2,070 results match your criteria Croatian medical journal[Journal]


Maintaining normality when serving a prison sentence in the digital society.

Croat Med J 2018 Dec;59(6):335-339

Eva Marie Toreld, Østfold University College, Department of Health and Social Studies, Fredrikstad, Norway,

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330768PMC
December 2018
1 Read

In vitro effects of hydrogen peroxide on rat uterine contraction before and during pregnancy.

Croat Med J 2018 Dec;59(6):327-334

Mohammed Alotaibi, Department of Physiology, College of Medicine, King Saud University, P.O. Box 2925, Riyadh 11461, KSA,

Aim: To assess the in vitro effect of hydrogen peroxide (H2O2) on uterine contractions in pregnant and non-pregnant rats.

Methods: The study was performed at the Department of Physiology, College of Medicine, King Saud University from December 2016 to October 2017. Intact uterine samples were obtained from non-pregnant (n=7-8) and term-pregnant (n=6-7) rats. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330773PMC
December 2018
1 Read

Comparison of Slovak reference values for anthropometric parameters in children and adolescents with international growth standards: implications for the assessment of overweight and obesity.

Croat Med J 2018 Dec;59(6):313-326

Valéria Regecová, Institute of Normal and Pathological Physiology, Center of Experimental Medicine, Slovak Academy of Sciences, Sienkiewiczova 1, 81371 Bratislava, Slovakia,

Aim: To compare the national reference percentile values for body height, weight, and body mass index (BMI) of children and adolescents in Slovakia with international standards and to analyze growth trends in this population.

Methods: The study was designed as a repeated cross-sectional survey. Two nationwide anthropometric surveys (NAS) performed in 2001 and 2011 assessed body weight, height, and BMI of 38 692 children aged 7 to 18 years. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330770PMC
December 2018
1 Read

Takotsubo cardiomyopathy after the first electroconvulsive therapy regardless of adjuvant beta-blocker use: a case report and literature review.

Croat Med J 2018 Dec;59(6):307-312

Sara Medved, Department of Psychiatry, Zagreb University Hospital Center, Kišpatićeva 12, 10 000 Zagreb, Croatia,

Takotsubo cardiomyopathy (TC) is a rare complication of electroconvulsive therapy (ECT), an effective and safe treatment for severe cases of depression and psychosis. There are reports on 16 patients who developed TC after ECT, and these were predominantly female patients treated with antidepressants for depressive disorder. We describe a case of a 40-year-old male patient, with a history of schizophrenia and heavy caffeine and nicotine use, treated for acute psychotic episode with haloperidol and clozapine. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330774PMC
December 2018
2 Reads

Liver damage indices as a tool for modifying methadone maintenance treatment: a cross-sectional study.

Croat Med J 2018 Dec;59(6):298-306

Željko Ključević, Public Health Institute of Split-Dalmatia County, Vukovarska 46, 21 000 Split, Croatia,

Aim: To assess the effect of liver damage on methadone metabolism in opiate addicts undergoing methadone maintenance treatment (MMT).

Methods: This cross-sectional study recruited 74 patients treated at the outpatient clinic of Public Health Institute of Split-Dalmatia County from 2013-2016. Concentrations of methadone and its main inactive metabolite were measured in participants' biological samples on regular check-ups. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330771PMC
December 2018
8 Reads

Impact of pharmacotherapeutic education on medication adherence and adverse outcomes in patients with type 2 diabetes mellitus: a prospective, randomized study.

Croat Med J 2018 Dec;59(6):290-297

Srećko Marušić, Medical Department, University Hospital Dubrava, Av. Gojka Šuška 6, 10000 Zagreb, Croatia,

Aim: To evaluate the impact of pharmacotherapeutic education on 30-day post-discharge medication adherence and adverse outcomes in patients with type 2 diabetes mellitus (T2DM).

Methods: The prospective, randomized, single-center study was conducted at the Medical Department of University Hospital Dubrava, Zagreb, between April and June 2018. One hundred and thirty adult patients with T2DM who were discharged to the community were randomly assigned to either the intervention or the control group. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330775PMC
December 2018
3 Reads

Editor ad interim - prospects and reality.

Authors:
Anton Glasnović

Croat Med J 2018 Dec;59(6):288-289

Anton Glasnović, Interim Editor-in-Chief, Croatian Medical Journal, Zagreb, Croatia,

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330772PMC
December 2018
1 Read

The Zagreb Collection of human brains: entering the virtual world.

Croat Med J 2018 Dec;59(6):283-287

Pero Hrabač, Department of Medical Statistics, Epidemiology, and Medical Informatics, "Andrija Štampar" School of Public Health, University of Zagreb School of Medicine, Zagreb, Croatia,

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330769PMC
December 2018
1 Read

Navigating Knowledge Landscapes in the digital society: a look back and visions for the future.

Croat Med J 2018 Oct;59(5):274-278

Srećko Gajović, University of Zagreb School of Medicine, Croatian Institute for Brain Research, Zagreb, Croatia,

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240819PMC
October 2018
2 Reads

The attitudes of international medical students toward educational methods and styles applied in a 6-year longitudinal course in fundamentals of medical skills in Croatia.

Croat Med J 2018 Oct;59(5):267-273

Ines Potočnjak, Vinogradska street 29, 10 000, Zagreb, Croatia,

Aim: To investigate international medical students' attitudes toward the impact of 6-year longitudinal course, Fundamentals of Medical Skills (FMS), at Medical Studies in English at the University of Zagreb on the development of their practical, clinical, and communication skills.

Methods: This cross-sectional study used a 23-item online survey to collect data from five generations of students attending the FMS course from January 31 to February 3, 2017. First-year students were not included. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240827PMC
October 2018
1 Read

Sport injuries in international masters rowers: a cross-sectional study.

Croat Med J 2018 Oct;59(5):258-266

Tomislav Smoljanović, Department of Orthopedic Surgery, University Hospital Center Zagreb, University of Zagreb School of Medicine, Šalata 6, 10000 Zagreb, Croatia,

Aim: To estimate the frequency and localization of acute (traumatic) and chronic (overuse) injuries in a population of masters rowers with respect to their age subgroups and assess the association between injury occurrence and different training modalities, rowing experience, previous competition level, and current rowing practice.

Methods: A cross-sectional study was conducted among 743 masters rowers who participated in the 34th International Federation of Rowing Associations (Fédération Internationale des Sociétés d'Aviron, FISA) World Rowing Masters Regatta held in Zagreb, September 2-9, 2007. A rowing-specific questionnaire was used, followed by an interview about the injuries sustained during the 12-month period before the competition. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240823PMC
October 2018
2 Reads

Femoral head wear and metallosis caused by damaged titanium porous coating after primary metal-on-polyethylene total hip arthroplasty: a case report.

Croat Med J 2018 Oct;59(5):253-257

Domagoj Delimar, Department of Orthopedic Surgery, University Hospital Centre Zagreb, Šalata 6-7, 10000 Zagreb, Croatia,

Excessive metal femoral head wear has been described only as revision surgery complication after primary ceramic-on-ceramic total hip arthroplasty (THA). Here, we present the first case of metal femoral head wear after primary metal-on-polyethylene THA. A 56-year-old woman was referred to our outpatient clinic 17 years after primary right-sided THA, experiencing pain and decreased right hip range of motion. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240820PMC
October 2018
14 Reads

Choline and N-acetyl aspartate levels in the dorsolateral prefrontal cortex at the beginning of the recovery phase as markers of increased risk for depressive episode recurrence under different duration of maintenance therapy and after it: a retrospective cohort study.

Croat Med J 2018 Oct;59(5):244-252

Pero Hrabač, Croatian Institute for Brain Research, University of Zagreb School of Medicine, 10000 Zagreb, Croatia,

Aim: To evaluate the relationship between the dynamics of proton magnetic resonance spectroscopy (1H-MRS) brain metabolite levels at the beginning of the recovery phase of the index depressive episode and the time to the recurrence of depression.

Methods: This retrospective cohort study analyzed the changes in N-acetyl aspartate (NAA), choline (Cho), and glutamate-glutamine in 48 patients with recurrent depression treated with maintenance antidepressant monotherapy at a stable dose. 1H-MRS was performed at the start of the recovery phase and 6 months later. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240822PMC
October 2018
9 Reads

Association of polymorphic variants in serotonin re-uptake transporter gene with Crohn's disease: a retrospective case-control study.

Croat Med J 2018 Oct;59(5):232-243

Frane Paić, Laboratory for Epigenetic and Molecular Medicine, Department of Biology and Medical Genetics, School of Medicine, University of Zagreb, Šalata 3, 10000 Zagreb, Croatia,

Aim: To analyze the distribution of SLC6A4 gene polymorphisms in Crohn's disease (CD) patients and their association with the disease.

Methods: We evaluated the presence/absence of promoter (5-HTTLPR, rs25531) and intron 2 (STin2 VNTR) polymorphic variants of SLC6A4 gene in a retrospective case-control study including 192 CD patients and 157 healthy controls (HC). Genotyping was performed by polymerase chain reaction. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240826PMC
October 2018
3 Reads
1.373 Impact Factor

Preponderance of microbial isolates among heart transplantation recipients requiring renal replacement therapy: a propensity score-adjusted analysis.

Croat Med J 2018 Oct;59(5):224-231

Hrvoje Gašparović, Department of Cardiac Surgery, University Hospital Center Zagreb, Kišpatićeva 12, 10000 Zagreb, Croatia,

Aim: To assess the association between renal replacement therapy (RRT) and post-transplant infection incidence.

Methods: This single-center retrospective cohort study included 158 patients who underwent heart transplantation (HTx) in our center from 2008 to 2016, survived beyond the first post-procedural day, and had available microbial data. The patients were dichotomized according to the need for periprocedural RRT. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240817PMC
October 2018
8 Reads
1.373 Impact Factor

Hypermethylation of Secreted Frizzled Related Protein 1 gene promoter in different astrocytoma grades.

Croat Med J 2018 10;59(5):213-223

Nives Pećina-Šlaus, Laboratory of Neurooncology, Croatian Institute for Brain Research, School of Medicine University of Zagreb, Šalata 12, 10000 Zagreb, Croatia,

Aim: To identify the involvement of Secreted Frizzled Related Protein 1 (SFRP1) promoter hypermethylation in different malignancy grades of astrocytoma and assess its association with beta-catenin, lymphoid-enhancer factor 1, and T-cell factor 1.

Methods: Twenty-six astrocytoma samples were collected from 2008-2015. Promoter hypermethylation was evaluated by methylation-specific polymerase-chain-reaction and protein expression by immunohistochemistry and stereological analysis. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240821PMC
October 2018
13 Reads

Transplantation of neural stem cells in the mouse model of ischemic brain stroke and expression of genes involved in programmed cell death.

Croat Med J 2018 Oct;59(5):203-212

Dinko Mitrečić, Laboratory for Stem Cells, Croatian Institute for Brain Research, University of Zagreb School of Medicine, Šalata 12, Zagreb, Croatia,

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240818PMC
October 2018
1 Read

Biphasic dendritic growth of dorsolateral prefrontal cortex associative neurons and early cognitive development.

Croat Med J 2018 Oct;59(5):189-202

Zdravko Petanjek, Department of Anatomy and Clinical Anatomy, University of Zagreb School of Medicine, Šalata 11, Zagreb, Croatia,

Aim: To analyze postnatal development and life-span changes of apical dendrite side branches (oblique dendrites) from associative layer IIIC magnopyramidal neurons in the human dorsolateral prefrontal cortex and to compare the findings with the previously established pattern of basal dendrite development.

Methods: We analyzed dendritic morphology from 352 rapid-Golgi impregnated neurons (10-18 neurons per subject) in Brodmann area 9 from the post-mortem tissue of 25 subjects ranging in age from 1 week to 91 years. Data were collected in the period between 1994 and 1996, and the analysis was performed between September 2017 and February 2018. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240825PMC
October 2018
10 Reads

The role of the University of Zagreb School of Medicine in the development of education, health care, and science in Croatia.

Authors:
Marijan Klarica

Croat Med J 2018 Oct;59(5):185-188

Marijan Klarica, Dean of the University of Zagreb School of Medicine, Zagreb, Croatia,

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240824PMC
October 2018
2 Reads

Digital mediators as key enablers of navigation toward health in knowledge landscapes.

Croat Med J 2018 08;59(4):178-182

Srećko Gajović, Croatian Institute for Brain Research, University of Zagreb School of Medicine, Zagreb, Croatia,

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139426PMC
August 2018
1 Read

Comparison of ego strength between aggressive and non-aggressive alcoholics: a cross-sectional study.

Croat Med J 2018 Aug;59(4):156-164

Zrnka Kovačić Petrović, University Hospital Vrapče, Bolnička 32, 10 000 Zagreb, Croatia,

Aim: To determine the differences between aggressive and non-aggressive alcoholics in sociodemographic and clinical characteristics and ego strength.

Methods: This cross-sectional study included 111 aggressive and 123 non-aggressive male alcoholics aged between 25 and 60 years who were admitted to the Department for Alcoholism, University Psychiatric Hospital Vrapče, Zagreb, Croatia, from January to December 2016. All participants met the diagnostic criteria for alcohol dependence according to the Croatian Mini International Neuropsychiatric Interview (MINI), 4th revised edition of Diagnostic and Statistical Manual of Mental Disorders, and the International Classification of Diseases. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139425PMC
August 2018
3 Reads

Prognostic value of lactates in relation to gas analysis and acid-base status in patients with pulmonary embolism.

Croat Med J 2018 Aug;59(4):149-155

Kristina Galić, Department of Internal Diseases, University of Mostar School of Medicine, Department of Lung Diseases, University Clinical Hospital Mostar, Bijeli Brijeg bb, 88000 Mostar, Bosnia and Herzegovina,

Aim: To assess the prognostic value of lactate level for mortality in patients with pulmonary embolism (PE) and Pulmonary Embolism Severity Index (PESI) I-III and its independence of gas-analysis parameters and acid-base status.

Methods: This prospective observational study was conducted at the University Clinical Hospital Mostar from 2013 to 2017. On the first day after PE diagnosis, 1. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139423PMC
August 2018
5 Reads

Association of levels of interleukin 17 and T-helper 17 count with symptom severity and etiology of chronic heart failure: a case-control study.

Croat Med J 2018 08;59(4):139-148

Ali Akbar Amirzargar, Department of Immunology, School ofMmedicine,Tehran University, of Medical Sciences, Poursina Avenue, Tehran, Iran, Iran,

Aim: To assess the association between the levels of interleukin 17 (IL-17) and T-helper 17 count and symptom severity and etiology of chronic heart failure.

Methods: This single-center prospective case-control study, conducted from December 1, 2015 to January 1, 2017 in Tehran Heart Center, evaluated gene expression of IL-17, relative count of (CD4+IL17+) Th17 cells and CD4+ helper T-cells in peripheral blood mononuclear cells of 42 patients with CHF and 42 matched controls. A multiple regression model assessed the predictors of peripheral IL-17 expression and Th17 count in patients with CHF. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139427PMC
August 2018
1 Read
1.373 Impact Factor

Knowledge-for-data trade at the interface between precision medicine and person-centered care.

Authors:
Srećko Gajović

Croat Med J 2018 06;59(3):132-135

Srećko Gajović, Croatian Institute for Brain Research, University of Zagreb School of Medicine, Zagreb, Croatia,

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045896PMC
June 2018
2 Reads

Adverse drug reaction reporting and development of pharmacovigilance systems in Bosnia and Herzegovina, Croatia, Serbia, and Montenegro: a retrospective pharmacoepidemiological study.

Croat Med J 2018 Jun;59(3):124-131

Una Glamočlija, School of Medicine, University of Mostar, Bijeli brijeg bb, 88 000 Mostar, Bosnia and Herzegovina,

Aim: To compare individual case safety reports (ICSR) rates and characteristics between Croatia, Serbia, Montenegro, and Bosnia and Herzegovina (B&H).

Methods: This retrospective pharmacoepidemiological study used the data from ICSR received by the Agency for Medicines and Medical Devices in B&H in 2011-2016. The number, characteristics, and sources of reports, suspected drugs, and patient characteristics were analyzed. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045893PMC
June 2018
2 Reads

Mortality patterns in Southern Adriatic islands of Croatia: a registry-based study.

Croat Med J 2018 Jun;59(3):118-123

Ozren Polašek, University of Split School of Medicine, Šoltanska 2, 21220 Split, Croatia,

Aim: To investigate the mortality patterns on the Southern Adriatic islands of Croatia and compare them with those in two, mainly coastal, mainland counties.

Methods: In this registry-based study we used the official mortality register data to analyze the mortality patterns on seven Croatian islands (Brač, Hvar, Korčula, Lastovo, Mljet, Šolta, and Vis) and Pelješac peninsula in the 1998-2013 period and calculated the average lifespan, life expectancy, and standardized mortality ratios (SMR). We compared the leading causes of death with those in the mainland population of two southernmost Croatian counties. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045898PMC
June 2018
13 Reads

Plasminogen activator inhibitor-1 activity and long-term outcome in patients with ST-elevation myocardial infarction treated with primary percutaneous coronary intervention: a prospective cohort study.

Croat Med J 2018 Jun;59(3):108-117

Marin Pavlov, Department of Cardiology, Sestre Milosrdnice University Hospital Center, Vinogradska cesta 29, 10000 Zagreb, Croatia,

Aim: To determine the relationship between plasminogen activator inhibitor-1 (PAI-1) activity rise during the first 24 hours of ST-elevation myocardial infarction (STEMI) treatment and death after 5 years.

Methods: From May 1, 2009 to March 23, 2010, 87 STEMI patients treated with primary percutaneous coronary intervention (PCI) at the Sestre Milosrdnice University Hospital Center were consecutively enrolled in prospective single-center cohort study. PAI-1 activity was determined on admission and 24 hours later. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045897PMC
June 2018
6 Reads

Microsatellite instability in metaplasia-dysplasia-adenocarcinoma sequence of Barrett esophagus: a retrospective study.

Croat Med J 2018 Jun;59(3):100-107

Pave Markoš, Division of Gastroenterology and Hepatology, University Hospital Center Zagreb, Kišpatićeva 12, 10000 Zagreb, Croatia,

Aim: To analyze the loss of mismatch repair (MMR) system protein expression in metaplasia-dysplasia-adenocarcinoma sequence of Barrett esophagus (BE).

Methods: This study retrospectively analyzed the data from 70 patients with pathohistological diagnosis of BE or esophageal adenocarcinoma (EAC) treated at the Clinical Department of Pathology and Cytology, University Hospital Center Zagreb, from January 2009 to January 2011. Patients were divided into three groups: BE without dysplasia (22 patients), BE with dysplasia (37 patients), and EAC (11 patients). Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045894PMC
June 2018
4 Reads

Gastroesophageal reflux disease, Barrett esophagus, and esophageal adenocarcinoma - where do we stand?

Croat Med J 2018 06;59(3):97-99

Ivana Mikolašević, Department of Gastroenterology, University Hospital Center Rijeka, University of Rijeka School of Medicine, Rijeka, Croatia,

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6045895PMC
June 2018
6 Reads

Child welfare services and social media - childhood, being and becoming in a digital society.

Croat Med J 2018 04;59(2):90-92

Siv-Britt Björktomta, Centre for Social Work (CESAR), Department of Sociology, Uppsala University, Uppsala, Sweden,

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941295PMC
April 2018
2 Reads

Influence of generic reference pricing on medicine cost in Slovenia: a retrospective study.

Croat Med J 2018 Apr;59(2):79-89

Mitja Kos, Chair of Social Pharmacy, University of Ljubljana, Faculty of Pharmacy, Aškerceva 7, 1000 Ljubljana, Slovenia,

Aim: To assess the impact of the generic reference pricing (GRP) system on the prices and cost of medicines in Slovenia approximately 8 years after its introduction in 2003 and before the implementation of the therapeutic reference pricing system.

Methods: A retrospective study of all medicines (N=789) included in the GRP system on January 31, 2012 was performed. Medicine prices and cost were analyzed between January 31, 2012 and December 31, 2013 after every update (N=11) of the maximum reimbursable price (MRP) and were compared to the price and cost on January 31, 2012 (index date). Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941292PMC
April 2018
2 Reads

Decreased tissue oxygenation in newborns with congenital heart defects: a case-control study.

Croat Med J 2018 Apr;59(2):71-78

Helena Lenasi, Institute of Physiology, Medical Faculty, University of Ljubljana, Zaloška 4, 1000 Ljubljana, Slovenia,

Aim: To compare regional tissue oxygenation (rSO2) in the brain, intestine, and kidney between newborns with and without congenital heart defects (CHD).

Methods: This observational case-control study was conducted at the Neonatal Department of Children's Hospital Ljubljana between December 2012 and April 2014. It included 35 newborns with CHD and 30 healthy age- and sex-matched controls. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941290PMC
April 2018
10 Reads

Prevalence of multiple sclerosis in Croatia: data from national and non-governmental organization registries.

Croat Med J 2018 Apr;59(2):65-70

Tomislav Benjak, Division for Public Health, Croatian Institute of Public Health, Rockefellerova ulica 7, 10000 Zagreb, Croatia,

Aim: To update the estimate of multiple sclerosis (MS) prevalence in Croatia using multiple epidemiological tools.

Methods: This level IV, epidemiological study gathered data from three national patient registries and one database of a non-governmental MS patients' organization. Data were extracted on all individuals who had undergone hospital MS treatment, consulted their primary health care providers about MS-related symptoms, been listed as having MS-related disability, or been members of the mentioned non-governmental organization in 2015. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941291PMC
April 2018
6 Reads

Activity of fosfomycin against nosocomial multiresistant bacterial pathogens from Croatia: a multicentric study.

Croat Med J 2018 Apr;59(2):56-64

Robert Likić, University Hospital Center Zagreb, Department of Internal Medicine, Unit of Clinical Pharmacology, Kispaticeva 12, 10000 Zagreb, Croatia,

Aim: To determine in vitro susceptibility of multiresistant bacterial isolates to fosfomycin.

Methods: In this prospective in vitro study (local non-random sample, level of evidence 3), 288 consecutively collected multiresistant bacterial isolates from seven medical centers in Croatia were tested from February 2014 until October 2016 for susceptibility to fosfomycin and other antibiotics according to Clinical and Laboratory Standards Institute methodology. Susceptibility to fosfomycin was determined by agar dilution method, while disc diffusion was performed for in vitro testing of other antibiotics. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941293PMC
April 2018
13 Reads

Suppression of the interleukin-1ß-induced inflammatory response of human Chang liver cells by acute and subacute exposure to alcohol: an in vitro study.

Croat Med J 2018 Apr;59(2):46-55

Borna Relja, Department of Trauma, Hand and Reconstructive Surgery, University Hospital Frankfurt, Goethe-University, 60590 Frankfurt, Germany,

Aim: To evaluate protective immunosuppressive dose and time-dependent effects of ethanol in an in vitro model of acute inflammation in human Chang liver cells.

Method: The study was performed in 2016 and 2017 in the research laboratory of the Department of Trauma, Hand and Reconstructive Surgery, the University Hospital of the Goethe-University Frankfurt. Chang liver cells were stimulated with either interleukin (IL)-1β or IL-6 and subsequently treated with low-dose ethanol (85 mmol/L) or high-dose ethanol (170 mmol/L) for one hour (acute exposure) or 72 hours (subacute exposure). Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941294PMC
April 2018
2 Reads

Science communication to the public.

Croat Med J 2018 04;59(2):43-45

Slobodan Vukičević, Laboratory of Mineralized Tissues, Scientific Center of Excellence for Reproductive and Regenerative Medicine, University of Zagreb School of Medicine, Zagreb, Croatia,

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941289PMC
April 2018
16 Reads

Re-thinking knowledge landscapes in the context of Grounded Aboriginal Theory and online health communication.

Croat Med J 2018 Feb;59(1):33-38

Kishan Kariippanon, University of Wollongong, School of Health and Society, Faculty of Social Science, Australia,

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833103PMC
February 2018
7 Reads

H-index in medicine is driven by original research.

Croat Med J 2018 Feb;59(1):25-32

Jan Nowak, Department of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, ul. Szpitalna 27/33, 60-572 Poznan, Poland,

Aim: To investigate the contribution of selected types of articles to h-indices of medical researchers.

Methods: We used the Web of Science to export the publication records of various members from 26 scientific medical societies (13 European, 13 North American) associated with 13 medical specialties. Those included were presidents (n=26), heads of randomly chosen committees (n=52), and randomly selected members of those committees (n=52). Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833098PMC
February 2018
5 Reads

Potential hot spot for de novo mutations in PTCH1 gene in Gorlin syndrome patients: a case report of twins from Croatia.

Croat Med J 2018 Feb;59(1):20-24

Vesna Musani, Division of Molecular Medicine, Ruđer Bošković Institute, Bijenička 54, 10000 Zagreb, Croatia,

We describe a case of twins with sporadic Gorlin syndrome. Both twins had common Gorlin syndrome features including calcification of the falx cerebri, multiple jaw keratocysts, and multiple basal cell carcinomas, but with different expressivity. One brother also had benign testicular mesothelioma. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833102PMC
February 2018
12 Reads

Effect of antiepileptic drug comedication on lamotrigine concentrations.

Croat Med J 2018 Feb;59(1):13-19

Mila Lovrić, Department of Laboratory Diagnostics, University Hospital Centre Zagreb, Kišpatićeva 12, 10 000 Zagreb,

Aim: To estimate the effect size of concomitant antiepileptic therapy on the concentrations of lamotrigine, a drug often prescribed in combination with other antiepileptic drugs (AED), which can act as enzyme inducers or inhibitors.

Methods: A total of 304 patients with epilepsy, aged 18-70 years, were divided into a lamotrigine monotherapy group and groups receiving lamotrigine with AEDs that act as enzyme inducers, enzyme inhibitors, or both. We compared lamotrigine monotherapy serum concentrations with those where lamotrigine was administered with a metabolic inhibitor valproate, metabolic inducers carbamazepine, oxcarbazepine, phenobarbital, phenytoin, or topiramate, and both an inducer and an inhibitor. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833099PMC
February 2018
21 Reads

Disease characteristics and causes of early and late death in a group of Croatian patients with systemic lupus erythematosus deceased over a 10-year period.

Croat Med J 2018 Feb;59(1):3-12

Ivan Padjen, Division of Clinical Immunology and Rheumatology, Department of Internal Medicine, University Hospital Center Zagreb and University of Zagreb School of Medicine, Kišpatićeva 12, 10000 Zagreb, Croatia,

Aim: To assess the causes of early death (ED) and late death (LD) in patients with systemic lupus erythematosus (SLE) and determine the features of deceased SLE patients followed-up in a single Croatian tertiary hospital center, because little if any data on causes of death (CODs) in SLE patients are available for Croatia.

Method: We identified SLE patients regularly followed-up at the Division of Clinical Immunology and Rheumatology, University Hospital Center Zagreb, who died from 2002 to 2011. Death was ascertained by matching our institutional records with the Croatian National Death Database. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833101PMC
February 2018
4 Reads

Explore! Dream! Discover!

Croat Med J 2018 Feb;59(1):1-2

Ana Marušić, University of Split School of Medicine, Split, Croatia,

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833100PMC
February 2018
5 Reads

Concepts and definitions of health and health-related values in the knowledge landscapes of the digital society.

Croat Med J 2017 Dec;58(6):431-435

Srećko Gajović, University of Zagreb School of Medicine, Croatian Institute for Brain Research, Zagreb, Croatia,

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778676PMC
December 2017
9 Reads

Severe acrocyanosis precipitated by cold agglutinin secondary to infection with Mycoplasma pneumoniae in a pediatric patient.

Croat Med J 2017 Dec;58(6):424-430

Bernadett Mosdósi, Department of Pediatrics, Clinical Center, University of Pécs, József Attila u. 7., H-7623 Pécs, Hungary,

This is the first report describing a severe form of cold agglutinin-induced acrocyanosis with cutaneous necrosis after Mycoplasma infection in a 9-year-old patient without any other severe symptoms and laboratory alterations. We also present the results of two non-invasive methods used to determine the viability of tissues, degree of tissue perfusion impairment, and the responsiveness of the microvasculature. Laser Doppler flowmetry and laser speckle contrast imaging, both suitable to measure tissue blood perfusion non-invasively, have been used in the diagnosis and follow-up of various peripheral vascular diseases. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778678PMC
December 2017
9 Reads

Severe bleeding complications and multiple kidney transplants in a patient with tuberous sclerosis complex caused by a novel TSC2 missense variant.

Croat Med J 2017 Dec;58(6):416-423

Zlatko Trobonjača, Department of Physiology and Immunology, University of Rijeka School of Medicine, Braće Branchetta 20, 51000 Rijeka, Croatia,

We presented an extremely severe case of tuberous sclerosis complex (TSC) in a female patient with recurring, life-threatening bleeding complications related to renal angiomyolipomas. Massive intratumoral hemorrhage required surgical removal of both angiomyolipomatous kidneys and kidney transplantation. During the follow-up period, the patient developed severe metrorrhagia that eventually led to hysterectomy and salpingo-oophorectomy. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778681PMC
December 2017
18 Reads

Comparison of RISK-PCI, GRACE, TIMI risk scores for prediction of major adverse cardiac events in patients with acute coronary syndrome.

Croat Med J 2017 Dec;58(6):406-415

Tamara Jakimov, Department of Cardiology, Clinical and Hospital Center "Bežanijska kosa", Autoput s/n, 11000 Belgrade, Serbia,

Aim: To compare the prognostic performance of three major risk scoring systems including global registry for acute coronary events (GRACE), thrombolysis in myocardial infarction (TIMI), and prediction of 30-day major adverse cardiovascular events after primary percutaneous coronary intervention (RISK-PCI).

Methods: This single-center retrospective study involved 200 patients with acute coronary syndrome (ACS) who underwent invasive diagnostic approach, ie, coronary angiography and myocardial revascularization if appropriate, in the period from January 2014 to July 2014. The GRACE, TIMI, and RISK-PCI risk scores were compared for their predictive ability. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778677PMC
December 2017
40 Reads

Anemia, hypoalbuminemia, and elevated troponin levels as risk factors for respiratory failure in patients with severe exacerbations of chronic obstructive pulmonary disease requiring invasive mechanical ventilation.

Croat Med J 2017 Dec;58(6):395-405

Marina Labor, Department of Pulmonology, University Hospital Center Osijek, Faculty of Medicine, J.J. Strossmayer University of Osijek, 31000 Osijek, Croatia,

Aim: To determine in-hospital and post-discharge mortality, readmission rates, and predictors of invasive mechanical ventilation (IMV) in patients treated at intensive care unit (ICU) due to acute exacerbations of chronic obstructive pulmonary disease (AECOPD).

Methods: A retrospective observational cohort study included all patients treated at a respiratory ICU for AECOPD during one year. A total of 62 patients (41 men) with mean age 68. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778679PMC
December 2017
13 Reads

Starling forces drive intracranial water exchange during normal and pathological states.

Croat Med J 2017 Dec;58(6):384-394

Andreas A. Linninger, Department of Bioengineering, Neurosurgery, University of Illinois at Chicago, 851 S Morgan St, Chicago, IL 60607, USA,

Aim: To quantify the exchange of water between cerebral compartments, specifically blood, tissue, perivascular pathways, and cerebrospinal fluid-filled spaces, on the basis of experimental data and to propose a dynamic global model of water flux through the entire brain to elucidate functionally relevant fluid exchange phenomena.

Methods: The mechanistic computer model to predict brain water shifts is discretized by cerebral compartments into nodes. Water and species flux is calculated between these nodes across a network of arcs driven by Hagen-Poiseuille flow (blood), Darcy flow (interstitial fluid transport), and Starling's Law (transmembrane fluid exchange). Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778682PMC
December 2017
7 Reads

The recent state of a hundred years old classic hypothesis of the cerebrospinal fluid physiology.

Croat Med J 2017 Dec;58(6):381-383

Darko Orešković, Ruđer Bošković Institute, Department of Molecular Biology, Zagreb, Croatia,

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778680PMC
December 2017
6 Reads