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    592 results match your criteria Cooling Techniques for Hyperthermia

    1 OF 12

    Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management.
    J Vis Exp 2017 Nov 21(129). Epub 2017 Nov 21.
    Attune Medical; Department of Emergency Medicine, University of Texas, Southwestern Medical Center;
    Controlling patient temperature is important for a wide variety of clinical conditions. Cooling to normal or below normal body temperature is often performed for neuroprotection after ischemic insult (e.g. Read More

    Effects of superficial heating and insulation on walking speed in people with hereditary and spontaneous spastic paraparesis: A randomised crossover study.
    Ann Phys Rehabil Med 2017 Dec 11. Epub 2017 Dec 11.
    School of Health Professions, Faculty of Health and Human Sciences, Plymouth University, Peninsula Allied Health Centre, Derriford Road, Plymouth, PL6 8BH, United Kingdom.
    Objectives: Cooling of the lower limb in people with Hereditary and Spontaneous Spastic Paraparesis (pwHSSP) has been shown to affect walking speed and neuromuscular impairments. The investigation of practical strategies, which may help to alleviate these problems is important. The potential of superficial heat to improve walking speed has not been explored in pwHSSP. Read More

    Reduction of hyperthermia in pediatric patients with severe traumatic brain injury: a quality improvement initiative.
    J Neurosurg Pediatr 2017 Dec 1:1-7. Epub 2017 Dec 1.
    Division of Critical Care and.
    OBJECTIVE Severe traumatic brain injury remains a leading cause of morbidity and mortality in the pediatric population. Providers focus on reducing secondary brain injury by avoiding hypoxemia, avoiding hypotension, providing normoventilation, treating intracranial hypertension, and reducing cerebral metabolic demand. Hyperthermia is frequently present in patients with severe traumatic brain injury, contributes to cerebral metabolic demand, and is associated with prolonged hospital admission as well as impaired neurological outcome. Read More

    Effects of targeted temperature management on mortality and neurological outcome: A systematic review and meta-analysis.
    Eur Heart J Acute Cardiovasc Care 2017 Nov 1:2048872617744353. Epub 2017 Nov 1.
    3 Division of Cardiology, University of British Columbia, Canada.
    Aims: The purpose of this study was to conduct a systematic review, and where applicable meta-analyses, examining the evidence underpinning the use of targeted temperature management following resuscitation from cardiac arrest.

    Methods And Results: Multiple databases were searched for publications between January 2000-February 2016. Nine Population, Intervention, Comparison, Outcome questions were developed and meta-analyses were performed when appropriate. Read More

    Atrioesophageal Fistula Following Radiofrequency Catheter Ablation of Atrial Fibrillation.
    Rev Cardiovasc Med 2017 ;18(3):115-122
    Department of Cardiovascular Medicine, Beaumont Health, Royal Oak, MI.
    Atrioesophageal fistula (AEF) is a rare but catastrophic complication of catheter ablation of atrial fibrillation (AF), with an incidence of 0.03% to 1.5% per year. Read More

    Temperature management under general anesthesia: Compulsion or option.
    J Anaesthesiol Clin Pharmacol 2017 Jul-Sep;33(3):306-316
    Department of Neuroanaesthesiology and Critical Care, All India Institute of Medical Sciences, New Delhi, India.
    Administration of general anesthesia requires continuous monitoring of vital parameters of the body including body temperature. However, temperature continues to be one of the least seriously monitored parameters perioperatively. Inadvertent perioperative hypothermia is a relatively common occurrence with both general and regional anesthesia and can have significant adverse impact on patients' outcome. Read More

    The Implementation of Targeted Temperature Management: An Evidence-Based Guideline from the Neurocritical Care Society.
    Neurocrit Care 2017 Dec;27(3):468-487
    University of Maryland, Baltimore, MD, USA.
    Background: Targeted temperature management (TTM) is often used in neurocritical care to minimize secondary neurologic injury and improve outcomes. TTM encompasses therapeutic hypothermia, controlled normothermia, and treatment of fever. TTM is best supported by evidence from neonatal hypoxic-ischemic encephalopathy and out-of-hospital cardiac arrest, although it has also been explored in ischemic stroke, traumatic brain injury, and intracranial hemorrhage patients. Read More

    The effects of head-cooling on brain function during passive hyperthermia: an fMRI study.
    Int J Hyperthermia 2017 Nov 1:1-10. Epub 2017 Nov 1.
    b Department of Medical Imaging , Jinan Military General Hospital , Jinan , China.
    Purpose: To investigate the effect of head-cooling on resting-state spontaneous brain activity during passive hyperthermia.

    Methods: An environmental heat exposure was simulated on 16 healthy men under a normal control condition (NC) at 25 °C and two hot conditions at 50 °C with hyperthermia with head-cooling condition (HHC) and without hyperthermia condition (HOT) keeping the head cool, respectively. Resting-state functional MRI (fMRI) data were acquired under each condition and the values of amplitude low frequency fluctuations (ALFF) and z functional connectivity (zFC) were computed to examine regional activity and functional integration, respectively. Read More

    An effective thermal therapy against cancer using an E-jet 3D-printing method to prepare implantable magnetocaloric mats.
    J Biomed Mater Res B Appl Biomater 2017 Sep 15. Epub 2017 Sep 15.
    College of Biology, Hunan University, Changsha, Hunan, 410082, China.
    Magnetic hyperthermia has been rapidly developed as a potential cancer treatment in recent years. Artificially induced hyperthermia close to a tumor can raise the temperature to 45°C causing tumor cell death. Herein, we introduce a novel method for rapid preparation of anti-cancer magnetocaloric PCL/Fe3 O4 mats capable of high-performance hyperthermia using E-jet 3D printing technology. Read More

    Effectiveness of Ice-Sheet Cooling Following Exertional Hyperthermia.
    Mil Med 2017 Sep;182(9):e1951-e1957
    Exercise Science Research Center, University of Arkansas, Department of Health, Human Performance and Recreation, HPER 321, 155 Stadium Drive, Fayetteville, AR 72701.
    Background: The procedure of wrapping a heat casualty in ice-water soaked bed sheets to reduce core temperature has received little investigation, despite the practice and recommendation for its use in some military settings. Thus, the purpose of this study was to investigate the cooling efficacy of ice-sheet cooling (ISC) following exertional hyperthermia.

    Methods: 13 (11 males, 2 females) participants (age = 23 ± 3 years, height = 176. Read More

    Focused Ultrasound Hyperthermia Mediated Drug Delivery Using Thermosensitive Liposomes and Visualized With in vivo Two-Photon Microscopy.
    Theranostics 2017 7;7(10):2718-2731. Epub 2017 Jul 7.
    Physical Sciences Platform, Sunnybrook Research Institute, Toronto, ON, Canada.
    The future of nanomedicines in oncology requires leveraging more than just the passive drug accumulation in tumors through the enhanced permeability and retention effect. Promising results combining mild hyperthermia (HT) with lyso-thermosensitive liposomal doxorubicin (LTSL-DOX) has led to improved drug delivery and potent antitumor effects in pre-clinical studies. The ultimate patient benefit from these treatments can only be realized when robust methods of HT can be achieved clinically. Read More

    [Treatment of hyperthermia].
    Ugeskr Laeger 2017 Jul;179(30)
    Hyperthermia is an uncontrolled elevation of body temperature exceeding the body's ability to dissipate heat. Hyperthermia can result in dangerously high core temperatures and can rapidly become fatal. Common causes include heat stroke, malignant hyperthermia, serotonin syndrome, neuroleptic syndrome, a few endocrine emergencies as well as numerous intoxications. Read More

    Tissue shrinkage in microwave thermal ablation: comparison of three commercial devices.
    Int J Hyperthermia 2017 Aug 16:1-10. Epub 2017 Aug 16.
    b Department of Radiology , Hadassah Hebrew University, Medical Center , Jerusalem , Israel.
    Purpose: To evaluate, characterise and compare the extent of tissue shrinkage induced from three different commercial microwave ablation devices, and to elucidate the mechanism behind the distinctive performances obtained.

    Materials And Methods: Microwave ablation (N = 152) was conducted with three different commercial devices on cubes of ex vivo liver (10-40 ± 2 mm/side) embedded in agar phantoms. 50-60 W was applied for 1-10 min duration. Read More

    Randomized controlled trial of internal and external targeted temperature management methods in post- cardiac arrest patients.
    Am J Emerg Med 2018 Jan 5;36(1):66-72. Epub 2017 Jul 5.
    Department of Emergency Medicine, Singapore General Hospital, Singapore; Health Services and Systems Research, Duke-NUS Medical School, Singapore. Electronic address:
    Background: Targeted temperature management post-cardiac arrest is currently implemented using various methods, broadly categorized as internal and external. This study aimed to evaluate survival-to-hospital discharge and neurological outcomes (Glasgow-Pittsburgh Score) of post-cardiac arrest patients undergoing internal cooling verses external cooling.

    Methodology: A randomized controlled trial of post-resuscitation cardiac arrest patients was conducted from October 2008-September 2014. Read More

    Validation of a mathematical model for laser-induced thermotherapy in liver tissue.
    Lasers Med Sci 2017 Aug 22;32(6):1399-1409. Epub 2017 Jun 22.
    Institut für Diagnostische und Interventionelle Radiologie, Theodor-Stern-Kai 7, Haus 23c, 60590, Frankfurt, Germany.
    The purpose of the study was to develop a simulation approach for laser-induced thermotherapy (LITT) that is based on mathematical models for radiation transport, heat transport, and tissue damage. The LITT ablation was applied to ex vivo pig liver tissue. Experiments were repeated with different laser powers, i. Read More

    Thermal diffusivity and perfusion constants from in vivo MR-guided focussed ultrasound treatments: a feasibility study.
    Int J Hyperthermia 2017 Jun 26:1-11. Epub 2017 Jun 26.
    d Department of Radiology and Imaging Sciences , University of Utah , Salt Lake City , UT , USA.
    Purpose: This study investigates the feasibility of non-invasively determining thermal diffusivity (α) and the Pennes perfusion parameter (w) from pre-clinical and clinical magnetic resonance-guided focussed ultrasound (MRgFUS) temperature data.

    Materials And Methods: Pre-clinical MRgFUS experiments were performed in rabbit muscle (N = 3, 28 sonications) using three-dimensional MR thermometry. Eight sonications were made in a clinical QA phantom with two-dimensional thermometry. Read More

    Pilot Feasibility Study of Therapeutic Hypothermia for Moderate to Severe Acute Respiratory Distress Syndrome.
    Crit Care Med 2017 Jul;45(7):1152-1159
    1Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD.2Program in Trauma, Department of Surgery, University of Maryland School of Medicine, Baltimore, MD.3Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD.4Medicine and Research Services, Baltimore Veterans Affairs Medical Care System, Baltimore, MD.
    Objectives: Prior studies suggest hypothermia may be beneficial in acute respiratory distress syndrome, but cooling causes shivering and increases metabolism. The objective of this study was to assess the feasibility of performing a randomized clinical trial of hypothermia in patients with acute respiratory distress syndrome receiving treatment with neuromuscular blockade because they cannot shiver.

    Design: Retrospective study and pilot, prospective, open-label, feasibility study. Read More

    Effects of face/head and whole body cooling during passive heat stress on human somatosensory processing.
    Am J Physiol Regul Integr Comp Physiol 2017 Jun 12;312(6):R996-R1003. Epub 2017 Apr 12.
    Department of Health Sciences, Faculty of Human Life and Environment, Nara Women's University, Nara, Japan;
    We herein investigated the effects of face/head and whole body cooling during passive heat stress on human somatosensory processing recorded by somatosensory-evoked potentials (SEPs) at C4' and Fz electrodes. Fourteen healthy subjects received a median nerve stimulation at the left wrist. SEPs were recorded at normothermic baseline (Rest), when esophageal temperature had increased by ~1. Read More

    Effect of Antipyretic Therapy on Mortality in Critically Ill Patients with Sepsis Receiving Mechanical Ventilation Treatment.
    Can Respir J 2017 12;2017:3087505. Epub 2017 Mar 12.
    Psychological Department, The Children's Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
    Purpose. The study aimed to investigate the effectiveness of antipyretic therapy on mortality in critically ill patients with sepsis requiring mechanical ventilation. Methods. Read More

    Malignant Hyperthermia Susceptibility and Fitness for Duty.
    Mil Med 2017 Mar;182(3):e1854-e1857
    Department of Anesthesiology and Pain Medicine, 8901 Wisconsin Avenue, Walter Reed National Military Medical Center, Bethesda, MD 20889-5600.
    Introduction: Malignant hyperthermia (MH) is an inherited hypermetabolic condition characterized by uncontrolled calcium release from the sarcoplasmic reticulum of skeletal muscle, usually from exposure to inhaled general anesthetics and/or the depolarizing neuromuscular blocking agent succinylcholine. Multiple case reports now reveal that crises may be precipitated by environmental factors such as exercise or high ambient temperatures. Common signs of an MH crisis include life-threatening hyperthermia, metabolic acidosis, muscle rigidity, and tachycardia. Read More

    The typical presentation of an atypical pathogen during an outbreak of Legionnaires' disease in Vila Franca de Xira, Portugal, 2014.
    Rev Port Pneumol (2006) 2017 May - Jun;23(3):117-123. Epub 2017 Mar 1.
    Chest Department, Centro Hospitalar Lisboa Norte, Lisboa, Portugal; Institute of Environmental Health (ISAMB), Faculty of Medicine, University of Lisbon, Lisboa, Portugal.
    Background: An outbreak of Legionella pneumophila serogroup 1, with 403 cases was identified on the 7th November 2014 in Vila Franca de Xira, Portugal. Outbreak source was the wet cooling system of a local factory. Hospital Pulido Valente was one of the hospitals receiving patients with Legionnaires' disease (LD). Read More

    Increased postural sway in persons with multiple sclerosis during short-term exposure to warm ambient temperatures.
    Gait Posture 2017 Mar 8;53:230-235. Epub 2017 Feb 8.
    Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital and UT Southwestern Medical Center, Dallas, TX, USA. Electronic address:
    Background: Multiple sclerosis (MS) is a neurological disease marked by demyelination and axonal loss. Individuals with MS experience increases in clinical signs and symptoms during heat exposure.

    Objective: To test the hypothesis that moderate heat exposure adversely affects postural sway in individuals with MS. Read More

    Protocol and statistical analysis plan for the Randomised Evaluation of Active Control of Temperature versus Ordinary Temperature Management (REACTOR) trial.
    Crit Care Resusc 2017 Mar;19(1):81-87
    Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.
    Background: Body temperature can be reduced in febrile patients in the intensive care unit using medicines and physical cooling devices, but it is not known whether systematically preventing and treating fever reduces body temperature compared with standard care.

    Objective: To describe the study protocol and statistical analysis plan for the Randomised Evaluation of Active Control of Temperature versus Ordinary Temperature Management (REACTOR) trial.

    Design, Setting And Participants: Protocol for a phase II, multicentre trial to be conducted in Australian and New Zealand ICUs admitting adult patients. Read More

    Simple and effective method to lower body core temperatures of hyperthermic patients.
    Am J Emerg Med 2017 Jun 30;35(6):881-884. Epub 2017 Jan 30.
    CSA Medical, Inc., 91 Hartwell Avenue, Lexington, MA 02421, USA. Electronic address:
    Hyperthermia is a potentially life threatening scenario that may occur in patients due to accompanying morbidities, exertion, or exposure to dry and arid environmental conditions. In particular, heat stroke may result from environmental exposure combined with a lack of thermoregulation. Key clinical findings in the diagnosis of heatstroke are (1) a history of heat stress or exposure, (2) a rectal temperature greater than 40 °C, and (3) central nervous system dysfunction (altered mental state, disorientation, stupor, seizures, or coma) (Prendergast and Erickson, 2014 [1]). Read More

    Changing target temperature from 33°C to 36°C in the ICU management of out-of-hospital cardiac arrest: A before and after study.
    Resuscitation 2017 Apr 31;113:39-43. Epub 2017 Jan 31.
    Department of Epidemiology and Preventive Medicine, Monash University, Australia; The Alfred Hospital, Australia; Ambulance Victoria, Australia.
    Introduction: In December 2013, our institution changed the target temperature management (TTM) for the first 24h in ventricular fibrillation out-of-hospital cardiac arrest (VF-OHCA) patients from 33°C to 36°C. This study aimed to examine the impact this change had on measured temperatures and patient outcomes.

    Methods: We conducted a retrospective cohort study of consecutive VF-OHCA patients admitted to a tertiary referral hospital in Melbourne (Australia) between January 2013 and August 2015. Read More

    Visual function and retinal vessel diameters during hyperthermia in man.
    Acta Ophthalmol 2017 Nov 21;95(7):690-696. Epub 2016 Dec 21.
    Faculty of Health and Medical Science, University of Copenhagen, Copenhagen, Denmark.
    Purpose: To assess the effect of elevated core body temperature on temporal and spatial contrast sensitivity and retinal vessel diameters.

    Methods: The study included 13 healthy volunteers aged 20-37 years. Core body temperature elevation (target +1. Read More

    CAERvest® - a novel endothermic hypothermic device for core temperature cooling: safety and efficacy testing.
    Int J Occup Saf Ergon 2018 Mar 2;24(1):118-128. Epub 2017 Feb 2.
    a Centre for Sport and Exercise Science and Medicine (SeSAME), Environmental Extremes Laboratory , University of Brighton , UK.
    Introduction: Cooling of the body is used to treat hyperthermic individuals with heatstroke or to depress core temperature below normal for neuroprotection. A novel, chemically activated, unpowered cooling device, CAERvest®, was investigated for safety and efficacy.

    Methods: Eight healthy male participants (body mass 79. Read More

    Comparison of Two Surface Cooling Devices for Temperature Management in a Neurocritical Care Unit.
    Ther Hypothermia Temp Manag 2017 Sep 13;7(3):147-151. Epub 2016 Dec 13.
    Department of Neurology, University of Missouri , Columbia, Missouri.
    Fever increases mortality and morbidity and length of stay in neurocritically ill patients. Various methods are used in the neuroscience intensive care unit (NSICU) to control fever. Two such methods involve the Arctic Sun hydrogel wraps and the Gaymar cooling wraps. Read More

    Physiological and perceptual effects of a cooling garment during simulated industrial work in the heat.
    Appl Ergon 2017 Mar 20;59(Pt A):442-448. Epub 2016 Oct 20.
    Human Performance Laboratory, University of Arkansas, 155 Stadium Dr HPER 321, Fayetteville, AR 72701, USA. Electronic address:
    Objective: Evaluate physiological and perceptual responses using a phase change cooling (PCC) garment during simulated work in the heat.

    Methods: Twenty males wearing compression undergarments, coverall suit, gloves, and hard-hat, completed two randomly assigned trials (with PCC inserts or control, CON) of simulated industrial tasks in the heat (34.2 ± 0. Read More

    Modeling of heat transfer in a vascular tissue-like medium during an interstitial hyperthermia process.
    J Therm Biol 2016 Dec 30;62(Pt B):150-158. Epub 2016 Jun 30.
    Department of Mechanical Engineering, Isfahan University of Technology, Isfahan, Iran.
    This paper aims to evaluate the role of small vessels in heat transfer mechanisms of a tissue-like medium during local intensive heating processes, for example, an interstitial hyperthermia treatment. To this purpose, a cylindrical tissue with two co- and counter-current vascular networks and a central heat source is introduced. Next, the energy equations of tissue, supply fluid (arterial blood), and return fluid (venous blood) are derived using porous media approach. Read More

    Intravascular versus surface cooling for targeted temperature management after out-of-hospital cardiac arrest - an analysis of the TTM trial data.
    Crit Care 2016 11 26;20(1):381. Epub 2016 Nov 26.
    Department of Anesthesiology and Intensive Care, Helsingborg Hospital, Helsingborg, Sweden.
    Background: Targeted temperature management is recommended after out-of-hospital cardiac arrest and may be achieved using a variety of cooling devices. This study was conducted to explore the performance and outcomes for intravascular versus surface devices for targeted temperature management after out-of-hospital cardiac arrest.

    Method: A retrospective analysis of data from the Targeted Temperature Management trial. Read More

    Cooling Effectiveness of a Modified Cold-Water Immersion Method After Exercise-Induced Hyperthermia.
    J Athl Train 2016 Nov 22;51(11):946-951. Epub 2016 Nov 22.
    University of Arkansas, Fayetteville.
    Context:  Recommended treatment for exertional heat stroke includes whole-body cold-water immersion (CWI). However, remote locations or monetary or spatial restrictions can challenge the feasibility of CWI. Thus, the development of a modified, portable CWI method would allow for optimal treatment of exertional heat stroke in the presence of these challenges. Read More

    Tarp-Assisted Cooling as a Method of Whole-Body Cooling in Hyperthermic Individuals.
    Ann Emerg Med 2017 Mar 16;69(3):347-352. Epub 2016 Nov 16.
    Korey Stringer Institute, University of Connecticut, Storrs, CT.
    Study Objective: We investigated the efficacy of tarp-assisted cooling as a body cooling modality.

    Methods: Participants exercised on a motorized treadmill in hot conditions (ambient temperature 39.5°C [103. Read More

    Why Fever Phobia Is Still Common?
    Iran Red Crescent Med J 2016 Aug 5;18(8):e23827. Epub 2016 Jun 5.
    Department of Pediatrics, Turgut Ozal University, Ankara, Turkey.
    Background: Fever is a reliable sign of illness, but it also evokes fear and anxiety. It is not the fever itself but the fear of possible complications and accompanying symptoms that is important for pediatricians and parents.

    Objectives: We aimed to investigate maternal understanding of fever, its potential consequences, and impacts on the treatment of children. Read More

    Existence and control of Legionella bacteria in building water systems: A review.
    J Occup Environ Hyg 2017 02;14(2):124-134
    a TRC Environmental , New York , New York.
    Legionellae are waterborne bacteria which are capable of causing potentially fatal Legionnaires' disease (LD), as well as Pontiac Fever. Public concern about Legionella exploded following the 1976 outbreak at the American Legion conference in Philadelphia, where 221 attendees contracted pneumonia and 34 died. Since that time, a variety of different control methods and strategies have been developed and implemented in an effort to eradicate Legionella from building water systems. Read More

    Extracorporeal photopheresis practice patterns: An international survey by the ASFA ECP subcommittee.
    J Clin Apher 2017 Aug 21;32(4):215-223. Epub 2016 Jul 21.
    Department of Pediatrics, Ann & Robert H. Lurie Children's Hospital, Chicago, IL.
    Background: Although many apheresis centers offer extracorporeal photopheresis (ECP), little is known about current treatment practices.

    Methods: An electronic survey was distributed to assess ECP practice internationally.

    Results: Of 251 responses, 137 met criteria for analysis. Read More

    The vascular cooling effect in hepatic multipolar radiofrequency ablation leads to incomplete ablation ex vivo.
    Int J Hyperthermia 2016 Nov 11;32(7):749-56. Epub 2016 Jul 11.
    a Department of General, Visceral and Vascular Surgery , Charité - Campus Benjamin Franklin , Berlin ;
    Purpose: Major limitations of conventional RFA are vascular cooling effects. However, vascular cooling effects are supposed to be less pronounced in multipolar RFA. The objective of this ex vivo study was a systematic evaluation of the vascular cooling effects in multipolar RFA. Read More

    Thermal dysregulation in Prader-Willi syndrome: a potentially fatal complication in adolescence, not just in infancy.
    BMJ Case Rep 2016 Jun 29;2016. Epub 2016 Jun 29.
    Paediatric Intensive Care Unit, The Royal Belfast Hospital For Sick Children, Belfast, UK.
    A 13-year-old boy with a background of Prader-Willi syndrome (PWS) was admitted to the regional paediatric intensive care unit, with community-acquired pneumonia. Despite a week of intravenous antibiotics, resolution of inflammatory markers and resolving consolidation on radiograph, he remained feverish. Fever of unknown origin investigations were negative and he was diagnosed with central thermal dysregulation secondary to hypothalamic dysfunction in PWS. Read More

    Comparison of Gastrointestinal and Rectal Temperatures During Recovery After a Warm-Weather Road Race.
    J Athl Train 2016 May 17;51(5):382-8. Epub 2016 May 17.
    Korey Stringer Institute, Human Performance Laboratory, Department of Kinesiology, University of Connecticut, Storrs.
    Context: It has been well established that gastrointestinal temperature (TGI) tracks closely with rectal temperature (TREC) during exercise. However, the field use of TGI pills is still being examined, and little is known about how measurements obtained using these devices compare during recovery after exercise in warm weather.

    Objective: To compare TGI and TREC in runners who completed an 11. Read More

    Evaluation of advanced cooling therapy's esophageal cooling device for core temperature control.
    Expert Rev Med Devices 2016 May 15;13(5):423-33. Epub 2016 Apr 15.
    d Department of Emergency Medicine, Advocate Christ Medical Center , University of Illinois , Chicago, Oak Lawn , IL , USA.
    Managing core temperature is critical to patient outcomes in a wide range of clinical scenarios. Previous devices designed to perform temperature management required a trade-off between invasiveness and temperature modulation efficiency. The Esophageal Cooling Device, made by Advanced Cooling Therapy (Chicago, IL), was developed to optimize warming and cooling efficiency through an easy and low risk procedure that leverages heat transfer through convection and conduction. Read More

    Use of an Esophageal Heat Exchanger to Maintain Core Temperature during Burn Excisions and to Attenuate Pyrexia on the Burns Intensive Care Unit.
    Case Rep Anesthesiol 2016 25;2016:7306341. Epub 2016 Feb 25.
    Welsh Centre for Burns, Morriston Hospital, Swansea SA6 6NL, UK.
    Introduction. Burns patients are vulnerable to hyperthermia due to sepsis and SIRS and to hypothermia due to heat loss during excision surgery. Both states are associated with increased morbidity and mortality. Read More

    Treatment temperature and insult severity influence the neuroprotective effects of therapeutic hypothermia.
    Sci Rep 2016 Mar 21;6:23430. Epub 2016 Mar 21.
    Department of Physiology, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
    Therapeutic hypothermia (HT) is standard care for moderate and severe neonatal hypoxic-ischaemic encephalopathy (HIE), the leading cause of permanent brain injury in term newborns. However, the optimal temperature for HT is still unknown, and few preclinical studies have compared multiple HT treatment temperatures. Additionally, HT may not benefit infants with severe encephalopathy. Read More

    Intractable Central Hyperthermia in the Setting of Brainstem Hemorrhage.
    Ther Hypothermia Temp Manag 2016 Jun 16;6(2):98-101. Epub 2016 Mar 16.
    Department of Neurology, University of Texas Southwestern Medical Center , Dallas, Texas.
    Hyperthermia from a central cause is associated with increased morbidity and mortality. Dysfunction of brainstem thermoregulatory pathways may explain the intractable rise in temperature. Antipyretics, dantrolene, bromocriptine, and surface and intravascular cooling devices have been attempted for temperature control. Read More

    Dev Period Med 2015 Jul-Sep;19(3 Pt 1):247-53
    The first decade of the 21st century saw the worldwide spread of therapeutic hypothermia as a beneficial therapeutic procedure in neonates with hypoxic-ischemic encephalopathy. New guidelines for the resuscitation of newborns confirm that therapeutic hypothermia should be the standard method of treatment offered to neonates with acute perinatal hypoxia. The quality of care which an asphyxiated newborn receives during and immediately after resuscitation, as well as the mode of preparation for transport, can have a significant impact on improving the outcome, but it can also result in the deterioration of neonates treated with hypothermia. Read More

    Targeted Temperature Modulation in the Neuroscience Patient.
    Crit Care Nurs Clin North Am 2016 Mar;28(1):125-36
    Neuroscience Intensive Care Unit, Thomas Jefferson University Hospital, 111 South 11th Street, Gibbon Building, Room 9300, Philadelphia, PA 19107, USA.
    There are many approaches to and opportunities for implementing temperature modulation in critically ill patients, but barriers also exist. Conceptually, the process of cooling is rather straightforward; however, targeted temperature management is anything but simplistic. The need for a collaborative approach (physicians champions, nursing support, respiratory therapists, pharmacists, laboratory personnel, and supply chain representatives) to address definitions of normothermia and fever, patient inclusion/exclusion criteria for therapy based on underlying neurorelated pathologies, determination of methods of induction/maintenance, monitoring required, education planning, and strategies to minimize potential complications are warranted. Read More

    Prognostic factors associated with hospital survival in comatose survivors of cardiac arrest.
    World J Crit Care Med 2016 Feb 4;5(1):103-10. Epub 2016 Feb 4.
    Kushaharan Sathianathan, Critical Care Unit, Latrobe Regional Hospital, Traralgon, VIC 3844, Australia.
    Aim: To identify patient, cardiac arrest and management factors associated with hospital survival in comatose survivors of cardiac arrest.

    Methods: A retrospective, single centre study of comatose patients admitted to our intensive care unit (ICU) following cardiac arrest during the twenty year period between 1993 and 2012. This study was deemed by the Human Research Ethics Committee (HREC) of Monash Health to be a quality assurance exercise, and thus did not require submission to the Monash Health HREC (Research Project Application, No. Read More

    Temperature and blood flow distribution in the human leg during passive heat stress.
    J Appl Physiol (1985) 2016 May 28;120(9):1047-58. Epub 2016 Jan 28.
    Centre for Human Performance, Exercise and Rehabilitation, Brunel University London, Uxbridge, United Kingdom
    The influence of temperature on the hemodynamic adjustments to direct passive heat stress within the leg's major arterial and venous vessels and compartments remains unclear. Fifteen healthy young males were tested during exposure to either passive whole body heat stress to levels approaching thermal tolerance [core temperature (Tc) + 2°C; study 1; n = 8] or single leg heat stress (Tc + 0°C; study 2; n = 7). Whole body heat stress increased perfusion and decreased oscillatory shear index in relation to the rise in leg temperature (Tleg) in all three major arteries supplying the leg, plateauing in the common and superficial femoral arteries before reaching severe heat stress levels. Read More

    Effects of mild hypohydration on cooling during cold-water immersion following exertional hyperthermia.
    Eur J Appl Physiol 2016 Apr 18;116(4):687-95. Epub 2016 Jan 18.
    University of Arkansas, 155 Stadium Dr HPER 321, Fayetteville, AR, 72701, USA.
    Purpose: We investigated the effects of mild hypohydration compared to euhydration on the cooling efficacy of cold-water immersion (CWI).

    Methods: Fourteen participants (eight male, six female; age 26 ± 5 years; ht 1.77 ± 0. Read More

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