20,828 results match your criteria Coronary CT Angiography


Effect of tube potential and luminal contrast attenuation on atherosclerotic plaque attenuation by coronary CT angiography: In vivo comparison with intravascular ultrasound.

J Cardiovasc Comput Tomogr 2019 Feb 12. Epub 2019 Feb 12.

Department of Imaging, Cedars-Sinai Medical Center, Los Angeles, CA, USA; The Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

Background: It has been shown that CT attenuation of noncalcified plaques depends on luminal contrast attenuation (LCA). Although tube potential (kilovolt [kV]) has been shown to exert influence on plaque attenuation through LCA as well as its direct effects, in-vivo studies have not investigated plaque attenuation at lower tube potentials less than 120 kV. We sought to evaluate the effect of kV and LCA on thresholds for lipid-rich and fibrous plaques as defined by intravascular ultrasound (IVUS). Read More

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http://dx.doi.org/10.1016/j.jcct.2019.02.004DOI Listing
February 2019

Coronary Physiology in the Cardiac Catheterization Laboratory.

J Clin Med 2019 Feb 18;8(2). Epub 2019 Feb 18.

Yale-New Haven Hospital, Yale School of Medicine, New Haven, CT 06510, USA.

Coronary angiography has been the principle modality for assessing the severity of atherosclerotic coronary artery disease for several decades. However, there is a complex relationship between angiographic coronary stenosis and the presence or absence of myocardial ischemia. Recent technological advances now allow for the assessment of coronary physiology in the catheterization laboratory at the time of diagnostic coronary angiography. Read More

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http://dx.doi.org/10.3390/jcm8020255DOI Listing
February 2019

A Review of the Role of Breast Arterial Calcification for Cardiovascular Risk Stratification in Women.

Circulation 2019 Feb;139(8):1094-1101

Division of Cardiovascular Medicine, Department of Medicine, University of California, San Diego.

Cardiovascular disease continues to be the leading cause of death among women in the United States. One of the barriers to improving cardiovascular disease outcomes in women is the lack of reliable, effective screening modalities. Breast arterial calcification has emerged as a potential risk stratification tool. Read More

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.038092DOI Listing
February 2019

Using radiation safely in cardiology: what imagers need to know.

Heart 2019 Feb 18. Epub 2019 Feb 18.

Centre for Cardiovascular Sciences, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1136/heartjnl-2017-312493DOI Listing
February 2019

Impact of single phase CT angiography collateral status on functional outcome over time: results from the MR CLEAN Registry.

J Neurointerv Surg 2019 Feb 18. Epub 2019 Feb 18.

Radiology & Nuclear Medicine, Amsterdam University Medical Center (AMC), Amsterdam, The Netherlands.

Background: Collateral status modified the effect of endovascular treatment (EVT) for stroke in several randomized trials. We assessed the association between collaterals and functional outcome in EVT treated patients and investigated if this association is time dependent.

Methods: We included consecutive patients from the Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in The Netherlands (MR CLEAN) Registry (March 2014-June 2016) with an anterior circulation large vessel occlusion undergoing EVT. Read More

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http://dx.doi.org/10.1136/neurintsurg-2018-014619DOI Listing
February 2019

Association of epicardial adipose tissue attenuation with coronary atherosclerosis in patients with a high risk of coronary artery disease.

Atherosclerosis 2019 Feb 6. Epub 2019 Feb 6.

Department of Cardiac Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, PR China. Electronic address:

Background And Aims: Density may indicate some tissue characteristics and help reveal the role of epicardial adipose tissue (EAT) in coronary artery disease (CAD). Therefore, we assessed the association of EAT density with the coronary artery plaque burden in patients presenting with chest pain.

Methods: This retrospective cohort study comprised 614 patients (mean age 61 ± 9 years, 61% males) with a high cardiovascular disease risk, who underwent cardiac computed tomography angiography. Read More

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http://dx.doi.org/10.1016/j.atherosclerosis.2019.01.033DOI Listing
February 2019

Relationship between coronary atherosclerosis in coronary computed tomography angiography and serum vitamin D level.

Osteoporos Sarcopenia 2017 Sep 5;3(3):155-158. Epub 2017 Sep 5.

Department of Family Medicine, Konyang University Hospital, Daejeon, South Korea.

Objectives: Vitamin D deficiency has been shown to influence the development of some cardiovascular disease. In this study, the association between the existence of coronary artery plaque and vitamin D was examined among participants who were not previously diagnosed with coronary artery disease.

Methods: A total of 339 participants (246 men and 93 women) who visited a health examination center for check-up including blood test for serum vitamin D level and coronary computed tomography angiography (CCTA) were selected for this study. Read More

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http://dx.doi.org/10.1016/j.afos.2017.08.100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372824PMC
September 2017

JCL roundtable: Coronary artery calcium scoring and other vascular imaging for risk assessment.

J Clin Lipidol 2019 Jan - Feb;13(1):4-14

Division of Endocrinology, Metabolism, and Nutrition, Department of Medicine, Duke University Medical Center, Durham, NC, USA. Electronic address:

Computed tomographic (CT) coronary calcium scoring has been established by large prospective, population-based studies as the single best noninvasive predictor of atherosclerotic cardiovascular risk available today. The calcium score correlates highly with the total burden of coronary atherosclerosis demonstrated at autopsy. It adds significantly to traditional risk calculators such as the Framingham Risk Calculator or the Pooled Cohort Equations. Read More

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http://dx.doi.org/10.1016/j.jacl.2019.01.008DOI Listing
February 2019
1 Read

Circle of Willis variations in migraine patients with ischemic stroke.

Brain Behav 2019 Feb 16:e01223. Epub 2019 Feb 16.

Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands.

Objectives: Migraine is a risk factor for stroke, which might be explained by a higher prevalence in anatomical variants in the circle of Willis (CoW). Here, we compared the presence of CoW variants in patients with stroke with and without migraine.

Materials And Methods: Participants were recruited from the prospective Dutch acute Stroke Study. Read More

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http://dx.doi.org/10.1002/brb3.1223DOI Listing
February 2019
1 Read

Detecting Coronary Inflammation With Perivascular Fat Attenuation Imaging: Making Sense From Perivascular Attenuation Maps.

JACC Cardiovasc Imaging 2019 Feb 11. Epub 2019 Feb 11.

Department of Cardiology, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom; Caristo Diagnostics, Oxford, United Kingdom.

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http://dx.doi.org/10.1016/j.jcmg.2018.12.024DOI Listing
February 2019

Peri-Coronary Adipose Tissue Density Is Associated With F-Sodium Fluoride Coronary Uptake in Stable Patients With High-Risk Plaques.

JACC Cardiovasc Imaging 2019 Feb 11. Epub 2019 Feb 11.

Department of Imaging (Division of Nuclear Medicine), Medicine, and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California. Electronic address:

Objectives: This study aimed to assess the association between increased lesion peri-coronary adipose tissue (PCAT) density and coronary F-sodium fluoride (F-NaF) uptake on positron emission tomography (PET) in stable patients with high-risk coronary plaques (HRPs) shown on coronary computed tomography angiography (CTA).

Background: Coronary F-NaF uptake reflects the rate of calcification of coronary atherosclerotic plaque. Increased PCAT density is associated with vascular inflammation. Read More

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http://dx.doi.org/10.1016/j.jcmg.2018.11.032DOI Listing
February 2019
1 Read

Clinical and Computed Tomography Angiographic Predictors of Coronary Lesions That Later Progressed to Chronic Total Occlusion.

JACC Cardiovasc Imaging 2019 Feb 11. Epub 2019 Feb 11.

Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea.

Objectives: This study aimed to investigate clinical and coronary computed tomographic angiography (CTA) characteristics of lesions that progressed to chronic total occlusion (CTO).

Background: CTO is one of the most common reasons for referral to coronary artery bypass surgery. Prediction and adequate early management for future CTO lesions may be beneficial. Read More

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http://dx.doi.org/10.1016/j.jcmg.2018.12.026DOI Listing
February 2019

Is contrast-enhanced ultrasound (CEUS) superior to computed tomography angiography (CTA) in detection of endoleaks in post-EVAR patients? A systematic review and meta-analysis.

J Ultrasound 2019 Feb 15. Epub 2019 Feb 15.

Department of Vascular Surgery, Countess of Chester Hospital, Chester, CH2 1UL, UK.

Objective: The purpose of this systematic review and meta-analysis was to assess the sensitivity and specificity of contrast-enhanced ultrasound (CEUS) compared to computed tomography angiography (CTA) for the detection of endoleaks within endovascular aortic aneurysm repair (EVAR) surveillance at time of follow up.

Methods: A comprehensive literature search was undertaken among the four major databases (PubMed, Embase, Scopus and Ovid) to identify all articles assessing diagnostic specificity and accuracy with comparative modality (CEUS vs CTA) for endoleaks in adult patients at time of follow-up following EVAR. Databases where evaluated and assessed to October 2018. Read More

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http://dx.doi.org/10.1007/s40477-019-00364-7DOI Listing
February 2019

A plethora of manifestations following a Mycoplasma pneumoniae infection: a case report.

Acta Clin Belg 2019 Feb 15:1-6. Epub 2019 Feb 15.

e Department of Gastroenteroly , AZ Maria Middelares , Ghent , Belgium.

Mycoplasma pneumoniae infection can present with a plethora of symptoms and result in a systemic vasculitis by activating a cascade of autoimmune reactions. In this case report, a young man without relevant past medical history was admitted to the hospital with diarrhea, abdominal pain and spiking fever. A CT-scan showed terminal ileitis. Read More

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http://dx.doi.org/10.1080/17843286.2019.1578029DOI Listing
February 2019
1 Read

Abnormal Fractional Flow Reserve in Nonobstructive Coronary Artery Disease.

Circ Cardiovasc Interv 2019 Feb;12(2):e006961

Division of Cardiology, Gifu Heart Center, Japan (S.I., T.K., Y.K., H.M.).

Background The basis of discordance between invasive coronary angiographic (ICA) anatomic stenosis and fractional flow reserve (FFR) is not fully understood. We analyzed coronary computed tomography angiography (CTA) characteristics of ICA-verified nonobstructive lesions in the proximal or midleft anterior descending artery with FFR ≤0.8, that is, anatomy-physiology mismatch. Read More

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https://www.ahajournals.org/doi/10.1161/CIRCINTERVENTIONS.11
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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.118.006961DOI Listing
February 2019
2 Reads

Recurrent myocardial infarction in a 50-year-old woman.

Heart 2019 Feb 14. Epub 2019 Feb 14.

University Hospital Hairmyres, East Kilbridge, UK.

CLINICAL INTRODUCTION: A 50-year-old woman presented with an inferoposterior ST-elevation myocardial infarction (STEMI) and underwent emergency percutaneous coronary intervention (PCI). Angiography revealed acute occlusion of the circumflex and right coronary (RCA) arteries. PCI was uncomplicated. Read More

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http://heart.bmj.com/lookup/doi/10.1136/heartjnl-2018-314114
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http://dx.doi.org/10.1136/heartjnl-2018-314114DOI Listing
February 2019
2 Reads

Coronary Artery Disease-Reporting and Data System (CAD-RADS): strengths and limitations.

Clin Radiol 2019 Feb 11. Epub 2019 Feb 11.

Department of Radiology, Heart Hospital, Hamad Medical Corporation, PO Box: 82228, Doha, Qatar.

A new standardised reporting system was introduced recently for coronary computed tomography (CT) angiography interpretation called CAD-RADS (Coronary Artery Disease-Reporting and Data System). Like any other new reporting platform, CAD-RADS has both advantages and disadvantages. Consistency in reporting, better clarity of communication, and more streamlined clinical recommendations are the major strengths of CAD-RADS. Read More

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http://dx.doi.org/10.1016/j.crad.2019.01.003DOI Listing
February 2019

Contemporary Discrepancies of Stenosis Assessment by Computed Tomography and Invasive Coronary Angiography.

Circ Cardiovasc Imaging 2019 Feb;12(2):e007720

Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD (Y.B.S., A.A.-Z., M.R.O., A.L.V., J.B., J.A.C.L., J.M.M.).

Background Ongoing advancements of coronary computed tomographic angiography (CTA) continue to challenge the role of invasive coronary angiography (ICA) as the gold standard for the evaluation of coronary artery disease (CAD). We sought to investigate the diagnostic accuracy of 320-slice CTA for detecting obstructive CAD in reference to ICA and nuclear myocardial perfusion imaging using single-photon emission computed tomography. Methods For the CORE320 study (Coronary Artery Evaluation Using 320-Row Multidetector Computed Tomography Angiography and Myocardial Perfusion), 381 patients at 16 centers underwent CTA, nuclear myocardial perfusion imaging by single-photon emission computed tomography, and ICA for the evaluation of CAD. Read More

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http://dx.doi.org/10.1161/CIRCIMAGING.118.007720DOI Listing
February 2019
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Computed Tomography to Replace Invasive Coronary Angiography?

Authors:
Paul Knaapen

Circ Cardiovasc Imaging 2019 Feb;12(2):e008710

Department of Cardiology, VU University Medical Center, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1161/CIRCIMAGING.119.008710DOI Listing
February 2019

Does the Tube Voltage Affect the Characterization of Coronary Plaques on 100- and 120-kVp Computed Tomography Scans.

J Comput Assist Tomogr 2019 Feb 11. Epub 2019 Feb 11.

Department of Diagnostic Radiology, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima.

Objective: The aim of this study was to compare the diagnostic performance of 100- and 120-kVp coronary computed tomography (CT) angiography (CCTA) scans for the identification of coronary plaque components.

Methods: We included 116 patients with coronary plaques who underwent CCTA and integrated backscatter intravascular ultrasound studies. On 100-kVp scans, we observed 24 fibrous and 24 fatty/fibrofatty plaques; on 120-kVp scans, we noted 27 fibrous and 41 fatty/fibrofatty plaques. Read More

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http://dx.doi.org/10.1097/RCT.0000000000000845DOI Listing
February 2019

Obstructive and non-obstructive coronary artery disease in long-lasting type 1 diabetes: a 7-year prospective cohort study.

Pol Arch Intern Med 2019 Feb 13. Epub 2019 Feb 13.

INTRODUCTION It is widely believed that patients with diabetes are at increased risk of severe and premature coronary artery disease (CAD) when compared to non-diabetic individuals. OBJECTIVES To evaluate the prevalence, 7-year incidence, predictors, and outcomes of obstructive and non-obstructive CAD in patients with long-lasting type 1 diabetes. PATIENTS AND METHODS We enrolled 2330 patients at a median age of 50 years with a median diabetes duration of 32 years. Read More

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http://dx.doi.org/10.20452/pamw.4440DOI Listing
February 2019
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Coronary CT Angiography in Challenging Patients: High Heart Rate and Atrial Fibrillation. A Review.

Acad Radiol 2019 Feb 8. Epub 2019 Feb 8.

Centro Cardiologico Monzino, IRCCS, Milan, Italy; Department of Clinical Sciences and Community Health, Cardiovascular Section, University of Milan, Via C. Parea 4, 20138 Milan, Italy. Electronic address:

Despite several strategies have been developed by different vendors to improve image quality and diagnostic accuracy of coronary CT angiography performed at high heart rate (HR) and HR variability, as in patients with atrial fibrillation (AF), some concerns and small clinical experience characterize these subsets of challenging patients. However, patients with AF have been reported to have higher risk of cardiovascular events and noninvasive evaluation of suspected coronary artery disease in this setting may be of extreme clinical interest. The goal of this review is to provide to the reader an overview on the use of cardiac CT in patients with AF and high HR and to outline the technological improvements recently introduced in the clinical field that may enable to definitively overcome the limitations of cardiac CT in this challenging scenario. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10766332193005
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http://dx.doi.org/10.1016/j.acra.2019.01.022DOI Listing
February 2019
3 Reads

A cross-sectional survey of coronary plaque composition in individuals on non-statin lipid lowering drug therapies and undergoing coronary computed tomography angiography.

J Cardiovasc Comput Tomogr 2019 Jan 29. Epub 2019 Jan 29.

Department of Radiology, New York-Presbyterian Hospital and Weill Cornell Medicine, New York, NY, USA. Electronic address:

Introduction: Non-statin therapy (NST) is used as second-line treatment when statin monotherapy is inadequate or poorly tolerated.

Objective: To determine the association of NST with plaque composition, alone or in combination with statins, in patients undergoing coronary computed tomography angiography (coronary CTA).

Methods: From the multicenter CONFIRM registry, we analyzed individuals who underwent coronary CTA with known lipid-lowering therapy status and without prior coronary artery disease at baseline. Read More

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http://dx.doi.org/10.1016/j.jcct.2019.01.015DOI Listing
January 2019

ACC/AATS/AHA/ASE/ASNC/HRS/SCAI/SCCT/SCMR/STS 2019 Appropriate Use Criteria for Multimodality Imaging in the Assessment of Cardiac Structure and Function in Nonvalvular Heart Disease: A Report of the American College of Cardiology Appropriate Use Criteria Task Force, American Association for Thoracic Surgery, American Heart Association, American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society for Cardiovascular Angiography and Interventions, Society of Cardiovascular Computed Tomography, Society for Cardiovascular Magnetic Resonance, and the Society of Thoracic Surgeons.

J Am Soc Echocardiogr 2019 Feb 7. Epub 2019 Feb 7.

This document is the second of 2 companion appropriate use criteria (AUC) documents developed by the American College of Cardiology, American Association for Thoracic Surgery, American Heart Association, American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society for Cardiovascular Angiography and Interventions, Society of Cardiovascular Computed Tomography, Society for Cardiovascular Magnetic Resonance, and Society of Thoracic Surgeons. The first document addresses the evaluation and use of multimodality imaging in the diagnosis and management of valvular heart disease, whereas this document addresses this topic with regard to structural (nonvalvular) heart disease. While dealing with different subjects, the 2 documents do share a common structure and feature some clinical overlap. Read More

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http://dx.doi.org/10.1016/j.echo.2019.01.008DOI Listing
February 2019
4.056 Impact Factor

Progression of coronary atherosclerotic plaque burden and relationship with adverse cardiovascular event in asymptomatic diabetic patients.

BMC Cardiovasc Disord 2019 Feb 11;19(1):39. Epub 2019 Feb 11.

Department of Cardiology, Chinese PLA General Hospital, Beijing, People's Republic of China.

Background: The heterogeneity of risk in patients with diabetes mellitus (DM) is acknowledged in new guidelines promulgating different treatment recommendations for diabetics at low cardiac risk. We performed a retrospective longitudinal follow-up study to evaluate coronary plaque progression and its impact on cardiac events in asymptomatic diabetic patients.

Methods: Data of 197 asymptomatic patients (63. Read More

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http://dx.doi.org/10.1186/s12872-019-1016-4DOI Listing
February 2019
1 Read
1.500 Impact Factor

Rationale and design of a multicenter randomized trial to compare the graft patency between no-touch vein harvesting technique and conventional approach in coronary artery bypass graft surgery.

Am Heart J 2018 Dec 6;210:75-80. Epub 2018 Dec 6.

Department of Surgery, National Center for Cardiovascular Disease, China & Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China. Electronic address:

Background: Vein graft failure is a crucial challenge in coronary artery bypass graft (CABG) surgery. Previous studies have suggested a patency benefit of the No-Touch vein harvesting technique, but only with small sample sizes.

Materials And Methods: This study is a prospective, multicenter randomized clinical trial with a large sample size, aiming to investigate the efficacy of the No-Touch technique compared with the conventional approach. Read More

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http://dx.doi.org/10.1016/j.ahj.2018.11.011DOI Listing
December 2018
1 Read

Risk stratification in coronary artery disease: a patient-tailored approach over the ischaemic cascade.

Swiss Med Wkly 2019 Feb 11;149:w20014. Epub 2019 Feb 11.

Cardiology Department, University Hospital Basel, University of Basel, Switzerland.

Patient tailored diagnosis and risk stratification in patients with suspected or known coronary artery disease (CAD) are pivotal. At present, cardiac imaging modalities provide the possibility to evaluate the whole ischaemic cascade noninvasively. In asymptomatic patients, the evaluation of the calcium score may be beneficial and also guide the individual preventive strategy. Read More

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http://dx.doi.org/10.4414/smw.2019.20014DOI Listing
February 2019

Off-label use of Angio-Seal vascular closure device for the repair of femoral pseudoaneurysm after transfemoral coronary intervention.

J Vasc Surg Cases Innov Tech 2019 Mar 28;5(1):38-40. Epub 2019 Jan 28.

Department of Interventional Cardiology Unit, New Tokyo Hospital, Matsudo, Chiba, Japan.

Pseudoaneurysm was caused at the puncture site of the left groin after percutaneous coronary intervention. Balloon tamponade was attempted for hemostasis at the aneurysmal site. However, hemostasis was not achieved. Read More

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http://dx.doi.org/10.1016/j.jvscit.2018.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355462PMC
March 2019
5 Reads

Evaluation of ventricular septal defects using high pitch computed tomography angiography of the chest in children with complex congenital heart defects below one year of age.

J Cardiovasc Comput Tomogr 2019 Feb 1. Epub 2019 Feb 1.

University Hospital Erlangen, Department of Radiology, Maximiliansplatz 1, 91054, Erlangen, Germany; Imaging Science Institute Erlangen, Ulmenweg 18, 91054, Erlangen, Germany. Electronic address:

Background: Aim of this study was to assess the accuracy of ventricular septal defects (VSD) using high pitch computed tomography angiography (CTA) of the chest in children below 1 year of age, compared to the intraoperative findings and echocardiography.

Methods: Out of 154 patients that underwent Dual-Source CTA of the chest using a high-pitch protocol at low tube voltages (70-80 kV), 55 underwent surgical repair of a VSD (median age 8 days, range 1-348 days). The margins of the VSDs and their relation to the surrounding structures were reproduced by en-face views using multiplanar reformations (MPR). Read More

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http://dx.doi.org/10.1016/j.jcct.2019.01.023DOI Listing
February 2019

Sex differences in coronary artery plaque composition detected by coronary computed tomography: quantitative and qualitative analysis.

Neth Heart J 2019 Feb 8. Epub 2019 Feb 8.

Department of Radiology, Innsbruck Medical University, Innsbruck, Austria.

Background: Sex differences in the calculation of coronary heart disease risk have been analysed extensively. However, data on coronary plaque morphology diverge. We analysed plaque characteristics in patients with suspected coronary artery disease (CAD) and defined prognostic factors using coronary computed tomography angiography (CCTA). Read More

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http://dx.doi.org/10.1007/s12471-019-1234-5DOI Listing
February 2019
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Preclinical Evaluation of a Novel Sirolimus-Eluting Iron Bioresorbable Coronary Scaffold in Porcine Coronary Artery at 6 Months.

JACC Cardiovasc Interv 2019 Feb;12(3):245-255

Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Beijing, China. Electronic address:

Objectives: The aim of this study was to investigate the operability, 6-month efficacy, and safety of the novel sirolimus-eluting iron bioresorbable coronary scaffold (IBS) system compared with a cobalt-chromium everolimus-eluting stent (EES) (XIENCE Prime stent) in porcine coronary arteries.

Background: Bioresorbable scaffolds have been considered the fourth revolution in percutaneous coronary intervention. However, the first-generation bioresorbable scaffold showed suboptimal results. Read More

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http://dx.doi.org/10.1016/j.jcin.2018.10.020DOI Listing
February 2019
7.345 Impact Factor

Is mean heart dose a relevant surrogate parameter of left ventricle and coronary arteries exposure during breast cancer radiotherapy: a dosimetric evaluation based on individually-determined radiation dose (BACCARAT study).

Radiat Oncol 2019 Feb 7;14(1):29. Epub 2019 Feb 7.

Institut de Radioprotection et de Sureté Nucléaire (IRSN), PRP-HOM/SDOS/LEDI, Fontenay-aux-Roses, France.

Background: Intra-individual heterogeneity of cardiac exposure is an issue in breast cancer (BC) radiotherapy that was poorly considered in previous cardiotoxicity studies mainly based on mean heart dose (MHD). This dosimetric study analyzes the distribution of individually-determined radiation doses to the heart and its substructures including coronary arteries and evaluate whether MHD is a relevant surrogate parameter of dose for these substructures.

Methods: Data were collected from the BACCARAT prospective study that included left or right unilateral BC patients treated with 3D-Conformal Radiotherapy (RT) between 2015 and 2017 and followed-up for 2 years with repeated cardiac imaging examinations. Read More

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http://dx.doi.org/10.1186/s13014-019-1234-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367844PMC
February 2019
1 Read

Cost-impact of cardiac magnetic resonance imaging with Fast-SENC compared to SPECT in the diagnosis of coronary artery disease in the U.S.

J Med Econ 2019 Feb 7. Epub 2019 Feb 7.

a Avalon Health Economics , Morristown , NJ USA.

Aims: The purpose of this study is to assess the economic cost differences and the associated treatment resource changes between the developing coronary artery disease (CAD) diagnostic tool fast strain-encoded cardiac imaging (Fast-SENC) and the current commonly used stress test single-photon emission computed tomography (SPECT).

Materials And Methods: We first created a 'payer perspective' model consisting of long-term and short-term components that used a hypothetical cohort of patients of average age (60.8 years) presenting with chest pain and suspected CAD to assess cost-impact. Read More

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http://dx.doi.org/10.1080/13696998.2019.1580713DOI Listing
February 2019

Review: Acute superior mesenteric artery embolism: A vascular emergency cannot be ignored by physicians.

Medicine (Baltimore) 2019 Feb;98(6):e14446

Department of Gastroenterology.

Background: Acute mesenteric ischemia (AMI) is a life-threatening medical condition that occurs when a sudden decreased perfusion to the intestines which leads to bowel infarction, and acute superior mesenteric artery embolism (ASMAE) is the main cause of AMI. Unfortunately, with the improvement of diagnosis and treatment technology, the mortality remains high due to less frequent clinical suspicion resulted from the unclear clinical manifestation and non-specific laboratory findings.

Methods: Relevant studies published were identified by searching the PubMed, Embase and Cochrane Library databases. Read More

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http://dx.doi.org/10.1097/MD.0000000000014446DOI Listing
February 2019
1 Read

Severe acute interstitial nephritis induced by valsartan: A case report.

Medicine (Baltimore) 2019 Feb;98(6):e14428

Department of Nephrology, Tianjin Medical University General Hospital, Tianjin, China.

Rationale: Angiotensin receptor blocker (ARB) can increase serum creatinine or potassium levels in patients with renal insufficiency, renal artery stenosis, heart failure or hypovolemia, but hardly cause severe kidney injury in patients without any risk factors. A case of severe acute interstitial nephritis (AIN) induced by valsartan was reported here.

Patient Concerns: A 62-year-old female with nausea for 1 month and acute deterioration of kidney function for 2 weeks was admitted. Read More

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http://dx.doi.org/10.1097/MD.0000000000014428DOI Listing
February 2019
1 Read
5.723 Impact Factor

In vitro optimization and comparison of CT angiography versus radial cardiovascular magnetic resonance for the quantification of cross-sectional areas and coronary endothelial function.

J Cardiovasc Magn Reson 2019 Feb 7;21(1):11. Epub 2019 Feb 7.

Department of Diagnostic and Interventional Radiology, Lausanne University Hospital (CHUV and UNIL), Rue du Bugnon 46, Lausanne, 1011, VD, Switzerland.

Background: Our objectives were first to determine the optimal coronary computed tomography angiography (CTA) protocol for the quantification and detection of simulated coronary artery cross-sectional area (CSA) differences in vitro, and secondly to quantitatively compare the performance of the optimized CTA protocol with a previously validated radial coronary cardiovascular magnetic resonance (CMR) technique.

Methods: 256-multidetector CTA and radial coronary CMR were used to obtain images of a custom in vitro resolution phantom simulating a range of physiological responses of coronary arteries to stress. CSAs were automatically quantified and compared with known nominal values to determine the accuracy, precision, signal-to-noise ratio (SNR), and circularity of CSA measurements, as well as the limit of detection (LOD) of CSA differences. Read More

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http://dx.doi.org/10.1186/s12968-019-0521-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366062PMC
February 2019

Patients with Acute Ischemic Cerebrovascular Disease with Coronary Artery Stenosis Have More Diffused Cervicocephalic Atherosclerosis.

J Atheroscler Thromb 2019 Feb 6. Epub 2019 Feb 6.

Department of Radiology, Xuanwu Hospital, Capital Medical University.

Aim: Coronary artery stenosis (CAS) ≥ 50% frequently coexists in patients with acute ischemic cerebrovascular disease (AICVD), which portends unfavorable outcomes. We sought to examine whether patients with AICVD with CAS had more severe and more diffused cervicocephalic atherosclerosis (CA).

Methods: Patients with AICVD were consecutively enrolled and underwent simultaneous computed tomography angiography (CTA) of the coronary and cervicocephalic arteries. Read More

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https://www.jstage.jst.go.jp/article/jat/advpub/0/advpub_474
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http://dx.doi.org/10.5551/jat.47464DOI Listing
February 2019
2 Reads

Comprehensive coronary plaque assessment in patients with obstructive sleep apnea.

J Sleep Res 2019 Feb 6:e12828. Epub 2019 Feb 6.

Cardiovascular Imaging Research Group, Heart and Vascular Center, Semmelweis University, Budapest, Hungary.

Obstructive sleep apnea (OSA) is associated with an increased risk of cardiovascular disease. Previous studies have assessed the relationship between OSA and coronary artery disease (CAD) using coronary artery calcium score (CAC) measurements. However, limited data are available regarding the association of OSA with non-calcified plaque burden. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/jsr.12828
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http://dx.doi.org/10.1111/jsr.12828DOI Listing
February 2019
3 Reads

Spontaneous Coronary Artery Dissection Masquerading as Coronary Artery Stenosis in a Young Patient.

Am J Case Rep 2019 Feb 6;20:159-162. Epub 2019 Feb 6.

Department of Cardiology, Rapides Regional Medical Center, Alexandria, LA, USA.

BACKGROUND Spontaneous coronary artery dissection (SCAD) is primarily found in females. SCAD can have many precipitating factors such as exercise, trauma, pregnancy, drugs, and connective tissue disease. Prognosis is poor for left main stem, left anterior descending (LAD) artery, and multivessel involvement, especially for females. Read More

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http://dx.doi.org/10.12659/AJCR.913522DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375282PMC
February 2019
2 Reads

Predicting the Physiological Effect of Revascularization in Serially Diseased Coronary Arteries.

Circ Cardiovasc Interv 2019 Feb;12(2):e007577

NIHR Biomedical Research Centre and British Heart Foundation Centre of Excellence, School of Cardiovascular Medicine and Sciences, King's College London (B.N.M., H.E., R.R., D.P.).

Background: Fractional flow reserve (FFR) is commonly used to assess the functional significance of coronary artery disease but is theoretically limited in evaluating individual stenoses in serially diseased vessels. We sought to characterize the accuracy of assessing individual stenoses in serial disease using invasive FFR pullback and the noninvasive equivalent, fractional flow reserve by computed tomography (FFR). We subsequently describe and test the accuracy of a novel noninvasive FFR-derived percutaneous coronary intervention (PCI) planning tool (FFR) in predicting the true significance of individual stenoses. Read More

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https://www.ahajournals.org/doi/10.1161/CIRCINTERVENTIONS.11
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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.118.007577DOI Listing
February 2019
3 Reads

Coronary artery plaque characteristics and treatment with biologic therapy in severe psoriasis: results from a prospective observational study.

Cardiovasc Res 2019 Feb 5. Epub 2019 Feb 5.

Section of Inflammation and Cardiometabolic Disease, National Heart, Lung, and Blood Institute; National Institutes of Health, Bethesda, MD, USA.

Aims: The use of biologic therapy has increased over the past decade well beyond primary autoimmune diseases. Indeed, a recent trial using an anti-IL-1beta antibody reduced second myocardial infarction (MI) in those who have had MI. Psoriasis is a chronic inflammatory disease often treated with biologics when severe, is associated with increased risk of MI, in part driven by high-risk coronary plaque phenotypes by coronary computed tomography angiography (CCTA). Read More

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http://dx.doi.org/10.1093/cvr/cvz009DOI Listing
February 2019
1 Read

Infra-renal vs supra-renal abdominal aortic aneurysms: Comparison of associated aneurysms and renal artery stenosis.

Ann Vasc Surg 2019 Feb 2. Epub 2019 Feb 2.

Department of Intensive Care and Perioperative Medicine, Jagiellonian University Medical College, ul. Skawińska 8, 31-066 Kraków, Poland. Electronic address:

Objective: The aim of our study was to assess the prevalence of concomitant arterial abnormalities (true aneurysms of iliac, common femoral, renal, visceral arteries and stenoses of iliac and renal arteries) in patients with abdominal aortic aneurysm, and to evaluate whether the type of the aneurysm (suprarenal versus solely infrarenal) is associated with this prevalence.

Methods: In this retrospective cross-sectional study we assessed computed tomography angiography scans of 933 patients with abdominal aortic aneurysm, including thoraco-abdominal aortic aneurysms type II-IV, with no history of abdominal aortic surgery. We compared two groups of patients: group 1 (n=859) with solely infrarenal abdominal aortic aneurysm and group 2 (n=74) with the suprarenal aneurysm component. Read More

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http://dx.doi.org/10.1016/j.avsg.2018.10.044DOI Listing
February 2019
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Surgical Treatment of Proximal Segmental Occlusion of the Internal Carotid Artery.

Surg Res Pract 2019 2;2019:2976091. Epub 2019 Jan 2.

Department of Vascular Surgery, Institute for Cardiovascular Disease "Dedinje", Belgrade, Serbia.

Purpose: To present the feasibility, safety, and efficacy of carotid endarterectomy in patients with type II internal carotid artery occlusions, including the long-term outcomes.

Methods: From March 2008 to August 2015, 74 consecutive patients (48 men with a mean age of 65.1 ± 8. Read More

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http://dx.doi.org/10.1155/2019/2976091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334308PMC
January 2019
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Diagnostic accuracy of low-radiation coronary computed tomography angiography with low tube voltage and knowledge-based model reconstruction.

Sci Rep 2019 Feb 4;9(1):1308. Epub 2019 Feb 4.

Department of Radiology and Research Institute of Radiological Science, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.

We aimed to evaluate the accuracy of coronary computed tomography angiography (CCTA) with a low-radiation protocol and iterative model reconstruction (IMR), in comparison with invasive coronary angiography (ICA). Sixty-one patients (45 males; mean age, 61.9 ± 9. Read More

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http://dx.doi.org/10.1038/s41598-018-37870-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362232PMC
February 2019
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Volumes of coronary plaque disease in relation to body mass index, waist circumference, truncal fat mass and epicardial adipose tissue in patients with type 2 diabetes mellitus and controls.

Diab Vasc Dis Res 2019 Feb 3:1479164119825761. Epub 2019 Feb 3.

1 Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark.

Objectives:: Coronary atherosclerosis in patients with type 2 diabetes mellitus may be promoted by regional fat distribution. We investigated the association between anthropometric measures of obesity, truncal fat mass, epicardial adipose tissue and coronary atherosclerosis in asymptomatic patients and matched controls.

Methods:: We examined 44 patients and 59 controls [mean (standard deviation) age 64. Read More

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http://dx.doi.org/10.1177/1479164119825761DOI Listing
February 2019

A rare coronary anomaly -- type 4 dual left anterior descending artery accompanying anomalous origin of the left coronary artery from the right coronary sinus.

J Cardiovasc Comput Tomogr 2019 Jan 26. Epub 2019 Jan 26.

Department of Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan; Department of Radiology, National Taiwan University College of Medicine, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.jcct.2019.01.019DOI Listing
January 2019

Difficulties of Diagnostics of Obstructive Coronary Artery Lesions in Patients with Stable Ischemic Heart Disease and Possibilities of Single-Photon Emission Computed Tomography.

Kardiologiia 2019 Jan 27;59(1):28-35. Epub 2019 Jan 27.

Research Institute for Complex Issues of Cardiovascular Disease.

Purpose: to assess diagnostic capabilities of single-photon emission computed tomography (SPECT) in the detection of obstructive coronary artery (CA) lesions, depending on the meeting appropriate use criteria.

Materials And Methods: We used in this retrospective analysis data from 107 patients with previously diagnosed ischemic heart disease (IHD) or in need to exclude it, who were hospitalized in inpatient departments of the Research Institute for Complex Issues of Cardiovascular Diseases in the period from 2012 to 2015. All patients underwent coronary angiography (CAG) and SPECT (the time interval between the studies did not exceed 3 months) for detection of hemodynamically significant CA stenoses. Read More

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https://lib.ossn.ru/jour/article/view/427
Publisher Site
http://dx.doi.org/10.18087/cardio.2019.1.10226DOI Listing
January 2019
3 Reads

An acute stroke CT imaging algorithm incorporating automated perfusion analysis.

Emerg Radiol 2019 Feb 1. Epub 2019 Feb 1.

Department of Radiology, Mater Misericordiae University Hospital, Whitty Building, North Circular Road, Dublin 7, Ireland.

In this paper, we propose a CT imaging algorithm for patients presenting with suspected acute stroke that incorporates automated CT perfusion (CTP) imaging. The algorithm details evaluation of the non-contrast CT (NCCT) for hemorrhage and acute ischemia, calculation of ASPECTS, with performance and interpretation of CTP if appropriate. In particular, we consider the key steps in expeditious interpretation of non-contrast CT and CT angiography in the context of suspected acute ischemic stroke. Read More

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http://dx.doi.org/10.1007/s10140-019-01675-2DOI Listing
February 2019

A functional evaluation of cerebral perfusion for coronary artery bypass grafting patients.

Heart Vessels 2019 Jan 31. Epub 2019 Jan 31.

Division of Cardiac Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan.

We evaluate the utility of providing a pulsatile blood flow by applying off-pump coronary artery bypass grafting (CABG) or intra-aortic balloon pumping (IABP) with conventional CABG to prevent perioperative stroke in patients with cerebral hypoperfusion on single-photon emission-computed tomography (SPECT). A total of 286 patients underwent isolated CABG with a cerebral magnetic resonance angiography (MRA) evaluation between 2006 and 2015. Seventy-five had significant stenosis and/or occlusion of craniocervical vessels; the other 211 had no significant stenosis. Read More

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http://dx.doi.org/10.1007/s00380-019-01348-7DOI Listing
January 2019
2 Reads