508 results match your criteria Cosmeceuticals


Bioactive Pigments from Isolated Bacteria and Its Antibacterial, Antioxidant and Sun Protective Application Useful for Cosmetic Products.

Indian J Microbiol 2020 Sep 15;60(3):379-382. Epub 2020 Apr 15.

B. V. Patel Pharmaceutical Education and Research Development (PERD) Centre, Ahmedabad, Gujarat India.

Bacterial pigments are the unique and sustainable source of bioactive colour compounds used in cosmetics, food, textiles, printing and pharmaceutical products. Here, we report the pigment-producing isolates and their biological activities that could be benefited for different industries including cosmeceuticals. In this study, a total of 19 pigment-producing bacteria were isolated and purified from collected soil and water samples. Read More

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http://dx.doi.org/10.1007/s12088-020-00870-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329960PMC
September 2020

Cosmeceutical awareness among community pharmacists in Jeddah, Saudi Arabia: The case of sunscreens and moisturizers.

J Cosmet Dermatol 2020 Jun 23. Epub 2020 Jun 23.

Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia.

Background: Although cosmetic products such as sunscreens and moisturizers are generally considered safe, they can be less effective or harmful if used improperly. Thus, pharmacist's awareness about cosmeceuticals is pivotal in counseling about the ingredients and the proper use of such products.

Objective: To evaluate the awareness level of community pharmacists regarding cosmetic products particularly sunscreens and moisturizers in Jeddah, Saudi Arabia. Read More

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http://dx.doi.org/10.1111/jocd.13536DOI Listing

Algae Metabolites in Cosmeceutical: An Overview of Current Applications and Challenges.

Mar Drugs 2020 Jun 19;18(6). Epub 2020 Jun 19.

Department of Biological Sciences, School of Science & Technology, Sunway University, Bandar Sunway 47500, Selangor Darul Ehsan, Malaysia.

Cosmetics are widely used by people around the world to protect the skin from external stimuli. Consumer preference towards natural cosmetic products has increased as the synthetic cosmetic products caused adverse side effects and resulted in low absorption rate due to the chemicals' larger molecular size. The cosmetic industry uses the term "cosmeceutical", referring to a cosmetic product that is claimed to have medicinal or drug-like benefits. Read More

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http://dx.doi.org/10.3390/md18060323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344841PMC

COVID-19 and the endothelium.

Clin Hemorheol Microcirc 2020 Jun 19. Epub 2020 Jun 19.

Institute of Biotechnology, Molecular Cell Biology, Brandenburg University of Technology Cottbus-Senftenberg, Germany.

There is growing evidence that COVID-19 not only affects the lungs but beyond that the endothelial system. Recent studies showed that this can lead to microcirculatory impairments and in consequence to functional disorders of all inner organs. The combination of endothelial dysfunction with a generalized inflammatory state and complement elements may together contribute to the overall pro-coagulative state described in COVID-19 patients leading to venular as well as to arteriolar occlusions. Read More

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http://dx.doi.org/10.3233/CH-209007DOI Listing

Formulation and efficacy evaluation of the safe and efficient moisturizing snow mushroom hand sanitizer.

J Cosmet Dermatol 2020 Jun 12. Epub 2020 Jun 12.

School of Cosmetic Science, Mae Fah Luang University, Chiang Rai, Thailand.

Objectives: Snow fungus or snow mushroom or white jelly mushroom (Tremella fuciformis), the edible mushroom, was formulated into hand sanitizer in form of moisturizing alcohol-based hand rub (ABHR) gel.

Methods: The stable base ABHRs were developed. The preferred bases were incorporated with various concentrations of snow mushroom extract. Read More

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http://dx.doi.org/10.1111/jocd.13543DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323351PMC

Valorization of Mushroom By-Products as a Source of Value-Added Compounds and Potential Applications.

Molecules 2020 Jun 9;25(11). Epub 2020 Jun 9.

CBQF-Centro de Biotecnologia e Química Fina-Laboratório Associado, Escola Superior de Biotecnologia, Universidade Católica Portuguesa, Rua Diogo Botelho 1327, 4169-005 Porto, Portugal.

Nowadays, the food sector is highly concerned with environmental issues and foreseen to develop strategies to reduce waste and losses resulting from activities developed in the food system. An approach is to increment added value to the agro-industrial wastes, which might provide economic growth and environmental protection, contributing to a circular economy. Mushroom by-products represent a disposal problem, but they are also promising sources of important compounds, which may be used due to their functional and nutritional properties. Read More

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http://dx.doi.org/10.3390/molecules25112672DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321189PMC

Traditional fermented foods with anti-aging effect: A concentric review.

Food Res Int 2020 Aug 23;134:109269. Epub 2020 Apr 23.

Research Institute of Biotechnology and Medical Converged Science, Dongguk University-Seoul, Goyangsi, South Korea. Electronic address:

Fermentation has been applied since antiquity as a way to preserve foodstuff or as a necessary step in the production of a variety of products. The research was initially focused on accurate description of production procedure and identification of parameters that may affect the composition and dynamics of the developing micro-communities, since the major aim was standardization and commercial exploitation of the products. Soon it was realized that consumption of these products was associated with an array of health benefits, such as anti-hypertensive, anti-inflammatory, anti-diabetic, anti-carcinogenic and anti-allergenic activities. Read More

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http://dx.doi.org/10.1016/j.foodres.2020.109269DOI Listing

Impact of Multivalence and Self-Assembly in the Design of Polymeric Antimicrobial Peptide Mimics.

ACS Appl Mater Interfaces 2020 Jul 25;12(27):30052-30065. Epub 2020 Jun 25.

Institute of Chemistry, University of Potsdam, Karl-Liebknecht-Straße 24-25, 14476 Potsdam, Germany.

Antimicrobial resistance is an increasingly serious challenge for public health and could result in dramatic negative consequences for the health care sector during the next decades. To solve this problem, antibacterial materials that are unsusceptible toward the development of bacterial resistance are a promising branch of research. In this work, a new type of polymeric antimicrobial peptide mimic featuring a bottlebrush architecture is developed, using a combination of reversible addition-fragmentation chain transfer (RAFT) polymerization and ring-opening metathesis polymerization (ROMP). Read More

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http://dx.doi.org/10.1021/acsami.0c05944DOI Listing

The influence of probiotics on bile acids in diseases and aging.

Biomed Pharmacother 2020 Aug 3;128:110310. Epub 2020 Jun 3.

Innovation Center for Holistic Health, Nutraceuticals, and Cosmeceuticals, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand. Electronic address:

Recent evidence indicates the use of probiotics in the prevention and treatment of diseases. Probiotics are capable of changing the gut microbiota composition and bile acid synthesis to elicit health benefits such as cholesterol-lowering, weight reduction, and improving insulin sensitivity. The aging population is prone to develop diseases because of their decreased physiological and biological systems. Read More

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http://dx.doi.org/10.1016/j.biopha.2020.110310DOI Listing

Marine-Derived Compounds with Potential Use as Cosmeceuticals and Nutricosmetics.

Molecules 2020 May 29;25(11). Epub 2020 May 29.

Laboratório de Química Orgânica e Farmacêutica, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, Rua de Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal.

The cosmetic industry is among the fastest growing industries in the last decade. As the beauty concepts have been revolutionized, many terms have been coined to accompany the innovation of this industry, since the beauty products are not just confined to those that are applied to protect and enhance the appearance of the human body. Consequently, the terms such as cosmeceuticals and nutricosmetics have emerged to give a notion of the health benefits of the products that create the beauty from inside to outside. Read More

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http://dx.doi.org/10.3390/molecules25112536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7321322PMC

The Influence of Supplementation of Anthocyanins on Obesity-Associated Comorbidities: A Concise Review.

Foods 2020 May 26;9(6). Epub 2020 May 26.

Innovation Center for Holistic Health, Nutraceuticals, and Cosmeceuticals, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.

Anthocyanins are water-soluble plant pigments, and based on their chemical structure (nature, position, and the number of sugar moieties attached; the number of hydroxyl groups; acylation of sugars with acids) about 635 different anthocyanins have been identified and reported from plants. Cyanidin, peonidin, pelargonidin, petunidin, and malvidin are the commonly found anthocyanidins (aglycon forms of anthocyanins) in edible plants out of almost 25 anthocyanidins that are identified (based on the position of methoxyl and hydroxyl groups in the rings) in nature. Anthocyanins are known for numerous health benefits including anti-diabetes, anti-obesity, anti-inflammatory bowel disease, anti-cancer, etc. Read More

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http://dx.doi.org/10.3390/foods9060687DOI Listing

Agriculture waste valorisation as a source of antioxidant phenolic compounds within a circular and sustainable bioeconomy.

Food Funct 2020 Jun;11(6):4853-4877

Nutrition and Bromatology Group, Analytical and Food Chemistry Department, Faculty of Food Science and Technology, University of Vigo, Ourense Campus, E-32004 Ourense, Spain.

Planet globalization, population growth and its consequent need to produce large amounts of food, or individual economic benefits and the prioritization of this over environment health, are factors that that have contributed to the development, in some cases, of a linear-producing modern agricultural system. In contrast to traditional and local agriculture, which was based on circular sustainability models, modern agriculture currently produces tons of waste that is accumulated in landfill, creating controversial consequences, instead of being reintroduced into the production chain with a novel purpose. However, these residues from agriculture are rich in bioactive compounds, including phenolic compounds, secondary metabolites that are found naturally in plants, which show antioxidant, anti-inflammatory, cardioprotective and anticancer capacities, among others. Read More

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http://dx.doi.org/10.1039/d0fo00937gDOI Listing

Enhanced Transdermal Delivery of Concentrated Capsaicin from Chili Extract-Loaded Lipid Nanoparticles with Reduced Skin Irritation.

Pharmaceutics 2020 May 19;12(5). Epub 2020 May 19.

Department of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.

The aim of this study was to develop lipid-based nanoparticles that entrapped a high concentration of capsaicin (0.25%) from a capsicum oleoresin extract. The solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) were strategically fabricated to entrap capsaicin without a hazardous solvent. Read More

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http://dx.doi.org/10.3390/pharmaceutics12050463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285225PMC

Water Extract from Inflorescences of Industrial Hemp Futura 75 Variety as a Source of Anti-Inflammatory, Anti-Proliferative and Antimycotic Agents: Results from In Silico, In Vitro and Ex Vivo Studies.

Antioxidants (Basel) 2020 May 17;9(5). Epub 2020 May 17.

Department of Pharmacy, University "G. d'Annunzio" of Chieti-Pescara, 66100 Chieti, Italy.

Industrial hemp () is traditionally cultivated as a valuable source of fibers and nutrients. Multiple studies also demonstrated antimicrobial, anti-proliferative, phytotoxic and insecticide effects of the essential oil from hemp female inflorescences. On the other side, only a few studies explored the potential pharmacological application of polar extracts from inflorescences. Read More

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http://dx.doi.org/10.3390/antiox9050437DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278775PMC

Phenolic-rich Pomegranate Peel Extract: In Vitro, Cellular, and In Vivo Activities for Skin Hyperpigmentation Treatment.

Planta Med 2020 May 19. Epub 2020 May 19.

School of Cosmetic Science, Mae Fah Luang University, Chiang Rai, Thailand.

The pomegranate phenolics are reported to have cutaneous benefits and to be effective in treating skin disorders, including hyperpigmentation. In this context, a preparation method was developed by which to obtain phenolic-rich pomegranate peel extract. Sinapic acid was presented as the major pomegranate peel phenolics, followed by gallic and ellagic acids, and 4 additional phenolics. Read More

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http://dx.doi.org/10.1055/a-1170-7785DOI Listing

A Clinical Anti-Ageing Comparative Study of 0.3 and 0.5% Retinol Serums: A Clinically Controlled Trial.

Skin Pharmacol Physiol 2020 19;33(2):102-116. Epub 2020 May 19.

Department of Cosmetology and Aesthetic Dermatology, Faculty of Pharmacy, Medical University of Lodz, Lodz, Poland.

Background: Retinol influences the process of keratinization of the epidermis, which improves stratum corneum structure and reduces transepidermal water loss. It also significantly enhances mature skin by brightening hyperpigmentation and reducing the signs of photoageing. Cosmeceuticals are intended to both provide aesthetic effects for the skin and allow dermatological treatment. Read More

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http://dx.doi.org/10.1159/000508168DOI Listing

Optimization of L. Kernel Extract-Loaded Nanoemulsions via Response Surface Methodology, Characterization, Stability, and Skin Permeation for Anti-Acne Cosmeceutical Application.

Pharmaceutics 2020 May 14;12(5). Epub 2020 May 14.

Department of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.

This study aimed to optimize nanoemulsions loading with L. kernel extract using response surface methodology for enhancing the stability and skin permeation of the extract. Central composite design was employed for optimization and evaluation of three influencing factors including hydrophile-lipophile balance (HLB), % co-surfactant (PEG-7 glyceryl cocoate), and surfactant-to-oil ratio (SOR) on physical properties of the nanoemulsions. Read More

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http://dx.doi.org/10.3390/pharmaceutics12050454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285188PMC

Protective effects of a comprehensive topical antioxidant against ozone-induced damage in a reconstructed human skin model.

Arch Dermatol Res 2020 May 8. Epub 2020 May 8.

skinbetter science, LLC, 3200 E Camelback Rd, Suite 395, Phoenix, AZ, USA.

Tropospheric ozone (O) is a source of oxidative stress. This study examined the ability of a topical antioxidant (WEL-DS) to inhibit O-mediated damage in a human epidermal skin model. Four groups of tissues (N = 24) were compared: Group 1 (control) were untreated and unexposed; Group 2 were untreated and exposed to O (0. Read More

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http://dx.doi.org/10.1007/s00403-020-02083-0DOI Listing

Comparative physicochemical stability and clinical anti-wrinkle efficacy of transdermal emulgel preparations of 5% sodium ascorbyl phosphate and or ascorbic acid on human volunteers.

J Cosmet Dermatol 2020 May 8. Epub 2020 May 8.

Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.

Objectives: Antioxidant containing cosmeceuticals are commonly prescribed products in treating wrinkles and revitalizing the skin. The aim of this study was the comparative evaluation of physicochemical stability and clinical anti-wrinkle efficacy of transdermal emulgel preparations of sodium ascorbyl phosphate (SAP) and ascorbic acid (AA) on human volunteers.

Methods: Emulgel preparations containing 5% of (SAP) and or (AA) were prepared. Read More

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http://dx.doi.org/10.1111/jocd.13471DOI Listing

Plant In Vitro Systems as a Sustainable Source of Active Ingredients for Cosmeceutical Application.

Molecules 2020 Apr 25;25(9). Epub 2020 Apr 25.

Laboratory of Metabolomics, Department of Biotechnology, The Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 139 Ruski Blvd., 4000 Plovdiv, Bulgaria.

Cosmeceuticals are hybrids between cosmetics and pharmaceuticals which are being designed for a dual purpose: (1) To provide desired esthetical effects and (2) simultaneously treat dermatological conditions. The increased demand for natural remedies and the trends to use natural and safe ingredients resulted in intensive cultivation of medicinal plants. However, in many cases the whole process of plant cultivation, complex extraction procedure, and purification of the targeted molecules are not economically feasible. Read More

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http://dx.doi.org/10.3390/molecules25092006DOI Listing

Marine Collagen from Alternative and Sustainable Sources: Extraction, Processing and Applications.

Mar Drugs 2020 Apr 15;18(4). Epub 2020 Apr 15.

Department of Marine Biotechnology, Stazione Zoologica Anton Dohrn, Villa Comunale, 80121 Napoli, Italy.

Due to its unique properties, collagen is used in the growing fields of pharmaceutical and biomedical devices, as well as in the fields of nutraceuticals, cosmeceuticals, food and beverages. Collagen also represents a valid resource for bioplastics and biomaterials, to be used in the emerging health sectors. Recently, marine organisms have been considered as promising sources of collagen, because they do not harbor transmissible disease. Read More

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http://dx.doi.org/10.3390/md18040214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230273PMC

Chemical Constituents, Antioxidant, Anti-MMPs, and Anti-Hyaluronidase Activities of Lindl. Leaf Extracts for Skin Aging and Skin Damage Prevention.

Molecules 2020 Apr 21;25(8). Epub 2020 Apr 21.

Department of Pharmaceutical Science, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.

This study aimed to investigate the potential usage of Lindl. leaf extracts in the cosmetic industry. Matrix metalloproteinases (MMPs) and hyaluronidase inhibition of leaf extracts, prepared using reflux extraction with deionized water (RE) and 80% ethanol using Soxhlet's apparatus (SE), were determined. Read More

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http://dx.doi.org/10.3390/molecules25081923DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221723PMC

A Review of the Role of Probiotic Supplementation in Dental Caries.

Probiotics Antimicrob Proteins 2020 Apr 19. Epub 2020 Apr 19.

Innovation Center for Holistic Health, Nutraceuticals, and Cosmeceuticals, Faculty of Pharmacy, Chiang Mai University, Chiang Mai, 50200, Thailand.

Dental diseases are among the common health issues experienced around the world. Dental caries is one of the most predominant oral diseases worldwide. Major factors associated with caries development include poor oral hygiene, the content of specific carbohydrates in the diet, dental biofilm formation, the cariogenic microbial load, reduction in salivary flow, insufficient fluoride exposure, gingival recession, genetic factors, and lack of personal attention to one's dental health. Read More

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http://dx.doi.org/10.1007/s12602-020-09652-9DOI Listing

The Role of Microbiome, Dietary Supplements, and Probiotics in Autism Spectrum Disorder.

Int J Environ Res Public Health 2020 Apr 12;17(8). Epub 2020 Apr 12.

Innovation Center for Holistic Health, Nutraceuticals, and Cosmeceuticals, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.

Autism spectrum disorder (ASD) is a serious neurodevelopmental disorder characterized by the impairment of the cognitive function of a child. Studies suggested that the intestinal microbiota has a critical role in the function and regulation of the central nervous system, neuroimmune system and neuroendocrine system. Any adverse changes in the gut-brain axis may cause serious disease. Read More

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http://dx.doi.org/10.3390/ijerph17082647DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215504PMC

Improved Stability of Butterfly Pea Anthocyanins with Biopolymeric Walls.

J Cosmet Sci 2020 Jan/Feb;71(1):1-10

School Of Cosmetic Science, Mae Fah Luang University, Chiang Rai 57100, Thailand (N.L., M.K.), Phytocosmetics And Cosmeceuticals Research Group, Mae Fah Luang University, Chiang Rai 57100, Thailand (N.L., M.K.).

Butterfly pea () anthocyanins are important natural food colorants. However, the instability hinders industrial applications. The butterfly pea anthocyanin extract was prepared and mixed with biopolymeric wall systems such as maltodextrin (MD) and gum arabic (GA), MD and gelatin (GE), and MD and guar gum at 1/4 and 1/5 ratios with or without acidified condition, and assessed using the accelerated stability test. Read More

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Out of your skin.

Authors:
Charlie Schmidt

Nat Biotechnol 2020 04;38(4):392-397

, Portland, ME, USA.

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http://dx.doi.org/10.1038/s41587-020-0473-8DOI Listing

Role of bioactive compounds and other metabolites from mushrooms against skin disorders- a systematic review assessing their cosmeceutical and nutricosmetic outcomes.

Curr Med Chem 2020 Apr 1. Epub 2020 Apr 1.

Centro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança. Portugal.

Bioactive compounds derived from mushrooms have been shown to present promising potential as cosmeceutical or nutricosmetic ingredients. Scientific data reviewed herein showed that extracts prepared from medicinal and edible mushrooms and their individual metabolites presented anti-inflammatory, antioxidant, photoprotective, antimicrobial, anti-tyrosinase, anti-elastase and anti-collagenase activities. These metabolites can be utilised as ingredients to suppress the severity of inflammatory skin diseases, offer photoprotection to the skin and correct hyperpigmentation. Read More

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http://dx.doi.org/10.2174/0929867327666200402100157DOI Listing

Phytochemical Composition, Antioxidant and Antiproliferative Activities of Defatted Sea Buckthorn ( L.) Berry Pomace Fractions Consecutively Recovered by Pressurized Ethanol and Water.

Antioxidants (Basel) 2020 Mar 25;9(4). Epub 2020 Mar 25.

Department of Food Science and Technology, Kaunas University of Technology, Radvilėnų˛ pl. 19, LT-50254 Kaunas, Lithuania.

This study aimed at valorisation of sea buckthorn pomace (SBP) for the production of extracts containing valuable bioactive compounds. For this purpose, SBP defatted by supercritical CO was subjected to consecutive fractionation with pressurized ethanol and water, which yielded 11.9% and 4. Read More

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http://dx.doi.org/10.3390/antiox9040274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7222216PMC

Effects of Astaxanthin Supplementation on Skin Health: A Systematic Review of Clinical Studies.

J Diet Suppl 2020 Mar 23:1-14. Epub 2020 Mar 23.

National University Hospital, National University Health System, Singapore, Singapore.

Astaxanthin (AST), a naturally-occurring keto-carotenoid found in several species of bacteria and microalgae, has demonstrated diverse biological activities and . There is growing commercial interest in the application of astaxanthin in nutraceuticals and cosmeceuticals, due to its purported photoprotective, DNA repair, antioxidant, and anti-inflammatory benefits. This systematic review therefore aimed to summarize current clinical evidence on the effects of astaxanthin supplementation on skin health. Read More

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http://dx.doi.org/10.1080/19390211.2020.1739187DOI Listing

as an emerging biotechnological chassis for functional sugars biosynthesis.

Crit Rev Food Sci Nutr 2020 Mar 17:1-18. Epub 2020 Mar 17.

State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China.

Functional sugars have unique structural and physiological characteristics with applied perspectives for modern biomedical and biotechnological sectors, such as biomedicine, pharmaceutical, cosmeceuticals, green chemistry, and agro-food. They can also be used as starting matrices to produce biologically active metabolites of interests. Though numerous chemical synthesis routes have been proposed and deployed for the synthesis of rare sugars, however, many of them are limited and economically incompetent because of expensive raw starting feedstocks. Read More

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http://dx.doi.org/10.1080/10408398.2020.1739000DOI Listing

Natural resources used as folk cosmeceuticals among rural communities in Vhembe district municipality, Limpopo province, South Africa.

BMC Complement Med Ther 2020 Mar 12;20(1):81. Epub 2020 Mar 12.

School of Biology and Environmental Sciences, Faculty of Agriculture and Natural Sciences, University of Mpumalanga, Private Bag X11283, Mbombela, Mpumalanga Province, 1200, South Africa.

Background: Skin-related diseases affect every individual irrespective of age, gender or social status. Since time immemorial, humans have explored natural resources from their environment for the maintenance of the skin. This explorative survey was conducted to document the natural resources (plant and non-plant materials) used for folk cosmeceuticals by rural communities in Vhembe district municipality, Limpopo province, South Africa. Read More

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http://dx.doi.org/10.1186/s12906-020-2869-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076813PMC

Knowledge about and attitude toward cosmeceuticals among pharmacists in Saudi Arabia.

Authors:
Ahmad A Almeman

J Cosmet Dermatol 2020 Mar 11. Epub 2020 Mar 11.

Pharmacology and Therapeutic Department, College of Medicine, Qassim, Qassim University, Buraidah, Saudi Arabia.

Background: Whitening cosmeceuticals are commonly used for beauty purposes and managing pigmentation disorders. There is significant variability across the world with regard to knowledge as well as legislation of cosmeceuticals.

Aim: To evaluate the knowledge of and attitude toward whitening cosmeceuticals among pharmacists in Saudi Arabia. Read More

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http://dx.doi.org/10.1111/jocd.13358DOI Listing

Areca catechu-From farm to food and biomedical applications.

Phytother Res 2020 Mar 11. Epub 2020 Mar 11.

Zabol Medicinal Plants Research Center, Zabol University of Medical Sciences, Zabol, Iran.

The family Arecaceae includes 181 genera and 2,600 species with a high diversity in physical characteristics. Areca plants, commonly palms, which are able to grow in nearly every type of habitat, prefer tropical and subtropical climates. The most studied species Areca catechu L. Read More

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http://dx.doi.org/10.1002/ptr.6665DOI Listing
March 2020
2.397 Impact Factor

The Role of Probiotics in Colorectal Cancer Management.

Evid Based Complement Alternat Med 2020 14;2020:3535982. Epub 2020 Feb 14.

Innovation Center for Holistic Health, Nutraceuticals, and Cosmeceuticals, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.

Colorectal cancer (CRC) is one of the most common cancerous diseases worldwide and causes leading cancer-associated deaths. Several factors are related to the incidence of CRC such as unhealthy diet and lifestyle, heredity, metabolic disorders, and genetic factors. Even though several advanced medical procedures are available for CRC treatment, the survival rates are poor with many adverse treatments associated side effects, which affects the quality of life. Read More

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http://dx.doi.org/10.1155/2020/3535982DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048916PMC
February 2020

A Supramolecular Approach to Structure-Based Design with A Focus on Synthons Hierarchy in Ornithine-Derived Ligands: Review, Synthesis, Experimental and in Silico Studies.

Molecules 2020 Mar 3;25(5). Epub 2020 Mar 3.

Institute of General and Ecological Chemistry, Faculty of Chemistry, Lodz University of Technology, Żeromskiego 116, 90-924 Lodz, Poland.

The success of innovative drugs depends on an interdisciplinary and holistic approach to their design and development. The supramolecular architecture of living systems is controlled by non-covalent interactions to a very large extent. The latter are prone to extensive cooperation and like a virtuoso play a symphony of life Thus, the design of effective ligands should be based on thorough knowledge on the interactions at either a molecular or high topological level. Read More

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http://dx.doi.org/10.3390/molecules25051135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179192PMC

Oily sensitive skin: A review of management options.

J Cosmet Dermatol 2020 May 29;19(5):1016-1020. Epub 2020 Feb 29.

Department of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea.

Background: Due to the ever-increasing demands for the personalized care, people seek for the tailored management according to the accurate identification of their skin type. The Baumann Skin Type Indicator, which was proposed by Leslie Baumann, is composed of four parameters: oily or dry, resistant or sensitive, pigmented or nonpigmented, and wrinkled or tight. Among these, oily sensitive skin experiences significant discomfort and resists ordinary treatment. Read More

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http://dx.doi.org/10.1111/jocd.13347DOI Listing

Bioactive ingredients in Korean cosmeceuticals: Trends and research evidence.

J Cosmet Dermatol 2020 Jul 26;19(7):1555-1569. Epub 2020 Feb 26.

Department of Dermatology, SUNY Downstate Medical Center, Brooklyn, NY, USA.

Background: Cosmeceuticals are commonly used in skincare regimens to maintain healthy skin and improve visible signs of aging. In recent years, South Korean skincare has gained prominence in the global beauty industry by introducing innovative cosmeceutical products and aesthetic trends.

Objectives: To describe the global impact of Korean skincare and to review the current research evidence for bioactive ingredients commonly found in Korean cosmeceuticals. Read More

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http://dx.doi.org/10.1111/jocd.13344DOI Listing

Formulation and clinical evaluation of the standardized Litchi chinensis extract for skin hyperpigmentation and aging treatments.

Ann Pharm Fr 2020 Mar 23;78(2):142-149. Epub 2020 Jan 23.

School of Cosmetic Science, Mae-Fah-Luang University, 57100 Chiang-Rai, Thailand; Phytocosmetics and Cosmeceuticals Research Group, Mae-Fah-Luang University, 57100 Chiang-Rai, Thailand.

Introduction: The standardized litchi extract had been revealed on phytochemical actives, in vitro and cellular activities against aging and darkening of skin. However, a formulation containing the extract has never been developed as per clinical evaluated.

Materials And Methods: The litchi serum was developed, safety and efficacy were clinically evaluated in human volunteers. Read More

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http://dx.doi.org/10.1016/j.pharma.2020.01.004DOI Listing

SLN enriched hydrogels for dermal application: Full factorial design study to estimate the relationship between composition and mechanical properties.

Chem Phys Lipids 2020 May 7;228:104889. Epub 2020 Feb 7.

Ankara University, Faculty of Pharmacy, Department of Pharmaceutical Technology, Anadolu, 06100, Ankara, Turkey. Electronic address:

When considering dermal administration of cosmeceuticals and/or drugs, the stratum corneum layer of the skin, has a barrier function that limits the penetration of active substances to the targeted skin tissues. Solid lipid nanoparticles/SLNs are colloidal carrier systems, which show superiority in dermal administration of cosmeceuticals/drugs. This superiority results from the ability of the SLNs to penetrate the skin layers easily. Read More

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http://dx.doi.org/10.1016/j.chemphyslip.2020.104889DOI Listing

Microencapsulation of retinyl palmitate by melt dispersion for cosmetic application.

J Microencapsul 2020 May 17;37(3):205-219. Epub 2020 Feb 17.

Innovative Materials Research Group, Department of Textiles, Merchandising and Interiors, University of Georgia, Athens, GA, USA.

Retinyl palmitate was encapsulated in wax matrix by melt dispersion for the purpose of economic and sustainable cosmeceutical formulation with minimum use of synthetic chemicals. We evaluated the effect of different process variables of microencapsulation by melt dispersion. In this study, a three level definitive screening design was applied, where the microcapsule properties were analysed through statistical analysis to understand the effect of four process variables: type of wax, theoretical loading capacity, surface concentration and stirring speed. Read More

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http://dx.doi.org/10.1080/02652048.2020.1720029DOI Listing
May 2020
1.585 Impact Factor

Organic acids and 2,4-Di--butylphenol: major compounds of WM36 cell-free supernatant against growth, survival and virulence of Typhi.

PeerJ 2020 20;8:e8410. Epub 2020 Jan 20.

Innovation Center for Holistic Health, Nutraceuticals and Cosmeceuticals, Faculty of Pharmacy, Chiang Mai University, Chiang Mai, Thailand.

Background: Typhi (. Typhi), the causative agent of typhoid fever, causes serious systemic disease in humans. Antibiotic treatment is required for the . Read More

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http://dx.doi.org/10.7717/peerj.8410DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977521PMC
January 2020

Antihyperglycemic effect of rice husk derived xylooligosaccharides in high-fat diet and low-dose streptozotocin-induced type 2 diabetic rat model.

Food Sci Nutr 2020 Jan 9;8(1):428-444. Epub 2019 Dec 9.

Innovation Center for Holistic Health, Nutraceuticals and Cosmeceuticals Faculty of Pharmacy Chiang Mai University Chiang Mai Thailand.

Rice husk (RH) is an agricultural waste obtained from rice milling process. Our previous study demonstrated the optimized process of extracting xylooligosaccharides (XOS), a prebiotic that can support the growth and activity of beneficial gut microbiota, from RH. Accumulated evidences indicate that the composition of gut microbiota is involved in the progression of insulin resistance and diabetes. Read More

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http://dx.doi.org/10.1002/fsn3.1327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977422PMC
January 2020

Demonstration of the Antioxidant Capabilities of a Product Formulated With Antioxidants Stabilized in Their Reduced Form

J Drugs Dermatol 2020 Jan;19(1):46-49

Oxidative damage from reactive oxygen species is instrumental in aging. Topical antioxidants are used in many cosmeceuticals to provide appearance benefits; however, the activity of these antioxidants may be questionable. This research validated the activity of L-ascorbic acid and L-glutathione in the studied facial product and correlated this activity with clinical appearance improvement following 12 weeks of use. Read More

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http://dx.doi.org/10.36849/JDD.2020.3947DOI Listing
January 2020

Novel Magnesium Aminoclay-Vitamin C Hybrid for Enhanced Stability and Bioactivity in Cosmeceutical Applications.

J Nanosci Nanotechnol 2020 Jul;20(7):4257-4262

Department of BioNano Technology, Gachon University, 1342 Seongnam-Daero, Sujeong-Gu, Seongnam-Si, Gyeonggi-do 13120, Republic of Korea.

Vitamin C (VC) is a hydrophilic antioxidant that plays a vital role in the protection of health and is also an integral ingredient in beauty formulations due to its numerous distinct and necessary properties. However, its application in the area of cosmeceuticals still confronts huge challenges relating to its instability and low bioactivity. Therefore, it is necessary to prevent its degradation by utilizing microencapsulation techniques, many and various of which, entailing the use of liposomes, nanoemulsions, lipid particles, and layered double hydroxide, have already been introduced. Read More

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http://dx.doi.org/10.1166/jnn.2020.17583DOI Listing

Do Probiotics Improve the Health Status of Individuals with Diabetes Mellitus? A Review on Outcomes of Clinical Trials.

Biomed Res Int 2019 14;2019:1531567. Epub 2019 Dec 14.

Innovation Center for Holistic Health, Nutraceuticals, and Cosmeceuticals, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.

Probiotics are now considered as an adjuvant and complementary therapeutic agent for several health complications, especially for metabolic and gastrointestinal disorders because of the influential impact of probiotic consumption on gut microbiota and immunity. Diabetes mellitus (DM) is fourth, in noncommunicable disease category, leading cause of mortality, morbidity, and economic crises in the world. Though several progressions are added in the medical field in recent decades, the treatment and management of diabetic-related health issues are still challenging. Read More

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http://dx.doi.org/10.1155/2019/1531567DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949658PMC

An evaluation of the physicochemical parameters and the content of the active ingredients in original formulas containing retinol.

J Cosmet Dermatol 2020 Jan 9. Epub 2020 Jan 9.

Department of Cosmetic Raw Materials Chemistry, Medical University of Lodz, Lodz, Poland.

Introduction: Three original cosmetic formulations containing retinol as an active component with liquid crystal, lamellar, and lipid bases were prepared. The formulas contain different concentrations of retinol, that is, 0.5%, 0. Read More

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http://dx.doi.org/10.1111/jocd.13286DOI Listing
January 2020

Management of aging skin: A questionnaire-based study among Indian dermatologists.

J Cosmet Dermatol 2019 Dec 30. Epub 2019 Dec 30.

Cipla Ltd., Mumbai, India.

Introduction: With increased life expectancy, the desire to look younger has increased. Hence, many patients approach dermatologists for antiaging treatment. However, data regarding management of skin aging in India are scarce. Read More

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http://dx.doi.org/10.1111/jocd.13279DOI Listing
December 2019

Recent Patents and Discovery of Anti-inflammatory Agents from Marine Source.

Recent Pat Inflamm Allergy Drug Discov 2019 ;13(2):105-114

Shobhaben Pratapbhai Patel- School of Pharmacy & Technology Management, SVKM's NMIMS, V.L. Mehta Road, Vile Parle (W), Mumbai- 400056, Maharashtra, India.

Background: Inflammation has become pathology in the majority of the prevalent diseases such as diabetes, atherosclerosis, epilepsy and neurodegenerative disorders. Anti-inflammatory drugs work wonder in all these conditions, where the patient has become refractory to standard treatment. However, available anti-inflammatory agents have side effects associated with chronic use, thus if we could develop safe and efficacious molecules, quality of health care provided will improve. Read More

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http://dx.doi.org/10.2174/1872213X13666190426164717DOI Listing

Free Radical Scavenging Capability of Various Defatted Sesame Seed Cakes and Hulls Using EPR Compared with In Vitro Testing and HPLC Analysis.

J Oleo Sci 2019 ;68(12):1279-1285

Department of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University.

The free radical scavenging activities of black and white sesame seed hulls and the powder of black and white sesame seed cakes were investigated using noninvasive continuous wave electron paramagnetic resonance (EPR) and antioxidant assays. With black sesame seed hulls and the powder of black sesame seed cakes, EPR detected the very strong single-line signal intensities that correspond to the stable organic radicals, while the spectrum of the white sesame seed hulls and the white sesame seed cakes showed no signal. The in vitro antioxidant activities of black and white sesame seed cake extract were evaluated by DPPH free radical scavenging activity, hydrogen peroxide scavenging activity, and ferric reducing antioxidant power (FRAP) assay. Read More

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http://dx.doi.org/10.5650/jos.ess19203DOI Listing

Role of Liposomes-Based Stem Cell for Multimodal Cancer Therapy.

Stem Cell Rev Rep 2020 Feb;16(1):103-117

Shobhaben Pratapbhai Patel School of Pharmacy and Technology Management, SVKM'S NMIMS, V. L. Mehta road, Vile Parle (W), Mumbai, India.

The utilization of stem cells as novel carriers to target tissues or organs of interest is a challenging task in delivery system. The composite cellular delivery with diverse signalling molecules as therapeutics increases stem cell capability and possesses the promising potential to augment, modify or commence localized or systemic restoration for vital applications in regenerative medicine. The inherent potential of stem cells to immigrate and reside at wounded site facilitates transportation of genes, polypeptides or nanosized molecules. Read More

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http://dx.doi.org/10.1007/s12015-019-09933-zDOI Listing
February 2020