61,532 results match your criteria Cosmetics


Chemical characterization of leaves, male and female flowers from spontaneous cannabis (Cannabis sativa var. spontanea) growing in Hungary.

Chem Biodivers 2018 Dec 13. Epub 2018 Dec 13.

University of Camerino, School of Pharmacy, Via Sant'Agostino 1, 62032, Camerino, ITALY.

Cannabis sativa var. spontanea is a spontaneous form of hemp with a low content of psychoactive cannabinoids and can be considered as a valuable source of other phytoconstituents to be used in nutraceuticals or for their health promoting properties. Chemical data on this hemp variety are rather scarce. Read More

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December 2018

Non-endogenous ketocarotenoids accumulation in engineered Synechocystis sp. PCC 6803.

Physiol Plant 2018 Dec 11. Epub 2018 Dec 11.

Istituto di Biologia e Biotecnologia Agraria, Consiglio Nazionale delle Ricerche, Via Bassini 15a 20133, Milano, Italy.

The cyanobacterium Synechocystis sp. PCC 6803 is a model species commonly employed for biotechnological applications. It is naturally able to accumulate zeaxanthin and echinenone, but not astaxanthin, which is the highest value carotenoid produced by microalgae, with a wide range of applications in pharmaceutical, cosmetics, food and feed industries. Read More

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December 2018

Concurrent chemoradiotherapy by simultaneously integrated boost volumetric-modulated arc therapy for nasopharyngeal carcinoma-toxicity/quality of life and survival.

Head Neck 2018 Dec 10. Epub 2018 Dec 10.

Department of Cosmetics and Fashion Styling, Center of Environmental Roxi and Emerging-Contaminant Research, Cheng Shiu University, Kaohsiung, Taiwan.

Background: To investigate the toxicity, changes of quality of life (QOL), and survival for patients with nasopharyngeal cancer (NPC) treated by concurrent chemoradiotherapy (CCRT) with simultaneously integrated boost volumetric-modulated arc therapy (SIB-VMAT).

Methods: A total of 68 NPC patients treated by CCRT with SIB-VMAT technique were collected. QOL was longitudinally assessed by the EORTC QLQ-C30 and HN35 questionnaires at the 4 time points: baseline, 42. Read More

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December 2018

Mercury Contamination of Skin-whitening Creams in Phnom Penh, Cambodia.

J Health Pollut 2015 Dec 21;5(9):33-46. Epub 2015 Dec 21.

University of Wisconsin, Parkside, USA.

Background: In Cambodia, there is widespread use of skin-whitening creams containing levels of mercury that exceed Association of Southeast Asian Nations (ASEAN) guidelines by up to 35,000 times. Mercury in skin-whitening creams threatens to compromise the health of Cambodians.

Objectives: It is important to provide essential information on sources of mercury so that Cambodians can avoid exposure to elevated levels of mercury and to support informed management of consumer goods. Read More

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December 2015

Sources of Mercury Exposure to Children in Low- and Middle-Income Countries.

J Health Pollut 2015 Jun 2;5(8):33-51. Epub 2015 Jul 2.

Civil and Environmental Engineering, Department, U.C.L.A., Los Angeles, CA, U.S.A.

Background: Many children in low- and middle-income countries face enhanced risks of exposure to contaminants via the environment, parental occupation, and other routes. While mercury (Hg) is a global pollutant whose transport properties allow it to have an impact even in pristine areas, the presence of significant Hg sources in the developing world can cause localized effects that are more severe than those observed in other areas.

Objectives: This paper provides a narrative review of sources of Hg exposure to people in the developing world with a particular focus on children, and presents an overview of key aspects to this important issue. Read More

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The Overview of Methods of Nanoparticle Exposure Assessment.

Methods Mol Biol 2019 ;1894:353-367

Key Laboratory of Occupational Safety and Health, Beijing Municipal Institute of Labour Protection, Beijing, People's Republic of China.

Nanotechnology is now widely used in industry as well as consumer products, such as electrical devices, cosmetics, medicine, and household appliances. In the life cycle of the nano-products, including production, use, and disposal, nanoparticles may be released to the environment. However, there is no current consensus on the best method for evaluating and characterizing nanoparticle exposure. Read More

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January 2019
2 Reads

Virus-like particles (VLP) in prophylaxis and immunotherapy of allergic diseases.

Allergo J Int 2018 9;27(8):245-255. Epub 2018 Jul 9.

9Jenner Institute, University of Oxford, Oxford, UK.

Background: Apart from active allergen avoidance, immunotherapy is regarded as the most effective form of treatment available for type I allergies. Such treatments involve the administration of allergen preparations in various forms and by various routes. Virus-like particles (VLPs) offer a very effective platform for immunization with the allergen and are characterized by high immunogenicity, low allergenicity and high clinical efficacy. Read More

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Comparative Chemical Profiles of Essential Oils and Hydrolate Extracts from Fresh Flowers of Eight Paeonia suffruticosa Andr. Cultivars from Central China.

Molecules 2018 Dec 10;23(12). Epub 2018 Dec 10.

Department of Pharmaceutical Sciences, Medical College, Henan University of Science and Technology, Luoyang 471023, China.

Andr. is a famous ornamental and aromatic plant with hundreds of cultivars in China. The objective of this work was to investigate comparative chemical profiles of essential oils and hydrolate extracts from eight . Read More

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December 2018

Investigation of Different Iontophoretic Currents Profiles for Short-Term Applications in Cosmetics.

Pharmaceutics 2018 Dec 7;10(4). Epub 2018 Dec 7.

Instrumental Cosmetics, Applied Research, L'Oréal, 94550 Chevilly-Larue, France.

This study aimed at investigating the effect of electrical current profile upon the iontophoretic transport of (i) ascorbic acid (AA) and (ii) ellagic acid (EA), into porcine skin in vitro, and the impact of the physicochemical properties of both actives on their mechanism of transport when formulated in cosmetic compositions. The experiments were performed using a proprietary iontophoretic device containing a roller to apply the formulation. Three current profiles were tested: (i) galvanic direct current (DC), (ii) square unipolar pulse current (SPC), and (iii) galvanic direct current (DC) + pulse current (PC). Read More

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December 2018

Efficient biosynthesis of low-molecular-weight poly-γ-glutamic acid by stable overexpression of PgdS hydrolase in Bacillus amyloliquefaciens NB.

J Agric Food Chem 2018 Dec 13. Epub 2018 Dec 13.

Low-molecular-weight poly-γ-glutamic acid (LMW-γ-PGA) has attracted much attention owing to its great potential in food, agriculture, medicine and cosmetics. Current methods of LMW-γ-PGA production, including enzymatic hydrolysis, are associated with low operational stability. Here, an efficient method for stable biosynthesis of LMW-γ-PGA was conceived by overexpression of γ-PGA hydrolase in Bacillus amyloliquefaciens NB. Read More

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December 2018

Scalable biosynthesis of melanin by the basidiomycete Armillaria cepistipes.

J Agric Food Chem 2018 Dec 12. Epub 2018 Dec 12.

Natural melanin features many interesting properties, including the ability to shield electromagnetic radiation, to act as scavenger for radical and reactive oxygen species and the capacity to chelate different metal ions. For these reasons, melanin is becoming increasingly relevant for the development of functional materials, for potential applications such as cosmetics, drug delivery and water purification. However, the extraction and purification of melanin from conventional sources (e. Read More

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December 2018

Structure-based design of agarase AgWH50C from Agarivorans gilvus WH0801 to enhance thermostability.

Appl Microbiol Biotechnol 2018 Dec 6. Epub 2018 Dec 6.

College of Food Science and Engineering, Ocean University of China, Qingdao, 266003, China.

AgWH50C, an exo-β-agarase of GH50 isolated from Agarivorans gilvus WH0801, plays a key role in the enzymatic production of neoagarobiose, which has great application prospect in the cosmetics and pharmaceutical industry. In contrast, the poor thermostability becomes the main obstructive factor of glycoside hydrolase (GH) family 50 agarases, including AgWH50C. Herein, based on the AgWH50C crystal structure, we designed several mutants by a multiple cross-linked rational design protocol used thermostability predicting softwares ETSS, PoPMuSiC, and HotMuSiC. Read More

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December 2018

Kojic acid applications in cosmetic and pharmaceutical preparations.

Biomed Pharmacother 2018 Dec 8;110:582-593. Epub 2018 Dec 8.

Student Research Committee, Department of Pharmaceutics, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran. Electronic address:

Skin color disorders can be caused by various factors, such as excessive exposure to sunlight, aging and hormonal imbalance during pregnancy, or taking some medications. Kojic acid (KA) is a natural metabolite produced by fungi that has the ability to inhibit tyrosinase activity in synthesis of melanin. The major applications of KA and its derivatives in medicine are based on their biocompatibility, antimicrobial and antiviral, antitumor, antidiabetic, anticancer, anti-speck, anti-parasitic, and pesticidal and insecticidal properties. Read More

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December 2018
5 Reads

Effects of Angelica gigas Nakai on the production of decursin- and decursinol angelate-enriched eggs.

J Sci Food Agric 2018 Dec 7. Epub 2018 Dec 7.

Institute of Green-Bio Science and Technology, Seoul National University, Pyeongchang-gun, Gangwon-do 25354, Korea.

Background: The livestock industry requires high-quality products as well as improved productivity. There have been many studies regarding the utilization of feed additives to increase productivity, enhance immune functions, and prevent infectious diseases in livestock. Biofunctional feed additives would be beneficial not only for animal health, but also for consumers. Read More

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December 2018
2 Reads

Triclosan Impairs Hippocampal Synaptic Plasticity and Spatial Memory in Male Rats.

Front Mol Neurosci 2018 26;11:429. Epub 2018 Nov 26.

Physiology and Biophysics Program, ICBM, Faculty of Medicine, Universidad de Chile, Santiago, Chile.

Triclosan, a widely used industrial and household agent, is present as an antiseptic ingredient in numerous products of everyday use, such as toothpaste, cosmetics, kitchenware, and toys. Previous studies have shown that human brain and animal tissues contain triclosan, which has been found also as a contaminant of water and soil. Triclosan disrupts heart and skeletal muscle Ca signaling, damages liver function, alters gut microbiota, causes colonic inflammation, and promotes apoptosis in cultured neocortical neurons and neural stem cells. Read More

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November 2018

Analysis of the GC-MS of volatile compounds and the phytochemical profile and antioxidant activities of some Bulgarian medicinal plants.

Z Naturforsch C 2018 Dec 8. Epub 2018 Dec 8.

Department of Catering and Tourism, University of Food Technologies, Plovdiv, Bulgaria.

The study's objective was to investigate the volatile compounds, assess the total phenolic content and phenolic acids profile, determine the antioxidant capacity and evaluate the anthocyanin and flavonoid contents in stinging nettle (Urtica dioica L.), tansy (Tanacetum vulgare L.), bladder campion (Silene vulgaris (Moench) Garcke) and rosehip fruit (Rosa canina L. Read More

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December 2018

Exposure to selected preservatives in personal care products: case study comparison of exposure models and observational biomonitoring data.

J Expo Sci Environ Epidemiol 2018 Dec 5. Epub 2018 Dec 5.

Summit Toxicology, LLP, Bozeman, MT, USA.

Exposure models provide critical information for risk assessment of personal care product ingredients, but there have been limited opportunities to compare exposure model predictions to observational exposure data. Urinary excretion data from a biomonitoring study in eight individuals were used to estimate minimum absorbed doses for triclosan and methyl-, ethyl-, and n-propyl- parabens (TCS, MP, EP, PP). Three screening exposure models (European Commission Scientific Commission on Consumer Safety [SCCS] algorithms, ConsExpo in deterministic mode, and RAIDAR-ICE) and two higher-tier probabilistic models (SHEDS-HT, and Creme Care & Cosmetics) were used to model participant exposures. Read More

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December 2018
1 Read

Purification, characterization, antioxidant and moisture-preserving activities of polysaccharides from Rosa rugosa petals.

Int J Biol Macromol 2018 Nov 30;124:938-945. Epub 2018 Nov 30.

College of Pharmacology, Mudanjiang Medical University, Mudanjiang 157011, PR China. Electronic address:

The present study, we prepared polysaccharides from Rosa rugosa petals (RRPS) using hot-water extraction and purified the polysaccharides by chromatography to obtain RRPS-1 and RRPS-2. Preliminary structural features of RRPS were characterized by different instrumental methods, such as HPGPC, FT-IR, and GC analysis. The average molecular weights of RRPS-1 and RRPS-2 were 8. Read More

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November 2018
1 Read

Metabolomics reveal that octocrylene accumulates in Pocillopora damicornis tissues as fatty acid conjugates and triggers coral cell mitochondrial dysfunction.

Anal Chem 2018 Dec 5. Epub 2018 Dec 5.

Octocrylene (OC) is an ingredient used in many sunscreens and cosmetics worldwide. Our group evaluated the toxicity of OC in corals. Adult Pocillopora damicornis coral was treated with OC at concentrations of 5, 50, 300 and 1000 µg/L. Read More

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December 2018
2 Reads
5.636 Impact Factor

A rapid ultrasonic energy assisted preconcentration method for simultaneous extraction of lead and cadmium in various cosmetic brands using deep eutectic solvent: A multivariate study.

Ultrason Sonochem 2019 Mar 13;51:40-48. Epub 2018 Oct 13.

National Centre of Excellence in Analytical Chemistry, University of Sindh, Jamshoro 76080, Pakistan. Electronic address:

An innovative ultrasonic assisted microextraction method using a deep eutectic solvent for entrapping the organ metallic complexes was developed to pre-concentrate the trace quantities of cadmium (Cd) and lead (Pb) in lipsticks and eye shadows of different brands prior to flame atomic absorption spectrometry analysis. A deep eutectic solvent (DES) was used in this study, prepared by mixing metal salt (ZnCl) and hydrogen bond donors such as (acetamide) in different ratio. The different branded cosmetic items, lipstick and eye shadows, obtained from local market and subjected to acid digestion prior to application of proposed ultrasonic assisted microextraction method based on deep eutectic solvent (UAµE-DES) with the aid of mechanical and ultrasound energies. Read More

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March 2019
1 Read

Evaluation of the Effects of Carbon 60 Nanoparticle Exposure to Adult Zebrafish: A Behavioral and Biochemical Approach to Elucidate the Mechanism of Toxicity.

Int J Mol Sci 2018 Dec 3;19(12). Epub 2018 Dec 3.

Department of Chemistry, Chung Yuan Christian University, Chung-Li 32023, Taiwan.

There is a growing concern for the potential toxicity of engineered nanomaterials that have made their way into virtually all novel applications in the electronics, healthcare, cosmetics, technology, and engineering industries, and in particular, biomedical products. However, the potential toxicity of carbon 60 (C) at the behavioral level has not been properly evaluated. In this study, we used idTracker, a multitracking algorithm to quantitatively assess behavioral toxicity induced by C nanoparticles (C NPs) in adult zebrafish. Read More

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December 2018
3 Reads

Chemical characterization and biological activity of six different extracts of propolis through conventional methods and supercritical extraction.

PLoS One 2018 4;13(12):e0207676. Epub 2018 Dec 4.

Federal University of Bahia, Salvador, Bahia, Brazil.

Propolis is a natural product with many demonstrated biological activities and propolis extract has been used in the food, pharmaceutical and cosmetics industries. Different works have showed the variations in the chemical composition, and consequently, on the biological activity of the propolis that are associated with its type and geographic origin. Due to this study evaluated propolis extracts obtained through supercritical extraction and ethanolic extraction (conventional) in three samples of different types of propolis (red, green and brown), collected from different regions in Brazil (state of Bahia). Read More

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December 2018
6 Reads

Alterations of blood chemistry, hepatic and renal function, and blood cytometry in acrylamide-treated rats.

Toxicol Rep 2018 6;5:1124-1128. Epub 2018 Nov 6.

Facultad de Química Farmacéutica Biológica, Universidad Veracruzana, Xalapa, Veracruz, Mexico.

Acrylamide is a vinyl monomer that is widely used for the synthesis of polyacrylamides, the treatment of drinking water, and as an additive in cosmetics. Acrylamide is also produced during the thermal processing of carbohydrate-rich foods. Although the potential toxic effects of acrylamide have been reported, few studies have evaluated biochemical parameters in blood. Read More

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November 2018
1 Read

Skin anti-inflammatory activity of rose petal extract () through reduction of MAPK signaling pathway.

Food Sci Nutr 2018 Nov 25;6(8):2560-2567. Epub 2018 Oct 25.

Korea Food Research Institute Wanju-gun Korea.

The aim of this study was to investigate the skin anti-inflammatory activity of rose petal extract (RPE) and the mechanisms underlying this phenomenon. Recently, flowers have been considered as dietary resources owing to their biological activities, such as inhibition of nephritis and hemorrhoids. The plant exerts various biological functions, including antioxidant and anti-microbiological activities. Read More

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November 2018
7 Reads

The monoclonal antibody for discrimination of natural honey against artificial honey.

Food Sci Nutr 2018 Nov 25;6(8):2350-2354. Epub 2018 Oct 25.

Department of Biomedical Technology Kangwon National University Chuncheon Korea.

Background: Honey is a natural product used as food, medicine, or cosmetics for very long time and is made by bees. Honey contains various components such as sugar, protein, minerals, and vitamins. Honey is made by or , which commonly has major royal jelly proteins (MRJPs) as a major protein. Read More

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November 2018

Is tartrazine really safe? and toxicological studies in human leukocytes: a question of dose.

Toxicol Res (Camb) 2018 Nov 20;7(6):1128-1134. Epub 2018 Jul 20.

Federal University of Pampa - UNIPAMPA , campus Uruguaiana , RS , Brazil . Email:

The use of food colorings has a long-recorded history. Tartrazine (TRZ) is a dye that confers a lemon-yellow color to food and is widely used in the manufacture of numerous food products, as well as in pharmaceuticals and cosmetics. However, few studies have addressed the toxicology of TRZ in human cells or tissues. Read More

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November 2018
1 Read

Food Yellow4 reprotoxicity in relation to localization of DMC1 and apoptosis in rat testes: Roles of royal jelly and cod liver oil.

Ecotoxicol Environ Saf 2018 Nov 27;169:696-706. Epub 2018 Nov 27.

Laboratory of Anatomy, Department of Biomedical Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Kita-Ku, Sapporo, Japan.

Food Yellow 4 (FY4) is a lemon-yellow-colored synthetic organic azo dye, which is used widely for imparting pleasant and attractive appearance to foods and cosmetics. The present study aimed at evaluating the possible mechanism underlying the FY4-induced reprotoxicity in rats, and the potential supportive role of royal jelly (RJ) or cod liver oil (CLO), which is a natural remedy with several pharmacological benefits, against induced toxicity. Forty-eight male rats were divided into different groups-the control group, the CLO group (0. Read More

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November 2018
3 Reads

Synthetic phenolic antioxidants and their major metabolites in human fingernail.

Environ Res 2018 Nov 16;169:308-314. Epub 2018 Nov 16.

State Key Laboratory of Pollution Control and Resource Reuse, School of the Environment, Nanjing University, Nanjing 210023, China; Soil and Water Science Department, University of Florida, Gainesville, FL 32611, USA.

Synthetic phenolic antioxidants (SPAs) have been widely used in foods, polymers, and cosmetics, but very limited information is available about their occurrence in human tissues. In this study, five SPAs, namely 2,6-di-tert-butyl-4-methylphenol (BHT), 2-tert-butyl-4-hydroxyanisole (BHA), propyl-, octyl-, and dodecyl-gallate (PG, OG, and DG), and four major metabolites of BHT, including 3,5-di-tert-butyl-4 -hydroxybenzaldehyde (BHT-CHO), 2,6-di-tert-butyl-4-(hydroxymethyl) phenol (BHT-OH), 3,5-di-tertbutyl-4-hydroxybenzoic acid (BHT-COOH), and 2,6-di-tert-butyl-1,4-benzoquinone (BHT-Q), were determined in human fingernail samples collected from Nanjing, China. Total concentrations of the nine target analytes (∑SPAs) were 523-14,000 ng/g. Read More

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November 2018
2 Reads

Sex- and age-adjusted prevalence estimates of skin types and unpleasant skin sensations and their consequences on the quality of life: Results from a study of a large representative sample of the French population.

Br J Dermatol 2018 Nov 30. Epub 2018 Nov 30.

Société Française de Dermatologie (SFD), Paris, France.

In France, the consumption of cosmetics was recently evaluated: the mean number of cosmetic products used daily by French consumers is 16 for women (18 if they are pregnant), 8 for men, 7 for girls (4-14 years old), 5 for boys (4-14 years old) and 6 for babies (0-3 years old, both sexes) , especially facial moisturizers, with a higher product exposure amounts than expected. Nonetheless, little is known about the prevalence of cosmetic disorders in the general population. This article is protected by copyright. Read More

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November 2018

Potential of two delivery systems for nisin topical application to dental plaque biofilms in dogs.

BMC Vet Res 2018 Nov 29;14(1):375. Epub 2018 Nov 29.

CIISA - Centro de Investigação Interdisciplinar em Sanidade Animal, Faculdade de Medicina Veterinária, Universidade de Lisboa, Avenida da Universidade Técnica, 1300-477, Lisboa, Portugal.

Background: Periodontal disease (PD) is caused by the development of a microbial biofilm (dental plaque) in the periodontium, affecting approximately 80% of dogs. Several bacterial species present in the canine oral cavity can be implicated in the development of this disease, including Enterococcus spp. To decrease antibiotic administration, a possible control strategy for dog's enterococcal PD may involve the use of the antimicrobial peptide (AMP) nisin. Read More

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November 2018
1 Read

Genome and Transcriptome Sequencing of the Astaxanthin-Producing Green Microalga, Haematococcus pluvialis.

Genome Biol Evol 2018 Nov 29. Epub 2018 Nov 29.

Guangdong Technology Research Center for Marine Algal Bioengineering, Guangdong Key Laboratory of Plant Epigenetic, Shenzhen Key Laboratory of Marine Bioresource & Eco-environmental Sciences, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, Guangdong, China.

Haematococcus pluvialis is a freshwater species of Chlorophyta, family Haematococcaceae. It is well known for its capacity to synthesize high amounts of astaxanthin, which is a strong antioxidant that has been utilized in aquaculture and cosmetics. To improve astaxanthin yield and to establish genetic resources for H. Read More

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November 2018

Computational approaches for skin sensitization prediction.

Crit Rev Toxicol 2018 Nov 29:1-23. Epub 2018 Nov 29.

a Center for Bioinformatics, Universität Hamburg , Hamburg , Germany.

Drugs, cosmetics, preservatives, fragrances, pesticides, metals, and other chemicals can cause skin sensitization. The ability to predict the skin sensitization potential and potency of substances is therefore of enormous importance to a host of different industries, to customers' and workers' safety. Animal experiments have been the preferred testing method for most risk assessment and regulatory purposes but considerable efforts to replace them with non-animal models and in silico models are ongoing. Read More

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November 2018
1 Read

The bra strap incision in the open Latarjet procedure.

J Orthop Surg Res 2018 Nov 29;13(1):304. Epub 2018 Nov 29.

Department of Orthopaedics, University of Zurich, Balgrist University Hospital, Forchstrasse 340, CH-8008, Zürich, Switzerland.

Background: The anterior deltopectoral approach is the standard approach for performing the open Latarjet procedure. Through the use of a more medial and vertical skin incision, the scar can be cosmetically covered by the bra strap in women. We call this incision the bra strap incision. Read More

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November 2018
1 Read

Nanofibers for Biomedical and Healthcare Applications.

Macromol Biosci 2018 Nov 28:e1800256. Epub 2018 Nov 28.

LGP2, Grenoble INP, CNRS, Université Grenoble Alpes, F-38000, Grenoble, France.

Unique features of nanofibers provide enormous potential in the field of biomedical and healthcare applications. Many studies have proven the extreme potential of nanofibers in front of current challenges in the medical and healthcare field. This review highlights the nanofiber technologies, unique properties, fabrication techniques (i. Read More

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November 2018

A preliminary review of studies on adaptogens: comparison of their bioactivity in TCM with that of ginseng-like herbs used worldwide.

Chin Med 2018 16;13:57. Epub 2018 Nov 16.

3Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, 151 Malianwa North Road, Haidian District, Beijing, 100193 People's Republic of China.

Modern studies have shown that adaptogens can non-specifically enhance the resistance of human body under a wide range of external stress conditions with a multi-targeted and multi-channel network-like manner, especially by affect the immune-neuro-endocrine system and the hypothalamic-pituitary-adrenal axis. This review article draws the attention to the relationships of adaptogens, tonics from traditional Chinese medicine (TCM) and ginseng-like herbs worldwide, which all have similar plant sources and clinical applications. To clarify the sources and pharmacological mechanisms of these plant-originated adaptogens, which will provide useful information for the utilization of adaptogens to improve the human health. Read More

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November 2018
2.343 Impact Factor

Recent Patents, Formulation Techniques, Classification and Characterization of Liposomes.

Recent Pat Nanotechnol 2018 Nov 26. Epub 2018 Nov 26.

Department of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak 124001. India.

Background: During past decades' liposomes have emerged as efficient carriers for drugs, diagnostics, vaccines, nutrients and other bioactive agents. Liposomes, the spherical vesicles consisting of phospholipids bilayer have the ability to encapsulate both lipophilic and hydrophilic drugs. Extensive studies have been done in the past for investigating a number of drugs and genes for controlled release with liposomal formulation. Read More

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November 2018
6 Reads

Separation of nine novel triterpene saponins from Camellia japonica seeds using high-performance countercurrent chromatography and reversed-phase high-performance liquid chromatography.

Phytochem Anal 2018 Nov 26. Epub 2018 Nov 26.

College of Pharmacy and Integrated Research Institute of Pharmaceutical Science, The Catholic University of Korea, Bucheon, Gyeonggi Province, Republic of Korea.

Introduction: Camellia japonica L. (Theaceae) is an evergreen shrub, which is cultivated as a popular ornamental tree in Korea, China, and Japan and its seeds have been used as a source of cooking oil, in cosmetics and as a traditional medicine. Intensive phytochemical works have revealed that oleanane-type saponins are the characteristic compounds of the seeds of C. Read More

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November 2018

Elicited ROS Scavenging Activity, Photoprotective, and Wound-Healing Properties of Collagen-Derived Peptides from the Marine Sponge .

Mar Drugs 2018 Nov 23;16(12). Epub 2018 Nov 23.

Department of Earth, Environment and Life Sciences (DISTAV), University of Genova, Via Pastore 3, 16132 Genova, Italy.

Recently, the bioactive properties of marine collagen and marine collagen hydrolysates have been demonstrated. Although there is some literature assessing the general chemical features and biocompatibility of collagen extracts from marine sponges, no data are available on the biological effects of sponge collagen hydrolysates for biomedical and/or cosmetic purposes. Here, we studied the in vitro toxicity, antioxidant, wound-healing, and photoprotective properties of four HPLC-purified fractions of trypsin-digested collagen extracts-marine collagen hydrolysates (MCHs)-from the marine sponge . Read More

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November 2018

In-depth synthetic, physicochemical and in vitro biological investigation of a new ternary V(IV) antioxidant material based on curcumin.

J Inorg Biochem 2018 Nov 6;191:94-111. Epub 2018 Nov 6.

Laboratory of Inorganic Chemistry and Advanced Materials, Department of Chemical Engineering, Aristotle University of Thessaloniki, Thessaloniki 54124, Greece. Electronic address:

Curcumin is a natural product with a broad spectrum of beneficial properties relating to pharmaceutical applications, extending from traditional remedies to modern cosmetics. The biological activity of such pigments, however, is limited by their solubility and bioavailability, thereby necessitating new ways of achieving optimal tissue cellular response and efficacy as drugs. Metal ion complexation provides a significant route toward improvement of curcumin stability and biological activity, with vanadium being a representative such metal ion, amply encountered in biological systems and exhibiting exogenous bioactivity through potential pharmaceuticals. Read More

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November 2018
2 Reads

Evaluation of parabens and their metabolites in fish and fish products: a comprehensive analytical approach using LC-HRMS.

Food Addit Contam Part A Chem Anal Control Expo Risk Assess 2018 Nov 26:1-14. Epub 2018 Nov 26.

a Department of Health, Animal Science and Food Safety , University of Milan , Milan , Italy.

Parabens (PBs) are preservatives frequently used in cosmetics and personal care products as well as in the pharmaceutical and food industries due to their extensive defence mechanisms against multiple categories of microorganisms. Although they are considered safe when used within defined concentration limits, concern about their potential toxicity is still particularly active. Revealed as emerging pollutants, their incidence and behaviour in the aquatic environment have been studied, but there is only sporadic information when it comes to their extent and distribution in seafood. Read More

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November 2018

Toxicity and mechanisms of action of titanium dioxide nanoparticles in living organisms.

J Environ Sci (China) 2019 Jan 27;75:40-53. Epub 2018 Jun 27.

College of Environmental Science and Engineering, North China Electric Power University, Beijing 102206, China. Electronic address:

Titanium dioxide nanoparticles (TiO NPs) are one of the most widely used nanomaterials in the consumer products, agriculture, and energy sectors. Their large demand and widespread applications will inevitably cause damage to organisms and ecosystems. A better understanding of TiO NP toxicity in living organisms may promote risk assessment and safe use practices of these nanomaterials. Read More

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January 2019
5 Reads

Sorption of uranyl ions on TiO: Effects of pH, contact time, ionic strength, temperature and HA.

J Environ Sci (China) 2019 Jan 17;75:115-123. Epub 2018 Mar 17.

Radiochemistry Laboratory, School of Nuclear Science and Technology, Lanzhou University, Lanzhou 730000, China. Electronic address:

Sorption of U(VI) onto TiO as functions of pH, ionic strength, contact time, soil humic acid (SHA), solid-to-liquid ratio and temperature was studied under ambient conditions using batch and spectroscopic approaches. The sorption of U(VI) on TiO was significantly dependent on pH and ionic strength. The presence of SHA slightly enhanced the sorption of U(VI) on TiO below pH4. Read More

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January 2019
1 Read

Recent advances in body-on-a-chip systems.

Anal Chem 2018 Nov 26. Epub 2018 Nov 26.

Microphysiological systems (MPS, also known as 'organ-on-a-chip', 'body-on-a-chip', or 'human-on-a-chip') have emerged over the last fifteen years as attractive systems to probe response to pharmaceutical or chemicals. While applicable to animals, such systems are particularly powerful in predicting human response prior to clinical testing of a drug or as augmentation of clinical studies to test underlying mechanisms. The rate of development of such systems has increased exponentially, particularly over the last three years. Read More

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November 2018
1 Read

Definition of a measurement scale of graininess from reflectance and visual measurements.

Opt Express 2018 Nov;26(23):30116-30127

Effect pigments in coatings produce eye-catching colour and texture effects and are widely used in automotive, cosmetics, coatings, inks, flooring, textile or decoration. One of these texture effects is graininess, which is the perceived texture exhibited when the effect coating is observed under diffuse illumination. To date there is not a standard procedure to measure graininess from reflectance measurements. Read More

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November 2018
2 Reads

Determining the surface dilational rheology of surfactant and protein films with a droplet waveform generator.

J Colloid Interface Sci 2018 Nov 14;537:547-553. Epub 2018 Nov 14.

Department of Mechanical Engineering, University of Hawaii at Manoa, Honolulu, HI 96822, United States; Department of Pediatrics, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI 96826, United States. Electronic address:

Understanding rheological properties of surfactant and protein films plays a crucial role in a variety of industrial and research areas, such as food processing, cosmetics, and pharmacology. To determine the surface dilational modulus using drop shape analysis, one needs to measure the dynamic surface tension in response to a sinusoidal oscillation of the surface area of the droplet. Despite many applications of drop shape analysis in studying interfacial rheology, oscillation of the droplet surface area is usually controlled in an indirect manner. Read More

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November 2018

Cosmeceuticals: What's Real, What's Not.

Dermatol Clin 2019 Jan 1;37(1):107-115. Epub 2018 Nov 1.

Dermatology Consulting Services, PLLC, 2444 North Main Street, High Point, NC 27262, USA. Electronic address:

Cosmeceuticals are cosmetics that promise to deliver physiologically relevant benefits without the incorporation of prescription drugs. To entice consumers to purchase these premium priced products, a story must be told of how the cosmeceutical delivers on these appearance improvement promises. The backbone of any cosmeceutical skin care regimen is facial cleansing and moisturizing. Read More

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January 2019

Preparation of Sliver and Selenium Nanoparticles and Its Characterization by Dynamic Light Scattering and Scanning Electron Microscopy.

J Microsc Ultrastruct 2018 Oct-Dec;6(4):182-187

Department of Bio Science and Technology, Shri Ramswaroop Memorial University, Lucknow-Deva Road, Lucknow, Uttar Pradesh, India.

Aim: In our study, two different methods were used to determine the size and size distribution of the sliver and selenium nanoparticles via dynamic light scattering (DLS) and scanning electron microscopy (SEM).

Background: Nanotechnology dealing with metal and metalloid nanoparticles has been usually applied in nearly each field of science, engineering, and technology including biology and medicine etc due to presence of size and shape dependent unusual physical and chemical properties. In the most recent decade, numerous groups including appreciably developed metal and metalloid nanoparticles based theranostic approaches for the treatment of almost human diseases. Read More

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November 2018
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Allergic reactions to hydrolysed wheat proteins: clinical aspects and molecular structures of the allergens involved.

Crit Rev Food Sci Nutr 2018 Nov 21:1-10. Epub 2018 Nov 21.

a UR1268 BIA - INRA (Institut National De La Recherche Agronomique) , Nantes , France.

Wheat gluten can be chemically or enzymatically hydrolysed to produce functional ingredients useful in food and cosmetics. However severe allergies to hydrolysed wheat proteins (HWP) have been described in Europe and Japan since the early 2000's. Triggering proteins and IgE epitopes were described both for French and Japanese cohorts and appeared remarkably similar leading to define a new wheat allergic entity. Read More

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November 2018
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Squalene Found in Alpine Grassland Soils under a Harsh Environment in the Tibetan Plateau, China.

Biomolecules 2018 Nov 20;8(4). Epub 2018 Nov 20.

Institute of Mountain Hazards and Environment, Chinese Academy of Sciences, Chengdu 610041, China.

Squalene is found in a large number of plants, animals, and microorganisms, as well as other sources, playing an important role as an intermediate in sterol biosynthesis. It is used widely in the food, cosmetics, and medicine industries because of its antioxidant, antistatic, and anti-carcinogenic properties. A higher natural squalene component of lipids is usually reported as being isolated to organisms living in harsh environments. Read More

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November 2018
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The electronic transitions of analogs of red wine pyranoanthocyanin pigments.

Photochem Photobiol Sci 2018 Nov 21. Epub 2018 Nov 21.

School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, People's Republic of China. and Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, Texas 79409-1061, USA and Institute for Soil Research, University of Natural Resources and Life Sciences Vienna, Peter-Jordan-Strasse 82, A-1190 Vienna, Austria.

There is increasing interest in using natural colorants like anthocyanins in cosmetics, food and pharmaceuticals as replacements for synthetic colorants. During the maturation of red wines, the anthocyanin pigments contained in grapes are transformed via reaction with copigments and metabolic products into pyranoanthocyanins, responsible in part for the final color of the wine. In order to understand structural effects on the absorption spectra of pyranoanthocyanins, the calculated excited state energies and spectroscopic states of a series of substitued pyranoflavylium cation analogs of pyranoanthocyanins have been compared to experimental spectroscopic data for these compounds. Read More

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November 2018
3 Reads