191,000 results match your criteria Coronary Artery Atherosclerosis


Atrioventricular node ablation and pacing for atrial tachyarrhythmias: A meta-analysis of postoperative outcomes.

Int J Cardiol 2022 Jun 25. Epub 2022 Jun 25.

Department of Cardiac Surgery, Spedali Civili di Brescia, University of Brescia, Brescia, Italy.

Background: Atrioventricular node ablation (AVNA) and pacemaker (PM) is performed in symptomatic atrial fibrillation (AF) unresponsive to medical treatment and percutaneous ablation. This meta-analysis evaluated results after AVNA and PM.

Methods: Primary and secondary endpoints were early/late overall/cardiac-related mortality and early/late postoperative complications. Read More

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Association of Plasma Ninjurin-1 and SYNTAX Score in Patients with Coronary Artery Disease.

Clin Biochem 2022 Jun 25. Epub 2022 Jun 25.

Heart Center & Beijing Key Laboratory of Hypertension, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China. Electronic address:

Background: Expression of nerve injury-induced protein 1 (Ninj1) is associated with several inflammatory disease. The soluble Ninj1 is an antiatherogenic protein. However, the role of plasma Ninj1 levels in patients with CAD and its correlation with the severity of the disease remains unknown. Read More

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Clinical outcomes of patients with coronary microvascular dysfunction in absence of obstructive coronary atherosclerosis.

J Cardiovasc Med (Hagerstown) 2022 Jul 23;23(7):421-426. Epub 2022 Jun 23.

Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Dipartimento di Medicina Cardiovascolare, Rome.

Up to 50% of patients presenting with stable, mainly exercise-induced, chest pain and 10-20% of those admitted to hospital with chest pain suggesting an acute coronary syndrome show normal or near-normal coronary arteries at angiography. Coronary microvascular dysfunction (CMD) is a major cause of symptoms in these patients. However, controversial data exist about their prognosis. Read More

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Clinical outcomes of patients with coronary microvascular dysfunction in absence of obstructive coronary atherosclerosis.

J Cardiovasc Med (Hagerstown) 2022 Jun 23. Epub 2022 Jun 23.

Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Dipartimento di Medicina Cardiovascolare, Rome.

Up to 50% of patients presenting with stable, mainly exercise-induced, chest pain and 10-20% of those admitted to hospital with chest pain suggesting an acute coronary syndrome show normal or near-normal coronary arteries at angiography. Coronary microvascular dysfunction (CMD) is a major cause of symptoms in these patients. However, controversial data exist about their prognosis. Read More

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Caffeine intake in adults with cardiovascular diseases; A cross-sectional study.

Nutr Health 2022 Jun 28:2601060221105030. Epub 2022 Jun 28.

Department of Cardiology, Tekirdağ Namık Kemal University, Medicine School, Tekirdag, Turkey.

Caffeine in the safe dose range has been associated with a reduction in the risk of chronic diseases. There is evidence that caffeine intake has both protective and negative effects on cardiovascular diseases. This study aimed to investigate caffeine intake in cardiovascular patients. Read More

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[Association of liver damage with coronary artery lesion and no response to intravenous immunoglobulin in the acute stage of Kawasaki disease].

Zhongguo Dang Dai Er Ke Za Zhi 2022 Jun;24(6):681-686

Department of Cardiology, Beijing Children's Hospital, Capital Medical University/National Center for Children's Health, Beijing 100045, China.

Objectives: To summarize the clinical features of liver damage in children in the acute stage of Kawasaki disease (KD), and to investigate the clinical value of liver damage in predicting coronary artery lesion and no response to intravenous immunoglobulin (IVIG) in children with KD.

Methods: The medical data were collected from 925 children who were diagnosed with KD for the first time in Beijing Children's Hospital from January 1, 2016 to December 31, 2017. According to the presence or absence of abnormal alanine aminotransferase (ALT) level on admission, the children were divided into a liver damage group (=284) and a non-liver damage group (=641). Read More

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Catheter-induced coronary artery and aortic dissections. A study of the mechanisms, risk factors, and propagation causes.

Cardiol J 2022 Jun 28. Epub 2022 Jun 28.

Department of Cardiology and Interventional Angiology, Kashubian Center for Heart and Vascular Diseases in Wejherowo, Pomeranian Hospitals, Wejherowo, Poland.

Background: Only the incidence, management, and prognosis of catheter-induced coronary artery and aortic dissections have been systematically studied until now. We sought to evaluate their mechanisms, risk factors, and propagation causes.

Methods: Electronic databases containing 76,104 procedures and complication registries from 2000-2020 were searched and relevant cineangiographic studies adjudicated. Read More

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Nighttime hemodynamic phenotype. A novel risk factor for cardiovascular disease, especially heart failure: the practitioner-based nationwide JAMP study.

Clin Res Cardiol 2022 Jun 27. Epub 2022 Jun 27.

Genki Plaza Medical Center for Health Care, Tokyo, Japan.

Background: Non-dipper and riser patterns of nocturnal blood pressure (BP) are risk factors for cardiovascular disease (CVD), including heart failure (HF). However, the risk associated with a disrupted nocturnal pattern of heart rate is not well known.

Objectives: To investigate whether the nighttime heart rate is a risk factor for HF, alongside nighttime BP phenotype. Read More

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Sex differences in the clinical presentation of acute coronary syndromes.

Curr Probl Cardiol 2022 Jun 24:101300. Epub 2022 Jun 24.

Department of Cardiology. Hospital de Alta Complejidad El Cruce. Florencio Varela. Buenos Aires. Argentina; GEDIC. Grupo de Estudio, Docencia e Investigación Clínica. Buenos Aires. Argentina.

The clinical presentation of acute coronary syndromes (ACS) as ST-elevation ACS (STEACS) or non-ST-elevation ACS (NSTEACS) differs between women and men. The aim of this study was to describe the difference in the clinical presentation of ACS between sexes. A total of 10,019 patients included in the Epi-Cardio Registry were analyzed. Read More

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Omega-3 fatty acids, subclinical atherosclerosis, and cardiovascular events: Implications for primary prevention.

Atherosclerosis 2022 Jun 20;353:11-19. Epub 2022 Jun 20.

Ciccarone Center for the Prevention of Cardiovascular Disease, Division of Cardiology, Johns Hopkins University School of Medicine, USA. Electronic address:

Background And Aims: High-dose eicosapentaenoic acid (EPA) therapy was beneficial in high-risk patients without clinical cardiovascular disease (CVD). Whether higher plasma levels of EPA and docosahexaenoic acid (DHA) have similar benefits in those without subclinical CVD is unclear. We aim to evaluate the interplay between plasma omega-3 fatty acids and coronary artery calcium (CAC) in relation to CVD events. Read More

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Release of MMP-2 in the circulation of patients with acute coronary syndromes undergoing percutaneous coronary intervention: Role of platelets.

Thromb Res 2022 Jun 22;216:84-89. Epub 2022 Jun 22.

Department of Medicine and Surgery, Division of Internal and Cardiovascular Medicine, University of Perugia, Perugia, Italy. Electronic address:

Introduction: Matrix metalloproteinases (MMPs) of atherosclerotic tissue contribute to plaque rupture triggering acute coronary syndromes (ACS). Several MMPs, including MMP-2, are also contained in platelets and released upon activation. An increase in circulating levels of MMP-2 has been reported in patients undergoing percutaneous coronary interventions (PCI), but its time-course and origin remain unclear. Read More

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Impact of phase angle and sarcopenia estimated by bioimpedance analysis on clinical prognosis in patients undergoing hemodialysis: A retrospective study.

Medicine (Baltimore) 2022 Jun 24;101(25):e29375. Epub 2022 Jun 24.

Department of Internal Medicine, Gyeongsang National University Changwon Hospital, Changwon, South Korea.

Abstract: Bioimpedance analysis (BIA) has been widely used in the evaluation of body composition in patients undergoing maintenance hemodialysis. We conducted this study to evaluate impact of phase angle (PA) and sarcopenia measured by BIA on clinical prognosis in these patients.This longitudinal retrospective study enrolled patients who underwent hemodialysis between January 2016 and March 2019. Read More

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Coronary sinus reducer for the treatment of chronic refractory angina pectoris.

Future Cardiol 2022 Jun 27. Epub 2022 Jun 27.

Interventional Cardiology Unit, GVM Care & Research Maria Cecilia Hospital, Via Madonna di Genova 1, Cotignola, RA, 48033, Italy.

Refractory angina represents the final stage of chronic coronary artery disease, where anginal symptoms persist despite complete epicardial coronary artery revascularization and maximally tolerated pharmacological therapy. Percutaneous narrowing of the coronary sinus with the Coronary Sinus Reducer device was first attempted in humans in 2005 and has been shown to improve angina symptoms and the quality of life of patients suffering chronic refractory angina. It was recently included in the European guidelines for the management of chronic coronary syndrome and is progressively gaining popularity. Read More

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Contemporary prevalence of coronary artery disease in patients referred for heart valve surgery.

J Cardiovasc Surg (Torino) 2022 Jun 22. Epub 2022 Jun 22.

Cardiology Department, Centro Hospitalar de Lisboa Central, Hospital de Santa Marta, Lisbon, Portugal.

Background: Patients undergoing heart valve surgery are routinely evaluated for the presence of coronary artery disease (CAD). Currently, concomitant valve intervention and surgical revascularization is recommended when there is obstructive CAD. Our objective was to evaluate the prevalence of CAD, its treatment strategies and their prognostic implications in a contemporary population of patients with valvular heart disease (VHD) referred for valve surgery (HVS). Read More

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Isolated septal myocardial infarction due to coronary spasm.

Authors:
Chan-Hee Lee

Coron Artery Dis 2022 Jun 27. Epub 2022 Jun 27.

Division of Cardiology, Department of Internal Medicine, Yeungnam University Medical Center, Daegu, Republic of Korea.

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Surgery for Anomalous Aortic Origin of a Coronary Artery (AAOCA) in Children and Adolescents: A Meta-Analysis.

World J Pediatr Congenit Heart Surg 2022 Jul;13(4):485-494

Pediatric and Congenital Cardiac Surgery Unit, Padova, Veneto, Italy.

We conducted a systematic review and meta-analysis of the literature to assess the outcomes of surgery for the anomalous aortic origin of a coronary artery in children and young adults (<30 years). Thirteen publications were selected, including a total of 384 patients. Unroofing of the intramural segment was adopted in 92% (95% CI: 81%-98%) of cases, with pooled early and late mortality of 0% (95% CI: 0%-0. Read More

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Assessment of left main coronary artery disease: a comparison between invasive and noninvasive.

Coron Artery Dis 2022 Jun 27. Epub 2022 Jun 27.

The Lundquist Institute, Harbor-UCLA Medical Center, Torrance, California.

Left main coronary artery disease has significant therapeutic as well as prognostic implications. The presence of left main coronary artery stenosis is strongly associated with poor short- and long-term prognoses. Accurate identification of left main stenosis is extremely important since it would be the main factor to guide management. Read More

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Antithrombotic Therapy after Transcatheter Aortic Valve Replacement.

Heart Views 2022 Jan-Mar;23(1):10-15. Epub 2022 May 16.

Department of Adult Cardiology, Heart Hospital, Hamad Medical Corporation, Doha, Qatar.

Transcatheter aortic valve replacement (TAVR) is a treatment option for patients with asymptomatic severe aortic stenosis who are candidates for a bioprosthesis across the entire spectrum of risk. TAVR carries a risk for thrombotic and bleeding events, focusing on the importance of defining the optimal antithrombotic regimen. Patients undergoing TAVR are mostly elderly and have many comorbidities such as atrial fibrillation (AF) requiring oral anticoagulants (OACs) or coronary artery disease requiring antiplatelet agents. Read More

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Long-Term Outcomes for Chinese COPD Patients After PCI: A Propensity Score Matched, Double-Cohort Study.

Front Cardiovasc Med 2022 9;9:827635. Epub 2022 Jun 9.

Department of Cardiology and Institute of Vascular Medicine, Peking University Third Hospital, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing Key Laboratory of Cardiovascular Receptors Research, Beijing, China.

Objectives: The aim of this study was to analyze long-term outcomes of Chinese coronary artery disease (CAD) patients with (and without) chronic obstructive pulmonary disease (COPD) after percutaneous coronary intervention (PCI).

Background: Chronic obstructive pulmonary disease is a chronic condition which often develops in conjunction with CAD. PCI is a core therapy for CAD, although we still need to understand CAD-COPD outcomes and to identify factors that influence prognoses, across ethnicities. Read More

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Implications of the heterogeneity between guideline recommendations for the use of low dose aspirin in primary prevention of cardiovascular disease.

Am J Prev Cardiol 2022 Sep 6;11:100363. Epub 2022 Jun 6.

Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Johns Hopkins University Medical Center, Baltimore, MD, United States.

The most recent primary cardiovascular disease (CVD) prevention clinical guidelines used in Europe, Italy, the USA, China, and South Korea differ in aspects of their approach to CVD risk assessment and reduction. Low dose aspirin use is recommended in certain high-risk patients by most but not all the countries. Assessment of traditional risk factors and which prediction models are commonly used differ between countries. Read More

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September 2022

Addressing unmeasured confounding bias with a prior knowledge guided approach: coronary artery bypass grafting (CABG) versus percutaneous coronary intervention (PCI) in patients with stable ischemic heart disease.

Health Serv Outcomes Res Methodol 2022 Jun 21:1-21. Epub 2022 Jun 21.

Kaiser Permanente Center for Effectiveness and Safety Research and the Bernard J. Tyson School of Medicine, Pasadena, CA USA.

Unmeasured confounding undermines the validity of observational studies. Although randomized clinical trials (RCTs) are considered the "gold standard" of study types, we often observe divergent findings between RCTs and empirical settings. We present the "L-table", a simulation-based, prior knowledge (e. Read More

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Practical Workflow for Cardiovascular Assessment and Follow-Up in Kawasaki Disease Based on Expert Opinion.

Front Pediatr 2022 9;10:873421. Epub 2022 Jun 9.

Department of Pediatric Cardiology, Emma Children's Hospital, Amsterdam University Medical Center (UMC), University of Amsterdam, Amsterdam, Netherlands.

Background: Approximately 25% of the patients with a history of Kawasaki disease (KD) develop coronary artery pathology if left untreated, with coronary artery aneurysms (CAA) as an early hallmark. Depending on the severity of CAAs, these patients are at risk of myocardial ischemia, infarction and sudden death. In order to reduce cardiac complications it is crucial to accurately identify patients with coronary artery pathology by an integrated cardiovascular program, tailored to the severity of the existing coronary artery pathology. Read More

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Non-pulmonary complications after lung transplantation: Part I.

Indian J Thorac Cardiovasc Surg 2022 Jul 8;38(Suppl 2):280-289. Epub 2021 Oct 8.

Lung Transplant Program, University of Texas Southwestern Medical Center, 5939 Harry Hines Blvd. Suite 603, Dallas, TX 75235-8550 USA.

Lung transplantation (LT) is a viable therapeutic option in the treatment of advanced lung disease. With improvements in post-transplant survival, complications involving different organ systems after LT are increasingly seen. While non-infectious, extrapulmonary complications after LT are not frequently responsible for early post-transplant mortality, they significantly impact the quality of life and long-term survival. Read More

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Indications, Complications, and Outcomes of Cardiac Surgery After Heart Transplantation: Results From the Cash Study.

Front Cardiovasc Med 2022 9;10:879612. Epub 2022 Jun 9.

Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria.

Background: Allograft pathologies, such as valvular, coronary artery, or aortic disease, may occur early and late after cardiac transplantation. Cardiac surgery after heart transplantation (CASH) may be an option to improve quality of life and allograft function and prolong survival. Experience with CASH, however, has been limited to single-center reports. Read More

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Right ventricular laceration caused by sternal wire fracture following cardiac surgery: a case report.

Indian J Thorac Cardiovasc Surg 2022 Jul 14;38(4):418-421. Epub 2022 Feb 14.

Division of Cardiac Surgery, Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia Canada.

Sternal dehiscence and sternal wire fractures are of significant concern for patients post cardiac surgery. Right ventricular laceration resulting from injury secondary to fractured sternal wires is a rare cause of life-threatening postoperative hemorrhage. A 68-year-old male presented for coronary artery bypass grafting (CABG). Read More

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Perioperative outcomes of general versus spinal anesthesia in the lumbar spine surgery population: A systematic review and meta-analysis of data from 2005 through 2021.

J Clin Orthop Trauma 2022 Jul 16;30:101923. Epub 2022 Jun 16.

Duke University Department of Neurosurgery, Durham, NC, USA.

Study Design: Meta-analysis.

Objectives: Perform a systematic review and meta-analysis to determine the perioperative utility of general versus spinal anesthesia in the lumbar spine surgery population.

Methods: PubMed and Embase were queried for manuscripts reporting perioperative outcomes for patients undergoing one to three-level lumbar spine surgery (including decompression, fusion, and decompression with fusion) using either general or spinal anesthesia. Read More

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Non-optimum temperature increases risk and burden of acute myocardial infarction onset: A nationwide case-crossover study at hourly level in 324 Chinese cities.

EClinicalMedicine 2022 Aug 17;50:101501. Epub 2022 Jun 17.

School of Public Health, Key Lab of Public Health Safety of the Ministry of Education and NHC Key Lab of Health Technology Assessment, Fudan University, Shanghai, China.

Background: The associations of ambient temperature with acute myocardial infarction (AMI) have seldom been examined based on the time of symptom onset.

Methods: We conducted a time-stratified case-crossover study among 1,046,773 eligible AMI patients from 2,093 hospitals in 324 Chinese cities from January 1, 2015 to June 30, 2021, after excluding those transferred from other hospitals or having not reported the time of symptom onset. Hourly exposure to ambient temperature was calculated as multiple moving 24-h averages (days) before hourly onset of AMI symptoms. Read More

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Cardiac-Related Lesions in Newly Diagnosed Patients With Acute Leukemia: A Chinese Population-Based Real-World Study.

Front Med (Lausanne) 2022 9;9:844350. Epub 2022 Jun 9.

Department of Hematology, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.

The relationship between newly diagnosed acute leukemia (AL) and heart-related lesions remains unclear. This study aimed to investigate baseline cardiac function and risk of cardiovascular diseases (CVDs) in patients with new-onset AL, and provide data on cardiac management strategies for patients with AL. We retrospectively collected data on baseline characteristics, echocardiography, and biochemical blood indicators (e. Read More

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Atypical variant takotsubo cardiomyopathy secondary to pheochromocytoma.

Proc (Bayl Univ Med Cent) 2022 22;35(4):526-528. Epub 2022 Mar 22.

Department of Radiology, Baylor University Medical Center, Dallas, Texas.

A 39-year-old woman presented with chest pain and elevated troponin levels. Cardiac catheterization demonstrated no coronary artery disease, with findings consistent with atypical variant takotsubo cardiomyopathy. Further workup showed elevated plasma fractionated metanephrines suggestive of pheochromocytoma. Read More

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Preoperative Vascular Function Assessment and Perioperative Vascular Events in Patients Posted for Elective Non-cardiac Surgeries.

Cureus 2022 Jun 22;14(6):e26188. Epub 2022 Jun 22.

Anesthesiology and Critical Care, Jawaharlal Institute of Postgraduate Medical Education & Research, Puducherry, IND.

Background Coronary atherosclerosis is usually asymptomatic until a major cardiac event occurs. Surgery is one of the major stress factors that play a role in hastening vascular deterioration in susceptible patients. Non-invasive tests to detect atherosclerosis and endothelial dysfunction have started gaining popularity nowadays, and of the several options, carotid artery intima-media thickness (IMT) and radial artery flow-mediated dilation (FMD) are two promising tests for detecting cardiovascular impairment. Read More

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