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    275 results match your criteria Cosmeceuticals

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    Marine Microbial-Derived Molecules and Their Potential Use in Cosmeceutical and Cosmetic Products.
    Mar Drugs 2017 Apr 12;15(4). Epub 2017 Apr 12.
    Stazione Zoologica Anthon Dohrn, 80121 Naples, Italy.
    The oceans encompass a wide range of habitats and environmental conditions, which host a huge microbial biodiversity. The unique characteristics of several marine systems have driven a variety of biological adaptations, leading to the production of a large spectrum of bioactive molecules. Fungi, fungi-like protists (such as thraustochytrids) and bacteria are among the marine organisms with the highest potential of producing bioactive compounds, which can be exploited for several commercial purposes, including cosmetic and cosmeceutical ones. Read More

    High-value compounds from microalgae with industrial exploitability - A review.
    Front Biosci (Schol Ed) 2017 Jun 1;9:319-342. Epub 2017 Jun 1.
    School of Engineering and Science, Tecnologico de Monterrey, Campus Monterrey, Ave. Eugenio Garza Sada 2501, Monterrey, N.L., CP 64849, Mexico,
      From the past several years, algal biotechnology has gained noticeable interests among research-based organizations and industrial sectors. Recent studies have provided considerable evidence that microalgae-derived bioactive compounds could play a vital role in bio- and non-bio sectors of the modern world. Microalgae-based industrial exploitability ranges from basic biomass-based food and feeds nutraceuticals to high-value pharmaceuticals, cosmeceuticals, ecological and biomedical applications. Read More

    Health risks associated with the pharmaceuticals in wastewater.
    Daru 2017 Apr 12;25(1). Epub 2017 Apr 12.
    Department of Toxicology and Pharmacology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
    The overwhelming population growth in recent decades and water crisis along with limited and uneven geographical distribution of fresh water resources is a growing challenge for the economic and human development. Wastewater reclamation and use could be an alternative for intact water sources and a promising solution to water scarcity and unequal distribution. However, wastewater is a double-edged resource both as an accessible water source for food production and human usage and concurrently may carry uncharacterized content with unknown toxicological profile causing acute or long-term health risks. Read More

    TREATMENT OF VASCULAR LESIONS LOCATED IN THE LIP AND IN THE ORAL CAVITY WITH ND-YAG LASER.
    J Cosmet Laser Ther 2017 Apr 7. Epub 2017 Apr 7.
    a Hospital Federal da Lagoa , Rio de Janeiro, Brazil.
    Vascular lesions are common complaints reported in clinics and patients seeking treatment for aesthetic or functional issues. Vascular lesions such as hemangiomas can be found in the oral cavity and some therapeutic modalities can be used in the treatment of these lesions, which the Nd: YAG laser shows good results for easy implementation, fewer complications and satisfactory results. This study describes technique and outcome of a case of hemangioma located on the tongue treated with Nd: YAG laser. Read More

    A Holistic Approach to Antiaging as an Adjunct to Antiaging Procedures: A Review of the Literature.
    Dermatol Surg 2017 Apr;43(4):475-484
    *Department of Dermatology, University of Utah School of Medicine, Salt Lake City, Utah;†Goldman, Butterwick, Groff, Fabi & Wu, Cosmetic Laser Dermatology, San Diego, California;‡Department of Dermatology, University of California, San Diego, California.
    Background: Aging is a multifactorial process and depends on both intrinsic and extrinsic factors. Procedural options for diminishing signs of intrinsic aging and cosmetic rejuvenation have expanded dramatically. However, less attention is paid to counseling patients on options for mitigating extrinsic factors related to aging. Read More

    Botanicals With Dermatologic Properties Derived From First Nations Healing.
    J Cutan Med Surg 2017 Feb 1:1203475417690306. Epub 2017 Feb 1.
    2 Department of Dermatology & Skin Science, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.
    Introduction: First Nations people have a long history of working with medicinal plants used to treat skin diseases. The purpose was to assess the dermatologic therapeutic potential of western red cedar, white spruce, birch, balsam poplar, and black spruce.

    Methods: Based on expert recommendations, 5 trees were selected that were used in First Nations medicine for cutaneous healing and have potential and/or current application to dermatology today. Read More

    Botanicals With Dermatologic Properties Derived From First Nations Healing.
    J Cutan Med Surg 2016 Dec 1:1203475416683390. Epub 2016 Dec 1.
    2 The Department of Dermatology & Skin Science, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.
    Introduction: Plants and algae have played a central role in the treatment of skin conditions in both traditional First Nations healing and in modern dermatology. The objective of this study was to examine the evidence supporting the dermatological use of seaweed, witch hazel, bearberry, and mayapple.

    Methods: Four plants and algae used in traditional First Nations treatments of skin disease were selected based on expert recommendations. Read More

    Cosmeceuticals for rosacea.
    Clin Dermatol 2017 Mar - Apr;35(2):213-217. Epub 2016 Oct 27.
    Consulting Professor, Department of Dermatology, Duke University School of Medicine, Durham, North Carolina. Electronic address:
    Patients with rosacea present a challenge to the dermatologist, as they typically possess sensitive skin, need facial Demodex and bacterial colonization control, exhibit vasomotor instability, require camouflaging of telangiectatic mats, and desire prescription treatment. Currently available pharmaceuticals are aimed at inflammation reduction, primarily with the use of topical and oral antibiotics. Recently, vasoconstrictor formulations have emerged, but these drugs have only a temporary effect and improve appearance without addressing the underlying cause, which remains largely unknown. Read More

    Evaluation of tyrosinase inhibitory and antioxidant activities of Angelica dahurica root extracts for four different probiotic bacteria fermentations.
    J Biosci Bioeng 2017 Feb 18. Epub 2017 Feb 18.
    Department of Biological Science and Technology, China University of Science and Technology, No. 245, Sec. 3, Academia Rd., Taipei City 11581, Taiwan. Electronic address:
    Angelica dahurica root (ADR), which shows strong antioxidant activity, is used in Chinese medicine. This study evaluated the tyrosinase inhibitory and antioxidant activities of ADR extracts fermented by four different probiotic bacteria: Bifidobacterium bifidum, Bifidobacterium lactis, Lactobacillus acidophilus, and Lactobacillusbrevis. The ADR was first extracted using distilled water, 70% ethanol, and ethyl acetate, and then fermented by probiotic bacteria. Read More

    Cosmeceutical Effects of Galactomannan Fraction from Arenga pinnata Fruits In vitro.
    Pharmacognosy Res 2017 Jan-Mar;9(1):39-45
    Master of Science in Biotechnology Program, Faculty of Biotechnology, Atma Jaya Catholic University, Jakarta 12930, Indonesia; Medicine Program, Faculty of Medicine, Atma Jaya Catholic University, Jakarta 14440, Indonesia.
    Background: Cosmeceuticals refer to natural cosmetics with medical-like benefits due to their bioactive contents. Sugar palm fruit (Arenga pinnata) extract has been claimed for its anti-aging effect in vitro. However, its active compounds for cosmeceuticals is still unclear. Read More

    Evaluation of therapeutic laser influences on the healing of third-degree burns in rats according to different wavelengths.
    J Cosmet Laser Ther 2017 Feb 6:1-5. Epub 2017 Feb 6.
    d Private Practice , Tehran , Iran.
    Introduction: One of the most important innovative methods for tissue repair promotion is therapeutic lasers with photobiomodulution effects. The aim of this study was to investigate the effect of four different wavelengths of therapeutic laser (405, 532, 660 and 810 nm) on healing of third-degree burns from both clinical and pathological standpoints in rats.

    Materials And Methods: 60 male Wistar rats were used. Read More

    Effects of laser-assisted lipolysis on nipple-areola complex.
    J Cosmet Laser Ther 2017 Feb 2:1-4. Epub 2017 Feb 2.
    a Department of Plastic , Reconstructive and Aesthetic Surgery, Bezmialem Medical School, Bezmialem Vakif University , Istanbul , Turkey.
    Background: Gynecomastia, as a most common benign condition, represents itself as the enlargement of the male breast and also nipple-areola complex as the severity of the condition increases. With this study, we aimed to clarify the effects of 980-nm diode laser on nipple-areola complex (NAC).

    Objectives: Although numerous open techniques have been described to correct gynecomastia, nowadays trends have shifted to minimally invasive techniques such as laser-assisted lipolysis (LAL). Read More

    The Use of Cosmeceuticals in Acne: Help or Hoax?
    Am J Clin Dermatol 2017 Apr;18(2):159-163
    Department of Dermatology, Penn State/Hershey Medical Center, HU14, 500 University Drive, Hershey, PA, 17022, USA.
    The use of cosmeceuticals by patients with acne is common; however, their role is unclear and confusing, with many asking, "Do they really help acne?" Cosmeceuticals are intermediate products between prescription medications and cosmetics, available to consumers over the counter. These products are popular and may be used without the direct supervision of a dermatologist, creating a practice gap in educating patients. Herein, a variety of cosmeceuticals are discussed, including retinoids, niacinamide, and glycolic acid. Read More

    Development and efficacy assessments of tea seed oil makeup remover.
    Ann Pharm Fr 2017 May 14;75(3):189-195. Epub 2016 Dec 14.
    School of Cosmetic Science, Mae Fah Luang University, 333, Tasud Muang, 57100 Chiang Rai, Thailand; Phytocosmetics and Cosmeceuticals Research Group, Mae Fah Luang University, 333, Tasud Muang, 57100 Chiang Rai, Thailand. Electronic address:
    Introduction: The efficacy of tea seed oil to clean foundation and eyeliner was evaluated. The safe and efficient tea seed oil makeup remover was developed.

    Materials And Methods: In vitro cleansing efficacy of makeup remover was UV-spectrophotometric validated. Read More

    Skin Care for Women.
    Nurs Womens Health 2017 Dec 2016 - Jan;20(6):609-613
    Women are inundated with advertisements for products promising younger-looking, healthier skin. The truth is that many of these products can be expensive and produce results that do not live up to the claims. Health care providers can educate women about proven best practices and how to evaluate products' claims of benefits. Read More

    Cosmeceuticals in skin of color.
    Semin Cutan Med Surg 2016 Dec;35(4):233-237
    Baumann Cosmetic and Research Institute, Miami, Florida, USA.
    Patients with skin of color have similar skin care needs as lighter-skin patients. However, they are less likely to use sun protection on a daily basis, which leads to an increased risk of dyschromia, skin cancer, and other disorders. This article discusses the importance of a correct and consistent skin care regimen and the various cutaneous issues that should be considered when prescribing a skin care regimen for patients with darker skin types. Read More

    A review on synthesis, properties and applications of natural polymer based carrageenan blends and composites.
    Int J Biol Macromol 2017 Mar 30;96:282-301. Epub 2016 Nov 30.
    Institute of Chemistry, Government College University, Faisalabad 38030, Pakistan.
    Carrageenan is a natural polysaccharide extracted from edible red seaweeds of Rhodophycea class. It has been used as a viscosity increasing or gelling agent for prolonged and controlled drug release, food, pharmaceuticals and other industries. However, in spite of wide range of applications, carrageenan has some drawbacks and adverse effects on the biological systems, so its modifications with natural and synthetic polymers are carried out. Read More

    Anti-aging and tyrosinase inhibition effects of Cassia fistula flower butanolic extract.
    BMC Complement Altern Med 2016 Dec 3;16(1):497. Epub 2016 Dec 3.
    Department of Obstetrics & Gynecology, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand.
    Background: Natural products made from plant sources have been used in a variety of cosmetic applications as a source of nutrition and as a whitening agent. The flowers of Cassia fistula L, family Fabaceae, have been used as a traditional medicine for skin diseases and wound healing and have been reported to possess anti-oxidant properties. The anti-aging effect of C. Read More

    Curative effects of microneedle fractional radiofrequency system on skin laxity in Asian patients: A prospective, double-blind, randomized, controlled face-split study.
    J Cosmet Laser Ther 2017 Apr 1;19(2):83-88. Epub 2017 Feb 1.
    c University Hospital of Basel , Switzerland.
    Background: To date, no studies compared curative effects of thermal lesions in deep and superficial dermal layers in the same patient (face-split study).

    Objective: To evaluate skin laxity effects of microneedle fractional radiofrequency induced thermal lesions in different dermal layers.

    Methods And Materials: 13 patients underwent three sessions of a randomized face-split microneedle fractional radiofrequency system (MFRS) treatment of deep dermal and superficial dermal layer. Read More

    Patents on Therapeutic and Cosmetic Applications of Bioactives of Crocus Sativus L. and their Production through Synthetic Biology Methods: A Review.
    Recent Pat Biotechnol 2017 ;11(1):3-19
    CSIR-URDIP, Tapovan, S.No.113, 114, NCL Campus, Pashan, Pune 411008, Maharashtra. India.
    Background: Saffron (Crocus sativus L.) has a long history of use as a food additive and a traditional medicine for treating a number of disorders. Prominent bioactives of saffron are crocin, crocetin and safranal. Read More

    Filler migration to the forehead due to multiple filler injections in a patient addicted to cosmetic fillers.
    J Cosmet Laser Ther 2017 Apr 25;19(2):124-126. Epub 2017 Jan 25.
    a Department of Dermatology , Tri-Service General Hospital, National Defense Medical Center , Taipei , Taiwan.
    Filler migration is a potential complication following the injection of multiple fillers. With the increasing popularity of multiple filler injections, migrated granulomas should be an essential differential diagnosis for newly growing facial lumps. It is important for all physicians to be aware that complication induced by dermal fillers can occur in locations other than the planned injected sites. Read More

    A review on laser and light-based therapies for alopecia areata.
    J Cosmet Laser Ther 2017 Apr 25;19(2):93-99. Epub 2017 Jan 25.
    a Department of Dermatology and Cutaneous Surgery , University of Miami Miller School of Medicine , Miami , FL , USA.
    Alopecia areata is a form of non-scarring alopecia that results from a hyperactive immune response of T cells against hair follicles. Many patients with visible hair loss experience psychological and emotional distress, as a result of their cosmetic disfigurement, and frequently seek treatment. However, existing treatment methods, such as corticosteroids, topical irritants, sensitizing agents, immunosuppressants, and psoralen plus ultraviolet light A, may result in various adverse effects and often lack efficacy. Read More

    Blends and composites of exopolysaccharides; properties and applications: A review.
    Int J Biol Macromol 2017 Jan 3;94(Pt A):10-27. Epub 2016 Oct 3.
    Institute of Chemistry, Government College University, Faisalabad 38030, Pakistan. Electronic address:
    Exopolysaccharides are synthesized by bacteria and secreted into the external environment and they may be homopolymeric or heteropolymeric in configuration. They are believed to protect bacterial cells from heavy metals, desiccation or other environmental effect. EPS exhibit antitumor, anti-HIV, emulsion stabilization capacity, shear-thinning activity, suspension ability, high viscosities, excellent biocompatibility, high biodegradability and immunomodulatory properties. Read More

    Extracellular Metabolites from Industrial Microalgae and Their Biotechnological Potential.
    Mar Drugs 2016 Oct 20;14(10). Epub 2016 Oct 20.
    School of Food Science and Engineering, South China University of Technology, Wushan Rd. 381, Guangzhou 510641, China.
    Industrial microalgae, as a big family of promising producers of renewable biomass feedstock, have been commercially exploited for functional food, living feed and feed additives, high-value chemicals in nutraceuticals, cosmeceuticals, and chemical reagents. Recently, microalgae have also been considered as a group that might play an important role in biofuel development and environmental protection. Almost all current products of industrial microalgae are derived from their biomass; however, large amounts of spent cell-free media are available from mass cultivation that is mostly unexploited. Read More

    Polydeoxyribonucleotide improves wound healing of fractional laser resurfacing in rat model.
    J Cosmet Laser Ther 2017 Feb 2;19(1):43-48. Epub 2016 Dec 2.
    b Department of Dermatology , Seoul St. Mary's Hospital , Seoul , Republic of Korea.
    Background: Polydeoxyribonucleotide (PDRN) is an active compound that can promote wound healing. PDRN stimulates wound healing by enhancing angiogenesis and increasing fibroblast growth rates. Laser skin resurfacing is a popular cosmetic procedure for skin rejuvenation. Read More

    Development of Mushroom-Based Cosmeceutical Formulations with Anti-Inflammatory, Anti-Tyrosinase, Antioxidant, and Antibacterial Properties.
    Molecules 2016 Oct 14;21(10). Epub 2016 Oct 14.
    Mountain Research Centre (CIMO), ESA, Polytechnic Institute of Bragança, Campus de Santa Apolónia, 1172, 5300-253 Bragança, Portugal.
    The cosmetic industry is in a constant search for natural compounds or extracts with relevant bioactive properties, which became valuable ingredients to design cosmeceutical formulations. Mushrooms have been markedly studied in terms of nutritional value and medicinal properties. However, there is still slow progress in the biotechnological application of mushroom extracts in cosmetic formulations, either as antioxidants, anti-aging, antimicrobial, and anti-inflammatory agents or as hyperpigmentation correctors. Read More

    Jasmine rice panicle: A safe and efficient natural ingredient for skin aging treatments.
    J Ethnopharmacol 2016 Dec 6;193:607-616. Epub 2016 Oct 6.
    School of Cosmetic Science, Mae Fah Luang University, Chiang Rai, 57100 Thailand; Phytocosmetics and Cosmeceuticals Research Group, Mae Fah Luang University, Chiang Rai 57100, Thailand.
    Ethnopharmacological Relevance: While rice is one of the most important global staple food sources its extracts have found many uses as the bases of herbal remedies. Rice extracts contain high levels of phenolic compounds which are known to be bioactive, some of which show cutaneous benefits and activity towards skin disorders. This study highlights an assessment of the cellular activity and clinical efficacy of rice panicle extract, providing necessary information relevant to the development of new cosmetic products. Read More

    Utility of Ochrobactrum anthropi YC152 in a Microbial Fuel Cell as an Early Warning Device for Hexavalent Chromium Determination.
    Sensors (Basel) 2016 Aug 16;16(8). Epub 2016 Aug 16.
    Department of Biological Science and Technology, China University of Science and Technology, Taipei 11581, Taiwan.
    Fast hexavalent chromium (Cr(VI)) determination is important for environmental risk and health-related considerations. We used a microbial fuel cell-based biosensor inoculated with a facultatively anaerobic, Cr(VI)-reducing, and exoelectrogenic Ochrobactrum anthropi YC152 to determine the Cr(VI) concentration in water. The results indicated that O. Read More

    Micro-Needling Depth Penetration, Presence of Pigment Particles, and Fluorescein-Stained Platelets: Clinical Usage for Aesthetic Concerns.
    Aesthet Surg J 2017 Jan 16;37(1):71-83. Epub 2016 Aug 16.
    Dr Sasaki is a Clinical Professor, Loma Linda Medical University Center, Loma Linda, CA
    Background: Aesthetic micro-needling (MN) has demonstrated skin permeability to cosmeceutical ingredients and platelet-rich plasma by creating reversible micro-channels in the skin.

    Objectives: The purposes of this study were to determine: (1) actual needle depth-penetrations by adjusting needle lengths in a disposable tip of an electric MN device; (2) time-dependent passage of pigment and platelets; and (3) safety and efficacy profiles in patients.

    Methods: Excised micro-needled pre-auricular skin was used to determine actual depths of tissue penetration with six needle lengths, and the presence of massaged pigment particles (histological examination) and fluorescein-labeled platelets (confocal laser microscopy) in 1 mm depth micro-channels over an hour. Read More

    Skin aging and oxidative stress: Equol's anti-aging effects via biochemical and molecular mechanisms.
    Ageing Res Rev 2016 Nov 9;31:36-54. Epub 2016 Aug 9.
    Department of Physiology and Developmental Biology and The Neuroscience Center, Brigham Young University, Provo, UT 84602, USA. Electronic address:
    Oxygen in biology is essential for life. It comes at a cost during normal cellular function, where reactive oxygen species (ROS) are generated by oxidative metabolism. Human skin exposed to solar ultra-violet radiation (UVR) dramatically increases ROS production/oxidative stress. Read More

    Fifty years of research and development of cosmeceuticals: a contemporary review.
    J Cosmet Dermatol 2016 Dec 6;15(4):527-539. Epub 2016 Aug 6.
    Department of Dermatology, Frimley Park Hospital NHS Foundation Trust, Frimley, UK.
    Facial rejuvenation can be categorized into skincare and facial contouring. Research and development of cosmeceuticals is aimed at addressing the major signs of photoaging: wrinkles, dyschromia, and sallowness. Assessment of photoaging comes in clinical and photographic forms; a photonumeric scale developed by Griffiths et al. Read More

    Topical peptides as cosmeceuticals.
    Indian J Dermatol Venereol Leprol 2017 Jan-Feb;83(1):9-18
    Department of Dermatology, Goa Medical College, Bambolim, Goa, India.
    Peptides are known to have diverse biological roles, most prominently as signaling/regulatory molecules in a broad variety of physiological processes including defense, immunity, stress, growth, homeostasis and reproduction. These aspects have been used in the field of dermatology and cosmetology to produce short, stable and synthetic peptides for extracellular matrix synthesis, pigmentation, innate immunity and inflammation. The evolution of peptides over the century, which started with the discovery of penicillin, has now extended to their usage as cosmeceuticals in recent years. Read More

    (4R,6S)-2-Dihydromenisdaurilide is a Butenolide that Efficiently Inhibits Hepatitis C Virus Entry.
    Sci Rep 2016 Jul 18;6:29969. Epub 2016 Jul 18.
    Department of Microbiology and Immunology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
    Without a vaccine, hepatitis C virus (HCV) remains a significant threat, putting 170-300 million carriers worldwide at risk of cirrhosis and hepatocellular carcinoma. Although the direct-acting antivirals targeting HCV replication have revolutionized the treatment of hepatitis C, several obstacles persist, including resistance development, potential side-effects, and the prohibitive cost that limits their availability. Furthermore, treatment of HCV re-infection in liver transplantation remains a significant challenge. Read More

    Meeting the Challenges of Acne Treatment in Asian Patients: A Review of the Role of Dermocosmetics as Adjunctive Therapy.
    J Cutan Aesthet Surg 2016 Apr-Jun;9(2):85-92
    Dr SN Wong Skin, Hair, Nails and Laser Specialist Clinic, Mt Elizabeth Medical Centre, Singapore.
    Conventional acne treatment presents several challenges such as intolerable side effects and antibiotic resistance. Dermocosmetic products may be used to reduce these unwanted effects. Dermocosmetics include skin cleansers, topical sebum-controllers, skin antimicrobial/anti-inflammatory agents, moisturizers, sunscreens, and camouflage products. Read More

    Infraorbital Dark Circles: A Review of the Pathogenesis, Evaluation and Treatment.
    J Cutan Aesthet Surg 2016 Apr-Jun;9(2):65-72
    TOC Eye and Face, Austin, USA.
    Infraorbital dark circles represent a common and multifactorial challenge in the world of aesthetic medicine and are the result of a variety of factors including deep facial anatomy, soft tissue changes, as well as contributions from the skin. A variety of treatment options exist, and a customised management strategy can be developed for the particular anatomic changes present. A literature search using MEDLINE and non-MEDLINE sources was performed utilising keywords including: 'Dark circles' 'infraorbital dark circles', 'infraorbital pigment', 'under-eye circles' and 'lower eyelid bags'. Read More

    Topical Products for the Aging Face.
    Clin Plast Surg 2016 Jul 11;43(3):597-604. Epub 2016 May 11.
    Discovery Partners, LLC, 4913 Southern Hills Drive, Frisco, TX 75034, USA. Electronic address:
    This article focuses on nonprescription home-use topical treatment technologies for the aging face and is intended to serve as a guide for the core cosmeceutical technologies currently used and to help educate and assist the selection of topical antiaging products by the professional staff and their patients. Antiaging topical treatments for patient home use should be nonirritating, compatible with the patient skin type, effective, and complementary to surgical and minimally invasive office procedures, and aesthetically elegant. New topical antiaging technologies, formulated as monotherapy or as combinations with well-known cosmeceuticals, should present adequate clinical studies to support their selection for use. Read More

    Bioactive properties and potentials cosmeceutical applications of phlorotannins isolated from brown seaweeds: A review.
    J Photochem Photobiol B 2016 Sep 16;162:100-5. Epub 2016 Jun 16.
    Laboratory of Marine Bioresource Technology, Department of Marine Life Science, School of Marine Biomedical Sciences, Jeju National University, Jeju 690-756, Republic of Korea. Electronic address:
    Currently, natural ingredients are becoming more attractive for the industries such as functional food, nutraceuticals, cosmeceutical and pharmaceutical industries as people starting to believe naturally occurring compounds are safer to humans than artificial compounds. Seaweeds are one of the most interesting organisms found in oceans around the earth, which are carrying great ecological importance and contribute to increase the biodiversity of ecosystems where they were originated and habitat. Within last few decades, discovery of secondary metabolites with biological activities from seaweeds has been significantly increased. Read More

    Etiology and Management of Allergic Eyelid Dermatitis.
    Ophthal Plast Reconstr Surg 2016 Jun 20. Epub 2016 Jun 20.
    Department of Ophthalmology and Visual Sciences, Washington University in St. Louis. St. Louis, Missouri, U.S.A.
    Purpose: Allergic dermatitis is a common but often misdiagnosed condition that can present with a variety of findings including inflammation, eyelid malposition, and tearing. This study was performed to identify likely etiologies, along with presenting findings and treatment strategies for allergic dermatitis.

    Methods: A retrospective review of clinical records was performed of patients diagnosed with allergic dermatitis in academic oculoplastics practices from 2002 to 2014. Read More

    Current Perspective in the International Trade of Medicinal Plants Material: An Update.
    Curr Pharm Des 2016 ;22(27):4288-336
    University Institute of Pharmaceutical Sciences, Faculty of Pharmaceutical Sciences, Panjab University, Chandigarh-160014, India.
    Background: The recent years have seen an increased interest in medicinal plants together with the therapeutic use of phytochemicals. Medicinal plants are utilized by the industry for the production of extracts, phytopharmaceuticals, nutraceuticals and cosmeceuticals and their use is expected to grow faster than the conventional drugs. The enormous demand of medicinal plant material has resulted in huge trade both at domestic and international levels. Read More

    Enzymatic synthesis of bioactive compounds with high potential for cosmeceutical application.
    Appl Microbiol Biotechnol 2016 Aug 8;100(15):6519-43. Epub 2016 Jun 8.
    Department of Chemical Sciences, University of Naples "Federico II", Naples, Italy.
    Cosmeceuticals are cosmetic products containing biologically active ingredients purporting to offer a pharmaceutical therapeutic benefit. The active ingredients can be extracted and purified from natural sources (botanicals, herbal extracts, or animals) but can also be obtained biotechnologically by fermentation and cell cultures or by enzymatic synthesis and modification of natural compounds. A cosmeceutical ingredient should possess an attractive property such as anti-oxidant, anti-inflammatory, skin whitening, anti-aging, anti-wrinkling, or photoprotective activity, among others. Read More

    Current application of phytocompound-based nanocosmeceuticals for beauty and skin therapy.
    Int J Nanomedicine 2016 11;11:1987-2007. Epub 2016 May 11.
    Department of Applied Life Science, Nanotechnology Research Center, Chungju, Republic of Korea; Department of Biotechnology, College of Biomedical and Health Science, Konkuk University, Chungju, Republic of Korea.
    Phytocompounds have been used in cosmeceuticals for decades and have shown potential for beauty applications, including sunscreen, moisturizing and antiaging, and skin-based therapy. The major concerns in the usage of phyto-based cosmeceuticals are lower penetration and high compound instability of various cosmetic products for sustained and enhanced compound delivery to the beauty-based skin therapy. To overcome these disadvantages, nanosized delivery technologies are currently in use for sustained and enhanced delivery of phyto-derived bioactive compounds in cosmeceutical sectors and products. Read More

    Melasma and Post Inflammatory Hyperpigmentation: Management Update and Expert Opinion.
    Skin Therapy Lett 2016 Jan;21(1):1-7
    Spalding Drive Plastic Surgery and Cosmetic Dermatology, Beverly Hills, CA, USA.
    Dyschromia is a leading cause for cosmetic consultation, especially in those with diverse skin types (mixture of ethnicities) and with the rise of non-core and untrained physicians performing cosmetic procedures. Melasma and post-inflammatory hyperpigmentation (PIH) account for the majority of cases and are characterized by pigmented macules and patches distributed symmetrically in sun-exposed areas of the forehead, cheeks, and chin in melasma, and irregularly in areas of inflammation or an inciting traumatic event with PIH. Treatment is challenging and focused on a variety of mechanisms to stop, hinder, and/or prevent steps in the pigment production (melanocytic hyperactivity) process, breaking down deposited pigment for internal removal or external release, exfoliating cells to enhance turnover, and decreasing inflammation. Read More

    Laser-Assisted Drug Delivery.
    Dermatol Surg 2016 Aug;42(8):919-31
    *Department of Dermatology, Naval Medical Center San Diego, San Diego, California; †Cosmetic Laser Dermatology, San Diego, California.
    Background: Laser-assisted drug delivery (LADD) is an evolving new therapy with many possible applications as a highly targeted customizable method for distribution of drugs within the skin. LADD offers the advantages of accessibility, noninvasiveness, compliance, safety, and effectiveness.

    Objective: To review the available literature regarding LADD. Read More

    Super-cooled and amorphous lipid-based colloidal dispersions for the delivery of phytosterols.
    Soft Matter 2016 Jul;12(27):5835-46
    Unilever R&D Vlaardingen, Olivier van Noortlaan 120, 3133 AT Vlaardingen, The Netherlands. and Soft Condensed Matter, Debye Institute for Nanomaterials Science, Utrecht University, Princetonplein 5, 3584 CC Utrecht, The Netherlands.
    Super-cooled and amorphous lipid-based colloids are highly desirable delivery systems because of their ability to encapsulate compounds in a soluble or in a non-crystalline state. In this study, we demonstrate the preparation and characterization of super-cooled and amorphous lipid-based nanoscale colloidal dispersions containing high concentrations of phytosterols (PSs). PSs are highly hydrophobic natural bioactive compounds that are known to significantly reduce blood cholesterol levels in humans, but are insoluble in water and are poorly soluble in common lipids such as triacylglycerols (TAGs). Read More

    Cosmeceuticals: peptides, proteins, and growth factors.
    J Cosmet Dermatol 2016 Dec 3;15(4):514-519. Epub 2016 May 3.
    Faculty of Health Sciences, University of Granada, Granada, Spain.
    Recent research advances in the molecular and biochemical processes involved in wound healing and skin aging have led to the development of innovative cosmeceuticals that rely on peptides, proteins, and growth factors to enhance skin health. Although the long-term benefits of these products have not been fully tested and evaluated, evidence of the benefits derived from their use is steadily growing. This study describes the peptides, proteins, and growth factors that are most frequently used in cosmeceuticals and discusses their potential benefits and practical use in dermatology. Read More

    Polysaccharides from the Marine Environment with Pharmacological, Cosmeceutical and Nutraceutical Potential.
    Molecules 2016 Apr 27;21(5). Epub 2016 Apr 27.
    Department of Biology and Evolution of Marine Organisms, Stazione Zoologica Anton Dohrn, Villa Comunale, 80121 Napoli, Italy.
    Carbohydrates, also called saccharides, are molecules composed of carbon, hydrogen, and oxygen. They are the most abundant biomolecules and essential components of many natural products and have attracted the attention of researchers because of their numerous human health benefits. Among carbohydrates the polysaccharides represent some of the most abundant bioactive substances in marine organisms. Read More

    Combination Therapy in Midfacial Rejuvenation.
    Dermatol Surg 2016 May;42 Suppl 2:S83-8
    *Department of Dermatology and Skin Science, University of British Columbia, Vancouver, Canada; †Department Medicine, University of California, Los Angeles (UCLA), Los Angeles, California.
    Background: Facial aging in the midface reflects cumulative results of multiple intrinsic and extrinsic factors over time. Midfacial rejuvenation procedures can make a positive impact on facial attractiveness and patient satisfaction.

    Objective: To review evidence and clinical experience using combination treatments for midfacial rejuvenation to achieve optimal outcomes. Read More

    Usefulness of liquid-crystal oral formulations to enhance the bioavailability and skin tissue targeting of p-amino benzoic acid as a model compound.
    Eur J Pharm Sci 2016 Jun 9;88:282-90. Epub 2016 Apr 9.
    Faculty of Pharmaceutical Sciences, Josai University, 1-1 Keyakidai, Sakado, Saitama 350-0295, Japan. Electronic address:
    Topical formulations are not always suitable to deliver active ingredients to large areas of skin. Thus, in this study, we aimed to develop an oral formulation for skin tissue targeting with a high bioavailability using liquid crystal (LC) dispersions comprising cubosomes of a mal-absorptive model compound, p-amino benzoic acid (PABA), which is an active element in cosmeceuticals, dietary supplements and skin disorder medicines. The bioavailability and skin concentration of PABA were investigated after oral administration in rats. Read More

    An Approach to Cosmeceuticals.
    J Drugs Dermatol 2016 Apr;15(4):452-6
    The cosmeceutical industry is a multi-billion dollar, consumer-driven market. Products promise highly desirable anti-aging benefits, but are not subject to regulation. We present an introduction to cosmeceuticals for the general and cosmetic dermatologist, including definitions and explanations of key terms, an approach to the evidence base, a dissection of chamomile and green tea, two paradigmatic cosmeceutical products, and a window into the underlying psychology of this vast marketplace. Read More

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