1,636,144 results match your criteria Coronary CT Angiography


Accuracy of Prenatal Diagnosis of Congenital Cardiac MalformationsAcurácia do diagnóstico pré-natal de cardiopatias congênitas.

Rev Bras Ginecol Obstet 2018 Dec 14. Epub 2018 Dec 14.

Department of Postgraduate Program and Obstetrics and Gynecology, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS, Brazil.

Objective:  To evaluate the accuracy of the diagnosis of fetal heart diseases obtained through ultrasound examinations performed during the prenatal period compared with the postnatal evaluation.

Methods:  A retrospective cohort study with 96 pregnant women who were attended at the Echocardiography Service and whose deliveries occurred at the Complexo Hospitalar Santa Casa de Porto Alegre, in the state of Rio Grande do Sul, Brazil. Risk factor assessment plus sensitivity and specificity analysis were used, comparing the accuracy of the screening for congenital heart disease by means of obstetrical ultrasound and morphological evaluation and fetal echocardiography, considering  < 0. Read More

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December 2018

Novel endotypes in heart failure: effects on guideline-directed medical therapy.

Eur Heart J 2018 Dec 13. Epub 2018 Dec 13.

Department of Cardiology, University of Groningen, Hanzeplein 1, Groningen, the Netherlands.

Aims: We sought to determine subtypes of patients with heart failure (HF) with a distinct clinical profile and treatment response, using a wide range of biomarkers from various pathophysiological domains.

Methods And Results: We performed unsupervised cluster analysis using 92 established cardiovascular biomarkers to identify mutually exclusive subgroups (endotypes) of 1802 patients with HF and reduced ejection fraction (HFrEF) from the BIOSTAT-CHF project. We validated our findings in an independent cohort of 813 patients. Read More

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December 2018

Social and early life adversity and chronic health conditions among Tunisian adults.

Transl Behav Med 2018 Dec 13. Epub 2018 Dec 13.

Duluth Medical Research Institute, University of Minnesota, Duluth, MN, USA.

Early life adversities (ELAs) are shown as significant risk factors for chronic health conditions (CHCs). ELAs include multiple types of abuse such as the social abuse (peer, community, and collective violence). The purpose is to describe the relationship between childhood social abuse and chronic conditions in adulthood among a sample of adults in Tunisia and to investigate the role of obesity and tobacco use as mediators of this association. Read More

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December 2018
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Appropriate use criteria adoption for PCI at an academic medical center.

Eur Heart J 2018 Dec;39(47):4136-4138

Division of Cardiovascular Medicine, Department of Medicine, Case Western Reserve University School of Medicine, 11100 Euclid Ave, Mailstop LKS 5038, Cleveland, Ohio, Phone: (216) 844-7760, Fax: (216) 844-8954.

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December 2018

FIFA World Cup 2018.

Eur Heart J 2018 Dec;39(47):4139-4142

Department of Medicine I, University Hospital Munich, Ludwig Maximilian University, Campus Innenstadt, Ziemssenstrasse 1, Munich, Germany.

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December 2018

Arterial and pulmonary hypertension: risk assessment and current pharmacological and interventional management.

Eur Heart J 2018 Dec;39(47):4127-4131

Imperial College and Consultant and Director of Research, Education & Development, Royal Brompton and Harefield Hospital Trust, London, UK.

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December 2018

Named lectures at ESC Congress 2018.

Authors:

Eur Heart J 2018 Dec;39(47):4132-4136

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December 2018

Professor Sanjay Sharma FESC.

Authors:

Eur Heart J 2018 Dec;39(47):4143

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December 2018

A tick beat in the electrocardiogram: Persistent third degree block as only manifestation of Lyme disease.

J Electrocardiol 2018 Dec 6;52:109-111. Epub 2018 Dec 6.

Internal Medicine Department, Hospital Universitario, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico.

Lyme disease is the most common tick-borne illness in North America. A 23-year-old female presented to our emergency department with a chief complaint of sudden dyspnea and chest pain. An electrocardiogram revealed a third degree heart block. Read More

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December 2018

Recombinant human interleukin-1 receptor antagonist treatment protects rats from myocardial ischemia-reperfusion injury.

Biomed Pharmacother 2018 Dec 11;111:1-5. Epub 2018 Dec 11.

Department of Cardiology, Rui Jin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 20025, PR China. Electronic address:

The interleukin-1 (IL-1) signaling pathway plays a vital role in multiple mechanisms associated with myocardial ischemia-reperfusion (I/R) injury, including inflammation and apoptosis. An IL-1 receptor antagonist (IL-1Ra) can block IL-1 by competitive binding to the IL-1 receptor type I (IL-1RI) and thus may provide a cardioprotective effect. In the present investigation, we determined whether exogenous administration of recombinant human IL-1Ra (rhIL-1Ra) provides a protective role against myocardial I/R injury. Read More

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December 2018

Stromal PTEN Regulates Extracellular Matrix Organization in the Mammary Gland.

Neoplasia 2018 Dec 11;21(1):132-145. Epub 2018 Dec 11.

Department of Biomedical Engineering, College of Engineering, The Ohio State University, Columbus, OH 43210; The James Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210. Electronic address:

The organization of the extracellular matrix has a profound impact on cancer development and progression. The matrix becomes aligned throughout tumor progression, providing "highways" for tumor cell invasion. Aligned matrix is associated with breast density and is a negative prognostic factor in several cancers; however, the underlying mechanisms regulating this reorganization remain poorly understood. Read More

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December 2018
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A New Model to Predict Ischemic Stroke in Patients with Atrial Fibrillation Using Warfarin or Direct Oral Anticoagulants.

Heart Rhythm 2018 Dec 11. Epub 2018 Dec 11.

Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA.

Background: Stroke risk stratification scores (e.g., CHADS-VASc) are used to tailor therapeutic recommendations for patients with atrial fibrillation (AF) in different risk groups. Read More

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December 2018
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Differences in the Upslope of the Precordial Body Surface ECG T-Wave Reflect Right To Left Dispersion of Repolarization in the Intact Human Heart.

Heart Rhythm 2018 Dec 11. Epub 2018 Dec 11.

Department of Cardiac Electrophysiology, The Barts Heart Center, St Bartholomew's Hospital, London, UK; Institute of Cardiovascular Science, University College London, London, UK.

Background: The relationship between the surface ECG T-wave to intracardiac repolarization is poorly understood.

Objectives: This study aimed to examine the association between intracardiac ventricular repolarization and the T-wave on the body surface ECG (SECG).

Methods: 10 normal heart patients (age 35 +/- 15yrs, 6Male), were studied. Read More

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December 2018

Hemodynamic consequences of premature ventricular contractions Association of mechanical bradycardia and post-extrasystolic potentiation with premature ventricular contraction-induced cardiomyopathy.

Heart Rhythm 2018 Dec 11. Epub 2018 Dec 11.

University Hospital Rangueil, Toulouse, France; Unité Inserm U 1048, Toulouse, France. Electronic address:

Background: relationships between hemodynamic consequences of premature ventricular contractions (PVCs) and development of PVC-induced cardiomyopathy (PVC-CM) have not been investigated so far.

Objective: to correlate concealed mechanical bradycardia and/or post-extrasystolic potentiation (PEP) to PVC-CM.

Methods: Invasive arterial pressure from 17 patients with PVC-CM and 16 controls with frequent PVCs were retrospectively analyzed. Read More

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December 2018

Safety and Feasibility of a Mid-Septal Implantation Technique of A Leadless Pacemaker.

Heart Rhythm 2018 Dec 11. Epub 2018 Dec 11.

Cardiology Division, Department of Medicine, Queen Mary Hospital, the University of Hong Kong, Hong Kong SAR, China;; Division of Cardiology, Department of Medicine, the University of Hong Kong Shenzhen Hospital, China;; Shenzhen Institutes of Research and Innovation, University of Hong Kong, China. Electronic address:

Background: The major risk of implanting leadless pacemaker at the right ventricular apex is cardiac perforation.

Objective: We described and prospectively evaluated the safety and feasibility of a technique for mid-septal implantation of the Micra leadless pacemaker.

Methods: We positioning the device at the center of the cardiac silhouette in the right anterior oblique (RAO) view, towards the left in the left anterior oblique (LAO) view and away from the sternum in the left lateral view. Read More

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December 2018

Recovery of metabolic impairment of patients who cleared HCV infections after direct-acting antiviral therapy.

Int J Antimicrob Agents 2018 Dec 11. Epub 2018 Dec 11.

National Institute for Infectious Diseases Lazzaro Spallanzani-IRCCS- Via Portuense, 292- 00149 Rome, Italy. Electronic address:

Chronic Hepatitis C (CHC) is a complex disease that can affect different metabolic processes, including glucose and lipids metabolic pathways, with a significant impact on development of heart disease and stroke. The recent therapy with Direct Antiviral Agents (DAAs) beyond the high efficacy on CHC eradication, showed a beneficial impact on glucose and lipid metabolism. This review aims to describe current evidences about the association between HCV infection and impairment of glucose and lipids metabolism and discuss potential public health implications at the light of new DAA therapy and their availability at global level. Read More

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December 2018

Drp1/Fis1-mediated mitochondrial fragmentation leads to lysosomal dysfunction in cardiac models of Huntington's disease.

J Mol Cell Cardiol 2018 Dec 11. Epub 2018 Dec 11.

Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA, United States. Electronic address:

Huntington's disease (HD) is a fatal hereditary neurodegenerative disorder, best known for its clinical triad of progressive motor impairment, cognitive deficits and psychiatric disturbances, is caused by CAG-repeat expansion in exon 1 of Huntingtin (HTT). However, in addition to the neurological disease, mutant HTT (mHTT), which is ubiquitously expressed in all tissues, impairs other organ systems. Not surprisingly, cardiovascular dysautonomia as well as the deterioration of circadian rhythms are among the earliest detectable pathophysiological changes in individuals with HD. Read More

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December 2018

MYBPC3 truncation mutations enhance actomyosin contractile mechanics in human hypertrophic cardiomyopathy.

J Mol Cell Cardiol 2018 Dec 11. Epub 2018 Dec 11.

Department of Molecular Physiology and Biophysics, Cardiovascular Research Institute of Vermont, University of Vermont, Burlington, VT, United States. Electronic address:

Rationale: Truncation mutations in the MYBPC3 gene, encoding for cardiac myosin-binding protein C (MyBP-C), are the leading cause of hypertrophic cardiomyopathy (HCM). Whole heart, fiber and molecular studies demonstrate that MyBP-C is a potent modulator of cardiac contractility, but how these mutations contribute to HCM is unresolved.

Objectives: To readdress whether MYBPC3 truncation mutations result in loss of MyBP-C content and/or the expression of truncated MyBP-C from the mutant allele and determine how these mutations effect myofilament sliding in human myocardium. Read More

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December 2018

Phosphodiesterase expression in the normal and failing heart.

Arch Biochem Biophys 2018 Dec 11. Epub 2018 Dec 11.

Department of Cardiovascular Disease, Mayo Medical School, Rochester, MN, 55905, USA. Electronic address:

The number of patients with heart failure with reduced ejection fraction (HFrEF) and preserved ejection fraction (HFpEF) is increasing, and for HFpEF, no therapies have clinical benefit. It has been hypothesized that PKG attenuates pathological remodelling, and increasing cGMP would be beneficial for patients with HF. However, neither the RELAX nor NEAT-HFpEF trial showed benefit. Read More

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December 2018
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Dosimetric effects of the kV based image-guided radiation therapy of prone breast external beam radiation: Towards the optimized imaging frequency.

J Appl Clin Med Phys 2018 Dec 14. Epub 2018 Dec 14.

Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.

Purpose: For prone breast treatment, daily image-guided radiation therapy (IGRT) allows couch shifting to correct breast position relative to the treatment field. This work investigates the dosimetric effect of reducing kV imaging frequencies and the feasibility of optimizing the frequency using patient anatomy or their first 3-day shifts.

Method: Thirty-seven prone breast patients who had been treated with skin marker alignment followed by daily kV were retrospectively analyzed. Read More

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December 2018
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Nutritional risk index as a predictor of mortality in acutely decompensated heart failure.

PLoS One 2018 14;13(12):e0209088. Epub 2018 Dec 14.

Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.

Background: We investigated the role of nutritional risk index (NRI) in predicting 1-year mortality in patients with acute decompensated heart failure (ADHF).

Methods: Among 5,625 cohort patients enrolled in Korean Acute Heart Failure (KorAHF) Registry, a total of 5,265 patients who were possible to calculate NRI [NRI = (1.519 x serum albumin [g/dl]) + (41. Read More

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December 2018
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Reproducibility of quantitative coronary computed tomography angiography in asymptomatic individuals and patients with acute chest pain.

PLoS One 2018 14;13(12):e0207980. Epub 2018 Dec 14.

Department of Cardiology, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.

Purpose: Quantitative computed tomography (QCT) provides important prognostic information of coronary atherosclerosis. We investigated intraobserver and interobserver QCT reproducibility in asymptomatic individuals, patients with acute chest pain without acute coronary syndrome (ACS), and patients with acute chest pain and ACS.

Methods: Fifty patients from each cohort, scanned between 01/02/2010-14/11/2013 and matched according to age and gender, were retrospectively assessed for inclusion. Read More

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December 2018

Acute heart failure in Yemen.

J Cardiovasc Med (Hagerstown) 2018 Dec 12. Epub 2018 Dec 12.

Department of Cardiology, 'Sapienza' University of Rome, Rome, Italy.

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December 2018

Clinical Evaluations of a Novel Thread Lifting Regimen Using Barbed Polyglyconate Suture for Facial Rejuvenation: Analysis Using a 3-Dimensional Imaging System.

Dermatol Surg 2018 Dec 13. Epub 2018 Dec 13.

Oaro Dermatology Clinic, Seoul, Republic of Korea.

Background: Thread lifting with absorbable sutures has recently gained prominence for rejuvenating ptotic and sagging soft tissues in aging face. A barbed, delayed absorbable polyglyconate monofilament shows significantly high tensile loads with superior flexibility and elasticity.

Objective: To evaluate the safety and efficacy of novel thread lifting regimen with barbed polyglyconate suture for counteracting the descent and laxity of the aging face. Read More

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December 2018
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Which Cut-offs for Secondary V[Combining Dot Above]O2max Criteria Are Robust to Diurnal Variations?

Med Sci Sports Exerc 2018 Dec 13. Epub 2018 Dec 13.

Department of Sport, Exercise and Health, Faculty of Medicine, University of Basel, Basel, Switzerland.

Purpose: The aim was to determine the minimum secondary exhaustion criteria cut-offs (i.e. max respiratory exchange ratio [RERmax], max heart rate [HRmax], max rating of perceived exertion [RPEmax], and max blood lactate concentration [BLmax]) necessary to determine maximum oxygen uptake (VO2max) during cardiopulmonary exercise tests (CPET), by balancing type I and type II errors. Read More

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December 2018

Randomized Controlled Trial of Symptom Management Patient Education for People With Acute Coronary Syndrome.

J Nurs Care Qual 2018 Dec 12. Epub 2018 Dec 12.

Southern Cross University and Griffith University, Gold Coast, Australia (Dr Stolic); Menzies Health Institute Queensland and Griffith University, Gold Coast, Australia (Dr Lin); and Intensive Care Unit, Princess Alexandra Hospital, Griffith University and Menzies Health Institute, Brisbane, Australia (Dr Mitchell).

Background: Poorly managed acute coronary syndrome symptoms increase the risk of subsequent cardiovascular events.

Purpose: The aim of this study was to evaluate the effectiveness of symptom management patient education on the knowledge of sublingual nitroglycerin for people with acute coronary syndrome.

Methods: A randomized controlled trial was used to evaluate the 3-resource intervention. Read More

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December 2018

Improving Patient Experience and Treatment Adherence in the Adult, Outpatient Hemodialysis Population.

J Nurs Care Qual 2018 Dec 12. Epub 2018 Dec 12.

Valley Nephrology Associates, Roanoke, Virginia (Drs Saunders and Ahmadzadeh and Ms Wright); Duke University School of Nursing, Durham, North Carolina (Drs Bush and Granger); and Duke Heart Center Nursing Research Program, Durham, North Carolina (Dr Granger).

Background: The commonly employed medication reconciliation process leaves room for mismanagement of medications in the complex end-stage renal disease patient population.

Purpose: The purpose of this quality improvement project was to implement and evaluate a multidisciplinary education and feedback intervention designed to improve self-management for adults with end-stage renal disease.

Methods: A pre-post, same subject repeated measures design was used to evaluate the intervention. Read More

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December 2018

Society of Cardiovascular Anesthesiologists/European Association of Cardiothoracic Anaesthetists Practice Advisory for the Management of Perioperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery.

Anesth Analg 2019 Jan;128(1):33-42

Department of Perioperative Medicine, Barts Heart Centre, St Bartholomew's Hospital, London, United Kingdom.

Postoperative atrial fibrillation (poAF) is the most common adverse event after cardiac surgery and is associated with increased morbidity, mortality, and hospital and intensive care unit length of stay. Despite progressive improvements in overall cardiac surgical operative mortality and postoperative morbidity, the incidence of poAF has remained unchanged at 30%-50%. A number of evidence-based recommendations regarding the perioperative management of atrial fibrillation (AF) have been released from leading cardiovascular societies in recent years; however, it is unknown how closely these guidelines are being followed by medical practitioners. Read More

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January 2019

Clinical Practice Improvement: Mind the Gap or Fall Into the Chasm.

Anesth Analg 2019 Jan;128(1):19-20

Missoula Anesthesiology and The International Heart Institute of Montana, Missoula, Montana.

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January 2019
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Reversal of ε-Aminocaproic Acid-Induced Massive Thromboemboli Using Tissue Plasminogen Activator During Cardiac Surgery: A Case Report.

A A Pract 2018 Dec 13. Epub 2018 Dec 13.

From the Department of Anesthesiology & Perioperative Care, University of California, Irvine, California.

ε-Aminocaproic acid is routinely used in cardiac surgery to prevent excess bleeding. It is rarely associated with thrombotic events. This case report illustrates the formation of intracardiac thrombi leading to massive pulmonary embolism during a coronary artery bypass graft surgery, secondary to the administration of ε-aminocaproic acid as confirmed by intraoperative transesophageal echocardiogram. Read More

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December 2018

Screening for Early Lung Cancer, Chronic Obstructive Pulmonary Disease, and Cardiovascular Disease (the Big-3) Using Low-dose Chest Computed Tomography: Current Evidence and Technical Considerations.

J Thorac Imaging 2018 Dec 13. Epub 2018 Dec 13.

Center for Medical Imaging North-East Netherlands (CMI-NEN), University Medical Center Groningen, University of Groningen.

Lung cancer, chronic obstructive pulmonary disease, and cardiovascular disease are highly prevalent in the general population and expected to cause most deaths by 2050. For these "Big-3," treatment might cure, delay, or stop the progression of disease at a very early stage. Lung nodule growth rate (a biomarker for lung cancer), emphysema/air trapping (a biomarker for chronic obstructive pulmonary disease), and coronary artery calcification (a biomarker for cardiovascular disease) are imaging biomarkers of early stages of the Big-3 that can be acquired with low-dose computed tomography (CT). Read More

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December 2018

Self-Selected Motivational Music on the Performance and Perceived Exertion of Runners.

J Strength Cond Res 2018 Dec 13. Epub 2018 Dec 13.

College of Education and Professional Studies, University of Central Oklahoma, Edmond, Oklahoma.

Clark, JC, Baghurst, T, and Redus, BS. Self-selected motivational music on the performance and perceived exertion of runners. J Strength Cond Res XX(X): 000-000, 2018-Music is used by athletes and exercisers to improve performance outcomes, but it is less known whether its properties can enhance performance at maximal intensity. Read More

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December 2018

Impact of High Fat Diet on Vasoconstrictor Reactivity of White and Brown Adipose Tissue Resistance Arteries.

Am J Physiol Heart Circ Physiol 2018 Dec 14. Epub 2018 Dec 14.

Internal Medicine-Division of Geriatrics, University of Utah, United States.

Blood flow regulation is a critical factor for tissue oxygenation and substrate supply. Increased reactivity of arteries to vasoconstrictors may increase vascular resistance, resulting in reduced blood flow. Here, we aimed to investigate the effect of high fat (HF) diet on stiffness and vasoconstrictor reactivity of white and brown adipose tissue (WAT and BAT) resistance arteries and also investigated the interconversion of both the adipose depots during HF diet condition. Read More

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December 2018

Losartan prevents the elevation of blood pressure in adipose-PRR deficient female mice while elevated circulating sPRR activates the renin angiotensin system.

Am J Physiol Heart Circ Physiol 2018 Dec 14. Epub 2018 Dec 14.

Graduate Center for Nutritional Sciences, University of Kentucky, United States.

The deletion of the prorenin receptor (PRR) in adipose tissue elevates systolic blood pressure (SBP) and circulating soluble form of PRR (sPRR) in male mice fed a high-fat diet (HF). However, sex differences in the contribution of adipose-PRR and sPRR to the regulation of the renin-angiotensin system (RAS) in key organs for blood pressure control are undefined. Therefore, we assessed blood pressure and the systemic and intrarenal RAS status in adipose-PRR KO female mice. Read More

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December 2018
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Nocturnal ventricular repolarization lability predicts cardiovascular mortality in the Sleep Heart Health Study.

Am J Physiol Heart Circ Physiol 2018 Dec 14. Epub 2018 Dec 14.

Institut für Biomedizinische Technik, TU Dresden.

Background-The objective of this study was to quantify repolarization lability and its association with sex, sleep stage and cardiovascular mortality. Methods-We analyzed polysomnographic recordings of 2,263 participants enrolled in the Sleep heart health study (SHHS-2). Beat-to-beat QT interval variability (QTV) was quantified for consecutive epochs of 5 minutes according to the dominant sleep stage (AWAKE, NREM2, NREM3, REM). Read More

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December 2018

The intuitive greater good: Testing the corrective dual process model of moral cognition.

J Exp Psychol Gen 2018 Dec 13. Epub 2018 Dec 13.

UMR CNRS 8240.

Building on the old adage that the deliberate mind corrects the emotional heart, the influential dual process model of moral cognition has posited that utilitarian responding to moral dilemmas (i.e., choosing the greater good) requires deliberate correction of an intuitive deontological response. Read More

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December 2018

Eating pathology and psychological outcomes in young adults in self-regulation interventions using daily self-weighing.

Health Psychol 2018 Dec 13. Epub 2018 Dec 13.

Warren Alpert Medical School.

Objective: Self-regulation interventions encouraging daily weighing prevent weight gain in young adults; however, concerns have been raised that such interventions may have undesirable effects on eating pathology, depression, and health-related quality of life (HRQL). The present study examined whether self-regulation interventions and self-weighing frequency were associated with these indices in normal weight individuals and those with overweight or obesity.

Methods: Young adults ( = 599), 18-35 years with a body mass index (BMI) 21. Read More

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December 2018

Age differences in everyday stressor-related negative affect: A coordinated analysis.

Psychol Aging 2018 Dec 13. Epub 2018 Dec 13.

Department of Biobehavioral Health and Medicine.

Advancing age is often characterized by preserved or even enhanced emotion regulation, which is thought to manifest in terms of age-related reductions in the within-person association between stressors and negative affect. Existing research from ecological momentary assessment and end-of-day daily diary studies examining such age-related benefits have yielded mixed results, potentially due to differences in samples, design, and measurement of everyday stressors and negative affect. We conducted a coordinated analysis of 5 ecological momentary assessments and 2 end-of-day daily diary studies to examine adult age differences in the within-person association between everyday stressors and negative affect. Read More

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December 2018

Implementing vernakalant: a novel approach to cardioversion.

Authors:
Angela Hall

Emerg Nurse 2018 Dec 11. Epub 2018 Dec 11.

Jersey General Hospital, St Helier, Jersey.

Atrial fibrillation (AF) is the most common arrhythmia, and there is a one in four lifetime risk of developing the condition for people who are over the age of 40. Vernakalant, a new addition to intravenous antiarrhythmic drugs for cardioversion of AF, is the first atrial-specific antiarrhythmic drug for pharmacological cardioversion of recent onset AF and is more effective than placebo and amiodarone. The drug offers patients an alternative to other pharmacological agents for chemical cardioversion and avoids the risks associated with electrical cardioversion. Read More

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December 2018

Review of light parameters and photobiomodulation efficacy: dive into complexity.

J Biomed Opt 2018 Dec;23(12):1-17

Massachusetts General Hospital, Wellman Center for Photomedicine, Boston, Massachusetts, United States.

Photobiomodulation (PBM) therapy, previously known as low-level laser therapy, was discovered more than 50 years ago, yet there is still no agreement on the parameters and protocols for its clinical application. Some groups have recommended the use of a power density less than 100  mW/cm2 and an energy density of 4 to 10  J/cm2 at the level of the target tissue. Others recommend as much as 50  J/cm2 at the tissue surface. Read More

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December 2018
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[Acute kidney injury as a risk marker for hospital readmission: a single-center pilot study in the general population of the Parma area].

G Ital Nefrol 2018 Dec;35(6)

Unità di Fisiopatologia dell'Insufficienza Renale Acuta e Cronica - Dipartimento di Medicina e Chirurgia, Università degli Studi di Parma.

Acute Kidney Injury (AKI) is an important issue for the healthcare system, as it is associated with high mortality and increased risk of readmission, with consequent elevated healthcare resource utilization. We investigated the incidence of AKI based on the examination of the discharge cards of all patients admitted between January 1 2011 and December 31 2015 at the Parma University Hospital, as well as the frequency and type of 30-day hospital readmission in the patients discharged with a first AKI diagnosis (index admission). The mean pooled 5-year incidence of AKI was 2. Read More

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December 2018

[The pathway of vasopressin as a pharmacological target in nephrology: a narrative review].

G Ital Nefrol 2018 Dec;35(6)

U.O.C. Nefrologia, Università cattolica del sacro cuore. Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italia.

ADH is a hormone secreted by neurohypophysis that plays different roles based on the target organ. At the renal level, this peptide is capable of causing electrolyte-free water absorption, thus playing a key role in the hydro-electrolytic balance. There are pathologies and disorders that jeopardize this balance and, in this field, ADH receptor inhibitors such as Vaptans could play a key role. Read More

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December 2018

Left Ventricular Reverse Remodeling in Recent Onset Idiopathic Dilated Cardiomyopathy Using Contemporary Echo Techniques.

Isr Med Assoc J 2018 Dec;20(12):749-753

Heart Institute, Kaplan Medical Center, Rehovot, Israel.

Background: Early identification of patients with a likelihood of cardiac improvement has important implications for management strategies.

Objectives: To evaluate whether tissue Doppler imaging (TDI) and two-dimensional (2D) strain measures may predict left ventricular (LV) improvement in patients with recent onset dilated cardiomyopathy (ROCM).

Methods: Clinical and comprehensive echo were performed at baseline and at 6 months. Read More

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December 2018

Mean Platelet Volume in Patients with Acute Ischemic Stroke with Nonvalvular Atrial Fibrillation.

Clin Lab 2018 Oct;64(11)

Background: Platelets play an important role in the pathogenesis of vascular disease, and the size of the platelets can determine their reactivity. Large platelets secrete more prothrombotic factors and aggregate more quickly. In this study, we aimed to investigate mean platelet volume (MPV) levels, which are considered to be an indication of the increase in platelet function in previous studies, in cases of acute ischemic stroke (AIS) with nonvalvular atrial fibrillation (NVAF). Read More

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October 2018
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LBH mRNA Expression and Polymorphisms in Patients with Rheumatoid Arthritis.

Clin Lab 2018 Oct;64(11)

Background: This study was performed to determine the mRNA expression levels of limb-bud and heart (LBH) in peripheral blood mononuclear cells (PBMCs) from patients with rheumatoid arthritis (RA), and to assess the associations of LBH rs7579944 and rs906868 polymorphisms with RA in a Chinese population. Methods: Real-time transcription-polymerase chain reaction analysis was used to determine the LBH mRNA expression in PBMCs from 53 patients with RA and 58 healthy controls, and LBH rs7579944 and rs906868 polymorphisms were genotyped in 328 RA patients and 449 healthy controls. Results: The LBH mRNA expression levels were significantly decreased in RA patients compared with healthy controls (p = 0. Read More

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October 2018

Exercises in anatomy: Ventricular septal defect.

Multimed Man Cardiothorac Surg 2018 Dec 6;2018. Epub 2018 Dec 6.

Institute of Genetic Medicine, Newcastle University, United Kingdom.

The phenotypic features of the heart with ventricular septal defects will be shown in this video tutorial. There is still no agreement as to whether it's best to categorize lesions on the basis of their geography or their borders. Both geography and borders are features that are of importance. Read More

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December 2018

Repair of tricuspid papillary muscle rupture after percutaneous coronary intervention.

Authors:
Shinji Kanemitsu

Multimed Man Cardiothorac Surg 2018 Dec 6;2018. Epub 2018 Dec 6.

Department of Thoracic and Cardiovascular Surgery Mie University Graduate School of Medicine 2-174 Edobashi, Tsu, Mie 514-8507, Japan.

Papillary muscle rupture is a rare complication after myocardial infarction and almost all cases occur in the mitral valve papillary muscle. Tricuspid regurgitation development after right ventricular myocardial infarction caused by papillary muscle rupture is extremely rare.  In this video tutorial we present a 70-year-old man with massive tricuspid regurgitation caused by papillary muscle rupture after percutaneous stenting of the right coronary artery. Read More

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December 2018

One-stage transmediastinal surgical approach for extensive aortic pathology.

Multimed Man Cardiothorac Surg 2018 Dec 4;2018. Epub 2018 Dec 4.

SS. Antonio e Biagio e Cesare Arrigo Hospital of Alessandria Piedmont Italy.

"One-stage" transmediastinal replacement of the thoracic aorta provides an alternative treatment to single or multiple stage hybrid procedures for patients with ascending, arch, and descending thoracic aorta aneurysm. The patient is placed on bypass and cooled. During circulatory arrest, after surgical treatment of the aortic valve and root where appropriate, the entire ascending aorta is excised and the transverse arch is opened longitudinally. Read More

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December 2018
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