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Crit Rev Food Sci Nutr 2022 Jun 16:1-20. Epub 2022 Jun 16.

Pharmacognosy Department, College of Pharmacy, Cairo University, Cairo, Egypt.

Phenylpropenes represent a major subclass of plant volatiles, including eugenol, and ()-anethole. They contribute to the flavor and aroma of many chief herbs and spices, to exert distinct notes in food, , spicy anise- and clove-like to fruit. Asides from their culinary use, they appear to exert general health effects, whereas some effects are specific, e. Read More

Int J Med Mushrooms 2022 ;24(4):1-13

CEFE, Univ Montpellier, CNRS, EPHE, IRD, Laboratory of Botany, Phytochemistry and Mycology, Faculty of Pharmacy, Montpellier Cedex, France.

Macrofungi (mushrooms) have been studied for their nutritional value and medicinal properties. However, progress in the biotechnological application of macrofungi in the cosmetic industry as cosmeceuticals and nutricosmetics remains slow. Currently, the cosmetic industry is in a constant search for valuable natural ingredients or extracts with relevant bioactive properties (e. Read More

SAGE Open Med Case Rep 2022 7;10:2050313X221102489. Epub 2022 Jun 7.

Division of Dermatology, Department of Medicine, University of Calgary, AB, Canada.

Background: Microneedling is a common non-invasive procedure used for a variety of dermatologic conditions. It is associated with a low rate of adverse events which are typically temporary. Hypersensitivity reactions, including granuloma formation, are a rare adverse event, with only 10 cases previously reported. Read More

Molecules 2022 May 30;27(11). Epub 2022 May 30.

School of Engineering and Sciences, Tecnológico de Monterrey, Monterrey 64849, Mexico.

Microalgae are complex photosynthetic organisms found in marine and freshwater environments that produce valuable metabolites. Microalgae-derived metabolites have gained remarkable attention in different industrial biotechnological processes and pharmaceutical and cosmetic industries due to their multiple properties, including antioxidant, anti-aging, anti-cancer, phycoimmunomodulatory, anti-inflammatory, and antimicrobial activities. These properties are recognized as promising components for state-of-the-art cosmetics and cosmeceutical formulations. Read More

Plants (Basel) 2022 May 31;11(11). Epub 2022 May 31.

Center for Research and Technology of Agro-Environmental and Biological Sciences (CITAB-UTAD), University of Trás-os-Montes e Alto Douro (UTAD), Quinta de Prados, 5001-801 Vila Real, Portugal.

Labdanum resin from L. (Cistaceae) is an abundant natural resource in the Iberian Peninsula worth being explored in a sustainable manner. It is already used in the cosmetic industry; mainly by the fragrances/perfumery sector. Read More

Molecules 2022 May 21;27(10). Epub 2022 May 21.

Department of Pharmaceutical Science, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.

In this research, we aimed to compare the biological activities related to cosmeceutical applications of glutinous rice husk extracted by aqueous enzymatic extraction (AEE) and conventional solvent extraction. Cellulase enzymes were used to assist the extraction process. The vanillic and ferulic acid contents of each extract were investigated by high-performance liquid chromatography, and their antioxidant and anti-aging activities were investigated by spectrophotometric methods. Read More

Molecules 2022 May 19;27(10). Epub 2022 May 19.

Department of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.

This study aimed to investigate the chemical composition and reveal the selective inhibitory activity of (L.) Willd. essential oil (AGO) on acetylcholinesterase (AChE) compared to butyrylcholinesterase (BChE). Read More

Foods 2022 May 23;11(10). Epub 2022 May 23.

Unidad de Investigación en Nutrición, Salud, Alimentos Funcionales y Nutraceúticos, Universidad San Ignacio de Loyola (UNUSAN-USIL), Av. La Fontana 750, Lima 15024, Peru.

The sinami palm ( H. Karst) is a plant from the South American Amazonia that has great potential for industrial applications in the development of functional foods, nutraceuticals and cosmeceuticals. In this manuscript, the physicochemical properties, total polyphenol content and antioxidant activity of sinami oil that was obtained using four extraction systems, namely expeller press extraction (EPE), cold press extraction (CPE), ultrasound-assisted extraction (UAE) and supercritical fluid extraction (SFE), were studied and compared. Read More

Sci Rep 2022 05 10;12(1):7683. Epub 2022 May 10.

Department of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University, Chiang Mai, 50200, Thailand.

The aims of this study were to evaluate the biological activities of black Dimocarpus longan Lour. seed extracts and develop a lamellar liquid crystal (LLC). Different solvents, including petroleum ether, ethyl acetate, and 95% v/v ethanol, were used in the maceration of black D. Read More

Front Pharmacol 2022 20;13:851242. Epub 2022 Apr 20.

Innovation Center for Holistic Health, Nutraceuticals, and Cosmeceuticals, Faculty of Pharmacy, Chiang Mai University, Chiang Mai, Thailand.

Breast cancer is the most common invasive cancer in women and the second leading cause of cancer death in women after lung cancer. The purpose of this study is a targeted delivery toward (on MCF7 and 4T1 breast cancer cell lines) through niosomes-based nanocarriers. To this end, different bioactive molecules, including hyaluronic acid (HA), folic acid (FA), and polyethylene glycol (PEG), were used and compared for surface modification of niosomes to enhance endocytosis. Read More

Clin Hemorheol Microcirc 2022 Apr 16. Epub 2022 Apr 16.

Institute of Biotechnology, Molecular Cell Biology, Brandenburg University of Technology, Senftenberg, Germany.

Aim: To examine to what extent the high frame rate contrast-enhanced ultrasound (HiFR) diagnostic enables the conclusive diagnosis of liver changes with suspected malignancy.

Material/methods: Ultrasound examinations were performed by an experienced examiner using a multifrequency probe (SC6-1) on a high-end ultrasound system (Resona 7, Mindray) to clarify liver changes that were unclear on the B-scan. A bolus of 1-2. Read More

Antioxidants (Basel) 2022 Apr 18;11(4). Epub 2022 Apr 18.

Department of Crop Science, Konkuk University, Seoul 05029, Korea.

Natural carotenoids (CARs), viz. β-carotene, lutein, astaxanthin, bixin, norbixin, capsanthin, lycopene, canthaxanthin, β-Apo-8-carotenal, zeaxanthin, and β-apo-8-carotenal-ester, are being studied as potential candidates in fields such as food, feed, nutraceuticals, and cosmeceuticals. CAR research is advancing in the following three major fields: (1) CAR production from natural sources and optimization of its downstream processing; (2) encapsulation for enhanced physical and chemical properties; and (3) preclinical, clinical, and epidemiological studies of CARs' health benefits. Read More

Antioxidants (Basel) 2022 Mar 30;11(4). Epub 2022 Mar 30.

Centro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal.

The cosmetic industry is constantly searching for bioactive ingredients, namely, those obtained from natural sources with environmentally friendly connotations and less toxic effects. A previous study of our research group optimized the extraction of phenolic compounds from by heat-assisted extraction. Due to its richness in different phenolic compounds, the present work aimed to develop a formulation containing leaf extract. Read More

J Agric Food Chem 2022 Apr 14;70(16):4981-4994. Epub 2022 Apr 14.

Institute of Microbial Pharmaceuticals, College of Life and Health Sciences, Northeastern University, Shenyang 110819, P. R. China.

Blue gum () is a widely used botanical in the cosmeceutical and food industries. Although blue gum leaves are known for abundant essential oils, their nonvolatile phytochemical constituents and bioactivities remain unclear. Herein, a phytochemical investigation of blue gum leaves led to the identification of eight new monoterpene acid and gallic acid glucose esters ( and ; glubosides A-H, respectively) and 12 known analogues ( and ). Read More

Int J Environ Res Public Health 2022 03 29;19(7). Epub 2022 Mar 29.

Department of Drug Technology and Social Pharmacy, Lithuanian University of Health Sciences, LT-50162 Kaunas, Lithuania.

The documentation of ethnopharmaceutical knowledge has always been important for the preservation of countries' cultural, social, and economic identity. The COVID-19 pandemic with the collapse of healthcare, which has left the individual health to self-care, has also forced us to look back at ethnopharmacology from a practical point of view. This is the first study in Lithuania, dedicated entirely to ethnopharmaceuticals used for skin diseases and cosmetics, and the first study to analyse ethnopharmacology as a Lithuanian phenomenon during the ongoing COVID-19 pandemic. Read More

J Ethnopharmacol 2022 Jul 9;293:115274. Epub 2022 Apr 9.

Analytical Chemistry Department, CSIR-Central Institute of Medicinal and Aromatic Plants, Lucknow, 226015, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India. Electronic address:

Ethnopharmacological Relevance: Duranta erecta Linn. belonging to the Verbenaceae family is widely used in the traditional systems of medicines practiced in Bangladesh, India, Nigeria, the Philippines, and Brazil. The ethnomedicinal application as vermifuge, febrifuge, diuretic, anti-parasitic, and anti-malarial are well documented. Read More

Oxid Med Cell Longev 2022 28;2022:3486257. Epub 2022 Mar 28.

AgroBioSciences, Mohammed VI Polytechnic University, Lot 660, Hay Moulay Rachid, Ben Guerir 43150, Morocco.

We previously annotated the phytochemical constituents of a root extract from var. and highlighted its hepatoprotective and hypoglycemic properties. We here extended our study on the leaf extract and identified its phytoconstituents using HPLC-PDA-ESI-MS/MS. Read More

Biomed Res Int 2022 17;2022:1725053. Epub 2022 Mar 17.

Department of Pharmaceutics, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, 63100 Punjab, Pakistan.

Objective: Multiple emulsions have the ability to incorporate both lipophilic and hydrophilic actives in the same preparation and facilitate permeation of active ingredients through skin. The current study was aimed at formulating niacinamide/ferulic acid-loaded stable multiple emulsion (MNF) and its / characterization as a cosmeceutical product.

Methods: Both the compounds were evaluated for their radical scavenging potential by the DPPH method and FTIR analysis. Read More

Exp Dermatol 2022 05 31;31(5):674-688. Epub 2022 Mar 31.

Esco Aster Pte Ltd, Singapore, Singapore.

Skin ageing is predominantly caused by either intrinsic or extrinsic factors, leading to undesirable skin features. Advancements in both molecular and cellular fields have created possibilities in developing novel stem cell-derived active ingredients for cosmeceutical applications and the beauty industry. Mesenchymal stromal cell (MSC)-derived secretomes or conditioned media hold great promise for advancing skin repair and regeneration due to the presence of varying cytokines. Read More

Molecules 2022 Mar 18;27(6). Epub 2022 Mar 18.

Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Hat Yai 90112, Songkhla, Thailand.

This study investigated the antioxidant, antimicrobial, anticancer, and phytochemical profiling of extracts from the leaves and stem/root of (AE). The total phenolic content (TPC), total flavonoid content (TFC), 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH) radical-scavenging activity, 2, 2'-azino-Bis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS) radical-scavenging activity, metal chelating activities (MCA), ferric reducing antioxidant power (FRAP) and oxygen radical antioxidant capacity (ORAC) were used for antioxidant assessment. The ethanolic extracts of the leaves (AEL-nor) and stem/root (AEWP-nor) without chlorophyll removal and those with chlorophyll removal, using sedimentation process (AEL-sed and AEWP-sed), were prepared. Read More

Gels 2022 Mar 10;8(3). Epub 2022 Mar 10.

Nanotechnology Lab, School of Pharmaceutics Education and Research (SPER), Jamia Hamdard University, New Delhi 110062, Delhi, India.

Nanotechnology has the potential to generate advancements and innovations in formulations and delivery systems. This fast-developing technology has been widely exploited for diagnostic and therapeutic purposes. Today, cosmetic formulations incorporating nanotechnology are a relatively new yet very promising and highly researched area. Read More

Curr Pharm Des 2022 Mar 21. Epub 2022 Mar 21.

Department of Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal 576104, Karnataka, India.

Nanotechnology is an innovative area of science that deals with things smaller than 100 nanometers. The influence of nanotechnology in the cosmetic industry is overwhelming since it can enhance the properties attained by the particles at the nano level which includes color, solubility, etc, and also promotes the bioavailability of API. A plethora of nanomaterials can be employed in cosmetics including organic and inorganic nanoparticles. Read More

J Cosmet Laser Ther 2022 Mar 15:1-2. Epub 2022 Mar 15.

Department of Dermatology, University of Minnesota, Minneapolis, MN, USA.

Objectives: The topical application of a combination Vitamin C, Vitamin E, and Ferulic acid serum following ablative fractional resurfacing has been reported to shorten post-procedure downtime and improve wound healing. However, transcutaneous drug delivery of cosmeceuticals initially meant for topical application have also been shown to have unintended side effects. The objective of our study was to report safety data from our single academic center experience consisting of patients treated with topical application of a vitamin C-containing cosmeceutical immediately following fractional ablative CO laser treatment with a focus on reportable side effects. Read More

J Oleo Sci 2022 Apr 14;71(4):481-491. Epub 2022 Mar 14.

Department of Biotechnology, Kumaun University, Bhimtal Campus.

The study aims to identify the fatty acid composition in Prinsepia utilis seeds collected from diverse populations of Western Himalaya, India. The seeds contained higher saturated fatty acid (SFA-43.09%; Average of all populations) followed by polyunsaturated fatty acid (PUFA - 29. Read More

Int J Mol Sci 2022 Mar 7;23(5). Epub 2022 Mar 7.

Biofunctional Molecule Exploratory Research Group, School of Pharmacy, Monash University Malaysia, Bandar Sunway 47500, Malaysia.

Sunlight is an important factor in regulating the central circadian rhythm, including the modulation of our sleep/wake cycles. Sunlight had also been discovered to have a prominent influence on our skin's circadian rhythm. Overexposure or prolonged exposure to the sun can cause skin photodamage, such as the formation of irregular pigmentation, collagen degradation, DNA damage, and even skin cancer. Read More

Foods 2022 Mar 6;11(5). Epub 2022 Mar 6.

Innovation Center for Holistic Health, Nutraceuticals, and Cosmeceuticals, Chiang Mai University, Chiang Mai 50200, Thailand.

Urbanization influences our lifestyle, especially in fast-paced environments where we are more prone to stress. Stress management is considered advantageous in terms of longevity. The use of probiotics for psychological treatment has a small amount of diverse proven evidence to support this. Read More

J Biosci Bioeng 2022 Jun 4;133(6):547-554. Epub 2022 Mar 4.

Engineering Research Center of Natural Cosmeceuticals College of Fujian Province, Xiamen Medical College, Xiamen 361023, Fujian, China; Department of Public Health and Medical Technology, Xiamen Medical College, Xiamen 361023, Fujian, China; Institute of Respiratory Diseases Xiamen Medical College, Xiamen Medical College, Xiamen 361023, Fujian, China. Electronic address:

Tibetan kefir grain as the starter of milk fermentation has been applied as functional food with many bioactive characteristics. In this study, the milk whey product (TKG-MW) was obtained through the milk fermentation of Tibetan kefir grain containing the dominant Lactobacillus, Acetobacter, and Bacillus after 3 and 6 days of cultivation. Antioxidant, anti-inflammatory, and melanogenesis inhibition capacities under TKG-MW treatment were analyzed. Read More

Saudi Pharm J 2022 Jan 31;30(1):53-65. Epub 2021 Dec 31.

Department of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.

Cosmeceuticals are a branch of cosmetic products that forms a bridge between cosmetic and drug products. It is a fast-growing branch of the cosmetic industry, especially after the introduction of novel formulation and manufacturing techniques such as lipid nanoparticles (LNPs). These LNPs-based cosmeceutical products offer several advantages such as enhanced bioavailability of cosmeceutical active ingredients (CAIs), improved aesthetic appeal, and stability of the final products. Read More

Molecules 2022 Feb 13;27(4). Epub 2022 Feb 13.

UB-CARE S.r.l.-Spin-Off University of Pavia, 27100 Pavia, Italy.

(1) Background: Acne is a widespread skin disease, especially among adolescents. Following the COVID-19 pandemic and the use of masks, the problem has been affecting a greater number of people, and the attention of the skin care beauty routine cosmetics has been focused on the "Maskne", caused by the sebum excretion rate (SER) that stimulates microbial proliferation. (2) Methods: the present study was focused on the rheological characterization and quality assurance of the preservative system of an anti-acne serum. Read More

J Fungi (Basel) 2022 Jan 29;8(2). Epub 2022 Jan 29.

Department of Life Sciences, National University of Kaohsiung, Kaohsiung 811, Taiwan.

For thousands of years, fungi or mushrooms have been used as biological control agents, cosmeceuticals, dietary foods and supplements, pharmaceuticals, and traditional medicines around the world [... Read More