23,239 results match your criteria Croatian medical journal[Journal]


Persistent organic pollutants (POPs) in edible fish species from different fishing zones of Croatian Adriatic.

Mar Pollut Bull 2018 Dec 8;137:71-80. Epub 2018 Oct 8.

Innovation Center of the Faculty of Technology and Metallurgy, University of Belgrade, Karnegijeva 4, 11120 Belgrade, Serbia. Electronic address:

High-risk contaminants, OCPs and PCBs, were investigated in marine fish from the Adriatic Sea, from which retail fish in Croatia is commonly sourced. The pollutant levels in sardine, horse and chub mackerel, anchovy and round sardinella were analysed based on a two-year sampling and the joint use of generally accepted statistics and advanced clustering methods - self-organizing maps (SOM) and decision tree analysis (DT). Both the SOM and DT suggested fish mass and length rather than fat along with α-HCH, p,p'-DDT, PCB-74 and PCB-189 to cause variable pollutant uptake among species. Read More

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December 2018

Linear Predictors of Facial Rotation Pattern in Croatian Subjects with Skeletal Class III Malocclusion.

Acta Stomatol Croat 2018 Sep;52(3):227-237

Department of Orthodontics, School of Medicine, University of Rijeka, Croatia.

Objectives: The objective of this study was to determine whether the linear measures of the maxilla, mandible and cranial base were predictors of facial growth rotation in a Croatian population with Class III malocclusion by cephalometric radiographic methods.

Material And Methods: The examined sample consisted of pretreatment lateral cephalometric records of 201 (111 females and 90 males) untreated Class III patients of Caucasian Croatian ancestry from the Department of Orthodontics at Zagreb University. The measurements were divided into five categories for analysis: cranial base, skeletal maxillary and skeletal mandibular relationships, sagittal intermaxillary and vertical relationships. Read More

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September 2018
1 Read

Croatian National Data and Comparison with European Practice: Data from the Cardiac Resynchronization Therapy Survey II Multicenter Registry.

Cardiol Res Pract 2018 25;2018:3479846. Epub 2018 Oct 25.

Sestre Milosrdnice University Hospital Centre, Zagreb, Croatia.

Aims: The Cardiac Resynchronization Therapy (CRT) Survey II was conducted between October 2015 and December 2016 and included data from 11088 CRT implantations from 42 countries. The survey's aim was to report on current European CRT practice. The aim of this study was to compare the Croatian national CRT practice with the European data. Read More

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October 2018

[Professor dr. Zdravko Kučić (1910-1961), Promoter of the Hospital Service in Post-War Rijeka].

Authors:
Juraj Kučić

Acta Med Hist Adriat 2018 Dec;16(2):319-330

Gimnazijske stube 5, 51000 Rijeka, Hrvatska.

Dr Zdravko Kučić was born in Bakar on 11 April 1910. In1928 he finished the Gymnasium in Sušak and graduated from the School of Medicine, University of Belgrade in1934. After completing the internship in Zagreb, he worked at the General Public Hospital "King Alexander I" in Sušak as a secondary doctor of medicine and later as an assistant at the Internal Department. Read More

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December 2018

[Between Supervision and Functionality: The Architecture of the Institute for the Insane in Stenjevec].

Authors:
Vinko Drača

Acta Med Hist Adriat 2018 Dec;16(2):303-318

Odsjek za povijest, Filozofski Fakultet, Ivana Lučića 3, 10 000 Zagreb, Hrvatska.

This paper reviews the architecture of the Royal National Institute for the Insane in Stenjevec during its construction and the first years of its existence. Since the opening of the Institute in 1879 until the end of the World War I, there were numerous adaptations and extensions of the original capacities. The paper shows how these extensions reflected the existing paradigm of the institutional architecture in the second half of the 19th century. Read More

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December 2018

Hippocampal expression of cell-adhesion glycoprotein neuroplastin is altered in Alzheimer's disease.

J Cell Mol Med 2018 Nov 28. Epub 2018 Nov 28.

School of Medicine, Croatian Institute for Brain Research, University of Zagreb, Zagreb, Croatia.

Cell-adhesion glycoprotein neuroplastin (Np) is involved in the regulation of synaptic plasticity and balancing hippocampal excitatory/inhibitory inputs which aids in the process of associative memory formation and learning. Our recent findings show that neuroplastin expression in the adult human hippocampus is specifically associated with major hippocampal excitatory pathways and is related to neuronal calcium regulation. Here, we investigated the hippocampal expression of brain-specific neuroplastin isoform (Np65), its relationship with amyloid and tau pathology in Alzheimer's disease (AD), and potential involvement of neuroplastin in tissue response during the disease progression. Read More

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November 2018
2 Reads

Mitochondrial DNA diversity of the Roma from northeastern Bosnia, Bosnia and Herzegovina.

Homo 2018 Nov 7. Epub 2018 Nov 7.

Institute for Genetic Engineering and Biotechnology, University of Sarajevo, Sarajevo 73000, Bosnia and Herzegovina.

This study is the first report on the mtDNA diversity in the Roma population from Bosnia. The main aim of this study was to analyse the mtDNA diversity in the studied population, evaluate the genetic relations with other European Roma populations, and analyse the influences of the Roma gene flow on the mitochondrial profile of the Roma from northeastern Bosnia. MtDNA variability in the analysed population has been studied by means of hypervariable segment I and II (HVSI/II) of the control region sequencing and analysis of restriction fragment-length polymorphisms of the coding region. Read More

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November 2018

Different behaviour of DVL1, DVL2, DVL3 in astrocytoma malignancy grades and their association to TCF1 and LEF1 upregulation.

J Cell Mol Med 2018 Nov 23. Epub 2018 Nov 23.

Laboratory of Neuro-oncology, Croatian Institute for Brain Research, School of Medicine, University of Zagreb, Zagreb, Croatia.

Key regulators of the Wnt signalling, DVL1, DVL2 and DVL3, in astrocytomas of different malignancy grades were investigated. Markers for DVL1, DVL2 and DVL3 were used to detect microsatellite instability (MSI) and gross deletions (LOH), while immunohistochemistry and immunoreactivity score were used to determine the signal strengths of the three DVL proteins and transcription factors of the pathway, TCF1 and LEF1. Our findings demonstrated that MSI at all three DVL loci was constantly found across tumour grades with the highest number in grade II (P = 0. Read More

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November 2018
5 Reads

N-glycosylation patterns of plasma proteins and immunoglobulin G in chronic obstructive pulmonary disease.

J Transl Med 2018 Nov 21;16(1):323. Epub 2018 Nov 21.

Faculty of Pharmacy and Biochemistry, University of Zagreb, A. Kovačića 1, 10 000, Zagreb, Croatia.

Background: Chronic obstructive pulmonary disease (COPD) is a complex condition, whose diagnosis requires spirometric assessment. However, considering its heterogeneity, subjects with similar spirometric parameters do not necessarily have the same functional status. To overcome this limitation novel biomarkers for COPD have been investigated. Read More

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November 2018
2 Reads

Epidemiology of Prostate Cancer in Croatia - Situation and Perspectives.

Acta Clin Croat 2018 Oct;57(Suppl 1):27-34

Croatian National Cancer Registry, Croatian Institute of Public Health, Zagreb.

Prostate cancer represents a significant public health burden in Croatia, as well as in other developed countries. The aim of this paper was to present the current epidemiological situation in Croatia in comparison to other similar countries, using basic indicators such as incidence, mortality, prevalence and survival, and to discuss future possibilities in this field. The incidence of prostate cancer in Croatia has been rapidly increasing since the mid-nineties; recent data indicates that the trend is levelling off. Read More

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October 2018
2 Reads

History of Urology at the Sestre Milosrdnice University Hospital Center.

Acta Clin Croat 2018 Oct;57(Suppl 1):9-20

Department of Urology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia.

The history of Croatian urology clearly shows its affiliation to the medical and civilizational circle of the Western world. The Department of Urology at the Sestre milosrdnice University Hospital Center is the oldest urology institution in the Republic of Croatia. The Department was established in 1894, when the new Sestre milosrdnice Hospital was open in Vinogradska cesta in Zagreb. Read More

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October 2018
2 Reads

Plasma Fucosylated Glycans and C-Reactive Protein As Biomarkers of HNF1A-MODY in Young Adult-Onset Nonautoimmune Diabetes.

Diabetes Care 2018 Nov 19. Epub 2018 Nov 19.

Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia

Objective: Maturity-onset diabetes of the young (MODY) due to variants in is the commonest type of monogenic diabetes. Frequent misdiagnosis results in missed opportunity to use sulfonylureas as first-line treatment. A nongenetic biomarker could improve selection of subjects for genetic testing and increase diagnosis rates. Read More

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November 2018
2 Reads

Characterization of ADME genes variation in Roma and 20 populations worldwide.

PLoS One 2018 19;13(11):e0207671. Epub 2018 Nov 19.

Institute for Anthropological Research, Zagreb, Croatia.

The products of the polymorphic ADME genes are involved in Absorption, Distribution, Metabolism, and Excretion of drugs. The pharmacogenetic data have been studied extensively due to their clinical importance in the appropriate drug prescription, but such data from the isolated populations are rather scarce. We analyzed the distribution of 95 polymorphisms in 31 core ADME genes in 20 populations worldwide and in newly genotyped samples from the Roma (Gypsy) population living in Croatia. Read More

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November 2018

Impact of remote ischemic preconditioning preceding coronary artery bypass grafting on inducing neuroprotection.

J Thorac Cardiovasc Surg 2018 Oct 6. Epub 2018 Oct 6.

Department of Cardiac Surgery, University Hospital Center Zagreb, University of Zagreb, Zagreb, Croatia.

Background: Neurological complications after coronary artery bypass grafting (CABG) reduce quality of life, increase mortality, and inflate resource utilization. The risk of postoperative neurological complications parallels the increasing risk burden of the contemporary patient population. We evaluated the efficacy of remote ischemic preconditioning (RIPC) on inducing neuroprotection. Read More

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October 2018
1 Read

Prevalence and Correlation of Depressive Symptoms with Functional Scores, Therapy and Disease Activity among Croatian Patients with Rheumatoid Arthritis: A Preliminary Study.

Psychiatr Danub 2018 Dec;30(4):452-458

Clinic for Rheumatic Diseases and Rehabilitation, University Hospital Centre Zagreb, Zagreb, Croatia.

Background: Rheumatoid arthritis (RA) is a chronic, autoimmune and disabling disease that significantly affects the quality of life. Additionally, significant number of patients with RA suffer from depressive disorders, which are commonly underrecognised and undertreated. We aimed to estimate the prevalence of depressive symptoms in Croatian RA patients and to assess the relationship between them and clinical correlates. Read More

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December 2018
4 Reads

Expression of Nedd9 in Transbronchial Biopsies of Lung Adenocarcinoma.

Acta Clin Croat 2018 Jun;57(2):251-256

School of Medicine, University of Zagreb, Institute of Pathology and Zagreb University Hospital Centre, Clinical Department of Pathology and Cytology, Zagreb, Croatia.

Lung cancer as the major cause of cancer mortality worldwide includes several histologic subtypes evolving from numerous genetic and epigenetic changes emerging in alveolar, bronchiolar and bronchial epithelium. The majority of cases are diagnosed in advanced stage (i.e. Read More

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June 2018
2 Reads

Metabolic follow-up of a Croatian patient with gyrate atrophy and a new mutation in the gene: a case report.

Biochem Med (Zagreb) 2018 Oct;28(3):030801

Department of Pediatrics, University Hospital Center Zagreb, Zagreb, Croatia.

Gyrate atrophy (GA) of the choroid and retina is a rare autosomal recessive disorder that occurs due to deficiency of the mitochondrial enzyme ornithine aminotransferase (OAT). Hyperornithinemia causes degeneration of the retina with symptoms like myopia, reduced night vision and progressive vision loss. Our patient is a 10-year-old girl with impaired vision and strabismus. Read More

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October 2018
1 Read

Characterisation of Monovarietal Olive Oils Obtained from Croatian Drobnica and Buza during the Ripening Period.

Foods 2018 Nov 13;7(11). Epub 2018 Nov 13.

INA Refinery Urinj, HR-51000 Rijeka, Croatia.

The aim of this study was the monitoring of the chemical composition of olive oil at different ripening stages to determine the appropriate harvesting time during any given crop season in the northern Adriatic region. For this purpose, from September to November, two Croatian olive cultivars (Drobnica and Buza) were taken from two different olive orchards and for the respective olive oils, prepared on a laboratory scale, the major saponifiable, unsaponifiable and phenolic compounds were determined. Based on the chemical analyses performed, the optimal harvesting time has been set in October for both cultivars. Read More

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November 2018

The effects of monthly air temperature and rainfall variations on the reproductive performance and lambing distribution of the Jezersko-Solčava sheep.

Int J Biometeorol 2018 Nov 12. Epub 2018 Nov 12.

Faculty of Veterinary Medicine University of Zagreb, 10000, Zagreb, Croatia.

The aim of this study was to investigate the effects of monthly air temperature and rainfall variations on the reproductive performance and lambing distribution of the Jezersko-Solčava breed in northwestern Croatia during 7 years period from 2010 until 2016. At 11 medium-scale sheep farms, the sheep were kept on a pasture in a semi-intensive environment with access to the stables. The anomalies of rainfall observed on a monthly basis during monitoring were statistically significant. Read More

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November 2018
1 Read

Distribution of hepatitis C virus genotypes and subtypes in Croatia: 2008-2015.

Cent Eur J Public Health 2018 Sep;26(3):159-163

University Hospital for Infectious Diseases, Zagreb, Croatia.

Objective: Hepatitis C virus (HCV) genotyping is an important part of pre-treatment diagnostic algorithms as it guides the choice of therapeutic regimens. The aim of this study was to analyse the distribution of HCV genotypes in patients with chronic hepatitis C from Croatia in the period 2008-2015.

Methods: The study enrolled 3,655 anti-HCV positive patients with available results of HCV genotyping from the three largest national HCV genotyping laboratories. Read More

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September 2018

Neuroimaging research in posttraumatic stress disorder - Focus on amygdala, hippocampus and prefrontal cortex.

Prog Neuropsychopharmacol Biol Psychiatry 2018 Nov 9;90:37-42. Epub 2018 Nov 9.

Croatian Institute for Brain Research, School of Medicine, University of Zagreb, Croatia; University Hospital Centre, 'Sestre milosrdnice', Zagreb, Croatia. Electronic address:

Neuroimaging research reflects the complexity of post-traumatic stress disorder and shares some common difficulties of post-traumatic stress disorder research, such as the different classifications of the disorder over time, changes in diagnostic criteria, and extensive comorbidities, as well as precisely delineated and prevailing genetic and environmental determinants in the development of the disorder and its clinical manifestations. Synthesis of neuroimaging findings in an effort to clarify causes, clinical manifestations, and consequences of the disorder is complicated by a variety of applied technical approaches in different brain regions, differences in symptom dimensions in a study population, and typically small sample sizes, with the interplay of all of these consequently bringing about divergent results. Furthermore, combinations of the aforementioned issues serve to weaken any comprehensive meta-analytic approach. Read More

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November 2018
3 Reads

Hydrogen bonding between ethynyl aromates and triethylamine: IR spectroscopic and computational study.

Spectrochim Acta A Mol Biomol Spectrosc 2019 Feb 2;209:288-294. Epub 2018 Nov 2.

Department of Science and Environment, Roskilde University, Universitetsvej 1, P.O. Box 260, DK-4000 Roskilde, Denmark. Electronic address:

Ethynylpyridines (EPs) and ethynylbenzene (EB) are multifunctional systems able to participate in hydrogen-bonded complexes as both donors and acceptors of the H-atom. Their structures and stabilities are mainly a function of the hydrogen-bonding properties of the partner in the complex and the surroundings in which the complexation occurs. In this paper, IR spectroscopy and quantum chemical calculations are employed to characterize hydrogen-bonded complexes of 2- and 3-EP and EB with triethylamine (TEA) in tetrachloroethene (CCl) solution. Read More

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February 2019

A Survey of Current Prophylactic Treatment for Ophthalmia Neonatorum in Croatia and a Review of International Preventive Practices.

Med Sci Monit 2018 Nov 10;24:8042-8047. Epub 2018 Nov 10.

Psychiatric Hospital "Sveti Ivan", Zagreb, Croatia.

BACKGROUND Ophthalmia neonatorum, or neonatal conjunctivitis, is an acute infection that occurs within the first 28 days of life. This aim of this survey was to evaluate the current methods of preventive treatment for ophthalmia neonatorum in maternity hospitals in Croatia. MATERIAL AND METHODS The annual hospital birth rate in Croatia is approximately 40,000. Read More

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November 2018
3 Reads

Global and regional estimates of the morbidity due to type I diabetes among children aged 0-4 years: a systematic review and analysis.

J Glob Health 2018 Dec;8(2):021101

Centre for Global Health Research and World Health Organization's Collaborating Centre for Population Health, Research and Training, The Usher Institute, University of Edinburgh, UK.

Background: Epidemiology of type 1 diabetes mellitus (T1DM) among children aged 0-4 years globally is not well understood. We aim to assess the incidence of T1DM in low- and middle-income countries (LMIC) by conducting a systematic review of previous reports. We also aim to address possible contribution to child mortality and to identify any temporal trends. Read More

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December 2018
3 Reads

Severe refractory bilateral shoulder dystocia released with digital hooking (Bourgeois-Siegemundin) manoeuvre.

Authors:
Dubravko Habek

J Obstet Gynaecol 2018 Nov 8. Epub 2018 Nov 8.

a University Department of Obstetrics and Gynecology, Sveti Duh University Hospital, Croatian Catholic University , Zagreb , Croatia.

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November 2018

Drought-induced shift in tree response to climate in floodplain forests of Southeastern Europe.

Sci Rep 2018 Nov 7;8(1):16495. Epub 2018 Nov 7.

University of Zagreb, Faculty of Forestry, Department of Forest Ecology and Silviculture, Svetošimunska 25, 10002, Zagreb, Croatia.

Floodplain forests are the most rapidly disappearing ecosystem in the world, especially in temperate regions of Europe where anthropogenic influence has been pronounced throughout history. Research on primeval forests is crucial to further our understanding of their natural dynamics and interaction with climate but is limited by the lack of such preserved forests. The aim of this study was to investigate how a primeval floodplain forest in Southeastern Europe has responded to climate variability during the last 250 years through comparison of tree growth and climate, canopy disturbance and recruitment dynamic of two dominant tree species with different tolerances to flooding/drought. Read More

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November 2018
1 Read

Navigating Knowledge Landscapes in the digital society: a look back and visions for the future.

Croat Med J 2018 Oct;59(5):274-278

Srećko Gajović, University of Zagreb School of Medicine, Croatian Institute for Brain Research, Zagreb, Croatia,

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October 2018

Choline and N-acetyl aspartate levels in the dorsolateral prefrontal cortex at the beginning of the recovery phase as markers of increased risk for depressive episode recurrence under different duration of maintenance therapy and after it: a retrospective cohort study.

Croat Med J 2018 Oct;59(5):244-252

Pero Hrabač, Croatian Institute for Brain Research, University of Zagreb School of Medicine, 10000 Zagreb, Croatia,

Aim: To evaluate the relationship between the dynamics of proton magnetic resonance spectroscopy (1H-MRS) brain metabolite levels at the beginning of the recovery phase of the index depressive episode and the time to the recurrence of depression.

Methods: This retrospective cohort study analyzed the changes in N-acetyl aspartate (NAA), choline (Cho), and glutamate-glutamine in 48 patients with recurrent depression treated with maintenance antidepressant monotherapy at a stable dose. 1H-MRS was performed at the start of the recovery phase and 6 months later. Read More

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October 2018
5 Reads

Hypermethylation of Secreted Frizzled Related Protein 1 gene promoter in different astrocytoma grades.

Croat Med J 2018 10;59(5):213-223

Nives Pećina-Šlaus, Laboratory of Neurooncology, Croatian Institute for Brain Research, School of Medicine University of Zagreb, Šalata 12, 10000 Zagreb, Croatia,

Aim: To identify the involvement of Secreted Frizzled Related Protein 1 (SFRP1) promoter hypermethylation in different malignancy grades of astrocytoma and assess its association with beta-catenin, lymphoid-enhancer factor 1, and T-cell factor 1.

Methods: Twenty-six astrocytoma samples were collected from 2008-2015. Promoter hypermethylation was evaluated by methylation-specific polymerase-chain-reaction and protein expression by immunohistochemistry and stereological analysis. Read More

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October 2018
9 Reads

Transplantation of neural stem cells in the mouse model of ischemic brain stroke and expression of genes involved in programmed cell death.

Croat Med J 2018 Oct;59(5):203-212

Dinko Mitrečić, Laboratory for Stem Cells, Croatian Institute for Brain Research, University of Zagreb School of Medicine, Šalata 12, Zagreb, Croatia,

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October 2018

NEW IMPACT FACTOR FOR ACTA DERMATOVENEROLOGICA CROATICA.

Acta Dermatovenerol Croat 2018 Oct;26(3):197-198

June brought us good news: based on the new impact factors for 2017 published by Clarivate analytics (previously Thompson-Reuters), Acta Dermatovenerologica Croatica (ADC) has reached one of the milestones - an impact factor (IF) of 1.054! After entering Excerpta Medica in 1994, Index Medicus / Medline in 2001, and the Science Citation Index Expanded in 2007, we tried our best to improve the visibility and presence of our Journal and to increase its impact factor. From 2009 to 2015, the IF of ADC was between 0. Read More

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October 2018
1 Read

Biochemical and reproductive effects of red mud to earthworm Eisenia fetida.

Ecotoxicol Environ Saf 2019 Jan 31;168:279-286. Epub 2018 Oct 31.

University of Osijek, Department of Biology, Cara Hadrijana 8A, Osijek, Croatia. Electronic address:

Red mud (RM) is the main waste of alumina production whose disposal poses a problem. The research of various possible effects of red mud on soil organisms has been scarce. We have exposed earthworms (Eisenia fetida) to red mud: artificial soil mixtures. Read More

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January 2019
4 Reads

Fas receptor induces apoptosis of synovial bone and cartilage progenitor populations and promotes bone loss in antigen-induced arthritis.

FASEB J 2018 Nov 1:fj201801426R. Epub 2018 Nov 1.

Laboratory for Molecular Immunology, Croatian Institute for Brain Research, University of Zagreb School of Medicine, Zagreb, Croatia.

Rheumatoid arthritis (RA) is inflammatory joint disease that eventually leads to permanent bone and cartilage destruction. Fas has already been established as the regulator of inflammation in RA, but its role in bone formation under arthritic conditions is not completely defined. The aim of this study was to assess the effect of Fas inactivation on the bone damage during murine antigen-induced arthritis. Read More

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November 2018
7 Reads

Seroprevalence of vector-borne pathogens in dogs from Croatia.

Parasitol Res 2018 Oct 31. Epub 2018 Oct 31.

Department for Bacteriology and Parasitology, Croatian Veterinary Institute, Zagreb, Savska cesta 143, 10000, Zagreb, Croatia.

Canine vector-borne pathogens (VBPs) are a group of globally distributed and rapidly spreading microorganisms transmitted by arthropods. In the present survey, we investigated Anaplasma spp., Ehrlichia canis, Dirofilaria immitis and Borrelia burgdorferi sensu lato seroprevalence between three groups of dogs (asymptomatic, suspected and deceased) from continental and coastal regions of Croatia with the commercial point-of-care SNAP®4Dx®Plus for VBPs. Read More

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October 2018
1 Read

Reporting quality of European and Croatian health practice guidelines according to the RIGHT reporting checklist.

Implement Sci 2018 Oct 29;13(1):135. Epub 2018 Oct 29.

Department of Research in Biomedicine and Health, University of Split School of Medicine, Split, Croatia.

Background: Health practice guidelines (HPGs) are important tools for the translation of evidence into practice. Reporting Items for Practice Guidelines in HealThcare (RIGHT) checklist provides guidance on reporting health practice guidelines (HPGs). We assessed the reporting completeness and quality of a set of national (Croatian) and relevant transnational (European) HPGs. Read More

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October 2018
1 Read

Attitudes and beliefs related to childhood vaccinations among parents of 6 years old children in Zagreb, Croatia.

Vaccine 2018 Nov 23;36(49):7530-7535. Epub 2018 Oct 23.

School and Adolescent Medicine Service, Youth Service, Andrija Štampar Teaching Institute of Public Health Zagreb, Mirogojska 16, 10 000 Zagreb, Croatia.

The Croatian Immunization Programme is a mandatory prevention programme in which vaccines are offered free of charge and little is known about parental vaccine-related beliefs and attitudes. We aimed to describe beliefs and attitudes towards childhood vaccination of parents in Zagreb, estimate the proportion of parents with positive attitudes towards vaccination, and to identify the possible predictors of positive attitudes. Using a self-administered questionnaire, we performed a cluster sampling survey among parents of 6-years-old children in Zagreb. Read More

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November 2018
3 Reads

Evolution of MHC class II SLA-DRB1 locus in the Croatian wild boar (Sus scrofa) implies duplication and weak signals of positive selection.

Anim Genet 2018 Oct 24. Epub 2018 Oct 24.

Department of Biology, Faculty of Science, University of Zagreb, Rooseveltov trg 6, 10000, Zagreb, Croatia.

The wild boar is an ancestor of the domestic pig and an important game species with the widest geographical range of all ungulates. Although a large amount of data are available on major histocompatibility complex (MHC) variability in domestic pigs, only a few studies have been performed on wild boars. Due to their crucial role in appropriate immune responses and extreme polymorphism, MHC genes represent some of the best candidates for studying the processes of adaptive evolution. Read More

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October 2018
8 Reads

Attitudes and Knowledge About Plagiarism Among University Students: Cross-Sectional Survey at the University of Split, Croatia.

Sci Eng Ethics 2018 Oct 24. Epub 2018 Oct 24.

Department of Research in Biomedicine and Health, University of Split School of Medicine, Šoltanska 2, 21000, Split, Croatia.

Plagiarism is one of the most severe academic integrity issues. This study examined students' knowledge of and attitudes towards plagiarism, tested their ability to recognize plagiarism, and explored the association of study levels and attendance in courses dealing with referencing rules and plagiarism with students' attitudes and knowledge. A cross-sectional online survey was conducted at the University of Split, comprising the students of all schools and study levels (n = 388). Read More

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October 2018

Development and validation of a rapid method for genotyping three P-selectin gene polymorphisms based on high resolution melting analysis.

J Clin Lab Anal 2018 Oct 23:e22698. Epub 2018 Oct 23.

Faculty of Pharmacy and Biochemistry, Department of Medical Biochemistry and Haematology, University of Zagreb, Zagreb, Croatia.

Background: High resolution melting (HRM) analysis is one of the newer, reliable, and sensitive genotyping techniques, which offers considerable time and cost savings. P-selectin is an adhesion molecule that has a role in the initial phases of leukocyte adhesion to stimulated platelets and endothelial cells in inflammation. Multiple polymorphisms in P-selectin gene (SELP) that affect the protein sequence have been described. Read More

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October 2018
5 Reads

Limited Genetic Structure of Gypsy Moth Populations Reflecting a Recent History in Europe.

Insects 2018 Oct 18;9(4). Epub 2018 Oct 18.

Forest Research Institute, Hellenic Agricultural Organization Demeter, Vasilika, 57006 Thessaloniki, Greece.

The gypsy moth, , a prominent polyphagous species native to Eurasia, causes severe impacts in deciduous forests during irregular periodical outbreaks. This study aimed to describe the genetic structure and diversity among European gypsy moth populations. Analysis of about 500 individuals using a partial region of the mitochondrial COI gene, was characterized by low genetic diversity, limited population structure, and strong evidence that all extant haplogroups arose via a single Holocene population expansion event. Read More

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October 2018

Emergence of superconductivity in the cuprates via a universal percolation process.

Nat Commun 2018 10 18;9(1):4327. Epub 2018 Oct 18.

School of Physics and Astronomy, University of Minnesota, Minneapolis, MN, 55455, USA.

A pivotal step toward understanding unconventional superconductors would be to decipher how superconductivity emerges from the unusual normal state. In the cuprates, traces of superconducting pairing appear above the macroscopic transition temperature T, yet extensive investigation has led to disparate conclusions. The main difficulty has been to separate superconducting contributions from complex normal-state behaviour. Read More

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October 2018
1 Read

Association of MAPT haplotype-tagging polymorphisms with cerebrospinal fluid biomarkers of Alzheimer's disease: A preliminary study in a Croatian cohort.

Brain Behav 2018 Nov 17;8(11):e01128. Epub 2018 Oct 17.

Department for Neuroscience, Croatian Institute for Brain Research, University of Zagreb Medical School, Zagreb, Croatia.

Introduction: Alzheimer's disease (AD) is the world leading cause of dementia. Early detection of AD is essential for faster and more efficacious usage of therapeutics and preventive measures. Even though it is well known that one ε4 allele of apolipoprotein E gene increases the risk for sporadic AD five times, and that two ε4 alleles increase the risk 20 times, reliable genetic markers for AD are not yet available. Read More

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November 2018
2 Reads
1 Citation

Effects of dietary marigold extract on lutein content, yolk color and fatty acid profile of omega-3 eggs.

J Sci Food Agric 2018 Oct 16. Epub 2018 Oct 16.

Scientific Center of Excellence for Personalized Health Care, Science Unit for Research, Production and Medical Testing of Functional Food, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia.

Background: Lutein is a plant pigment very important for eye health in humans. Its bioavailability in humans is better from egg yolk than from dietary supplements. The aim of this research was to determine the influence of lutein (marigold extract powder) supplemented to laying hens' feed rich in omega-3 fatty acids on the content of lutein, fatty acid profile in egg yolks and yolk color. Read More

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October 2018
4 Reads

Effect of n-3 long-chain polyunsaturated fatty acids supplementation in healthy mothers on DHA and EPA profiles in maternal and umbilical blood: a randomized controlled trial.

J Perinat Med 2018 Oct 13. Epub 2018 Oct 13.

Department of Surgery, Mostar Clinical Hospital Center, School of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina.

Background The objective of the study was to compare the effect of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) dietary supplementation on their concentration in total lipids (TL) and lipid fractions of maternal and umbilical vein (UV) blood. The specific objective was to analyze the impact of EPA and DHA supplementation on pregnancy outcome and neonatal birth weight. Methods Women were randomly single-blinded (randomized controlled trial; ISRCTN36705743) allocated to the group receiving EPA and DHA supplementation (supplemented group) or the group receiving placebo-corn oil (control group) in the time period from January 1st, 2016 until March 1st, 2017. Read More

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October 2018
3 Reads

Patterns of chronic physical multimorbidity in psychiatric and general population.

J Psychosom Res 2018 Nov 25;114:72-80. Epub 2018 Sep 25.

Association for the Improvement of Mental Health Programmes, Geneva, Switzerland.

Objective: A growing body of evidence has demonstrated the high prevalence and complexity of chronic physical multimorbidity defined as ≥2 chronic physical illness in people with psychiatric disorders. The present study aimed to assess differences in the prevalence and patterns of self-reported chronic physical illness and multimorbidity in the general and psychiatric populations.

Methods: We performed a latent class analysis of 15 self-reported chronic physical illnesses on a sample of 1060 psychiatric patients and 837 participants from the general population. Read More

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November 2018
6 Reads

New species and records of the Pericoma trifasciata group from Croatia (Diptera: Psychodidae).

Zootaxa 2018 Sep 26;4486(1):76-82. Epub 2018 Sep 26.

Department of biological sciences, Purdue University, 913 West State Street, 47907 West Lafayette, Indiana, USA Department of entomology, University Museum of Bergen, P.O. Box 7800, University of Bergen, N-5040 Bergen, Norway.

Pericoma miljenkoi sp. nov. is described based on adult males from the Plitvička jezera National Park, Croatia. Read More

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September 2018
1 Read

Educational Landscape of Biomedical Informatics in Croatia: Who Are the Teachers and What Are Their Attitudes.

Stud Health Technol Inform 2018 ;255:217-221

Croatian Public Health Institute, Zagreb, Croatia.

Lack of experts with complementary competences in the field of information technology as well as medicine and health care has been recognised as an important obstacle to successful computerisation of the health care system. Using a questionnaire survey, we aimed to describe the current educational landscape of biomedical informatics in Croatia, focussing on teachers' profiles and attitudes about existing educational opportunities in the field. Our findings show that Croatian institutions of higher education should better recognise the need for education in biomedical informatics. Read More

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January 2018

The Content of Biogenic Amines in Croatian Wines of Different Geographical Origins.

Molecules 2018 Oct 9;23(10). Epub 2018 Oct 9.

Department of Chemistry, Faculty of Science, University of Split, Ruđera Boškovića 33, 21000 Split, Croatia.

Samples of white and red wines produced in two different wine-growing regions, coastal (Dalmatia) and continental (Hrvatsko zagorje) of Croatia, were analysed for biogenic amines content. Biogenic amines content was determined, and its concentration levels were associated with the geographical origin of the wine. Due to its high sensitivity, HPLC method with ultraviolet detector was used, including the derivatisation step with dansyl chloride. Read More

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October 2018
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Diagnostic significance of immunoglobulin G avidity in symptomatic and asymptomatic West Nile virus infection.

Rev Soc Bras Med Trop 2018 Sep-Oct;51(5):591-595

OIE Reference Centre for West Nile Disease, Istituto Zooprofilattico Sperimentale "G. Caporale", Teramo, Italy.

Introduction: West Nile virus (WNV) immunoglobulin M (IgM) antibodies have been shown to persist for up to 500 days in certain patients. To evaluate the usefulness of immunoglobulin G (IgG) avidity assessment in the diagnosis of WNV infection, we analyzed 54 WNV IgM- and/or IgG-positive serum samples from 39 patients with neuroinvasive disease and 15 asymptomatic cases tested during a seroprevalence investigation.

Methods: Serological tests (WNV IgM/IgG antibody detection, IgG avidity) were performed using commercially available enzyme-linked immunosorbent assays. Read More

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October 2018
3 Reads