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Dermatol Clin 2022 Jul 2;40(3):307-318. Epub 2022 Jun 2.

Office of Cosmetics and Colors, Center for Food Safety and Nutrition, US Food and Drug Administration, 5001 Campus Drive, HFS-100, College Park, MD 20740, USA.

In the United States, cosmetics are regulated under the Food, Drug, and Cosmetic Act and the Fair Packaging and Labeling Act. Accordingly, cosmetic ingredients, with the exception of color additives, are not subject to premarket approval. However, they must not be adulterated or misbranded. Read More

Actas Dermosifiliogr 2022 Jun 10;113(6):T550-T554. Epub 2022 May 10.

Servicio de Dermatología, Hospital General Universitario de Valencia, Valencia, Spain.

Background And Objective: Rosacea is a chronic acneiform skin disorder in which impaired skin barrier function can lead to sensitization to allergens. We aimed to analyze contact allergies in our patients with rosacea.

Material And Methods: Retrospective cohort study of all patients who underwent patch testing in our skin allergy clinic between May 1991 and May 2019. Read More

Polymers (Basel) 2022 Jun 18;14(12). Epub 2022 Jun 18.

Department of Food Science and Biotechnology, Dongguk University-Seoul, 32, Dongguk-ro, Ilsandong-gu, Goyang-si 10326, Gyeonggi-do, Korea.

This study extracted the mucilage from L. to observe its chemical and functional properties and suggest its possible applications in various fields. L. Read More

Polymers (Basel) 2022 Jun 9;14(12). Epub 2022 Jun 9.

Department of Industrial Engineering, Faculty of Engineering, King Abdulaziz University, P.O. Box 80204, Jeddah 21589, Saudi Arabia.

Due to the versatility of its features and capabilities, chitosan generated from marine crustacean waste is gaining importance and appeal in a wide variety of applications. It was initially used in pharmaceutical and medical applications due to its antibacterial, biocompatible, and biodegradable properties. However, as the demand for innovative materials with environmentally benign properties has increased, the application range of chitosan has expanded, and it is now used in a variety of everyday applications. Read More

Pharmaceutics 2022 Jun 8;14(6). Epub 2022 Jun 8.

Department of Clinical and Toxicological Analysis, Faculty of Pharmacy, Federal University of Bahia, Salvador 40170-115, Brazil.

The use of innate products for the fast and efficient promotion of healing process has been one of the biomedical sector's main bets for lesion treatment modernization process. The aim of this study was to develop and characterize bacterial cellulose-based (BC) wound dressings incorporated with green and red propolis extract (2 to 4%) and the active compounds -coumaric acid and biochanin A (8 to 16 mg). The characterization of the nine developed samples (one control and eight active wound dressings) evidenced that the mechanics, physics, morphological, and barrier properties depended not only on the type of active principle incorporated onto the cellulosic matrix, but also on its concentration. Read More

Pharmaceuticals (Basel) 2022 May 25;15(6). Epub 2022 May 25.

Department of Pharmaceutics, College of Pharmacy, Jazan University, Jazan 45142, Saudi Arabia.

The current review is based on the advancements in the field of natural therapeutic agents which could be utilized for a variety of biomedical applications and against various diseases and ailments. In addition, several obstacles have to be circumvented to achieve the desired therapeutic effectiveness, among which limited dissolution and/or solubility and permeability are included. To counteract these issues, several advancements in the field of natural therapeutic substances needed to be addressed. Read More

Molecules 2022 Jun 20;27(12). Epub 2022 Jun 20.

Department of Drug Sciences, University of Pavia, Via Taramelli 12, 27100 Pavia, Italy.

Mill. essential oil is mainly used in the cosmetics and perfumery industry, but it also finds application in the food industry as a flavoring agent. The chemical composition of essential oils is affected by environment, soil, harvesting technique, storage condition, and extraction methods. Read More

Molecules 2022 Jun 18;27(12). Epub 2022 Jun 18.

Institute of Natural Products and Cosmetics, Faculty of Biotechnology and Food Sciences, Lodz University of Technology, 90-537 Lodz, Poland.

Stinging nettle ( L.) is a common perennial herb well known for its therapeutic, cosmetic and food use. Despite the popularity of nettle hydrolate, there is currently no literature describing its composition; likewise, there is still a lack of research describing in detail the parameters of hydrolates in general. Read More

Molecules 2022 Jun 18;27(12). Epub 2022 Jun 18.

State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, China.

Metal organic frameworks (MOFs) are formed by self-assembly of metal ions and organic ligands. A special type of MOF called ZIF-8, which is formed by self-assembly of zinc ions and 2-methylimidazole, shows excellent stability in aqueous solutions and disintegrates under acidic conditions. These properties make ZIF-8 a suitable carrier material for pH-stimulated drug delivery systems. Read More

Molecules 2022 Jun 17;27(12). Epub 2022 Jun 17.

Production Systems Unit, Natural Resources Institute Finland, FI-00791 Helsinki, Finland.

Volatile organic compounds (VOC) affect the quality of indoor air. Terpenes and especially monoterpenes are the main molecules emitted from softwood material (coniferous species), which is widely used in construction. The corneal epithelium is one of the first human membranes to encounter VOCs in the air. Read More

Molecules 2022 Jun 15;27(12). Epub 2022 Jun 15.

Department of Agriculture and Animal Health, University of South Africa, Johannesburg 1709, South Africa.

This work presents the first report on the phytochemical investigation of Bernh. gum exudate. A known cardanol, 3-heptadec-12'--enyl phenol () and three new alk(en)ylhydroxycyclohexanes, namely, (1,3)-1,3-dihydroxy-3-[heptadec-12'()-enyl]cyclohexane () (1,2,345)-1,2,3,4,5-pentahydroxy-5-[octadec-13'()-enyl]cyclohexane () and (1,2,4)-1,2,4-trihydroxy-4-[heptadec-12'()-enyl]cyclohexane () were isolated from the gum. Read More

Int J Mol Sci 2022 Jun 16;23(12). Epub 2022 Jun 16.

Institute of Food Science Research (CIAL, CSIC-UAM, CEI UAM + CSIC), Nicolás Cabrera 9, 28049 Madrid, Spain.

In recent years, peptides have received increased interest in pharmaceutical, food, cosmetics, and various other fields [... Read More

Int J Mol Sci 2022 Jun 14;23(12). Epub 2022 Jun 14.

Vavilov Institute of General Genetics Russian Academy of Sciences, 119991 Moscow, Russia.

Formaldehyde (FA) is the simplest aldehyde present both in the environment and in living organisms. FA is an extremely reactive compound capable of protein crosslinking and DNA damage. For a long time, FA was considered a "biochemical waste" and a by-product of normal cellular metabolism, but in recent decades the picture has changed. Read More

Int J Mol Sci 2022 Jun 14;23(12). Epub 2022 Jun 14.

Laboratory of Chemistry and Environmental Toxicology, Department of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, 20156 Milan, Italy.

The risk-characterization of chemicals requires the determination of repeated-dose toxicity (RDT). This depends on two main outcomes: the no-observed-adverse-effect level (NOAEL) and the lowest-observed-adverse-effect level (LOAEL). These endpoints are fundamental requirements in several regulatory frameworks, such as the Registration, Evaluation, Authorization and Restriction of Chemicals (REACH) and the European Regulation of 1223/2009 on cosmetics. Read More

Genes (Basel) 2022 May 30;13(6). Epub 2022 May 30.

Key Laboratory of Horticultural Plant Biology, College of Horticulture and Forestry Sciences, Huazhong Agricultural University, Wuhan 430070, China.

Roses have high economic values as garden plants and for cut-flower and cosmetics industries. The growth and development of rose plants is affected by exposure to high temperature. Histone acetylation plays an important role in plant development and responses to various stresses. Read More

Biology (Basel) 2022 Jun 13;11(6). Epub 2022 Jun 13.

School of Food and Advanced Technology, Massey University, Palmerston North 4410, New Zealand.

Collagen is the most abundant structural protein in animals. It is the major component of skin. It finds uses in cosmetics, medicine, yarn production and packaging. Read More

Antioxidants (Basel) 2022 Jun 16;11(6). Epub 2022 Jun 16.

School of Biological Sciences and Technology, Chonnam National University, Gwangju 61186, Korea.

β-Carotene 15,15'-oxygenase (BCO1) and β-carotene 9',10'-oxygenase (BCO2) are potential producers of vitamin A derivatives, since they can catalyze the oxidative cleavage of dietary provitamin A carotenoids to retinoids and derivative such as apocarotenal. Retinoids are a class of chemical compounds that are vitamers of vitamin A or are chemically related to it, and are essential nutrients for humans and highly valuable in the food and cosmetics industries. β-carotene oxygenases (BCOs) from various organisms have been overexpressed in heterogeneous bacteria, such as , and their biochemical properties have been studied. Read More

Antioxidants (Basel) 2022 May 31;11(6). Epub 2022 May 31.

Department of Pharmacy, School of Health Sciences, University of Patras, 26504 Patras, Greece.

The aim of this study was the development of an efficient "green" extraction method of to produce antioxidant extracts and nutritious residual biomass. Twenty-one extraction methods were evaluated by measuring the reactivity with the Folin-Ciocalteu reagent: ultrasonication or maceration at different temperatures with different organic solvents, extraction at different pH values, enzyme-assisted extraction, encapsulation with β-cyclodextrin, and the use of natural deep eutectic solvents. Ultrasound-assisted extraction with ethanol or betaine: 1,2-propanediol in a molar ratio of 2:5 (BP) had optimal extractive capacity. Read More

Antioxidants (Basel) 2022 May 24;11(6). Epub 2022 May 24.

Institute of Bioscience and BioResources, National Research Council, Via Università 100, 80055 Portici, Italy.

Cultivated cardoon ( L. var ) is a Mediterranean traditional food crop. It is adapted to xerothermic conditions and also grows in marginal lands, producing a large biomass rich in phenolic bioactive metabolites and has therefore received attention for pharmaceutical, cosmetic and innovative materials applications. Read More

Animals (Basel) 2022 Jun 8;12(12). Epub 2022 Jun 8.

Institute of Biological Bases of Animal Production, University of Life Sciences in Lublin, 13 Akademicka St., 20-950 Lublin, Poland.

The available evidence on dogs' scent preferences is quite limited. The purpose of this study was to verify the canine response to selected odors that may also be preferred by humans. The experiment was performed using 14 adult dogs (10 female and 4 male) of different breeds, body size, and age (1-14 years). Read More

J Hazard Mater 2022 May 11;430:128459. Epub 2022 Feb 11.

NMPA Key Laboratory for Safety Evaluation of Cosmetics, Guangdong Provincial Key Laboratory of Tropical Disease Research, Department of Toxicology, School of Public Health, Southern Medical University, Guangzhou 510515, China. Electronic address:

With the prevalence of nanoplastics in daily life, human exposure is inevitable. However, whether and how nanoplastics cause neurotoxicity in humans remains obscure. Herein, we conducted a 28-day repeated dose oral toxicity study in C57BL/6 J mice exposed to 0. Read More

Dent Clin North Am 2022 Jul;66(3):489-501

Worldwide Laser Institute, Dallas, Texas, USA.

Smile design is an ongoing challenge in both dentistry and facial cosmetics surgery. Herein, some very common smile design scenarios are shared with six world known masters. Each case will be reviewed by 2 cosmetic dentists, 2 periodontists, and 2 oral and maxillofacial surgeons. Read More

Dent Clin North Am 2022 Jul 31;66(3):343-360. Epub 2022 May 31.

Oral and Maxillofacial Surgery Department, University of Louisville, Louisville, KY, USA.

The oral and maxillofacial surgeon (OMS) has the knowledge and skills to make drastic skeletal changes in favor of a more cosmetic smile. OMS can alter intraoral and extraoral soft tissues to make subtle or significant changes in facial cosmesis. This article provides an overview of the scope of the OMS in smile design. Read More

Toxics 2022 May 24;10(6). Epub 2022 May 24.

Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.

Gold nanomaterials (Au NMs) have been widely used in cosmetic products for improving the brightening, and reducing the wrinkling of, skin, etc.; however, the dermal safety of Au NMs is rarely concerned. A previous study found that cosmetics could enhance the toxicity of Au nanosheets, but different physicochemical properties of Au NMs will induce different interaction modes with ingredients of cosmetics, potentially leading to different toxicity profiles. Read More

Mar Drugs 2022 May 24;20(6). Epub 2022 May 24.

Animal and Fish Production Department, College of Agricultural and Food Sciences, King Faisal University, Al-Ahsa 31982, Saudi Arabia.

Since ancient times, seaweeds have been employed as source of highly bioactive secondary metabolites that could act as key medicinal components. Furthermore, research into the biological activity of certain seaweed compounds has progressed significantly, with an emphasis on their composition and application for human and animal nutrition. Seaweeds have many uses: they are consumed as fodder, and have been used in medicines, cosmetics, energy, fertilizers, and industrial agar and alginate biosynthesis. Read More

J Fungi (Basel) 2022 May 26;8(6). Epub 2022 May 26.

School of Cosmetic Science, Mae Fah Luang University, Chiang Rai 57100, Thailand.

Polysaccharides from (VVP) were investigated for their cosmetic-related activities and in vivo efficacy for use as a multifunctional active cosmetic ingredient. Three different polysaccharide extraction methods, including hot water shaking (HS), microwave-assisted (MA) and ultrasonic-assisted (UA), were used. Extractable yield, polysaccharide contents and biological activities, including antioxidant, anti-tyrosinase and anti-elastase activities, were compared. Read More

Gels 2022 May 30;8(6). Epub 2022 May 30.

Department of Pharmacy, Bahawalpur Medical and Dental College (BMDC), Bahawalpur 63100, Pakistan.

Background: Tocopherol acetate (TA) is known as a skin moisturizing and photoprotective agent. One major drawback with tocopherol and its derivatives remains its limited stability.

Aim: To develop highly stable TA-containing ethosomal gel (TAEG) as an advanced dosage form. Read More

Biosensors (Basel) 2022 May 31;12(6). Epub 2022 May 31.

Center of Excellence for Advanced Materials Research (CEAMR), King Abdulaziz University, P.O. Box 80203, Jeddah 21589, Saudi Arabia.

Here, a sensitive voltametric electrochemical sensor probe was fabricated to reliably trace the detection of L-aspartic acid in phosphate-buffered medium using a glassy carbon electrode (GCE) layered with a film of wet-chemically prepared AgO-doped ZnO nanosheets (NSs). EDS, FESEM, XPS, and X-ray diffraction analyses were implemented as characterizing tools of prepared NSs to confirm the structural and compositional morphology, binding energies of existing atoms, and the crystallinity of synthesized NSs. The differential pulse voltammetry (DPV) was applied to the trace detection of L-aspartic acid, and exhibited a wide detection range of 15. Read More

J Food Sci Technol 2022 Jul 30;59(7):2527-2534. Epub 2021 Jun 30.

Pharmacognosy Department, Faculty of Pharmacy, Cairo University, Cairo, 11562 Egypt.

Manuka honey (MH) stands out from other honey types as a unique super-food with clinically proven antimicrobial and wound healing activities. Its unique traits and the broad range of applications ( food, cosmetics, nutraceuticals /natural health products) have marked up its price 6 to 25 times than other honey types. Concurrent to the increased market demand, more fraudulence of MH emerged. Read More

BMC Oral Health 2022 Jun 22;22(1):248. Epub 2022 Jun 22.

Clinic of Conservative and Preventive Dentistry, Center for Dental Medicine, University of Zurich, 8032, Zurich, Switzerland.

Background: Diamond particles have recently been used as abrasives in toothpastes, which raises questions about its abrasive behaviour towards enamel. This study was carried out to investigate the abrasive enamel wear caused by three diamond-loaded toothpastes (Candida White Diamond: CWD, Swiss Smile Diamond Glow: SSDG, Emoform F Diamond: EFD) and to compare it with a traditional toothpaste with silica abrasive (Colgate Total Original CTO).

Methods: Eighty bovine enamel samples were divided into four groups (n = 20) and brushed for 21,600 cycles (60 cycles/min) for 6 h at 2. Read More