Search our Database of Scientific Publications and Authors

I’m looking for a

    52988 results match your criteria Cosmetics

    1 OF 1060

    Modified Lateral Surgical Approach to the Pterygopalatine Fossa.
    J Craniofac Surg 2017 Feb 22. Epub 2017 Feb 22.
    *Department of Science of Physical Functions, Division of Maxillofacial Surgery, Kyushu Dental University †Department of Dental Anesthesiology, Kyushu Dental University, Kitakyushu, Japan.
    Oral cancer, especially that originates in the maxillary tuberosity, buccal mucosa, and maxillary alveolus, is apt to invade the pterygopalatine fossa, where an intraoral approach is nearly impossible. There are 2 main types of extraoral approach to the pterygopalatine fossa; the anterior approach and the lateral approach. Although the lateral approach has an advantage compared with the anterior approach in terms of cosmetics, after the operation numbness of the lower lip occurs due to the sacrifice of the mental nerve. Read More

    Simultaneous determination of seven nitrogen-containing phenyl ethers in cosmetics by gas chromatography with mass spectrometry and dispersive solid-phase extraction.
    J Sep Sci 2017 Feb 23. Epub 2017 Feb 23.
    National Centre for Quality Supervision and Testing of Processed Food (Guangzhou), Guangzhou Quality Supervision and Testing Institute, Guangzhou, China.
    An analytical method was established for the simultaneous determination of seven nitrogen-containing phenyl ethers (2-anisidine, 3-anisidine, 4-anisidine, 2-nitroanisole, 3-nitroanisole, 4-nitroanisole and 3,3'-dimethoxybenzidine) in cosmetics by gas chromatography with mass spectrometry in this work. The samples were extracted with ethyl acetate and purified with primary secondary amine during the dispersed solid phase extraction. The analytes were separated by a DB-17MS column and detected in the electron ionization mode of mass spectrometry in the selected ions monitoring mode. Read More

    Engineering rTCA pathway and C4-dicarboxylate transporter for L-malic acid production.
    Appl Microbiol Biotechnol 2017 Feb 22. Epub 2017 Feb 22.
    State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, 214122, China.
    L-Malic acid is an important component of a vast array of food additives, antioxidants, disincrustants, pharmaceuticals, and cosmetics. Here, we presented a pathway optimization strategy and a transporter modification approach to reconstruct the L-malic acid biosynthesis pathway and transport system, respectively. First, pyruvate carboxylase (pyc) and malate dehydrogenase (mdh) from Aspergillus flavus and Rhizopus oryzae were combinatorially overexpressed to construct the reductive tricarboxylic acid (rTCA) pathway for L-malic acid biosynthesis. Read More

    FEA modeling and fluid flow simulation of human rectum with inserted bowel catheters.
    Conf Proc IEEE Eng Med Biol Soc 2016 Aug;2016:2652-2655
    In this project, fluid flow and fluid-structure interaction are studied for the human lower gastrointestinal (GI) region. The study consists of two steps. First, we apply meshing methods to discretize both the human lower GI model and the catheter model at sufficient resolution suitable for importing into a Finite Element Analysis (FEA) tool. Read More

    Structural changes in cartilage and collagen studied by high temperature Raman spectroscopy.
    Biopolymers 2017 Feb 22. Epub 2017 Feb 22.
    Department of Chemistry, University College London, 20 Gordon Street, London, WC1H 0AJ, UK.
    Understanding the high temperature behavior of collagen and collagenous tissue is important for surgical procedures and biomaterials processing for the food, pharmaceutical and cosmetics industries. One primary event for proteins is thermal denaturation that involves unfolding the polypeptide chains while maintaining the primary structure intact. Collagen in the extracellular matrix of cartilage and other connective tissue is a hierarchical material containing bundles of triple-helical fibers associated with water and proteoglycan components. Read More

    Kinetin Improves Barrier Function of the Skin by Modulating Keratinocyte Differentiation Markers.
    Ann Dermatol 2017 Feb 2;29(1):6-12. Epub 2017 Feb 2.
    Korea Institute for Skin and Clinical Sciences, Konkuk University, Seoul, Korea.
    Background: Kinetin is a plant hormone that regulates growth and differentiation. Keratinocytes, the basic building blocks of the epidermis, function in maintaining the skin barrier.

    Objective: We examined whether kinetin induces skin barrier functions in vitro and in vivo. Read More

    Bio-based materials with novel characteristics for tissue engineering applications - A review.
    Int J Biol Macromol 2017 Feb 14;98:837-846. Epub 2017 Feb 14.
    School of Engineering and Science, Tecnologico de Monterrey, Campus Monterrey, Ave. Eugenio Garza Sada 2501, Monterrey, N.L. CP 64849, Mexico. Electronic address:
    Recently, a wider spectrum of bio-based materials and materials-based novel constructs and systems has been engineered with high interests. The key objective is to help for an enhanced/better quality of life in a secure way by avoiding/limiting various adverse effects of some in practice traditional therapies. In this context, different methodological approaches including in vitro, in vivo, and ex vivo techniques have been exploited, so far. Read More

    Position 228 in Paenibacillus macerans cyclodextrin glycosyltransferase is critical for 2-O-d-glucopyranosyl-l-ascorbic acid synthesis.
    J Biotechnol 2017 Feb 17. Epub 2017 Feb 17.
    State Key Laboratory of Food Science and Technology, Jiangnan University, 1800 Lihu Avenue, Wuxi, 214122, China; School of Biotechnology and Key Laboratory of Industrial Biotechnology, Ministry of Education, Jiangnan University, 1800 Lihu Avenue, Wuxi, 214122, China. Electronic address:
    The markedly stable l-ascorbic acid (L-AA) derivative 2-O-d-glucopyranosyl-l-ascorbic acid (AA-2G) has been widely used in the fields of food, medicine, cosmetics, and husbandry. Cyclodextrin glycosyltransferase (CGTase) is considered suitable for the large-scale production of AA-2G. In this work, Paenibacillus macerans CGTase was used to produce AA-2G and the production was 13. Read More

    Hydrophilic Dogwood Extracts as Materials for Reducing the Skin Irritation Potential of Body Wash Cosmetics.
    Molecules 2017 Feb 19;22(2). Epub 2017 Feb 19.
    Department of Cosmetology, The University of Information Technology and Management in Rzeszow, Kielnarowa 386a, Tyczyn 36-020, Poland.
    A significant problem related to the use of surfactants in body wash cosmetics is their propensity to trigger skin irritations. Only scarce literature exists on the effect of plant extracts on the skin irritation potential. The present study is an attempt to determine the effect of hydrophilic dogwood extracts on the irritant potential of body wash gels. Read More

    Effect of Absolute From Hibiscus syriacus L. Flower on Wound Healing in Keratinocytes.
    Pharmacogn Mag 2017 Jan-Mar;13(49):85-89
    Department of Cosmetic Science, College of Life and Health Sciences, Hoseo University, Asan, Chungnam Prefecture, Republic of Korea.
    Background: Proliferation and migration of keratinocytes are essential for the repair of cutaneous wounds. Hibiscus syriacus L. has been used in Asian medicine; however, research on keratinocytes is inadequate. Read More

    Color matching in facial prosthetics: A systematic review.
    J Indian Prosthodont Soc 2017 Jan-Mar;17(1):3-7
    Department of Prosthodontics, Faculty of Dental Sciences, King George's Medical University, Lucknow, Uttar Pradesh, India.
    Color matching to the surrounding skin is extremely important in patients wearing maxillofacial prostheses. It is of utmost importance to know the different techniques of color matching and coloring in maxillofacial prostheses. The purpose of this study is to review the literature data with regard to color matching in maxillofacial prosthetics. Read More

    Harnessing Nanoparticles for Immunomodulation and Vaccines.
    Vaccines (Basel) 2017 Feb 14;5(1). Epub 2017 Feb 14.
    The Jenner Institute, Oxford University, Old Road Campus Research Building, Roosevelt Drive, Oxford OX3 7DQ, UK.
    The first successful use of nanoparticles (NPs) for vaccination was reported almost 40 years ago with a virus-like particle-based vaccine against Hepatitis B. Since then, the term NP has been expanded to accommodate a large number of novel nano-sized particles engineered from a range of materials. The great interest in NPs is likely not only a result of the two successful vaccines against hepatitis B and Human Papilloma Virus (HPV) that use this technology, but also due to the versatility of those small-sized particles, as indicated by the wide range of applications reported so far, ranging from medicinal and cosmetics to purely technical applications. Read More

    Margin of safety for two UV filters estimated by in vitro permeation studies mimicking consumer habits: Effects of skin shaving and sunscreen reapplication.
    Food Chem Toxicol 2017 Feb 16. Epub 2017 Feb 16.
    Laboratories of Cosmetology, Faculty of Chemical and Food Technology, Slovak University of Technology, Radlinského 9, 812 37 Bratislava, Slovak Republic. Electronic address:
    Sunscreens are intended to work on the skin. To be both efficient and safe, the lowest possible percutaneous permeation of UV filters should occur. The potential for systemic absorption of Benzophenone-3 (BP3, 10%) and Ethylhexyl Triazone (EHT, 5%) in a silicone-based water-in-oil emulsion was assessed in vitro using a fullthickness porcine-ear skin mimicking in-use conditions. Read More

    Evaluation of the GARD assay in a blind Cosmetics Europe study.
    ALTEX 2017 Feb 17. Epub 2017 Feb 17.
    Dept. of Immunotechnology, Lund University, Lund, Sweden.
    Chemical hypersensitivity is an immunological response towards foreign substances, commonly referred to as sensitizers, which gives rise primarily to the clinical symptoms known as allergic contact dermatitis. For the purpose of mitigating risks associated with consumer products, chemicals are screened for sensitizing effects. Historically, such predictive screenings have been performed using animal models. Read More

    Preparation and biocompatibility of a chitin nanofiber/gelatin composite film.
    Int J Biol Macromol 2017 Feb 16. Epub 2017 Feb 16.
    Graduate School of Engineering, Tottori University, Tottori 680-8552, Japan. Electronic address:
    The development of chitin-based materials with favorable mechanical properties and biocompatibility is an important research goal owing to the wide-ranging practical applications. In this study, a composite film was prepared using chitin nanofibers and gelatin. The CNF/gelatin composite film was highly viscous and had a fine nanofiber structure. Read More

    Topical Formulation Containing Beeswax-Based Nanoparticles Improved In Vivo Skin Barrier Function.
    AAPS PharmSciTech 2017 Feb 17. Epub 2017 Feb 17.
    School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Av. do Café s/n, Campus USP, 14040-903, Ribeirão Preto, São Paulo, Brazil.
    Lipid nanoparticles have shown many advantages for treatment/prevention of skin disorders with damaged skin barrier function. Beeswax is a favorable candidate for the development of nanosystems in the cosmetic and dermatological fields because of its advantages for the development of products for topical application. In the present study, beeswax-based nanoparticles (BNs) were prepared using the hot melt microemulsion technique and incorporated to a gel-cream formulation. Read More

    A novel and sensitive fluorescence sensor for glutathione detection by controlling the surface passivation degree of carbon quantum dots.
    Talanta 2017 May 11;166:1-7. Epub 2017 Jan 11.
    Department of Chemistry and Laboratory for Preparation and Application of Ordered Structural Materials of Guangdong Province, Shantou University, Shantou, Guangdong 515063, PR China. Electronic address:
    A novel fluorescence sensor based on controlling the surface passivation degree of carbon quantum dots (CQDs) was developed for glutathione (GSH) detection. First, we found that the fluorescence intensity of the CQDs which was obtained by directly pyrolyzing citric acid would increased largely after the surface passivation treatment by 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide (EDC). In the light of this phenomenon, we designed a simple, rapid and selective fluorescence sensor based on the surface passivated CQDs. Read More

    Enzyme-Assisted Discovery of Antioxidant Peptides from Edible Marine Invertebrates: A Review.
    Mar Drugs 2017 Feb 16;15(2). Epub 2017 Feb 16.
    Department of Marine Bio-Convergence Science, Pukyong National University, 48513 Busan, Korea.
    Marine invertebrates, such as oysters, mussels, clams, scallop, jellyfishes, squids, prawns, sea cucumbers and sea squirts, are consumed as foods. These edible marine invertebrates are sources of potent bioactive peptides. The last two decades have seen a surge of interest in the discovery of antioxidant peptides from edible marine invertebrates. Read More

    Evaluation of in vivo and in vitro toxicological and genotoxic potential of aluminum chloride.
    Chemosphere 2017 Feb 3;175:130-137. Epub 2017 Feb 3.
    Molecular Biology Laboratory - Post Graduate Program of Amazon Parasitic Biology, Biological and Health Sciences Center, State University of Pará, Belém, Pará, Brazil.
    Aluminum and its compounds are common contaminants of water and food, as well as medications and cosmetics. The wide distribution of the element facilitates the demand for detailed studies of its biological and toxicological effects. This work aimed to evaluate the possible genotoxic and toxic activity resulting from in vivo and in vitro exposure to Al. Read More

    Hydroxycinnamic Acids and Their Derivatives: Cosmeceutical Significance, Challenges and Future Perspectives, a Review.
    Molecules 2017 Feb 13;22(2). Epub 2017 Feb 13.
    Mountain Research Centre (CIMO), ESA, Polytechnic Institute of Bragança, Campus de Santa Apolónia, 1172, 5300-253 Bragança, Portugal.
    Bioactive compounds from natural sources, due to their widely-recognized benefits, have been exploited as cosmeceutical ingredients. Among them, phenolic acids emerge with a very interesting potential. In this context, this review analyzes hydroxycinnamic acids and their derivatives as multifunctional ingredients for topical application, as well as the limitations associated with their use in cosmetic formulations. Read More

    Chemiluminescence of Lucigenin-Allantoin and Its Application for the Detection of Allantoin.
    Anal Chem 2017 Feb 11;89(3):1863-1869. Epub 2017 Jan 11.
    State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences , 5625 Renmin Street, Changchun, Jilin 130022, PR China.
    Allantoin has been reported as a promising biomarker for monitoring of oxidative stress in humans and widely utilized in a variety of topical pharmaceuticals and cosmetics. Currently, the detection of allantoin is achieved by using chromatographic coupled techniques, which needs sample pre-extraction, derivatization, complex matrixes, and expensive instrumentation. Herein we report both the intense chemiluminescence of allantoin with lucigenin and the chemiluminescent detection of allantoin for the first time. Read More

    Toxicity of internalized laser generated pure silver nanoparticles to the isolated rat hippocampus cells.
    Toxicol Ind Health 2017 Jan 1:748233717690992. Epub 2017 Jan 1.
    1 UNAM - National Nanotechnology Research Center, Bilkent University, Ankara, Turkey.
    Silver nanoparticles (AgNPs) are the most commonly used nanoparticles (NPs) in medicine, industry and cosmetics. They are generally considered as biocompatible. However, contradictory reports on their biosafety render them difficult to accept as 'safe'. Read More

    Physicochemical characteristics of the cold-pressed oil obtained from seeds of Fagus sylvatica L.
    Food Chem 2017 Jun 6;225:239-245. Epub 2017 Jan 6.
    Department of Biochemistry and Food Analysis, Poznań University of Life Sciences, Wojska Polskiego 28, 60-637 Poznan, Poland.
    A physicochemical characteristic of the cold-pressed oil obtained from seeds of common beech (Fagus sylvatica L.) has been presented. This plant may be considered as unconventional oilseeds crops because of relatively high content of fat (27. Read More

    Glutamate dehydrogenase (RocG) in Bacillus licheniformis WX-02: Enzymatic properties and specific functions in glutamic acid synthesis for poly-γ-glutamic acid production.
    Enzyme Microb Technol 2017 Apr 6;99:9-15. Epub 2017 Jan 6.
    Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, College of Life Sciences, Hubei University, Wuhan 430062, People's Republic of China. Electronic address:
    Poly-γ-glutamic acid (γ-PGA), a natural biopolymer, is widely used in cosmetics, medicine, food, water treatment, and agriculture owing to its features of moisture sequestration, cation chelation, non-toxicity and biodegradability. Intracellular glutamic acid, the substrate of γ-PGA, is a limiting factor for high yield in γ-PGA production. Bacillus subtilis and Bacillus licheniformis are both important γ-PGA producing strains, and B. Read More

    Relating emulsion stability to interfacial properties for pharmaceutical emulsions stabilized by Pluronic F68 surfactant.
    Int J Pharm 2017 Feb 10;521(1-2):8-18. Epub 2017 Feb 10.
    Department of Chemical Engineering, University of Florida, 1030 Center Drive, Gainesville, FL, 32611, United States. Electronic address:
    We explore mechanisms of emulsion stability for several systems using Pluronic F68 and a range of oils commonly used in pharmaceutics and cosmetics. We report measurements of dynamic emulsion drop size, zeta potential, and creaming time, as well as dynamic interfacial tension and interfacial viscoelasticity. Experiments show that with 1wt% Pluronic F68, soybean oil emulsions were the most stable with no creaming over six months, followed by isopropyl myristate, octanoic acid, and then ethyl butyrate. Read More

    Action of 2,2',4,4'-tetrahydroxybenzophenone in the biosynthesis pathway of melanin.
    Int J Biol Macromol 2017 Feb 10;98:622-629. Epub 2017 Feb 10.
    GENZ-Group of Research on Enzymology(1), Department of Biochemistry and Molecular Biology-A, Regional Campus of International Excellence "Campus Mare Nostrum", University of Murcia, E-30100, Espinardo, Murcia, Spain. Electronic address:
    2,2',4,4'-tetrahydroxybenzophenone (Uvinul D50), a sunscreen used in cosmetics, has two effects in the melanin biosynthesis pathway. On the one hand, it acts a weak inhibitor of tyrosinase and on the other, it accelerates the conversion of dopachrome to melanin. Uvinul D50 was seen to behave as a weak competitive inhibitor: apparent constant inhibition=2. Read More

    Is the European regulatory framework sufficient to assure the safety of citizens using health products containing nanomaterials?
    Drug Discov Today 2017 Feb 9. Epub 2017 Feb 9.
    Department of Pharmaceutical Sciences, Università degli Studi di Milano, Via G. Colombo, 71, 20133 Milan, Italy. Electronic address:
    The growing application of nanomaterials in healthcare products (i.e., cosmetics, medical devices, and medicinal products) has encouraged the upgrade of the regulatory framework within the European Community to better control their use and manage the risk of negative effects on human health and environment. Read More

    New insights into highly potent tyrosinase inhibitors based on 3-heteroarylcoumarins: Anti-melanogenesis and antioxidant activities, and computational molecular modeling studies.
    Bioorg Med Chem 2017 Mar 31;25(5):1687-1695. Epub 2017 Jan 31.
    Department of Life Science and Environment, University of Cagliari, 09042 Monserrato, Cagliari, Italy.
    Melanogenesis is a physiological pathway for the formation of melanin. Tyrosinase catalyzes the first step of this process and down-regulation of its activity is responsible for the inhibition of melanogenesis. The search for molecules capable of controlling hyperpigmentation is a trend topic in health and cosmetics. Read More

    Current lipid extraction methods are significantly enhanced adding a water treatment step in Chlorella protothecoides.
    Microb Cell Fact 2017 Feb 11;16(1):26. Epub 2017 Feb 11.
    Research Laboratory in Applied Metabolic Engineering, Department of Chemical Engineering, École Polytechnique de Montreal, P.O. Box 6079, Centre-ville Station, Montreal, QC, H3C 3A7, Canada.
    Background: Microalgae have the potential to rapidly accumulate lipids of high interest for the food, cosmetics, pharmaceutical and energy (e.g. biodiesel) industries. Read More

    Heteroagglomeration of zinc oxide nanoparticles with clay mineral modulates the bioavailability and toxicity of nanoparticle in Tetrahymena pyriformis.
    J Colloid Interface Sci 2017 Jan 27;495:9-18. Epub 2017 Jan 27.
    Division of Biological & Life Sciences, School of Arts & Sciences, Ahmedabad University, University Road, Navrangpura, Ahmedabad, 380009 Gujarat, India. Electronic address:
    The extensive use of zinc oxide nanoparticles (ZnO NPs) in cosmetics, sunscreens and healthcare products increases their release in the aquatic environment. The present study explored the possible interaction of ZnO NPs with montmorillonite clay minerals in aqueous conditions. An addition of ZnO NPs on clay suspension significantly (p<0. Read More

    Endocrine-disrupting effects of methylparaben on the adult gerbil prostate.
    Environ Toxicol 2017 Feb 9. Epub 2017 Feb 9.
    Department of Histology, Embryology and Cell Biology, Laboratory of Histophysiology, Institute of Biological Sciences, Federal University of Goiás, Goiânia, Goiás, 74001970, Brazil.
    Parabens are xenoestrogens widely employed in cosmetics, foodstuffs, and pharmaceutical products. These chemicals are known to disrupt hormone-dependent organs, due to their binding affinity for hormonal receptors. Although recent studies have evaluated the endocrine-disrupting potential of parabens in several reproductive organs, few have investigated the effects of these chemicals in the prostate. Read More

    Malvidin 3-Glucoside-Fatty Acid Conjugates: From Hydrophilic toward Novel Lipophilic Derivatives.
    J Agric Food Chem 2017 Feb 16. Epub 2017 Feb 16.
    REQUIMTE/LAQV, Departamento de Quı́mica e Bioquı́mica, Faculdade de Ciências, Universidade do Porto , Rua do Campo Alegre 687, 4169-007 Porto, Portugal.
    This work describes the lipophilization reactions of malvidin 3-glucoside with different saturated fatty acid chain lengths using an enzymatic synthesis and the study of their physical-chemical and antioxidant properties. The lipophilic anthocyanins were obtained with satisfactory yields (22-40%) after column chromatography purifications, and they revealed the same appealing chromatic features of the parent anthocyanin. All of the compounds were characterized by mass spectrometry, confirming the regioselective acylation on the glucose moiety. Read More

    Development and Clinical Validation of a Novel Photography-based Skin Erythema Evaluation System: A Comparison with the Calculated Consensus of Dermatologists.
    Int J Cosmet Sci 2017 Feb 8. Epub 2017 Feb 8.
    Department of Biomedical Engineering, Seoul National University College of Medicine, Seoul, 110-799, Korea.
    Erythema is the most common presenting sign of skin conditions [1,2]. Erythema reflects the degree of inflammation associated with various diseases, such as atopic dermatitis, psoriasis, and lupus erythematosus; it is also cosmetically troublesome in subjects with flushing, rosacea, and photoaging [3,4]. In addition, there are vascular disorders that present with erythema, such as nevus flammeus, telangiectasia, and post-acne erythema [5]. Read More

    Contact allergy caused by isothiazolinone derivatives: an overview of non-cosmetic and unusual cosmetic sources.
    Eur J Dermatol 2017 Feb 3. Epub 2017 Feb 3.
    Dermatochemistry laboratory, Institute of Chemistry, University of Strasbourg, Strasbourg, France.
    The isothiazolinone derivatives, methylchloroisothiazolinone (MCI), methylisothiazolinone (MI), benzisothiazolinone (BIT), and octylisothiazolinone (OIT), owing to their strong bactericide, fungicide and algicide properties, are widely used in non-cosmetic products, such as chemical (industrial) products, household detergents, and water-based paints, and the former two derivatives are also used in cosmetic products. However, given their inherent sensitization potential (with MCI > MI > BIT > OIT), allergic contact dermatitis is frequently observed, both in consumers as well as workers in various industries. In this review, we provide an update on the use of MCI/MI and MI in cosmetics, highlighting certain aspects of MI; the use of excessive concentrations, the presence in some less familiar cosmetic products, and the association with unusual clinical manifestations. Read More

    Bioactivities of crude mucus proteins from Eudrilus eugeniae (African night crawler) and Perionyx excavatus (Blue worm).
    Eur Rev Med Pharmacol Sci 2017 Jan;21(2):361-368
    Department of Genetics, Faculty of Science, Kasetsart University, Bangkok, Thailand.
    Objective: This study aimed to investigate the enzymatic anti-oxidative, hemolytic and cytotoxic activities of crude mucus proteins from the two earthworms including Eudrilus eugeniae (African night crawler) and Perionyx excavatus (Blue worm).

    Materials And Methods: The bioactivities were determined by hemolytic activity, cytotoxic activity using HepG2 human hepatocellular carcinoma cells, L-929 mouse fibroblast and TK6 human lymphoblast cell lines and antioxidant activity.

    Results: The results indicated that the hemolytic activity of mucus proteins of P. Read More

    Plumbagin Suppresses α-MSH-Induced Melanogenesis in B16F10 Mouse Melanoma Cells by Inhibiting Tyrosinase Activity.
    Int J Mol Sci 2017 Feb 3;18(2). Epub 2017 Feb 3.
    Department of Biomedical Chemistry, College of Biomedical and Health Science, Konkuk University, Chungju 380-701, Korea.
    Recent studies have shown that plumbagin has anti-inflammatory, anti-allergic, antibacterial, and anti-cancer activities; however, it has not yet been shown whether plumbagin suppresses alpha-melanocyte stimulating hormone (α-MSH)-induced melanin synthesis to prevent hyperpigmentation. In this study, we demonstrated that plumbagin significantly suppresses α-MSH-stimulated melanin synthesis in B16F10 mouse melanoma cells. To understand the inhibitory mechanism of plumbagin on melanin synthesis, we performed cellular or cell-free tyrosinase activity assays and analyzed melanogenesis-related gene expression. Read More

    The cosmetic and dermatological potential of keratin hydrolysate.
    J Cosmet Dermatol 2017 Feb 6. Epub 2017 Feb 6.
    Department of Polymer Engineering, Faculty of Technology, Tomas Bata University in Zlin, Zlin, the Czech Republic.
    Background: Although keratin hydrolysates have become established as standard components in hair and nail cosmetics, studies on the moisturizing effects of keratin hydrolysates do not appear among contemporary literature.

    Objectives: To test if adding keratin hydrolysate into an ointment base increases hydration of the skin and improves skin barrier function, or diminishes trans-epidermal water loss.

    Methods: Formulations were prepared containing 2%, 4%, and 6% keratin hydrolysates (based on weight of the ointment base). Read More

    (Q)SAR tools for priority setting: A case study with printed paper and board food contact material substances.
    Food Chem Toxicol 2017 Feb 2;102:109-119. Epub 2017 Feb 2.
    Department of In Vitro Toxicology and Dermato-cosmetology, Vrije Universiteit Brussel, Laarbeeklaan 103, Brussels, Belgium.
    Over the last years, more stringent safety requirements for an increasing number of chemicals across many regulatory fields (e.g. industrial chemicals, pharmaceuticals, food, cosmetics, …) have triggered the need for an efficient screening strategy to prioritize the substances of highest concern. Read More

    In vivo testing of gold nanoparticles using the Caenorhabditis elegans model organism.
    Acta Biomater 2017 Feb 1. Epub 2017 Feb 1.
    Institut de Ciència de Materials de Barcelona, ICMAB-CSIC, Campus UAB, 08193 Bellaterra, Barcelona, Spain. Electronic address:
    Gold nanoparticles (AuNPs) are present in many man-made products and cosmetics and are also used by the food and medical industries. Tight regulations regarding the use of mammalian animals for product testing can hamper the study of the specific interactions between engineered nanoparticles and biological systems. Invertebrate models, such as the nematode Caenorhabditis elegans (C. Read More

    Purification, structural features, antioxidant and moisture-preserving activities of an exopolysaccharide from Lachnum YM262.
    Bioorg Med Chem Lett 2017 Mar 21;27(5):1225-1232. Epub 2017 Jan 21.
    Microbial Resources and Application Laboratory, School of Food Science and Engineering, Hefei University of Technology, Hefei 230009, China. Electronic address:
    A water-soluble exopolysaccharide, designated as LEP-2a, was isolated from Lachnum YM262 and purified by DEAE-Cellulose 52 and Sepharose CL-6B chromatographic columns. LEP-2a was a homogeneous polysaccharide, with a molecular weight of 1.52×10(5) Da. Read More

    Reconstructive surgery of the amputated ring finger.
    Int Orthop 2017 Feb 3. Epub 2017 Feb 3.
    Medical Center MEDEX, Republica de Panama 3065, San Isidro, Lima, Peru.
    Purpose: Loss of a fourth digit below the level of the proximal phalanx results in a weakened grip, loss of skilled movements, and the amputation stump is repeatedly traumatized. Transposition of an adjacent fifth digital ray can improve hand function and cosmetic appearance by closing the gap created by the missing digit. Digital ray amputation is not a commonly performed procedure. Read More

    Variability of skin pH after the use of different collagen gels.
    J Cosmet Dermatol 2017 Feb 3. Epub 2017 Feb 3.
    Department of Physiotherapy and Occupational Therapy, University of Physical Education in Wroclaw, Wroclaw, Poland.
    Background: Skin pH is an important parameter indicating the condition of the skin because imbalance can contribute to the development of skin problems and earlier aging. Individual skin pH depends on many factors such as hydration, sweating, sebum excretion, genetics, sex, and age. Additionally, it can be affected by exogenous factors such as cosmetics. Read More

    Macromolecular Antioxidants and Dietary Fiber in Edible Seaweeds.
    J Food Sci 2017 Feb 2;82(2):289-295. Epub 2017 Feb 2.
    Dept. of Metabolism and Nutrition, Inst. of Food Science, Technology and Nutrition (ICTAN-CSIC), Madrid, Spain.
    Seaweeds are rich in different bioactive compounds with potential uses in drugs, cosmetics and the food industry. The objective of this study was to analyze macromolecular antioxidants or nonextractable polyphenols, in several edible seaweed species collected in Chile (Gracilaria chilensis, Callophyllis concepcionensis, Macrocystis pyrifera, Scytosyphon lomentaria, Ulva sp. and Enteromorpha compressa), including their 1st HPLC characterization. Read More

    Progress in Microbial Carotenoids Production.
    Indian J Microbiol 2017 Mar 3;57(1):129-130. Epub 2017 Jan 3.
    0000 0004 0532 8339grid.258676.8Department of Bioresources and Food Science, College of Life and Environmental Sciences, Konkuk University, Seoul, 143-701 Korea.
    Carotenoids are versatile isoprenoids pigments, play a vital role in the cellular system, starting from antioxidant to gene regulation. Carotenoids are widely used in food, nutraceuticals, and cosmetics owing to their vitamin A, antioxidant and anticancer activities. The demand of carotenoids in various sectors has triggered the research to explore a commercially viable and environmentally friendly production. Read More

    Review on cell models to evaluate the potential antioxidant activity of polysaccharides.
    Food Funct 2017 Feb 1. Epub 2017 Feb 1.
    State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China.
    Owing to various health functions, natural polysaccharides are becoming a kind of popular dietary nutritional supplement. At present, the occurrence of many chronic diseases is closely related to excessive reactive oxygen species (ROS). Note that polysaccharides with anti-oxidative activity have been paid significant attention as medicines, cosmetics, and food. Read More

    Oleofoams: Properties of Crystal-Coated Bubbles from Whipped Oleogels-Evidence for Pickering Stabilization.
    Langmuir 2017 Feb 31;33(6):1563-1575. Epub 2017 Jan 31.
    Nestlé Research Center , Vers-chez-les-Blanc, CH-1000 Lausanne 26, Switzerland.
    Interfacially stabilized nonaqueous lipid-based foams, which we name here oleofoams, are rarely encountered as opposed to the large number of aqueous foams stabilized by molecular or particulate emulsifiers. There is no case well described in the literature with a convincing characterization of the interfacial contribution to oleofoam stability. Methods for filling this gap are described here, which reach out to a large part of the lipid phase diagram. Read More

    Comparison of protocols measuring diffusion and partition coefficients in the stratum corneum.
    J Appl Toxicol 2017 Jan 31. Epub 2017 Jan 31.
    L'Oreal Research & Innovation, 1, avenue Eugène Schueller, 93601, Aulnay-sous-Bois, France.
    Partition (K) and diffusion (D) coefficients are important to measure for the modelling of skin penetration of chemicals through the stratum corneum (SC). We compared the feasibility of three protocols for the testing of 50 chemicals in our main studies, using three cosmetics-relevant model chemicals with a wide range of logP values. Protocol 1: SC concentration-depth profile using tape-stripping (measures KSC/v and DSC /HSC(2) , where HSC is the SC thickness); Protocol 2A: incubation of isolated SC with chemical (direct measurement of KSC/v only) and Protocol 2B: diffusion through isolated SC mounted on a Franz cell (measures KSC/v and DSC /HSC(2) , and is based on Fick's laws). Read More

    Development of herbal disinfectants formulation for mopping households and its antibacterial activity.
    Nat Prod Res 2017 Jan 30:1-4. Epub 2017 Jan 30.
    a Sadbhav SRISTI Sanshodhan Natural Products Laboratory , SRISTI , Ahmedabad , India.
    There are many household products like detergents, disinfectants, stain removers and cosmetics releasing chemicals that may be harmful to human health as well as cause hazardous effect on environment. Global world is now focusing on use of herbal products. They are eco-friendly and more suitable to household applications than chemicals. Read More

    Use of mixture design in drug-excipient compatibility determinations: Thymol nanoparticles case study.
    J Pharm Biomed Anal 2017 Apr 22;137:196-203. Epub 2017 Jan 22.
    Laboratory of Food, Drug and Cosmetics (LTMAC), School of Health Sciences, University of Brasília, Brasília, DF, Brazil. Electronic address:
    The objective of this work was to access thymol-excipient compatibility using an alternative protocol of mixture design subsidizing the development of nanostructures lipid carriers containing this drug. Simultaneous DTA-TG analyses associated with infrared spectroscopy were performed according to simplex centroid mixture designs with three components. Two designs were used: the design A containing stearic acid (SA), soybean lecithin (LC), and sodium taurodeoxycholate (TAU) and the design B, where TAU was replaced by polysorbate 80 (P80). Read More

    Assessment of parabens and ultraviolet filters in human placenta tissue by ultrasound-assisted extraction and ultra-high performance liquid chromatography-tandem mass spectrometry.
    J Chromatogr A 2017 Mar 18;1487:153-161. Epub 2017 Jan 18.
    Instituto de Investigación Biosanitaria (ibs. GRANADA), Hospitales Universitarios de Granada, Spain; CIBER en Epidemiología y Salud Pública (CIBERESP), Spain; Departamento de Radiología y Medicina Física, Universidad de Granada, Granada, Spain.
    Increasing concerns have been raised over recent decades about human exposure to Endocrine Disrupting Chemicals (EDCs), especially about their possible effects on embryo, foetus, newborn, and child. Parabens (PBs) and ultraviolet filters (UV-filters) are prevalent EDCs widely used as additives in cosmetics and personal care products (PCPs). The objective of this study was to determine the presence of four PBs and ten UV-filters in placental tissue samples using a novel analytical method based on ultrasound-assisted extraction (UAE) and ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS). Read More

    1 OF 1060