736 results match your criteria Corneal Topography and Imaging


Modified wavelength scanning interferometry for simultaneous tomography and topography of the cornea with Fourier domain optical coherence tomography.

Biomed Opt Express 2018 Sep 27;9(9):4443-4458. Epub 2018 Aug 27.

Department of Biomedical Engineering, University of Houston, Houston, TX 77004, USA.

Visual acuity is dependent on corneal shape and size. A minor variation in surface geometry can cause a deformation of corneal geometry, which affects its optical performance. In this work we demonstrate an algorithm for the simultaneous measurement of corneal tomography and topography with a traditional point-scanning Fourier domain optical coherence tomography (FD-OCT) system. Read More

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http://dx.doi.org/10.1364/BOE.9.004443DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157774PMC
September 2018

Tomographic and Biomechanical Scheimpflug Imaging for Keratoconus Characterization: A Validation of Current Indices.

J Refract Surg 2018 Dec;34(12):840-847

Purpose: To analyze the potential benefit of the newly developed Tomography and Biomechanical Index (TBI) for early keratoconus screening.

Methods: In this retrospective study, the discriminatory power of the corneal tomography Belin/Ambrósio Enhanced Ectasia Display (BAD-D) index and the newly developed Corvis Biomechanical Index (CBI) and TBI to differentiate between normal eyes, manifest keratoconus eyes (KCE), very asymmetric keratoconus eyes with ectasia (VAE-E), and their fellow eyes with either regular topography (VAE-NT) or regular topography and tomography (VAE-NTT) were analyzed by applying the t test (for normal distribution), Wilcoxon matched-pairs test (if not normally distributed), and receiver operating characteristic curve (ROC). The DeLong test was used to compare the area under the ROC (AUROC). Read More

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http://dx.doi.org/10.3928/1081597X-20181012-01DOI Listing
December 2018
1 Read
3.468 Impact Factor

Pellucid marginal degeneration: Detection, discrimination from other corneal ectatic disorders and progression.

Cont Lens Anterior Eye 2018 Nov 22. Epub 2018 Nov 22.

Group of Optics and Visual Perception. Department of Optics, Pharmacology and Anatomy, University of Alicante, Spain. Electronic address:

Pellucid marginal degeneration (PMD) is a non-inflammatory ectatic corneal disease characterized by a narrow band of corneal thinning separated from the limbus by a relatively uninvolved area 1-2 mm in width. It is a rare corneal disorder that shares many clinical characteristics with other corneal ectasias, such as keratoconus, keratoglobus or Terrien marginal degeneration. PMD usually starts later in life than keratoconus and progresses slower than keratoconus. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13670484183094
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http://dx.doi.org/10.1016/j.clae.2018.11.010DOI Listing
November 2018
6 Reads

Age-related variations in corneal geometry and their association with astigmatism: The Yamagata Study (Funagata).

Medicine (Baltimore) 2018 Oct;97(43):e12894

Department of Ophthalmology and Visual Sciences.

To investigate how aging affects corneal geometry in Japanese adults, and the association between corneal geometry and astigmatism.We included 421 participants who had undergone systemic and ophthalmological examinations in 2015 in Funagata town, Yamagata, Japan. Corneal topographic data were obtained using anterior-segment optical coherence tomography (CASIA SS-1000). Read More

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http://dx.doi.org/10.1097/MD.0000000000012894DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221551PMC
October 2018
6 Reads

Keratoconus severity identification using unsupervised machine learning.

PLoS One 2018 6;13(11):e0205998. Epub 2018 Nov 6.

Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America.

We developed an unsupervised machine learning algorithm and applied it to big corneal parameters to identify and monitor keratoconus stages. A big dataset of corneal swept source optical coherence tomography (OCT) images of 12,242 eyes acquired from SS-1000 CASIA OCT Imaging Systems in multiple centers across Japan was assembled. A total of 3,156 eyes with valid Ectasia Status Index (ESI) between zero and 100% were selected for the downstream analysis. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0205998PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219768PMC
November 2018
7 Reads

Outcome of deep anterior lamellar keratoplasty patients with intraoperative Descemet's membrane perforation: A retrospective cross-sectional study.

Indian J Ophthalmol 2018 Nov;66(11):1574-1579

Department of Cornea, Cataract and Refractive Services, The Eye Foundation Hospital, Coimbatore, Tamil Nadu, India.

Purpose: To evaluate functional and anatomical outcome in patients undergoing deep anterior lamellar keratoplasty (DALK) with intraoperative Descemet's membrane (DM) perforation (macro and micro).

Methods: A retrospective cross sectional study (January 2009 to December 2015) of sixteen eyes of sixteen patients which included nine patients of advanced keratoconus (KC), two patients with paracentral DM scarring post hydrops, KC with Bowman's membrane scarring, macular corneal dystrophy and one patient of advanced Pellucid Marginal Degeneration (PMD). All underwent DALK with intraoperative DM perforation. Read More

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http://dx.doi.org/10.4103/ijo.IJO_282_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213700PMC
November 2018
9 Reads

Comparative analysis of visual outcomes and ocular aberrations following wavefront optimized and topography-guided customized femtosecond laser keratomileusis for myopia and myopic astigmatism: A contralateral eye study.

Indian J Ophthalmol 2018 Nov;66(11):1558-1561

Department of Cornea and Refractive Services, The Eye Foundation, 582A, DB Road, RS Puram, Coimbatore, Tamil Nadu, India.

Purpose: To compare the visual outcomes and higher order aberrations (HOAs) following wavefront optimized (WFO) laser in situ keratomileusis (LASIK) versus topography-guided customized ablation (TCAT) LASIK for myopia and myopic astigmatism.

Methods: Patients who underwent femtosecond-assisted LASIK for myopic correction between August 2016 and October 2017 were included in this interventional prospective case series. The following parameters were evaluated preoperatively and at 3 months' postoperative visit: uncorrected distance vision acuity (UDVA) and corrected distance vision acuity (CDVA), manifest refraction, and HOAs. Read More

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http://www.ijo.in/text.asp?2018/66/11/1558/244063
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http://dx.doi.org/10.4103/ijo.IJO_507_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213678PMC
November 2018
8 Reads

The Role of Ocular Response Analyzer in Differentiation of Forme Fruste Keratoconus From Corneal Astigmatism.

Eye Contact Lens 2018 Aug 10. Epub 2018 Aug 10.

Department of Ophthalmology (A.K., K.A., C.G.), Bagcilar Training and Research Hospital, University of Health Sciences, Istanbul, Turkey; and Department of Ophthalmology (S.K.E.), Istanbul Medipol University, Istanbul, Turkey.

Purpose: To determine the diagnostic accuracy of corneal biomechanical factors in differentiating patients with forme fruste keratoconus (FFKC) from astigmatic and normal cases.

Methods: A total of 50 eyes with FFKC, 50 with astigmatism and 50 normal eyes, were included in this study. All patients had a detailed ophthalmologic examination including slit-lamp evaluation, Goldmann tonometry, indirect fundoscopy, topography by Scheimpflug imaging biomicroscopic anterior and posterior segment examination, and corneal biomechanical and intraocular pressure evaluation with ocular response analyzer (ORA). Read More

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http://Insights.ovid.com/crossref?an=00140068-900000000-9921
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http://dx.doi.org/10.1097/ICL.0000000000000541DOI Listing
August 2018
1 Read

An In Vitro Model for Assessing Corneal Keratocyte Spreading and Migration on Aligned Fibrillar Collagen.

J Funct Biomater 2018 Sep 21;9(4). Epub 2018 Sep 21.

Department of Ophthalmology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Background: Corneal stromal cells (keratocytes) are responsible for developing and maintaining normal corneal structure and transparency, and for repairing the tissue after injury. Corneal keratocytes reside between highly aligned collagen lamellae in vivo. In addition to growth factors and other soluble biochemical factors, feedback from the extracellular matrix (ECM) itself has been shown to modulate corneal keratocyte behavior. Read More

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http://www.mdpi.com/2079-4983/9/4/54
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http://dx.doi.org/10.3390/jfb9040054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306816PMC
September 2018
7 Reads

Evaluation of Scheimpflug imaging parameters in blepharospasm and normal eyes.

BMC Ophthalmol 2018 Sep 5;18(1):239. Epub 2018 Sep 5.

Department of Ophthalmology, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.

Background: To investigate changes in corneal elevation, pachymetry, and keratometry in discriminating between normal and blepharospasm eyes, as measured by the Pentacam rotating Scheimpflug camera.

Methods: This was a prospective, cross-sectional study. A total of 47 consecutive patients with a range of blepharospasm severity and 40 age- and sex- matched healthy subjects were included, one eye of each subject was randomly chosen for data analysis. Read More

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http://dx.doi.org/10.1186/s12886-018-0897-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126042PMC
September 2018
1 Read

The Sheep Cornea: Structural and Clinical Characteristics.

Curr Eye Res 2018 Dec 23;43(12):1432-1438. Epub 2018 Aug 23.

a The University of Auckland, Department of Ophthalmology , New Zealand National Eye Centre , Auckland , New Zealand.

Purpose: The aim of this study was to perform qualitative and quantitative analyses to characterize the corneas of young, healthy sheep.

Materials And Methods: Eight healthy male sheep, 10 months to 1 year of age, were included as experimental subjects. Central corneal thickness was measured using a handheld pachymeter, and an Easygraph corneal topographer provided topographic maps. Read More

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http://dx.doi.org/10.1080/02713683.2018.1510970DOI Listing
December 2018
12 Reads

Corneal densitometry in high myopia.

BMC Ophthalmol 2018 Jul 25;18(1):182. Epub 2018 Jul 25.

Department of Ophthalmology, Shanxi Eye Hospital, No. 100 Fudong Street, Taiyuan, 030002, Shanxi, People's Republic of China.

Background: To investigate corneal densitometry values obtained using Scheimpflug tomography in normal and highly myopic (HM) eyes and to assess the differences in densitometry values between them.

Methods: Highly myopic and normal corneas were examined using the Pentacam Scheimpflug imaging system. Corneal densitometry was automatically performed over a 12-mm diameter area, which was divided on the basis of annular concentric zones (0-2 mm, 2-6 mm, 6-10 mm, 10-12 mm, total diameter) and depth (anterior layer: inner 120 μm; center layer: from 120 μm to the last 60 μm; posterior layer: last 60 μm; total corneal thickness). Read More

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http://dx.doi.org/10.1186/s12886-018-0851-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060530PMC
July 2018
1 Read

Corneal hysteresis in post-radial keratotomy primary open-angle glaucoma.

Graefes Arch Clin Exp Ophthalmol 2018 Oct 23;256(10):1971-1976. Epub 2018 Jul 23.

Little Rock Eye Clinic, 201 Executive Court, Little Rock, AR, 72205, USA.

Purpose: Corneal hysteresis (CH) is a corneal biomechanical property measured by the ocular response analyzer (ORA). It is associated with primary open-angle glaucoma development, progression, and severity as well as intraocular pressure (IOP) measurement. Decreases in CH and changes in IOP measurements have been described for laser-assisted refractive surgery; however, patients with prior radial keratotomy (RK) have not been examined. Read More

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http://dx.doi.org/10.1007/s00417-018-4073-yDOI Listing
October 2018

Pentacam Accuracy in Discriminating Keratoconus From Normal Corneas: A Diagnostic Evaluation Study.

Eye Contact Lens 2019 Jan;45(1):46-50

Noor Research Center for Ophthalmic Epidemiology (H.H., S.B.), Noor Eye Hospital, Tehran, Iran; Department of Medical Surgical Nursing (M.K.), School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Noor Ophthalmology Research Center (R.P.), Noor Eye Hospital, Tehran, Iran; Refractive Errors Research Center (H.O., R.Y.), Mashhad University of Medical Sciences, Mashhad, Iran; Department of Optometry (A.A., A.Y.), School of Paramedical Sciences, Mashhad University of Medical Sciences, Mashhad, Iran; and Eye Research Center (M.A.), Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.

Objectives: This study aims to determine the diagnostic ability of Pentacam indices for keratoconus and identifying the best index for differentiating diseased from normal cases.

Method: In this study, 150 keratoconus patients and 150 refractive surgery candidates with a definitive diagnosis of normal healthy corneas were enrolled. Initially, the placido disk topography imaging was performed. Read More

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http://dx.doi.org/10.1097/ICL.0000000000000531DOI Listing
January 2019
1 Read
1.679 Impact Factor

Variation of Lenticule Thickness for SMILE in Low Myopia.

J Refract Surg 2018 Jul;34(7):453-459

Purpose: To report the impact of increasing minimum lenticule thickness on the safety and efficacy of small incision lenticule extraction (SMILE) in low myopia up to -3.50 diopters (D).

Methods: SMILE was performed in 76 eyes of 76 patients. Read More

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https://www.healio.com/doiresolver?doi=10.3928/1081597X-2018
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http://dx.doi.org/10.3928/1081597X-20180516-01DOI Listing
July 2018
3 Reads

Simultaneous Estimation of Corneal Topography, Pachymetry, and Curvature.

IEEE Trans Med Imaging 2018 Nov 15;37(11):2463-2473. Epub 2018 May 15.

Identification of objective criteria to correctly diagnose ectatic diseases of the cornea or to detect early stages of corneal ectasia is of great interest in ophthalmology and optometry. Metrics for diagnosis typically employed are curvature maps (axial/sagittal, tangential); elevation map of the anterior surface of the cornea with respect to a reference sphere; and pachymetry (thickness) map of the cornea. We present evidence that currently used curvature maps do not represent the actual curvatures (principal or mean) in a human cornea. Read More

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http://dx.doi.org/10.1109/TMI.2018.2836304DOI Listing
November 2018

Glare-free retinal imaging using a portable light field fundus camera.

Biomed Opt Express 2018 Jul 20;9(7):3178-3192. Epub 2018 Jun 20.

Queensland University of Technology, Brisbane, QLD 4000, Australia.

We present the retinal plenoptoscope, a novel light field retinal imaging device designed to overcome many of the problems that limit the use of portable non-mydriatic fundus cameras, including image quality and lack of stereopsis. The design and prototype construction of this device is detailed and the ideal relationship between the eye pupil, system aperture stop and micro-image separation is investigated. A comparison of the theoretical entrance pupil size, multi-view baseline and depth resolution indicates that a higher degree of stereopsis is possible than with stereo fundus cameras. Read More

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http://dx.doi.org/10.1364/BOE.9.003178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033554PMC
July 2018
2 Reads

Additive effects of orthokeratology and atropine 0.01% ophthalmic solution in slowing axial elongation in children with myopia: first year results.

Jpn J Ophthalmol 2018 Sep 4;62(5):544-553. Epub 2018 Jul 4.

Department of Ophthalmology, Saitama Medical Center, Jichi Medical University, 1-847 Amanuma-cho, Omiya-ku, Saitama-shi, Saitama, 330-8503, Japan.

Purpose: To investigate the additive effects of orthokeratology (OK) and atropine 0.01% ophthalmic solution, both of which are effective procedures to slow axial elongation in children with myopia.

Study Design: Prospective randomized clinical trial. Read More

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http://link.springer.com/10.1007/s10384-018-0608-3
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http://dx.doi.org/10.1007/s10384-018-0608-3DOI Listing
September 2018
9 Reads

Intrasubject Repeatability and Interdevice Agreement of Anterior Chamber Depth Measurements by Orbscan and Pentacam in Different Grades of Keratoconus.

Eye Contact Lens 2019 Jan;45(1):51-54

Noor Research Center for Ophthalmic Epidemiology (H.H., A.T.), Noor Eye Hospital, Tehran, Iran; Noor Ophthalmology Research Center (A.A.), Noor Eye Hospital, Tehran, Iran; Department of Optometry (M.A.A., S.R.), Faculty of Rehabilitation Science, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Refractive Errors Research Center (A.Y.), Mashhad University of Medical Sciences, Mashhad, Iran; Eye Research Center (M.A.), Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran; and Department of Medical Surgical Nursing (M.K.), School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Objectives: To evaluate the repeatability of anterior chamber depth (ACD) measurements by Orbscan and Pentacam imaging devices in different grades of keratoconus.

Methods: One examiner performed 3 consecutive ACD measurements with both devices on 74 eyes of 42 keratoconus patient. Repeatability was assessed using intrasession test-retest variability. Read More

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http://dx.doi.org/10.1097/ICL.0000000000000515DOI Listing
January 2019
1 Read
1.679 Impact Factor

Clinical presentation following photorefractive intrastromal cross-linking for myopic correction.

Indian J Ophthalmol 2018 07;66(7):993-994

Refractive Services, The Eye Foundation, Coimbatore, Tamil Nadu, India.

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http://dx.doi.org/10.4103/ijo.IJO_1227_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6032726PMC
July 2018
16 Reads

Comparison of the MyoRing implantation depth by mechanical dissection using PocketMaker microkeratome versus Melles hook via AS-OCT.

BMC Ophthalmol 2018 Jun 7;18(1):137. Epub 2018 Jun 7.

Department of Ophthalmology, Baqiyatallah University of Medical Sciences, Tehran, Iran.

Background: This paper seeks to evaluate the depth and outcomes of MyoRing implantation using two mechanical dissection procedures including: PocketMaker microkeratome in opposition to the Melles hook method.

Methods: This retrospective study was carried out on 39 eyes of 38 keratoconus patients (28 male and 10 female) with the mean age of [Formula: see text] years and had undergone MyoRing implantation by the two mentioned methods. The MyoRing was inserted into the corneal pocket which was made manually in 18 eyes (Melles hook group) or with PocketMaker microkeratome in 21 eyes (PocketMaker group). Read More

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http://dx.doi.org/10.1186/s12886-018-0806-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992749PMC
June 2018
11 Reads
1.075 Impact Factor

Topography-Based Removal of Corneal Epithelium for Keratoconus: A Novel and Customized Technique.

Cornea 2018 Jul;37(7):923-925

Imaging, Biomechanics and Mathematical Modeling Solutions Lab, Narayana Nethralaya Foundation, Bangalore, India.

Purpose: To report 3 cases of management of keratoconus with a novel topography-based removal of corneal epithelium in keratoconic eyes combined with corneal crosslinking.

Methods: Case report and technique description.

Results: Three eyes were imaged with the Sirius topographer (Schwind Eye-Tech-Solutions, Germany). Read More

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http://Insights.ovid.com/crossref?an=00003226-201807000-0002
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http://dx.doi.org/10.1097/ICO.0000000000001580DOI Listing
July 2018
3 Reads

Prevalence of glaucoma in Germany: results from the Gutenberg Health Study.

Graefes Arch Clin Exp Ophthalmol 2018 Sep 17;256(9):1695-1702. Epub 2018 May 17.

Department of Ophthalmology, University Medical Center Mainz, Langenbeckstr. 1, 55131, Mainz, Germany.

Purpose: To determine the prevalence of glaucoma according to the International Society for Geographical and Epidemiological Ophthalmology (ISGEO) classification in an adult German cohort.

Methods: The Gutenberg Health Study is a population-based, prospective cohort study in the Rhine-Main Region in mid-western Germany with a total of 15,010 participants. In this study, the first 5000 subjects with an age range between 35 and 74 years were included. Read More

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http://dx.doi.org/10.1007/s00417-018-4011-zDOI Listing
September 2018
41 Reads

Comparing Change in Anterior Curvature After Corneal Cross-linking Using Scanning-slit and Scheimpflug Technology.

Am J Ophthalmol 2018 Jul 3;191:129-134. Epub 2018 May 3.

USC Roski Eye Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA. Electronic address:

Purpose: To evaluate the correlation between anterior axial curvature difference maps following corneal cross-linking (CXL) for progressive keratoconus obtained from Scheimpflug-based tomography and Placido-based topography.

Design: Between-devices reliability analysis of randomized clinical trial data.

Methods: Corneal imaging was collected at a single-center institution preoperatively and at 3, 6, and 12 months postoperatively using Scheimpflug-based tomography (Pentacam; Oculus Inc, Lynnwood, Washington, USA) and scanning-slit, Placido-based topography (Orbscan II; Bausch & Lomb, Rochester, New York, USA) in patients with progressive keratoconus receiving standard protocol CXL (3 mW/cm for 30 minutes). Read More

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http://dx.doi.org/10.1016/j.ajo.2018.04.018DOI Listing
July 2018
1 Read
3.870 Impact Factor

[Femtosecond laser-assisted keratoplasty].

Orv Hetil 2018 Apr;159(17):671-676

Szemészeti Tanszék, Debreceni Egyetem, Általános Orvostudományi Kar Debrecen, Nagyerdei krt. 98., 4012.

Introduction And Aim: To present our results on femtosecond laser-assisted penetrating keratoplasty.

Patients And Method: Twenty-five eyes of 25 patients underwent surgery with the following indications: pseudophakic bullous keratopathy (n = 10), keratoconus (n = 4), corneal dystrophy (n = 5), corneal scar (n = 4), band keratopathy (n = 2). Trephination of both the donor and recipient corneas were performed with VisuMax femtosecond laser device (Carl Zeiss Meditec AG, Jena, Germany). Read More

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http://dx.doi.org/10.1556/650.2018.31035DOI Listing
April 2018
5 Reads

Acute hydrops with a 180-degree massive edematous cavern demonstrated by three dimensional view of anterior segment optical coherence tomography in a patient with pellucid marginal corneal degeneration, a case report.

BMC Ophthalmol 2018 Apr 13;18(1):92. Epub 2018 Apr 13.

Department of Ophthalmology, Osaka University Graduate School of Medicine, Room E7, Yamadaoka 2-2, Osaka, 565-0871, Japan.

Background: Pellucid marginal corneal degeneration is a non-inflammatory disorder complicated by severe inferior corneal thinning. The central portion of the cornea, consequently, appears to protrude outwards, decreasing vision by means of an irregular stigmatism. Additionally, acute hydrops can occur in case of Descemet's membrane rupture. Read More

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http://dx.doi.org/10.1186/s12886-018-0757-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899354PMC
April 2018
1 Read

Biological Lenticule Implantation for Correction of Hyperopia: An Ex Vivo Study in Human Corneas.

J Refract Surg 2018 Apr;34(4):245-252

Purpose: To evaluate changes in corneal tomography after stromal lenticule implantation ex vivo, with respect to the dependency of the lenticule thickness and implantation depth on the corneal curvature and the postoperative biomechanical strength at increased chamber pressure.

Methods: Twenty-eight human donor corneas underwent pocket implantation of refractive stromal lenticules. Four groups were created by the combination of two implantation depths (110 and 160 µm) and two lenticule thicknesses (95 µm = 4. Read More

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http://dx.doi.org/10.3928/1081597X-20180206-01DOI Listing
April 2018
2 Reads

Influence of soft contact lens material on corneal warpage: prevalence and time to resolution.

Can J Ophthalmol 2018 04 31;53(2):135-138. Epub 2017 Oct 31.

Faculty of Medicine, Saint-Joseph University, Beirut, Lebanon; Department of Ophthalmology, Hôtel-Dieu de France Hospital, Beirut, Lebanon.

Objective: Corneal warpage represents a reversible distortion of the corneal surface induced by soft contact lens (SCL) wear. The aim of the study is to assess the influence of SCL materials, age, wearing duration, cylindrical refraction, and spherical equivalence on the prevalence and time to resolution of corneal warpage.

Methods: This is an interventional prospective study in which SCL wearers volunteered to remove their SCLs and underwent, on each visit, a corrected distance visual acuity and anterior and posterior segment evaluation, along with keratometry measurement and corneal topography. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00084182173003
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http://dx.doi.org/10.1016/j.jcjo.2017.09.003DOI Listing
April 2018
2 Reads

Current perspectives on corneal collagen crosslinking (CXL).

Graefes Arch Clin Exp Ophthalmol 2018 Aug 6;256(8):1363-1384. Epub 2018 Apr 6.

Department of Anatomy, University of Otago, P.O. Box 913, 270 Great King Street, Dunedin, 9054, New Zealand.

Corneal collagen crosslinking has revolutionized the treatment of keratoconus and post-refractive corneal ectasia in the past decade. Corneal crosslinking with riboflavin and ultraviolet A is proposed to halt the progression of keratectasia. In the original "Conventional Dresden Protocol" (C-CXL), the epithelium is removed prior to the crosslinking process to facilitate better absorption of riboflavin into the corneal stroma. Read More

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http://link.springer.com/10.1007/s00417-018-3966-0
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http://dx.doi.org/10.1007/s00417-018-3966-0DOI Listing
August 2018
4 Reads

Long-term efficacy and safety after corneal collagen crosslinking in pediatric patients: Three-year follow-up.

Eur J Ophthalmol 2018 Jul 22;28(4):415-418. Epub 2018 Mar 22.

Research Department, Oftalmosalud Institute of Eyes, Lima, Peru.

Purpose: To evaluate the effectiveness of standard corneal collagen crosslinking for children with progressive keratoconus.

Methods: Prospective study including 26 eyes of 26 patients younger than 18 years old with progressive keratoconus at Oftalmosalud Instituto de Ojos, Lima, Peru. Standard epi-off corneal crosslinking was performed in all eyes between January 2012 and January 2013. Read More

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http://dx.doi.org/10.1177/1120672118760149DOI Listing
July 2018
3 Reads

Assessment of corneal backward light scattering in the healthy cornea and factors affecting corneal transparency.

Jpn J Ophthalmol 2018 May 16;62(3):335-341. Epub 2018 Mar 16.

Ulucanlar Eye Research Hospital, Ankara, Turkey.

Purpose: To quantify normative corneal optical density (COD) values of healthy individuals and to investigate alterations in the COD in relation to their ocular and demographic characteristics.

Study Design: Prospective, cross-sectional, and observational.

Methods: In total, 588 eyes from 588 healthy participants with clear corneas were consecutively enrolled. Read More

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http://dx.doi.org/10.1007/s10384-018-0584-7DOI Listing
May 2018
4 Reads

Validation of refraction and anterior segment parameters by a new multi-diagnostic platform (VX120).

J Optom 2018 Oct - Dec;11(4):242-251. Epub 2018 Mar 9.

Department of Optometry and Vision Science, Hadassah Academic College, Jerusalem, Israel. Electronic address:

Background: The VX120 (Visionix Luneau, France) is a novel multi-diagnostic platform that combines Hartmann-Shack based autorefraction, Placido-disk based corneal-topography and anterior segment measurements made with a stationary-Scheimpflug camera. We investigate the agreement between different parameters measured by the VX120 with accepted or gold-standard techniques to test if they are interchangeable, as well as to evaluate the repeatability and reproducibility.

Methods: The right-eyes of healthy subjects were included in the study. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18884296183000
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http://dx.doi.org/10.1016/j.optom.2017.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147758PMC
October 2018
8 Reads

The effect of orthokeratology on axial length elongation in children with myopia: Contralateral comparison study.

Authors:
Miri Na Aeri Yoo

Jpn J Ophthalmol 2018 May 9;62(3):327-334. Epub 2018 Mar 9.

Department of Ophthalmology, Saevit Eye Hospital, 1065, Jungang-ro, Ilsandong-gu, Goyang, Gyeonggi-do, 10447, Republic of Korea.

Purpose: To evaluate the effectiveness of the orthokeratology (OK) lens slowing myopic progression compared with no intervention in pediatric eyes METHODS: A retrospective review of medical records was performed on 45 monocular myopic subjects 7 to 13 years of age who were treated with monocular ortho-k lens and followed-up for more than 12 months. The monocular myopia in the subjects' eyes was -0.75 to -4. Read More

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http://dx.doi.org/10.1007/s10384-018-0573-xDOI Listing
May 2018
5 Reads

Predictability of Tunnel Depth for Intrastromal Corneal Ring Segments Implantation Between Manual and Femtosecond Laser Techniques.

J Refract Surg 2018 Mar;34(3):188-194

Purpose: To compare the predictability of intrastromal tunnel depth creation for intrastromal corneal ring segments (ICRS) implantation between manual dissection and femtosecond laser using a high-resolution anterior segment optical coherence tomography (AS-OCT).

Methods: This multicenter study included patients with keratoconus who had Ferrara-type ICRS implantation at Hospital de Braga using manual dissection and at the Fernandez-Vega Ophthalmological Institute using the femtosecond laser technique. The intended depth of implantation was compared to the achieved postoperative ICRS depth of each case, measured using a swept-source AS-OCT (CASIA SS-1000; Tomey Corporation, Nagoya, Japan) at three points (proximal, central, and distal end of the implant). Read More

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http://dx.doi.org/10.3928/1081597X-20180108-01DOI Listing
March 2018
4 Reads

Cornea and anterior eye assessment with placido-disc keratoscopy, slit scanning evaluation topography and scheimpflug imaging tomography.

Authors:
Raul Martin

Indian J Ophthalmol 2018 Mar;66(3):360-366

Departamento de Física Teórica, Atómica y Óptica, Universidad de Valladolid; Instituto Universitario de Oftalmobiología Aplicada (IOBA), Universidad de Valladolid; IOBA Eye Institute, School of Optometry, University of Valladolid, Valladolid, Spain; Faculty of Health and Human Sciences, Plymouth University, PL6 8BH Plymouth, United Kingdom.

Current corneal assessment technologies make the process of corneal evaluation extremely fast and simple and several devices and technologies allow to explore and to manage patients. The purpose of this special issue is to present and also to update in the evaluation of cornea and ocular surface and this second part, reviews a description of the corneal topography and tomography techniques, providing updated information of the clinical recommendations of these techniques in eye care practice. Placido-based topographers started an exciting anterior corneal surface analysis that allows the development of current corneal tomographers that provide a full three-dimensional reconstruction of the cornea including elevation, curvature, and pachymetry data of anterior and posterior corneal surfaces. Read More

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http://dx.doi.org/10.4103/ijo.IJO_850_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859588PMC
March 2018
4 Reads

Correlation between central stromal demarcation line depth and changes in K values after corneal cross-linking (CXL).

Graefes Arch Clin Exp Ophthalmol 2018 Apr 23;256(4):759-764. Epub 2018 Feb 23.

Department of Ophthalmology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

Purpose: A stromal demarcation line (DL) after corneal cross-linking (CXL) has lately been suggested as a surrogate parameter for the success of CXL. The aim of this study was to investigate the correlation between depth of the central DL 1 month and the change in K values 12 months after CXL.

Methods: Treatment-naive subjects with keratoconus were treated using an accelerated CXL protocol [A-CXL(9*10)]. Read More

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http://dx.doi.org/10.1007/s00417-018-3922-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856899PMC
April 2018
7 Reads

Optical Properties Influence Visual Cortical Functional Resolution After Cataract Surgery and Both Dissociate From Subjectively Perceived Quality of Vision.

Invest Ophthalmol Vis Sci 2018 02;59(2):986-994

Faculty of Medicine of the University of Coimbra, Coimbra, Portugal.

Purpose: To investigate the relation between optical properties, population receptive fields (pRFs), visual function, and subjectively perceived quality of vision after cataract surgery.

Methods: The study includes 30 patients who had recently undergone bilateral sequential cataract surgery. We used functional magnetic resonance imaging and pRF modelling methods to assess pRF sizes across visual cortical regions (V1-V3). Read More

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http://dx.doi.org/10.1167/iovs.17-22321DOI Listing
February 2018

[Analysis on the role of Sirius combined topography and tomography system in screening for suspect keratoconus].

Zhonghua Yan Ke Za Zhi 2018 Jan;54(1):33-38

Department of Ophthalmology, Peking University Third Hospital, Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Beijing 100191, China.

To evaluate the role of Sirius combined topography and tomography system in screening for suspect keratoconus among the corneal refractive surgery candidates. Retrospective case series study. Eight hundred and sixteen consecutive ametropic patients (1 632 eyes) who underwent routine examinations before corneal refractive surgery at Peking University Third Hospital from January 2016 to September 2016 were reviewed. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0412-4081.2018.01.007DOI Listing
January 2018
12 Reads

Femtosecond Laser-Assisted Small Incision Endokeratophakia Using a Xenogeneic Lenticule in Rhesus Monkeys.

Cornea 2018 Mar;37(3):354-361

Zhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Sun Yat-Sen University, Guangzhou, China.

Purpose: To evaluate the feasibility and safety of xenogeneic endokeratophakia in rhesus monkeys and to explore the effects of a concave lenticule on refractive power.

Methods: Three adult New Zealand white rabbits and 6 healthy rhesus monkeys were used. The xenogenic concave grafts were created from the rabbits using a modified small incision lenticule extraction technique; after being cryopreserved in glycerol for 1 week, the grafts were implanted into the monkey recipient corneas. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001470DOI Listing
March 2018
4 Reads

An Early Finding of Keratoconus: Increase in Corneal Densitometry.

Cornea 2018 May;37(5):580-586

Ophthalmology Department, Ulucanlar Eye Training and Research Hospital, Ankara, Turkey.

Purpose: To investigate the corneal densitometry in subclinical keratoconus with normal elevation and pachymetric parameters.

Methods: Patients with clinical keratoconus in one eye and subclinical keratoconus in the fellow eye were identified. The study group was selected from patients with subclinical keratoconus who showed normal results from topographic and Belin-Ambrósio Enhanced Ectasia Display III (BAD) analysis (Kmean <47. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001537DOI Listing
May 2018
3 Reads

Interface healing and its correlation with visual recovery and quality of vision following small incision lenticule extraction.

Indian J Ophthalmol 2018 Feb;66(2):212-218

Department of Phacorefractive, Nethradhama Superspeciality Eye Hospital, Bengaluru, Karnataka, India.

Purpose: To study the time course of interface healing and its correlation with visual acuity, modulation transfer function (MTF), and aberrations after myopic small-incision lenticule extraction (SMILE) correction.

Methods: Seventy-eight eyes of 78 patients (1 eye per patient) with a mean age of 25.7 years and mean spherical equivalent (SE) of -3. Read More

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http://dx.doi.org/10.4103/ijo.IJO_775_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819097PMC
February 2018
3 Reads

Clinical signs in cornea and ocular surface.

Indian J Ophthalmol 2018 Feb;66(2):202-206

Department of Ophthalmology, Krishna Institute of Medical Sciences, Hyderabad, Telangana, India.

A careful examination of cornea and ocular surface eliciting the basic signs will help a clinician toward an accurate diagnosis. Flipping the upper lid or pulling the lower lid to look at the inferior fornix may help to pick up any subtle clinical sign. Meticulous documentation by diffuse and slit view will help in following up the disease. Read More

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http://dx.doi.org/10.4103/ijo.IJO_716_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819095PMC
February 2018
1 Read

Cornea and anterior eye assessment with slit lamp biomicroscopy, specular microscopy, confocal microscopy, and ultrasound biomicroscopy.

Authors:
Raul Martin

Indian J Ophthalmol 2018 Feb;66(2):195-201

Departamento de Física Teórica, Atómica y Óptica, Universidad de Valladolid; Instituto Universitario de Oftalmobiología Aplicada, Universidad de Valladolid; School of Optometry, IOBA Eye Institute, University of Valladolid, 47011 Valladolid, Spain; Faculty of Health and Human Sciences, Plymouth University, PL6 8BH Plymouth, United Kingdom.

Current corneal assessment technologies make the process of corneal evaluation extremely fast and simple, and several devices and technologies show signs that help in identification of different diseases thereby, helping in diagnosis, management, and follow-up of patients. The purpose of this review is to present and update readers on the evaluation of cornea and ocular surface. This first part reviews a description of slit lamp biomicroscopy (SLB), endothelial specular microscopy, confocal microscopy, and ultrasound biomicroscopy examination techniques and the second part describes the corneal topography and tomography, providing up-to-date information on the clinical recommendations of these techniques in eye care practice. Read More

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http://dx.doi.org/10.4103/ijo.IJO_649_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819094PMC
February 2018

Evaluation of Corneal Parameters with Dual Scheimpflug Imaging in Patients with Systemic Sclerosis.

Curr Eye Res 2018 04 16;43(4):451-454. Epub 2018 Jan 16.

a Department of Ophthalmology , Federal University of Rio de Janeiro , Rio de Janeiro , Brazil.

Purpose: To evaluate the cornea of systemic sclerosis (SSc) patients with Dual Scheimpflug Imaging.

Methods: Twenty consecutive SSc patients and 20 age and sex matched controls were enrolled in this cross-sectional study. Corneal measurements were acquired by dual Scheimpflug analyzer. Read More

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http://dx.doi.org/10.1080/02713683.2017.1414855DOI Listing
April 2018
1 Read

Applications of corneal topography and tomography: a review.

Clin Exp Ophthalmol 2018 Mar 11;46(2):133-146. Epub 2018 Jan 11.

Department of Ophthalmology & Visual Sciences, The Chinese University of Hong Kong, Hong Kong.

Corneal imaging is essential for diagnosing and management of a wide variety of ocular diseases. Corneal topography is used to characterize the shape of the cornea, specifically, the anterior surface of the cornea. Most corneal topographical systems are based on Placido disc that analyse rings that are reflected off the corneal surface. Read More

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http://doi.wiley.com/10.1111/ceo.13136
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http://dx.doi.org/10.1111/ceo.13136DOI Listing
March 2018
9 Reads

Early visual outcomes and optical quality after femtosecond laser small-incision lenticule extraction for myopia and myopic astigmatism correction of over -10 dioptres.

Acta Ophthalmol 2018 May 18;96(3):e341-e346. Epub 2017 Dec 18.

Department of Ophthalmology, Myopia Key Laboratory of the Health Ministry, Eye and ENT Hospital of Fudan University, Shanghai, China.

Purpose: To investigate early visual and refractive outcomes, corneal stability and optical quality after femtosecond laser small-incision lenticule extraction (SMILE) for treating myopia and myopic astigmatism over -10 D.

Methods: Thirty eyes (30 patients) with myopia and myopic astigmatism of over -10 D were treated with VisuMax femtosecond laser (version 3.0; Carl Zeiss Meditec AG, Jena, Germany). Read More

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http://dx.doi.org/10.1111/aos.13609DOI Listing
May 2018
19 Reads

Management and Outcomes of Retained Lenticules and Lenticule Fragments Removal After Failed Primary SMILE: A Case Series.

J Refract Surg 2017 Dec;33(12):848-853

Purpose: To describe the management of and report the outcomes following the removal of retained lenticules or lenticule fragments after a complicated small incision lenticule extraction (SMILE).

Methods: Three patients were referred for consultation due to intraoperative complications during SMILE. In case 1, the lenticule was torn during extraction and a central fragment was retained in the pocket. Read More

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http://dx.doi.org/10.3928/1081597X-20171004-01DOI Listing
December 2017
23 Reads

Comparison of Methodologies Using Estimated or Measured Values of Total Corneal Astigmatism for Toric Intraocular Lens Power Calculation.

J Refract Surg 2017 Dec;33(12):794-800

Purpose: To compare the prediction error in the calculation of toric intraocular lenses (IOLs) associated with methods that estimate the power of the posterior corneal surface (ie, Barrett toric calculator and Abulafia-Koch formula) with that of methods that consider real measures obtained using Scheimpflug imaging: a software that uses vectorial calculation (Panacea toric calculator: http://www.panaceaiolandtoriccalculator.com) and a ray tracing software (PhacoOptics, Aarhus Nord, Denmark). Read More

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http://dx.doi.org/10.3928/1081597X-20171004-03DOI Listing
December 2017
59 Reads

Outcomes of Corneal Cross-Linking Correlate With Cone-Specific Lysyl Oxidase Expression in Patients With Keratoconus.

Cornea 2018 03;37(3):369-374

Singapore Eye Research Institute, Singapore.

Purpose: To evaluate the correlation of visual and keratometry outcomes after corneal cross-linking (CXL) in patients with keratoconus with cone epithelium-specific gene expression levels.

Methods: Corneal epithelium was obtained from 35 eyes that underwent accelerated CXL (KXLII, 9 mW/cm for 10 min). Using corneal topography, epithelium over the cone and periphery was obtained separately from each subject. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001478DOI Listing
March 2018
20 Reads

Advanced anterior segment imaging in keratoconus: a review.

Clin Exp Ophthalmol 2018 Mar 21;46(2):122-132. Epub 2017 Dec 21.

Department of Ophthalmology, New Zealand National Eye Centre, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.

Advances in anterior segment imaging have enhanced our ability to detect keratoconus in its early stages and characterize the pathologic changes that occur. Computerized corneal tomography has elucidated the alterations in shape of the anterior and posterior corneal surfaces and alterations in thickness as the disease progresses. Automated screening indices such as the keratoconus screening index were developed to assist in detecting keratoconus in suspicious cases. Read More

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http://dx.doi.org/10.1111/ceo.13108DOI Listing
March 2018
15 Reads