336 results match your criteria Cost Effectiveness and Resource Allocation[Journal]


Correction to: Response to: Costs and savings associated with a pharmacists prescribing for minor ailments program in Saskatchewan.

Cost Eff Resour Alloc 2019 29;17. Epub 2019 Jan 29.

1School of Public Health, University of Saskatchewan, Saskatoon, Canada.

[This corrects the article DOI: 10.1186/s12962-018-0159-y.]. Read More

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http://dx.doi.org/10.1186/s12962-019-0170-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352359PMC
January 2019

Willingness to pay for social health insurance and its determinants among public servants in Mekelle City, Northern Ethiopia: a mixed methods study.

Cost Eff Resour Alloc 2019 15;17. Epub 2019 Jan 15.

2School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.

Background: Owing to lack of adequate healthcare financing, access to at least the basic health services is still a problem in Ethiopia. With the intention of raising funds and ensuring universal health coverage, a mandatory health insurance scheme has been introduced. The Community Based Health Insurance has been implemented in all regions of the country, while implementation of social health insurance was delayed mainly due to resistance from public servants. Read More

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http://dx.doi.org/10.1186/s12962-019-0171-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332701PMC
January 2019

Cost-utility analysis of adjuvant imatinib treatment in patients with high risk of recurrence after gastrointestinal stromal tumour (GIST) resection in Thailand.

Cost Eff Resour Alloc 2019 8;17. Epub 2019 Jan 8.

1Health Intervention and Technology Assessment Program (HITAP), Department of Health 6th floor, 6th Building, Ministry of Public Health, Tiwanon Road, Muang, Nonthaburi, 11000 Thailand.

Background: Many patients develop tumour recurrence within a few years after undergoing surgical resection of gastrointestinal stromal tumours (GIST). Adjuvant imatinib treatment is recommended for patients with high risk of GIST recurrence as it can improve recurrence-free survival and overall survival of patients. This study aims to assess the cost-utility of adjuvant imatinib in patients with high risk of GIST recurrence after surgery compared with no adjuvant therapy in Thailand. Read More

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http://dx.doi.org/10.1186/s12962-018-0169-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323771PMC
January 2019
1 Read

Cost-effectiveness of antibiotic prophylaxis in elective cesarean section.

Cost Eff Resour Alloc 2018 18;16:66. Epub 2018 Dec 18.

5University Health Care Research Center, Faculty of Medicine and Health, Örebro University, 701 85 Örebro, Sweden.

Background: The proportion of pregnant women delivered by cesarean section has increased steadily during the past three decades. The risk of infection is 10-fold augmented after elective cesarean section compared to vaginal delivery. Antibiotic prophylaxis may reduce endometritis by 62% and superficial wound infection by 38% after elective cesarean section. Read More

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http://dx.doi.org/10.1186/s12962-018-0168-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299592PMC
December 2018
2 Reads

Medical advice-seeking behaviors based on transaction cost theory.

Cost Eff Resour Alloc 2018 14;16:65. Epub 2018 Dec 14.

No. 3 Keelung Road Sec. 4, Taipei, Taiwan.

Background: Given the global trend of aging societies, medical expenditure has hit record highs in many countries. Because medical advice-seeking behaviors can affect the health of whole societies, how members of a society make medical-related decisions with limited available resources is worthy of investigation. Although transaction cost theory has been extensively applied in commercial research, it is yet to be applied in studies on medical advice-seeking behaviors. Read More

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http://dx.doi.org/10.1186/s12962-018-0167-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295100PMC
December 2018
1 Read

Cost effectiveness of HIV and sexual reproductive health interventions targeting sex workers: a systematic review.

Cost Eff Resour Alloc 2018 4;16:63. Epub 2018 Dec 4.

3Institute for Global Health, University College London, 30 Guilford Street, London, WC1N 1EH UK.

Background: Sex workers have high incidences of HIV and other sexually transmitted diseases. Although, interventions targeting sex workers have shown to be effective, evidence on which strategies are most cost-effective is limited. This study aims to systematically review evidence on the cost-effectiveness of sexual health interventions for sex workers on a global level. Read More

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http://dx.doi.org/10.1186/s12962-018-0165-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278021PMC
December 2018
3 Reads

A comprehensive map of the evidence on the performance evaluation indicators of public hospitals: a scoping study and best fit framework synthesis.

Cost Eff Resour Alloc 2018 6;16:64. Epub 2018 Dec 6.

2Health Services Management, Health Human Resources Research Center, School of Management and Medical Informatics, Shiraz University of Medical Sciences, Shiraz, Iran.

Introduction: Key performance indicators are essential navigation tools for hospitals. They provide managers with valid information enabling them to identify institutional strengths and weaknesses and improve managerial performance. In this study, the synthesis of evidence relating to hospital performance indicators was carried out by means of a field review and the indicators were analyzed through the Best Fit Method. Read More

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http://dx.doi.org/10.1186/s12962-018-0166-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282321PMC
December 2018
1 Read

Cost-effectiveness of a combined intervention of long lasting insecticidal nets and indoor residual spraying compared with each intervention alone for malaria prevention in Ethiopia.

Cost Eff Resour Alloc 2018 22;16:61. Epub 2018 Nov 22.

1Department of Global Public Health and Primary Care, Centre for International Health, University of Bergen, Bergen, Norway.

Background: The effectiveness of long lasting insecticidal nets (LLINs) and indoor residual spraying (IRS), for malaria prevention, have been established in several studies. However, the available evidence about the additional resources required for a combined implementation (LLIN + IRS) with respect to the added protection afforded is limited. Therefore, the aim of this study was to compare the cost-effectiveness of combined implementation of LLINs and IRS, compared with LLINs alone, IRS alone, and routine practice in Ethiopia. Read More

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http://dx.doi.org/10.1186/s12962-018-0164-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251210PMC
November 2018
7 Reads

Costs and savings associated with a pharmacists prescribing for minor ailments program in Saskatchewan.

Cost Eff Resour Alloc 2018 22;16:62. Epub 2018 Nov 22.

1School of Public Health, University of Saskatchewan, Saskatoon, Canada.

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http://dx.doi.org/10.1186/s12962-018-0159-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251156PMC
November 2018
7 Reads

The acceptance and willingness to pay (WTP) for hypothetical dengue vaccine in Penang, Malaysia: a contingent valuation study.

Cost Eff Resour Alloc 2018 22;16:60. Epub 2018 Nov 22.

2Discipline of Social & Administrative Pharmacy, School of Pharmaceutical Sciences, Universiti Sains Malaysia (USM), 11800 Gelugor, Penang Malaysia.

Background: Malaysia has been experiencing an escalation in dengue cases since the past 5 years. As the dengue vaccine pipeline continues to develop steadily with strong public interests, this study had been sought to elicit the acceptance and the willingness to pay (WTP) for hypothetical dengue vaccine in Malaysia.

Methods: This study adopted the cross-sectional, contingent valuation study that involved 400 respondents in Penang, Malaysia. Read More

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http://dx.doi.org/10.1186/s12962-018-0163-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249975PMC
November 2018
2 Reads

Cost-effectiveness of strategies to prevent road traffic injuries in eastern sub-Saharan Africa and Southeast Asia: new results from WHO-CHOICE.

Cost Eff Resour Alloc 2018 20;16:59. Epub 2018 Nov 20.

5Mental Health and Mental Disorders, World Health Organization, Copenhagen, Denmark.

Background: Road safety has been receiving increased attention through the United Nations Decade of Action on Road Safety, and is also now specifically addressed in the sustainable development goals 3.6 and 11.2. Read More

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https://resource-allocation.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s12962-018-0161-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245850PMC
November 2018
8 Reads

Minor ailments, major problems: a critical appraisal of Rafferty et al. (2017).

Authors:
Rudy Zimmer

Cost Eff Resour Alloc 2018 19;16:57. Epub 2018 Nov 19.

Department of Community Health Sciences, The University of Calgary, Calgary, AB Canada.

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http://dx.doi.org/10.1186/s12962-018-0160-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245620PMC
November 2018
7 Reads

Cost-effectiveness analysis of secukinumab versus other biologics and apremilast in the treatment of active Psoriatic arthritis: a Finnish perspective.

Cost Eff Resour Alloc 2018 16;16:56. Epub 2018 Nov 16.

4School of Pharmacy, University of Eastern Finland, Kuopio, Finland.

Objective: To study cost-effectiveness of an interleukin (IL)-17A inhibitor secukinumab, with other biologics and apremilast in patients with Psoriatic arthritis (PsA) from payer perspective in Finland.

Methods: In this semi-Markov model, subcutaneous (SC) secukinumab was compared with SC treatments etanercept and its biosimilar, certolizumab pegol, adalimumab and its biosimilar, golimumab, ustekinumab, intravenous (IV) treatment infliximab, as well as oral non-biologic apremilast. Patients without prior exposure (naïve) to biologics and without moderate to severe psoriasis were considered for secukinumab 150 mg group. Read More

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http://dx.doi.org/10.1186/s12962-018-0162-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240184PMC
November 2018
2 Reads

Impact of drug substitution on cost of care: an example of economic analysis of cetuximab versus panitumumab.

Cost Eff Resour Alloc 2018 12;16:30. Epub 2018 Nov 12.

2Norris Comprehensive Cancer Center, University of Southern California, 1441 Eastlake Ave. Suite 3440, Los Angeles, CA 90033 USA.

Background: The alarming increase in the cost of cancer care is forcing all stakeholders to re-evaluate their approach to treatment. Drugs are the main contributor to the cost. To evaluate the significance of drug substitution on the cost of care we assessed the economic value of panitumumab vs. Read More

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http://dx.doi.org/10.1186/s12962-018-0132-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233290PMC
November 2018
8 Reads

Can reflective multicriteria be the new paradigm for healthcare decision-making? The EVIDEM journey.

Cost Eff Resour Alloc 2018 9;16(Suppl 1):54. Epub 2018 Nov 9.

Montreal, QC Canada.

Background: Multiple technologies, procedures and programs call for fairly-based decisions for prioritization of healthcare interventions. There is a diversity of perspectives of what constitutes a legitimate decision, which depends on both the process and the reasoning applied. Current approaches focus on technical aspects while methods to support alignment of decisions with the compassionate impetus of healthcare systems is lacking. Read More

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http://dx.doi.org/10.1186/s12962-018-0116-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225552PMC
November 2018
5 Reads

Commentary: setting priorities in NCD prevention and control.

Cost Eff Resour Alloc 2018 9;16(Suppl 1):53. Epub 2018 Nov 9.

2Department of Noncommunicable Diseases and Mental Health, Pan American Health Organization, 525 23rd St NW, Washington, DC USA.

Decision making in health requires the use of sound evidence and context-specific information, guided by a priority setting methodology or framework. For noncommunicable disease (NCD) prevention and control, a decision-making methodology has been applied by the World Health Organization to delineate priorities, and options for cost-effective NCD interventions. A set of 14 interventions considered very cost-effective, affordable and feasible for implementation in various resource level settings were identified. Read More

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http://dx.doi.org/10.1186/s12962-018-0133-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225602PMC
November 2018
5 Reads

Priority setting in health: development and application of a multi-criteria algorithm for the population of New Zealand's Waikato region.

Cost Eff Resour Alloc 2018 9;16(Suppl 1):52. Epub 2018 Nov 9.

1Department of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, USA.

Background: Priority setting in a climate of diverse needs and limited resources is one of the most significant challenges faced by health care policymakers. This paper develops and applies a comprehensive multi-criteria algorithm to help determine the relative importance of health conditions that affect a defined population.

Methods: Our algorithm is implemented in the context of the Waikato District Health Board (WDHB) in New Zealand, which serves approximately 10% of the New Zealand population. Read More

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http://dx.doi.org/10.1186/s12962-018-0121-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225550PMC
November 2018
6 Reads

Combining A4R and MCDA in priority setting for health.

Authors:
Norman Daniels

Cost Eff Resour Alloc 2018 9;16(Suppl 1):51. Epub 2018 Nov 9.

Harvard University, Boston, MA USA.

Multiple criteria decision analysis (MCDA) has been proposed as a method for determining the criteria to be used in health technology assessment. A standard criticism of MCDA is that it lacks attention to securing legitimacy for its decisions. The relevance condition of A4R has been criticized for its vagueness because it lacks a focus on criteria selection. Read More

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http://dx.doi.org/10.1186/s12962-018-0124-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225546PMC
November 2018
1 Read

Multi-criteria decision analysis: of politics, policy entrepreneurs, and processes.

Authors:
Victoria Y Fan

Cost Eff Resour Alloc 2018 9;16(Suppl 1):50. Epub 2018 Nov 9.

1Office of Public Health Studies, Myron B. Thompson School of Social Work, University of Hawai'i at Mānoa, 1960 East-West Road, Biomed D204, Honolulu, HI USA.

Multi-criteria decision analysis (MCDA) has the potential to increase the consistency, transparency and rigour with which these criteria inform decisions. Political context is relevant not only as a motivation for turning to MCDA but also the context in which MCDA can be successfully implemented. A policy entrepreneur can spearhead the creation of a process to carry out MCDA and can help to create and build the capacity of a public institution that observes and convenes this process, an institution that has legal authority to carry out such a function. Read More

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https://resource-allocation.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s12962-018-0131-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225609PMC
November 2018
8 Reads

Introduction: priority setting in global health.

Cost Eff Resour Alloc 2018 9;16(Suppl 1):49. Epub 2018 Nov 9.

Department of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, USA.

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http://dx.doi.org/10.1186/s12962-018-0115-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225612PMC
November 2018
1 Read

Resource allocation in decision support frameworks.

Cost Eff Resour Alloc 2018 9;16(Suppl 1):48. Epub 2018 Nov 9.

2National Academies of Science, Engineering and Medicine, Washington, DC USA.

Background: Cost-benefit and cost-effectiveness analysis place limits on the dimensions of value that the models can incorporate. Cost-benefit analysis requires monetization of all measures of value (including life), a task sometimes deemed either difficult to accomplish or even repugnant. Cost-effectiveness analyses include health care gains in natural units (e. Read More

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https://resource-allocation.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s12962-018-0128-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225606PMC
November 2018
8 Reads

HTA and MCDA solely or combined? The case of priority-setting in Colombia.

Cost Eff Resour Alloc 2018 9;16(Suppl 1):47. Epub 2018 Nov 9.

2Ministry of Health and Social Protection, Bogotá, Colombia.

Background: All healthcare systems face problems of justice and efficiency related to setting priorities for allocating limited financial resources. Therefore, explicit decision-making in healthcare depicted as a continuum from evidence generation to deliberation and communication of the decision made, needs to be transparent and fair. Nevertheless, priority-setting in many parts of the world remains being implicit and ad-hoc process. Read More

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http://dx.doi.org/10.1186/s12962-018-0127-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225554PMC
November 2018
13 Reads

Setting health sector priorities: a brief overview of Ethiopia's experience.

Cost Eff Resour Alloc 2018 9;16(Suppl 1):46. Epub 2018 Nov 9.

1Federal Ministry of Health, Addis Ababa, Ethiopia.

As a country with significant resource constraints, a fair and efficient health priority setting should be at the cornerstone of Ethiopia's commitment to attain universal health coverage by 2035. This paper draws on the current national strategies including the national essential health service package to explore the criteria and processes used to set the existing national health sector priorities. Additionally, it reviews Ethiopia's experience in comparison with the multi-criteria decision analysis proposed by Baltussen et al. Read More

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http://dx.doi.org/10.1186/s12962-018-0117-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225615PMC
November 2018
11 Reads

MCDA from a health economics perspective: opportunities and pitfalls of extending economic evaluation to incorporate broader outcomes.

Authors:
Mark Jit

Cost Eff Resour Alloc 2018 9;16(Suppl 1):45. Epub 2018 Nov 9.

1Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT UK.

Background: Multi-criteria decision analysis (MCDA) is a structured decision-making process that offers greater flexibility to incorporate multiple objectives than cost-effectiveness analysis or benefit-cost analysis.

Conclusions: The flexibility of MCDA requires careful consideration of its methodological underpinnings, analytical forms and cognitive biases that may arise in eliciting trade-off. The methodology of MCDA should ideally incorporate both deliberative and technical processes. Read More

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http://dx.doi.org/10.1186/s12962-018-0118-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225613PMC
November 2018
1 Read

How can MCDA tools improve priority setting? Four critical questions.

Authors:
Ole F Norheim

Cost Eff Resour Alloc 2018 9;16(Suppl 1):44. Epub 2018 Nov 9.

1Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.

This comment argues that four critical questions needs to be resolved before MCDA tools can improve priority setting in health: how to merge the quantitative and deliberative elements of MCDA; how to select criteria; how to weigh them, and whom to bring to the table. Read More

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http://dx.doi.org/10.1186/s12962-018-0119-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225650PMC
November 2018
4 Reads

Incorporating MCDA into HTA: challenges and potential solutions, with a focus on lower income settings.

Cost Eff Resour Alloc 2018 9;16(Suppl 1):43. Epub 2018 Nov 9.

4School of Public Health, Imperial College, London, UK.

Background: Multicriteria decision analysis (MCDA) has the potential to bring more structure and transparency to health technology assessment (HTA). The objective of this paper is to highlight key methodological and practical challenges facing the use of MCDA for HTA, with a particular focus on lower and middle-income countries (LMICs), and to highlight potential solutions to these challenges.

Methodological Challenges: Key lessons from existing applications of MCDA to HTA are summarized, including: that the socio-technical design of the MCDA reflect the local decision problem; the criteria set properties of additive models are understood and applied; and the alternative approaches for estimating opportunity cost, and the challenges with these approaches are understood. Read More

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http://dx.doi.org/10.1186/s12962-018-0125-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225551PMC
November 2018
1 Read

Priority setting for the introduction of rotavirus vaccine: what evidence was essential?

Authors:
Roger I Glass

Cost Eff Resour Alloc 2018 9;16(Suppl 1):42. Epub 2018 Nov 9.

Fogarty International Center, National Institutes of Health, 31 Center Drive, MSC 2220, Bethesda, MD 20892 USA.

Rotavirus (RV) diarrhea is the most common cause of severe diarrhea in children worldwide and since 2006, vaccines have been available and recommended by WHO for use in all children. We developed protocols that countries could use to assess the burden of RV disease in their own countries and the cost-effectiveness of a program for vaccine introduction. A decade later and in the setting of extreme tiering of prices so that the poorest countries pay the least for the vaccine, more than 92 countries have introduced this vaccine into their national programs and more than 90 have not. Read More

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http://dx.doi.org/10.1186/s12962-018-0126-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225549PMC
November 2018
13 Reads

MCDA or preference-based social welfare functions?

Authors:
J P Sevilla

Cost Eff Resour Alloc 2018 9;16(Suppl 1):41. Epub 2018 Nov 9.

Data for Decisions, LLC, Waltham, MA USA.

Preference-based social welfare functions (pbSWF) perform better at reconciling competing personal and social goals than typical forms of MCDA. Its virtues are (a) its respect for people's own judgments about the relative values of health, wealth, and other broad benefits within their lives (non-paternalism) and (b) its conformity with reasonable ethical axioms. Any discrepancy between an MCDA objective function and that implied by pbSWF suggests the former's failure to respect non-paternalism and reasonable ethical principles. Read More

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http://dx.doi.org/10.1186/s12962-018-0122-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225614PMC
November 2018
2 Reads

Panel discussion on the application of MCDA tools.

Authors:
Michael Watson

Cost Eff Resour Alloc 2018 9;16(Suppl 1):40. Epub 2018 Nov 9.

Moderna Therapeutics, Cambridge, MA USA.

Prioritization in healthcare is particularly sensitive to subjective biases and data asymmetry. Yet making data-based and objective decisions are critical to optimizing long term individual and societal benefit. Multi-Criteria-Decision-Making-Analysis (MCDA) provides shared processes, structure, and language to enable this. Read More

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http://dx.doi.org/10.1186/s12962-018-0130-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225553PMC
November 2018
1 Read

Including the public perspective in health-related MCDA: ideas from the field of public opinion research and polling.

Cost Eff Resour Alloc 2018 9;16(Suppl 1):39. Epub 2018 Nov 9.

Harvard Opinion Research Program, Department of Health Policy and Management, Harvard T.H. Chan School of Public Health, 677 Huntington Avenue, Boston, MA 0211 USA.

This commentary utilizes the lens of public opinion research in health to suggest ideas for best integrating public input into multi-criteria decisions analysis (MCDA) approaches. The field of public opinion research suggests: (1) there is frequently a distinction between public and expert views, even outside of situations where the public has direct experience; (2) representative samples are important to ensure findings reflect all segments of the relevant population; and (3) limiting cognitive burden in studies designed to elicit public preferences is essential for meaningful responses that represent the population's views. Together these reflections suggest the need for considering new avenues for including public views in MCDA approaches where representative samples relying on well-designed questions are utilized more regularly. Read More

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http://dx.doi.org/10.1186/s12962-018-0123-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225607PMC
November 2018
7 Reads

Stakeholder involvement in Multi-Criteria Decision Analysis.

Cost Eff Resour Alloc 2018 9;16(Suppl 1). Epub 2018 Nov 9.

2National Academies of Sciences Engineering, and Medicine, Washington, DC USA.

This brief perspective highlights the importance of decision maker buy-in and ownership through stakeholder engagement in the co-construction of the multi-criteria decision analysis (MCDA) model. A brief historical overview of MCDA is presented before outlining the importance of bridging the gap (and to gain trust) between the tool developers and users. The issues with the current MCDA tool development and testing efforts are highlighted, and the ownership and routine adoption of the MCDA process is discussed. Read More

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http://dx.doi.org/10.1186/s12962-018-0120-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225647PMC
November 2018
1 Read

Cost-effective interventions for breast cancer, cervical cancer, and colorectal cancer: new results from WHO-CHOICE.

Cost Eff Resour Alloc 2018 29;16:38. Epub 2018 Oct 29.

5Health Systems Governance and Financing, World Health Organization, Avenue Appia 20, Geneva, Switzerland.

Background: Following the adoption of the Global Action Plan for the Prevention and Control of NCDs 2013-2020, an update to the Appendix 3 of the action plan was requested by Member States in 2016, endorsed by the Seventieth World Health Assembly in May 2017 and provides a list of recommended NCD interventions. The main contribution of this paper is to present results of analyses identifying how decision makers can achieve maximum health gain using the cancer interventions listed in the Appendix 3. We also present methods used to calculate new WHO-CHOICE cost-effectiveness results for breast cancer, cervical cancer, and colorectal cancer in Southeast Asia and eastern sub-Saharan Africa. Read More

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http://dx.doi.org/10.1186/s12962-018-0157-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206923PMC
October 2018
7 Reads

Comparative cost-effectiveness of surgery, angioplasty, or medical therapy in patients with multivessel coronary artery disease: MASS II trial.

Cost Eff Resour Alloc 2018 3;16:55. Epub 2018 Nov 3.

1Instituto do Coração (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, Av Dr Eneas de Carvalho Aguiar 44 - Cerqueira Cesar, São Paulo, SP CEP 05403-000 Brazil.

Background: The costs for treating coronary artery disease (CAD) are high worldwide. We performed a prespecified analyses of cost-effectiveness of three therapeutic strategies for multivessel CAD.

Methods: From May 1995 to May 2000, a total of 611 patients were randomly assigned to coronary artery bypass graft (CABG), n = 203; percutaneous coronary intervention (PCI), n = 205; or medical treatment (MT), n = 203. Read More

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http://dx.doi.org/10.1186/s12962-018-0158-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215652PMC
November 2018
10 Reads

The role of management on costs and efficiency in HIV prevention interventions for female sex workers in Nigeria: a cluster-randomized control trial.

Cost Eff Resour Alloc 2018 23;16:37. Epub 2018 Oct 23.

5National Agency for the Control of AIDS (NACA), Abuja, Nigeria.

Background: While the world has made much global progress toward the reduction of new HIV infections, HIV continues to be an important public health problem. In the face of constantly constrained resources, donors and grantees alike must seek to optimize resources and deliver HIV services as efficiently as possible. While there is evidence that management practices can affect efficiency, this has yet to be rigorously tested in the context of HIV service delivery. Read More

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http://dx.doi.org/10.1186/s12962-018-0107-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199740PMC
October 2018
3 Reads

Using a dynamic adherence Markov model to assess the efficiency of Respiratory Medication Therapy Adherence Clinic (RMTAC) on asthma patients in Malaysia.

Cost Eff Resour Alloc 2018 19;16:36. Epub 2018 Oct 19.

2Discipline of Social & Administrative Pharmacy, School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800 Penang, Malaysia.

Background: Respiratory Medication Therapy Adherence Clinic (RMTAC) is an initiative by the Ministry of Health (MOH) Malaysia to improve patients' medication adherence, as an adjunct to the usual physician care (UC). This study aimed to evaluate the cost-effectiveness of combined strategy of RMTAC and UC (RMTAC + UC) vs. UC alone in asthma patients, from the MOH Malaysia perspective. Read More

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https://resource-allocation.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s12962-018-0156-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195711PMC
October 2018
5 Reads

National cost study versus hospital cost accounting for organ recovery cost assessment in a French hospital group.

Cost Eff Resour Alloc 2018 11;16:34. Epub 2018 Oct 11.

1Pôle de Santé Publique, Service d'Evaluation Economique en Santé, Hospices Civils de Lyon, 162, Avenue Lacassagne - Bâtiment A, 69424 Lyon Cedex 03, France.

Background: The choice of cost data sources is crucial, because it influences the results of cost studies, decisions of hospital managers and ultimately national directives of policy makers. The main objective of this study was to compare a hospital cost accounting system in a French hospital group and the national cost study (ENC) considering the cost of organ recovery procedures. The secondary objective was to compare these approaches to the weighting method used in the ENC to assess organ recovery costs. Read More

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https://resource-allocation.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s12962-018-0155-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190563PMC
October 2018
11 Reads

A pilot study on patient-related costs and factors associated with the cost of specialist palliative care in the hospital: first steps towards a patient classification system in Germany.

Cost Eff Resour Alloc 2018 16;16:35. Epub 2018 Oct 16.

Department of Palliative Medicine, University Hospital, Ludwig-Maximilians-Universität München, Munich, Germany.

Background: Specialist palliative care in the hospital addresses a heterogeneous patient population with complex care needs. In Germany, palliative care patients are classified based on their primary diagnosis to determine reimbursement despite findings that other factors describe patient needs better. To facilitate adequate resource allocation in this setting, in Australia and in the UK important steps have been undertaken towards identifying drivers of palliative care resource use and classifying patients accordingly. Read More

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http://dx.doi.org/10.1186/s12962-018-0154-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192371PMC
October 2018
1 Read

Cost-effectiveness analysis for midostaurin versus standard of care in acute myeloid leukemia in the United Kingdom.

Cost Eff Resour Alloc 2018 4;16:33. Epub 2018 Oct 4.

Purple Squirrel Economics, 4 Lexington Avenue, Suite 15K, New York, NY 10010 USA.

Aims: Midostaurin (MIDO) has been proposed for the treatment of newly-diagnosed adult patients with FMS-like tyrosine kinase 3 mutation-positive (FLT3+) acute myeloid leukemia (AML) in combination with standard chemotherapy. The cost-effectiveness of MIDO and standard of care (SOC) followed by MIDO monotherapy was compared to SOC alone for newly-diagnosed FLT3+ AML in the UK.

Methods: A partitioned survival model was developed from a UK public healthcare system perspective to compare the cost-effectiveness of MIDO plus SOC and SOC over a lifetime horizon. Read More

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https://resource-allocation.biomedcentral.com/articles/10.11
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http://dx.doi.org/10.1186/s12962-018-0153-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172753PMC
October 2018
4 Reads

Budget impact analysis of the adoption of new hypertension guidelines in Colombia.

Cost Eff Resour Alloc 2018 25;16:32. Epub 2018 Sep 25.

1Facultad de Ciencias de la Salud, Universidad Icesi, Calle 18 #122-135, Cali, Valle del Cauca Colombia.

Background: Hypertension represents a high burden of disease in different healthcare systems. Recent guideline published in 2017 by the American Heart Association and the American College of Cardiology has generated a debate between clinicians and policymakers due to the lowering of diagnosis threshold and the subsequent increase of the prevalence and healthcare costs. No empirical research exists addressing the question about the pressure on healthcare costs generated by new standards. Read More

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http://dx.doi.org/10.1186/s12962-018-0152-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157055PMC
September 2018
1 Read

Evaluating the health system financing of the Eastern Mediterranean Region (EMR) countries using Grey Relation Analysis and Shannon Entropy.

Cost Eff Resour Alloc 2018 17;16:31. Epub 2018 Sep 17.

4Health Human Resources Research Center, School of Management and Medical Informatics, Shiraz University of Medical Sciences, Shiraz, Iran.

Background: Sufficient and sustainable financing of the health system is essential for improving the health of the community. The health systems financing of the EMR countries is facing the challenge. Assessment and ranking of healthcare financing can help identify and resolve some challenges of health systems. Read More

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http://dx.doi.org/10.1186/s12962-018-0151-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142403PMC
September 2018
1 Read

Cost-effectiveness of ustekinumab in moderate to severe Crohn's disease in Sweden.

Cost Eff Resour Alloc 2018 2;16:28. Epub 2018 Aug 2.

Quantify Research AB, Stockholm, Sweden.

Background: Human monoclonal antibody ustekinumab is a novel Crohn's disease (CD) treatment blocking pro-inflammatory cytokines interleukin-12 and 23. The study's objective was to assess cost-effectiveness of ustekinumab in moderate to severely active CD in Sweden.

Methods: A cost-effectiveness model with an induction phase decision-tree structure and a maintenance phase Markov cohort structure was constructed. Read More

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http://dx.doi.org/10.1186/s12962-018-0114-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090969PMC
August 2018
19 Reads

Cost-effectiveness analysis of FOLFOX4 and sorafenib for the treatment of advanced hepatocellular carcinoma in China.

Cost Eff Resour Alloc 2018 4;16:29. Epub 2018 Aug 4.

6Department of Medical Oncology, Peking University Cancer Hospital, Peking University International Hospital, No. 1 Life Garden Road, Zhongguancun Life Science Park, Changping District, Beijing, 102206 China.

Objectives: Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths globally. In China, sorafenib and oxaliplatin plus infusional-fluorouracil/leucovorin (FOLFOX4) are approved for the systemic treatment of advanced HCC. This study compared the cost-effectiveness of these therapies from a healthcare system perspective and a patient perspectives. Read More

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http://dx.doi.org/10.1186/s12962-018-0112-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076412PMC
August 2018
4 Reads

Empirical estimation of resource constraints for use in model-based economic evaluation: an example of TB services in South Africa.

Cost Eff Resour Alloc 2018 30;16:27. Epub 2018 Jul 30.

1Department of Global Health and Development, London School of Hygiene & Tropical Medicine, 15-17 Tavistock Place, London, WC1H 9SH UK.

Background: Evidence on the relative costs and effects of interventions that do not consider 'real-world' constraints on implementation may be misleading. However, in many low- and middle-income countries, time and data scarcity mean that incorporating health system constraints in priority setting can be challenging.

Methods: We developed a 'proof of concept' method to empirically estimate health system constraints for inclusion in model-based economic evaluations, using intensified case-finding strategies (ICF) for tuberculosis (TB) in South Africa as an example. Read More

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https://resource-allocation.biomedcentral.com/articles/10.11
Publisher Site
http://dx.doi.org/10.1186/s12962-018-0113-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065151PMC
July 2018
8 Reads

Catastrophic expenditures and impoverishment due to out-of-pocket health payments in Kosovo.

Cost Eff Resour Alloc 2018 28;16:26. Epub 2018 Jul 28.

1Center for International Health at Ludwig-Maximilians-Universität München, Leopoldstr. 7, 80802 Munich, Germany.

Background: The current health system reforms in Kosovo aim to improve health status through universal health coverage. Risk pooling and ensuring access to necessary care without financial hardship are envisaged through compulsory health insurance. We measure the level of financial risk protection through two commonly applied concepts: catastrophic health expenditures and impoverishment. Read More

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http://dx.doi.org/10.1186/s12962-018-0111-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064180PMC
July 2018
5 Reads

Cost effectiveness of mHealth intervention by community health workers for reducing maternal and newborn mortality in rural Uttar Pradesh, India.

Cost Eff Resour Alloc 2018 25;16:25. Epub 2018 Jun 25.

School of Public Health, Post Graduate Institute of Medical Education and Research, Sector-12, Chandigarh, 160012 India.

Background: A variety of mobile-based health technologies (mHealth) have been developed for use by community health workers to augment their performance. One such mHealth intervention-ReMiND program, was implemented in a poor performing district of India. Despite some research on the extent of its effectiveness, there is significant dearth of evidence on cost-effectiveness of such mHealth interventions. Read More

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http://dx.doi.org/10.1186/s12962-018-0110-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020234PMC
June 2018
8 Reads

Primary and secondary prevention interventions for cardiovascular disease in low-income and middle-income countries: a systematic review of economic evaluations.

Cost Eff Resour Alloc 2018 14;16:22. Epub 2018 Jun 14.

1Faculty of Medicine, School of Public Health, The University of Queensland, Brisbane, QLD 4006 Australia.

Background: Cardiovascular disease (CVD) is the leading cause of deaths globally, with greatest premature mortality in the low- and middle-income countries (LMIC). Many of these countries, especially in sub-Saharan Africa, have significant budget constraints. The need for current evidence on which interventions offer good value for money to stem this CVD epidemic motivates this study. Read More

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http://dx.doi.org/10.1186/s12962-018-0108-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003072PMC
June 2018
7 Reads

Cost-effectiveness of diagnostic tests for threatened preterm labor in singleton pregnancy in France.

Cost Eff Resour Alloc 2018 14;16:21. Epub 2018 Jun 14.

Clinical Epidemiology Unit, Inserm, CIC 1432, Dijon, France.

Background: Previous studies have showed that the early diagnosis of threatened preterm labor decreases neonatal morbidity and mortality, avoids maternal morbidity induced by antepartum bed rest and unnecessary treatment, and reduces costs. Although there are many diagnostic tests, none is clearly recommended by international guidelines. The aim of our study was to compare seven diagnostic methods in terms of effectiveness and cost using a decision analysis model in singleton pregnancy presenting threatened preterm labor, between 24 and 34 weeks of gestation. Read More

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http://dx.doi.org/10.1186/s12962-018-0106-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003030PMC
June 2018
8 Reads

Cost-effectiveness of colorectal cancer screening in Ukraine.

Cost Eff Resour Alloc 2018 7;16:20. Epub 2018 Jun 7.

6Tufts Medical Center and Tufts University School of Medicine Boston, Boston, MA USA.

Background: Colorectal cancer is one of the most common cancers worldwide and is associated with high mortality when detected at a later stage. There is a paucity of studies from low and middle income countries to support the cost-effectiveness of colorectal cancer screening. We aim to analyze the cost-effectiveness of colorectal cancer screening compared to no screening in Ukraine, a lower-middle income country. Read More

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http://dx.doi.org/10.1186/s12962-018-0104-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992826PMC
June 2018
3 Reads

Brief interventions to address substance use among patients presenting to emergency departments in resource poor settings: a cost-effectiveness analysis.

Cost Eff Resour Alloc 2018 18;16:24. Epub 2018 Jun 18.

1Health Economics Unit, School of Public Health and Family Medicine, Faculty of Health Sciences, University of Cape Town, Observatory, Cape Town, 7925 South Africa.

Background: There are limited data describing the cost-effectiveness of brief interventions for substance use in resource-poor settings. Using a patient and provider perspective, this study investigates the cost-effectiveness of a brief motivational interviewing (MI) intervention versus a combined intervention of MI and problem solving therapy (MI-PST) for reducing substance use among patients presenting to emergency departments, in comparison to a control group.

Methods: Effectiveness data were extracted from Project STRIVE (Substance use and Trauma InterVention) conducted in South Africa. Read More

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http://dx.doi.org/10.1186/s12962-018-0109-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006568PMC
June 2018
5 Reads

The early economic evaluation of novel biomarkers to accelerate their translation into clinical applications.

Cost Eff Resour Alloc 2018 18;16:23. Epub 2018 Jun 18.

Department of Epidemiology, University of Groningen, University Medical Center Groningen, PO Box 30.001, 9700 RB Groningen, The Netherlands.

Background: Translating prognostic and diagnostic biomarker candidates into clinical applications takes time, is very costly, and many candidates fail. It is therefore crucial to be able to select those biomarker candidates that have the highest chance of successfully being adopted in the clinic. This requires an early estimate of the potential clinical impact and commercial value. Read More

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http://dx.doi.org/10.1186/s12962-018-0105-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6006586PMC
June 2018
11 Reads