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Contact Dermatitis 2020 Jul 3. Epub 2020 Jul 3.

Department of Dermatology, Toho University School of Medicine, Tokyo, Japan.

J Photochem Photobiol B 2020 Jun 24;209:111943. Epub 2020 Jun 24.

Amrita Centre for Industrial Research &Innovation, Amrita School of Engineering, Coimbatore 641112, Amrita Vishwa Vidyapeetham, India; Departmentof Chemical Engineering & Materials Science, Amrita School of Engineering, Coimbatore 641112, Amrita Vishwa Vidyapeetham, India. Electronic address:

In modern society, the use of cosmetics has increased extensively; unfortunately, so-called several toxic metal salts are present as the colorant or filler in cosmetics. The ferrous ion (Fe) is one of the metal ions used in cosmetics as a colorant. Ferrous ion (Fe) is a vital component in live cells. Read More

J Environ Sci Health A Tox Hazard Subst Environ Eng 2020 Jul 2:1-8. Epub 2020 Jul 2.

Radiation Research of Polymer chemistry Department, National Center for Radiation Research and Technology, Egyptian Atomic Energy Authority, Cairo, Egypt.

Recently, Silver nanoparticles (AgNPs) have become widely applied nanomaterial in human contacting areas such as cosmetics, food and medicine due to their antibacterial property. On the other hand, surfactants are essential ingredient of several industrial and consumer formulations. Based on these important applications, the current research was aimed to carry out the synthesis and characterization of Tween 80 capped silver nanoparticles (T80-AgNPs) using gamma radiation reduction method. Read More

J Indian Soc Pedod Prev Dent 2020 Apr-Jun;38(2):171-176

Department of Pedodontics and Preventive Dentistry, Vishnu Dental College, Bhimavaram, Andhra Pradesh, India.

Background: Pulpectomy is a routine practice in children with pulpal and periapical infections, the success of which depends on the elimination of bacteria from the root canals. Propolis, a natural product with proven antibacterial and anti-inflammatory properties when mixed with zinc oxide powder as root canal filling material, it could provide good success in endodontic therapy of primary teeth.

Aim: The aim was to evaluate and compare the clinical effectiveness of zinc oxide-propolis mixture with zinc oxide eugenol (ZOE) as root canal filling material in nonvital primary molars. Read More

J Indian Soc Pedod Prev Dent 2020 Apr-Jun;38(2):152-157

Department of Pediatric and Preventive Dentistry, Kannur Dental College, Kannur, Kerala, India.

Background: Early childhood caries (ECC) is an aggressive, destructive form of dental caries that affects the children younger than 6 years of age. Candida is known to increase the adherence of Streptococcus mutans to the oral biofilm and produce acids that cause tooth demineralization.

Aim Of The Study: To evaluate the efficacy of six commercially available children's toothpaste on clinical isolates of Candida albicans obtained from ECC patients. Read More

Biomolecules 2020 Jun 29;10(7). Epub 2020 Jun 29.

CBIOS-Research Center for Biosciences & Health Technologies, Universidade Lusófona, 1749-024 Lisboa, Portugal.

Due to the sustainable organic matter bioconversion process used as substrate for its development, the (Linnaeus) larvae biomass is considered a source of compounds with high aggregate value and quite a promising market. The materials that can be extracted from larvae have opened the door to a diverse new field of ingredients, mainly for the feed and food industry, but also with potential applicability in cosmetics. In this review we succinctly describe the larval development and rearing cycle, the main compounds identified from different types of extractions, their bioactivities and focus on possible applications in cosmetic products. Read More

Int J Mol Sci 2020 Jun 29;21(13). Epub 2020 Jun 29.

Department of Medicinal Biosciences, Research Institute for Biomedical & Health Science, College of Biomedical and Health Science, Konkuk University, 268 Chungwon-daero Chungju-si 27478, Korea.

Apigenin (4',5,7-trihydroxyflavone, flavonoid) is a phenolic compound that is known to reduce the risk of chronic disease owing to its low toxicity. The first study on apigenin analyzed its effect on histamine release in the 1950s. Since then, anti-mutation and antitumor properties of apigenin have been widely reported. Read More

Stomatologiia (Mosk) 2020 ;99(3):11-17

Privolzhsky Research Medical University of the Ministry of Health of the Russian Federation, Nizhniy Novgorod, Russia.

The aim of the study was to study clinical and histological changes in the treatment of discoloration using different systems for professional tooth whitening. The study involved 76 patients. Patients of group 1 had their teeth whitened by the Amazing White Universal Extra photochemical activation system, and group 2 had their teeth whitened by the Beyond Polus system. Read More

Contact Dermatitis 2020 Jul 1. Epub 2020 Jul 1.

Park Nicollet Contact Dermatitis Clinic, Minneapolis, Minnesota.

Drug Des Devel Ther 2020 9;14:2275-2285. Epub 2020 Jun 9.

Department of Gastroenterology, Putuo People's Hospital, Tongji University School of Medicine, Shanghai 200060, People's Republic of China.

Astaxanthin is a carotenoid derived from oxygen-containing non-vitamin A sources and is mainly obtained from marine organisms. Studies have demonstrated that astaxanthin is a natural antioxidant product and it is widely used in the fields of medicine, health-care products and cosmetics. Studies have shown that astaxanthin has important preventive and therapeutic effects on liver fibrosis, non-alcoholic fatty liver, liver cancer, drug and ischemia-induced liver injury, and its mechanism is related to antioxidant and anti-inflammatory activities, and the regulation of multiple signaling pathways. Read More

Materials (Basel) 2020 Jun 28;13(13). Epub 2020 Jun 28.

Department of Biomaterials and Cosmetics Chemistry, Faculty of Chemistry, Nicolaus Copernicus University in Toruń, Gagarin 7, 87-100 Toruń, Poland.

Currently, packaging materials constitute a group of the most commonly used products. Natural polymers are widely tested as potential packaging materials to replace traditional plastics. Sodium alginate is eco-friendly and reveals effective film-forming properties whereas tannic acid has been proposed as a sodium alginate cross-linker. Read More

Comb Chem High Throughput Screen 2020 Jun 30. Epub 2020 Jun 30.

Sivas Cumhuriyet University, Faculty of Pharmacy, Department of Pharmaceutical Toxicology . Turkey.

Aim And Scope: Due to the serious toxicological risks and their widespread use, quantitative determination of phthalates in cosmetic products have importance for public health. The aim of this study was to develop a validated simple, rapid and reliable high-performance liquid chromatography (HPLC) method for the determination of phthalates which are; dimethyl phthalate (DMP), diethyl phthalate (DEP), benzyl butyl phthalate (BBP), di-n-butyl phthalate (DBP), di(2- ethylhexyl) phthalate (DEHP), in cosmetic products and to investigate to these phthalate (PHT) levels in 48 cosmetic products marketing in Sivas, Turkey.

Materials And Methods: Separation was achieved by a reverse-phase ACE-5 C18 column (4. Read More

Adv Exp Med Biol 2020 ;1250:3-13

Department of BIN Convergence Technology, Department of Polymer Nano Science & Technology and Polymer BIN Research Center, Jeonbuk National University, Jeonju, South Korea.

Collagen is an important component that makes 25-35% of our body proteins. Over the past decades, tissue engineers have been designing collagen-based biocompatible materials and studying their applications in different fields. Collagen obtained from cattle and pigs has been mainly used until now, but collagen derived from fish and other livestock has attracted more attention since the outbreak of mad cow disease, and they are also used as a raw material for cosmetics and foods. Read More

Pharmaceutics 2020 Jun 24;12(6). Epub 2020 Jun 24.

Department of Forensic Medicine, Faculty of Medicine, Medical University of Gdańsk, ul. Dębowa 23, 80-204 Gdańsk, Poland.

Cyclic methylsiloxanes D4, D5, D6 (also called cyclic silicones) are widely used in various dermatological products and cosmetics, both for children and adults. As a result of their unique physicochemical properties, the production of cyclic methylsiloxanes has greatly increased over the last few years, which has resulted in increased exposure to mankind. The validated quantitative for gas chromatography-flame ionization detector (GC-FID) analysis with using the transdermal diffusion system with vertical Franz cells demonstrated that ex vivo human skin is not a barrier to cyclic siloxanes. Read More

Int J Biol Macromol 2020 Jun 26. Epub 2020 Jun 26.

Department of Marine Bio-Food Sciences, Chonnam National University, Yeosu 59626, Republic of Korea; Department of Food Technology and Nutrition, Chonnam National University, Yeosu 59626, Republic of Korea. Electronic address:

Ultraviolet B (UVB) can induce oxidative damage to outermost layers of skin causing suntans, sunburns, and, in severe cases, blisters leading to photoaging. Low molecular weight (MW) fucoidan is renowned for possessing enhanced antioxidant activities. The present study discloses the use of step gradient ethanol precipitation in refining fucoidan fractions (SSQC1-SSQC4) from Sargassum siliquastrum and evaluation of their UVB-protective effects in human HaCaT keratinocytes. Read More

Water Sci Technol 2020 Mar;81(6):1296-1307

Department of Chemistry, College of Natural Sciences, Yeungnam University, Gyeongsan, Gyeongbuk 38541, Republic of Korea.

Methylene blue (MB) dye is the most common harmful, toxic, and non-biodegradable effluent produced by the textile industries. The present study investigates the effect of zinc oxide (ZnO) nanoparticles (NPs) and Ag-Ni doped ZnO NPs on the performance of photocatalytic degradation of MB dye. Pure ZnO and Ag-Ni doped ZnO NPs are synthesized using the co-precipitation method. Read More

J Tissue Eng Regen Med 2020 Jun 26. Epub 2020 Jun 26.

Sunny BioDiscovery, Santa Paula, CA, USA.

The ability to control facial skin physiology and appearance through the oral mucosa (transbuccally) is largely unexplored. Here, a hypothesis was tested that transbuccal delivery of fat tissue-supportive actives may trigger beneficial cosmetic responses at the level of the skin. First, the importance of the fat tissue for skin structure and function was established by comparative analysis of human biopsies cultured defatted or in the presence of hypodermis, using macroscopic observation, qPCR and histochemistry. Read More

Evid Based Dent 2020 06;21(2):42-43

Senior Lecturer / Consultant in Restorative Dentistry, Centre for Public Health, Queen's University Belfast, UK.

This narrative review describes the existing body of evidence supporting the potential role of oral rinses in preventing the transmission of SARS-CoV2. Multiple sources were searched for evidence including PubMed, Researchgate and Google Scholar. References that were identified were then investigated further to find additional source material and the original primary research. Read More

Ear Hear 2020 Jun 24. Epub 2020 Jun 24.

Ear Science Institute Australia, Subiaco, Australia.

Objectives: To explore the factors influencing the uptake of cochlear implants in adults, determine the impact of each factor, and to conceptualize the journey to implantation from a multistakeholder perspective.

Design: Concept mapping was used to integrate input from multiple stakeholders, each with their own experience and expertise. This mixed participatory method collects qualitative and quantitative data collection and enables further quantitative analysis. Read More

Contact Dermatitis 2020 Jun 25. Epub 2020 Jun 25.

Vilnius University Faculty of Medicine, Institute of Clinical Medicine, Vilnius, Lithuania.

Background: The application of preparations containing food allergens can cause percutaneous sensitisation and provocation. The prevalence of food allergens in children's cosmetics is unknown.

Objectives: To analyse the prevalence of food allergens in skincare products marketed for children and its association with marketing claims and product price. Read More

Gen Thorac Cardiovasc Surg 2020 Jun 25. Epub 2020 Jun 25.

Department of Cardio Thoracic and Vascular Surgery, U.N.Mehta Institute of Cardiology and Research Center, Civil Hospital Campus, Asarwa, Ahmedabad, 380016, Gujarat, India.

Background: Minimal Invasive Direct Coronary Artery Bypass Surgery (MIDCAB) is becoming popular and an important armamentarium for cardiac surgeons. We aimed to evaluate the result of MIDCAB total arterial revascularization.

Methods: We have evaluated 216 patients who underwent MIDCAB multivessel total arterial revascularization through a left anterolateral mini thoracotomy. Read More

Front Bioeng Biotechnol 2020 10;8:575. Epub 2020 Jun 10.

Postgraduate Program in Translational Biomedicine, University of Grande Rio, Duque de Caxias, Brazil.

Titanium dioxide nanoparticles (TiO NPs) are regularly used in sunscreens because of their photoprotective capacity. The advantage of using TiO on the nanometer scale is due to its transparency and better UV blocking efficiency. Due to the greater surface area/volume ratio, NPs become more (bio)-reactive giving rise to concerns about their potential toxicity. Read More

Funct Plant Biol 2020 Jun 26. Epub 2020 Jun 26.

The herbal orchid Bletilla striata (Thunb.) Rchb.f. Read More

J Biomater Sci Polym Ed 2020 Jul 3:1-16. Epub 2020 Jul 3.

Petrochemical and Polymer Program, School of Engineering and Technology, Walailak University, Nakhon Si Thammarat 80160, Thailand.

Bacterial cellulose (BC) has been used in the combination with molecularly imprinted polymer (MIP) for controlled-release drug delivery. In the present study, the molecular imprinting was directly performed on BC to avoid the use of synthetic materials for sustained-release of quercetin, which was used as the template molecule. The phase inversion method was successfully used to prepare molecularly imprinted BC (MI-BC). Read More

Cutan Ocul Toxicol 2020 Jun 25:1-42. Epub 2020 Jun 25.

Integrated Laboratory Systems, Inc., PO Box 13501, Research Triangle Park, NC 27709, USA.

OptiSafe is an test method that identifies potential eye irritants based on macromolecular damage following test chemical exposure. The OptiSafe protocol includes a pre-screen assessment that identifies test chemicals that are outside the applicability domain of the test method and thus determines the optimal procedure. We assessed the usefulness and limitations of the OptiSafe test method for identifying chemicals not requiring classification for ocular irritation (i. Read More

Int J Biol Macromol 2020 Jun 22;162:853-865. Epub 2020 Jun 22.

School of Biosciences and Technology, Vellore Institute of Technology, Vellore 632014, Tamil Nadu, India. Electronic address:

Exopolysaccharides (EPS) are extracellular macromolecules excreted as tightly bound capsule or loosely attached slime layer in microorganisms. They play most prominent role against desiccation, phagocytosis, cell recognition, phage attack, antibiotics or toxic compounds and osmotic stress. In the last few decades, natural polymers have gained much attention among scientific communities owing to their therapeutic potential. Read More

J Contemp Dent Pract 2020 Apr 1;21(4):396-399. Epub 2020 Apr 1.

Department of Microbiology, Faculty of Pharmacy, Al-Azhar University Cairo, Egypt.

Aim: The aim of this study was to evaluate and compare the antibacterial effect of 0.5% metronidazole, 2% chlorhexidine, and normal saline irrigant solutions against bacteria in the treatment of root canals of primary anterior teeth.

Materials And Methods: This study was carried out on sixty nonvital primary anterior teeth of Egyptian children diagnosed with (early childhood caries) ECC. Read More

J Cosmet Dermatol 2020 Jun 24. Epub 2020 Jun 24.

Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Frederico II, Naples, Italy.

Background: Glycolic acid (GA) is an effective way of reversing the signs of age and photodamage. GA enhances desquamation of the stratum corneum and induces biological responses that can help restore skin's integrity. GA can, however, cause irritation, especially when its concentration is high, and its pH is low. Read More

Probiotics Antimicrob Proteins 2020 Jun 24. Epub 2020 Jun 24.

Department of Dairy, Fat and Cosmetics, University of Chemistry and Technology, Technická 5, 166 28, Prague 6, Czech Republic.

Lactobacilli in the vaginal tract are essential to protect against microbial infections. We therefore focused on isolating vaginal lactobacilli from pregnant women and testing their functional properties. Lactobacilli were isolated from 50 vaginal swabs and the purified isolates were identified by MALDI-TOF MS. Read More

Small 2020 Jun 23:e2002716. Epub 2020 Jun 23.

John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, 02138, USA.

Co-precipitation is generally refers to the co-precipitation of two solids and is widely used to prepare active-loaded nanoparticles. Here, it is demonstrated that liquid and solid can precipitate simultaneously to produce hierarchical core-shell nanocapsules that encapsulate an oil core in a polymer shell. During the co-precipitation process, the polymer preferentially deposits at the oil/water interface, wetting both the oil and water phases; the behavior is determined by the spreading coefficients and driven by the energy minimization. Read More

J Cosmet Dermatol 2020 Jun 23. Epub 2020 Jun 23.

Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia.

Background: Although cosmetic products such as sunscreens and moisturizers are generally considered safe, they can be less effective or harmful if used improperly. Thus, pharmacist's awareness about cosmeceuticals is pivotal in counseling about the ingredients and the proper use of such products.

Objective: To evaluate the awareness level of community pharmacists regarding cosmetic products particularly sunscreens and moisturizers in Jeddah, Saudi Arabia. Read More

BMC Chem 2020 Dec 19;14(1):41. Epub 2020 Jun 19.

Laboratory for Preservation Technology and Enzyme Inhibition Studies, Department of Pharmaceutical Sciences, Faculty of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak, Haryana India.

Background: Preservatives have to be added in food, pharmaceuticals and cosmetics products to maintain their shelf life. However, the existing chemical based preservatives have been associated with severe side effects that compel the researchers to find better safe preservatives based on natural products. G-6-P synthase is an important enzyme for bacterial and fungal cell wall synthesis and offers as a potential target to find better G-6-P synthase inhibitors based antimicrobial compounds. Read More

Mar Drugs 2020 Jun 19;18(6). Epub 2020 Jun 19.

Department of Biological Sciences, School of Science & Technology, Sunway University, Bandar Sunway 47500, Selangor Darul Ehsan, Malaysia.

Cosmetics are widely used by people around the world to protect the skin from external stimuli. Consumer preference towards natural cosmetic products has increased as the synthetic cosmetic products caused adverse side effects and resulted in low absorption rate due to the chemicals' larger molecular size. The cosmetic industry uses the term "cosmeceutical", referring to a cosmetic product that is claimed to have medicinal or drug-like benefits. Read More

Plants (Basel) 2020 Jun 19;9(6). Epub 2020 Jun 19.

Institute of Bast Fiber Crops and Center of Southern Economic Crops, Chinese Academy of Agricultural Sciences, Changsha 410205, China.

Fiber crops are an important group of economic plants. Traditionally cultivated for fiber, fiber crops have also become sources of other materials such as food, animal feed, cosmetics and medicine. Asia and America are the two main production areas of fiber crops in the world. Read More

J Cosmet Dermatol 2020 Jun 23. Epub 2020 Jun 23.

Department of Aesthetic Medicine, Medical University of Białystok, Białystok, Poland.

Background: COVID-19 pandemic influences a lot of aspects of human life. Particularly, hygienic habits are affected.

Objectives: Changes in washing and cosmetic standards during the pandemic toward the past are in the focus of our interest. Read More

Mar Drugs 2020 Jun 18;18(6). Epub 2020 Jun 18.

Laboratoire de Pharmacie industrielle et de Cosmétologie, Faculté de Pharmacie, Université de Nantes, MMS, EA2160, 61112-44035 Nantes, France.

Marine resources exist in vast numbers and show enormous diversity. As a result, there are likely many possible applications for marine molecules of interest in the cosmetic industry, whether as excipients or additives, but especially as active substances. It is possible to obtain extracts from active substances; for example, quite a few algae species can be used in moisturizing or anti-ageing products. Read More

Food Chem 2020 May 29;330:127173. Epub 2020 May 29.

LABEX/FEA (Extraction Laboratory/Faculty of Food Engineering), ITEC (Institute of Technology), UFPA (Federal University of Para), Rua Augusto Corrêa S/N, Guamá, 66075-900 Belém, PA, Brazil. Electronic address:

Pleurotus ostreatus is an edible mushroom with pharmacological potential, due to its metabolites, mainly polysaccharides. On here, the development of a new methodology for the recovery of extract rich in antioxidant polysaccharide was reported. The extracts were characterized, evaluated for antioxidant activity in vitro and in cell models and cytotoxicity. Read More

J Pept Sci 2020 Jul 21;26(7):e3255. Epub 2020 Jun 21.

Department of Oncology, Laboratory of Structural Biology, NHC Key Laboratory of Cancer Proteomics, Xiangya Hospital, Central South University, Changsha, China.

Proliferation of Propionibacterium acnes (P. acnes) is one of the main pathogenetic mechanisms of acne. Antimicrobial peptides with low-drug resistance and nonresidual are potential anti-acne agents. Read More

J Mass Spectrom 2020 Sep;55(9):e4526

Dipartimento di Chimica e Tecnologie Chimiche, Università della Calabria, Via P. Bucci Cubo 12/C, Arcavacata di Rende, I87036, Italy.

A fast methodology for the assay of parabens in drug and cosmetic preparations has been presented. The procedure developed is based on paper spray tandem mass spectrometry and isotope dilution approach. For each investigated paraben, the corresponding labeled standard has been used in order to improve the accuracy and reproducibility of the analyses. Read More

Food Sci Nutr 2020 Jun 27;8(6):2642-2651. Epub 2020 Apr 27.

Key Laboratory of Tibetan Medicine Research Northwest Institute of Plateau Biology Chinese Academy of Sciences Xining China.

The ultrasonic extraction (UE) technology, possessed the advantages of effective, energy-saving, and environmental-friendly, was applied to extract the anthocyanin from (LR). The extraction parameters of UE were optimized by response surface methodology (RSM) with Box-Behnken design (BBD). Anthocyanin composition in LR fruits grown in China was systematically identified and quantified by HPLC-ESI-MS. Read More

Pharm Pract (Granada) 2020 Apr-Jun;18(2):1910. Epub 2020 Jun 2.

PhD. Laboratory of Nanosystems and Drug Delivery Devices (NanoSYS), School of Pharmacy, Federal University of Goiás. Goiânia, GO (Brazil).

Background: Although a highly common practice in hospital care, tablet splitting can cause dose variation and reduce drug stability, both of which impair drug therapy.

Objective: To determine the overall prevalence of tablet splitting in hospital care as evidence supporting the rational prescription of split tablets in hospitals.

Methods: Data collected from inpatients' prescriptions were analyzed using descriptive statistics and used to calculate the overall prevalence of tablet splitting and the percentage of split tablets that had at least one lower-strength tablet available on the market. Read More

Carbohydr Polym 2020 Aug 14;242:116389. Epub 2020 May 14.

Department of Food Science and Technology, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200240, China. Electronic address:

Alginate and pectin are emblematic natural polyuronates that have been widely used in food, cosmetics and medicine. Ca-dependent gelation is one of their most important functional properties. The gelation mechanisms of alginate and pectin, known as egg-box model, were believed to be basically the same, because their Ca-binding sites show a mirror symmetric conformation. Read More

J Toxicol Environ Health A 2020 Jun;83(11-12):470-484

Department of Pharmacy, College of Pharmacy, Dankook University , Cheonan, Chungnam, Republic of Korea.

The aim of this study was to determine the effects of anti-wrinkle and skin-whitening of fermented black ginseng (FBG) in human subjects and to examine underlying biochemical mechanisms of action. A clinical study was performed to evaluate efficacy and safety using a 1% FBG cream formulation. Twenty-three subjects were recruited and instructed to apply control or FBG creams each on half of their face twice daily for 8 weeks. Read More

Regul Toxicol Pharmacol 2020 Jun 17:104699. Epub 2020 Jun 17.

Posgraduate Program in Dentistry, Piracicaba Dental School, University of Campinas, FOP/UNICAMP, 13414-903, Piracicaba, SP, Brazil; Faculty of Pharmaceutical Sciences, University of Campinas, FCF/UNICAMP, 13081-970, Campinas, SP, Brazil. Electronic address:

Natural and synthetic dyes are widely used in foodstuff, medicines and cosmetics industries to enhance and/or restore the color of the final products. This study aimed to evaluate the safety of oral consumption of one carotenoids and anacardic acids-enriched extract (CAE), obtained by green extraction from cashew apple residue fibers, a byproduct of the cashew juice industry. Presenting intense yellow color, CAE could be proposed as a new natural dye. Read More

J Cosmet Dermatol 2020 Jun 20. Epub 2020 Jun 20.

Department of Dermatology, Second Xiangya Hospital, Central South University, Changsha, China.

Background: Inflammatory skin diseases include a variety of skin diseases, such as seborrheic dermatitis, acne, atopic dermatitis, psoriasis and so on, which are more common and tend to have a significant impact on patients' quality of life. Inflammatory skin diseases often result in physical or psychological distress; however, the pathogenesis of these diseases have not been clearly elucidated. Many factors are involved in the pathogenesis of inflammatory skin diseases, including heredity, environment, immunity, epidermal barrier, mental disorders, infection and so on. Read More

Nat Commun 2020 Jun 19;11(1):3120. Epub 2020 Jun 19.

The Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, 214122, Wuxi, China.

Hyaluronan is widely used in cosmetics and pharmaceutics. Development of robust and safe cell factories and cultivation approaches to efficiently produce hyaluronan is of many interests. Here, we describe the metabolic engineering of Corynebacterium glutamicum and application of a fermentation strategy to manufacture hyaluronan with different molecular weights. Read More

Foods 2020 Jun 16;9(6). Epub 2020 Jun 16.

Department Agro-Bio-Chem, University of Liege-Gembloux Agro-Bio Tech, Passage des Déportés 2, 5030 Gembloux, Belgium.

The cultivation of the date palm ( L.) is the main activity and source of livelihood for people from arid and semiarid regions of the world. Date production is increasing every year. Read More

Chemosphere 2020 Oct 17;256:127094. Epub 2020 May 17.

Department of Civil and Environmental Engineering, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong.

Sulfite-based photocatalysis has been recently employed as a promising technology for the treatment of organic pollutants via the generation of reactive radicals. In this contribution, the effect of wastewater matrix constituents and toxicity evaluation were systematically investigated in the Fe impregnated N-doped TiO (FeN-TiO)/sulfite/visible LED (Vis LED) process in the presence of diphenamid (DPA) as a model organic pollutant. The results showed that the presence of HCO, SO, NO, and F had no detrimental effect on DPA degradation. Read More

Allergy 2020 Jun 19. Epub 2020 Jun 19.

Department of Dermatology, Valencia University General Hospital. Valencia, Valencia, Spain.

Parabens are para-hydroxybenzoic acid esters that have been used for almost 100 years as preservatives in cosmetics, drugs and foods. Sensitization to parabens was first described in the 1940s, and these compounds were subsequently included in the standard patch test batteries. Data based on weak scientific evidence have attributed parabens with carcinogenic, infertility and endocrine disruption effects. Read More

Pigment Cell Melanoma Res 2020 Jun 18. Epub 2020 Jun 18.

Department of Dermatology, Faculty of Medicine, Yamagata University, Yamagata, Japan.

Racemic RS-4-(4-hydroxyphenyl)-2-butanol (rhododendrol; trade name: Rhododenol [RD]), which is used in topical skin-lightening cosmetics, was unexpectedly reported in Japan to induce leukoderma or vitiligo called RD-induced leukoderma (RIL) after repeated application. To our knowledge, no studies have investigated chemical-induced vitiligo pathogenesis on a genome-wide scale. Here, we conducted a genome-wide association study (GWAS) for 147 cases and 112 controls. Read More