590 results match your criteria Corneal Abrasion


Acute tobacco smoke exposure exacerbates the inflammatory response to corneal wounds in mice via the sympathetic nervous system.

Commun Biol 2019 24;2:33. Epub 2019 Jan 24.

1International Ocular Surface Research Center, Institute of Ophthalmology, Key Laboratory for Regenerative Medicine of the Ministry of Education, Jinan University, Guangzhou, China.

Exposure to tobacco smoke is a major public health concern that can also affect ophthalmic health. Based on previous work demonstrating the important role of the sympathetic nervous system (SNS) in corneal wound repair, we postulated that acute tobacco smoke exposure (ATSE) may act through the SNS in the impairment of corneal wound repair. Here we find that ATSE rapidly increases the markers of inflammatory response in normal corneal limbi. Read More

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http://dx.doi.org/10.1038/s42003-018-0270-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345828PMC
January 2019

Corneal and conjunctival injury seen in urgent care centres in Israel.

Ophthalmic Physiol Opt 2019 Jan;39(1):46-52

Department of Optometry, Hadassah Academic College, Jerusalem, Israel.

Purpose: Corneal and conjunctival injuries (CCI) comprise a large portion of the cases presenting to hospital-based emergency departments (ED) with ocular involvement. Urgent Care Centres (UCC) offer community based emergency care at lower cost than hospital-based emergency departments (ED) and with greater temporal convenience than primary care office settings. While CCI prevalence and treatment at hospital-based EDs has been well studied, this is the first report, to our knowledge, on CCI demographics and aetiology presenting to UCCs. Read More

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http://doi.wiley.com/10.1111/opo.12600
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http://dx.doi.org/10.1111/opo.12600DOI Listing
January 2019
5 Reads

Prevalence, habits and outcomes of using contact lenses among medical students.

Pak J Med Sci 2018 Nov-Dec;34(6):1429-1434

Lina Reda, Intern, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.

Objectives: To determine the prevalence, reasons of use, reported hygienic practices, and complications related to CLs' usage, and to assess awareness of medical students about CLs' hygienic behaviours, King Abdulaziz University (KAU), Jeddah, Saudi Arabia.

Methods: A cross-sectional design was done. A multi-stage stratified random sampling was utilized to select 536 medical students. Read More

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http://dx.doi.org/10.12669/pjms.346.16260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290225PMC
December 2018

Periocular Manifestations of Afatinib Therapy.

Ophthalmic Plast Reconstr Surg 2019 Jan/Feb;35(1):e12-e13

Oxford University Hospital, Headley Way, Headington, Oxford, United Kingdom.

Epidermal growth factor receptor tyrosine kinase inhibitor therapy has been increasingly employed in the treatment of a variety of tumors. The authors report the rarely documented side effect of trichiasis with the use of Afatinib in a patient with spinal chordoma and review-related literature. A 67-year-old lady was referred to the oculoplastic service with a 3-month history of ocular irritation and pain associated with blurred vision. Read More

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http://dx.doi.org/10.1097/IOP.0000000000001277DOI Listing
December 2018
1 Read

Antibiotic-Induced Dysbiosis of Gut Microbiota Impairs Corneal Nerve Regeneration by Affecting CCR2-Negative Macrophage Distribution.

Am J Pathol 2018 Dec;188(12):2786-2799

International Ocular Surface Research Center and Institute of Ophthalmology, Jinan University Medical School, Guangzhou, People's Republic of China; Key Laboratory for Regenerative Medicine, Ministry of Education, Jinan University, Guangzhou, People's Republic of China; Department of Ophthalmology, Henan Provincial People's Hospital, Zhengzhou, People's Republic of China; Section of Leukocyte Biology, Department of Pediatrics, Children's Nutrition Research Center, Baylor College of Medicine, Houston, Texas. Electronic address:

Although antibiotics are useful, they can also bring negative effects. We found that antibiotic-treated mice exhibit an alteration in the gene expression profile of corneal tissues and a decrease in corneal nerve density. During corneal wound healing, antibiotic treatment was found to impair corneal nerve regeneration, an effect that could be largely reversed by reconstitution of the gut microbiota via fecal transplant. Read More

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http://dx.doi.org/10.1016/j.ajpath.2018.08.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284554PMC
December 2018
2 Reads
4.591 Impact Factor

24-Hour Intraocular Pressure Control with Fixed-dose Combination Brinzolamide 1%/Brimonidine 0.2%: A Multicenter, Randomized Trial.

Ophthalmology 2018 Nov 4. Epub 2018 Nov 4.

Novartis Pharmaceuticals Corporation, Fort Worth, Texas.

Purpose: To determine the intraocular pressure (IOP)-lowering effect of fixed-combination brinzolamide 1%/brimonidine 0.2% (BBFC) over a 24-hour period.

Design: Prospective, multicenter, double-masked, parallel-group clinical trial conducted at 16 academic and nonacademic sites in the United States. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01616420183046
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http://dx.doi.org/10.1016/j.ophtha.2018.10.040DOI Listing
November 2018
15 Reads

Eye Protection in Liver Transplantation Patients Under General Anesthesia.

Transplant Proc 2018 Nov 19;50(9):2651-2653. Epub 2018 Mar 19.

Department of Anesthesiology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan. Electronic address:

Background: Opsite (Smith & Nephew, Hull, UK) is widely used in wound care but its use in eye protection against corneal abrasion during major surgery is rarely reported. The purpose of the current study is to compare the effectiveness of using Opsite in eye protection with either wet gauze alone or with wet gauze following application of eye ointment in patients undergoing living donor liver transplantation (LDLT).

Methods: This is a prospective, double-blinded, randomized controlled trial. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00411345183047
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http://dx.doi.org/10.1016/j.transproceed.2018.02.202DOI Listing
November 2018
13 Reads

Toy gun eye injuries - eye protection needed Helsinki ocular trauma study.

Acta Ophthalmol 2018 Nov 2. Epub 2018 Nov 2.

University of Helsinki and Helsinki University Eye Hospital, Helsinki, Finland.

Purpose: We report the epidemiology, findings, treatment, long-term outcome and use of resources for eye injuries caused by toy guns in southern Finland.

Methods: All new patients injured by toy guns in one year (2011-2012) and treated at Helsinki University Eye Hospital were included. Follow-ups occurred at 3 months and 5 years. Read More

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http://dx.doi.org/10.1111/aos.13948DOI Listing
November 2018
1 Read

Novel Dexamethasone Sodium Phosphate Treatment (DSP-Visulex) for Noninfectious Anterior Uveitis: A Randomized Phase I/II Clinical Trial.

Curr Eye Res 2019 Feb 15;44(2):185-193. Epub 2018 Nov 15.

a Aciont Inc , Salt Lake City , UT , USA.

Purpose: Frequent steroid drops represent a challenge in patient compliance. This study evaluated the safety and efficacy of 5 minute topical dexamethasone sodium phosphate-Visulex (DSP-Visulex) treatment regimen (two applications on the first week then weekly after) compared to daily prednisolone acetate 1% (PA) for noninfectious anterior uveitis.

Materials And Methods: Forty-four patients were randomized to 8% DSP-Visulex with placebo eye drops (8% group, n = 14), 15% DSP-Visulex with placebo eye drops (15% group, n = 15), or Vehicle-Visulex with PA eye drops (PA group, n = 15). Read More

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https://www.tandfonline.com/doi/full/10.1080/02713683.2018.1
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http://dx.doi.org/10.1080/02713683.2018.1540707DOI Listing
February 2019
51 Reads

Prospective analysis of emergency ophthalmic referrals in a Canadian tertiary teaching hospital.

Can J Ophthalmol 2018 Oct 1;53(5):497-502. Epub 2018 Mar 1.

UBC Department of Ophthalmology and Visual Sciences, Vancouver, B.C.; Vancouver General Hospital Eye Care Centre, Vancouver, B.C.

Objective: This study was conducted to analyze data from emergency ophthalmology referrals after hours from different hospitals to identify the most common pathologies and compare accuracy of diagnoses. Additionally, examination findings, including visual acuity (VA), intraocular pressure (IOP), and pupils from referring service and ophthalmic examination, were compared to assess agreement.

Design: This was a prospective study that reviewed information collected from referring services to the emergency on-call ophthalmology service and compared it with ophthalmic examination between February 2017 and July 2017. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00084182173106
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http://dx.doi.org/10.1016/j.jcjo.2018.01.008DOI Listing
October 2018
5 Reads

Case Report: Penetrating Corneal Injury Under an Intact Laser-assisted in Situ Keratomileusis Flap.

Optom Vis Sci 2018 Nov;95(11):1083-1086

University of Minnesota, Minneapolis, Minnesota

Significance: As the prevalence of post-laser-assisted in situ keratomileusis (LASIK) patients rises, recognition of possible traumatic complications and their management in this population becomes increasingly relevant. Penetrating injuries and intraocular foreign bodies are possible in post-LASIK corneas despite an intact anterior corneal surface. However, with prompt recognition and treatment, excellent visual recovery can be achieved. Read More

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http://dx.doi.org/10.1097/OPX.0000000000001297DOI Listing
November 2018
1 Read

Safety and Tolerability of Overdosed Artificial Tears by Abraded Rabbit Corneas.

J Ocul Pharmacol Ther 2018 Oct 12. Epub 2018 Oct 12.

1 SANTEN SAS, Novagali Innovation Center , Evry Cedex, France .

Purpose: Preservative-free cationic emulsion-based artificial tear (AT) is an innovative eye drop based on the Novasorb technology with cetalkonium chloride (CKC) as the cationic agent. The cationic emulsion Cationorm is designed for the management of mild-to-moderate dry eye disease (DED) patients that present cornea epithelium alterations. The aim of the present study was to evaluate the safety and tolerability of overdosed ATs by altered corneal epithelium in vivo and assess the usefulness of the ex vivo eye irritation test (EVEIT) as a predictive alternate toxicity test method. Read More

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https://www.liebertpub.com/doi/10.1089/jop.2018.0040
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http://dx.doi.org/10.1089/jop.2018.0040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302909PMC
October 2018
3 Reads

Eye injuries in children - incidence and outcomes: An observational study at a dedicated children's eye casualty.

Eur J Ophthalmol 2018 Oct 1:1120672118803512. Epub 2018 Oct 1.

1 Moorfields Eye Hospital, London, UK.

Purpose: Trauma is an important cause of visual loss in children and may affect their quality of life. Prevention and legislation can reduce the incidence of trauma, and appropriate and timely treatment can improve prognosis. We aimed to describe incidence of eye injuries in children and the adherence to national and local management guidelines. Read More

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http://dx.doi.org/10.1177/1120672118803512DOI Listing
October 2018
1 Read

Oval sign: A retained bee stinger.

Indian J Ophthalmol 2018 Oct;66(10):1466-1467

Tej Kohli Cornea Institute, L V Prasad Eye Institute, Hyderabad, Telangana, India.

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http://www.ijo.in/text.asp?2018/66/10/1466/242015
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http://dx.doi.org/10.4103/ijo.IJO_465_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173003PMC
October 2018
5 Reads

Rare chemical injuries: a case of ocular superglue instillation in Port Harcourt.

Int Med Case Rep J 2018 7;11:209-212. Epub 2018 Sep 7.

Department of Ophthalmology, University of Port Harcourt Teaching Hospital, Rivers State, Nigeria,

Background: Ocular superglue injury is uncommon all over the world.

Aim: To report a case of self-inflicted accidental ocular superglue injury.

Methods: A case of ocular injury is described in a 29-year-old adult, following inadvertent instillation of superglue instead of a prescribed steroid ointment into the right eye, in the dark. Read More

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http://dx.doi.org/10.2147/IMCRJ.S170601DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135065PMC
September 2018

Effectiveness of corneal abrasion prevention interventions for adults undergoing general anesthesia for more than one hour: a systematic review protocol.

JBI Database System Rev Implement Rep 2018 Sep;16(9):1785-1790

School of Nursing, Louisiana State University Health Sciences Center, New Orleans, USA.

Review Question: The question of this review is: what is the effectiveness of eye lubrication, tape and/or a combination of these interventions in preventing corneal abrasions in adult patients aged 18 and over undergoing general anesthesia for more than one hour? Read More

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http://dx.doi.org/10.11124/JBISRIR-2017-003670DOI Listing
September 2018
1 Read

Acute hyperalgesia and delayed dry eye after corneal abrasion injury.

Pain Rep 2018 Jul-Aug;3(4):e664. Epub 2018 Jun 20.

Department of Physiology and Pharmacology, Oregon Health & Science University, Portland, OR, USA.

Introduction: Corneal nerves mediate pain from the ocular surface, lacrimation, and blinking, all of which protect corneal surface homeostasis and help preserve vision. Because pain, lacrimation and blinking are rarely assessed at the same time, it is not known whether these responses and their underlying mechanisms have similar temporal dynamics after acute corneal injury.

Methods: We examined changes in corneal nerve density, evoked and spontaneous pain, and ocular homeostasis in Sprague-Dawley male rats after a superficial epithelial injury with heptanol. Read More

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http://dx.doi.org/10.1097/PR9.0000000000000664DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085140PMC
June 2018
16 Reads

Ocular complications of severe corneal abrasions after cosmetic blepharopigmentation.

J Cosmet Laser Ther 2018 Aug 17:1-3. Epub 2018 Aug 17.

a Department of Ophthalmology , Erciyes University Faculty of Medicine , Kayseri , Turkey.

A 53-year-old woman with hemiparesis and poor dexterity, underwent cosmetic blepharopigmentation on the both upper eyelids in the dermatology clinic of a private hospital. She was not asked for any information on her medical history and no informed consent was obtained and the procedure was performed without any protective ocular shields. The patient experienced severe lacrimation, discomfort, and increased sensitivity to light during and after the procedure. Read More

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http://dx.doi.org/10.1080/14764172.2018.1511911DOI Listing
August 2018
2 Reads

Corneal endothelial decompensation due to airbag injury.

Int Ophthalmol 2018 Oct 14;38(5):2171-2174. Epub 2018 Aug 14.

Department of Ophthalmology, All India Institute of Medical Sciences, Rishikesh, 249204, India.

Purpose: We report a case of localized endothelial decompensation due to airbag deployment during a motor vehicle accident.

Case Report: A middle-aged woman involved in a motor vehicle accident presented with diminution of vision in left eye. Initial ocular examination revealed corneal abrasion, localized central corneal edema and mild anterior chamber reaction. Read More

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http://dx.doi.org/10.1007/s10792-018-0999-7DOI Listing
October 2018

Corneal Epithelial Abrasion with Ocular Burr As a Model for Cornea Wound Healing.

J Vis Exp 2018 07 10(137). Epub 2018 Jul 10.

Helsinki Institute of Life Science, Institute of Biotechnology, University of Helsinki; School of Medicine and Institute for Science and Technology in Medicine, Keele University;

The murine cornea provides an excellent model to study wound healing. The cornea is the outermost layer of the eye, and thus is the first defense to injury. In fact, the most common type of eye injury found in clinic is a corneal abrasion. Read More

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http://dx.doi.org/10.3791/58071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126453PMC
July 2018
9 Reads

Alcohol delamination of the corneal epithelium for recurrent corneal erosion syndrome.

Int J Ophthalmol 2018 18;11(7):1129-1131. Epub 2018 Jul 18.

Education and Research Centre, Royal Victoria Eye and Ear Hospital, Dublin D02XK51, Ireland.

Aim: To evaluate the outcomes of alcohol delamination (ALD) of the corneal epithelium for the treatment of recurrent corneal erosion syndrome (RCES) and to implement a standardized treatment protocol for this condition utilizing evidence based practice and the findings of an internal audit.

Methods: A retrospective analysis of 42 eyes of 40 patients diagnosed with RCES who were treated with ALD between January 2006 and March 2016 was conducted. Patients had 20% alcohol applied to the cornea with the use of a well for 40s. Read More

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http://dx.doi.org/10.18240/ijo.2018.07.09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048330PMC

"Eye Dropping"-A Case Report of Transconjunctival Lysergic Acid Diethylamide Drug Abuse.

Cornea 2018 Oct;37(10):1324-1325

Department of Ophthalmology, New York University School of Medicine, New York, NY.

Purpose: To report a case of bilateral toxic corneal and conjunctival epitheliopathy secondary to administration of filter paper impregnated with lysergic acid diethylamide (LSD) in the inferior conjunctival fornices.

Methods: This is a single case report of an 18-year-old man who presented to the emergency department with acute, bilateral eye pain and redness of 24 hours. The patient admitted to placing folded strips of blotting paper impregnated with LSD into the inferior fornices of his eyes the previous night. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001692DOI Listing
October 2018
3 Reads

The mouse autonomic nervous system modulates inflammation and epithelial renewal after corneal abrasion through the activation of distinct local macrophages.

Mucosal Immunol 2018 09 9;11(5):1496-1511. Epub 2018 Jul 9.

International Ocular Surface Research Center, Institute of Ophthalmology, Key Laboratory for Regenerative Medicine, Jinan University Medical School, Guangzhou, China.

Inflammation and reepithelialization after corneal abrasion are critical for the rapid restoration of vision and the prevention of microbial infections. However, the endogenous regulatory mechanisms are not completely understood. Here we report that the manipulation of autonomic nervous system (ANS) regulates the inflammation and healing processes. Read More

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http://dx.doi.org/10.1038/s41385-018-0031-6DOI Listing
September 2018
27 Reads
7.374 Impact Factor

Ocular surface injury after shoulder surgery in the beach-chair position.

Int Orthop 2018 Dec 26;42(12):2891-2895. Epub 2018 Jun 26.

Shoulder & Elbow Clinic, Department of Orthopaedic Surgery, College of Medicine, Kyung Hee University, Seoul, Republic of Korea.

Purpose: During shoulder surgery in the beach-chair position, head fixation can sometimes cause rare complications. The authors share their experience in treating ocular injury due to improper head fixation during surgery in the beach-chair position.

Methods: The study investigated consecutively 6075 patients who underwent shoulder surgery in the beach-chair position between March 2007 and March 2016, those patients who saw an ophthalmologist with a complaint of post-operative ocular discomfort. Read More

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http://dx.doi.org/10.1007/s00264-018-4044-2DOI Listing
December 2018

Management of traumatic corneal abrasion by a sample of practicing ophthalmologists in Saudi Arabia.

Saudi J Ophthalmol 2018 Apr-Jun;32(2):105-109. Epub 2017 Oct 31.

Department of Ophthalmology, College of Medicine, King Saud University, Saudi Arabia.

Purpose: Corneal epithelial defect (CED) is a common medical emergency condition involving loss of surface epithelial layer of the cornea. The aim of the study is to explore the practice patterns of ophthalmologists in management of traumatic CED in Saudi Arabia and to assess the variance in clinical practice from the established clinical practice guidelines.

Methods: A Survey based study at King Abdulaziz University Hospital between March 2015 and January 2016. Read More

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http://dx.doi.org/10.1016/j.sjopt.2017.10.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010595PMC
October 2017
1 Read

High fat diet induces pre-type 2 diabetes with regional changes in corneal sensory nerves and altered P2X7 expression and localization.

Exp Eye Res 2018 10 5;175:44-55. Epub 2018 Jun 5.

Boston University School of Medicine, 80 E. Concord St. Boston, MA, 02118, USA. Electronic address:

Type 2 diabetes is one of the leading pathologies that increases the risk of improper wound healing. Obesity has become a major risk factor for this disease that is now considered to be the 4th highest cause of preventable blindness according to the World Health Organization. The cornea is the most densely innervated structure in the human body and senses even the slightest injury. Read More

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http://dx.doi.org/10.1016/j.exer.2018.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217827PMC
October 2018
6 Reads

Clinical and Histological Characterization of Toxic Keratopathy From Depatuxizumab Mafodotin (ABT-414), an Antibody-Drug Conjugate: [RETRACTED].

Cornea 2018 May 23. Epub 2018 May 23.

Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, MN.

Purpose: To report the first histological characterization of microcyst-like epithelial keratopathy (MEK) associated with depatuxizumab mafodotin (ABT-414).

Methods: Case report.

Results: A 35-year-old man with glioblastoma multiforme participating in a phase III trial of the antibody-drug conjugate ABT-414 developed a large corneal abrasion from complications of MEK. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001635DOI Listing
May 2018
2 Reads

Recurrent corneal erosion caused by retained sutures in blepharoplasty.

Int Ophthalmol 2018 Apr 27. Epub 2018 Apr 27.

Department of Ophthalmology, National Taiwan University Hospital, College of Medicine, National Taiwan University, 7, Chung-Shan South Road, Taipei, Taiwan.

Purpose: To present recurrent corneal erosion (RCE) caused by late suture exposure after blepharoplasty.

Methods: Four patients who have unilateral RCE were found to have previous blepharoplasty. The RCE was associated with late suture exposure. Read More

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http://dx.doi.org/10.1007/s10792-018-0936-9DOI Listing
April 2018
4 Reads

[Fungal keratitis: A 5-year monocentric retrospective study on Reunion Island].

J Fr Ophtalmol 2018 Apr 19;41(4):321-325. Epub 2018 Apr 19.

Service de bactériologie-virologie-parasitologie, CHU de La Réunion, BP 350, 97448 Saint-Pierre, Réunion.

Objectives: Fungal keratitis is rare in France, but could be a severe sight-threatening condition. Here, we aimed to describe the epidemiology of fungal keratitis in Réunion Island.

Methods: In a retrospective study, we analyzed 13 culture-proven keratitis episodes, occurred between January 2013 and July 2017 in the ophthalmology ward of a University Hospital, Saint-Pierre. Read More

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http://dx.doi.org/10.1016/j.jfo.2017.09.015DOI Listing
April 2018
2 Reads

Ophthalmologic Complications Associated With Oculofacial Plastic and Esthetic Surgeries.

J Craniofac Surg 2018 Jul;29(5):1208-1211

Department of Ophthalmology, Kim's Eye Hospital, Myung-Gok Eye Research Institute, Konyang University College of Medicine.

Purpose: To assess the ophthalmologic complications after oculofacial plastic and esthetic surgeries, including their incidence and management.

Methods: A retrospective study was performed on 110 patients who presented with ocular complications followed by oculofacial plastic and esthetic surgeries from January 2014 to December 2015. The incidence and management of complications after each surgery or procedure were analyzed. Read More

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http://dx.doi.org/10.1097/SCS.0000000000004515DOI Listing
July 2018
10 Reads

Ocular complications following treatment in the Postnatal Growth and Retinopathy of Prematurity (G-ROP) Study.

J AAPOS 2018 Apr 14;22(2):128-133. Epub 2018 Mar 14.

Scheie Eye Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia; The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

Purpose: To determine the prevalence of treatment-related ocular complications and disease progression following treatment for retinopathy of prematurity (ROP).

Methods: This was a retrospective cohort study of eyes treated for ROP at 29 North American neonatal intensive care units in the Postnatal Growth and ROP (G-ROP) Study. Data from the time of treatment through 15 months were abstracted from medical records by certified data collectors. Read More

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http://dx.doi.org/10.1016/j.jaapos.2017.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915915PMC
April 2018
6 Reads

Tetracaine Challenges Old Dogma for Emergency Department Management of Corneal Abrasion Pain and Beckons a Definitive Study.

Ann Emerg Med 2018 Jun 9;71(6):779-782. Epub 2018 Mar 9.

University of Arizona College of Medicine, Tucson, AZ. Electronic address:

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http://dx.doi.org/10.1016/j.annemergmed.2018.01.036DOI Listing
June 2018
2 Reads

ACUTE RETINAL NECROSIS AND CONTRALATERAL CUTANEOUS ERUPTION AFTER THE SHINGLES VACCINE.

Retin Cases Brief Rep 2018 Mar 8. Epub 2018 Mar 8.

Department of Ophthalmology, New York Medical College.

Purpose: To the best of our knowledge, we present a rare case report describing an occurrence of acute retinal necrosis in an otherwise healthy individual who received the shingles vaccine.

Methods: Observational case report.

Patient: A 63-year-old healthy and immunocompetent white man presented with change of vision in the left eye after blunt trauma. Read More

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http://dx.doi.org/10.1097/ICB.0000000000000729DOI Listing
March 2018
2 Reads

First report of Acanthamoeba genotype T8 human keratitis.

Acta Microbiol Immunol Hung 2018 Mar 23;65(1):73-79. Epub 2018 Feb 23.

2 Department of Ophthalmology, Semmelweis University , Budapest, Hungary.

Acanthamoeba has a worldwide distribution in the environment and it is capable of causing a painful sight-threatening disease of the cornea designated as Acanthamoeba keratitis (AK). Nowadays, the cases of AK have surged all over the world along with its disease burden due to increasing use of contact lenses used not only for optical correction but also for cosmetic purposes. In our present work, epithelial abrasion of a 27-year-old female soft contact lens wearer with keratitis was examined. Read More

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http://dx.doi.org/10.1556/030.65.2018.007DOI Listing
March 2018
13 Reads

Airborne particulate matter impairs corneal epithelial cells migration via disturbing FAK/RhoA signaling pathway and cytoskeleton organization.

Nanotoxicology 2018 05 20;12(4):312-324. Epub 2018 Feb 20.

c Department of Public Health And Preventive Medicine, School of Medicine , Jinan University , Guangzhou , China.

Background: Cornea is the outmost structure of the eye and exposed directly to the air pollution. However, little is known about the effect of PM2.5 on corneal epithelium, which is critical for maintenance of cornea homeostasis and visual function. Read More

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http://dx.doi.org/10.1080/17435390.2018.1440651DOI Listing
May 2018
12 Reads
6.410 Impact Factor

Epothilone B Speeds Corneal Nerve Regrowth and Functional Recovery through Microtubule Stabilization and Increased Nerve Beading.

Sci Rep 2018 Feb 8;8(1):2647. Epub 2018 Feb 8.

International Ocular Surface Research Center, Institute of Ophthalmology, Key Laboratory for Regenerative Medicine of the Ministry of Education, Jinan University, Guangzhou, China.

The successful restoration of corneal innervation and function after a corneal injury is a clinically challenging issue. Structural and functional recovery after a nerve injury involves a complex series of steps in which microtubules play a key role. The aim of the current study was to investigate the effects of epothilone B (EpoB), a microtubule-stabilizing agent, on corneal innervation and the functional recovery of the corneal nerve in mice after corneal epithelial abrasion. Read More

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http://dx.doi.org/10.1038/s41598-018-20734-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805685PMC
February 2018
10 Reads

Corneal abrasion and microbial contamination in horses following general anaesthesia for non-ocular surgery.

Vet Anaesth Analg 2018 May 9;45(3):278-284. Epub 2018 Jan 9.

Phillip Leverhulme Equine Hospital, Institute of Veterinary Science, University of Liverpool, Liverpool, UK; Institute of Aging and Chronic Disease, University of Liverpool, Liverpool, UK.

Objective: To evaluate the incidence of corneal abrasions/ulceration and microbial contamination in horses undergoing general anaesthesia.

Study Design: Prospective, observational, clinical study.

Animals: A total of 40 client-owned healthy horses scheduled for elective non-ophthalmic procedures. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S14672987183000
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http://dx.doi.org/10.1016/j.vaa.2017.12.002DOI Listing
May 2018
19 Reads

Corneal abrasion following anaesthesia for non-ocular surgical procedures: A case-controlled study.

J Perioper Pract 2017 Nov;27(11):247-253

Division of Ophthalmology, NYU Winthrop Hospital, Mineola, NY 11501, USA and Department of Ophthalmology, The New York Eye and Ear Infirmary of Mount Sinai, New York, NY 10003, USA.

The aim of this study was to identify risk factors associated with perioperative corneal abrasion at a single hospital in Mineola, New York (United States). A chart review was conducted of patients with perioperative corneal abrasion following non-ocular surgery and age-matched controls between June 2011 and November 2013. An age-stratified logistic regression model evaluated the association between corneal abrasion and potentially predisposing variables. Read More

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http://journals.sagepub.com/doi/10.1177/175045891702701102
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http://dx.doi.org/10.1177/175045891702701102DOI Listing
November 2017
3 Reads

Pediatric Sports- and Recreation-Related Eye Injuries Treated in US Emergency Departments.

Pediatrics 2018 02 8;141(2). Epub 2018 Jan 8.

Center for Injury Research and Policy, Nationwide Children's Hospital, Columbus, Ohio;

Objectives: To investigate the epidemiologic characteristics of sports- and recreation-related eye injuries among children in the United States.

Methods: Data from the National Electronic Injury Surveillance System were analyzed in a retrospective study of children ≤17 years of age treated in US emergency departments for sports- and recreation-related eye injuries from 1990 to 2012.

Results: From 1990 through 2012, an estimated 441 800 (95% confidence interval: 378 868-504 733) children were treated in US emergency departments for sports- and recreation-related eye injuries, averaging 26. Read More

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http://dx.doi.org/10.1542/peds.2017-3083DOI Listing
February 2018
2 Reads

Intraoperative changes in corneal structure during excimer laser phototherapeutic keratectomy (PTK) assessed by intraoperative optical coherence tomography.

Graefes Arch Clin Exp Ophthalmol 2018 Mar 4;256(3):575-581. Epub 2018 Jan 4.

Department of Ophthalmology, University of Cologne, Kerpener Strasse 62, 50924, Cologne, Germany.

Purpose: Excimer laser phototherapeutic keratectomy (PTK) is a safe treatment for superficial corneal opacities, e.g., in corneal dystrophies or degenerations. Read More

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http://dx.doi.org/10.1007/s00417-017-3867-7DOI Listing
March 2018
49 Reads

Traumatic eye ball luxation: A stepwise approach to globe salvage.

Saudi J Ophthalmol 2017 Oct-Dec;31(4):260-265. Epub 2017 Jun 13.

Department of Ophthalmology, MGM Medical College and University, Kamothe, Navi Mumbai, Maharashtra, India.

Craniofacial trauma is often associated with orbital and ocular injuries. We report a case of a 21-year-old male with motor vehicular accident, orbital roof blow-in fracture, cerebrospinal fluid (CSF) leak, and left sided globe luxation with corneal abrasion and complete conjunctival denuding. The patient was managed by a multispeciality team and the eyeball was protected by amniotic membrane graft (AMG) biological dressing with novel use of inverted sterile metallic bowl as mechanical protection till the patient stabilized. Read More

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http://dx.doi.org/10.1016/j.sjopt.2017.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717501PMC
June 2017
8 Reads

Patterns of ophthalmic emergencies presenting to a referral hospital in Medina City, Saudi Arabia.

Saudi J Ophthalmol 2017 Oct-Dec;31(4):243-246. Epub 2016 Apr 1.

Department of Ophthalmology, Taibah University, Medina, Saudi Arabia.

Background: Data are required on ophthalmic cases that present to the emergency eye clinics in Madinah, Saudi Arabia for proper allocation of healthcare resources.

Objectives: To determine the frequency and various diagnoses of patients presenting to the A&E at Ohud Hospital, Madinah, Saudi Arabia.

Methods: Data was collected prospectively for all patients who presented to the A&E ophthalmology clinic from June 2014 to September 2014. Read More

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http://dx.doi.org/10.1016/j.sjopt.2016.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717507PMC
April 2016
3 Reads

Practice patterns in the interdisciplinary management of corneal abrasions.

Can J Ophthalmol 2017 Dec 10;52(6):548-551. Epub 2017 May 10.

Department of Ophthalmology, McGill University Health Center, McGill University, Montreal, Que.

Objective: To characterize the treatment and follow-up patterns of corneal abrasions at an academic health centre.

Methods: This is a retrospective review of 90 cases of corneal abrasions over a 2-year period at a tertiary care academic hospital, of which 75 were seen by the ophthalmology department. All consultations primarily for corneal abrasion, as determined by the emergency department physician, were included in the study. Read More

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http://dx.doi.org/10.1016/j.jcjo.2017.03.016DOI Listing
December 2017
5 Reads

A reversible thermoresponsive sealant for temporary closure of ocular trauma.

Sci Transl Med 2017 Dec;9(419)

The Mork Family Department of Chemical Engineering and Materials Science, University of Southern California, Los Angeles, CA 90089, USA.

Open globe injuries are full-thickness injuries sustained to the eye wall (cornea or sclera), which cause immediate drops in intraocular pressure that may lead to retinal detachment and permanent vision loss if not treated rapidly after injury. The current standard of care for open globe injuries consists of suturing the margins closed, but the technique can be time-consuming, requires specialized training and equipment, and can lead to patient discomfort, abrasion, and infection from eye rubbing. We engineered an injectable, thermoresponsive sealant (TRS) and a custom tool to occlude open globe injuries. Read More

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http://stm.sciencemag.org/lookup/doi/10.1126/scitranslmed.aa
Publisher Site
http://dx.doi.org/10.1126/scitranslmed.aan3879DOI Listing
December 2017
39 Reads

Exposures to automatic dishwashing rinse aids reported to the United Kingdom National Poisons Information Service 2008-2016.

Clin Toxicol (Phila) 2018 Jun 20;56(6):427-432. Epub 2017 Nov 20.

a NPIS (Birmingham Unit) , City Hospital , Birmingham , UK.

Objective: To determine the toxicity of rinse aids which are used as drying aids to remove water from crockery.

Methods: Enquiries to the UK National Poisons Information Service (NPIS) were analysed retrospectively for the period January 2008 to December 2016.

Results: There were 855 enquiries relating to 828 patients; children aged 5 years or less accounted for 91. Read More

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http://dx.doi.org/10.1080/15563650.2017.1393083DOI Listing
June 2018
5 Reads

Eyelid syringocystadenoma papilliferum: A novel presentation with major review.

Orbit 2018 Jun 20;37(3):171-174. Epub 2017 Oct 20.

a Department of Ophthalmology and Visual Sciences , Montefiore Medical Center, Albert Einstein College of Medicine , Bronx , NY , USA.

A major review of the literature of syringocystadenoma papilliferum's (SCAP's) presentation and management is presented. In addition, a case report of this unique diagnosis presenting as a corneal abrasion in a 66-year-old-male is included. This benign adnexal tumor of the apocrine glands is most commonly found in the face and neck. Read More

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http://dx.doi.org/10.1080/01676830.2017.1383477DOI Listing
June 2018
10 Reads

[Superglue instead of eye ointment; the sealed eye: often frightening and painful, generally ends well].

Authors:
R H C Zegers

Ned Tijdschr Geneeskd 2017 ;161:D1742

Diakonessenhuis, afd. Oogheelkunde, Utrecht/Zeist/Doorn.

Background: Not infrequently, patients mistakenly put glue in their eye. This often induces considerable emotional and physical reaction.

Case Description: A 20-year-old man came to the Emergency Department at night because he had mistaken a tube of superglue for his eye ointment and instilled the glue into his right eye. Read More

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June 2018
1 Read

Medicated ocular bandages and corneal health: potential excipients and active pharmaceutical ingredients.

Pharm Dev Technol 2018 Mar 21;23(3):255-260. Epub 2017 Sep 21.

a Drug Delivery Research Group, School of Science , Auckland University of Technology , Auckland , New Zealand.

Corneal blindness can occur due to improper healing of the corneal tissues after induced injury or abrasion which can be accidental, pathogenic, or after corneal surgery. Abnormal regulation of the healing mechanisms can lead to corneal opacity. Reducing inflammation and promoting epithelial wound healing are crucial for scar-free corneal recovery without eyesight complications. Read More

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https://www.tandfonline.com/doi/full/10.1080/10837450.2017.1
Publisher Site
http://dx.doi.org/10.1080/10837450.2017.1377232DOI Listing
March 2018
16 Reads