Ann Pharm Fr 2017 Jul 6. Epub 2017 Jul 6.

School of Cosmetic Science, Mae Fah Luang University, 57100 Chiang Rai, Thailand; Phytocosmetics and Cosmeceuticals Research Group, Mae Fah Luang University, 57100 Chiang Rai, Thailand.

Introduction: Scaphium scaphigerum or malva nut has long been served in Chinese medicine. However, the use of this herb in modern health care applications has, to date, been rarely reported.

Materials And Methods: Maceration of the herb in water afforded malva nut polysaccharide which was standardized. Read More

BMC Complement Altern Med 2017 Jul 5;17(1):355. Epub 2017 Jul 5.

Department of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, P.O. Box 7, Nablus, Palestine.

Background: Natural products have many uses and purposes, including those linked to pharmaceutics and cosmetics. The aim of this study was to investigate the use of natural remedies for the treatment of hair and scalp disorders in the West Bank, Palestine.

Methods: An ethnopharmacological survey of herbal remedies and other natural products used in cosmetics and cosmeceuticals was carried out in the West Bank, Palestine. Read More

J Cosmet Laser Ther 2017 Jun 28. Epub 2017 Jun 28.

a DERMATOLOGY, DR RMLH, PGIMER , NEW DELHI , India.

Facial warts are common cause of cosmetic concern and also affects the self-esteem of the affected patients. These are benign skin papillomas caused by human papillomavirus infections. Warts affecting the face are mainly due to HPV-3 and HPV-10. Read More

Mater Sci Eng C Mater Biol Appl 2017 Oct 10;79:581-589. Epub 2017 May 10.

Division of Nanoscience and Technology, Bharathidasan Institute of Technology, Anna University, Tiruchirappalli 620024, Tamil Nadu, India. Electronic address:

Nanocosmeceuticals are promising applications of nanotechnology in personal care industries. Zinc oxide is an inorganic material that is non-toxic and skin compatible with self-cleansing and microbicidal properties. Herein, exploitation of colloidal zinc oxide nanoparticles (ZnONps) as potent biomaterial for a topical formulation of cosmetic and dermatological significance is employed. Read More

Oxid Med Cell Longev 2017 23;2017:3631565. Epub 2017 May 23.

Application Technique Engineering Center of Natural Cosmeceuticals, College of Fuijan Province, Xiamen Medical College, Xiamen, Fujian 361023, China.

Folium Microcos (FM), the leaves of Microcos paniculata L., shows various biological functions including antioxidant activity and α-glucosidase inhibitory effect. However, its therapeutic potential in acute liver injury is still unknown. Read More

AMB Express 2017 Dec 5;7(1):114. Epub 2017 Jun 5.

Innovation Center for Holistic Health, Nutraceuticals and Cosmeceuticals, Faculty of Pharmacy, Chiang Mai University, Chiang Mai, 50200, Thailand.

Studies on phytochemical properties and bioactivities of rice bran revealed the wealth of natural complex antioxidant compounds. The composition and the properties of the rice bran get altered after fermentation by several microbes. This study was designed to optimize the black rice bran fermentation conditions for the total anthocyanin (ACN) content, total antioxidant properties, and relative activity of β-glucosidase (BGS) by Saccharomyces cerevisiae. Read More

Int J Mol Sci 2017 Jun 3;18(6). Epub 2017 Jun 3.

Department of Physiology and Developmental Biology and The Neuroscience Center, LS 4005, College of Life Sciences, Brigham Young University, Provo, UT 84602, USA.

Phytochemicals are botanical compounds used in dermatology applications as cosmeceuticals to improve skin health. Resveratrol and equol are two of the best-known polyphenolic or phytoestrogens having similar chemical structures and some overlapping biological functions to 17β-estradiol. Human skin gene expression was reviewed for 28 different biomarkers when resveratrol, 4' acetoxy resveratrol (4AR), R-equol, racemic equol or S-equol were tested. Read More

Mar Drugs 2017 May 18;15(5). Epub 2017 May 18.

Division of Bioengineering, Incheon National University, Incheon 406-772, Korea.

Marine fish provide a rich source of bioactive compounds such as proteins and peptides. The bioactive proteins and peptides derived from marine fish have gained enormous interest in nutraceutical, pharmaceutical, and cosmeceutical industries due to their broad spectrum of bioactivities, including antioxidant, antimicrobial, and anti-aging activities. Recently, the development of cosmeceuticals using marine fish-derived proteins and peptides obtained from chemical or enzymatical hydrolysis of fish processing by-products has increased rapidly owing to their activities in antioxidation and tissue regeneration. Read More

J Cosmet Laser Ther 2017 May 11:1-4. Epub 2017 May 11.

a Kasturba Medical College (KMC), Manipal University , Manipal , India.

Numerous skin lesions have been commonly observed in individuals with diabetes mellitus. The common skin manifestations of diabetes mellitus are erythrasma, xanthomatosis, xanthelasma, phycomycetes and cutaneous infections like furuncolosis, candidiasis, carbuncle, dermatophytosis, etc. Diabetic dermopathy is the most common skin lesion found in patients with diabetes. Read More

J Environ Sci Health A Tox Hazard Subst Environ Eng 2017 May 10:1-5. Epub 2017 May 10.

d Department of Biological Science and Technology , China University of Science and Technology , Taipei , Taiwan.

A novel two-chamber microbial fuel cell (MFC) operation with a continuous anaerobic-aerobic decolorization system was developed to improve the degradation of the triphenylmethane dye, Victoria blue R (VBR). In addition, bioelectricity was generated during the VBR degradation process, and the operation parameters were optimized. The results indicated that the VBR removal efficiency and electricity generation were affected by the VBR concentration, liquid retention time (LRT), external resistance, gas retention time (GRT), and shock loading. Read More

Food Res Int 2016 Nov 10;89(Pt 1):432-438. Epub 2016 Aug 10.

Research Center for Agricultural Technology (CITA-A), Department of Technological Sciences and Development (DCTD), University of Azores, 9501-801 Ponta Delgada, S. Miguel, Azores, Portugal.

This study presents, for the first time, the nutritional and health promoting aspects of four selected Azorean macroalgae (Ulva compressa, Ulva rigida, Gelidium microdon and Pterocladiella capillacea) in terms of total lipids, fatty acids (FA) profile, n6/n3 and hypocholesterolemic (h)/hypercholesterolemic (H) FA ratios, minerals, total essential amino acids (AA), anti-ageing and anti-phenylketonuria AA content, coenzyme Q10, α-tocopherol, total phenolics, antioxidant properties and energy value, on a dry weight basis. The results revealed low lipid content (1.02-4. Read More

Mar Drugs 2017 Apr 12;15(4). Epub 2017 Apr 12.

Stazione Zoologica Anthon Dohrn, 80121 Naples, Italy.

The oceans encompass a wide range of habitats and environmental conditions, which host a huge microbial biodiversity. The unique characteristics of several marine systems have driven a variety of biological adaptations, leading to the production of a large spectrum of bioactive molecules. Fungi, fungi-like protists (such as thraustochytrids) and bacteria are among the marine organisms with the highest potential of producing bioactive compounds, which can be exploited for several commercial purposes, including cosmetic and cosmeceutical ones. Read More

Front Biosci (Schol Ed) 2017 Jun 1;9:319-342. Epub 2017 Jun 1.

School of Engineering and Science, Tecnologico de Monterrey, Campus Monterrey, Ave. Eugenio Garza Sada 2501, Monterrey, N.L., CP 64849, Mexico,

  From the past several years, algal biotechnology has gained noticeable interests among research-based organizations and industrial sectors. Recent studies have provided considerable evidence that microalgae-derived bioactive compounds could play a vital role in bio- and non-bio sectors of the modern world. Microalgae-based industrial exploitability ranges from basic biomass-based food and feeds nutraceuticals to high-value pharmaceuticals, cosmeceuticals, ecological and biomedical applications. Read More

Daru 2017 Apr 12;25(1). Epub 2017 Apr 12.

Department of Toxicology and Pharmacology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.

The overwhelming population growth in recent decades and water crisis along with limited and uneven geographical distribution of fresh water resources is a growing challenge for the economic and human development. Wastewater reclamation and use could be an alternative for intact water sources and a promising solution to water scarcity and unequal distribution. However, wastewater is a double-edged resource both as an accessible water source for food production and human usage and concurrently may carry uncharacterized content with unknown toxicological profile causing acute or long-term health risks. Read More

J Drugs Dermatol 2017 Apr;16(4):358-363

J Cosmet Laser Ther 2017 Apr 7:1-3. Epub 2017 Apr 7.

a Hospital Federal da Lagoa , Rio de Janeiro , Brazil.

Vascular lesions such as hemangiomas can be found in the oral cavity. Some therapeutic modalities can be used in the treatment of these lesions and Nd:YAG 1064 nm long pulse laser shows good results with easy application, fewer complications and satisfactory results. This study describes the technique and outcome of a case of hemangioma located on the tongue treated with Nd:YAG laser. Read More

Dermatol Surg 2017 Apr;43(4):475-484

*Department of Dermatology, University of Utah School of Medicine, Salt Lake City, Utah;†Goldman, Butterwick, Groff, Fabi & Wu, Cosmetic Laser Dermatology, San Diego, California;‡Department of Dermatology, University of California, San Diego, California.

Background: Aging is a multifactorial process and depends on both intrinsic and extrinsic factors. Procedural options for diminishing signs of intrinsic aging and cosmetic rejuvenation have expanded dramatically. However, less attention is paid to counseling patients on options for mitigating extrinsic factors related to aging. Read More

J Cutan Med Surg 2017 Feb 1:1203475417690306. Epub 2017 Feb 1.

2 Department of Dermatology & Skin Science, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.

Introduction: First Nations people have a long history of working with medicinal plants used to treat skin diseases. The purpose was to assess the dermatologic therapeutic potential of western red cedar, white spruce, birch, balsam poplar, and black spruce.

Methods: Based on expert recommendations, 5 trees were selected that were used in First Nations medicine for cutaneous healing and have potential and/or current application to dermatology today. Read More

J Cutan Med Surg 2016 Dec 1:1203475416683390. Epub 2016 Dec 1.

2 The Department of Dermatology & Skin Science, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.

Introduction: Plants and algae have played a central role in the treatment of skin conditions in both traditional First Nations healing and in modern dermatology. The objective of this study was to examine the evidence supporting the dermatological use of seaweed, witch hazel, bearberry, and mayapple.

Methods: Four plants and algae used in traditional First Nations treatments of skin disease were selected based on expert recommendations. Read More

Clin Dermatol 2017 Mar - Apr;35(2):213-217. Epub 2016 Oct 27.

Consulting Professor, Department of Dermatology, Duke University School of Medicine, Durham, North Carolina. Electronic address:

Patients with rosacea present a challenge to the dermatologist, as they typically possess sensitive skin, need facial Demodex and bacterial colonization control, exhibit vasomotor instability, require camouflaging of telangiectatic mats, and desire prescription treatment. Currently available pharmaceuticals are aimed at inflammation reduction, primarily with the use of topical and oral antibiotics. Recently, vasoconstrictor formulations have emerged, but these drugs have only a temporary effect and improve appearance without addressing the underlying cause, which remains largely unknown. Read More

J Biosci Bioeng 2017 Jun 21;123(6):679-684. Epub 2017 Feb 21.

Department of Biological Science and Technology, China University of Science and Technology, No. 245, Sec. 3, Academia Rd., Taipei City 11581, Taiwan. Electronic address:

Angelica dahurica root (ADR), which shows strong antioxidant activity, is used in Chinese medicine. This study evaluated the tyrosinase inhibitory and antioxidant activities of ADR extracts fermented by four different probiotic bacteria: Bifidobacterium bifidum, Bifidobacterium lactis, Lactobacillus acidophilus, and Lactobacillus brevis. The ADR was first extracted using distilled water, 70% ethanol, and ethyl acetate, and then fermented by probiotic bacteria. Read More

Pharmacognosy Res 2017 Jan-Mar;9(1):39-45

Master of Science in Biotechnology Program, Faculty of Biotechnology, Atma Jaya Catholic University, Jakarta 12930, Indonesia; Medicine Program, Faculty of Medicine, Atma Jaya Catholic University, Jakarta 14440, Indonesia.

Background: Cosmeceuticals refer to natural cosmetics with medical-like benefits due to their bioactive contents. Sugar palm fruit (Arenga pinnata) extract has been claimed for its anti-aging effect in vitro. However, its active compounds for cosmeceuticals is still unclear. Read More

Molecules 2017 Feb 13;22(2). Epub 2017 Feb 13.

Mountain Research Centre (CIMO), ESA, Polytechnic Institute of Bragança, Campus de Santa Apolónia, 1172, 5300-253 Bragança, Portugal.

Bioactive compounds from natural sources, due to their widely-recognized benefits, have been exploited as cosmeceutical ingredients. Among them, phenolic acids emerge with a very interesting potential. In this context, this review analyzes hydroxycinnamic acids and their derivatives as multifunctional ingredients for topical application, as well as the limitations associated with their use in cosmetic formulations. Read More

J Cosmet Laser Ther 2017 Aug 6;19(4):232-236. Epub 2017 Feb 6.

d Private Practice , Tehran , Iran.

Introduction: One of the most important innovative methods for tissue repair promotion is therapeutic lasers with photobiomodulution effects. The aim of this study was to investigate the effect of four different wavelengths of therapeutic laser (405, 532, 660 and 810 nm) on healing of third-degree burns from both clinical and pathological standpoints in rats.

Materials And Methods: 60 male Wistar rats were used. Read More

J Cosmet Laser Ther 2017 Aug 2;19(4):215-218. Epub 2017 Feb 2.

a Department of Plastic , Reconstructive and Aesthetic Surgery, Bezmialem Medical School, Bezmialem Vakif University , Istanbul , Turkey.

Background: Gynecomastia, as a most common benign condition, represents itself as the enlargement of the male breast and also nipple-areola complex as the severity of the condition increases. With this study, we aimed to clarify the effects of 980-nm diode laser on nipple-areola complex (NAC).

Objectives: Although numerous open techniques have been described to correct gynecomastia, nowadays trends have shifted to minimally invasive techniques such as laser-assisted lipolysis (LAL). Read More

Contact Dermatitis 2017 Feb;76(2):126-128

Dermatology Unit, Clinics Hospital, Federal University of Minas Gerais, Belo Horizonte, Brazil.

Am J Clin Dermatol 2017 Apr;18(2):159-163

Department of Dermatology, Penn State/Hershey Medical Center, HU14, 500 University Drive, Hershey, PA, 17022, USA.

The use of cosmeceuticals by patients with acne is common; however, their role is unclear and confusing, with many asking, "Do they really help acne?" Cosmeceuticals are intermediate products between prescription medications and cosmetics, available to consumers over the counter. These products are popular and may be used without the direct supervision of a dermatologist, creating a practice gap in educating patients. Herein, a variety of cosmeceuticals are discussed, including retinoids, niacinamide, and glycolic acid. Read More

Ann Pharm Fr 2017 May 14;75(3):189-195. Epub 2016 Dec 14.

School of Cosmetic Science, Mae Fah Luang University, 333, Tasud Muang, 57100 Chiang Rai, Thailand; Phytocosmetics and Cosmeceuticals Research Group, Mae Fah Luang University, 333, Tasud Muang, 57100 Chiang Rai, Thailand. Electronic address:

Introduction: The efficacy of tea seed oil to clean foundation and eyeliner was evaluated. The safe and efficient tea seed oil makeup remover was developed.

Materials And Methods: In vitro cleansing efficacy of makeup remover was UV-spectrophotometric validated. Read More

Nurs Womens Health 2017 Dec 2016 - Jan;20(6):609-613

Women are inundated with advertisements for products promising younger-looking, healthier skin. The truth is that many of these products can be expensive and produce results that do not live up to the claims. Health care providers can educate women about proven best practices and how to evaluate products' claims of benefits. Read More

Semin Cutan Med Surg 2016 Dec;35(4):233-237

Baumann Cosmetic and Research Institute, Miami, Florida, USA.

Patients with skin of color have similar skin care needs as lighter-skin patients. However, they are less likely to use sun protection on a daily basis, which leads to an increased risk of dyschromia, skin cancer, and other disorders. This article discusses the importance of a correct and consistent skin care regimen and the various cutaneous issues that should be considered when prescribing a skin care regimen for patients with darker skin types. Read More

Int J Biol Macromol 2017 Mar 30;96:282-301. Epub 2016 Nov 30.

Institute of Chemistry, Government College University, Faisalabad 38030, Pakistan.

Carrageenan is a natural polysaccharide extracted from edible red seaweeds of Rhodophycea class. It has been used as a viscosity increasing or gelling agent for prolonged and controlled drug release, food, pharmaceuticals and other industries. However, in spite of wide range of applications, carrageenan has some drawbacks and adverse effects on the biological systems, so its modifications with natural and synthetic polymers are carried out. Read More

BMC Complement Altern Med 2016 Dec 3;16(1):497. Epub 2016 Dec 3.

Department of Obstetrics & Gynecology, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand.

Background: Natural products made from plant sources have been used in a variety of cosmetic applications as a source of nutrition and as a whitening agent. The flowers of Cassia fistula L, family Fabaceae, have been used as a traditional medicine for skin diseases and wound healing and have been reported to possess anti-oxidant properties. The anti-aging effect of C. Read More

J Cosmet Laser Ther 2017 Apr 1;19(2):83-88. Epub 2017 Feb 1.

c University Hospital of Basel , Switzerland.

Background: To date, no studies compared curative effects of thermal lesions in deep and superficial dermal layers in the same patient (face-split study).

Objective: To evaluate skin laxity effects of microneedle fractional radiofrequency induced thermal lesions in different dermal layers.

Methods And Materials: 13 patients underwent three sessions of a randomized face-split microneedle fractional radiofrequency system (MFRS) treatment of deep dermal and superficial dermal layer. Read More

Recent Pat Biotechnol 2017 ;11(1):3-19

CSIR-URDIP, Tapovan, S.No.113, 114, NCL Campus, Pashan, Pune 411008, Maharashtra. India.

Background: Saffron (Crocus sativus L.) has a long history of use as a food additive and a traditional medicine for treating a number of disorders. Prominent bioactives of saffron are crocin, crocetin and safranal. Read More

J Cosmet Laser Ther 2017 Apr 25;19(2):124-126. Epub 2017 Jan 25.

a Department of Dermatology , Tri-Service General Hospital, National Defense Medical Center , Taipei , Taiwan.

Filler migration is a potential complication following the injection of multiple fillers. With the increasing popularity of multiple filler injections, migrated granulomas should be an essential differential diagnosis for newly growing facial lumps. It is important for all physicians to be aware that complication induced by dermal fillers can occur in locations other than the planned injected sites. Read More

J Cosmet Laser Ther 2017 Apr 25;19(2):93-99. Epub 2017 Jan 25.

a Department of Dermatology and Cutaneous Surgery , University of Miami Miller School of Medicine , Miami , FL , USA.

Alopecia areata is a form of non-scarring alopecia that results from a hyperactive immune response of T cells against hair follicles. Many patients with visible hair loss experience psychological and emotional distress, as a result of their cosmetic disfigurement, and frequently seek treatment. However, existing treatment methods, such as corticosteroids, topical irritants, sensitizing agents, immunosuppressants, and psoralen plus ultraviolet light A, may result in various adverse effects and often lack efficacy. Read More

Int J Biol Macromol 2017 Jan 3;94(Pt A):10-27. Epub 2016 Oct 3.

Institute of Chemistry, Government College University, Faisalabad 38030, Pakistan. Electronic address:

Exopolysaccharides are synthesized by bacteria and secreted into the external environment and they may be homopolymeric or heteropolymeric in configuration. They are believed to protect bacterial cells from heavy metals, desiccation or other environmental effect. EPS exhibit antitumor, anti-HIV, emulsion stabilization capacity, shear-thinning activity, suspension ability, high viscosities, excellent biocompatibility, high biodegradability and immunomodulatory properties. Read More

Mar Drugs 2016 Oct 20;14(10). Epub 2016 Oct 20.

School of Food Science and Engineering, South China University of Technology, Wushan Rd. 381, Guangzhou 510641, China.

Industrial microalgae, as a big family of promising producers of renewable biomass feedstock, have been commercially exploited for functional food, living feed and feed additives, high-value chemicals in nutraceuticals, cosmeceuticals, and chemical reagents. Recently, microalgae have also been considered as a group that might play an important role in biofuel development and environmental protection. Almost all current products of industrial microalgae are derived from their biomass; however, large amounts of spent cell-free media are available from mass cultivation that is mostly unexploited. Read More

J Cosmet Laser Ther 2017 Feb 2;19(1):43-48. Epub 2016 Dec 2.

b Department of Dermatology , Seoul St. Mary's Hospital , Seoul , Republic of Korea.

Background: Polydeoxyribonucleotide (PDRN) is an active compound that can promote wound healing. PDRN stimulates wound healing by enhancing angiogenesis and increasing fibroblast growth rates. Laser skin resurfacing is a popular cosmetic procedure for skin rejuvenation. Read More

Molecules 2016 Oct 14;21(10). Epub 2016 Oct 14.

Mountain Research Centre (CIMO), ESA, Polytechnic Institute of Bragança, Campus de Santa Apolónia, 1172, 5300-253 Bragança, Portugal.

The cosmetic industry is in a constant search for natural compounds or extracts with relevant bioactive properties, which became valuable ingredients to design cosmeceutical formulations. Mushrooms have been markedly studied in terms of nutritional value and medicinal properties. However, there is still slow progress in the biotechnological application of mushroom extracts in cosmetic formulations, either as antioxidants, anti-aging, antimicrobial, and anti-inflammatory agents or as hyperpigmentation correctors. Read More

J Ethnopharmacol 2016 Dec 6;193:607-616. Epub 2016 Oct 6.

School of Cosmetic Science, Mae Fah Luang University, Chiang Rai, 57100 Thailand; Phytocosmetics and Cosmeceuticals Research Group, Mae Fah Luang University, Chiang Rai 57100, Thailand.

Ethnopharmacological Relevance: While rice is one of the most important global staple food sources its extracts have found many uses as the bases of herbal remedies. Rice extracts contain high levels of phenolic compounds which are known to be bioactive, some of which show cutaneous benefits and activity towards skin disorders. This study highlights an assessment of the cellular activity and clinical efficacy of rice panicle extract, providing necessary information relevant to the development of new cosmetic products. Read More

Sensors (Basel) 2016 Aug 16;16(8). Epub 2016 Aug 16.

Department of Biological Science and Technology, China University of Science and Technology, Taipei 11581, Taiwan.

Fast hexavalent chromium (Cr(VI)) determination is important for environmental risk and health-related considerations. We used a microbial fuel cell-based biosensor inoculated with a facultatively anaerobic, Cr(VI)-reducing, and exoelectrogenic Ochrobactrum anthropi YC152 to determine the Cr(VI) concentration in water. The results indicated that O. Read More

Aesthet Surg J 2017 Jan 16;37(1):71-83. Epub 2016 Aug 16.

Dr Sasaki is a Clinical Professor, Loma Linda Medical University Center, Loma Linda, CA

Background: Aesthetic micro-needling (MN) has demonstrated skin permeability to cosmeceutical ingredients and platelet-rich plasma by creating reversible micro-channels in the skin.

Objectives: The purposes of this study were to determine: (1) actual needle depth-penetrations by adjusting needle lengths in a disposable tip of an electric MN device; (2) time-dependent passage of pigment and platelets; and (3) safety and efficacy profiles in patients.

Methods: Excised micro-needled pre-auricular skin was used to determine actual depths of tissue penetration with six needle lengths, and the presence of massaged pigment particles (histological examination) and fluorescein-labeled platelets (confocal laser microscopy) in 1 mm depth micro-channels over an hour. Read More

Ageing Res Rev 2016 Nov 9;31:36-54. Epub 2016 Aug 9.

Department of Physiology and Developmental Biology and The Neuroscience Center, Brigham Young University, Provo, UT 84602, USA. Electronic address:

Oxygen in biology is essential for life. It comes at a cost during normal cellular function, where reactive oxygen species (ROS) are generated by oxidative metabolism. Human skin exposed to solar ultra-violet radiation (UVR) dramatically increases ROS production/oxidative stress. Read More

J Cosmet Dermatol 2016 Dec 6;15(4):527-539. Epub 2016 Aug 6.

Department of Dermatology, Frimley Park Hospital NHS Foundation Trust, Frimley, UK.

Facial rejuvenation can be categorized into skincare and facial contouring. Research and development of cosmeceuticals is aimed at addressing the major signs of photoaging: wrinkles, dyschromia, and sallowness. Assessment of photoaging comes in clinical and photographic forms; a photonumeric scale developed by Griffiths et al. Read More

Indian J Dermatol Venereol Leprol 2017 Jan-Feb;83(1):9-18

Department of Dermatology, Goa Medical College, Bambolim, Goa, India.

Peptides are known to have diverse biological roles, most prominently as signaling/regulatory molecules in a broad variety of physiological processes including defense, immunity, stress, growth, homeostasis and reproduction. These aspects have been used in the field of dermatology and cosmetology to produce short, stable and synthetic peptides for extracellular matrix synthesis, pigmentation, innate immunity and inflammation. The evolution of peptides over the century, which started with the discovery of penicillin, has now extended to their usage as cosmeceuticals in recent years. Read More

Sci Rep 2016 Jul 18;6:29969. Epub 2016 Jul 18.

Department of Microbiology and Immunology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.

Without a vaccine, hepatitis C virus (HCV) remains a significant threat, putting 170-300 million carriers worldwide at risk of cirrhosis and hepatocellular carcinoma. Although the direct-acting antivirals targeting HCV replication have revolutionized the treatment of hepatitis C, several obstacles persist, including resistance development, potential side-effects, and the prohibitive cost that limits their availability. Furthermore, treatment of HCV re-infection in liver transplantation remains a significant challenge. Read More

J Cutan Aesthet Surg 2016 Apr-Jun;9(2):85-92

Dr SN Wong Skin, Hair, Nails and Laser Specialist Clinic, Mt Elizabeth Medical Centre, Singapore.

Conventional acne treatment presents several challenges such as intolerable side effects and antibiotic resistance. Dermocosmetic products may be used to reduce these unwanted effects. Dermocosmetics include skin cleansers, topical sebum-controllers, skin antimicrobial/anti-inflammatory agents, moisturizers, sunscreens, and camouflage products. Read More

J Cutan Aesthet Surg 2016 Apr-Jun;9(2):65-72

TOC Eye and Face, Austin, USA.

Infraorbital dark circles represent a common and multifactorial challenge in the world of aesthetic medicine and are the result of a variety of factors including deep facial anatomy, soft tissue changes, as well as contributions from the skin. A variety of treatment options exist, and a customised management strategy can be developed for the particular anatomic changes present. A literature search using MEDLINE and non-MEDLINE sources was performed utilising keywords including: 'Dark circles' 'infraorbital dark circles', 'infraorbital pigment', 'under-eye circles' and 'lower eyelid bags'. Read More

J Drugs Dermatol 2016 Jul;15(7):863-8

Consumers are increasingly interested in over-the-counter skin care products that can improve the appearance of photodamaged and aging skin. This 10-week, open-label, single- center study enrolled 25 subjects with mild to moderate hyperpigmentation and other clinical stigmata of cutaneous aging including fine lines, sallowness, lack of clarity, and wrinkling. Their mean age was 53. Read More