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World Neurosurg 2019 Jan 28. Epub 2019 Jan 28.

Section of Neurosurgery, The University of Chicago Medicine and Biological Sciences, 5841 S. Maryland Avenue, Chicago, IL. Electronic address:

Background: The differential diagnosis of sellar masses includes adenoma, meningioma, craniopharyngioma, and metastasis. Seldom is primary paraganglioma considered. Here we present a case of this unique pathology, review the relevant literature and compile a compendium of immunohistochemical characteristics for use as a resource. Read More

Endocr Relat Cancer 2019 Jan 1. Epub 2019 Jan 1.

J Martinez-Barbera, Institute of Child Health, Developmental Biology and Cancer Programme Birth Defects Research Centre, University College London, 30 Guilford Street , London, United Kingdom of Great Britain and Northern Ireland.

Pharmacological inhibition of the sonic hedgehog (SHH) pathway can be beneficial against certain cancers but detrimental in others. Adamantinomatous craniopharyngioma (ACP) is a relevant pituitary tumour, affecting children and adults, that is associated with high morbidity and increased mortality in long-term follow up. We have previously demonstrated overactivation of the SHH pathway in both human and mouse ACP. Read More

J Neurosurg Pediatr 2019 Jan 11:1-8. Epub 2019 Jan 11.

Departments of1Plastic Surgery.

OBJECTIVECranial base development plays a large role in anterior and vertical maxillary growth through 7 years of age, and the effect of early endonasal cranial base surgery on midface growth is unknown. The authors present their experience with pediatric endoscopic endonasal surgery (EES) and long-term midface growth.METHODSThis is a retrospective review of cases where EES was performed from 2000 to 2016. Read More

Tijdschr Psychiatr 2019 ;61(1):53-56

A craniopharyngioma is a rare, slow-growing tumour in the pituitary gland. Brain tumours usually present with obvious neurological or other physical symptoms, whereas psychiatric symptoms as primary signs are rare. The presented case, in which psychosis and behavioural problems predominated, concerned a 42-year-old patient. Read More

BMC Neurol 2019 Jan 7;19(1). Epub 2019 Jan 7.

Department of Electronic Engineering, Fudan University, Shanghai, China.

Background: Frequent somatic mutations of BRAF and CTNNB1 were identified in both histological subtypes of craniopharyngioma (adamantinomatous and papillary) which shed light on target therapy to cure this oncogenic disease. The aim of this study was to investigate the noninvasive MRI-based radiomics diagnosis to detect BRAF and CTNNB1 mutations in craniopharyngioma patients.

Methods: Forty-four patients pathologically diagnosed as adamantinomatous craniopharyngioma (ACP) or papillary craniopharyngioma (PCP) were retrospectively studied. Read More

World Neurosurg 2019 Jan 3. Epub 2019 Jan 3.

Department of Neurosurgery, First Affiliated Hospital, Chongqing Medical University, Yuzhong District, Chongqing, P.R. China. Electronic address:

Objective: To report our experience of the management of 60 patients with craniopharyngioma with endoscopic endonasal surgery (EES) and evaluate the feasibility and safety of EES for craniopharyngiomas.

Methods: The clinical data of 60 patients with craniopharyngioma who underwent EES between November 2014 and December 2017 were analyzed retrospectively. All patients had vascularized nasoseptal flaps, and the most recent 4 patients had "in situ bone flaps" for better skull base reconstruction. Read More

J Family Med Prim Care 2018 Sep-Oct;7(5):963-966

Department of Endocrinology, Faculty of Medicine and Pharmacy, Ibn Zohr University, Agadir, Morocco.

Background: Stature-weight growth delay (SWGD) is a frequent motivation of consultation. It could be a consequence of a known chronic affection, congenital or acquired affection. The purpose of this study is to describe epidemiological, clinical, paraclinical, and etiological aspects of SWGD. Read More

World Neurosurg 2018 Dec 6. Epub 2018 Dec 6.

Department of Neurosurgery, Shinshu University School of Medicine, Matsumoto, Japan.

Superficial siderosis (SS) associated with craniopharyngioma is an extremely rare occurrence. To our knowledge, only three cases have been reported in literature. Two of the cases occurred following resection of the tumor. Read More

J Neurosurg 2018 Oct 1:1-6. Epub 2018 Oct 1.

6Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

OBJECTIVEThe endoscopic endonasal approach has been proposed as a primary surgical strategy for select craniopharyngiomas. However, those tumors that arise from the sella have not been classified with the other craniopharyngioma subtypes in terms of surgical nuances, intraoperative findings, and postoperative outcomes. The authors describe their experience with a select subtype of craniopharyngioma arising within the sella subjacent to the diaphragma sellae and refer to these tumors as type 0. Read More

J Endocrinol Invest 2018 Nov 24. Epub 2018 Nov 24.

Department of Pediatrics and Pediatric Hematology/Oncology, University Children's Hospital, Klinikum Oldenburg AöR, 26133, Oldenburg, Germany.

Purpose: Periostin is highly expressed in craniopharyngioma (CP)-associated fibroblasts and has been identified as a marker for non-alcoholic fatty liver disease (NAFLD). Half of CP patients with hypothalamic syndrome develop NAFLD. We hypothesized that periostin concentration is elevated in biological fluids of CP and associated with pathological hepatic parameters, indicating increased risk for NAFLD. Read More

Indian J Psychiatry 2018 Jul-Sep;60(3):355-357

Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.

Rapidly progressive dementia (RPD) is generally obvious to family member but often difficult for physicians to pinpoint the underlying pathology. Some common causes, such as prion's disease, Alzheimer's disease, central nervous system vasculitis, or infection, might present with disease-specific signs or symptoms where many etiologies do not produce such warning signs. Here, we are presenting a case who attended the psychiatric clinic for decreased motivation to do work, easy fatigability, infrequent falls, recent memory impairment, increased appetite, polydipsia and polyuria, and provisionally diagnosed with RPD. Read More

J Chem Neuroanat 2018 Dec 17;94:93-101. Epub 2018 Oct 17.

Department of Neurophysiology, National Institute of Mental Health and Neuro Sciences, Hosur Road, Bangalore, 560 029, India. Electronic address:

Craniopharyngiomas (CPs) are rare, epithelial tumors of the central nervous system (CNS) that could lead to manifestation of multiple post-operative symptoms, ranging from hormonal imbalance to obesity, diabetes, visual, neurological and neurocognitive impairments. CP is more frequent in children, and has been reported in middle aged adults as well. In fact, arterial laceration and/or brain stroke which may occur following the removal of some CPs is mainly due to calcification of that CPs along with strong attachments to the blood vessels. Read More

J Clin Neurosci 2019 Jan 14;59:318-324. Epub 2018 Oct 14.

Institute of Neurosurgery, Catholic University School of Medicine, Rome, Italy.

Xanthogranulomas are rare intracranial lesions with controversial etiology. The sellar location is exceedingly rare. Here we report a clinical case and a review of the English-language literature of histologically confirmed xanthogranulomas in order to furnish useful tools in diagnosis and management of this unusual disease. Read More

World Neurosurg 2019 Jan 13;121:211-216. Epub 2018 Oct 13.

Department of Neurosurgery, Medstar Washington Hospital Center, Washington, DC, USA.

Background: Different diseases may occur within the same anatomic space and invade one another. Lesions of this nature are described as collision tumors. Collision tumors of the sella are rare, with pituitary adenoma-craniopharyngiomas having been described in only 15 cases. Read More

J Craniomaxillofac Surg 2018 Dec 24;46(12):2017-2021. Epub 2018 Sep 24.

Anna Meyer Hospital (Azienda Ospedaliero Universitaria Meyer), Neurosurgery Department, Florence, Italy.

Object: At present, a minimally invasive endoscopic endonasal approach is considered an efficient option for lesions affecting the anterior and middle skull base with sellar and parasellar region involvement. In this study we will retrospectively analyze the pediatric patients that we have been treating in the same medical center for the past four years, using an endoscopic approach in the skull base.

Methods: We performed a retrospective chart and imaging review of pediatric patients who underwent endoscopic endonasal skull base surgery (ESBS) at the Meyer Children's Hospital, (Azienda Ospedaliero Universitaria Meyer), in Florence, from January 2012 to July 2016. Read More

J Pediatr Endocrinol Metab 2018 Oct;31(10):1161-1164

Department of Pediatrics, Faculty of Medicine, University of Yamanashi, Shimokato, Chuo, Yamanashi, Japan.

Background Xanthogranuloma of the sellar region is a rare entity. Its pathology is controversial and it is difficult to strictly differentiate it from craniopharyngioma or Rathke's cyst. Case presentation We report a case of xanthogranuloma accompanied by growth hormone deficiency in an 11-year-old girl. Read More

Int J Obes (Lond) 2018 Sep 4. Epub 2018 Sep 4.

Department of Endocrinology, Skåne University Hospital, Lund, Sweden.

Background/objectives: Hypothalamic obesity (HO) occurs in 50% of patients with the pituitary tumor craniopharyngioma (CP). Attempts have been made to predict the risk of HO based on hypothalamic (HT) damage on magnetic resonance imaging (MRI), but none have included volumetry. We performed qualitative and quantitative volumetric analyses of HT damage. Read More

Childs Nerv Syst 2019 Jan 27;35(1):53-61. Epub 2018 Aug 27.

Department of Neurosurgery, Policlinico Universitario "G. Martino", University of Messina, 98125, Messina, Italy.

Purpose: Craniopharyngiomas account for 5.6-13% of intracranial tumors in children. Despite being histologically benign, these tumors remain a major neurosurgical challenge because of the typical tight adherence to adjacent critical structures. Read More

Medicine (Baltimore) 2018 Aug;97(34):e11746

Department of Neurosurgery, PLA General Hospital, Beijing, China.

This study aimed to summarize the clinical experiences and postoperative effects of microsurgical approaches for craniopharyngioma.A total of 183 craniopharyngioma patients who underwent microsurgical treatment since March 2009 to March 2015 in our hospital were included in current research. Surgical approaches were selected based on preoperative evaluations, including tumor locations, sizes, and growth patterns. Read More

Cureus 2018 Jun 20;10(6):e2849. Epub 2018 Jun 20.

Neurosurgery, Taipei Veterans General Hospital, Taipei, TWN.

Choroid plexus papillomas (CPPs) are slow-growing and benign tumors, representing less than 1% of all intracranial neoplasms. They are predominantly located in the lateral ventricles in children, and in the fourth ventricle in adults. Primary CPP over sellar regions is extremely rare. Read More

Childs Nerv Syst 2019 Jan 1;35(1):169-173. Epub 2018 Aug 1.

Department of Haematology/Oncology, Royal Manchester Children's Hospital, Oxford Road, Manchester, England, M13 9WL, UK.

Introduction: Craniopharyngiomas are one of the most frequently diagnosed hypothalamo-pituitary tumors in childhood. The adamantinomatous histological subtype accounts for most pediatric cases, while the papillary variant is almost exclusively diagnosed in adults. Here, we report a case of papillary craniopharyngioma in a very young child, confirmed by molecular tissue analysis. Read More

Pituitary 2018 Oct;21(5):499-506

Department of Neurosurgery, Istituto Scientifico San Raffaele, Vita-Salute University, Via Olgettina 60, 20132, Milano, Italy.

Purpose: The optimal management of residual or recurring craniopharyngioma is still a matter of debate even though adjuvant radiation therapy plays a crucial role. Aim of our study is to report the results of single fraction or multisession Gamma Knife radiosurgery (GKRS) in patients with craniopharyngioma.

Methods: We included 50 consecutive patients treated from 1994 to 2016. Read More

J Neurooncol 2018 Oct 9;140(1):135-143. Epub 2018 Jul 9.

Department of Neurosurgery, Seoul National University College of Medicine, Seoul National University Hospital, 101 Daehak-ro Jongno-gu, Seoul, 03080, Republic of Korea.

Object: To analyze the outcomes of gamma knife radiosurgery (GKS) for craniopharyngiomas and elucidate the optimal strategy.

Methods: Between 1998 and 2016, 35 patients underwent GKS for the treatment of 40 recurrent or residual craniopharyngiomas. Among 40 GKSs, 22 procedures were single-session GKSs and 18 procedures were fractionated GKSs. Read More

Australas Phys Eng Sci Med 2018 Sep 9;41(3):697-711. Epub 2018 Jul 9.

Department of Neurosurgery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Over 90% of craniopharyngeal brain tumors are cystic, which enables the injection of beta emitters such as phosphorus-32 (P) radio-colloid into cysts for their treatment. The aim of this study was to evaluate the clinical and theoretical modelling of Bremsstrahlung radiation dose resulting from stereotactic radio-colloid therapy of cystic craniopharyngioma tumors with P. P radio-colloid with appropriate activity concentration was injected to a head phantom, and then the Bremsstrahlung radiation spectrum and planar images were obtained using a gamma camera. Read More

Medicine (Baltimore) 2018 Jun;97(26):e11136

Department of Neurosurgery, Navy General Hospital, Beijing, China.

To investigate the relationship of the expression of vascular endothelial growth factor (VEGF)/vascular endothelial growth factor receptor-2 (VEGFR-2) and imaging features with the therapeutic efficacy of Phosphorus-32 colloid interstitial radiotherapy in recurrent craniopharyngioma.Thirty-two patients with recurrent craniopharyngioma underwent phosphorus-32 colloid interstitial radiotherapy. The tumor imaging features were classified into 4 types according to the thickness of the cyst wall and signals of the cyst contents as shown by computed tomography (CT) and magnetic resonance imaging (MRI) images. Read More

World Neurosurg 2018 Sep 20;117:332-338. Epub 2018 Jun 20.

Department of Neurosurgery, Tokyo Women's Medical University, Tokyo, Japan.

Background: Malignant craniopharyngioma or anaplastic craniopharyngioma was first reported in 1987 by Akachi and colleagues. It has malignant clinical and histological features, remarkably rapid progression, atypical pathology like squamous cell carcinoma, and a poor prognosis. To date, 17 cases of malignant craniopharyngioma have been reported, most of which were secondary malignant tumors. Read More

Int Forum Allergy Rhinol 2018 Oct 19;8(10):1132-1135. Epub 2018 Jun 19.

Department of Otolaryngology, University of Pittsburgh Medical Center, Pittsburgh, PA.

Background: Inadvertent lateralization of the middle turbinate (MT) after endoscopic sinus surgery (ESS) is cited as a common complication that results in both outflow tract obstruction and recurrent symptoms. In endoscopic endonasal skull-base surgery, the MT is frequently lateralized during the parasagittal approach. Little is known about whether this strategy has unintended consequences on the adjacent paranasal sinuses. Read More

Medicine (Baltimore) 2018 Jun;97(24):e10932

Department of Otolaryngology-Head and Neck Surgery, Kyorin University School of Medicine, Tokyo, Japan.

Rationale: Paraneoplastic limbic encephalitis (PLE) is a rare disorder of the nervous system associated with malignant disease. It has a subacute onset with the following symptoms: cognitive dysfunction, seizures, irritability, hallucinations, and short-term memory loss. Herein, we report the case of a 35-year-old man with PLE, an olfactory neuroblastoma (ONB) admixed with craniopharyngioma, and serum anti-Hu antibodies. Read More

Medicine (Baltimore) 2018 Jun;97(24):e10840

Department of Neurosurgery, PLA General Hospital, Beijing, China.

The aim of the study was to explore anterior interhemispheric approach microsurgery for removing large sellar region tumors.A total of 118 patients with large sellar region tumors were treated with the anterior interhemispheric approach microsurgery. There were 58 craniopharyngioma, 37 pituitary adenoma, 5 hypothalamic glioma, 7 meningioma, and 11 other tumors cases. Read More

Neurol Med Chir (Tokyo) 2018 Jun 6;58(6):260-265. Epub 2018 Jun 6.

Department of Hypothalamic and Pituitary Surgery, Toranomon Hospital.

Subdiaphragmatic type craniopharyngiomas are tumors that originate within the sella. They are divided into two types; those localized within an enlarged sella (intrasellar type) and those accompanying a suprasellar extension (suprasellar extended type). The clinicopathological features and the recent outcomes of endoscopic endonasal surgery were retrospectively reviewed in 32 patients, with 11 surgeries for recurrence. Read More

J Neurol Surg A Cent Eur Neurosurg 2018 Sep 5;79(5):436-441. Epub 2018 Jun 5.

Department of Neurosurgery, Tohoku University Graduate School of Medicine, Sendai, Japan.

Nonobstructive hydrocephalus in patients with craniopharyngiomas is uncommon. We describe our surgical series of 25 consecutive patients with craniopharyngioma who presented with hydrocephalus. Obstructive hydrocephalus was evident in most cases, and nonobstructive hydrocephalus was revealed in three cases. Read More

J Clin Neurosci 2018 Aug 24;54:143-145. Epub 2018 May 24.

Department of Radiology and Imaging Sciences, Division of Neuroradiology, Emory University School of Medicine, Atlanta, GA, United States.

Fusiform dilatation of the internal carotid artery (FDICA) is a well-described radiographic finding following resection of childhood craniopharyngioma (CP). A 39-year-old woman with right-sided FDICA was successfully treated for lesion enlargement with endovascular flow diversion, which has not been described in the literature. Read More

PLoS One 2018 24;13(5):e0197895. Epub 2018 May 24.

Institute of Radiology, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany.

Purpose: Adamantinomatous craniopharyngiomas (ACP) as benign sellar brain tumors are challenging to treat. In order to develop robust in vivo drug testing methodology, the murine orthotopic craniopharyngioma model (PDX) was characterized by magnetic resonance imaging (MRI) and histology in xenografts from three patients (ACP1-3).

Methods: In ACP PDX, multiparametric MRI was conducted to assess morphologic characteristics such as contrast-enhancing tumor volume (CETV) as well as functional parameters from dynamic contrast-enhanced MRI (DCE-MRI) and diffusion-weighted imaging (DWI) including area-under-the-curve (AUC), peak enhancement (PE), time-to-peak (TTP) and apparent diffusion coefficient (ADC). Read More

J Clin Endocrinol Metab 2018 07;103(7):2424-2429

Neurosurgery, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.

Context: The persisting embryonal infundibular recess (PEIR) is a rare anomaly of the floor of the third ventricle with a debated pathogenesis. It can be a cause of misdiagnosis in the case of cystic lesions of the sellar and suprasellar area.

Objective: To describe two recently evaluated cases and provide a systematic literature review. Read More

J Neurosurg 2018 May 1:1-15. Epub 2018 May 1.

3Pacific Pituitary Disorders Center, John Wayne Cancer Institute, Providence Saint John's Health Center, Santa Monica, California.

OBJECTIVEThe authors previously described a graded approach to skull base repair following endonasal microscopic or endoscope-assisted tumor surgery. In this paper they review their experience with skull base reconstruction in the endoscopic era.METHODSA retrospective review of a single-institution endonasal endoscopic patient database (April 2010-April 2017) was undertaken. Read More

Int J Radiat Oncol Biol Phys 2018 Jul 29;101(4):854-859. Epub 2018 Mar 29.

Department of Radiation Oncology, University of Florida College of Medicine, Jacksonville, Florida. Electronic address:

Purpose: To estimate the rate of and identify risk factors for vasculopathy after proton therapy in pediatric patients with central nervous system and skull base tumors.

Methods And Materials: Between 2006 and 2015, 644 pediatric patients with central nervous system and skull base tumors were treated with proton therapy at a single institution. The 3 most common histologies were craniopharyngioma (n = 135), ependymoma (n = 135), and low-grade glioma (n = 131). Read More

Surg Neurol Int 2018 9;9:76. Epub 2018 Apr 9.

Department of Neuro-Surgery, Govind Ballav Pant Institute of Postgraduate Medical Education and Research (GIPMER), New Delhi, India.

Background: Chondrosarcoma is a mesenchymal malignant tumor composed of tumor cells producing cartilage. It is more commonly found in older age group and usually affects the axial skeleton. Intracranial chondrosarcoma is extremely rare, and chondrosarcoma arising from the sellar region are even rarer with only a few cases described in the literature. Read More

J Neurosurg 2018 Apr 1:1-5. Epub 2018 Apr 1.

2Neurology.

The authors present the case of a man with a papillary craniopharyngioma, first diagnosed at 47 years of age, who experienced multiple recurrences. Review of the pathologic specimen from his first resection demonstrated the BRAF V600E mutation. With his most recent recurrence following previous surgery and radiotherapy, at 52 years of age, the decision was made to initiate treatment with the BRAF V600E inhibitor dabrafenib. Read More

Pituitary 2018 Aug;21(4):393-405

Department of Pathology and Clinical Bacteriology, Jakob Erdheim Institute, Vienna, Austria.

A heterogeneous group of epithelial cystic tumors developed at the infundibulum and the third ventricle disconcerted pathologists at the dawn of the twentieth century. Very little was known at that time about the physiological role played by the pituitary gland, and there was almost complete ignorance regarding the function of the hypothalamus. Acromegaly, or enlargement of acral body parts, described in 1886 by Pierre Marie, was the only disease linked to primary hypertrophies of the pituitary gland, known as "pituitary strumas". Read More

Endocrinol Diabetes Metab Case Rep 2018 28;2018. Epub 2018 Mar 28.

Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.

Co-existence of craniopharyngioma and acromegaly has been very rarely reported. A 65-year-old man presented with visual deterioration, fatigue and frontal headaches. Magnetic resonance imaging revealed a suprasellar heterogeneous, mainly cystic, 1. Read More

Eur J Endocrinol 2018 Jun 29;178(6):577-587. Epub 2018 Mar 29.

Department of EndocrinologySkåne University Hospital, Lund, Sweden

Context: Patients with craniopharyngioma (CP) and hypothalamic lesions (HL) have cognitive deficits. Which neural pathways are affected is unknown.

Objective: To determine whether there is a relationship between microstructural white matter (WM) alterations detected with diffusion tensor imaging (DTI) and cognition in adults with childhood-onset CP. Read More

J Neurol Surg B Skull Base 2018 04 19;79(Suppl 3):S279-S280. Epub 2018 Feb 19.

Department of Neurological Surgery, Wexner Medical Center, The Ohio State University, Columbus, Ohio, United States.

A 49-year-old female presented with intense headaches of 3 months duration. Brain magnetic resonance imaging (MRI) was performed and showed a sellar-suprasellar lesion extending into the third ventricle. A presumptive diagnosis of a craniopharyngioma was made. Read More

J Neurol Surg B Skull Base 2018 Apr 8;79(Suppl 3):S259-S260. Epub 2018 Feb 8.

Department of Neurosurgery, George Washington University, Washington, District of Columbia, United States.

 To demonstrate the transchoroidal approach for the resection of a recurrent craniopharyngioma.  Video case report.  Microsurgical resection. Read More

J Neurol Surg B Skull Base 2018 Apr 8;79(Suppl 3):S256-S258. Epub 2018 Feb 8.

Department of Neurosciences, Neurosurgery Section, University of Padua, Padua, Italy.

 Ideal treatment of craniopharyngiomas is still controversial. Radiotherapy (RT) is considered effective for recurrences or after subtotal tumor removal (STR). About 40 to 50% of patients may experience tumor cyst expansion soon after RT; in these cases, the role of salvage surgery is debated. Read More

J Neurol Surg B Skull Base 2018 Apr 14;79(Suppl 3):S247-S248. Epub 2018 Feb 14.

Department of Neurosurgery, Louisiana State Health Sciences Center - Shreveport, Shreveport, Louisiana, United States.

 Complete surgical resection is an important prognostic factor for recurrence and is the best management for craniopharyngioma. This operative video demonstrates the technical nuances in achieving complete resection of a suprasellar craniopharyngioma.  The surgery was performed in a middle-aged lady who presented with the history of progressive bitemporal hemianopia and excessive sleepiness over 8 months. Read More

J Neurol Surg B Skull Base 2018 Apr 25;79(Suppl 3):S241-S242. Epub 2018 Jan 25.

Department of Neurosugery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States.

 The current video presents the nuances of an endoscopic endonasal approach to a suprasellar craniopharyngioma.  The video analyzes the presentation, preoperative workup and imaging, surgical steps and technical nuances of the surgery, the clinical outcome, and follow-up imaging.  The patient was treated by a skull base team consisting of a neurosurgeon and an ENT surgeon, at a teaching academic institution. Read More

J Neurol Surg B Skull Base 2018 Apr 7;79(Suppl 3):S237-S238. Epub 2018 Feb 7.

Department of Neurological Surgery, Wexner Medical Center, The Ohio State University College of Medicine, Columbus, Ohio, United States.

We present the case of a 57-year-old male who presented with progressive right side vision loss whose workup revealed a large suprasellar lesion with invasion of the third ventricle. The pituitary stalk was not visible. Hormonal panel showed no hormonal deficits. Read More

World Neurosurg 2018 Jun 20;114:172-177. Epub 2018 Mar 20.

Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. Electronic address:

Background: Lymphocytic hypophysitis is a rare inflammatory lesion in the sellar region. Lymphocytic hypophysitis secondary to ruptured Rathke cleft cyst (RCC) is even more rarely seen. Clinical characteristics, treatment strategies, and prognosis remain elusive. Read More

Oncol Lett 2018 Apr 7;15(4):4997-5003. Epub 2018 Feb 7.

Institute of Neurosurgery, Navy General Hospital, Beijing 100048, P.R. China.

The present study evaluated drug distribution and clinical safety in treating patients with cystic craniopharyngioma (CP) with intracavitary radiotherapy using phosphorus-32 (P) colloid. In total, 40 patients who were recently diagnosed with primary or recurrent cystic CP were enrolled into the study. Patients underwent stereotactic intracavitary therapy and were administered P colloid and iopamidol-300 (1:1 dilution). Read More

World Neurosurg 2018 Jun 7;114:e306-e316. Epub 2018 Mar 7.

Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address:

Objective: Despite advances in endoscopic techniques, retrochiasmatic craniopharyngiomas (CPs) are difficult to remove completely, because the low-lying optic chiasm often provides an obstacle to an endoscopic endonasal approach. This study aimed to identify the endoscopic surgical outcomes of the retrochiasmatic CP and resolve the issues related to low-lying optic chiasm.

Methods: We reviewed 154 consecutive patients with CP who underwent endonasal endoscopic resection from February 2009 to April 2017 at 2 independent institutions. Read More