9,975 results match your criteria Corynebacterium Infections


Staphylococcal driveline infections are the predominant type of left ventricular assist device associated infections in Singapore.

Infect Dis (Lond) 2019 Apr 15:1-8. Epub 2019 Apr 15.

a Department of Infectious Diseases , Singapore General Hospital , Singapore.

Background: Left ventricular assist device (LVAD) associated infections (LVADIs) have substantial morbidity and mortality. We aim to describe the incidence and epidemiology of LVADIs in an Asian cohort. This is currently not well studied. Read More

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http://dx.doi.org/10.1080/23744235.2019.1592216DOI Listing
April 2019
1 Read

The detection of intramammary infections using online somatic cell counts.

J Dairy Sci 2019 Apr 3. Epub 2019 Apr 3.

Faculty of Veterinary Medicine, Department of Production Animal Clinical Sciences, Norwegian University of Life Sciences, PO Box 369 Sentrum, N-0102 Oslo, Norway.

Timely and accurate identification of cows with intramammary infections is essential for optimal udder health management. Various sensor systems have been developed to provide udder health information that can be used as a decision support tool for the farmer. Among these sensors, the DeLaval Online Cell Counter (DeLaval, Tumba, Sweden) provides somatic cell counts from every milking at cow level. Read More

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http://dx.doi.org/10.3168/jds.2018-15295DOI Listing
April 2019
1 Read

Corynebacterium kroppenstedtii: a challenging culprit in breast abscesses and granulomatous mastitis.

Curr Opin Obstet Gynecol 2019 Apr 2. Epub 2019 Apr 2.

Department of Pharmacy, Montefiore Medical Center, Wakefield Division.

Purpose Of Review: Corynebacterium kroppenstedtii is a difficult pathogen associated with granulomatous mastitis and recurrent breast abscesses. Despite over a dozen studies, there is no guidance on surgical interventions, steroid use, or dosing or duration of antibiotic treatment.

Recent Findings: Initially seen in predominantly Maori and Pacific Islander multiparous, postlactating women, C. Read More

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http://dx.doi.org/10.1097/GCO.0000000000000541DOI Listing
April 2019
5 Reads

Imported Toxin-Producing Cutaneous Diphtheria - Minnesota, Washington, and New Mexico, 2015-2018.

MMWR Morb Mortal Wkly Rep 2019 Mar 29;68(12):281-284. Epub 2019 Mar 29.

From September 2015 to March 2018, CDC confirmed four cases of cutaneous diphtheria caused by toxin-producing Corynebacterium diphtheriae in patients from Minnesota (two), Washington (one), and New Mexico (one). All patients had recently returned to the United States after travel to countries where diphtheria is endemic. C. Read More

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http://dx.doi.org/10.15585/mmwr.mm6812a2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448983PMC
March 2019
1 Read

Modulation of opportunistic species Corynebacterium diphtheriae, Haemophilus parainfluenzae, Moraxella catarrhalis, Prevotella denticola, Prevotella melaninogenica, Rothia dentocariosa, Staphylococcus aureus and Streptococcus pseudopneumoniae by intranasal administration of Streptococcus salivarius 24SMBc and Streptococcus oralis 89a combination in healthy subjects.

Eur Rev Med Pharmacol Sci 2019 Mar;23(1 Suppl):60-66

Laboratory of Clinical Chemistry and Microbiology, IRCCS Galeazzi Orthopaedic Institute, Milan, Italy.

Objective: Probiotics S. salivarius 24SMBc and S. oralis 89a comprised in the nasal spray Rinogermina are known to exert inhibition of harmful pathogens and ameliorate the outcome of patients with chronic upper airways infections. Read More

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http://dx.doi.org/10.26355/eurrev_201903_17351DOI Listing

Monomicrobial bone and joint infection due to Corynebacterium striatum: literature review and amoxicillin-rifampin combination as treatment perspective.

Eur J Clin Microbiol Infect Dis 2019 Mar 22. Epub 2019 Mar 22.

Infectious Disease Department, Raymond Poincaré University Hospital, APHP, Referral Center for Bone and Joint Infection, UVSQ, 104 Bd R. Poincaré, 92380, Garches, France.

Corynebacterium striatum is a ubiquitous colonizer of human skin and mucous membranes. It is increasingly involved in infections, especially with prosthetic devices or in immunocompromised individuals. Microbiological diagnosis is challenging and bacterial resistance is a major concern. Read More

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http://dx.doi.org/10.1007/s10096-019-03542-xDOI Listing
March 2019
1 Read

Loss of Microbial Topography between Oral and Nasopharyngeal Microbiota and Development of Respiratory Infections Early in Life.

Am J Respir Crit Care Med 2019 Mar 18. Epub 2019 Mar 18.

UMC Utrecht, Pediatric Infectious Diseases & Immunology, Utrecht, Netherlands ;

Rationale: The respiratory microbiota is increasingly being appreciated as an important mediator in the susceptibility to childhood respiratory tract infections (RTIs). Pathogens are presumed to originate from the nasopharyngeal ecosystem.

Objectives: To investigate the association between early-life respiratory microbiota and development of childhood RTIs. Read More

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http://dx.doi.org/10.1164/rccm.201810-1993OCDOI Listing
March 2019
3 Reads

Sonication of Extracted Implants Improves Microbial Detection in Patients With Orthopedic Implant-Associated Infections.

J Arthroplasty 2019 Feb 20. Epub 2019 Feb 20.

Department of Orthopedic Surgery, Kansai Medical University, Hirakata, Osaka, Japan.

Background: We assessed whether combining the conventional culture and implant sonicate fluid culture (SFC) methods increased the diagnostic accuracy of orthopedic implant-associated infection (OIAI).

Methods: Consecutive patients (n = 66) undergoing implant removal (OIAI, 17; non-OIAI, 49) were evaluated prospectively. We analyzed 493 samples (39 preoperative joint aspirates, 243 peri-implant tissue specimens, 124 implant sonication, 67 controls, and 20 water bath samples). Read More

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http://dx.doi.org/10.1016/j.arth.2019.02.020DOI Listing
February 2019

PERITONEAL DIALYSIS CUFF-SHAVING-A SALVAGE THERAPY FOR REFRACTORY EXIT-SITE INFECTIONS.

Perit Dial Int 2019 Mar 6. Epub 2019 Mar 6.

Nefrologia, Centro Hospitalar de São João, Porto, Portugal.

Introduction: Cuff-shaving has been described as a salvage technique for refractory exit-site infections, with conflicting data regarding infection and catheter outcomes. We describe our experience with cuff-shaving as a rescue therapy for exit-site infections unresponsive to systemic therapy.

Methods: We retrospectively reviewed patients who underwent cuff-shaving between January 2012 and June 2017. Read More

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http://dx.doi.org/10.3747/pdi.2018.00193DOI Listing
March 2019
1 Read

Establishment of an objective endpoint in mice model for caseous lymphadenitis vaccine trials.

Vet Microbiol 2019 Mar 19;230:86-89. Epub 2019 Jan 19.

Laboratório de Biotecnologia Infecto-Parasitária, Centro de Desenvolvimento Tecnológico, Biotecnologia, UFPel, Pelotas, RS, 96010-900, Brazil. Electronic address:

For a long time, the scientific community has described the need for a continued update in practices that ensure the welfare of animals undergoing experimentation. In addition to approaches on principles of care and use of animals, there is a more current emerging concern: defining an appropriate end point in experiments that use animals for research, teaching and testing. The term "endpoint" is defined as the point at which an experimental animal's pain and/or distress is terminated, minimized, or reduced humanely. Read More

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http://dx.doi.org/10.1016/j.vetmic.2019.01.017DOI Listing
March 2019
3 Reads

Factors influencing basic vaccination coverage in Myanmar: secondary analysis of 2015 Myanmar demographic and health survey data.

BMC Public Health 2019 Feb 28;19(1):242. Epub 2019 Feb 28.

Bureau of International Health Cooperation, National Center for Global Health and Medicine, 1-21-1, Toyama, Shinjuku, Tokyo, 162-8655, Japan.

Background: Immunization is one of the most effective measures for preventing disease when vaccination coverage is sufficient. Although vaccination coverage is known to be influenced by social and cultural barriers, the determinants of childhood immunization in Myanmar remain poorly understood. This study analyzed factors that influenced complete vaccination status (one dose each for Bacillus Calmette-Guérin and measles and three doses each for diphtheria-pertussis and polio) using 2015 data from the Myanmar Demographic Health and Survey. Read More

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https://bmcpublichealth.biomedcentral.com/articles/10.1186/s
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http://dx.doi.org/10.1186/s12889-019-6548-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394082PMC
February 2019
7 Reads

Parasitic infections during pregnancy need not affect infant antibody responses to early vaccination against Streptococcus pneumoniae, diphtheria, or Haemophilus influenzae type B.

PLoS Negl Trop Dis 2019 02 28;13(2):e0007172. Epub 2019 Feb 28.

Division of Infectious Diseases, Department of Pediatrics, Lucille Packard Children's Hospital at Stanford School of Medicine, Stanford, California, United States of America.

Background: Globally, vaccine-preventable diseases remain a significant cause of early childhood mortality despite concerted efforts to improve vaccine coverage. One reason for impaired protection may be the influence of prenatal exposure to parasitic antigens on the developing immune system. Prior research had shown a decrease in infant vaccine response after in utero parasite exposure among a maternal cohort without aggressive preventive treatment. Read More

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http://dx.plos.org/10.1371/journal.pntd.0007172
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http://dx.doi.org/10.1371/journal.pntd.0007172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413956PMC
February 2019
10 Reads

Corynebacterium urealyticum: rare urinary tract infection with serious complications.

Can J Urol 2019 Feb;26(1):9680-9682

Kaiser Permanente Los Angeles Medical Center, Los Angeles, California, USA.

Corynebacterium urealyticum is an organism associated with a rare chronic urinary tract infection, which can lead to calcification of the urinary tract and promote rapid lithogenesis. This case illustrates the serious complications that can arise from chronic infection with C. urealyticum, which include rapid progression of luminal and parenchymal urinary tract calcification and concomitant renal failure. Read More

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February 2019
2 Reads

Are Sonication Cultures of Antibiotic Cement Spacers Useful During Second-stage Reimplantation Surgery for Prosthetic Joint Infection?

Clin Orthop Relat Res 2018 Oct;476(10):1986-1992

University of Pittsburgh Medical Center, Pittsburgh, PA, USA.

Background: Organisms may persist on polymethylmethacrylate (PMMA) spacer surfaces, and subclinical infection is postulated to be a source of infection recurrence. Several small patient series have shown a high proportion of positive sonication cultures on PMMA spacers at the second stage of a two-stage revision. However, the association between a positive sonication culture and the risk for recurrence of infection after two-stage exchange is not fully elucidated. Read More

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http://dx.doi.org/10.1007/s11999.0000000000000257DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259822PMC
October 2018
2 Reads

Bacterial isolation of milk samples submitted from clinical mastitis buffaloes during 2007 to 2016.

Trop Anim Health Prod 2019 Feb 21. Epub 2019 Feb 21.

Department of Veterinary Medicine, College of Veterinary Science, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, Punjab, 141 004, India.

The present study determined trends in the isolation of bacterial pathogens in milk samples submitted from clinical mastitis buffaloes at the University mastitis laboratory during 2007 to 2016. Culture results (n = 3945) were classified into six categories (Staphylococcus spp., 28. Read More

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http://dx.doi.org/10.1007/s11250-019-01846-wDOI Listing
February 2019

Microbiology of polymicrobial prosthetic joint infection.

Diagn Microbiol Infect Dis 2019 Jan 15. Epub 2019 Jan 15.

Divisions of Clinical Microbiology, Mayo Clinic, Rochester, MN; Infectious Diseases, Mayo Clinic, Rochester, MN. Electronic address:

Prosthetic joint infection (PJI) is a rare but challenging complication of arthroplasty. Herein, we describe the epidemiology and microbiology of PJI, with a focus on analyzing differences between the microbiology of polymicrobial versus monomicrobial infection of hip, knee, and shoulder prostheses. In addition, we report the most frequent co-pathogens in polymicrobial infections, as detected by culture. Read More

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http://dx.doi.org/10.1016/j.diagmicrobio.2019.01.006DOI Listing
January 2019
12 Reads

NGS-based phylogeny of diphtheria-related pathogenicity factors in different Corynebacterium spp. implies species-specific virulence transmission.

BMC Microbiol 2019 Feb 1;19(1):28. Epub 2019 Feb 1.

Bavarian Health and Food Safety Authority, 85764, Oberschleissheim, Germany.

Background: Diphtheria toxin (DT) is produced by toxigenic strains of the human pathogen Corynebacterium diphtheriae as well as zoonotic C. ulcerans and C. pseudotuberculosis. Read More

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http://dx.doi.org/10.1186/s12866-019-1402-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359835PMC
February 2019
1 Read

Validation of monoplex assays detecting antibodies against Corynebacterium diphtheriae and Clostridium tetani toxins, rubella virus and parvovirus B19 for incorporation into Multiplex Serology.

Methods 2019 Apr 28;158:44-53. Epub 2019 Jan 28.

Infections and Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany. Electronic address:

Serological assays detecting antibodies in serum or plasma samples are useful and versatile instruments to investigate an individual's infection and vaccination history, e.g. for clinical diagnosis, personal risk evaluation, and seroepidemiological studies. Read More

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http://dx.doi.org/10.1016/j.ymeth.2019.01.013DOI Listing
April 2019
2 Reads

Molecular epidemiology and clinical significance of isolated from clinical specimens.

Infect Drug Resist 2019 4;12:161-171. Epub 2019 Jan 4.

Division of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Seoul, Republic of Korea,

Purpose: This study investigated the clinical epidemiology, antimicrobial susceptibility, and molecular epidemiology of isolates.

Patients And Methods: An observational study was conducted at a university hospital in the Republic of Korea from August to December 2016. All subjects were patients who tested positive for clinically. Read More

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https://www.dovepress.com/molecular-epidemiology-and-clinica
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http://dx.doi.org/10.2147/IDR.S184518DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324608PMC
January 2019
8 Reads

Clinical description of Corynebacterium urealyticum urinary tract infections in 11 dogs and 10 cats.

J Small Anim Pract 2019 Apr 17;60(4):239-246. Epub 2019 Jan 17.

Ecole Nationale Vétérinaire d'Alfort, Unité de Médecine Interne, 94700 Maisons Alfort, France.

Objectives: To examine the clinical signs, laboratory findings, possible predisposing factors, antimicrobial sensitivity and outcomes of dogs and cats diagnosed with urinary tract infection caused by Corynebacterium urealyticum.

Materials And Methods: Retrospective, observational study of dogs and cats that were diagnosed with urinary tract infection caused by C. urealyticum. Read More

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http://dx.doi.org/10.1111/jsap.12973DOI Listing
April 2019
1 Read

Low-grade infections as a possible cause of arthrofibrosis after total knee arthroplasty.

Patient Saf Surg 2019 10;13. Epub 2019 Jan 10.

Orthopaedic Professorship of the University Hospital Jena, Orthopaedic Department of the Waldkliniken Eisenberg, Eisenberg, Germany.

Purpose: Arthrofibrosis after total knee arthroplasty represents a considerable burden for the patient and a therapeutic challenge for the practitioner. One possible cause discussed in the literature is a low-grade infection. This hypothesis should be examined within the scope of this retrospective study. Read More

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https://pssjournal.biomedcentral.com/articles/10.1186/s13037
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http://dx.doi.org/10.1186/s13037-018-0181-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327456PMC
January 2019
2 Reads

Chlorhexidine 0.5%/70% Alcohol and Iodine 1%/70% Alcohol Both Reduce Bacterial Load in Clean Foot Surgery: A Randomized, Controlled Trial.

J Foot Ankle Surg 2019 Mar 3;58(2):278-281. Epub 2019 Jan 3.

Research Coordinator, Department of Orthopedic Surgery, St. Antonius Hospital, Nieuwegein, the Netherlands. Electronic address:

No consensus exists regarding which cleansing technique, solution, and concentration should be used in orthopedic surgery. The aim of this randomized, controlled trial was to compare the effect of chlorhexidine 0.5%/70% alcohol with iodine 1%/70% alcohol on lowering positive cultures before elective foot surgery and to study any wound complications, infections and allergic reactions. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10672516183038
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http://dx.doi.org/10.1053/j.jfas.2018.08.042DOI Listing
March 2019
10 Reads

Genotypic differences between strains of the opportunistic pathogen Corynebacterium bovis isolated from humans, cows, and rodents.

PLoS One 2018 26;13(12):e0209231. Epub 2018 Dec 26.

Tri-Institutional Training Program in Laboratory Animal Medicine and Science, Memorial Sloan Kettering Cancer Center, Weill Cornell Medicine, and The Rockefeller University, New York, New York, United States of America.

Corynebacterium bovis is an opportunistic bacterial pathogen shown to cause eye and prosthetic joint infections as well as abscesses in humans, mastitis in dairy cattle, and skin disease in laboratory mice and rats. Little is known about the genetic characteristics and genomic diversity of C. bovis because only a single draft genome is available for the species. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0209231PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306256PMC
December 2018
10 Reads

Synergistic and antagonistic effects of Citrus bergamia distilled extract and its major components on drug resistant clinical isolates.

Nat Prod Res 2018 Dec 22:1-4. Epub 2018 Dec 22.

a Department of Health Sciences , Institute of Microbiology, University "Magna Graecia" of Catanzaro , Italy.

In this study we determine the in vitro antimicrobial activities of Citrus bergamia distilled extract and compounds isolated from such extract against clinical MDR strains. The activity of these substances were tested using a broth microdilution assay, their MBC and their FBC to evaluate the nature of the interactions in tested components. Among Gram negative bacteria Enterobacter spp, Klebsiella spp and Pseudomonas spp exhibited the higher MBC values range (2. Read More

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http://dx.doi.org/10.1080/14786419.2018.1522631DOI Listing
December 2018

prosthetic valve endocarditis with severe aortic regurgitation successfully treated with transcatheter aortic valve replacement.

BMJ Case Rep 2018 Nov 28;11(1). Epub 2018 Nov 28.

Department of Medicine, Division of Cardiology, University of Rochester Medical Center, Rochester, New York, USA.

We describe the case of a 69-year-old man with a history of bioprosthetic aortic valve replacement who presented with prosthetic valve endocarditis (PVE) complicated by severe aortic insufficiency with refractory cardiogenic shock despite antibiotic therapy. He was considered a prohibitive-risk surgical candidate due to co-morbid conditions and off-label valve-in-valve transcatheter aortic valve replacement (TAVR) was performed after detailed multidisciplinary evaluation. He recovered well without recurrent infection following completion of antibiotics and transthoracic echocardiogram at 12 months showed a normal functioning prosthetic valve. Read More

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http://www.bmj.com/lookup/doi/10.1136/bcr-2018-226881
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http://dx.doi.org/10.1136/bcr-2018-226881DOI Listing
November 2018
10 Reads

Sir Sheldon Francis Dudley, his Contributions to Diphtheria and the Aftermath of the Sinking of by the .

Ulster Med J 2018 10 1;87(3):188-193. Epub 2018 Oct 1.

David S. Sheridan Professorship in Anaesthesia and Respiratory Therapy, Harvard University, 1400 VFW Parkway, Boston, MA 02132-4927 USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169416PMC
October 2018
1 Read

A Novel Approach to Study the Effect of Ciprofloxacin on Biofilms of spp. Using Confocal Laser Scanning Microscopy.

Pol J Microbiol 2018 ;67(4):431-440

Department of Medical Microbiology, Medical University , Lublin , Poland.

Non-diphtherial corynebacteria are Gram-positive rods that cause opportunistic infections, what is supported by their ability to produce biofilm on artificial surfaces. In this study, the characteristic of the biofilm produced on vascular and urological catheters was determined using a confocal microscopy for the most frequently involved in infections diphtheroid species. They were represented by the reference strains of Corynebacterium striatum ATCC 6940 and C. Read More

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https://www.exeley.com/polish_journal_of_microbiology/doi/10
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http://dx.doi.org/10.21307/pjm-2018-051DOI Listing
January 2018
2 Reads

The polyanions heparin and suramin impede binding of free adenine to a DNA glycosylase from C. pseudotuberculosis.

Int J Biol Macromol 2019 Mar 7;125:459-468. Epub 2018 Dec 7.

Multiuser Center for Biomolecular Innovation, Department of Physics, Instituto de Biociências Letras e Ciências Exatas (Ibilce), Universidade Estadual Paulista (UNESP), São Jose do Rio Preto, SP, 15054-000, Brazil. Electronic address:

Currently no effective treatment is available to combat infections caused by Corynebacterium pseudotuberculosis in livestock. Survival of this Gram-positive bacterium in rapidly-growing pathogens in hostile environments is strongly dependent on the existence of a robust DNA repair system to prevent DNA mutations and contribute to bacterial colonization and virulence. The adenine/guanine-specific DNA glycosylase (MutY) is evolutionarily conserved and has been well characterized due to its central role in the prevention of mutagenesis and DNA repair. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01418130183499
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http://dx.doi.org/10.1016/j.ijbiomac.2018.12.067DOI Listing
March 2019
2 Reads

Immunogenicity and safety of a tetanus-diphtheria vaccine and a 13-valent pneumococcal conjugate vaccine after concomitant vaccination in ≥ 50-year-old adults.

BMC Infect Dis 2018 Dec 5;18(1):628. Epub 2018 Dec 5.

Division of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Seoul, Republic of Korea.

Background: When two or more vaccines are administered concurrently, there is concern about safety and immunogenicity from vaccine interaction.

Methods: Subjects aged ≥50 years were randomized 1:1:1 to receive tetanus-diphtheria (Td) + 13-valent pneumococcal conjugate vaccine (PCV13; Group 1), PCV13 alone (Group 2), or Td alone (Group 3). After single or concomitant vaccination, enzyme-linked immunosorbent assay and opsonophagocytic assay (OPA) were performed to compare immunogenicity for Td and PCV13, respectively. Read More

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http://dx.doi.org/10.1186/s12879-018-3479-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282243PMC
December 2018
3 Reads

What is the importance of vaccine hesitancy in the drop of vaccination coverage in Brazil?

Rev Saude Publica 2018 Nov 29;52:96. Epub 2018 Nov 29.

Universidade de São Paulo. Faculdade de Saúde Pública. Departamento de Epidemiologia. São Paulo, SP, Brasil.

The successful Programa Nacional de Imunizações do Brasil (Brazilian National Immunization Program) has been experiencing a major challenge with regard to vaccination coverage for children, which has been dropping. Several aspects are related, but certainly vaccine hesitancy has been strengthening itself as one of the main concerns of Brazilian public administrators and researchers. Vaccine hesitancy is the delay in acceptance or refusal despite having the recommended vaccines available in health services, being a phenomenon that varies over time, over location and over types of vaccines. Read More

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http://dx.doi.org/10.11606/S1518-8787.2018052001199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284490PMC
November 2018
19 Reads

Genome-wide comparison of Corynebacterium diphtheriae isolates from Australia identifies differences in the Pan-genomes between respiratory and cutaneous strains.

BMC Genomics 2018 Dec 4;19(1):869. Epub 2018 Dec 4.

Centre for Infectious Diseases and Microbiology, Westmead Hospital, PO Box 533, Wentworthville, NSW, 2145, Australia.

Background: Corynebacterium diphtheriae is the main etiological agent of diphtheria, a global disease causing life-threatening infections, particularly in infants and children. Vaccination with diphtheria toxoid protects against infection with potent toxin producing strains. However a growing number of apparently non-toxigenic but potentially invasive C. Read More

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http://dx.doi.org/10.1186/s12864-018-5147-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278121PMC
December 2018
2 Reads

Molecular characterization of Corynebacterium diphtheriae isolates in Malaysia between 1981 and 2016.

J Med Microbiol 2019 Jan 22;68(1):105-110. Epub 2018 Nov 22.

2​Bacteriology Unit, Infectious Disease Research Centre, Institute for Medical Research, Kuala Lumpur, Malaysia.

Sporadic diphtheria cases in Malaysia have remained low in number since the 1990s. However, in 2016 a total of 31 cases were reported nationwide and to investigate this we performed molecular characterization of 30 Corynebacterium diphtheriae isolates collected from 1981 to 2016 using multilocus sequence typing (MLST). C. Read More

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http://www.microbiologyresearch.org/content/journal/jmm/10.1
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http://dx.doi.org/10.1099/jmm.0.000881DOI Listing
January 2019
9 Reads

Cystic neutrophilic granulomatous mastitis: The Cleveland Clinic experience with diagnosis and management.

Breast J 2019 01 17;25(1):80-85. Epub 2018 Nov 17.

Department of Pathology, Cleveland Clinic, Cleveland, Ohio.

Granulomatous mastitis is an uncommon inflammatory disease that typically presents with painful breast lesions. Recent publications have brought to light a specific subset of granulomatous mastitis patients with a distinct histological pattern of disease termed, "cystic neutrophilic granulomatous mastitis" (CNGM). Although many cases of granulomatous lobular mastitis have been thought to be idiopathic, this rare subset of an uncommon disease has been linked to infections with Corynebacterium species. Read More

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http://dx.doi.org/10.1111/tbj.13160DOI Listing
January 2019
25 Reads

Total nephrectomy following urinary tract infection.

JMM Case Rep 2018 Sep 6;5(9):e005149. Epub 2018 Apr 6.

Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica, Departamento de Bioquímica Clínica, Cátedra de Microbiología Clínica, Hospital de Clínicas José de San Martín, Ciudad Autónoma de Buenos Aires, Argentina.

Introduction: is a Gram-stain-positive non-lipophilic coryneform rod first described in blood samples and pleural fluid. There is scarce information about the clinical relevance of and none on complicated urinary tract infections has been described so far.

Case Presentation: A 36-year-old woman with a history of chronic kidney failure, under thrice-weekly haemodialysis since 2014 due to polycystic kidney disease, presented with hypogastric pain, lower left quadrant pain and nausea. Read More

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http://www.microbiologyresearch.org/content/journal/jmmcr/10
Publisher Site
http://dx.doi.org/10.1099/jmmcr.0.005149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230760PMC
September 2018
16 Reads

Treatment considerations for potential uropathogens detected by precision microbiological testing.

Am J Health Syst Pharm 2018 Nov;75(22):1775-1782

Department of Pharmacy Practice, University of Illinois at Chicago College of Pharmacy, Rockford, IL.

Purpose: The clinical and microbiological data for urinary tract infections (UTIs) for 6 organisms detected by matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) at community health systems were examined.

Summary: The use of precision microbiological diagnostic testing such as MALDI-TOF and real-time quantitative polymerase chain reaction has increased the ability to detect a wider spectrum of organisms. This has raised questions of the clinical relevance of infrequently encountered organisms, especially when cultured from urine. Read More

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http://dx.doi.org/10.2146/ajhp180208DOI Listing
November 2018

Evaluation of fast-acting bactericidal activity and substantivity of an antiseptic agent, olanexidine gluconate, using an ex vivo skin model.

J Med Microbiol 2018 Dec 7;67(12):1796-1803. Epub 2018 Nov 7.

Naruto Research Institute, Research and Development Center, Otsuka Pharmaceutical Factory, Inc., Naruto, Tokushima, Japan.

Purpose: We assessed the fast-acting bactericidal activity and substantivity of olanexidine gluconate (OLG) to investigate its remaining bactericidal activity on the skin after rinsing and drying by using an ex vivo Yucatan micropig (YMP) skin model.

Methodology: The fast-acting bactericidal activity was evaluated in pigskin models inoculated with methicillin-resistant Staphylococcus aureus (MRSA), Staphylococcus epidermidis, vancomycin-resistant Enterococcus faecalis (VRE), Acinetobacter baumannii, Corynebacterium minutissimum and Cutibacterium acnes. To evaluate substantivity, the YMP skin piece first had 1. Read More

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http://www.microbiologyresearch.org/content/journal/jmm/10.1
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http://dx.doi.org/10.1099/jmm.0.000870DOI Listing
December 2018
19 Reads

HPV infection and bacterial microbiota in breast milk and infant oral mucosa.

PLoS One 2018 5;13(11):e0207016. Epub 2018 Nov 5.

Department of Oral Pathology and Oral Radiology, Institute of Dentistry, Faculty of Medicine, University of Turku, Turku, Finland.

Objective: We investigated the association between bacterial microbiota in breast milk and the infant mouth. The influence of human papilloma virus (HPV) infection on infant oral microbiota was also assessed.

Material And Methods: Altogether 35 breast milk and 35 infant oral samples with known HPV status were selected from the Finnish Family HPV Study cohort. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0207016PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218085PMC
April 2019
12 Reads

A SNP-based phylogenetic analysis of Corynebacterium diphtheriae in Malaysia.

BMC Res Notes 2018 Oct 25;11(1):760. Epub 2018 Oct 25.

Molecular Diagnostics and Protein Unit, Specialised Diagnostics Centre, Institute for Medical Research, Jalan Pahang, Kuala Lumpur, 50588, Wilayah Persekutuan Kuala Lumpur, Malaysia.

Objective: There is a lack of study in Corynebacterium diphtheriae isolates in Malaysia. The alarming surge of cases in year 2016 lead us to evaluate the local clinical C. diphtheriae strains in Malaysia. Read More

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http://dx.doi.org/10.1186/s13104-018-3868-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203263PMC
October 2018
1 Read

Influence of midgut microbiota in Anopheles stephensi on Plasmodium berghei infections.

Malar J 2018 Oct 25;17(1):385. Epub 2018 Oct 25.

ICMR-National Institute of Malaria Research, Sector 8, Dwarka, New Delhi, 110077, India.

Background: The native gut microbiota of Anopheles mosquitoes is known to play a key role in the physiological function of its host. Interestingly, this microbiota can also influence the development of Plasmodium in its host mosquitoes. In recent years, much interest has been shown in the employment of gut symbionts derived from vectors in the control of vector-borne disease transmission. Read More

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https://malariajournal.biomedcentral.com/articles/10.1186/s1
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http://dx.doi.org/10.1186/s12936-018-2535-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203276PMC
October 2018
15 Reads

Native Aortic Valve Endocarditis in a Patient With Prosthetic Mitral Valve: A Rare Presentation.

Cardiol Res 2018 Oct 7;9(5):314-317. Epub 2018 Oct 7.

International Emerging Infections Program ( IEIP), Thailand MOPH-US CDC, Collabolation, Nontaburi, Thailand.

Infective endocarditis due to non-toxigenic is uncommon. We describe the case of a 42-year-old male with a history of mitral valve replacement with prosthetic valve for 4 years. He presented with fever, weight loss, dyspnea on exertion and orthopnea. Read More

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http://www.cardiologyres.org/index.php/Cardiologyres/article
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http://dx.doi.org/10.14740/cr741wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188043PMC
October 2018
17 Reads

Application of benchmark analysis for mixed contaminant exposures: Mutual adjustment of perfluoroalkylate substances associated with immunotoxicity.

PLoS One 2018 19;13(10):e0205388. Epub 2018 Oct 19.

Department of Environmental Medicine, University of Southern Denmark, Odense, Denmark.

Background: Developmental exposure to perfluorinated alkylate substances (PFASs) is associated with deficient IgG antibody responses to childhood vaccines. As this immunotoxicity outcome may represent a critical effect, calculation of benchmark dose (BMD) results would be useful for defining protective limits of exposure. However, exposures to the major PFASs that are associated with this adverse effect are interrelated, and mutually adjusted BMD results would be desirable. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0205388PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6195268PMC
March 2019
1 Read

Adult Diphtheria Vaccination.

Authors:
Iris Rengganis

Acta Med Indones 2018 Jul;50(3):268-272

Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia.

Low adult vaccination coverage in Indonesia may contribute to a recent outbreak of diphtheria in Indonesia. Although well known as a pediatric vaccine, diphtheria vaccination should be administered as booster to adolescence and adults for longer prevention. Adult vaccine differs from pediatric vaccine but have similar protection. Read More

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July 2018
1 Read

[Quantifying the impact of mass vaccination programmes on notified cases in the Netherlands].

Ned Tijdschr Geneeskd 2018 09 20;162. Epub 2018 Sep 20.

Centrum Infectieziektebestrijding, RIVM, Bilthoven, Nederland.

Objective: To quantify the impact of long-standing vaccination programmes on notified cases in the Netherlands.

Design: Estimates based on model projections of historical morbidity data.

Method: We collected and digitised previously unavailable monthly case notifications of diphtheria, poliomyelitis, mumps and rubella in the Netherlands over the period 1919-2015. Read More

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September 2018
4 Reads

Species Rarely Cause Orthopedic Infections.

J Clin Microbiol 2018 Dec 27;56(12). Epub 2018 Nov 27.

Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland

spp. are rarely considered pathogens, but data on spp. as a cause of orthopedic infections are sparse. Read More

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http://jcm.asm.org/lookup/doi/10.1128/JCM.01200-18
Publisher Site
http://dx.doi.org/10.1128/JCM.01200-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258853PMC
December 2018
3 Reads

[Analysis on the distribution and drug resistance features of anaerobes isolated from clinical infectious specimens].

Zhonghua Yi Xue Za Zhi 2018 Sep;98(36):2894-2898

Department of Clinical Laboratory, Affiliated Hospital of Inner Mongolian Medical University, Hohhot 010050, China.

To clarify distribution and drug resistance characteristics of anaerobes isolated from clinical infectious samples, and to provide experimental data for guiding on treatment of infections caused by anaerobes. The anaerobes, isolated from 1 057 different clinical specimens from inpatients admitted to the Affiliated Hospital of Inner Mongolia Medical University from March 2016 to November 2017, were identified by VITEK-2 anaerobes and corynebacterium (ANC) card and bacteroides fragilis isolates were further verified by 16S-rRNA sequencing. Meanwhile, broth dilution method was employed to detect the drug sensititities of and PCR method was used to detect the carbapenem resistance gene cfiA. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2018.36.004DOI Listing
September 2018
1 Read

Transmission of toxigenic by a fully immunised resident returning from a visit to West Africa, United Kingdom, 2017.

Euro Surveill 2018 Sep;23(39)

Field Epidemiology Service, Public Health England, Cambridge, United Kingdom.

In early 2017, a United Kingdom (UK)-born person in their 20s presented with a skin ulcer on the foot 3 weeks after returning from Ghana. The patient had last received a diphtheria-containing vaccine in 2013, completing the recommended course. MALDI-TOF of a cutaneous swab identified . Read More

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http://dx.doi.org/10.2807/1560-7917.ES.2018.23.39.1700681DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169202PMC
September 2018
5 Reads

Factors impairing cell proliferation in the granulation tissue of pressure ulcers: Impact of bacterial burden.

Wound Repair Regen 2018 05 17;26(3):284-292. Epub 2018 Oct 17.

Department of Plastic and Reconstructive Surgery, Saitama Medical University, Saitama, Japan.

The authors aimed to assess the factors that impair cell proliferation in the granulation tissue of pressure ulcers using immunohistochemistry for the cell proliferation marker Ki-67. This was a single center, cross-sectional study. The study included 86 patients with stage III or IV pressure ulcers. Read More

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http://doi.wiley.com/10.1111/wrr.12675
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http://dx.doi.org/10.1111/wrr.12675DOI Listing
May 2018
6 Reads

Biogenic fabrication and characterization of silver nanoparticles using aqueous-ethanolic extract of lichen () and their antimicrobial activity.

Biomater Res 2018 21;22:23. Epub 2018 Sep 21.

4Department of Ilmul Advia (Unani Pharmacy), Aligarh Muslim University, Aligarh, Uttar Pradesh 202002 India.

Background: Biogenic fabrication of silver nanoparticles from naturally occurring biomaterials provides an alternative, eco-friendly and cost-effective means of obtaining nanoparticles. It is a favourite pursuit of all scientists and has gained popularity because it prevents the environment from pollution. Our main objective to take up this project is to fabricate silver nanoparticles from lichen, and explore their properties. Read More

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https://biomaterialsres.biomedcentral.com/articles/10.1186/s
Publisher Site
http://dx.doi.org/10.1186/s40824-018-0135-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151007PMC
September 2018
23 Reads

Novel association of Psychrobacter and Pseudomonas with malodour in bloodhound dogs, and the effects of a topical product composed of essential oils and plant-derived essential fatty acids in a randomized, blinded, placebo-controlled study.

Vet Dermatol 2018 Dec 24;29(6):465-e158. Epub 2018 Sep 24.

Department of Veterinary Pathobiology, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, 4467 TAMU, College Station, TX, 77843, USA.

Background: The pathogenesis and treatment of cutaneous malodour in dogs have not been investigated previously. Staphylococcus and Corynebacterium spp. are associated with human axillary malodour. Read More

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http://dx.doi.org/10.1111/vde.12689DOI Listing
December 2018
4 Reads
1.732 Impact Factor

Cystic neutrophilic granulomatous mastitis: A clinicopathologic study of a distinct entity with supporting evidence of a role for Corynebacterium-targeted therapy.

Ann Diagn Pathol 2018 Dec 24;37:51-56. Epub 2018 Aug 24.

Department of Pathology and Laboratory Medicine, Western Connecticut Health Network, Danbury, CT, USA.

Cystic neutrophilic granulomatous mastitis (CNGM) is a distinct histopathologic entity characterized by neutrophilic and granulomatous inflammation surrounding clear cystic spaces. Rare gram-positive bacilli are sometimes identified within these cystic spaces. Studies in the literature have identified these gram-positive bacilli to be Corynebacterium species. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10929134183020
Publisher Site
http://dx.doi.org/10.1016/j.anndiagpath.2018.08.005DOI Listing
December 2018
23 Reads