25,128 results match your criteria Coronary CT Angiography

Fibromuscular dysplasia: its various phenotypes in everyday practice in 2021.

Kardiol Pol 2021 Jun 24. Epub 2021 Jun 24.

Pole of Cardiovascular Research, Institut de Recherche Expérimentale et Clinique and Division of Cardiology, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium.

Fibromuscular dysplasia (FMD) is a non-atherosclerotic vascular disease that may involve medium-sized muscular arteries throughout the body. The pathogenesis of FMD remains poorly understood, but a combination of genetic and environmental factors may be involved. The majority of FMD patients are women, but men may have a more progressive disease, especially when smoking. Read More

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Aortic enlargement and coronary artery calcification in a general population cohort.

Eur Heart J Cardiovasc Imaging 2021 Jun 24. Epub 2021 Jun 24.

Department of Cardiology, The Heart Center, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, 2100Copenhagen, Denmark.

Aims: The role of atherosclerosis in the pathogenesis of aortic enlargement is uncertain. We aimed to evaluate the relationship between the diameters of the ascending, descending and abdominal aorta, and coronary artery calcification.

Methods And Results: Individuals in the Copenhagen General Population Study underwent thoracic and abdominal computed tomography. Read More

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Myopericarditis in children and adolescent: is the elevated troponin and chest pain as alarming as we thought?

Cardiol Young 2021 Jun 21:1-5. Epub 2021 Jun 21.

Department of Pediatric Cardiology, Marmara University, İstanbul, Turkey.

Aim: When encountering adolescents with chest pain and a high troponin level but with no underlying coronary artery illness, it is advisable to consider myopericarditis. Though myopericarditis is a self-limiting, benign condition, it nevertheless causes anxiety in the patient and the family.

Methods: Thirty-nine patients diagnosed with myopericarditis were included. Read More

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SIRM-SIC appropriateness criteria for the use of Cardiac Computed Tomography. Part 1: Congenital heart diseases, primary prevention, risk assessment before surgery, suspected CAD in symptomatic patients, plaque and epicardial adipose tissue characterization, and functional assessment of stenosis.

Radiol Med 2021 Jun 23. Epub 2021 Jun 23.

Cardiothoracovascular Department, Azienda Ospedaliero Universitaria Careggi, Florence, Italy.

In the past 20 years, Cardiac Computed Tomography (CCT) has become a pivotal technique for the noninvasive diagnostic work-up of coronary and cardiac diseases. Continuous technical and methodological improvements, combined with fast growing scientific evidence, have progressively expanded the clinical role of CCT. Recent large multicenter randomized clinical trials documented the high prognostic value of CCT and its capability to increase the cost-effectiveness of the management of patients with suspected CAD. Read More

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Quantification of myocardial ischemia and subtended myocardial mass at adenosine stress cardiac computed tomography: a feasibility study.

Int J Cardiovasc Imaging 2021 Jun 23. Epub 2021 Jun 23.

Department of Cardiology, Leiden Heart-Lung Center, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, Netherlands.

Combination of coronary computed tomography angiography (CCTA) and adenosine stress CT myocardial perfusion (CTP) allows for coronary artery lesion assessment as well as myocardial ischemia. However, myocardial ischemia on CTP is nowadays assessed semi-quantitatively by visual analysis. The aim of this study was to fully quantify myocardial ischemia and the subtended myocardial mass on CTP. Read More

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Twelve-month Outcomes of the LuX-Valve for Transcatheter Treatment of Severe Tricuspid Regurgitation.

EuroIntervention 2021 Jun 23. Epub 2021 Jun 23.

Department of Ultrasound, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan, China.

Background: Severe functional tricuspid regurgitation is associated with adverse clinical outcomes. Conventional surgical risk for patients with advanced tricuspid regurgitation stage is high, alternative approaches are therefore required.

Aims: The purpose of this study was to investigate the feasibility, technical details, and mid-term outcomes of implantation of a novel radial force-independent orthotopic transcatheter tricuspid valve-LuX-Valve in patients with severe functional tricuspid regurgitation. Read More

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KLF2 Mediates the Suppressive Effect of Laminar Flow on Vascular Calcification by Inhibiting Endothelial BMP/SMAD1/5 Signaling.

Circ Res 2021 Jun 23. Epub 2021 Jun 23.

School of Biomedical Sciences, The Chinese University of Hong Kong, CHINA.

Vascular calcification in arterial intima is closely associated with atherosclerosis. Endothelial cells (ECs) sense blood flow and respond to the mechanical cues generated by different flow patterns. Laminar flow (LF) induces an anti-atherosclerotic EC phenotype whereas disturbed flow (DF) exerts an atheroprone effect. Read More

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Predictive ability of coronary computed tomography angiography parameters in patients suspected of obstructive coronary artery disease: a single-center cross-sectional study.

Eur Rev Med Pharmacol Sci 2021 Jun;25(11):4074-4085

Department of Internal Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.

Objective: Coronary computed tomography angiography (CCTA) is becoming increasingly useful for the diagnosis of coronary artery disease (CAD). Coronary calcium score (CCS), epicardial fat volume (EFV), and number of coronary plaques (NoP) add important information for the risk stratification and prognosis prediction of these patients. However, evidence about their ability to predict obstructive CAD is limited. Read More

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Variation of computed tomographic angiography-based fractional flow reserve after transcatheter aortic valve implantation.

Eur Radiol 2021 Jun 22. Epub 2021 Jun 22.

Department of Cardiology, West China Hospital, Sichuan University, #37 Guo Xue Alley, Chengdu, 610041, China.

Objectives: We sought to identify the impact of transcatheter aortic valve implantation (TAVI) on changes of fractional flow reserve computed tomography (FFR) values and the associated clinical impact.

Methods: A retrospective analysis was done with CT obtained pre-TAVI, prior to hospital discharge and at 1-year follow-up, which provided imaging sources for the calculation of FFR values based on an online platform.

Results: A total of 190 patients were enrolled. Read More

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Predicting reintervention after thoracic endovascular aortic repair of Stanford type B aortic dissection using machine learning.

Eur Radiol 2021 Jun 22. Epub 2021 Jun 22.

Department of Catheterization Lab, Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of South China Structural Heart Disease, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, No. 106 Zhongshan Er Road, Guangzhou, 510080, People's Republic of China.

Objectives: To construct models for predicting reintervention after thoracic endovascular aortic repair (TEVAR) of Stanford type B aortic dissection (TBAD).

Methods: A total of 192 TBAD patients who underwent TEVAR were included; 68 (35.4%) had indications for reintervention. Read More

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Anomalous origin of coronary artery from the opposite aortic sinus of Valsalva-a single center experience with a therapeutic conundrum.

Indian Heart J 2021 May-Jun;73(3):289-294. Epub 2021 Apr 3.

Department of Cardiology, Seth G.S. Medical College & King Edward Memorial Hospital, Mumbai, India.

Background: Coronary artery anomalies are rare congenital abnormalities, most often found incidentally on conventional coronary angiography and CT angiography (CTA). CTA better delineates the origin and course of anomalous coronaries. Anomalous origin of coronary artery from the opposite aortic sinus of Valsalva (ACAOS) has a prevalence of 1% with a very few having an interarterial (malignant) course. Read More

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Endovascular Repair of Postdissection Thoracoabdominal Aortic Aneurysm in Patients With Vascular Ehlers-Danlos Syndrome.

J Endovasc Ther 2021 Jun 21:15266028211025038. Epub 2021 Jun 21.

German Aortic Center, University Heart Center, University Hospital Hamburg-Eppendorf, Hamburg, Germany.

Purpose: To report endovascular repair of postdissection thoracoabdominal aortic aneurysm (TAAA) in 2 patients with vascular Ehlers-Danlos syndrome (vEDS).

Case Reports: . A 56-year-old vEDS male patient with a 50-mm type III TAAA [history of aortic root repair, hemiarch replacement, and thoracic endovascular aortic repair (TEVAR) for acute type A aortic dissection (TAAD) 7 years ago] was treated by a 2-stage procedure; first, cervical debranching of the left subclavian artery and second TEVAR and t-branch. Read More

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Risk predicting for acute coronary syndrome based on machine learning model with kinetic plaque features from serial coronary computed tomography angiography.

Eur Heart J Cardiovasc Imaging 2021 Jun 21. Epub 2021 Jun 21.

Department of Geriatric Cardiology & National Clinical Research Center for Geriatric Diseases, Second Medical Center of Chinese PLA General Hospital, 28# Fuxing road, Haidian district, Beijing 100853, China.

Aims: More patients with suspected coronary artery disease underwent coronary computed tomography angiography (CCTA) as gatekeeper. However, the prospective relation of plaque features to acute coronary syndrome (ACS) events has not been previously explored.

Methods And Results: One hundred and one out of 452 patients with documented ACS event and received more than once CCTA during the past 12 years were recruited. Read More

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Myocardial Flow Reserve Measurement During CZT-SPECT Perfusion Imaging for Coronary Artery Disease Screening: Correlation With Clinical Findings and Invasive Coronary Angiography-The CFR-OR Study.

Front Med (Lausanne) 2021 4;8:691893. Epub 2021 Jun 4.

Nuclear Medicine Department, CHRU TOURS, Tours, France.

The aim of this study was to assess the results of cadmium zinc telluride (CZT)- single-photon emission computed tomography (SPECT) myocardial flow reserve (MFR) in coronary artery disease (CAD) screening regarding clinical risk and its correlation to invasive coronary angiography (ICA). A total of 137 patients (61 male and 76 female) referred for CAD screening myocardial perfusion imaging (MPI) between November 2018 and April 2020 were included in the CFR-OR prospective trial. The 10-year risk of cardiovascular death according to the European Society of Cardiology (SCORE) was calculated. Read More

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The value of coronary CTA in the diagnosis of coronary artery disease.

Am J Transl Res 2021 15;13(5):5287-5293. Epub 2021 May 15.

Department of Radiology, Affiliated People's Hospital of Ningbo University Ningbo, Zhejiang Province, China.

Objective: To investigate the diagnostic value of coronary computed tomography angiography (CTA) in the detection of coronary artery disease.

Methods: From January 2017 to December 2019, 150 patients with suspected coronary artery disease admitted to the Affiliated People's Hospital of Ningbo University were recruited as the research cohort for this study. All the patients underwent a coronary CTA and a coronary angiography. Read More

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Coronary artery calcium score above 250 confirms the presence of significant stenosis in coronary CT angiography of symptomatic patients.

Coron Artery Dis 2021 Jun 18. Epub 2021 Jun 18.

Department of Radiology, College of Medicine, King Khalid University, Saudi Arabia.

Objectives: Evaluation of coronary artery calcium score (CACS) at multiple low and high cutoff values for the detection of significant coronary stenosis at two different cutoffs (50 and 70%) in a large number of symptomatic patients was not investigated previously in one study. This study aims to investigate if there are a correlation and statistical significance between different CACS cutoffs and the severity of coronary artery stenosis by coronary CT angiography (CCTA) in symptomatic patients.

Methods: This is a retrospective study that included all symptomatic patients who had CCTA in a tertiary care hospital over a period of 7 years. Read More

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Preprocedural Coronary CT Angiography Effect on the Likelihood to Restore Flow in Chronic Total Occlusion.

JACC Cardiovasc Imaging 2021 Jun 10. Epub 2021 Jun 10.

Heart Institute at the Edith Wolfson Medical Center, Holon, Israel; Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

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Interplay of Risk Factors and Coronary Artery Calcium for CHD Risk in Young Patients.

JACC Cardiovasc Imaging 2021 Jun 16. Epub 2021 Jun 16.

Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark.

Objectives: The aim of this study was to examine prevalence, predictors, and impact of coronary artery calcium (CAC) across different risk factor burdens on the prevalence of obstructive coronary artery disease (CAD) and future coronary heart disease (CHD) risk in young patients.

Background: The interplay of risk factors and CAC for predicting CHD in young patients aged ≤45 years is not clear.

Methods: The study included 3,691 symptomatic patients (18-45 years of age) from the WDHR (Western Denmark Heart Registry) undergoing coronary computed tomographic angiography. Read More

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Effect of Coronary CTA on Chronic Total Occlusion Percutaneous Coronary Intervention: A Randomized Trial.

JACC Cardiovasc Imaging 2021 Jun 9. Epub 2021 Jun 9.

Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, South Korea. Electronic address:

Objectives: The purpose of this study was to test whether the success rate of percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) increased with pre-procedural coronary computed tomography angiography (CTA).

Background: Coronary CTA provides valuable information before and during CTO-PCI. However, there are no randomized data that explore whether coronary CTA increases its success rate. Read More

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Prediction and Prevention of Cardiovascular Events Through Quantitative Coronary Plaque Burden Assessment in Women.

Maros Ferencik

JACC Cardiovasc Imaging 2021 Jun 9. Epub 2021 Jun 9.

Knight Cardiovascular Institute, Oregon Health and Science University, Portland, Oregon, USA; Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA; Cardiovascular Imaging Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA. Electronic address:

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Giant coronary artery aneurysms involving more than one coronary artery: case report.

J Cardiothorac Surg 2021 Jun 19;16(1):177. Epub 2021 Jun 19.

Division of Cardiothoracic Surgery, Advent Health, Orlando, Florida, USA.

Background: Coronary artery aneurysms are rare findings in patients undergoing coronary angiography. The presence of multiple coronary artery aneurysms located in more than one coronary artery is even more uncommon. The pathophysiology of such aneurysms is unknown, but the majority are often due to atherosclerosis, congenital heart disease, or vasculitis. Read More

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Is There a Role of Coronary CTA in Primary Prevention? Current State and Future Directions.

Curr Atheroscler Rep 2021 Jun 19;23(8):44. Epub 2021 Jun 19.

Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, MD, USA.

Purpose Of Review: Information on subclinical atherosclerosis burden provides prognostic information on atherosclerotic cardiovascular disease (ASCVD) risk beyond what can be achieved by traditional risk factors alone and may therefore improve allocation of preventive treatment in primary prevention. The purpose of this review is to discuss the potential role and value of assessing subclinical atherosclerosis using coronary artery calcium (CAC) versus computed tomography angiography (CTA) among asymptomatic patients in the context of current primary prevention cholesterol guidelines.

Recent Findings: Since 2013, primary prevention cholesterol guidelines have lowered the treatment threshold for initiating statin therapy resulting in high statin eligibility and sensitivity for detecting ASCVD events. Read More

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Lipid biomarkers in statin users with coronary artery disease annotated by coronary computed tomography angiography.

Sci Rep 2021 Jun 18;11(1):12899. Epub 2021 Jun 18.

Istituto di Fisiologia Clinica-CNR, via Giuseppe Moruzzi 1, 56124, Pisa, Italy.

Molecular markers are suggested to improve the diagnostic and prognostic accuracy in patients with coronary artery disease (CAD) beyond current clinical scores based on age, gender, symptoms and traditional risk factors. In this context, plasma lipids are emerging as predictors of both plaque composition and risk of future events. We aim to identify plasma lipid biomarkers associated to CAD indexes of stenosis severity, plaque lipid content and a comprensive score of CAD extent and its risk. Read More

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Extensive and balanced reduction of myocardial blood flow in patients with suspected obstructive coronary artery disease: 15O-water PET study.

Int J Cardiol 2021 Jun 15. Epub 2021 Jun 15.

Turku PET Centre, University of Turku, Turku, Finland; Department of Clinical Physiology, Nuclear Medicine and PET, Turku University Hospital, Turku, Finland.

Background: Detection of obstructive coronary artery disease (CAD) by stress myocardial perfusion imaging (MPI) is conventionally based on relative differences in perfusion. This may lead to either underestimation of the extent of myocardial ischemia, or the ischemia might be completely missed in case of balanced perfusion reduction. Using absolute quantification of myocardial blood flow (MBF) by positron emission tomography (PET), we evaluated how common are extensive and balanced myocardial perfusion abnormalities in symptomatic patients with suspected obstructive CAD. Read More

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Prevalence of Peripheral Arterial Disease in Diabetic Foot Ulcer Patients and its Impact in Limb Salvage.

Int J Low Extrem Wounds 2021 Jun 18:15347346211027063. Epub 2021 Jun 18.

68780Mansoura University, Egypt.

Diabetic foot ulcer syndrome is a common complication of diabetes mellitus. Three main factors contribute to it: neuropathy, vasculopathy, and infection. This study was conducted to evaluate the prevalence of peripheral arterial disease (PAD) in diabetic foot ulcer patients and its impact on limb salvage as an outcome. Read More

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Subtraction improves the accuracy of coronary CT angiography for detecting obstructive disease in severely calcified segments.

Eur Radiol 2021 Jun 17. Epub 2021 Jun 17.

Department of Radiology, Beijing Friendship Hospital, Capital Medical University, No. 95 YongAn Road, Beijing, 100050, People's Republic of China.

Objective: To investigate the accuracy, diagnostic confidence, and interobserver agreement of subtraction coronary CT angiography (CCTA) versus invasive coronary angiography on 320-row CT in coronary segments with severe or non-severe calcification.

Materials/methods: Sixty-four patients (33 men, 66.6 ± 8. Read More

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Left atrial function by cardiac computed tomography is a predictor of heart failure and cardiovascular death.

Eur Radiol 2021 Jun 16. Epub 2021 Jun 16.

Cardiology Department, Rambam Health Care Campus, Haaliya Street, 31096, Haifa, Israel.

Objectives: We sought to evaluate cardiac CT angiography (CCTA)-based assessment of left atrial (LA) function as a predictor of hospitalizations for heart failure (HF) and cardiovascular (CV) mortality.

Methods: LA function was evaluated using automatic derivation of LA volumes to calculate LA total emptying fraction (LATEF) in 788 consecutive patients with normal sinus rhythm who had undergone spiral CT scans. The relationship between LATEF evaluated by CCTA and the composite endpoint of admission for HF or CV mortality was analyzed using Cox models. Read More

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Coronary Artery Calcification as a Marker for Coronary Artery Stenosis: Comparing Kidney Failure to the General Population.

Kidney Med 2021 May-Jun;3(3):386-394.e1. Epub 2021 Apr 20.

Department of Nephrology, Amsterdam UMC, Amsterdam Cardiovascular Sciences, Amsterdam.

Rationale & Objective: The presence of calcified plaques in the coronary arteries is associated with cardiovascular mortality and is a hallmark of chronic kidney failure, but it is unclear whether this is associated with the same degree of coronary artery stenosis as in patients without kidney disease. We compared the relationship of coronary artery calcification (CAC) and stenosis between dialysis patients and patients without chronic kidney disease (CKD).

Study Design: Observational cohort study. Read More

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