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    The Complete Chloroplast Genome Sequences of Aconitum pseudolaeve and Aconitum longecassidatum, and Development of Molecular Markers for Distinguishing Species in the Aconitum Subgenus Lycoctonum.
    Molecules 2017 Nov 21;22(11). Epub 2017 Nov 21.
    K-herb Research Center, Korea Institute of Oriental Medicine, Daejeon 305-811, Korea.
    Aconitum pseudolaeve Nakai and Aconitum longecassidatum Nakai, which belong to the Aconitum subgenus Lycoctonum, are distributed in East Asia and Korea. Aconitum species are used in herbal medicine and contain highly toxic components, including aconitine. A. Read More

    Germacrone and sesquiterpene-enriched extracts from Curcuma aeruginosa Roxb. increase skin penetration of minoxidil, a hair growth promoter.
    Drug Deliv Transl Res 2017 Nov 20. Epub 2017 Nov 20.
    Bioscreening Unit, Department of Pharmaceutical Chemistry and Pharmacognosy, Faculty of Pharmaceutical Sciences and Center of Excellence for Innovation in Chemistry, Naresuan University, Phitsanulok, 65000, Thailand.
    Minoxidil is approved for topical treatment of androgenic alopecia but hampered by poor cutaneous absorption. Recently, the randomized control trial showed that hair loss treatment of minoxidil was improved by co-application of the anti-androgen, Curcuma aeruginosa Roxb. extract. Read More

    Superhydrophobic diving flies (Ephydra hians) and the hypersaline waters of Mono Lake.
    Proc Natl Acad Sci U S A 2017 Nov 20. Epub 2017 Nov 20.
    Department of Biology, California Institute of Technology, Pasadena, CA 91125.
    The remarkable alkali fly, Ephydra hians, deliberately crawls into the alkaline waters of Mono Lake to feed and lay eggs. These diving flies are protected by an air bubble that forms around their superhydrophobic cuticle upon entering the lake. To study the physical mechanisms underlying this process we measured the work required for flies to enter and leave various aqueous solutions. Read More

    Eucalyptus globulus extract protects against UVB-induced photoaging by enhancing collagen synthesis via regulation of TGF-β/Smad signals and attenuation of AP-1.
    Arch Biochem Biophys 2017 Nov 14. Epub 2017 Nov 14.
    College of Life Sciences, Kyung Hee University, 1732, Deogyeong-daero, Giheung-gu, Yongin-si, Gyeonggi-do 17104, Republic of Korea. Electronic address:
    UV irradiation triggers the overproduction of matrix metalloproteinases and collagen degradation, which in turn causes increased pigmentation, dryness, and deep wrinkling of the skin. These chronic symptoms are collectively referred to as photoaging. Eucalyptus globulus is an evergreen tree that is widely used in cosmetics because of its antimicrobial activity. Read More

    Effect of nanoliposomes containing Zataria multiflora Boiss. essential oil on gene expression of Shiga-toxin 2 in Escherichia coli O157:H7.
    J Appl Microbiol 2017 Nov 20. Epub 2017 Nov 20.
    Department of Food Hygiene, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
    Aims: Enterohaemorrhagic Escherichia coli (EHEC) serotype O157:H7 as a major human pathogen is responsible for food borne outbreaks, bloody diarrhea, hemorrhagic colitis and hemolytic uremic syndrome (HUS) and even death. In this study, the antibacterial activity of the Zataria multiflora essential oil (ZMEO) and nanoliposome-encapsulated ZMEO was evaluated on the pathogenicity of Escherichia coli O157:H7.

    Methods And Results: The minimum inhibitory concentrations (MIC) of essential oil (EO) were determined against the bacterium before and after encapsulation into nanoliposome. Read More

    Silver nanoparticles stimulate the proliferation of sulfate reducing bacterium Desulfovibrio vulgaris.
    Water Res 2017 Nov 8;129:163-171. Epub 2017 Nov 8.
    Advanced Water Management Centre, The University of Queensland, St Lucia, Brisbane, QLD 4072, Australia. Electronic address:
    The intensive use of silver nanoparticles (AgNPs) in cosmetics and textiles causes their release into sewer networks of urban water systems. Although a few studies have investigated antimicrobial activities of nanoparticles against environmental bacteria, little is known about potential impacts of the released AgNPs on sulfate reducing bacteria in sewers. Here, we investigated the effect of AgNPs on Desulfovibrio vulgaris Hidenborough (D. Read More

    A review on moringa tree and vetiver grass - Potential biorefinery feedstocks.
    Bioresour Technol 2017 Oct 31. Epub 2017 Oct 31.
    Bioenergy and Energy Planning Research Group, EPFL, Switzerland. Electronic address:
    Plants and derivatives have been explored for unlimited purposes by mankind, from crop cultivation for providing food and animal feed, to the use for cosmetics, therapeutics and energy. Moringa tree and vetiver grass features, capabilities and applications were explored through a literature review. The suitability of these plants for the bioenergy industry products is evidenced, namely for bioethanol, biogas and biodiesel, given the lignocellulosic biomass content of these plants and characteristics of moringa seed oil. Read More

    Structural emergence in particle dispersions.
    Langmuir 2017 Nov 16. Epub 2017 Nov 16.
    Particle dispersions, such as pigment-based inks, comprise weakly bound, milled nanoparticles. The properties of these pigments depend on both their chemical composition, as well as a rather complex structural hierarchy, which emerges from these dispersions. The emergence of structure under semi-dilute conditions is related to the structure of the dilute particles, the particle spacing (mesh size), processing history, and the interaction potential. Read More

    Confocal Raman spectroscopic imaging for in vitro monitoring of active ingredient penetration and distribution in Reconstructed Human Epidermis model.
    J Biophotonics 2017 Nov 16. Epub 2017 Nov 16.
    Université François-Rabelais de Tours, Faculty of Pharmacy, EA6295 Nanomédicament et Nanosondes, 31 avenue Monge, 37200, Tours, France.
    Topically applied Active Cosmetic Ingredients (ACI) or Active Pharmaceutical Ingredients (API) efficacy is directly related to their efficiency of penetration in the skin. In vitro Reconstructed Human Epidermis (RHE) surrogate models offer in vivo like skin samples for transdermal studies. Using Delipidol®, an ACI currently used in the cosmetics industry, the capabilities to deliver accurate distribution maps and penetration profiles of this molecule by means of Confocal Raman spectroscopic Imaging have been demonstrated. Read More

    Collagen: A review on its sources and potential cosmetic applications.
    J Cosmet Dermatol 2017 Nov 16. Epub 2017 Nov 16.
    Dpto. de Ciencia y Tecnología, Laboratorio de Ingeniería Genética y Biología Celular y Molecular - Área Virosis Emergentes y Zoonóticas, Universidad Nacional Quilmes, Bernal, Argentina.
    Collagen is a fibrillar protein that conforms the conjunctive and connective tissues in the human body, essentially skin, joints, and bones. This molecule is one of the most abundant in many of the living organisms due to its connective role in biological structures. Due to its abundance, strength and its directly proportional relation with skin aging, collagen has gained great interest in the cosmetic industry. Read More

    Actual consumption amount of personal care products reflecting Japanese cosmetic habits.
    J Toxicol Sci 2017 ;42(6):797-814
    Safety Subcommittee, Japan Cosmetic Industry Association.
    Safety assessments of cosmetics are carried out by identifying possible harmful effects of substances in cosmetic products and assessing the exposure to products containing these substances. The present study provided data on the amounts of cosmetic products consumed in Japan to enhance and complement the existing data from Europe and the United States, i.e. Read More

    SLN- and NLC-encapsulating antifungal agents: skin drug delivery and their unexplored potential for treating onychomycosis.
    Curr Pharm Des 2017 Nov 14. Epub 2017 Nov 14.
    Laboratory of Nanosystems and Drug Delivery Devices (NanoSYS), School of Pharmacy, Universidade Federal de Goias, Rua 240, esq. com 5ª Avenida, Setor Leste Universitario, 74605-170, Goiania, GO. Brazil.
    Background: Lipid nanoparticles have been extensively studied for drug delivery of antifungal drugs, especially for dermatophytosis treatments. They can accumulate in skin appendages and release drugs in a controlled manner and also increase skin moisture, due to the formation of an occlusive film. Since moisture heavily influences nail and skin permeability, these systems seem to pose great potential for antifungal drug delivery. Read More

    Larix decidua Bark as a Source of Phytoconstituents: An LC-MS Study.
    Molecules 2017 Nov 15;22(11). Epub 2017 Nov 15.
    Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Via Marzolo 5, 35131 Padova, Italy.
    Larix decidua bark is a waste of the timber industry and is widely diffused in Northern Italy. This material can be considered a good source of antioxidants and phytoconstituents with possible use in cosmetic or nutraceutical products. In this study, simple extraction of larch bark was performed using mixtures of ethanol/water. Read More

    Characterization of biochemical traits of dog rose (Rosa canina L.) ecotypes in the central part of Iran.
    Nat Prod Res 2017 Nov 14:1-6. Epub 2017 Nov 14.
    c Young Researcher, Elite Club, Shahrekord Branch , Islamic Azad University , Shahrekord , Iran.
    Dog rose (Rosa canina L.) is a wild native species in Iran, with a significant genetic diversity. This plant serves as a rich source of vitamin C, anthocyanins, phenolic contents and carotenoids. Read More

    (1)H NMR assisted quantification of glycerol carbonate in the mixture of glycerol and glycerol carbonate.
    Talanta 2018 Feb 1;178:1001-1005. Epub 2017 Sep 1.
    School of Chemistry and Biochemistry, Thapar University, Patiala 147004, India. Electronic address:
    Glycerol carbonate (GLC) is a very important chemical having a variety of application viz., green solvent in organic synthesis, an electrolyte in lithium batteries, wetting agent in cosmetics and precursor in polymer and food industry for the synthesis of 1,3-sn-diglycerides. Hence, it is vital to find out the quick and simple method for the quantification of GLC when it is synthesized via dimethyl carbonate (DMC) assisted transesterification with glycerol (GL). Read More

    Medicinally important aromatic plants with radioprotective activity.
    Future Sci OA 2017 Nov 21;3(4):FSO247. Epub 2017 Sep 21.
    Tokyo Institute of Technology, Institute of Innovative Research, Laboratory for Advanced Nuclear Energy, N1-30 2-12-1 Ookayama, Meguro-ku, Tokyo 152-8550, Japan.
    Aromatic plants are often used as natural medicines because of their remedial and inherent pharmacological properties. Looking into natural resources, particularly products of plant origin, has become an exciting area of research in drug discovery and development. Aromatic plants are mainly exploited for essential oil extraction for applications in industries, for example, in cosmetics, flavoring and fragrance, spices, pesticides, repellents and herbal beverages. Read More

    Plant stem cells in cosmetics: current trends and future directions.
    Future Sci OA 2017 Nov 12;3(4):FSO226. Epub 2017 Jul 12.
    Center for Dermal Research, Center for Biomaterials, Rutgers - The State University of New Jersey, Piscataway, NJ 08854, USA.
    Plant regeneration at the cellular and tissue level is a unique process. Similar to animals, the stem cells in plants have properties that help stimulate and regenerate plants after injury. The unique properties of plant stem cells have been a recent area of interest and focus both in developing new cosmetics and studying how these extracts/phytohormones will influence animal skin. Read More

    Surfactants and their role in wound cleansing and biofilm management.
    J Wound Care 2017 Nov;26(11):680-690
    Professor, Institute for Wound Research, Department Obstetrics and Gynaecology, University of Florida, Gainesville, US.
    Surfactants are widely used as detergents, emulsifiers, wetting agents, foaming agents and dispersants in the cosmetics, hygiene, food and oil industries. Their use in a clinical setting is also common, particularly within the field of wound care. Many wound cleansers contain surfactants and subsequently there is available data that shows the growing potential of these wound cleansers in the enhancement of wound closure. Read More

    Microplastic potentiates triclosan toxicity to the marine copepod Acartia tonsa (Dana).
    J Toxicol Environ Health A 2017 Nov 13:1-3. Epub 2017 Nov 13.
    a Department of Science and Environment , Roskilde University , Roskilde , Denmark.
    Microplastics (MP) are contaminants of environmental concern partly due to plastics ability to sorb and transport hydrophobic organic contaminants (HOC). The importance of this "vector effect" is currently being debated in the scientific community. This debate largely ignores that the co-exposures of MP and HOC are mixtures of hazardous agents, which can be addressed from a mixture toxicity perspective. Read More

    Formulation and Composition Effects in Phase Transitions of Emulsions Costabilized by Cellulose Nanofibrils and an Ionic Surfactant.
    Biomacromolecules 2017 Nov 21. Epub 2017 Nov 21.
    Graduate School of Bioresource and Bioenvironmental Sciences, Kyushu University , 6-10-1, Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan.
    Cellulose nanofibrils (CNF) offer great prospects as a natural stabilizer of colloidal dispersions and complex fluids for application in food, pharma, and cosmetics. In this study, an ionic surfactant (sodium dodecyl sulfate, SDS) was used as emulsifier of oil-in-water and water-in-oil emulsions that were further costabilized by addition of CNF. The adsorption properties of SDS in both, CNF dispersions and emulsions, as well as the influence of composition (CNF and SDS concentration) and formulation (ionic strength, oil, and CNF types) on the phase behavior were elucidated and described in the framework of Windsor systems. Read More

    Developmental Toxicity Assay for Food Additive Tartrazine Using Zebrafish ( Danio rerio) Embryo Cultures.
    Int J Toxicol 2017 Jan 1:1091581817735227. Epub 2017 Jan 1.
    1 Department of Zoology, Karnatak University, Dharwad, Karnataka, India.
    Tartrazine (TTZ) is an azo dye used as a colorant in food products, drugs, and cosmetics. The present study evaluates the impacts of TTZ on embryonic development of zebrafish ( Danio rerio). Laboratory-raised D. Read More

    Nicotine delivery efficiency of first- and second-generation e-cigarettes and its impact on relief of craving during the acute phase of use.
    Int J Hyg Environ Health 2017 Oct 28. Epub 2017 Oct 28.
    Bavarian Health and Food Safety Authority, Department of Chemical Safety and Toxicology, Pfarrstrasse 3, 80538 Munich, Germany. Electronic address:
    Knowledge about the change in blood nicotine concentrations during the first five minutes (acute phase) of e-cigarette vaping is important to determine whether the used product has a dependence potential or may be an efficient nicotine replacement product. To address this issue, we monitored blood nicotine levels during the acute phase in volunteers using disposable cigalikes (CLs) and a tank model (TM) and compared them with blood nicotine levels in subjects using a tobacco cigarette (TC). In parallel, heart rate changes were continually measured and withdrawal symptoms and craving were assessed with the Questionnaire on Smoking Urges before and immediately after the vaping/smoking sessions. Read More

    A validated UPLC-MS/MS method for biomonitoring the exposure to the fragrance 7-hydroxycitronellal.
    J Chromatogr B Analyt Technol Biomed Life Sci 2017 Nov 26;1068-1069:261-267. Epub 2017 Oct 26.
    Analytisch-Biologisches Forschungslabor GmbH, Semmelweisstr. 5, 82152 Planegg, Germany. Electronic address:
    7-Hydroxycitronellal is a synthetic fragrance (CAS No. 107-75-5) which is used commonly in cosmetics, washing- and cleaning agents and as flavoring in foods. Due to its broad application in various fields, 7-hydroxycitronellal was selected for the development of a biomonitoring method for the quantitative exposure assessment within the frame of the cooperation project of the German Federal Ministry for the Environment, Nature Conservation, Building and Nuclear Safety (BMUB) and the German Chemical Industry Association (VCI). Read More

    Miniaturized matrix solid-phase dispersion followed by liquid chromatography-tandem mass spectrometry for the quantification of synthetic dyes in cosmetics and foodstuffs used or consumed by children.
    J Chromatogr A 2017 Dec 27;1529:29-38. Epub 2017 Oct 27.
    Laboratory of Research and Development of Analytical Solutions (LIDSA), Department of Analytical Chemistry, Nutrition and Food Science, Faculty of Chemistry, Universidade de Santiago de Compostela, E-15782, Santiago de Compostela, Spain. Electronic address:
    Miniaturized matrix solid-phase dispersion (MSPD) followed by liquid chromatography tandem mass spectrometry (LC-MS/MS) has been proposed for the simultaneous analysis of different classes of synthetic dyes in confectionery and cosmetics intended for or mostly consumed by children. Selected compounds include most of the permitted dyes as food additives as well as some of the most frequently used to color cosmetic products in accordance with the respective European directives. MSPD procedure was optimized by means of experimental design, allowing an effective, rapid and simple extraction of dyes with low sample and reagents consumption (0. Read More

    Ectoine protects DNA from damage by ionizing radiation.
    Sci Rep 2017 Nov 10;7(1):15272. Epub 2017 Nov 10.
    Federal Institute for Materials Research and Testing, D-12205, Berlin, Germany.
    Ectoine plays an important role in protecting biomolecules and entire cells against environmental stressors such as salinity, freezing, drying and high temperatures. Recent studies revealed that ectoine also provides effective protection for human skin cells from damage caused by UV-A radiation. These protective properties make ectoine a valuable compound and it is applied as an active ingredient in numerous pharmaceutical devices and cosmetics. Read More

    What is an endocrine disruptor?
    C R Biol 2017 Sep - Oct;340(9-10):403-405
    Laboratoire de pharmacochimie, UMR 176, CNRS, Institut Curie (IC), Section Recherche, 26, rue d'Ulm, 75248 Paris cedex 05, France. Electronic address:
    Endocrine disrupting chemicals (EDCs) and potential EDCs are mostly man-made found in various materials. By interfering with the body's endocrine system, endocrine disruptors produce adverse developmental, reproductive, neurological, and immune effects in humans, abnormal growth patterns and neurodevelopmental delays in children. Thus, diethylstilbestrol (DES) a non-steroidal estrogen, which is regarded as a proof of concept, induces clear cell carcinoma among young women. Read More

    Comparative toxicological evaluation of nonylphenol and nonylphenol polyethoxylates using human keratinocytes.
    Drug Chem Toxicol 2017 Nov 10:1-6. Epub 2017 Nov 10.
    a Department of Life Science , Hanyang University , Seoul , Korea.
    Nonylphenol polyethoxylates (NPEOs) are a major group of nonionic surfactants widely used in various detergents, cleaners, plastics, papers, and agro-chemical products. Nonylphenol (NP), which is a final degraded metabolite derived from NPEOs, has been reported as an endocrine disrupter, known to mimic or disturb reproductive hormone functions. Concern about the hazards of NP and NPEOs has generated legal restrictions and action plans worldwide. Read More

    Broad screening of illicit ingredients in cosmetics using ultra-high-performance liquid chromatography-hybrid quadrupole-Orbitrap mass spectrometry with customized accurate-mass database and mass spectral library.
    J Chromatogr A 2017 Dec 6;1528:61-74. Epub 2017 Nov 6.
    Chinese Academy of Inspection and Quarantine, Beijing 100176, China. Electronic address:
    Comprehensive identification and quantitation of 100 multi-class regulated ingredients in cosmetics was achieved using ultra-high-performance liquid chromatography (UHPLC) coupled with hybrid quadrupole-Orbitrap high-resolution mass spectrometry (Q-Orbitrap HRMS). A simple, efficient, and inexpensive sample pretreatment protocol was developed using ultrasound-assisted extraction (UAE), followed by dispersive solid-phase extraction (dSPE). The cosmetic samples were analyzed by UHPLC-Q-Orbitrap HRMS under synchronous full-scan MS and data-dependent MS/MS (full-scan MS(1)/dd-MS(2)) acquisition mode. Read More

    Influence of hydrocarbon oil structure on adjuvanticity and autoimmunity.
    Sci Rep 2017 Nov 8;7(1):14998. Epub 2017 Nov 8.
    Division of Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, SE-171 77, Stockholm, Sweden.
    Mineral oils are extensively used in our daily life, in food, cosmetics, biomedicine, vaccines and in different industrial applications. However, exposure to these mineral oils has been associated with immune adjuvant effects and the development of autoimmune diseases. Here we investigate the structural impacts of the hydrocarbon oil molecules on their adjuvanticity and autoimmunity. Read More

    Metallic Nano-Composite Toxicity Evaluation by Zebrafish Embryo Toxicity Test with Identification of Specific Exposure Biomarkers.
    Curr Protoc Toxicol 2017 Nov 8;74:1.14.1-1.14.13. Epub 2017 Nov 8.
    Department of Biological, Geological and Environmental Science, University of Catania, Catania, Italy.
    Nanomaterials (NM) have different shapes and can be composed of different materials such as carbon, silicon, and some metals like gold, silver, and titanium. They are used as fillers, catalysts, semiconductors, cosmetics, drug carriers in medicine, energy storage systems, and antifriction coatings. NM are the parent compounds of nanoparticles (NPs), which may be divided into two groups: fullerenes and engineered nanoparticles (ENPs). Read More

    Nanoscale considerations responsible for diverse macroscopic phase behavior in monosubstituted isobutyl-POSS/poly(ethylene oxide) blends.
    Soft Matter 2017 Nov 8. Epub 2017 Nov 8.
    Department of Textile Engineering, Chemistry & Science and Fiber & Polymer Science Program, North Carolina State University, Raleigh, NC 27695, USA.
    Nanocomposites prepared by incorporating functionalized polyhedral oligomeric silsesquioxane (POSS) into polymer matrices afford a wide range of versatile hybrid materials for use in technologies ranging from cosmetics and pharmaceuticals to sensors and batteries. Here, we investigate the phase behavior of nanocomposites composed of poly(ethylene oxide) (PEO) and monosubstituted isobutyl POSS (iPOSS) modified with different functional moieties. Microscopic analyses of blends containing these iPOSS variants reveal the existence of different macroscopic morphologies and surface topologies. Read More

    Nanoparticle-Cell Interactions: Relevance for Public Health.
    J Phys Chem B 2017 Nov 21. Epub 2017 Nov 21.
    School of Chemistry and Biochemistry, Georgia Institute of Technology , Atlanta, Georgia 30332, United States.
    Nanoparticles, especially metal oxide nanoparticles, are used in a wide range of commercial and industrial applications that result in direct human contact, such as titanium dioxide nanoparticles in paints, food colorings, and cosmetics, or indirectly through release of nanoparticle-containing materials into the environment. Workers who process nanoparticles for downstream applications are exposed to especially high concentrations of nanoparticles. For physical chemists, nanoparticles present an interesting area of study as the small size of nanoparticles changes the properties from that of the bulk material, leading to novel properties and reactivity. Read More

    Biogenic silver nanoparticles inducing Leishmania amazonensis promastigote and amastigote death in vitro.
    Acta Trop 2017 Oct 27;178:46-54. Epub 2017 Oct 27.
    Laboratory of Experimental Protozoology, Department of Pathological Sciences, Center of Biological Sciences, State University of Londrina, Londrina, Paraná, Brazil.
    American Cutaneous Leishmaniasis (ACL) is a zoonosis caused by Leishmania protozoa. The ACL chemotherapy available is unsatisfactory motivating researches to seek alternative treatments. In this study, we investigated the action of biogenic silver nanoparticle (AgNp-bio) obtained from Fusarium oxysporium, against Leishmania amazonensis promastigote and amastigote forms. Read More

    Drug release from porous matrixes based on natural polymers.
    Curr Pharm Biotechnol 2017 Nov 3. Epub 2017 Nov 3.
    Department of Chemistry of Biomaterials and Cosmetics, Faculty of Chemistry, Nicolaus Copernicus University in Torun. Poland.
    Background: This review provides a report on recent advances in the field of drug release from matrixes made of natural polymers. Such matrixes have attracted not only academic but also practical attention in the case of several biopolymers since these can be used for biomedical purposes due to their interesting properties. Herein, the properties of natural polymers such as proteins and polysaccharides are discussed in general. Read More

    The crop-residue of fiber hemp cv. Futura 75: from a waste product to a source of botanical insecticides.
    Environ Sci Pollut Res Int 2017 Nov 6. Epub 2017 Nov 6.
    School of Pharmacy, University of Camerino, Camerino, Italy.
    In the attempt to exploit the potential of the monoecious fiber hemp cv. Futura 75 in new fields besides textile, cosmetics and food industry, its crop-residue given by leaves and inflorescences was subjected to hydrodistillation to obtain the essential oils. These are niche products representing an ideal candidate for the development of natural insecticides for the control and management of mosquito vectors, houseflies and moth pests. Read More

    Physicochemical study of ascorbic acid 2-glucoside loaded hyaluronic acid dissolving microneedles irradiated by electron beam and gamma ray.
    Carbohydr Polym 2018 Jan 13;180:297-303. Epub 2017 Oct 13.
    Department of Biotechnology, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea; Juvic Inc., Yonsei Engineering Research Park, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea. Electronic address:
    A dissolving microneedle (DMN) patch encapsulated with ascorbic acid 2-glucoside (AA2G) in a needle-shaped hyaluronic acid (HA) backbone was fabricated and sterilized by electron beam (e-beam, 5-40kGy) and gamma ray (γ-ray, 5-30kGy). DMN structures maintained their morphologies and fracture force regardless of e-beam and γ-ray irradiation doses. Both e-beam (40kGy) and γ-ray (20 and 30kGy) met the product sterility requirements for cosmetics and vaccines; however, γ-ray irradiation significantly degraded the encapsulated AA2G, while e-beam maintained AA2G activity. Read More

    Application of xanthan gum as polysaccharide in tissue engineering: A review.
    Carbohydr Polym 2018 Jan 5;180:128-144. Epub 2017 Oct 5.
    School of Chemical Engineering, Yeungnam University, 280 Daehak-Ro, Gyeongsan 38541, South Korea; Department of Nano, Medical and Polymer Materials, Yeungnam University, 280 Daehak-Ro, Gyeongsan 38541, South Korea. Electronic address:
    Xanthan gum is a microbial high molecular weight exo-polysaccharide produced by Xanthomonas bacteria (a Gram-negative bacteria genus that exhibits several different species) and it has widely been used as an additive in various industrial and biomedical applications such as food and food packaging, cosmetics, water-based paints, toiletries, petroleum, oil-recovery, construction and building materials, and drug delivery. Recently, it has shown great potential in issue engineering applications and a variety of modification methods have been employed to modify xanthan gum as polysaccharide for this purpose. However, xanthan gum-based biomaterials need further modification for several targeted applications due to some disadvantages (e. Read More

    Characterization of phthalates exposure and risk for cosmetics and perfume sales clerks.
    Environ Pollut 2017 Nov 2;233:577-587. Epub 2017 Nov 2.
    Research Center of Environmental Trace Toxic Substances, National Cheng Kung University, Tainan, Taiwan; Department of Environmental and Occupational Health, National Cheng Kung University, College of Medicine, Tainan, Taiwan. Electronic address:
    High levels of phthalates in name-brand cosmetics products have raised concerns about phthalate exposure and the associated risk for cosmetics sales clerks. We assessed the exposure and risk of phthalates in 23 cosmetics, 4 perfume, and 9 clothing department store sales clerks. We collected 108 urine samples pre- and post-shift and analyzed for phthalate monoesters through liquid chromatography-electrospray ionization-tandem mass spectrometry. Read More

    Silica nanoparticles inhibit the cation channel TRPV4 in airway epithelial cells.
    Part Fibre Toxicol 2017 Nov 3;14(1):43. Epub 2017 Nov 3.
    Department of Cellular and Molecular Medicine, Laboratory of Ion Channel Research, KU Leuven; VIB Center for Brain & Disease Research, Leuven, Belgium.
    Background: Silica nanoparticles (SiNPs) have numerous beneficial properties and are extensively used in cosmetics and food industries as anti-caking, densifying and hydrophobic agents. However, the increasing exposure levels experienced by the general population and the ability of SiNPs to penetrate cells and tissues have raised concerns about possible toxic effects of this material. Although SiNPs are known to affect the function of the airway epithelium, the molecular targets of these particles remain largely unknown. Read More

    Oral administration of lyophilized Dunaliella salina, a carotenoid-rich marine alga, reduces tumor progression in mammary cancer induced rats.
    Food Funct 2017 Nov 2. Epub 2017 Nov 2.
    School of Bio-Sciences and Technology, VIT University, Vellore - 632 014, Tamil Nadu, India.
    Dunaliella salina is a photosynthetic cell factory used for the commercial production of food additives, cattle stock feed and cosmetics as well as active ingredients for pharmaceutical industries. The investigation of the in vivo antitumor activity of D. salina lyophilized powder (DSLP) against 7,12-dimethylbenz(a)anthracene (DMBA) induced mammary carcinogenesis in female Wistar rats indicated a dose-dependent effect of DSLP. Read More

    Observer-Blind Randomized Controlled Study of a Cosmetic Blend of Safflower, Olive and Other Plant Oils in the Improvement of Scar and Striae Appearance.
    Int J Cosmet Sci 2017 Nov 2. Epub 2017 Nov 2.
    proDERM Institute for Applied Dermatological Research, 22869, Schenefeld, Germany.
    Objective: The normal process of skin tissue repair following injury invariably results in visual scarring. It is known that topical treatment with hydrophobic cosmetics high in silicone and mineral oil content can improve the appearance of scars and striae. Given lifestyle preferences of many cosmetic consumers towards so-called natural treatments, the objective of this controlled randomized study was to investigate the efficacy of a plant body oil rich in oleic and linoleic acids (Bio Skin Oil(®) ) for improving the appearance of scars and striae. Read More

    A quantitative and non-contact technique to characterise microstructural variations of skin tissues during photo-damaging process based on Mueller matrix polarimetry.
    Sci Rep 2017 Oct 31;7(1):14702. Epub 2017 Oct 31.
    Shenzhen Key Laboratory for Minimal Invasive Medical Technologies, Institute of Optical Imaging and Sensing, Graduate School at Shenzhen, Tsinghua University, Shenzhen, 518055, China.
    Skin tissue consists of collagen and elastic fibres, which are highly susceptible to damage when exposed to ultraviolet radiation (UVR), leading to skin aging and cancer. However, a lack of non-invasive detection methods makes determining the degree of UVR damage to skin in real time difficult. As one of the fundamental features of light, polarization can be used to develop imaging techniques capable of providing structural information about tissues. Read More

    Our microbes not only produce antibiotics, they also overproduce amino acids.
    J Antibiot (Tokyo) 2017 Nov 1. Epub 2017 Nov 1.
    Charles A Dana Research Institute for Scientists Emeriti (R.I.S.E.), Drew University, Madison, NJ, USA.
    Fermentative production of amino acids is an important goal of modern biotechnology. Through fermentation, micro-organisms growing on inexpensive carbon and nitrogen sources can produce a wide array of valuable products including amino acids. The amino acid market is $8 billion and mainly impacts the food, pharmaceutical and cosmetics industries. Read More

    Purification, Characterization, and Antioxidant Activity of Polysaccharides Isolated from Cortex Periplocae.
    Molecules 2017 Oct 31;22(11). Epub 2017 Oct 31.
    College of Tobacco Science/National Tobacco Cultivation & Physiology & Biochemistry Research Center, Henan Agricultural University, Zhengzhou 450002, China.
    In this study, crude Cortex Periplocae polysaccharides (CCPPs) were extracted with water. CCPPs were decolored with AB-8 resin and deproteinated using papain-Sevage methods. Then, they were further purified and separated through DEAE-52 anion exchange chromatography and Sephadex G-100 gel filtration chromatography, respectively. Read More

    Stabilization of Collagen Fibrils by Gelatin Addition: A Study of Collagen/Gelatin Dense Phases.
    Langmuir 2017 Nov 31;33(45):12916-12925. Epub 2017 Oct 31.
    Sorbonne Universités, UPMC Université Paris 06, CNRS, Collège de France, LCMCP , F-75005 Paris, France.
    Collagen and its denatured form, gelatin, are biopolymers of fundamental interest in numerous fields ranging from living tissues to biomaterials, food, and cosmetics. This study aims at characterizing mixtures of those biopolymers at high concentrations (up to 100 mg·mL(-1)) at which collagen has mesogenic properties. We use a structural approach combining polarization-resolved multiphoton microscopy, polarized light microscopy, magnetic resonance imaging, and transmission electron microscopy to analyze gelatin and collagen/gelatin dense phases in their sol and gel states from the macroscopic to the microscopic scale. Read More

    Optimization of enzymatic esterification of dihydrocaffeic acid with hexanol in ionic liquid using response surface methodology.
    Chem Cent J 2017 May 26;11(1):44. Epub 2017 May 26.
    Laboratory of Natural Products, Institute of Bioscience, University Putra Malaysia, 43400, Serdang, Selangor, Malaysia.
    Background: Developing an efficient lipophilization reaction system for phenolic derivatives could enhance their applications in food processing. Low solubility of phenolic acids reduces the efficiency of phenolic derivatives in most benign enzyme solvents. The conversion of phenolic acids through esterification alters their solubility and enhances their use as food antioxidant additives as well as their application in cosmetics. Read More

    [Research on ginseng trade competitiveness between China and Korea].
    Zhongguo Zhong Yao Za Zhi 2017 May;42(9):1803-1807
    State Key Laboratory Breeding Base of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijng 100700, China.
    Ginseng is one of China's valuable Chinese herbal medicines, with a long using history. Ginseng has worldwide reputation, and widely used in food, medicine, health products, cosmetics and other production. China and South Korea have a big ginseng industrial, and sharing half of the export market. Read More

    Application of in vitro skin penetration measurements to confirm and refine the quantitative skin sensitization risk assessment of methylisothiazolinone.
    Regul Toxicol Pharmacol 2017 Dec 6;91:197-207. Epub 2017 Nov 6.
    Procter & Gamble Services Company NV, Temselaan 100, B-1853 Strombeek-Bever, Belgium. Electronic address:
    Use of quantitative risk assessment (QRA) for assessing the skin sensitization potential of chemicals present in consumer products requires an understanding of hazard and product exposure. In the absence of data, consumer exposure is based on relevant habits and practices and assumes 100% skin uptake of the applied dose. To confirm and refine the exposure, a novel design for in vitro skin exposure measurements was conducted with the preservative, methylisothiazolinone (MI), in beauty care (BC) and household care (HHC) products using realistic consumer exposure conditions. Read More

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