May 26.
    Gastroenterology and Endoscopy division, Hôpital Européen Georges Pompidou, Assistance Publique - Hôpitaux de Paris, University Paris-Descartes Sorbonne-Paris Cité, Paris, France.
    Gastrointestinal angiodysplasia (GIA) is an acquired vascular superficial lesion, which presents typically as a bright red, irregular, round-shaped, slightly elevated lesion. GIAs are often seen in patients over 60 years of age and are mostly located in the colon (cecum and ascending).The cause and mechanisms of GIA have yet to be completely understood. Read More

    The use of foot pumps compression devices in the perioperative management of ankle fractures: Systematic review of the current literature.
    Foot (Edinb) 2017 Jun 10;31:61-66. Epub 2017 Mar 10.
    Department of Trauma and Orthopaedics, James Cook University Hospital, Marton Road, Middlesbrough, England TS4 3BW, United Kingdom.
    Background: Ankle fractures account for 9% of all fractures seen in the United Kingdom. 15,000 of these fractures undergo operative fixation each year. Soft tissue swelling impacts on timing of fixation due to fears of infection and wound dehiscence. Read More

    Cannula-associated Ocular Injuries during Cataract Surgery: A Preventable Intraoperative Complication?
    Middle East Afr J Ophthalmol 2017 Jan-Mar;24(1):54-56
    Department of Ophthalmology, The James Cook University Hospital, Middlesbrough TS4 3BW, UK.
    Although rare, inadvertently dislodged cannula can occur during cataract surgery. We report two cases of cannula-associated ocular injury during stromal hydration of the main corneal incision despite the use of Luer-lock syringes. Case 1 suffered from an initially occult intraocular injury which led to a delayed presentation of vitreous prolapsing into the anterior chamber, presumed posterior capsular rupture, vitreous hemorrhage, and multiple retinal tears, which required a three-port pars plana vitrectomy and cryotherapy. Read More

    Adjunctive Therapies for Bacterial Keratitis.
    Middle East Afr J Ophthalmol 2017 Jan-Mar;24(1):11-17
    Anterior Segment Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
    Bacterial keratitis is the most common type among all types of infectious keratitis. Currently, antibiotics are the main-stay of treatment. The objective of this systematic review is to review published clinical studies which discuss the adjunctive treatment of bacterial keratitis to guide clinical decision-making. Read More

    Local cryotherapy minimally impacts the metabolome and transcriptome of human skeletal muscle.
    Sci Rep 2017 May 25;7(1):2423. Epub 2017 May 25.
    Department of Orthopaedic Surgery, University of Michigan Medical School, Ann Arbor, MI, USA.
    Cryotherapy is commonly used in the treatment of skeletal muscle injuries. However, the data to support the use of cryotherapy is inconclusive, and the biochemical etiology of cryotherapy in human skeletal muscle remains largely unknown. We therefore sought to determine how a clinically-relevant dose of cryotherapy would impact the transcriptome and metabolome of skeletal muscle. Read More

    Treatment of disseminated superficial actinic porokeratosis with oral alitretinoin.
    J Eur Acad Dermatol Venereol 2017 May 22. Epub 2017 May 22.
    Department of Dermatology, College of Medicine, University of Hanyang, Seoul, Korea.
    Disseminated superficial actinic porokeratosis (DSAP), the most common type of porokeratosis, usually presents as large numbers of lesions on sun-exposed skin. Although several treatment options including corticosteroids, keratolytics, 5-fluorouracil, imiquimod, vitamin D3 analogues, cryotherapy, curettage, laser therapy and dermabrasion may be considered, there is no evidence-based standard treatment.(1-2) Patient 1 was a 26-year-old female who presented with a 2-year history of progressive scaly macules on both upper and lower extremities. Read More

    USE OF FEMORAL ARTERY ULTRASOUND DURING INTRAARTERIAL CHEMOTHERAPY FOR CHILDREN UNDER 10 KG WITH RETINOBLASTOMA.
    Retina 2017 May 23. Epub 2017 May 23.
    *Retina Consultants of Houston, Houston, Texas; †McGovern Medical School, The University of Texas Health Science Center, Houston, Texas; ‡Department of Neurological Surgery, McGovern Medical School, The University of Texas Health Science Center, Mischer Neuroscience Institute, Memorial Hermann Hospital, Houston, Texas; §Department of Anesthesiology, McGovern Medical School, The University of Texas Health Science Center, Memorial Hermann Hospital, Houston, Texas; ¶Department of Pediatrics, Division of Hematology-Oncology, McGovern Medical School, The University of Texas Health Science Center, Children's Memorial Hermann Hospital, Houston, Texas; and **Robert Cizik Eye Clinic, Ruiz Department of Ophthalmology and Visual Sciences, McGovern Medical School, The University of Texas Health Science Center, Houston, Texas.
    Purpose: To demonstrate the safety and efficacy of intraarterial chemotherapy (IAC) in small infants (<10 kg) with retinoblastoma.

    Methods: Retrospective, consecutive, observational case series of patients treated with IAC. Femoral arterial access was obtained using a micropuncture kit and ultrasound guidance, which enabled direct visualization. Read More

    Salvage focal cryosurgery may delay use of androgen deprivation therapy in cryotherapy and radiation recurrent prostate cancer patients.
    Int J Hyperthermia 2017 Mar 29:1-4. Epub 2017 Mar 29.
    a Department of Urology , Winthrop University Hospital , Garden City , NY , USA.
    Introduction: Salvage treatment options for recurrent unilateral prostate cancer (PCa) after primary radiation are limited and associated with severe complications and poor quality of life measures. Salvage focal cryotherapy (SFC) has shown success in biochemical recurrence (BCR) free survival. We aim to determine if SFC can delay use of androgen deprivation therapy (ADT) in recurrent PCa with low morbidity. Read More

    Dacryoendoscopy-guided transcanalicular intralesional interferon alpha 2b for canalicular squamous papillomas.
    Int Ophthalmol 2017 May 24. Epub 2017 May 24.
    Govindram Seksaria Institute of Dacryology, L.V. Prasad Eye Institute, Road No 2, Banjara Hills, Hyderabad, 500034, India.
    Canalicular papillomatosis is a rare disorder characterized by a mass lesion arising from the epithelium as a stalk from one of the canalicular walls. Traditionally, they have been treated with an open canaliculotomy and excision biopsy with or without additional cryotherapy. A patient with upper canalicular squamous papillomas treated with dacryoendoscopy-guided transcanalicular intralesional and topical interferon alpha 2b is presented, and the ineffectiveness of interferons in this case is discussed. Read More

    Promoting vascular repair in the retina: can stem/progenitor cells help?
    Eye Brain 2016 26;8:113-122. Epub 2016 May 26.
    Department of Ophthalmology.
    Since its first epidemic in the 1940s, retinopathy of prematurity (ROP) has been a challenging illness in neonatology. Higher than physiological oxygen levels impede the development of the immature retinal neuropil and vasculature. Current treatment regimens include cryotherapy, laser photocoagulation, and anti-VEGF agents. Read More

    Massive ear keloids: Natural history, evaluation of risk factors and recommendation for preventive measures - A retrospective case series.
    F1000Res 2016 13;5:2517. Epub 2016 Oct 13.
    Keloid Research Foundation, New York, NY, 10023, USA.
    Keloid disorder (KD) is an inherited wound healing ailment, frequently seen among Africans /African Americans and Asians.  Genetics of this disorder continues to be obscure and poorly understood.  Clinical manifestation of KD is quite variable and very diverse, spanning from individuals with one or very few small keloidal lesions, to those with numerous and very large lesions covering large portion of their skin. Read More

    Recent perspectives of management of breast cancer metastasis - an update.
    J BUON 2017 Mar-Apr;22(2):295-300
    Department of Oncological Surgery 2, Xuzhou City Central Hospital, the affiliated Hospital of the Southeast University Medical School (Xu zhou), the Tumor Research Institute of the Southeast University (Xu zhou), Xuzhou Jiangsu 221009, China.
    Breast cancer is the leading cause of cancer related deaths in women and one of the most common cancers globally. The major obstacle in the management of breast cancer, especially at advanced stages, is metastasis. Metastasis in the advanced stages of breast cancer could decrease survival to approximately 5 years. Read More

    Sequential pars plana vitrectomy and cataract extraction with intraocular lens implantation in patient with corneal inlay who developed retinal detachment followed by cataract.
    J Cataract Refract Surg 2017 Apr;43(4):570-571
    From the Department of Ophthalmology (Jabbur, Awwad, Bashshur), American University of Beirut Medical Center, and the Department of Ophthalmology (Jabbur), Clemenceau Medical Center, Beirut, Lebanon. Electronic address:
    Twenty-one months after successful small-aperture corneal inlay (Kamra) implantation simultaneous with myopic laser in situ keratomileusis, a patient presented with a superior rhegmatogenous macula-involving retinal detachment. Successful pars plana vitrectomy, transscleral cryotherapy, and gas tamponade were performed with the inlay in situ. Three months later, uneventful phacoemulsification and posterior chamber intraocular lens implantation were performed, also with the inlay in situ, for a visually significant cataract. Read More

    The effects of a treatment combination of anti-VEGF injections, laser coagulation and cryotherapy on patients with type 3 Coat's disease.
    BMC Ophthalmol 2017 May 22;17(1):76. Epub 2017 May 22.
    Beijing Ophthalmology and Visual Science Key Laboratory, Beijing Tongren Eye Center, Beijing Tongren Hospital,Capital Medical University, No. 1 Dongjiao Min Xiang, 100730, Beijing, People's Republic of China.
    Background: To examined the curative effect of vitreous injection with ranibizumab,laser coagulation and cryotherapy in treating stage 3 Coats' disease with exudative retinal detachment.

    Methods: Seventeen patients with stage 3 Coats' disease were enrolled in the study. All eyes were treated with vitreous injection of ranibizumab as initial treatment, and subsequent treatment depended on the absorption of subretinal fluid, Including cryotherapy and laser photocoagulation. Read More

    Acute Exacerbation of Interstitial Lung Disease After Cryobiopsy.
    J Bronchology Interv Pulmonol 2017 May 18. Epub 2017 May 18.
    *Division of Pulmonary, Allergy, Critical Care and Sleep Medicine †Department of Internal Medicine ‡Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN.
    Cryotherapy has been used in treatment of lung cancer for decades. The utility of cryotechnology in diagnosis of lung diseases is emerging and gaining popularity. Cryobiopsy (CB) of the lung, when compared with conventional transbronchial forceps lung biopsy, has proposed to have a higher diagnostic yield in interstitial lung disease by providing larger biopsy specimen and less crush artifact. Read More

    A case series of verrucae vulgares mimicking hyperkeratosis in individuals with diabetic foot ulcers.
    Diabet Med 2017 May 19. Epub 2017 May 19.
    Diabetes Division, Department of Medicine I, St. Josef-Hospital, Ruhr-University Bochum.
    Background: Diabetic foot ulcers are a common complication in the advanced stages of diabetes mellitus. Certain lesions may be refractory to usual treatments with prolonged healing. In these cases, differential diagnoses to classical ulcers should be considered. Read More

    Molluscum contagiosum: an update.
    Recent Pat Inflamm Allergy Drug Discov 2017 May 17. Epub 2017 May 17.
    Department of Paediatrics, The Chinese University of Hong Kong, Shatin. Hong Kong.
    Background: Molluscum contagiosum is a viral cutaneous infection in childhood that occurs worldwide. Physicians should familiarize themselves with this common condition.

    Objective: To review in depth the epidemiology, pathophysiology, clinical manifestations, complications and, in particular, treatment of molluscum contagiosum. Read More

    Large Bowel Obstruction following Endoscopic Spray Cryotherapy for Palliation of Rectal Cancer Bleeding.
    ACG Case Rep J 2017 10;4:e65. Epub 2017 May 10.
    Department of Gastroenterology, Cancer Treatment Centers of America at Midwestern Regional Medical Center, Zion, IL.
    We report a unique case of a 79-year-old woman with metastatic rectal cancer who developed bowel obstruction following endoscopic cryotherapy with liquid nitrogen for palliation of bleeding in the rectum. She developed abdominal distention and pain following the procedure. Computed tomography of the abdomen revealed a paraumbilical hernia containing a segment of transverse colon resulting in partial bowel obstruction. Read More

    Whole-Body Cryotherapy in Athletes: From Therapy to Stimulation. An Updated Review of the Literature.
    Front Physiol 2017 2;8:258. Epub 2017 May 2.
    Laboratory of Experimental Biochemistry and Molecular Biology, I.R.C.C.S. Istituto Ortopedico GaleazziMilan, Italy.
    Nowadays, whole-body cryotherapy is a medical physical treatment widely used in sports medicine. Recovery from injuries (e.g. Read More

    A Comparative Study of Liquid Nitrogen Cryotherapy as Monotherapy versus in Combination with Podophyllin in the Treatment of Condyloma Acuminata.
    J Clin Diagn Res 2017 Mar 1;11(3):WC01-WC05. Epub 2017 Mar 1.
    Junior Resident, Department of Dermatology, Government Medical College, Amritsar, Punjab. India.
    Introduction: Condyloma Acuminata (CA) is a common viral sexually transmitted disease. Although various treatment modalities are available for treating CA, but none of them can achieve 100% response rate. In a search for better response rate and less recurrence rate, the combination of cytotoxic agent Podophyllin with ablative liquid nitrogen cryotherapy was evaluated over cryotherapy alone. Read More

    Long-term Visual Acuity, Strabismus, and Nystagmus Outcomes Following Multimodality Treatment in Group D Retinoblastoma Eyes.
    Am J Ophthalmol 2017 May 10. Epub 2017 May 10.
    Moorfields Eye Hospital, London, United Kingdom; Retinoblastoma Service, Royal London Hospital, London, United Kingdom; National Institute for Health Research Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, United Kingdom.
    Purpose: To analyze the long-term visual acuity, strabismus, and nystagmus outcomes in Group D retinoblastoma following multimodality treatments in a national retinoblastoma referral center.

    Design: Retrospective interventional case series.

    Methods: A 13-year retrospective chart review of Group D eyes treated initially with intravenous chemotherapy (IVC) and followed up for at least 1 year from last treatment. Read More

    Vertebroplasty and interventional radiology procedures for bone metastases.
    Joint Bone Spine 2017 May 9. Epub 2017 May 9.
    Service de radiologie, hôpital Lariboisière, université Paris-Diderot, AP-HP, 2, rue Ambroise-Paré, 75010 Paris, France.
    Advances in cancer treatments have lengthened the survival of patients with bone metastases. Optimal control of the symptoms and prevention of the complications associated with bone metastases improve quality of life. Achieving these goals increasingly involves interventional radiology procedures. Read More

    Postoperative interventions to reduce inflammatory complications after third molar surgery: review of the current evidence.
    Aust Dent J 2017 May 12. Epub 2017 May 12.
    Maxillofacial Unit, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia.
    Inflammatory complications such as pain, swelling, trismus, infection and alveolar osteitis have an adverse affect on the quality of life of patients after third molar removal. This review presents the current evidence on postoperative strategies to reduce these complications. A literature search was performed to identify articles published in English between 2000 to 2016 using the following keywords: third molar(s), wisdom tooth/teeth, pain, swelling, trismus, infection, alveolar osteitis and dry socket. Read More

    Effect of whole-body cryotherapy on the rheological parameters of blood in older women with spondyloarthrosis.
    Clin Hemorheol Microcirc 2017 May 2. Epub 2017 May 2.
    Department of Clinical Rehabilitation, Faculty of Motor Rehabilitation, University of Physical Education, Krakow, Poland.
    Background: Cryotherapy is a physiotherapy method used to treat back pain in older persons.

    Objective: This study aims to evaluate the changes in the rheological parameters of blood in older women with spondyloarthrosis, who underwent whole-body cryotherapy.

    Methods: The experimental group comprised 69 older women with lumbar spondyloarthrosis, aged between 65 and 70 years. Read More

    Orf virus infection.
    Rev Med Virol 2017 May 8. Epub 2017 May 8.
    Dermatology Department, American University of Beirut Medical Center, Beirut, Lebanon.
    Orf virus (ORFV) is an important pathogen responsible for a highly contagious zoonotic viral infection that threatens those who handle sheep and goats. Orf virus is the prototype of the Parapoxvirus genus, and its resilience in the environment and ability to reinfect its host has contributed to the spread and maintenance of the infection in many species. In healthy humans, the disease usually resolves spontaneously within 3 to 6 weeks. Read More

    Effects of lymphatic drainage and cryotherapy on indirect markers of muscle damage.
    J Sports Med Phys Fitness 2017 May 5. Epub 2017 May 5.
    Institute of Training Science and Sport Informatics, German Sport University Cologne, Cologne, Germany.
    Background: Muscle enzymes are cleared from the extracellular space by the lymphatic system, while smaller proteins enter the bloodstream directly. We investigated if manual lymphatic drainage (MLD), local cryotherapy (CRY), and rest (RST) differently affect the time course of creatine kinase (CK, 84 kDa) and heart-type fatty acid binding protein (h-FABP, 15 kDa) in the blood.

    Design: Randomized controlled trial. Read More

    [Percutaneous lung thermo-ablation].
    Bull Cancer 2017 May 3;104(5):417-422. Epub 2017 May 3.
    Institut Gustave-Roussy, département d'imagerie, 114, rue Édouard-Vaillant, 94800 Villejuif, France.
    Percutaneous lung thermo-ablation has steadily been developed over the past 15years. Main indications are early stage non-small cell lung carcinoma (NSCLC) for non-surgical patients and slow evolving localized metastatic disease, either spontaneous or following a general treatment. Radiofrequency, being the most evaluated technique, offers a local control rate of about 80-90% for tumors <3 cm in diameter. Read More

    Small cryotherapy devices for the treatment of skin warts.
    J Dermatolog Treat 2017 May 16:1-6. Epub 2017 May 16.
    b Departments of Dermatology, Venereology, Allergology and Immunology , Dessau Medical Center, Theodore Fontane Medical University of Brandenburg , Dessau , Germany.
    Study Purpose: Effectiveness of cryotherapy on skin wart models.

    Materials And Methods: Two small cryotherapy devices, Wartner and Wortie, were administered for 10″-60″ on tomatoes and potatoes used as skin wart models. Frozen surface and depth were evaluated by standardized photography and computer analysis. Read More

    Efficacy of Nd:YAG laser therapy for the treatment of verrucae: a literature review.
    Lasers Med Sci 2017 Jul 2;32(5):1207-1211. Epub 2017 May 2.
    Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, 1475 NW 12th Ave., Suite 2175, Miami, FL, 33136, USA.
    Verrucae are benign epithelial proliferations, characteristically 1-20 mm in diameter, caused by human papilloma virus (HPV) infection occurring on the skin and mucosa (Photomed Laser Surg 33(6):338-42, 2015; Lasers Med Sci 29(3):1111-6, 2014). Prevalence of verrucae is 5-20% in children and young adults with peak incidence reported during teenage years (Lasers Med Sci 29(3):1111-6, 2014; J Am Acad Dermatol 22(4):547-66, 1990; J Korean Med Sci 24(5):889-93, 2009). Patients often express significant displeasure with quality of life due to this cosmetic insecurity, as well as functional problems and physical discomfort when they occur on palms of hands and soles of feet. Read More

    Cryotherapy With Dynamic Intermittent Compression Improves Recovery From Revision Total Knee Arthroplasty.
    J Arthroplasty 2017 Mar 31. Epub 2017 Mar 31.
    Département de chirurgie Orthopédique et Traumatologique, CHU Toulouse, Toulouse, France.
    Background: The goal of this study was to assess the efficacy of cryotherapy with dynamic intermittent compression (CDIC) in relieving postoperative pain, decreasing blood loss, and improving functional scores after revision total knee arthroplasty (rTKA).

    Methods: We conducted a prospective case-control study (level of evidence: I) to evaluate the efficacy of CDIC on postoperative bleeding, pain, and functional outcomes after rTKA. Forty-three cases were included at a single institution and divided in 2 groups: a control group without CDIC (n = 19) and an experimental group with CDIC (n = 24). Read More

    Intramuscular hemangiomas on the masseter muscle and orbicularis oris muscle: a report of two cases.
    J Korean Assoc Oral Maxillofac Surg 2017 Apr 25;43(2):125-133. Epub 2017 Apr 25.
    Department of Pathology, Inha University School of Medicine, Incheon, Korea.
    Intramuscular hemangioma (IMH) is a rare vascular disease involving skeletal muscle, comprising only 0.8% of hemangiomas. About 10% to 15% of IMHs occur in the head and neck region, mostly involving the masseter muscle. Read More

    Cervical Ectropion May Be a Cause of Desquamative Inflammatory Vaginitis.
    Sex Med 2017 Apr 28. Epub 2017 Apr 28.
    The Centers for Vulvovaginal Disorders, Washington, DC, and New York, NY, USA; George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
    Desquamative inflammatory vaginitis is a poorly understood chronic vaginitis with an unknown etiology. Symptoms of desquamative inflammatory vaginitis include copious yellowish discharge, vulvovaginal discomfort, and dyspareunia. Cervical ectropion, the presence of glandular columnar cells on the ectocervix, has not been reported as a cause of desquamative inflammatory vaginitis. Read More

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