5,234 results match your criteria Craniopharyngioma


Neurological and neuropsychological outcome after resection of craniopharyngiomas.

J Neurosurg 2019 Apr 19:1-10. Epub 2019 Apr 19.

OBJECTIVECraniopharyngiomas are rare and benign tumors of the sellar and/or parasellar region. Primary treatment involves resection followed by adjuvant radiotherapy. While the grade of resection was frequently analyzed following surgery, the neurological outcome and especially neuropsychological deficits and quality of life have been neglected for many decades. Read More

View Article

Download full-text PDF

Source
https://thejns.org/view/journals/j-neurosurg/aop/article-10.
Publisher Site
http://dx.doi.org/10.3171/2018.10.JNS181557DOI Listing
April 2019
1 Read

An Extended Endoscopic Endonasal Approach for Sellar Area Chondrosarcoma: A Case Report and Literature Review.

World Neurosurg 2019 Apr 14. Epub 2019 Apr 14.

Department of Neurosurgery, the First Affiliated Hospital of Fujian Medical University, Fuzhou, People's Republic of China.

Background: Chondrosarcoma is a malignant tumor that originates from mesenchymal cells that have differentiated into chondrocytes, often growing laterally, rarely seen in the cranium, and seldom seen in the saddle area. We believe that only a few cases have been reported in the literature. We report a case of pituitary fossa chondrosarcoma, which was completely resected by an extended endoscopic endonasal approach, and a literature review. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.wneu.2019.04.075DOI Listing
April 2019
1 Read

Intraoperative finding of an Anterior Communicating Artery Blister-like Aneurysm during a Primary Craniopharyngioma Resection: Accidental or Incidental?

World Neurosurg 2019 Apr 12. Epub 2019 Apr 12.

Department of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing, People's Republic of China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.wneu.2019.04.067DOI Listing
April 2019
1 Read

Clinical diagnosis of attention-deficit/hyperactivity disorder in survivors of pediatric brain tumors.

J Neurooncol 2019 Apr 13. Epub 2019 Apr 13.

Division of Oncology, Children's Hospital of Philadelphia, 3501 Civic Center Blvd., 10211 CTRB, Philadelphia, PA, 19104, USA.

Purpose: Survivors of pediatric brain tumors often have neurodevelopmental late effects, such as inattention. Symptoms may mirror those of attention-deficit/hyperactivity disorder (ADHD), which affects ~ 5-8% of the general population. This retrospective study of survivors followed at a large tertiary care center examined the prevalence of a clinical diagnosis of ADHD, and risk factors associated with ADHD diagnosis and ADHD-related medication use. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s11060-019-03165-4
Publisher Site
http://dx.doi.org/10.1007/s11060-019-03165-4DOI Listing
April 2019
2 Reads

International consensus statement on endoscopic skull-base surgery: executive summary.

Int Forum Allergy Rhinol 2019 Apr 8. Epub 2019 Apr 8.

Department of Otolaryngology, School of Medicine, University of North Carolina,, Chapel Hill, NC.

Background: Endoscopic skull-base surgery (ESBS) is a rapidly growing discipline that often combines the expertise of otolaryngology-head and neck surgeons and neurosurgeons to provide care for these challenging conditions. As the field has grown, so too has the literature evaluating this surgical approach and the challenges and complications associated with these interventions. An international, multidisciplinary effort to critically evaluate and grade the current literature on ESBS has resulted in the International Consensus Statement on Endoscopic Skull Base Surgery (ICAR:SB). Read More

View Article

Download full-text PDF

Source
https://onlinelibrary.wiley.com/doi/abs/10.1002/alr.22327
Publisher Site
http://dx.doi.org/10.1002/alr.22327DOI Listing
April 2019
3 Reads

Endocrine and Visual Outcomes Following Gross Total Resection and Subtotal Resection of Adult Craniopharyngioma: Systematic Review and Meta-analysis.

World Neurosurg 2019 Apr 1. Epub 2019 Apr 1.

Department of Neurosurgery, Mayo Clinic, Jacksonville, Florida. Electronic address:

Background: The optimal surgical strategy for management of adult patients with craniopharyngioma remains controversial.

Objective: To analyze the functional outcomes of adult patients with gross total resection (GTR) and subtotal resection (STR) of craniopharyngioma.

Methods: MEDLINE, EMBASE, Scopus, and Cochrane databases were searched from inception to July 19, 2018 for articles comparing post-operative endocrine function, vision, complications, and recurrence rates for adult patients with GTR and STR of craniopharyngioma. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S18788750193091
Publisher Site
http://dx.doi.org/10.1016/j.wneu.2019.03.239DOI Listing
April 2019
3 Reads
2.417 Impact Factor

Diencephalic Syndrome as Presentation of Giant Childhood Craniopharyngioma: Management Review.

J Pediatr Neurosci 2018 Oct-Dec;13(4):383-387

Department of Neurosurgery, Neurosciences Centre, All India Institute of Medical Sciences, New Delhi, India.

Diencephalic syndrome (DES) is an extremely uncommon occurrence, and approximately 100 cases have been reported. It presents as a failure to thrive in infants and children but rarely occurs in adult population. The characteristic clinical features of DES include severely emaciated body, normal linear growth and normal or precocious intellectual development, hyperalertness, hyperkinesis, and euphoria usually associated with intracranial sellar-suprasellar mass lesion, usually optico-chiasmatic glioma or hypothalamic mass. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/JPN.JPN_179_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413612PMC
April 2019
2 Reads

Optic Tract Edema: A Rare Entity in Pituitary Macroadenoma.

Asian J Neurosurg 2019 Jan-Mar;14(1):307-309

Department of Neurosurgery, Command Hospital (Southern Command), Pune, Maharashtra, India.

Pituitary tumors are relatively common tumors accounting for almost 15% of all primary brain tumors. Pituitary macroadenomas cause mass effect on the optic apparatus causing a myriad of visual deficits. On imaging generally the anterior visual pathway is involved which may be compressed by the mass lesion. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/ajns.AJNS_178_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417355PMC
April 2019
1 Read

Posterior hypothalamus-sparing surgery improves outcome after childhood craniopharyngioma.

Endocr Connect 2019 Mar 1. Epub 2019 Mar 1.

H Müller, Department of Pediatrics and Pediatric Hematology / Oncology, University Children's Hospital, Klinikum Oldenburg AöR, Oldenburg, Germany.

Objective: Quality of life (QoL) is frequently impaired in childhood-onset craniopharyngioma (CP) by hypothalamic syndrome. The debate, whether pretreatment hypothalamic involvement (HI) has apriori prognostic impact or surgical hypothalamic lesions (HL) determine outcome, is controversial.

Design: Survival and outcome of CPs recruited 2007-2014 in KRANIOPHARYNGEOM 2007 were analyzed with regard to reference-confirmed presurgical HI and surgical HL. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1530/EC-19-0074DOI Listing

Pediatric craniopharyngioma in association with familial adenomatous polyposis.

Fam Cancer 2019 Mar 27. Epub 2019 Mar 27.

Morgan Adams Neuro-Oncology Program, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, CO, USA.

Familial adenomatous polyposis (FAP) is a cancer predisposition syndrome driven by germline loss-of-function of the APC gene and phenotypically manifests with intestinal polyposis and a variety of extra-intestinal bone and soft tissue tumors. Craniopharyngioma is not a well-described FAP-associated tumor, however, six cases have been reported in adults, all demonstrating ectopic location and adamantinomatous histology. We report the first case of craniopharyngioma associated with FAP in a pediatric patient. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s10689-019-00126-8
Publisher Site
http://dx.doi.org/10.1007/s10689-019-00126-8DOI Listing
March 2019
3 Reads

Hypothalamic Obesity: Prologue and Promise.

Horm Res Paediatr 2019 Mar 18:1-9. Epub 2019 Mar 18.

Division of Endocrinology, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

Hypothalamic obesity (HO) frequently occurs following damage to the medial hypothalamic region, encompassing the arcuate nucleus, the paraventricular nucleus, the ventromedial nucleus, the dorsomedial nucleus, and the dorsal hypothalamic area, which are critically involved in the regulation of satiety and energy balance through neural and humoral connections. HO is most commonly described in the context of craniopharyngioma and its treatment, but it can also occur following other suprasellar tumors, radiation, trauma, or a surgical insult to the hypothalamus. A constellation of loss of satiety and a reduction of the metabolic rate, thermogenesis, and physical activity as well as increased vagal tone and hyperinsulinism with insulin and leptin resistance results in rapid weight gain due to a decreased energy expenditure and increased energy storage in adipose cells. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000496564DOI Listing
March 2019
1 Read

Immune microenvironment of primary and recurrent craniopharyngiomas: A study of the differences and clinical significance.

World Neurosurg 2019 Mar 14. Epub 2019 Mar 14.

Department of Neurosurgery, the First Affiliated Hospital, Fujian Medical University, Fuzhou, China; Department of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing, China. Electronic address:

Objective: This study explored the differences between the immune microenvironments of primary and recurrent craniopharyngiomas (CPs). In addition, we investigated the relationship between the immune microenvironment and clinical characteristics of CP.

Methods: We collected 52 specimens from 26 patients with CPs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.wneu.2019.02.212DOI Listing
March 2019
1 Read

An ectopic recurrent craniopharyngioma of the temporal lobe: Case report and review of the literature.

World Neurosurg 2019 Mar 12. Epub 2019 Mar 12.

Department of Neurosurgery, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, PR.China. Electronic address:

Background: Ectopic recurrent craniopharyngioma is rare. We present a case of temporal ectopic recurrent tumor after trans-eyebrow supraorbital keyhole approach and provide a literature review with basic statistics.

Method: We retrospectively reviewed 57 cases of craniopharyngiomas operated on at our institution. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.wneu.2019.02.196DOI Listing
March 2019
1 Read

Two cases of pulsatile tinnitus: Key points for the clinician.

Eur Ann Otorhinolaryngol Head Neck Dis 2019 Mar 11. Epub 2019 Mar 11.

ENT department, CHU Saint-Pierre, 322, rue Haute, 1000 Bruxelles, Belgium.

Introduction: Pulsatile tinnitus is a sound generated by an acoustic source from within the body, which is perceived by the auditory system of the patient.

Cases Summary: We report two puzzling cases of pulsatile tinnitus with normal ENT examinations: the first was due to a cervical internal carotid artery dissection, and the second to the compression of the foramina of Monro by a craniopharyngioma, leading to hydrocephalus.

Discussion: We review the systematic management and emphasize the decisive role of the ENT clinician regarding this pulsatile tinnitus complaint, because of the potentially severe complications of its underlying pathology. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.anorl.2018.09.009DOI Listing

Diagnostic accuracy of neuroimaging in pediatric optic chiasm/sellar/suprasellar tumors.

Pediatr Blood Cancer 2019 Jun 8;66(6):e27680. Epub 2019 Mar 8.

Morgan Adams Foundation Pediatric Brain Tumor Research Foundation, Aurora, Colorado.

Preoperative diagnosis for tumors arising in the optic chiasm/sellar/suprasellar region in children is helpful to determine surgical necessity and approach, given the high operative risk in this area. We evaluated the ability to differentiate tumor type by preoperative neuroimaging. Thirty-eight of 53 tumors were correctly diagnosed by neuroimaging based on final pathologic diagnosis (prediction accuracy 72%). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pbc.27680DOI Listing
June 2019
3 Reads

Radiological and endocrinological evaluations with grading of hypothalamic perifocal edema caused by craniopharyngiomas.

Pituitary 2019 Apr;22(2):146-155

Department of Neurosurgery, Graduate School of Medical Science, Kanazawa University, 13-1, Takara-machi, Kanazawa, Ishikawa, 920-8641, Japan.

Introduction: Hypophysial and hypothalamic dysfunction caused by craniopharyngioma is a serious problem despite the progress of surgical approaches and techniques. Perifocal edema induced by craniopharyngioma could be speculated as a potential factor resulting in pre- and post-operative hypophysial and hypothalamic dysfunction, as well as, their anatomical involvement.

Methods: Medical records of 54 patients with craniopharyngioma were retrospectively reviewed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11102-019-00945-zDOI Listing
April 2019
1 Read

Treatment of Hypothalamic Obesity with Dextroamphetamine: A Case Series.

Obes Facts 2019 7;12(1):91-102. Epub 2019 Mar 7.

Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics and Adolescent Medicine, University Medical Center, Ulm, Germany.

Background: A limited number of published case reports suggest a positive effect of dextroamphetamine, an adrenergic agonist affecting both the central nervous system (CNS) and peripheral nervous system, on physical activity and weight in patients with hypothalamic obesity (intractable obesity following CNS insult). Here, we present our clinical experience with dextroamphetamine treatment for hypothalamic obesity.

Methods: The clinical course of all patients started on dextroamphetamine treatment for severe hypothalamic obesity at our institution between 2010 and 2013 is reported. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000495851DOI Listing
March 2019
2 Reads

Anterior cerebral artery rupture during extended endoscopic endonasal transsphenoidal approach for severely calcified craniopharyngioma.

World Neurosurg 2019 Mar 4. Epub 2019 Mar 4.

Department of Neurosurgery, Qilu Hospital of Shandong University and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan, Shandong province, China; Shandong Key Laboratory of Brain Function Remodeling, Jinan, Shandong province, China. Electronic address:

Background: This report discusses the risks and complications of using the extended endoscopic endonasal transsphenoidal approach (EEETA) in a special craniopharyngioma case to caution neurosurgeons.

Case Description: A 38-year-old woman with craniopharyngioma underwent the EEETA surgery. Her anterior cerebral artery (ACA) was punctured intra-operatively and clipped by using an aneurysm clip through the nose in an emergency procedure. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.wneu.2019.02.128DOI Listing

Automatic image processing pipeline for tracking longitudinal vessel changes in magnetic resonance angiography.

J Magn Reson Imaging 2019 Mar 7. Epub 2019 Mar 7.

Department of Radiation Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA (Work Origin).

Background: Cerebral vessel diameter changes objectively and automatically derived from longitudinal magnetic resonance angiography (MRA) facilitate quantification of vessel changes and further modeling.

Purpose: To characterize longitudinal changes in intracranial vessel diameter using time-of-flight (TOF) MRA.

Study Type: Retrospective longitudinal study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jmri.26699DOI Listing
March 2019
1 Read

MANAGEMENT OF ENDOCRINE DISEASE: Childhood-onset Craniopharyngioma: state of the art of care in 2018.

Eur J Endocrinol 2019 Feb 1. Epub 2019 Feb 1.

H Müller, Dep. of Pediatrics and Pediatric Hematology / Oncology, Childrens University Hospital Oldenburg, Klinikum Oldenburg AöR, Oldenburg, Germany.

This review presents an update on current concepts of pathogenesis, diagnostics, multidisciplinary treatment, follow-up care, with special focus on neuropsychological sequelae of childhood-onset craniopharyngioma (CP) based on most recent publications on these topics. Recent insight in molecular pathogenesis of CP opens new perspectives on targeted therapy. Further research to elucidate pathogenic mechanisms and hopefully prevent hypothalamic involvement of CP is warranted. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1530/EJE-18-1021DOI Listing
February 2019

Intrachiasmatic craniopharyngioma: Assessment of visual outcome with optical coherence tomography after complete surgical removal.

Surg Neurol Int 2019 21;10. Epub 2019 Jan 21.

Department of Neurosurgery, La Princesa University Hospital, Madrid, Spain.

Background: Optic chiasm invasion by a craniopharyngioma (CP) is exceptional. Surgical treatment of intrachiasmatic CPs associates a high risk of chiasm injury, which should be properly addressed before surgery.

Case Description: We present a 46-year-old woman admitted to the hospital with low visual acuity (0. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/sni.sni_292_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357539PMC
January 2019
1 Read

Efficacy of Direct Revascularization Surgery for Hemorrhagic Moyamoya Syndrome As a Late Complication of Cranial Irradiation for Childhood Craniopharyngioma.

J Stroke Cerebrovasc Dis 2019 May 13;28(5):e46-e50. Epub 2019 Feb 13.

Department of Neurosurgery, Tohoku University, Sendai, Japan.

Moyamoya syndrome (MMS) is an uncommon late complication after cranial irradiation. Its hemorrhagic presentation from the associated pseudo-aneurysm is extremely rare, and the optimal management strategy is undetermined. We herein report a 36-year-old man who developed intraventricular hemorrhage from a pseudo-aneurysm at the extended left anterior choroidal artery as an abnormal collateral of MMS 30 years after surgical removal and cranial irradiation for childhood craniopharyngioma. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2019.01.033DOI Listing
May 2019
2 Reads

Expanded Endonasal Endoscopic Surgery in Suprasellar Craniopharyngiomas: A Retrospective Analysis of 43 Surgeries Including Recurrent Cases.

Oper Neurosurg (Hagerstown) 2019 Feb 15. Epub 2019 Feb 15.

Division of Neurosurgery, Toronto Western Hospital, University Health Network and Department of Surgery, University of Toronto, Toronto, Canada.

Background: The role of expanded endonasal endoscopic surgery for primary and recurrent craniopharyngioma is not yet fully established.

Objective: To report and evaluate our experience with the endoscopic endonasal approach (EEA) for the resection of primary and recurrent craniopharyngiomas.

Methods: This is a retrospective cohort analysis of 43 consecutive EEA procedures in 40 patients operated from September 2006 to February 2012 for suprasellar craniopharyngiomas. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/ons/opy356DOI Listing
February 2019
3 Reads

Awake Surgical Management of Third Ventricular Tumors: A Preliminary Safety, Feasibility, and Clinical Applications Study.

Oper Neurosurg (Hagerstown) 2019 Feb 12. Epub 2019 Feb 12.

Aurora Neuroscience Innovation Institute, Aurora St. Luke's Medical Center, Milwaukee, Wisconsin.

Background: Endoscopic and microneurosurgical approaches to third ventricular lesions are commonly performed under general anesthesia.

Objective: To report our initial experience with awake transsulcal parafascicular corridor surgery (TPCS) of the third ventricle and its safety, feasibility, and limitations.

Methods: A total of 12 cases are reviewed: 6 colloid cysts, 2 central neurocytomas, 1 papillary craniopharyngioma, 1 basal ganglia glioblastoma, 1 thalamic glioblastoma, and 1 ependymal cyst. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/ons/opy405DOI Listing
February 2019
5 Reads

Subfrontal Infrachiasmatic Approach to a Craniopharyngioma Resection: 2-Dimensional Operative Video.

Oper Neurosurg (Hagerstown) 2019 Feb 5. Epub 2019 Feb 5.

Division of Pediatric Neurosurgery, Department of Surgery, Texas Children's Hospital, Department of Neurosurgery, Baylor College of Medicine, Houston, Texas.

Craniopharyngioma constitutes one of the most challenging tumors. The surgery may be the definitive treatment and multiple approaches have been described based on different anatomical considerations. The choice of the right approach is the key to optimize the resection and minimize the risks. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/ons/opy403DOI Listing
February 2019

Lessons learned in the evolution of endoscopic skull base surgery.

J Neurosurg 2019 Feb;130(2):337-346

2Otorhinolaryngology, NewYork-Presbyterian Hospital/Weill Cornell Medicine, New York; and.

OBJECTIVEEndoscopic skull base surgery (ESBS) is a relatively recent addition to the neurosurgical armamentarium. As with many new approaches, there has been significant controversy regarding its value compared with more traditional approaches to ventral skull base pathology. Although early enthusiasm for new approaches that appear less invasive is usually high, these new techniques require rigorous study to ensure that widespread implementation is in the best interest of patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3171/2018.10.JNS182154DOI Listing
February 2019
2 Reads

In Reply to the Letter to the Editor "Craniopharyngioma: 10 Selected Works Which Provide Comprehensive and Valuable Insight into These Complex Tumors".

World Neurosurg 2019 02;122:713-714

Department of Neurological Surgery, Loyola University Stritch School of Medicine, Maywood, Illinois, USA; Department of Otolaryngology, Loyola University Stritch School of Medicine, Maywood, Illinois, USA; Department of Neurological Surgery, Edward Hines, Jr. VA Hospital, Hines, Illinois, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.wneu.2018.10.223DOI Listing
February 2019
2 Reads
2.417 Impact Factor

Craniopharyngioma: 10 Selected Works That Provide Comprehensive and Valuable Insight into These Complex Tumors.

World Neurosurg 2019 02;122:710-712

Department of Neurosurgery, Ramón y Cajal University Hospital, Madrid, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.wneu.2018.09.220DOI Listing
February 2019
3 Reads

[Clinical analysis of endoscopic endonasal approach for removal of sellar tumors].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Nov;32(22):1735-1739

Department of Radiology, Tianjin Huanhu Hospita.

To investigate the safety and efficacy of endoscopic endonasal approach for removal of sellar tumors. The clinical data of 18 patients with sellar tumors undergoing endoscopic endonasal surgery were analyzed retrospectively. This series consisted of ten pituitary adenomas, five craniopharyngiomas, three meningiomas. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.13201/j.issn.1001-1781.2018.22.013DOI Listing
November 2018
3 Reads

Patterns of Care in Pediatric Craniopharyngioma: Outcomes Following Definitive Radiotherapy.

Anticancer Res 2019 Feb;39(2):803-807

Department of Radiation Oncology, University of Nebraska Medical Center, Omaha, NE, U.S.A.

Background/aim: Few data are available on the utility of definitive radiation therapy (RT) for pediatric craniopharyngioma. This study sought to evaluate practice patterns and patient outcomes using the Surveillance Epidemiology and End Results database from 2004-2014.

Materials And Methods: Overall survival (OS) was compared between five treatment groups, definitive radiation therapy (RT), gross total resection (GTR), subtotal resection (STR), STR+RT, and observation/biopsy only, using Kaplan-Meier analysis and log-rank tests. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21873/anticanres.13178DOI Listing
February 2019
1 Read

Adipsic diabetes insipidus secondary to craniopharyngioma resection.

BMJ Case Rep 2019 Jan 31;12(1). Epub 2019 Jan 31.

Fundación Cardioinfantil Instituto de Cardiologia, Bogotá, Colombia.

Adipsic diabetes insipidus is an infrequent disease which may be associated with craniopharyngioma. It may be secondary to the tumour's extension, as well as to resection of the mass. We present the case of a 24-year-old woman with a history of delayed puberty and hypothyroidism, but no prior study reports. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bcr-2018-225903DOI Listing
January 2019
3 Reads

A Case of Primary Sellar Paraganglioma: Immunohistochemistry Resource and Review.

World Neurosurg 2019 Jan 28. Epub 2019 Jan 28.

Section of Neurosurgery, The University of Chicago Medicine and Biological Sciences, 5841 S. Maryland Avenue, Chicago, IL. Electronic address:

Background: The differential diagnosis of sellar masses includes adenoma, meningioma, craniopharyngioma, and metastasis. Seldom is primary paraganglioma considered. Here we present a case of this unique pathology, review the relevant literature and compile a compendium of immunohistochemical characteristics for use as a resource. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.wneu.2019.01.094DOI Listing
January 2019
2 Reads

Comparative evaluation of neuroendocrine dysfunction in children with craniopharyngiomas before and after mass effects are removed.

J Pediatr Endocrinol Metab 2019 Feb;32(2):127-133

Department of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, P.R. China, Phone: +13661307913.

Objective To compare the effects of mass effects in situ (MEIS) and after neurosurgery (ANS) on neuroendocrine function in children with craniopharyngioma. Methods We retrospectively investigated 185 cases of children with craniopharyngioma who underwent neurosurgical treatment at the Beijing Tiantan Hospital from 2011 to 2016. The neuroendocrine function of patients was compared before and after tumor removal. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1515/jpem-2018-0204DOI Listing
February 2019
6 Reads

Growth hormone replacement therapy improves hypopituitarism-associated hypoxemia in a patient after craniopharyngioma surgery: A case report.

Medicine (Baltimore) 2019 Jan;98(3):e14101

Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shuaifuyuan 1, Dong Cheng District, Beijing 100730, China.

Rationale: There are some reports about hypoxemia related to hypopituitarism. However, little is known about the relationship between growth hormone deficiency (GHD) and hypoxemia.

Patients Concerns: A 23-year-old female presented with severe hypoxemia after the operations of craniopharyngioma. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000014101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370160PMC
January 2019
3 Reads

Comparison of neuroendocrine dysfunction in patients with adamantinomatous and papillary craniopharyngiomas.

Exp Ther Med 2019 Jan 12;17(1):51-56. Epub 2018 Nov 12.

Department of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, P.R. China.

Craniopharyngiomas (CPs) are rare epithelial tumors mainly located in the sellar/parasellar region. They may be classified into two major histological subtypes, which exhibit clinical and pathological differences: Adamantinomatous CP (ACP) and papillary CP (PCP). The aim of the present study was to compare the neuroendocrine dysfunction between ACP and PCP prior to and after surgical resection. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3892/etm.2018.6953DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307520PMC
January 2019
3 Reads

Clinical and Radiographic Characteristics of Atypical Slipped Capital Femoral Epiphysis.

J Pediatr Orthop 2019 Jan 14. Epub 2019 Jan 14.

Department of Orthopedic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Background: Slipped capital femoral epiphysis (SCFEs) can be idiopathic or atypical (associated with renal failure, radiation therapy, and endocrine disorders). It is important to estimate the likelihood that atypical SCFE shows different clinical and radiographic characteristics and complications with typical SCFEs.

Methods: We retrospectively reviewed 53 patients (66 hips) with SCFEs managed between 1995 and 2016. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/BPO.0000000000001339DOI Listing
January 2019
13 Reads

SHH pathway inhibition is protumourigenic in adamantinomatous craniopharyngioma.

Endocr Relat Cancer 2019 Jan 1. Epub 2019 Jan 1.

J Martinez-Barbera, Institute of Child Health, Developmental Biology and Cancer Programme Birth Defects Research Centre, University College London, 30 Guilford Street , London, United Kingdom of Great Britain and Northern Ireland.

Pharmacological inhibition of the sonic hedgehog (SHH) pathway can be beneficial against certain cancers but detrimental in others. Adamantinomatous craniopharyngioma (ACP) is a relevant pituitary tumour, affecting children and adults, that is associated with high morbidity and increased mortality in long-term follow up. We have previously demonstrated overactivation of the SHH pathway in both human and mouse ACP. Read More

View Article

Download full-text PDF

Source
https://erc.bioscientifica.com/view/journals/erc/aop/erc-18-
Publisher Site
http://dx.doi.org/10.1530/ERC-18-0538DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378366PMC
January 2019
11 Reads

Long-term impact of pediatric endoscopic endonasal skull base surgery on midface growth.

J Neurosurg Pediatr 2019 01 11:1-8. Epub 2019 Jan 11.

Departments of1Plastic Surgery.

OBJECTIVE Cranial base development plays a large role in anterior and vertical maxillary growth through 7 years of age, and the effect of early endonasal cranial base surgery on midface growth is unknown. The authors present their experience with pediatric endoscopic endonasal surgery (EES) and long-term midface growth. METHODS This is a retrospective review of cases where EES was performed from 2000 to 2016. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3171/2018.8.PEDS18183DOI Listing
January 2019
2 Reads

Management of Craniopharyngioma.

J Craniofac Surg 2019 Jan 10. Epub 2019 Jan 10.

Department of Pathology, Şişli Hamidiye Etfal Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.

Objective: Craniopharyngiomas are one of the most challenging problems for neurosurgeons because of the high recurrence rates due to their localization and associated endocrinological disorders. This study reports the outcomes of surgeries and recurrence rates of 45 craniopharyngioma cases.

Method: Patients who were diagnosed with craniopharyngioma in the authors' clinic between 1998 and 2016 evaluated retrospectively. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/SCS.0000000000005136DOI Listing
January 2019
11 Reads

[Psychosis and behavioural problems as first symptoms of brain tumour?]

Authors:
J Schildermans

Tijdschr Psychiatr 2019;61(1):53-56

A craniopharyngioma is a rare, slow-growing tumour in the pituitary gland. Brain tumours usually present with obvious neurological or other physical symptoms, whereas psychiatric symptoms as primary signs are rare. The presented case, in which psychosis and behavioural problems predominated, concerned a 42-year-old patient. Read More

View Article

Download full-text PDF

Source
January 2019
3 Reads

Supplemental glucocorticoids and anesthesia for noninvasive indications in children with central adrenal insufficiency: A retrospective study.

Paediatr Anaesth 2019 03;29(3):292-294

Department of Radiation Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/pan.13586
Publisher Site
http://dx.doi.org/10.1111/pan.13586DOI Listing
March 2019
17 Reads

Trajectories of psychosocial and cognitive functioning in pediatric patients with brain tumors treated with radiation therapy.

Neuro Oncol 2019 Jan 8. Epub 2019 Jan 8.

Department of Radiation Oncology, St. Jude Children's Research Hospital.

Background: Pediatric patients with brain tumors who are treated with radiation therapy (RT) are at risk for neurocognitive and psychosocial late effects. Research to date has primarily examined these outcomes at a group level and in isolation. Advanced statistical techniques allow for person-centered analyses, as well as examination of relationships between domain-specific trajectories. Read More

View Article

Download full-text PDF

Source
https://academic.oup.com/neuro-oncology/advance-article/doi/
Publisher Site
http://dx.doi.org/10.1093/neuonc/noz010DOI Listing
January 2019
10 Reads

Noninvasive molecular diagnosis of craniopharyngioma with MRI-based radiomics approach.

BMC Neurol 2019 Jan 7;19(1). Epub 2019 Jan 7.

Department of Electronic Engineering, Fudan University, Shanghai, China.

Background: Frequent somatic mutations of BRAF and CTNNB1 were identified in both histological subtypes of craniopharyngioma (adamantinomatous and papillary) which shed light on target therapy to cure this oncogenic disease. The aim of this study was to investigate the noninvasive MRI-based radiomics diagnosis to detect BRAF and CTNNB1 mutations in craniopharyngioma patients.

Methods: Forty-four patients pathologically diagnosed as adamantinomatous craniopharyngioma (ACP) or papillary craniopharyngioma (PCP) were retrospectively studied. Read More

View Article

Download full-text PDF

Source
https://bmcneurol.biomedcentral.com/articles/10.1186/s12883-
Publisher Site
http://dx.doi.org/10.1186/s12883-018-1216-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322318PMC
January 2019
14 Reads

Management of hypothalamic disease in patients with craniopharyngioma.

Clin Endocrinol (Oxf) 2019 Apr 11;90(4):506-516. Epub 2019 Feb 11.

Department of Endocrinology, St Vincent's University Hospital, Dublin, Ireland.

Patients with craniopharyngioma experience excess morbidity and mortality when compared with the background population and with other hypopituitary patients. Large, suprasellar tumours which form micropapillae into surrounding structures can cause hypothalamic damage before any therapeutic intervention; attempted gross total resection can lead to hypothalamic obesity, sleep disorders, thirst disorders and dysregulation of temperature as well as panhypopituitarism. The management of tumour bulk and the pathophysiology of hypothalamic complications have been reviewed extensively. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/cen.13929
Publisher Site
http://dx.doi.org/10.1111/cen.13929DOI Listing
April 2019
4 Reads

Endoscopic Endonasal Surgery for Craniopharyngiomas: A Series of 60 Patients.

World Neurosurg 2019 Jan 3. Epub 2019 Jan 3.

Department of Neurosurgery, First Affiliated Hospital, Chongqing Medical University, Yuzhong District, Chongqing, P.R. China. Electronic address:

Objective: To report our experience of the management of 60 patients with craniopharyngioma with endoscopic endonasal surgery (EES) and evaluate the feasibility and safety of EES for craniopharyngiomas.

Methods: The clinical data of 60 patients with craniopharyngioma who underwent EES between November 2014 and December 2017 were analyzed retrospectively. All patients had vascularized nasoseptal flaps, and the most recent 4 patients had "in situ bone flaps" for better skull base reconstruction. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S18788750183293
Publisher Site
http://dx.doi.org/10.1016/j.wneu.2018.12.110DOI Listing
January 2019
11 Reads

Recurrence of Ventral Skull Base Lesions Attributed to Tumor Seeding: A Systematic Review.

World Neurosurg 2018 Dec 31. Epub 2018 Dec 31.

Department of Otolaryngology, William Beaumont Hospital, Royal Oak, Michigan, USA; Barbara Ann Karmanos Cancer Institute, Detroit, Michigan, USA.

Objective: To evaluate ventral skull base lesion recurrences along surgical access pathways attributed to iatrogenic seeding.

Methods: A systematic review of the literature was performed searching for recurrence of ventral skull base lesions attributed to iatrogenic implantation. Studies were assessed for level of evidence. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S18788750183292
Publisher Site
http://dx.doi.org/10.1016/j.wneu.2018.12.104DOI Listing
December 2018
20 Reads

Stature-weight growth delays: Clinical and etiological aspects.

J Family Med Prim Care 2018 Sep-Oct;7(5):963-966

Department of Endocrinology, Faculty of Medicine and Pharmacy, Ibn Zohr University, Agadir, Morocco.

Background: Stature-weight growth delay (SWGD) is a frequent motivation of consultation. It could be a consequence of a known chronic affection, congenital or acquired affection. The purpose of this study is to describe epidemiological, clinical, paraclinical, and etiological aspects of SWGD. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/jfmpc.jfmpc_207_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259559PMC
January 2019
2 Reads

Craniopharyngiomas and odontogenic tumors mimic normal odontogenesis and share genetic mutations, histopathologic features, and molecular pathways activation.

Oral Surg Oral Med Oral Pathol Oral Radiol 2019 Mar 16;127(3):231-236. Epub 2018 Nov 16.

Department of Oral Surgery and Pathology, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.

Odontogenic tumors bear some histopathologic and molecular resemblance to craniopharyngiomas. Specifically, adamantinomatous craniopharyngioma shares morphologic features and CTNNB1 (the gene encoding β-catenin) mutations with calcifying odontogenic cyst, whereas papillary craniopharyngioma and ameloblastoma are driven by BRAF mutations. Recently, important similarities between adamantinomatous craniopharyngioma and the cell signaling pathways involved in tooth formation have been described. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.oooo.2018.11.004DOI Listing
March 2019
1 Read