6,851 results match your criteria Cornea[Journal]


Deep Anterior Lamellar Keratoplasty in Eyes With Intrastromal Corneal Ring Segments.

Cornea 2019 Feb 12. Epub 2019 Feb 12.

Department of Ophthalmology, Ospedali Privati Forlì, Forlì, Italy.

Purpose: To evaluate the possibility of using the intrastromal corneal ring segments (ICRSs) previously implanted as a depth reference for performing pneumatic dissection in deep anterior lamellar keratoplasty (DALK).

Methods: The depth of placement of 2 symmetrical ICRSs placed in the superior and inferior midperipheral cornea of 4 eyes of 4 patients with keratoconus was measured by means of anterior segment optical coherence tomography. Because of irregular and/or high astigmatism, DALK using pneumatic dissection was performed in all eyes. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001906DOI Listing
February 2019

Double-Line Reflection Pattern as a Simple Method to Determine Graft Orientation of Descemet Membrane Endothelial Keratoplasty.

Cornea 2019 Feb 7. Epub 2019 Feb 7.

Centro Oftalmológico Virgilio Galvis, Floridablanca, Colombia.

Purpose: To describe a simple finding, consisting of a double-line reflection from the graft inside the anterior chamber, that can be used to determine the correct donor tissue orientation in Descemet membrane endothelial keratoplasty: which we would like to call Berrospi's sign.

Methods: Evaluation of the presence of linear reflection from the donor tissue when implanted in the anterior chamber.

Results: A distinctive double-line reflection pattern was identified when careful observation of the curls of the scroll was performed under the surgical microscope, which was a confirmatory sign that the graft was in the correct position. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001889DOI Listing
February 2019

Donor-Related Nontuberculous Mycobacterial Interface Infection After Descemet Membrane Endothelial Keratoplasty.

Cornea 2019 Feb 7. Epub 2019 Feb 7.

Department of Ophthalmology, University Hospitals Leuven, Leuven, Belgium.

Purpose: To describe the first reported case of Mycobacterium chelonae-related interface keratitis after Descemet membrane endothelial keratoplasty (DMEK), successfully treated with DMEK exchange.

Methods: A case of donor-related DMEK interface keratitis, treated with medical therapy and DMEK exchange, was studied retrospectively.

Results: A patient with Fuchs endothelial dystrophy developed infectious interface keratitis after DMEK. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001895DOI Listing
February 2019

Micropulse Transscleral Cyclophotocoagulation in Keratoplasty Eyes.

Cornea 2019 Feb 6. Epub 2019 Feb 6.

Price Vision Group, Indianapolis, IN.

Purpose: To assess the outcomes of micropulse transscleral cyclophotocoagulation for intraocular pressure (IOP) control in keratoplasty eyes.

Methods: Outcomes of micropulse laser treatments of postkeratoplasty eyes were retrospectively reviewed. IOP was assessed with applanation tonometry. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001897DOI Listing
February 2019

Reply.

Cornea 2019 Feb 5. Epub 2019 Feb 5.

Department of Ophthalmology, UPMC Eye Center, University of Pittsburgh School of Medicine, Pittsburgh, PA.

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http://dx.doi.org/10.1097/ICO.0000000000001894DOI Listing
February 2019

Vision-Related Quality of Life in Keratoconus: A Save Sight Keratoconus Registry Study.

Cornea 2019 Feb 5. Epub 2019 Feb 5.

Save Sight Institute, University of Sydney, Sydney, Australia.

Purpose: To assess vision-related quality of life using the Impact of Vision Impairment Questionnaire (IVI) in patients with keratoconus enrolled in the Save Sight Keratoconus Registry.

Methods: In this cross-sectional study, data on 107 keratoconic patients were collected through a prospectively designed web-based registry from a quaternary referral eye hospital and 2 corneal subspecialty practices. Vision-related quality of life was evaluated using the IVI. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001899DOI Listing
February 2019

Comparison of Corneal Epithelial Remodeling Over 2 Years in LASIK Versus SMILE: A Contralateral Eye Study.

Cornea 2019 Mar;38(3):290-296

Laservision.gr Clinical and Research Eye Institute, Athens, Greece.

Purpose: To evaluate 3-dimensional epithelial remodeling in patients undergoing myopic laser in situ keratomileusis (LASIK) versus small incision lenticule extraction (SMILE).

Methods: In a prospective randomized contralateral eye study of LASIK versus SMILE procedures, 21 consecutive patients (42 eyes) were evaluated with corneal epithelial mapping by anterior segment optical coherence tomography for up to 2 years.

Results: In the LASIK group, central epithelial thickness increased from 52. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001821DOI Listing
March 2019
2 Reads

Use of Topical Rho Kinase Inhibitors in the Treatment of Fuchs Dystrophy After Descemet Stripping Only.

Cornea 2019 Feb 1. Epub 2019 Feb 1.

Division of Ophthalmology, NorthShore University HealthSystem, Glenview, IL.

Purpose: Fuchs corneal dystrophy (FD) is a common cause of endothelial keratoplasty. Recently, a series of FD cases treated with Descemet stripping only (DSO) demonstrated recovery of the central endothelium without transplantation of donor cells. Ripasudil, a rho kinase inhibitor, has been shown to promote corneal endothelial wound healing in animal models. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001883DOI Listing
February 2019
3 Reads

Long-term Chronological Changes in Very Asymmetric Keratoconus.

Cornea 2019 Jan 29. Epub 2019 Jan 29.

Department of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan.

Purpose: To investigate chronological changes in patients with very asymmetric keratoconus (KC) by Scheimpflug-based corneal tomographic evaluation.

Methods: We retrospectively reviewed the clinical records of 382 patients with KC attending a university hospital. Patients who were diagnosed with KC in one eye and forme fruste keratoconus in the other eye at the last visit and followed up with Scheimpflug-based tomographic corneal imaging were included. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001890DOI Listing
January 2019

Aspiration of Tri-folded, Endothelium-In Grafts for Descemet Membrane Endothelial Keratoplasty.

Cornea 2019 Jan 29. Epub 2019 Jan 29.

Wilmer Eye Institute at Johns Hopkins, Baltimore, MD.

Purpose: In Descemet membrane endothelial keratoplasty (DMEK), loading and positioning of tri-folded grafts into a cartridge is generally conducted with forceps or a hook, risking graft tear or trauma. We demonstrate the feasibility of loading tri-folded grafts into a cartridge with no touch to the endothelium required beyond the tri-folding process.

Methods: A corneoscleral rim with a prestripped DMEK graft is placed into a petri dish. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001888DOI Listing
January 2019
1 Read

Efficacy of Omega-3 Fatty Acid Supplementation for Treatment of Dry Eye Disease: A Meta-Analysis of Randomized Clinical Trials.

Cornea 2019 Jan 29. Epub 2019 Jan 29.

Ophthalmolgy Unit, S.Orsola-Malpighi University Hospital, University of Bologna, Bologna, Italy.

Purpose: To assess whether omega-3 fatty acid (FA) supplementation is more efficacious than placebo in amelioration of signs and symptoms of dry eye disease.

Methods: We performed a systematic literature search in PubMed, Scopus, Web of Science, and Cochrane Central Register of Controlled Trials databases. We included randomized clinical trials comparing omega-3 FA supplementation with placebo in patients with dry eye disease. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001884DOI Listing
January 2019

Polyquaternium-1-Associated Dendritiform Keratopathy.

Cornea 2019 Jan 29. Epub 2019 Jan 29.

Department of Ophthalmology, Baylor College of Medicine, Houston, TX.

Purpose: To report a case of polyquaternium-1 (Polyquad, PQ-1)-associated dendritiform keratopathy that developed after exposure to the tear substitute Systane (Alcon Laboratories, Inc, Fort Worth, TX).

Methods: A retrospective review of the case was performed.

Results: Dendritiform keratopathy developed in the patient after an increase in the use of topical Systane from 4 times per day to every hour. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001885DOI Listing
January 2019

Effectiveness of Cryopreserved Amniotic Membrane Transplantation in Corneal Ulceration: A Meta-Analysis.

Cornea 2019 Jan 29. Epub 2019 Jan 29.

Clinical College of Ophthalmology, Tianjin Medical University, Tianjin, China.

Purpose: To evaluate the effectiveness of cryopreserved amniotic membrane transplantation (AMT) in corneal ulceration.

Methods: The following electronic databases were searched: PubMed, EMBASE, and Cochrane Library. We evaluated the corneal epithelium healing rate (CEHR) and vision improvement rate (VIR) after AMT in the treatment of corneal ulceration. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001866DOI Listing
January 2019

Intraoperative Optical Coherence Tomography to Guide Corneal Biopsy: A Case Report.

Cornea 2019 Jan 25. Epub 2019 Jan 25.

Department of Ophthalmology, Casey Eye Institute, Oregon Health & Science University, Portland, OR.

Purpose: To report on a new application of intraoperative optical coherence tomography (OCT) as a real-time imaging tool to help guide corneal biopsy.

Methods: Single case report. After the negative result of a corneal biopsy, we used intraoperative OCT during repeat biopsy to assist in depth and acquisition of an anterior stromal opacity suspected to be immunoglobulin deposits. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001873DOI Listing
January 2019

Sjögren's Syndrome: More Than Just Dry Eye.

Cornea 2019 Jan 22. Epub 2019 Jan 22.

Department of Health Services, Policy, and Practice, Center for Evidence Synthesis in Health, Brown University School of Public Health, Providence, RI.

Purpose: Sjögren's syndrome (SS) is a common autoimmune disease affecting about four million Americans. Although approximately 1 in 10 patients with clinically-significant aqueous deficient dry eye has underlying SS, widespread underappreciation of SS leads to significant underdiagnosis, delays in diagnosis, and consequent morbidity and mortality. The purpose of this article is to illustrate that in addition to dry eye, SS can cause serious, vision-threatening extraglandular ocular manifestations. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001865DOI Listing
January 2019
3 Reads

Keratometric, Pachymetric, and Surface Elevation Characterization of Corneas With Fuchs Endothelial Corneal Dystrophy Treated With DMEK.

Cornea 2019 Jan 22. Epub 2019 Jan 22.

Cornea Unit, Department of Ophthalmology, Ramón y Cajal University Hospital. Madrid, Spain.

Purpose: To characterize pachymetric, keratometric, and surface elevation parameters in pseudophakic eyes with Fuchs dystrophy that underwent Descemet membrane endothelial keratoplasty (DMEK) and to compare these characteristics with those in normal pseudophakic eyes.

Methods: Postoperative corneal tomography with a median follow-up of 20 months was evaluated using the Pentacam tomographer on 46 DMEK eyes. Results were compared with data from an age-matched cohort of 46 normal eyes. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001875DOI Listing
January 2019
4 Reads

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Authors:
Cosimo Mazzotta

Cornea 2019 Jan 23. Epub 2019 Jan 23.

Siena Crosslinking Center.

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http://dx.doi.org/10.1097/ICO.0000000000001882DOI Listing
January 2019

Measurement of Corneal Biomechanical Properties in Diabetes Mellitus Using the Ocular Response Analyzer and the Corvis ST.

Cornea 2019 Jan 23. Epub 2019 Jan 23.

Department of Ophthalmology, University Hospital Dresden, Dresden, Germany.

Purpose: Hyperglycemia in diabetes mellitus (DM) might induce changes in corneal biomechanics. Therefore, biomechanical properties of the cornea were measured using the ocular response analyzer and the Corvis ST.

Methods: In the study, 35 eyes of 35 diabetic patients were included. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001879DOI Listing
January 2019

Reflections on the Barcelona Principles-Planning for the Future.

Cornea 2019 Jan 23. Epub 2019 Jan 23.

Netherlands Institute for Innovative Ocular Surgery, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1097/ICO.0000000000001874DOI Listing
January 2019

Surgical Corneal Anatomy in Deep Anterior Lamellar Keratoplasty: Suggestion of New Acronyms.

Cornea 2019 Jan 23. Epub 2019 Jan 23.

Clinica degli Occhi Sarnicola, Grosseto, Italy.

Deep anterior lamellar keratoplasty (DALK) is the ideal surgery for corneal stromal diseases with a healthy endothelium. This technique offers substantial advantages compared with penetrating keratoplasty, primarily the avoidance of endothelial rejection and longer graft survival. Several DALK techniques have been described and classified into 2 categories, descemetic DALK (dDALK) and predescemetic DALK (pdDALK) depending on whether Descemet membrane-endothelium was thought to be exposed or minimal residual stroma was left behind. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001845DOI Listing
January 2019
1 Read

Lucia and Beyond: Development of an Affordable Keratoprosthesis.

Cornea 2019 Jan 23. Epub 2019 Jan 23.

Department of Ophthalmology, Disruptive Technology Laboratory, Massachusetts Eye & Ear, Harvard Medical School, Boston, MA.

Purpose: Severe corneal disease contributes significantly to the global burden of blindness. Corneal allograft surgery remains the most commonly used treatment, but does not succeed long term in every patient, and the odds of success fall with each repeated graft. The Boston keratoprosthesis type I has emerged as an alternative to repeat corneal allograft. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001880DOI Listing
January 2019
1 Read

Impact of Nanostructured Lipid Carriers as an Artificial Tear Film in a Rabbit Evaporative Dry Eye Model.

Cornea 2019 Jan 23. Epub 2019 Jan 23.

Department of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, Thailand.

Purpose: To characterize formulations of nanostructured lipid carriers (NLCs) as an artificial tear film and evaluate their efficacy in protecting the ocular surface epithelial cells from desiccating stress in vivo.

Methods: The physicochemical properties of NLCs, produced with components similar to the tear film such as phosphatidylcholine and squalene, were determined. In vitro cytotoxicity of NLCs was evaluated by a short-time exposure test in porcine corneal epithelial cells using a methyl thiazol diphenyl-tetrazolium bromide assay. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001867DOI Listing
January 2019
1 Read

Comparative Functional Outcomes After Corneal Crosslinking Using Standard, Accelerated, and Accelerated With Higher Total Fluence Protocols.

Cornea 2019 Jan 23. Epub 2019 Jan 23.

Keck School of Medicine of USC, Los Angeles, CA.

Purpose: To compare the relative 12-month corneal crosslinking (CXL) functional outcomes using standard protocol and accelerated protocols in patients with progressive keratoconus.

Methods: CXL was performed using 3 epithelium-off protocols: standard [3 mW/cm for 30 minutes, 5.4 J/cm (S3/30-CXL)], accelerated with equivalent total irradiance [9 mW/cm for 10 minutes, 5. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001878DOI Listing
January 2019
1 Read
2.360 Impact Factor

Do Donated Corneas Become Transplanted Corneas? The Causes of Discard in Southern Brazil.

Cornea 2019 Jan 23. Epub 2019 Jan 23.

Health Sciences Department, State University of Paraná, Paranavaí, Paraná, Brazil.

Purpose: To analyze the number of discarded donated corneas and the causes associated with discard in southern Brazil.

Methods: This retrospective, cross-sectional, and analytic study of donor corneal discards and their associated factors and geospatial distribution was based on a macroregional strategy conducted from 2011 to 2015 in Paraná, southern Brazil. The dataset included all cornea donations from patients who died of cardiac arrest at ages between 3 and 70 years. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001856DOI Listing
January 2019

Biobanking of Dehydrated Human Donor Corneal Stroma to Increase the Supply of Anterior Lamellar Grafts.

Cornea 2019 Jan 23. Epub 2019 Jan 23.

International Center for Ocular Physiopathology, The Veneto Eye Bank Foundation, Venice, Italy.

Purpose: To investigate the effect of dehydration on human donor corneal stroma for biobanking.

Methods: Epithelium and endothelium of research-grade human donor corneas (n = 12) were scraped off, leaving a bare stroma with attached sclera. The tissues were placed in a large Petri dish prefilled with silica gel in the periphery and stored at room temperature for 14 days. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001876DOI Listing
January 2019
1 Read

Reply.

Cornea 2019 Jan 21. Epub 2019 Jan 21.

Eye Center, University Hospital Freiburg, Freiburg im Breisgau, Germany.

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http://dx.doi.org/10.1097/ICO.0000000000001869DOI Listing
January 2019
3 Reads

Novel Unassisted Pterygium Excision Technique.

Cornea 2019 Jan 21. Epub 2019 Jan 21.

Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1097/ICO.0000000000001853DOI Listing
January 2019
4 Reads

Comment on: "Influence of Postoperative Intraocular Pressure on Graft Detachment After Descemet Membrane Endothelial Keratoplasty".

Cornea 2019 Jan 21. Epub 2019 Jan 21.

Tej Kohli Cornea Institute, LV Prasad Eye Institute, Hyderabad, India.

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http://dx.doi.org/10.1097/ICO.0000000000001868DOI Listing
January 2019
6 Reads

Influence of Lens Status on Outcomes of Descemet Membrane Endothelial Keratoplasty.

Cornea 2019 Jan 21. Epub 2019 Jan 21.

Division of Cornea and Refractive Surgery, Department of Ophthalmology, Duke University Eye Center, Durham, NC.

Purpose: To evaluate whether lens status influences clinical outcomes of Descemet membrane endothelial keratoplasty (DMEK) in patients who underwent DMEK in phakia, pseudophakia, or combined with cataract surgery (triple).

Methods: A retrospective review of 139 eyes (107 patients) with symptomatic Fuchs' dystrophy or secondary corneal edema was performed. Patients were divided into 3 groups: 1) DMEK + cataract surgery, 2) DMEK in pseudophakia, and 3) DMEK in phakia. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001872DOI Listing
January 2019
7 Reads

Comparison of Donor Cornea Endothelial Cell Density Determined by Eye Banks and by a Central Reading Center in the Cornea Preservation Time Study.

Cornea 2019 Jan 16. Epub 2019 Jan 16.

Department of Ophthalmology and Visual Sciences, Case Western Reserve University, University Hospitals Eye Institute, Cleveland, OH.

Purpose: To evaluate agreement between eye banks (EBs) and a reading center on endothelial cell density (ECD) determinations in the Cornea Preservation Time Study.

Methods: The Cornea Image Analysis Reading Center (CIARC) performed variable frame image analysis on EB-obtained-preoperative central endothelial images (after lamellar dissection for Descemet stripping automated endothelial keratoplasty by the EBs or before shipping, if surgeon prepared) to determine ECD. The EBs performed their usual method of ECD determination. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001846DOI Listing
January 2019
1 Read

Feasibility of Intraocular Projection for Treatment of Intractable Corneal Opacity.

Cornea 2019 Jan 16. Epub 2019 Jan 16.

Department of Ophthalmology and Visual Sciences, The University of Illinois Chicago, Chicago, IL.

Despite many decades of research and development, corneal opacity remains a leading cause of reversible blindness worldwide. Corneal transplantation and keratoprosthesis can restore corneal clarity, but both have well-known limitations. High-resolution electronic microdisplays may offer an alternative to traditional methods of treating corneal disease using an intraocular implant to project imagery onto the retina, obviating the need for a clear cornea. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001852DOI Listing
January 2019
2 Reads

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Authors:
Qi Lin Zhiqiang Pan

Cornea 2019 Jan 10. Epub 2019 Jan 10.

Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Science Key Laboratory, Beijing, China.

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http://dx.doi.org/10.1097/ICO.0000000000001859DOI Listing
January 2019
1 Read

Comparison of Graft Thickness Measured by an Eye Bank With Graft Thickness Measured After Descemet Stripping Automated Endothelial Keratoplasty.

Cornea 2019 Jan 9. Epub 2019 Jan 9.

Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Purpose: To compare donor lenticule thickness reported by the eye bank with lenticule thickness measured at 6 months after Descemet stripping automated endothelial keratoplasty (DSAEK).

Methods: This prospective, interventional case series enrolled 30 eyes from 30 patients who underwent DSAEK using precut eye bank tissue. Preoperative thickness measurements of the donor lenticules were taken centrally and at pericentral and peripheral graft areas using an anterior segment optical coherence tomography system. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001855DOI Listing
January 2019
2 Reads

Epi-Bowman Blunt Keratectomy Versus Diluted EtOH Epithelial Removal in Myopic Photorefractive Keratectomy: A Prospective Contralateral Eye Study.

Cornea 2019 Jan 9. Epub 2019 Jan 9.

LaserVision Clinical and Research Eye Institute, Athens, Greece.

Purpose: To compare the outcomes and complications of Epi-Bowman blunt keratectomy (EBK) using a blunt epikeratome (Epi-Clear, Orca Surgical, Israel), with alcohol delamination of the corneal epithelium during photorefractive keratectomy (PRK) in contralateral eyes.

Methods: This prospective, randomized contralateral eye study included 44 eyes of 22 patients undergoing PRK for bilateral myopia or myopic astigmatism. In each patient, epithelial delimitation was performed using an Epi-Clear epikeratome EBK (EBK group) on 1 eye and diluted ethanol (EtOH) on the fellow eye (EtOH group). Read More

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http://dx.doi.org/10.1097/ICO.0000000000001863DOI Listing
January 2019
4 Reads

Reduction of Acanthamoeba Cyst Density Associated With Treatment Detected by In Vivo Confocal Microscopy in Acanthamoeba Keratitis.

Cornea 2019 Jan 9. Epub 2019 Jan 9.

Department of Ophthalmology, UCLA, Los Angeles, CA.

Purpose: Acanthamoeba keratitis (AK) is a severe vision-threatening ocular infection that is frequently a diagnostic challenge. Treatment course is lengthy and often not fully effective. Contact lens wear has been recognized as the prime risk factor for AK. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001857DOI Listing
January 2019
2 Reads

Retinoscopy as a Screening Tool for Keratoconus.

Cornea 2019 Jan 9. Epub 2019 Jan 9.

Department of Ophthalmology, Al-Nahdha Hospital, Muscat, Oman.

Purpose: To investigate the validity and reliability of retinoscopy in screening for keratoconus using the rotating Pentacam Scheimpflug camera as the gold standard comparison.

Methods: Patients between the ages of 10 and 30 years who were referred to the outpatient clinic with keratoconus, keratoconus suspect, reduced vision, eye discomfort or frequent change of glasses, or for refraction or refractive surgery, were screened by two independent and masked retinoscopists for the presence of scissoring reflex. Patients then underwent vision testing, slit lamp examination, and Pentacam imaging. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001843DOI Listing
January 2019
1 Read

Secondary Intraocular Lens Implantation After Simultaneous Penetrating Keratoplasty and Cataract Extraction for Coexisting Corneal and Lens Opacities.

Cornea 2019 Jan 9. Epub 2019 Jan 9.

Ophthalmology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.

Purpose: To report the results of a new approach to the 2-stage surgical management of coexisting visually significant corneal opacities and cataract.

Methods: A retrospective analysis of eyes with corneal opacities and cataract that were surgically treated with simultaneous penetrating keratoplasty and cataract surgery, followed by secondary intraocular lens (IOL) implantation after removal of corneal sutures, was conducted. The parameters used for assessment were the following: mean percentage of graft endothelial cell loss after IOL implantation, deviation of the postoperative mean spherical equivalent from the target refraction, and mean uncorrected distance visual acuity (UDVA). Read More

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http://dx.doi.org/10.1097/ICO.0000000000001861DOI Listing
January 2019
1 Read

Scleral Ischemia in Acute Ocular Chemical Injury: Long-Term Impact on Rehabilitation With Limbal Stem Cell Therapy.

Cornea 2019 Feb;38(2):198-202

Dr. Shroff's Charity Eye Hospital, Daryaganj, New Delhi, India.

Purpose: This study describes the impact of scleral ischemia on globe survival in cases of acute chemical injury and the outcome of limbal stem cell transplant in these eyes.

Methods: This is a single-center, retrospective case study that reviews outcomes in all patients with acute chemical injury of grades IV and above who presented within 6 weeks from injury. The period of the study is between May 2012 and May 2017. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001807DOI Listing
February 2019
1 Read

A Multicenter Study Evaluating the Risk Factors and Outcomes of Repeat Descemet Stripping Endothelial Keratoplasty.

Cornea 2019 Feb;38(2):177-182

Department of Ophthalmology, Loyola University Medical Center, Maywood, IL.

Purpose: Descemet stripping endothelial keratoplasty (DSEK), currently the most common procedure for managing corneal endothelial dysfunction, may be repeated following DSEK failure from a variety of causes. This multicenter study reports the risk factors and outcomes of repeat DSEK.

Methods: This was an institutional review board-approved multicenter retrospective chart review of patients who underwent repeat DSEK. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001817DOI Listing
February 2019
6 Reads

Comment on "Visual Outcomes and Prognostic Factors of Successful Penetrating Keratoplasty in 0- to 7-Year-Old Children With Congenital Corneal Opacities".

Cornea 2018 Dec 31. Epub 2018 Dec 31.

Department Cornea & Anterior Segment Services, CL Gupta Eye Institute, Moradabad, Uttar Pradesh, India.

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http://dx.doi.org/10.1097/ICO.0000000000001860DOI Listing
December 2018
2 Reads

Comment on "Visual Outcomes and Prognostic Factors of Successful Penetrating Keratoplasty in 0- to 7-Year-Old Children With Congenital Corneal Opacities".

Cornea 2018 Dec 31. Epub 2018 Dec 31.

Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

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http://dx.doi.org/10.1097/ICO.0000000000001862DOI Listing
December 2018
1 Read

Intraoperative Optical Coherence Tomography-Guided Femtosecond Laser-Assisted Deep Anterior Lamellar Keratoplasty.

Cornea 2018 Dec 31. Epub 2018 Dec 31.

The Institute for Refractive and Ophthalmic Surgery, (IROC), Zurich, Switzerland.

Purpose: To describe the feasibility and outcomes of intraoperative optical coherence tomography (OCT)-guided, femtosecond laser-assisted deep anterior lamellar keratoplasty in which the lamellar and tunnel cuts were completed by laser.

Methods: The Ziemer Z8 system was used to scan the corneas intraoperatively and guide the stromal lamellar and tunnel cuts created by the laser. Thirty porcine eyes and 3 human cadaver globes were used to evaluate the accuracy of laser-created intrastromal tunnels and the feasibility of achieving big-bubble pneumatic dissection. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001851DOI Listing
December 2018
6 Reads

Novel Use of Telemedicine for Corneal Tissue Evaluation in Eye Banking: Establishing a Standardized Approach for the Remote Evaluation of Donor Corneas for Transplantation.

Cornea 2018 Dec 31. Epub 2018 Dec 31.

Department of Ophthalmology, Weill Cornell Medical College, New York, NY.

Purpose: To determine the feasibility of using telemedicine consultations in the evaluation of recovered donor corneas for transplant suitability.

Methods: This study aims to establish and test the minimum imaging requirements for telemedical consultations of corneal tissue by remote eye bank medical directors. Digital images from the slit lamp, optical coherence tomography, and/or specular microscope were assembled into telemedical consults and emailed to 4 eye bank medical directors (M. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001848DOI Listing
December 2018
3 Reads

Cytomegalovirus Corneal Endotheliitis After Descemet Membrane Endothelial Keratoplasty.

Cornea 2018 Dec 31. Epub 2018 Dec 31.

Corneal and External Eye Disease Department, Singapore National Eye Centre, Singapore.

Purpose: To describe 4 cases of cytomegalovirus (CMV) corneal endotheliitis occurring after Descemet membrane endothelial keratoplasty (DMEK).

Methods: This is a retrospective, interventional case series. Case records of 4 patients (one eye each) diagnosed with CMV corneal endotheliitis after DMEK were reviewed retrospectively. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001847DOI Listing
December 2018
9 Reads

Global Consensus on Definition, Classification, Diagnosis, and Staging of Limbal Stem Cell Deficiency.

Cornea 2019 Mar;38(3):364-375

Department of Ophthalmology, University Hospital Erlangen and Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.

Purpose: Despite extensive knowledge gained over the last 3 decades regarding limbal stem cell deficiency (LSCD), the disease is not clearly defined, and there is lack of agreement on the diagnostic criteria, staging, and classification system among treating physicians and research scientists working on this field. There is therefore an unmet need to obtain global consensus on the definition, classification, diagnosis, and staging of LSCD.

Methods: A Limbal Stem Cell Working Group was first established by The Cornea Society in 2012. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001820DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363877PMC
March 2019
1 Read

Corneal Endothelial Cell Density and Morphology After Phacoemulsification in Patients With Primary Open-Angle Glaucoma and Cataracts: 2-Year Results of a Randomized Multicenter Trial.

Cornea 2019 Mar;38(3):325-331

University of California San Francisco, San Francisco, CA.

Purpose: To evaluate corneal endothelial cell density (ECD) and morphology 2 years after phacoemulsification in subjects from the COMPASS trial (ClinicalTrials.gov, NCT01085357) who had mild-to-moderate primary open-angle glaucoma and visually significant cataracts.

Methods: The central corneal endothelium was evaluated by serial specular microscopy at 0 to 24 months. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001826DOI Listing
March 2019
9 Reads

Association Between Sleep Quality, Mood Status, and Ocular Surface Characteristics in Patients With Dry Eye Disease.

Cornea 2019 Mar;38(3):311-317

Department of Ophthalmology, The Eye and ENT Hospital of Fudan University, Shanghai, China.

Purpose: To evaluate sleep and mood status in patients with dry eye disease (DED) and analyze the association between sleep quality, mood status, and ocular surface characteristics.

Methods: Consecutive patients with DED (N = 106) and age- and sex-matched healthy controls (N = 50) were enrolled. Tear fluid break up time (TBUT), corneal fluorescein staining, and Schirmer I tests were performed in the order listed here to evaluate dry eye. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001854DOI Listing
March 2019
2 Reads

Partial Scleral Rupture Presenting 4 Years After Laser in Situ Keratomileusis.

Cornea 2018 Dec 28. Epub 2018 Dec 28.

Department of Ophthalmology, Northwestern University Feinberg School of Medicine, Chicago, IL.

Purpose: To report a case of partial scleral rupture after laser in situ keratomileusis (LASIK) surgery.

Methods: This is a retrospective case report describing a late complication of LASIK surgery.

Results: A 32-year-old white woman with a history of LASIK surgery performed with a mechanical microkeratome 4 years previously presented for evaluation of partial bilateral scleral ruptures. Read More

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http://dx.doi.org/10.1097/ICO.0000000000001850DOI Listing
December 2018
2 Reads