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    Female Sexual Dysfunction Among Muslim Women: Increasing Awareness to Improve Overall Evaluation and Treatment.
    Sex Med Rev 2018 Apr 17. Epub 2018 Apr 17.
    Center for Gynecology and Cosmetics, Obstetrics and Gynecology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. Electronic address:
    Introduction: Muslim women are an increasingly underserved population in the United States and worldwide. Diagnosis and treatment of female sexual dysfunction bring unique challenges because of the conservative nature of those practicing the religion. Several cultural and religious codes of conduct affect sexual behavior and the dysfunction that can ensue. Read More

    Antiproliferative and Antioxidant Activities of Two Extracts of the Plant Species L.
    Medicines (Basel) 2018 Apr 20;5(2). Epub 2018 Apr 20.
    Laboratoire de Phytochimie et Analyses Physico-Chimiques et Biologiques, Université Mentouri de Constantine, Route de Aïn El Bey, Constantine 25000, Algeria.
    These days, the desire for naturally occurring antioxidants has significantly increased, especially for use in foodstuffs, cosmetics, and pharmaceutical products, to replace synthetic antioxidants that are regularly constrained due to their carcinogenicity. : The study in hand aimed to appraise the antioxidant effect of two extracts using reducing power, anti-peroxidation, and DPPH (1,1 Diphenyl 2 Pycril Hydrazil) scavenging essays, in addition to the anticancer activity against two tumor cell lines, namely C6 (rat brain tumor)cells, and Hela (human uterus carcinoma)cell lines. : The results indicated that the ethyl acetate extract exhibited antiradical activity of 29. Read More

    Validation of an In Vitro Sun Protection Factor (SPF) method in blinded ring-testing.
    Int J Cosmet Sci 2018 Apr 20. Epub 2018 Apr 20.
    Procter& Gamble, Greater London Innovation Centre, Egham, UK.
    Objective: The objective of this work was to investigate the utility of a new in vitro SPF test method in blinded ring-testing, against new ISO acceptance criteria.

    Methods: 24 blinded, commercial, emulsion-type, primary sunscreen products, covering the full range of labelled SPF in Europe (SPF6 - 50+), were tested by 3 test institutes using the current ISO24444:2010 In Vivo SPF Test Method and simultaneously by 3 separate test laboratories using a new candidate in vitro SPF test method, developed under the leadership of Cosmetics Europe (CE). The resulting relationship between in vitro SPF and in vivo SPF values was then compared with acceptance criteria developed recently by the International Standards (ISO) TC217 / WG7 Sun Protection Test Methods Working Group. Read More

    Kinetic resolution of N-acetyl-DL-alanine methyl ester using immobilized Escherichia coli cells bearing recombinant esterase from Bacillus cereus.
    Chirality 2018 Apr 20. Epub 2018 Apr 20.
    Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, China.
    D-alanine is widely used in medicine, food, additives, cosmetics, and other consumer items. Esterase derived from Bacillus cereus WZZ001 exhibits high hydrolytic activity and stereoselectivity. In this study, we expressed the esterase gene in Escherichia coli BL21 (DE3). Read More

    Inedible saccharides: a platform for CO capturing.
    Chem Sci 2018 Feb 5;9(5):1088-1100. Epub 2018 Jan 5.
    Department of Chemistry , The Hashemite University , P. O. Box 150459 , Zarqa 13115 , Jordan . Email:
    The economic viability of eco-friendly and renewable materials promotes the development of an alternative technology for climate change mitigation. Investigations reported over the past few years have allowed understanding the mechanism of action for a wide spectrum of saccharides toward carbon dioxide (CO), in terms of reactivity, reversibility, stability and uptake. Exploiting bio-renewables, , inedible saccharides, to reduce the anthropogenic carbon footprint upon providing a sustainable and promising technology that is of interest to different groups of scientists, to overcome demerits associated with the current state-of-the-art aqueous amine scrubbing agents, following a "green chemistry guideline", by employing materials with properties relevant to the environment toward sustainable development. Read More

    Bio-Based Strategies for Producing Glycosaminoglycans and Their Oligosaccharides.
    Trends Biotechnol 2018 Apr 16. Epub 2018 Apr 16.
    Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, 214122, China.
    Glycosaminoglycans (GAGs) and their oligosaccharides have attracted extensive attention because of their wide applications in cosmetics, health, and clinical treatment of, for example, thrombus, osteoarthritis, rheumatism, and cancer. Compared to conventional preparation approaches, bio-based strategies for producing GAGs and their oligosaccharides are more promising because they avoid cross-infection of human and animal diseases, use green production processes, and can precisely control the degree of sulfation and molecular weight. This review summarizes recently developed bio-based strategies for producing GAGs, highlighting in particular enzymatic, metabolic engineering, and synthetic biology strategies. Read More

    A miniaturized monolith-MWCNTs-COOH multi-stir-rod microextractor device for trace parabens determination in cosmetic and personal care products.
    Talanta 2018 Jul 14;184:429-436. Epub 2018 Mar 14.
    Trace Analysis and Biosensor Research Center, Prince of Songkla University, Hat Yai, Songkhla 90112, Thailand; Center of Excellence for Innovation in Chemistry, Faculty of Science, Prince of Songkla University, Hat Yai, Songkhla 90112, Thailand; Department of Chemistry, Faculty of Science, Prince of Songkla University, Hat Yai, Songkhla 90112, Thailand. Electronic address:
    A portable and simple microextractor device was constructed by aligning six miniaturized multi-stir-rod microextractors. Each microextractor was prepared from rod-like multiwalled carbon nanotubes functionalized with a carboxylic group (MWCNTs-COOH) in composite monoliths that were bundled together and connected to a small DC motor. Using six of these microextractors, the device could extract six samples at the same time. Read More

    Combination of Ultrasound-Assisted Cloud-Point Extraction with Spectrophotometry for Extraction, Preconcentration, and Determination of Low Levels of Free Formaldehyde from Cosmetic Products.
    J AOAC Int 2018 Apr 19. Epub 2018 Apr 19.
    University of Cumhuriyet, Faculty of Sciences, Department of Chemistry, TR-58140, Sivas, Turkey.
    In the present study, a new preconcentration method was developed to quantify the free formaldehyde (FA) in hair cosmetics by combining ultrasound-assisted cloud-point extraction with spectrophotometry. The method is based on the ion association of FA with cationic phenothiazine group dye, toluidine blue in presence of sulfite at pH 5.0, and then extraction of the formed complex into the micellar phase of nonionic surfactant, Triton X-114. Read More

    Evisceration with autogenous scleral graft and bioceramic implantation within the modified scleral shell: 133 cases over 17 years.
    Orbit 2018 Apr 19:1-5. Epub 2018 Apr 19.
    b Department of Ophthalmology , Gui De Chauliac Hospital , Montpellier , France.
    Introduction: To present long-term follow-up data on evisceration performed with autogenous scleral grafting and ceramic implantation in a modified scleral shell.

    Methods: This was a retrospective analysis of all consecutive eviscerations performed in the Department of Ophthalmology, Montpellier University Hospital, France, between February 1998 and October 2015. For all patients, the technique used was a conventional anterior evisceration after total keratectomy, disinsertion of the medial rectus muscle, sectioning of the optic nerve and excision of sclera centered on the papilla. Read More

    Clinical utility of marketing terms used for over-the-counter dermatologic products.
    J Dermatolog Treat 2018 Apr 19:1-20. Epub 2018 Apr 19.
    a Department of Dermatology , Johns Hopkins University School of Medicine , Baltimore , MD , USA.
    Background: Cosmetic products are commonly marketed using dermatologic terms such as "hypoallergenic," "non-comedogenic," "fragrance-free," etc. The clinical relevance of these claims can be confusing to both patients and clinicians.

    Methods: A systematic review was performed from via a PubMed search of published articles from January 1985 to October 2017 to further describe and elucidate the clinical utility of a predefined list of common dermatologic terms used by pharmaceutical companies to market over the counter products. Read More

    Dye Removal from Water and Wastewater Using Various Physical, Chemical, and Biological Processes.
    J AOAC Int 2018 Apr 18. Epub 2018 Apr 18.
    Koszalin University of Technology, Faculty of Civil Engineering, Department of Environmental Technologies and Bioanalytics, Environmental and Geodetic Sciences, Sniadeckich 2, Koszalin, Poland 75-453.
    Synthetic dyes or colorants are key chemicals for various industries producing textiles, food, cosmetics, pharmaceutics, printer inks, leather, and plastics. Nowadays, the textile industry is the major consumer of dyes. The mass of synthetic colorants used by this industry is estimated at the level of 1 ÷ 3 × 10 tons, in comparison with the total annual consumption of around 7 × 10 tons worldwide. Read More

    Mass Spectrometric Analysis of Synthetic Organic Pigments.
    J AOAC Int 2018 Apr 18. Epub 2018 Apr 18.
    National Institute of Health Sciences, Division of Environmental Chemistry, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki 210-9501, Japan.
    Though synthetic organic colorants are used in various applications nowadays, there is the concern that impurities by-produced during the manufacturing and degradation products in some of these colorants are persistent organic pollutants and carcinogens. Thus, it is important to identify the synthetic organic colorants in various products, such as commercial paints, ink, cosmetics, food, textile, and plastics. Dyes, which are soluble in water and other solvents, could be analyzed by chromatographic methods. Read More

    Band Alignment-Driven Oxidative Injury to the Skin by Anatase/Rutile Mixed-Phase Titanium Dioxide Nanoparticles under Sunlight Exposure.
    Toxicol Sci 2018 Apr 12. Epub 2018 Apr 12.
    Laboratory of Chemical Biology, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, (P. R. China).
    Anatase/rutile mixed-phase titanium dioxide (TiO2) nanoparticles (NPs) have been found in cosmetics and cotton textiles. Once exposed to sunlight, mixed-phase TiO2 NPs are even more toxic to cells than pure phase NPs, however, the underlying mechanism remains unclear. Considering the unique anatase/rutile heterojunction structure existing in mixed-phase NPs, the potent toxicity of mixed-phase TiO2 NPs probably originates from the high reactive oxygen species (ROS) production because the anatase/rutile heterojunction is constituted by the staggered energy bands that facilitate the electron-hole separation at the interface due to the band alignment. Read More

    Socioeconomic factors influencing cosmetic usage patterns.
    J Expo Sci Environ Epidemiol 2018 May;28(3):242-250
    Department of Dermatology, Dankook University Medical Center, Chungnam, Korea.
    Despite daily exposure to chemicals in cosmetic products, there are few studies on the exposure levels to cosmetics particularly in Asians. We sought to investigate the usage pattern of cosmetics, including eye makeup products, fragrances, color makeups, and hair and nail care products, in Koreans. An online survey of 1,800 participants (908 males and 892 females, aged 15-59 years) from 5 Metropolitan cities (Seoul, Incheon, Daejeon, Daegu, and Busan) in Korea was conducted. Read More

    FDA 2014 Survey of Eye Area Cosmetics for Microbiological Safety.
    Lett Appl Microbiol 2018 Apr 17. Epub 2018 Apr 17.
    Office of Cosmetics and Colors, Center for Food Safety and Applied Nutrition, Food and Drug Administration., 5001 Campus Drive, College Park, MD, 20740.
    In an attempt to assess cosmetics containing "nontraditional" preservatives, ninety-three eye area cosmetic products were selected based on labeled or marketed claims that these products were "green", "natural", "paraben-free", "preservative-free", or contained nontraditional preservatives (e.g., botanical extracts). Read More

    Photooxidation of Octahydro Tetramethyl Naphthalenylethanone (OTNE) in Perfumes and Aftershaves.
    Photochem Photobiol 2018 Apr 16. Epub 2018 Apr 16.
    Institute of Food Chemistry, University of Hohenheim, D-70599, Stuttgart, Germany.
    For consumer safety reasons, cosmetics that are exposed to light are evaluated with respect to phototoxicity and/or photoallergy (photosensitization). For perfumes/aftershaves, however, these tests are not performed with the cosmetic product but only with single fragrance compounds, which may influence the outcome. In the presence of a sensitizer, photoinduced oxidation of unsaturated fragrances might result in the formation of unwanted products. Read More

    Customized Peptide Biomaterial Synthesis via an Environment-Reliant Auto-Programmer Stigmergic Approach.
    Materials (Basel) 2018 Apr 16;11(4). Epub 2018 Apr 16.
    Wits Advanced Drug Delivery Platform Research Unit, Department of Pharmacy and Pharmacology, School of Therapeutic Sciences, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, 7 York Road, Parktown 2193, South Africa.
    Stigmergy, a form of self-organization, was employed here to engineer a self-organizing peptide capable of forming a nano- or micro-structure and that can potentially be used in various drug delivery and biomedical applications. These self-assembling peptides exhibit several desirable qualities for drug delivery, tissue engineering, cosmetics, antibiotics, food science, and biomedical surface engineering. In this study, peptide biomaterial synthesis was carried out using an environment-reliant auto-programmer stigmergic approach. Read More

    The Rheological and Skin Sensory Properties of Cosmetic Emulsions: Influence of Thickening Agents.
    J Cosmet Sci 2018 Jan/Feb;69(1):67-75
    ASI Shanghai Technical Centre, Ashland Inc., Shanghai 200233, China (Y.L., X.Z., X.Q.) and School of Science, Beijing Technology and Business University, Beijing 100048, China (Z.Z., H.Z.).
    Hydrophilic polymers are widely used in the cosmetics industry as thickening agents/rheology modifiers. These thickening agents have different chemical structures which affect the rheological properties, as well as the sensory attributes of the formula. Systematic study is important to determine the relationship among them. Read More

    Comparing the Influence of Five Patch Types on the Result of a 12-Day Cumulative Irritancy Patch Test.
    J Cosmet Sci 2018 Jan/Feb;69(1):57-66
    Department of Dermatology, West China Hospital, Sichuan University, Chengdu, China (X.W., L.L.) and Cosmetics Evaluation Center, West China Hospital, Sichuan University, Chengdu, China (X.S., L.Z., Z.L.).
    A 12-day cumulative irritancy patch test is available for predicting skin irritation potential. This study is important to determine the ideal patch type to be used in the irritancy patch test. This study was conducted to determine the cumulative skin irritation potential of five different patch types using predictive patch test techniques. Read More

    Optimization of spray drying conditions to microencapsulate cupuassu (Theobroma grandiflorum) seed by-product extract.
    Nat Prod Res 2018 Apr 16:1-9. Epub 2018 Apr 16.
    c Department of Civil, Chemical and Environmental Engineering , University of Genoa , Genoa , Italy.
    Cupuassu (Theobroma grandiflorum Schum.) is a popular Amazonian fruit because of its intense aroma and nutritional value, whose lipid fraction is alternatively used in cosmetics. To preserve active principles and ensure their controlled release, extract was microencapsulated by spray drying. Read More

    Trade-offs in ecosystem impacts from nanomaterial versus organic chemical ultraviolet filters in sunscreens.
    Water Res 2018 Mar 27;139:281-290. Epub 2018 Mar 27.
    School of Sustainable Engineering and the Built Environment, Nanosystems Engineering Research Center for Nanotechnology-Enabled Water Treatment, Arizona State University, Tempe, AZ 85287-3005, United States.
    Both nanoparticulate (nZnO and nTiO) and organic chemical ultraviolet (UV) filters are active ingredients in sunscreen and protect against skin cancer, but limited research exists on the environmental effects of sunscreen release into aquatic systems. To examine the trade-offs of incorporating nanoparticles (NPs) into sunscreens over the past two decades, we targeted endpoints sensitive to the potential risks of different UV filters: solar reactive oxygen production in water and disruption of zebrafish embryo development. First, we developed methodology to extract nanoparticles from sunscreens with organic solvents. Read More

    Photoallergic Contact Dermatitis to Sunscreens Containing Oxybenzone in La Plata, Argentina.
    Actas Dermosifiliogr 2018 Apr 11. Epub 2018 Apr 11.
    Chemotechnique Diagnostics, Vellinge, Suecia.
    Background: Photoallergic contact dermatitis (PACD) to oxybenzone was reported for the first time in 1980. Oxybenzone is the most common photoallergen in the United States and Canada and the fourth most common .in Europe. Read More

    Antimicrobial Ingredients as Preservative Booster and Components of Self-Preserving Cosmetic Products.
    Curr Microbiol 2018 Apr 12. Epub 2018 Apr 12.
    Faculty of Cosmetology, The Academy of Cosmetics and Health Care, Podwale 13 Street, 00-252, Warsaw, Poland.
    This review reports cosmetic ingredients with antimicrobial activity including synthetic and natural (plant and microbial) origin as alternative for preservatives used in cosmetics as well described mechanism of their action. Read More

    Aggregate exposure to common fragrance compounds: Comparison of the contribution of essential oils and cosmetics using probabilistic methods and the example of limonene.
    Food Chem Toxicol 2018 Apr 9;116(Pt B):77-85. Epub 2018 Apr 9.
    Laboratoire des Interactions Epithéliums Neurones, Université Bretagne Loire (UBL), UFR Sciences et Techniques, 6 Av. Victor Le Gorgeu, CS93837, 29238, Brest Cedex 3, France.
    The knowledge of aggregate exposure to different types of products is paramount in the risk assessment. The aim of this study was to compare the relative contribution of essential oils compared to cosmetics on the daily dermal exposure to limonene, an ubiquitous fragrance compound that can be an allergen depending on its degree of oxidation. Aggregate daily exposure to limonene was calculated among a panel of French volunteers using both essential oils and cosmetics, for 4 different specific zones, i. Read More

    Lipase catalyzed epoxidation of fatty acid methyl esters derived from unsaturated vegetable oils in absence of carboxylic acid.
    Chem Cent J 2018 Apr 11;12(1):39. Epub 2018 Apr 11.
    Facultad de Ciencias Químicas, Universidad Autónoma de Chihuahua, Nuevo Circuito Universitario, 31125, Chihuahua, Mexico.
    Nowadays the industrial chemistry reactions rely on green technologies. Enzymes as lipases are increasing its use in diverse chemical processes. Epoxidized fatty acid methyl esters obtained from transesterification of vegetable oils have recently found applications as polymer plasticizer, agrochemical, cosmetics, pharmaceuticals and food additives. Read More

    The Antioxidant Activity and Inhibition of Intracellular Reactive Oxygen Species of Sweet Potato Leaf Polyphenols.
    Oxid Med Cell Longev 2018 15;2018:9017828. Epub 2018 Feb 15.
    Key Laboratory of Agro-products Processing, Ministry of Agriculture, Laboratory of Food Chemistry and Nutrition Science, Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, 2 Yuan Ming Yuan West Road, Haidian District, Beijing 100193, China.
    The antioxidant activity and inhibition of intracellular reactive oxygen species (ROS) of the total and individual phenolic compounds from Yuzi No. 7 sweet potato leaves were investigated in this study. Sweet potato leaf polyphenols possessed significantly higher antioxidant activity than ascorbic acid, tea polyphenols, and grape seed polyphenols. Read More

    Structural Requirements of Alkylglyceryl-l-Ascorbic Acid Derivatives for Melanogenesis Inhibitory Activity.
    Int J Mol Sci 2018 Apr 10;19(4). Epub 2018 Apr 10.
    Pharmaceutical Research and Technology Institute, Kindai University, 3-4-1 Kowakae, Higashi-osaka, Osaka 577-8502, Japan.
    l-Ascorbic acid has multifunctional benefits on skin aesthetics, including inhibition of melanin production, and is widely used in cosmetics. It, however, has low stability and poor skin penetration. We hypothesize that alkylglyceryl-l-ascorbic acid derivatives, highly stable vitamin C-alkylglycerol conjugates, would have similar anti-melanogenic activity with better stability and penetration. Read More

    Fucoxanthin and Polyunsaturated Fatty Acids Co-Extraction by a Green Process.
    Molecules 2018 Apr 11;23(4). Epub 2018 Apr 11.
    Montpellier SupAgro, UMR 1208 IATE, 2 Place Viala, 34060 Montpellier CEDEX 2, France.
    By their autotrophic nature and their molecular richness, microalgae are serious assets in the context of current environmental and societal challenges. Some species produce both omega-3 long chain polyunsaturated fatty acids (PUFAs) and xanthophylls, two molecular families widely studied for their bioactivities in the fields of nutrition and cosmetics. Whereas most studies separately deal with the two families, synergies could be exploited with extracts containing both PUFAs and xanthophylls. Read More

    How Diverse Are the Protein-Bound Conformations of Small-Molecule Drugs and Cofactors?
    Front Chem 2018 27;6:68. Epub 2018 Mar 27.
    Department of Informatics, Center for Bioinformatics, Universität Hamburg, Hamburg, Germany.
    Knowledge of the bioactive conformations of small molecules or the ability to predict them with theoretical methods is of key importance to the design of bioactive compounds such as drugs, agrochemicals, and cosmetics. Using an elaborate cheminformatics pipeline, which also evaluates the support of individual atom coordinates by the measured electron density, we compiled a complete set ("Sperrylite Dataset") of high-quality structures of protein-bound ligand conformations from the PDB. The Sperrylite Dataset consists of a total of 10,936 high-quality structures of 4,548 unique ligands. Read More

    2-Thiophene ethylamine modified hyaluronic acid with its application on hepatocytes culture.
    Mater Sci Eng C Mater Biol Appl 2018 Jul 20;88:157-165. Epub 2018 Mar 20.
    School of Physical Science and Technology, ShanghaiTech University, 393 Middle Huaxia Road, Pudong, Shanghai 201210, China. Electronic address:
    Hyaluronic acid (HA) is a component of extracellular matrix, which is important for cell functions and tissue integrity. Biosynthesized HA, as well as its derivatives, is widely used in cosmetics industry, biochemical medicine and medical surgery. In this research, we report a new hyaluronic acid derivative synthesized by amidation of hyaluronic acid with 2-thiophene ethylamine (2TEA). Read More

    Helix aspersa maxima mucus exhibits antimelanogenic and antitumoral effects against melanoma cells.
    Biomed Pharmacother 2018 May 22;101:871-880. Epub 2018 Mar 22.
    Université de Tunis El Manar, Institut Pasteur de Tunis, Laboratoire des Venins et biomolécules thérapeutiques LR11IPT08/ LR16IPT08, Tunis, 1002, Tunisia. Electronic address:
    Snail secretion is currently revolutionizing the world of cosmetics and human skin care. The efficacy of snail secretion in wounds healing has been proven both in vitro and by clinical studies. However, the potential anti-tumor effect of snail secretion was poorly investigated. Read More

    Pharmacological and biotechnological advances with Rosmarinus officinalis L.
    Expert Opin Ther Pat 2018 May 10;28(5):399-413. Epub 2018 Apr 10.
    a Postgraduate Program in Biotechnology - RENORBIO , Focal Point - Federal University of Piauí , Teresina , Brazil.
    Introduction: Rosmarinus officinalis L. is an aromatic plant with a number of biological properties. Recently, has been studied regarding its therapeutic potential. Read More

    The Aesthetics of the Upper Face and Brow: Male and Female Differences.
    Facial Plast Surg 2018 Apr 9;34(2):114-118. Epub 2018 Apr 9.
    Private Practice, Sedgh Plastic Surgery, Los Angeles, California.
    A hallmark of the modern era of facial plastic surgery is the increasing demand for upper facial rejuvenation by both genders and the growing variety of such options, including both surgical and non-surgical modalities. Thus, now more than ever, differentiating these aesthetic ideals between the two genders and understanding their nuances has become a necessity for the facial cosmetics community. In this article, a detailed comparison of the the pertinent anatomical and topographical differences is presented, followed by a review of the historical evolution of these aesthetic trends. Read More

    Boosting Effect of Amphiphilic Random Copolymers for Bicontinuous Phases.
    J Oleo Sci 2018 Apr 9. Epub 2018 Apr 9.
    Department of Industrial Chemistry, Faculty of Engineering, Tokyo University of Science.
    Amphiphilic random copolymers, poly(oxyethylene)/poly(oxypropylene) butyl ethers (C4EmPn), have been used as raw materials for cosmetics. This paper reports on the influence of amphiphilic random copolymers on mixtures of n-decane, water, and a nonionic surfactant, hexa(oxyethylene) dodecyl ether (C12E6). Bicontinuous phases are formed from decane/water/C12E6 mixtures at high C12E6 weight fractions (> 70 wt%). Read More

    The synthesis of a new unsaturated derivative of chondroitin sulfate with increased antioxidant properties.
    Carbohydr Polym 2018 Jun 27;190:175-183. Epub 2018 Feb 27.
    Contipro a.s., Dolní Dobrouč 401, 56102, Czech Republic.
    Chondroitin sulfate (CS) was regio-specifically modified to an unsaturated derivative (ΔCS) with a double bond in positions 4 and 5 of N-acetyl-d-galactosamine. The structure of ΔCS was elucidated in detail by two dimensional nuclear magnetic resonance, ultraviolet spectroscopy and mass spectrometry. The introduction of a nucleophilic CC double bond into a polymer backbone had no influence on biocompatibility of CS, which was demonstrated by MTT live-dead assay and enzymatic degradation in vitro. Read More

    Photocatalytic degradation of aqueous Methyl Orange using nitrogen-doped TiO photocatalyst prepared by novel method of ultraviolet-assisted thermal synthesis.
    J Environ Sci (China) 2018 Apr 27;66:81-93. Epub 2017 May 27.
    Department of Chemical Engineering, Ryerson University, Toronto, ON M5B 2K3, Canada. Electronic address:
    A nitrogen-doped titanium dioxide composite photocatalyst (N-TiO) with heterojunction structures is synthesized by three different approaches: a novel UV-assisted thermal synthesis, annealing, and microwave technique. Photocatalytic activities of synthesized photocatalysts are evaluated by the degradation of Methyl Orange under ultraviolet light types A (UV-A), B (UV-B), and C (UV-C), visible light, and direct sunlight irradiation. Results show that by using N-TiO photocatalyst prepared by the UV-assisted thermal synthesis and annealing, the degradation increases by 16. Read More

    Photocatalytic properties of P25-doped TiO composite film synthesized via sol-gel method on cement substrate.
    J Environ Sci (China) 2018 Apr 29;66:71-80. Epub 2017 May 29.
    Key Laboratory of Integrated Regulation and Resource Development on Shallow Lakes, Ministry of Education, College of Environment, Hohai University, Nanjing 210098, China.
    TiO films have received increasing attention for the removal of organic pollutants via photocatalysis. To develop a simple and effective method for improving the photodegradation efficiency of pollutants in surface water, we herein examined the preparation of a P25-TiO composite film on a cement substrate via a sol-gel method. In this case, Rhodamine B (RhB) was employed as the target organic pollutant. Read More

    Effect of TiO nanoparticle aggregation on marine microalgae Isochrysis galbana.
    J Environ Sci (China) 2018 Apr 25;66:208-215. Epub 2017 May 25.
    The Second Institute of Oceanography, State Oceanic Administration, Laboratory of Ecosystem and Biogeochemistry, State Oceanic Administration, Hangzhou 310012, China.
    TiO nanoparticles (NPs) could adversely impact aquatic ecosystems. However, the aggregation of these NPs could attenuate this effect. In this work, the biological effects of TiO NPs on a marine microalgae Isochrysis galbana were investigated. Read More

    IN VIVO STUDIES AND STABILITY STUDY OF CLADOPHORA GLOMERATA EXTRACT AS A COSMETIC ACTIVE INGREDIENT.
    Acta Pol Pharm 2017 Mar;74(2):633-641
    Marine algae are widely used as cosmetics raw materials. Likewise, freshwater alga Cladophora glomerata may be a good source of fatty acids and others bioactive agents. The aims of this study was to find out if the addition of the extract from the freshwater C. Read More

    Therapeutic applications of bacterial pigments: a review of current status and future opportunities.
    3 Biotech 2018 Apr 4;8(4):207. Epub 2018 Apr 4.
    2UoN Chair of Oman's Medicinal Plants and Marine Natural Products, University of Nizwa, Nizwa-616, Sultanate of Oman, Nizwa-616, Birkat Al Mauz, P.O Box 33, 616 Nizwa, Oman.
    Non-toxicity, biodegradability and non-carcinogenicity of the natural pigments, dyes and colorants make them an attractive source for human use. Bacterial pigments are colored metabolites secreted by bacteria under stress. The industrial uses of bacterial pigments have increased many folds because of several advantages over the synthetic pigments. Read More

    Bromelain-loaded nanoparticles: A comprehensive review of the state of the art.
    Adv Colloid Interface Sci 2018 Mar 27. Epub 2018 Mar 27.
    Department of Pharmaceutical Technology of the Faculty of Pharmacy, University of Coimbra, Portugal; REQUIMTE - Group of Pharmaceutical Technology, Coimbra, Portugal.
    Stem bromelain is a common available cysteine protease derived from pineapple (Ananas comosus L.). Bromelain finds widespread applications in several areas, such as medicine, health, food, and cosmetics, and its strong proteolytic activity supports its future application in many additional fields. Read More

    Outpatient Talc Administration by Indwelling Pleural Catheter for Malignant Effusion.
    N Engl J Med 2018 04;378(14):1313-1322
    From the Academic Respiratory Unit, University of Bristol (R.B., S.P.W., A.C.B., N.A.M.), and North Bristol NHS Trust (R.B., E.K.K., A.J.M., S.P.W., A.C.B., S.S., L.J.S., N.J.Z.-E., J.E.H., N.A.M.), Bristol, the Pragmatic Clinical Trials Unit, Queen Mary University of London (B.C.K.), Guy's and St. Thomas' NHS Foundation Trust (L.A., A.W.), King's College School of Medicine, King's College University (L.A.), and the Institute for Global Health, University College London (R.F.M.), London, Great Western Hospitals NHS Foundation Trust, Swindon (A.E.S.), University Hospital of North Midlands NHS Trust, Stoke-on-Trent (M.H.), the School of Medicine, Keele University, Newcastle-under-Lyme (M.H.), North Tees and Hartlepool NHS Foundation Trust, Stockton-on-Tees (R.N.H.), South Tees Hospitals NHS Foundation Trust, Middlesbrough (R.A.M.), Portsmouth Hospitals NHS Trust, Portsmouth (L.J.B.), Manchester University NHS Foundation Trust, Manchester (J. Holme, M.E.), Lancashire Teaching Hospitals NHS Foundation Trust, Preston (M.M.), Cambridge University Hospitals NHS Foundation Trust, Cambridge (P.S., J. Herre), Northumbria Healthcare NHS Foundation Trust, North Shields (D.C.), Sherwood Forest Hospitals NHS Foundation Trust, Sutton-in-Ashfield (M.R.), NHS Ayrshire and Arran, Ayr (A.G.), Worcester Acute Hospitals NHS Trust, Worcester (C.H.), Royal United Hospitals Bath NHS Foundation Trust, Bath (J.W.), Blackpool Teaching Hospitals NHS Foundation Trust, Blackpool (T.S.S.), Aintree University Hospitals NHS Foundation Trust, Liverpool (B.C.), Hampshire Hospitals NHS Foundation Trust, Winchester (S.G.), and the Oxford Respiratory Trials Unit, University of Oxford (I.P., N.M.R.), the Oxford University Hospitals NHS Foundation Trust (I.P., N.M.R.), and the Oxford NIHR Biomedical Research Centre (N.M.R.), Oxford - all in the United Kingdom; and the Institute for Respiratory Health, University of Western Australia, and Sir Charles Gairdner Hospital, Perth, WA, Australia (Y.C.G.L.).
    Background: Malignant pleural effusion affects more than 750,000 persons each year across Europe and the United States. Pleurodesis with the administration of talc in hospitalized patients is the most common treatment, but indwelling pleural catheters placed for drainage offer an ambulatory alternative. We examined whether talc administered through an indwelling pleural catheter was more effective at inducing pleurodesis than the use of an indwelling pleural catheter alone. Read More

    Color profiles and stability of acylated and nonacylated anthocyanins as novel pigment sources in a lipstick model: A viable alternative to synthetic colorants.
    J Cosmet Sci 2017 May/Jun;68(3):233-244
    Department of Food Science and Technology, The Ohio State University, Columbus, OH.
    Cosmetics, such as lipstick, can affect an individual's perception of attractiveness and morale. Consumer concern with the safety of synthetic colorants has made the need for alternative natural color sources increasingly urgent. Our goal was to evaluate the feasibility of anthocyanin (ACN) extracts as colorants in lipstick formulations. Read More

    Assessment of bacterial contamination of lipstick using pyrosequencing.
    J Cosmet Sci 2017 Jul/Aug;68(4):245-252
    Department of Oral Microbiology, Research Institute of Oral Science, Gangneung-Wonju National University, Gangneung, 210-702, Korea.
    As soon as they are exposed to the environment, cosmetics become contaminated with microorganisms, and this contamination accumulates with increased use. In this study, we employed pyrosequencing to investigate the diversity of bacteria found on lipstick. Bacterial DNA was extracted from 20 lipstick samples and mixed in equal ratios for pyrosequencing analysis. Read More

    A Comparative In Vivo Scrutiny of Biosynthesized Copper and Zinc Oxide Nanoparticles by Intraperitoneal and Intravenous Administration Routes in Rats.
    Nanoscale Res Lett 2018 Apr 3;13(1):93. Epub 2018 Apr 3.
    Medical Biotechnology and Phage Therapy Laboratory, Department of Post Graduate Studies and Research in Biotechnology, Gulbarga University, Gulbarga, Karnataka, 585 106, India.
    During the present time, anti-microbial features of copper (Cu) and zinc oxide (ZnO) nanoparticles (NPs) are extensively used to combat the growth of pathogenic microbes. CuNPs and ZnONPs are recurrently used in cosmetics, medicine and food additives, and their potential for toxic impacts on human and ecosystem is of high concern. In this study, the fate and toxicity of 16- to 96-nm-ranged biosynthesized copper (Bio-CuNPs) and zinc oxide (Bio-ZnONPs) was assessed in male Wistar rats. Read More

    Extracellular polymer substance synthesized by a halophilic bacterium Chromohalobacter canadensis 28.
    Appl Microbiol Biotechnol 2018 Apr 3. Epub 2018 Apr 3.
    Institute of Microbiology, Bulgarian Academy of Sciences, Acad G. Bonchev Str. Bl. 26, 1113, Sofia, Bulgaria.
    Halophilic microorganisms are producers of a lot of new compounds whose properties suggest promising perspectives for their biotechnological exploration. Moderate halophilic bacterium Chromohalobacter canadensis 28 was isolated from Pomorie salterns as an extracellular polymer substance (EP) producer. The best carbon source for extracellular polymer production was found to be lactose, a sugar received as a by-product from the dairy industry. Read More

    A Review of the Medical Necessity of Comprehensive Patch Testing.
    Dermatitis 2018 Apr 2. Epub 2018 Apr 2.
    Allergic contact dermatitis is associated with significant disease and economic burden in the United States. To properly manage allergic contact dermatitis, it is important to accurately identify the substance(s) implicated in the dermatitis to prevent disease recurrence. The commercially available T. Read More

    One-Pot Regiospecific Synthesis of Indolizines: A Solvent-Free, Metal-Free, Three-Component Reaction of 2-(Pyridin-2-yl)acetates, Ynals, and Alcohols or Thiols.
    Org Lett 2018 Apr 3;20(8):2477-2480. Epub 2018 Apr 3.
    School of Chemistry and Chemical Engineering and Guangdong Cosmetics Engineering & Technology Research Center , Guangdong Pharmaceutical University , Zhongshan 528458 , China.
    A novel approach for the synthesis of indolizines from 2-(pyridin-2-yl)acetates, ynals, and alcohols or thiols has been developed. This MCR (multicomponent reaction) that proceeds under the solvent- and metal-free conditions has provided a straightforward path to construct indolizines. Furthermore, this reaction demonstrates other attractive features such as widely available starting materials, mild conditions, good functional group tolerance, and high efficiency. Read More

    Antibacterial potential of secondary metabolites produced by Aspergillus sp., an endophyte of Mitrephora wangii.
    Arch Microbiol 2018 Apr 2. Epub 2018 Apr 2.
    School of Science, Mae Fah Luang University, 333 moo 1 Thasud, Muang, Chiang Rai, 57100, Thailand.
    Mitrephora wangii, an ethnomedicinal plant, has been used as a natural antibiotic and immunity booster in Thailand. A total of 22 fungi were isolated from M. wangii flowers. Read More

    Formulation and Stabilization of Concentrated Edible Oil-in-Water Emulsions Based on Electrostatic Complexes of a Food-Grade Cationic Surfactant (Ethyl Lauroyl Arginate) and Cellulose Nanocrystals.
    Biomacromolecules 2018 Apr 11. Epub 2018 Apr 11.
    Bio-Based Colloids and Materials, Department of Bioproducts and Biosystems, School of Chemical Engineering , Aalto University , P.O. Box 16300, FIN-00076 Aalto , Espoo , Finland.
    We report on high-internal-phase, oil-in-water Pickering emulsions that are stable against coalescence during storage. Viscous, edible oil (sunflower) was emulsified by combining naturally derived cellulose nanocrystals (CNCs) and a food-grade, biobased cationic surfactant obtained from lauric acid and L-arginine (ethyl lauroyl arginate, LAE). The interactions between CNC and LAE were elucidated by isothermal titration calorimetry (ITC) and supplementary techniques. Read More

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