192,097 results match your criteria Conversion Disorder
Cell Physiol Biochem 2018 Dec 6;51(5):2065-2072. Epub 2018 Dec 6.
Department of General Surgery of East District, The Second Hospital of Hebei Medical University, Shijiazhuang,
Background/aims: Disseminated tumors, known as metastases, are responsible for ninety-percent of mortality due to cancer. Epithelial to mesenchymal transition, a phenomenon required for morphological conversion of non-motile discoid shaped epithelial cells to highly motile spindle-shaped mesenchymal cells, is thought to be a pre-requisite for metastatic progression. Metastasis-associated 1 (MTA1) protein is a prime inducer of EMT and metastatic progression in all solid tumors including hepatocellular carcinoma (HCC). Read More
J Environ Manage 2018 Dec 3;232:615-624. Epub 2018 Dec 3.
Division of Environmental and Water Resources Engineering, School of Civil and Environmental Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798, Singapore; Residues and Resource Reclamation Centre, Nanyang Environment and Water Research Institute, Nanyang Technological University, 1 Cleantech Loop, Singapore 637141, Singapore.
With increasing demand for biodiesel, crude glycerol as a by-product in biodiesel production has been generated and oversupplied. This study, therefore, explored the pretreatment and a subsequent two-stage microbial system to convert crude glycerol into high value-added products: 1,3-propanediol (1,3-PDO) and polyhydroxyalkanoates (PHAs). After pretreatment, long chain fatty acids (LCFAs) could be effectively removed from crude glycerol to eliminate the inhibition effects on subsequent microbial process. Read More
PLoS One 2018 6;13(12):e0208430. Epub 2018 Dec 6.
Swine Technical Services, Zoetis, Parsippany, New Jersey, United States of America.
The trial objective was to compare the performance and animal health parameters of pigs raised according to one of 3 antibiotic (AB) protocols: standard AB medication consisting of mass treatment on days 4 and 21 and judicious AB therapy given therapeutically thereafter as group medication in water and feed or by individual injection (group T1, N = 702); modified AB medication identical to group T1 but with mass treatment only on day 4 and without subsequent therapeutic feed medication (group T2, N = 675); or an antibiotic-free (ABF) regimen (group T3, N = 702). All pigs were vaccinated with a modified-live porcine reproductive and respiratory syndrome virus (PRRSV) vaccine 3 days after weaning. Using a seeder pig model to mimic endemic field infection dynamics, pigs were contact-challenged with virulent PRRSV lineage 1 strain 174 four weeks after vaccination. Read More
ACS Nano 2018 Dec 6. Epub 2018 Dec 6.
Application of transition metal phosphides (TMPs) for electrochemical energy conversion and storage has great potential to alleviate the energy crisis. Although there are various methods to obtain TMPs, it is still immensely challenging to fabricate hierarchical porous TMPs with superior electrochemical performances by a simple, green and secure method. We herein describe a facile approach for fabricating CoP/C nanoboxes by pyrolyzing phytic acid (PA) cross-linked Co complexes that acquired from reaction of PA and ZIF-67. Read More
Inorg Chem 2018 Dec 6. Epub 2018 Dec 6.
State Key Laboratory of Powder Metallurgy , Central South University , Changsha , Hunan 410083 , P. R. China.
Layered transition-metal oxides are one kind of the most promising cathode materials for sodium-ion batteries. In this study, we propose a strategy to enhance the electrochemical properties of P3-type manganese-based layered oxide cathode by introducing a small amount of layered P2 and Li-O'3 phases. Powder X-ray diffraction (PXRD) structural refinement and aberration-corrected scanning transmission electron microscopy (STEM) are performed to confirm the microstructures of different samples. Read More
Int Braz J Urol 2018 Oct 30;44. Epub 2018 Oct 30.
Divisão de Urologia do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brasil.
Objectives: Nephrectomy due to stone disease may be a challenging procedure owing to the presence of significant inflammation and infection, involving high complication rate. The objective of our study was to identify predictors for complications of nephrectomy for urolithiasis.
Patients And Methods: A retrospective review of 149 consecutive patients > 18y submitted to simple nephrectomy for urolithiasis from January 2006 to July 2012 was performed. Read More
Chemistry 2018 Dec 6. Epub 2018 Dec 6.
Kings College London, Department of Imaging Chemistry and Biology, St Thomas' Hospital, SE1 7EH, London, UNITED KINGDOM.
Aldehyde dehydrogenases (ALDHs) catalyze the oxidation of aldehydes to carboxylic acids, with elevated ALDH expression in human cancers linked to metastases and poor overall survival. Despite ALDH being a poor prognostic factor, the non-invasive assessment of ALDH activity in vivo has not been possible due to a lack of sensitive and translational imaging agents. In this report, we present the synthesis and biological evaluation of ALDH1A1-selective chemical probes composed of an aromatic aldehyde derived from N,N-diethylamino benzaldehyde (DEAB) linked to a fluorinated pyridine ring either via an amide or amine linkage. Read More
Radiat Prot Dosimetry 2018 Dec 6. Epub 2018 Dec 6.
Physikalisch-Technische Bundesanstalt (PTB), Bundesallee 100, Braunschweig, Germany.
In Report No. 90 of the International Commission on Radiation Units and Measurements (ICRU), new mass energy-absorption coefficients are listed which are based on renormalized Scofield photoeffect cross-sections. The mass energy-absorption coefficients are the basis for the conversion coefficients from air kerma to the operational quantities listed in ISO 4037-3. Read More
Chem Commun (Camb) 2018 Dec 6. Epub 2018 Dec 6.
Key Laboratory of Artificial Micro/Nano Structures of Ministry of Education, School of Physics and Technology, Wuhan University, Wuhan, 430072, China.
An inorganic caesium cation was incorporated into perovskite to improve the performance and stability of solar cells with a hole-transport-material free structure in ambient air. A triple cation device with a champion power conversion efficiency of over 15% was achieved, exhibiting superior thermal, long-term and operational stabilities. Read More
Ther Drug Monit 2018 Dec 4. Epub 2018 Dec 4.
Department of Pharmacy, Shanghai Changhai Hospital, Second Military Medical University, Shanghai (200433), China.
Background: Kidney transplant recipients on long-term cyclosporine (CsA) therapy may develop multiple adverse drug events, and immunosuppression conversion from CsA to tacrolimus (Tac) is an option. Genetic variations, especially cytochrome P450 (CYP) 3A5*3 affects Tac dosing. However, little information is available to guide the conversion with regards to patients' pharmacogenomics. Read More
Surg Laparosc Endosc Percutan Tech 2018 Dec 4. Epub 2018 Dec 4.
Department of Surgery, Royal Derby Hospital, Uttoxeter Road, Derby, UK.
Background: The incidence of common bile duct (CBD) stones is between 10% to 18% in people undergoing cholecystectomy for gallstones. Laparoscopic exploration of the CBD is now becoming routine practice in the elective setting, however its safety and efficacy in emergencies is poorly understood.
Methods: We analyzed our results for index emergency admission laparoscopic cholecystectomy within a specialist center in the United Kingdom. Read More
Org Lett 2018 Dec 6. Epub 2018 Dec 6.
TU Braunschweig, Institute of Organic Chemistry , Hagenring 30 , 38106 Braunschweig , Germany.
Wang's enantioselective thiourea-catalyzed spiro-annulation paved the way to the first tetracyclic analog of the marine natural product cyanogramide from the actinobacterium Actinoalloteichus cyanogriseus. The synthesis comprises seven steps starting from an alkylidene indolinone. Installation of the ( E)-styryl side chain faced a regiochemistry problem, circumvented by prior conversion to the hydantoin and employing Batey's conditions. Read More
ACS Appl Mater Interfaces 2018 Dec 6. Epub 2018 Dec 6.
Heretofore, conjugated polymers (CPs) attract considerable attention in photothermal therapy (PTT). Although various CPs with different structures have been reported, the suboptimal circulation persistence and biodistribution limit their efficacy in tumor treatment. Human serum albumin (HSA), an endogenous plasm protein, has been widely functioned as a carrier for therapeutic agents. Read More
ACS Appl Mater Interfaces 2018 Dec 6. Epub 2018 Dec 6.
Metal borides represent an emerging family of advanced electrocatalyst for oxygen evolution reaction (OER). Herein, we present a fast and simple method of synthesizing iron-doped amorphous nickel boride on reduced graphene oxide (rGO) sheets. The hybrid exhibits outstanding OER performance and stability in prolonged OER operation. Read More
Chemphyschem 2018 Dec 6. Epub 2018 Dec 6.
Boreskov Institute of Catalysis RAS, pr. Lavrenteva 5, 630000, Novosibirsk, RUSSIAN FEDERATION.
Colloidal catalysts for water oxidation to dioxygen, which are stable on storage and under the reaction conditions, are synthesized based on CoIII, MnIII, FeIII and CuII hydroxides. Stabilization of the colloids with dextrated starch allows the process of hydroxide ageing to be stopped at the stage of the formation of primary nuclei (ca. 2-3 nm from TEM data). Read More
J Esthet Restor Dent 2018 Dec 6. Epub 2018 Dec 6.
Q LAB, Perth, Western Australia, Australia.
Objective: To report an alternative clinical and laboratory protocol for same-day implant fixed full-arch provisional rehabilitation that may overcome limitations associated with traditional immediate provisional denture conversion rehabilitation protocols.
Clinical Considerations: The traditional denture conversion fabrication method of an immediate full-arch fixed provisional involves the conversion of a complete denture into a provisional fixed implant-support prosthesis. The conversion technique has several shortcomings which compromise structural integrity, longevity, ease of modification, and the need for a silicone impression. Read More
Photochem Photobiol Sci 2018 Dec 6. Epub 2018 Dec 6.
College of Chemistry, and State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, Jilin University, Changchun, Jilin 130012, China.
Under hydro(solvo)thermal conditions, four organic bidentate bridging N,N'-donor ligands 1,3-bis(2-methylimidazol-1-yl)propane (L1), 4,4'-di(1H-imidazol-1-yl)-1,1'-biphenyl (L2), 1,2-bis(2-methyl-1H-imidazol-1-ylmethyl)benzene (L3) and 5,6,7,8-tetrahydroquinoxaline (L4) were employed to react with CuBr/CuI, generating four 2-D layered copper(i)-polymer coordination polymer materials [Cu2Br2(L1)] 1, [CuI(L2)] 2, [CuI(L3)] 3 and [CuI(L4)0.5] 4. In 1-4, different Cu-X motifs are found: a cubic Cu4Br4 core in 1; a castellated Cu-I single chain in 2; a rhombic Cu2I2 core in 3; and a staircase-like Cu-I double chain in 4. Read More
Dalton Trans 2018 Dec 6. Epub 2018 Dec 6.
Institute of New Energy Technology, College of Information Science and Technology, Jinan University, Guangzhou 510632, PR China.
Renewable energy utilization by energy conversion devices is regarded as a promising solution to resolve energy crisis and environmental pollution problems. Solar energy occupies 99% of the total energy of the Earth; therefore, the development of photovoltaic technology to convert solar energy into electricity is attracting considerable interests. The state-of-the-art research in this field mainly focuses on the improvement of power conversion efficiency under the sunlight irradiation by new materials development, device structure optimization, technique innovation, etc. Read More
Nanotechnology 2019 Feb;30(5):055602
Applied Chemistry Key Lab of Hebei Province, Department of Bioengineering, Yanshan University, Qinhuangdao 066004, People's Republic of China. Asparagus Industry Technology Research Institute of Hebei Province, Qinhuangdao 066004, People's Republic of China.
A new type of vapreotide-templated Ag/Au bimetallic nanoshells (Vap@Ag/AuNSs) were successfully designed and fabricated based on polypeptide-directed mineralization and hierarchical self-assembly mechanisms under mild synthetic conditions. The nanoparticles with polypeptides serving as a core and coated Ag/Au bimetallic nanoshells exhibit diverse advantages, such as excellent biocompatibility, tumor targeting and low-cost. The Vap@Ag/AuNSs share excellent dispersibility, uniform size (120 nm) and a positive zeta potential (36. Read More
ACS Appl Mater Interfaces 2018 Dec 6. Epub 2018 Dec 6.
Chlorobenzene and diethyl ether were chosen as anti-solvent to control the crystallization of CH3NH3PbI3. Under the condition of similar crystallization for both perovskite films, the obvious larger short circuit current density for CH3NH3PbI3 film treated by chlorobenzene prompted us to unveil the roles of chlorobenzene in the perovskite films via adjusting the dipping amount of chlorobenzene. A novel insight of chlorobenzene function was revealed, i. Read More
Angew Chem Int Ed Engl 2018 Dec 6. Epub 2018 Dec 6.
National Institute of Advanced Industrial Science and Technology (AIST), 1-8-31 Midorigaoka, , 563-8577, Ikeda, JAPAN.
Large carbon networks featuring hierarchical pores and atomically dispersed metal sites (ADMSs) are ideal materials for energy storage and conversion due to the spatial-continuous conductive networks and highly active ADMSs. However, it is a challenge to synthesize such ADMS-decorated carbon networks. Here, we innovatively present a fusion-foaming methodology to puff up energetic metal-organic framework (EMOF) nanoparticles to submillimetric ADMS-decorated carbon networks via one-step pyrolysis. Read More
Chem Asian J 2018 Dec 5. Epub 2018 Dec 5.
Fudan University, Department of Chemistry, 220 Handan Road, 200433, Shanghai, CHINA.
We report tunable supramolecular self-assemblies formed by water-soluble pillar[n]arenes (WPns, n = 5-7) and bipyridinium-azobenzene guests. Nanoscale or microscale morphology of self-assemblies in water was controlled by host size of WPn. Supramolecular self-assemblies could undergo morphology conversion under UV-irradiation. Read More
Chemistry 2018 Dec 6. Epub 2018 Dec 6.
School of Materials Science and Engineering and, Guangdong Provincial Key Laboratory of, Advanced Energy Storage Materials, South China University of, Technology, Guangzhou, 510641, P.R. China.
Amorphous nanoparticles of ZnO and TiO embedded in carbon nanocages (AZT⊂CNCs) were successfully synthesized through a simple annealing process of TiO -coated zeolitic imidazolate framework-8 (ZIF-8). In the current anode of AZT⊂CNCs, tiny ZnO and TiO nanoparticles were uniformly distributed in the carbon matrix (carbon nanocages), which could effectively buffer the volume expansion of electroactive ZnO and provide excellent electric conductivity. After fully investigating the electrochemical performance of the AZT⊂CNCs samples obtained with different additive amounts of tetrabutyl orthotitanate (TBOT) for TiO coating, it has been found that AZT-30 (0. Read More
EJNMMI Res 2018 Dec 5;8(1):107. Epub 2018 Dec 5.
Imaging Technology Group, GE Healthcare, The Grove Centre, White Lion Road, Amersham, Buckinghamshire, UK.
Introduction: A standardised method for quantifying β-amyloid PET tracers would allow comparison across different tracers and different sites. The development of the Centiloid scale has aimed to achieve this, applying a common scale to better aid the diagnosis and prognosis of Alzheimer's disease (AD) and to monitor anti-amyloid therapeutic interventions. Here, we apply the Centiloid method to [F]flutemetamol and [C]PiB (PiB, Pittsburgh compound B) PET images and derive the scaling factor to express their binding in Centiloids. Read More
World J Urol 2018 Dec 5. Epub 2018 Dec 5.
USC Institute of Urology, Keck Medicine of USC, University of Southern California, Los Angeles, CA, USA.
Objectives: To determine and investigate the intraoperative factors that contribute to a change in plan from continent orthotopic neobladder to ileal conduit or continent cutaneous diversion at the time of radical cystectomy.
Subjects And Methods: A retrospective review of our prospectively maintained bladder cancer database was performed. Of the 711 patients who underwent radical cystectomy from 2012 to 2016, 387 (54. Read More
Phys Chem Chem Phys 2018 Dec 6. Epub 2018 Dec 6.
L3 - Luminescent Lanthanide Lab, Department of Chemistry, Ghent University, Krijgslaan 281-S3, B-9000 Ghent, Belgium.
In this work, we prepared a novel kind of Yb3+,Er3+/Ho3+ co-doped CsGd(MoO4)2 phosphors with a different structure from the reported ALn(MoO4)2 (A = Li, Na or K; Ln = La, Gd or Y) compounds using a high-temperature solid-state reaction method. X-ray diffraction showed that the as-prepared samples had a pure phase. Based on the efficient energy transfer from Yb3+ to Er3+/Ho3+, the up-conversion (UC) luminescence of the optimal CsGd(MoO4)2:0. Read More
Technology (Singap World Sci) 2018 Jun 29;6(2):67-74. Epub 2018 Jun 29.
Department of Biomedical Engineering, Rutgers, the State University of New Jersey, 599 Taylor Road, Piscataway, NJ 08854, USA.
Allergic contact dermatitis (ACD) is an inflammatory disease that impacts 15-20% of the general population and accurate screening methods for chemical risk assessment are needed. However, most approaches poorly predict pre- and pro-hapten sensitizers, which require abiotic or metabolic conversion prior to inducing sensitization. We developed a tri-culture system comprised of MUTZ-3-derived Langerhans cells, HaCaT keratinocytes, and primary dermal fibroblasts to mimic the cellular and metabolic environments of skin sensitization. Read More
Front Chem 2018 21;6:548. Epub 2018 Nov 21.
Metagenomics and Secretomics Research Laboratory, Department of Botany, Dr. Harisingh Gour Central University, Sagar, India.
Water hyacinth (WH) is a troublesome aquatic weed of natural and artificial water bodies of India and other tropical countries and causing severe ecological problems. The WH biomass is low in lignin content and contains high amount of cellulose and hemicellulose, making it suitable material for conversion into liquid fuels for energy production. This study highlighted that, how different imidazolium based ionic liquids (ILs) [1-alkyl-3-methylimidazolium bromide, [Cmim]Br ( = 2, 4, 6, 8, and 10)] with tunable properties can be employed for the degradation of WH biomass. Read More
Front Chem 2018 16;6:541. Epub 2018 Nov 16.
Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan, China.
Dye-sensitized solar cell (DSSC) has been attractive to scientific community due to its eco-friendliness, ease of fabrication, and vivid colorful property . Among various kinds of sensitizers, such as metal-free organic molecules, metal-complex, natural dyes ., porphyrin is one of the most promising sensitizers for DSSC. Read More
J Cancer 2018 22;9(23):4398-4403. Epub 2018 Oct 22.
Department of Gastrointestinal Surgery, China-Japan Union Hospital of Jilin University, No. 126 Xiantai Street, Changchun, 130000, People's Republic of China.
The purpose of this study was to compare the short- and long-term outcomes after laparoscopic total gastrectomy (LTG) between elderly and non-elderly patients with gastric cancer. A retrospective analysis was performed using clinical and follow-up data from 168 patients treated with LTG for gastric cancer at our institution from January 2010 to December 2017. For this study, the short- and long-term outcomes (including tumor recurrence rate, disease-free survival rate, and overall survival rate) were compared between the elderly group (≥70 years) and non-elderly group (<70 years). Read More
Biotechnol Biofuels 2018 30;11:319. Epub 2018 Nov 30.
Department of Chemical and Materials Engineering, University of Kentucky, 177 F Paul Anderson Tower, Lexington, KY 40506 USA.
Background: Effective enzymatic degradation of crystalline polysaccharides requires a synergistic cocktail of hydrolytic enzymes tailored to the wide-ranging degree of substrate crystallinity. To accomplish this type of targeted carbohydrate recognition, nature produces multi-modular enzymes, having at least one catalytic domain appended to one or more carbohydrate binding modules (CBMs). The Type B CBM categorization encompasses several families (i. Read More
Front Microbiol 2018 21;9:2822. Epub 2018 Nov 21.
State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China.
() is a zoonotic parasite that severely harms the health of the host. The cysts of can reactivate from bradyzoites to tachyzoites, if the individual develops low or defective immunity, causing lethal toxoplasmosis. The host resists infection by mediating Th1-type cellular immunity to generate pro-inflammatory cytokines. Read More
J Pestic Sci 2018 Nov;43(4):314-320
Department of Environmental Sciences, Faculty of Life and Environmental Sciences, University of Yamanashi, 4-4-37 Takeda, Kofu, Yamanashi, Japan.
An aerobic dieldrin-degrading fungus, strain DDF, and two aerobic endosulfan-degrading fungal strains, sp. strains W8 and Cm1-45, were isolated from soil contaminated with organochlorine pesticides. Strain DDF degraded more than 90% dieldrin during 10-days of incubation at 25°C and showed the production of a small amount of aldrin -diol. Read More
Nat Commun 2018 Dec 5;9(1):5183. Epub 2018 Dec 5.
State Key Laboratory of Catalysis, Dalian National Laboratory for Clean Energy, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China.
Selective conversion of an aqueous solution of mixed oxygenates produced by biomass fermentation to a value-added single product is pivotal for commercially viable biomass utilization. However, the efficiency and selectivity of the transformation remains a great challenge. Herein, we present a strategy capable of transforming ~70% of carbon in an aqueous fermentation mixture (ABE: acetone-butanol-ethanol-water) to 4-heptanone (4-HPO), catalyzed by tin-doped ceria (Sn-ceria), with a selectivity as high as 86%. Read More
Sci Rep 2018 Dec 5;8(1):17633. Epub 2018 Dec 5.
Department of Mechanical Engineering, Birla Institute of Technology and Science - Pilani, Hyderabad Campus, Jawahar Nagar, Kapra Mandal, Medchal District, 500078, Telangana, India.
Understanding the role of graphene in the thermal stability and pore morphology of polymer derived silicon oxycarbide is crucial for electrochemical energy storage and hydrogen storage applications. Here in this work, we report the synthesis of graphene nanoplatelets dispersed silicon oxycarbide ceramics by the polymer to ceramic synthesis route. Samples containing graphene and without graphene are subjected to different pyrolysis conditions and are characterized using FT-IR, XPS, Raman spectroscopy, XRD, FE-SEM, HR-TEM, and BET. Read More
Nature 2018 Dec 5. Epub 2018 Dec 5.
Department of Developmental Biology, Washington University School of Medicine in St Louis, St Louis, MO, USA.
Direct lineage reprogramming involves the conversion of cellular identity. Single-cell technologies are useful for deconstructing the considerable heterogeneity that emerges during lineage conversion. However, lineage relationships are typically lost during cell processing, complicating trajectory reconstruction. Read More
J Cell Sci 2018 Dec 5. Epub 2018 Dec 5.
Department of Cardiology, The Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University Wenzhou 325000, Zhejiang Province China
Mitochondria are important for energy production and cardiomyocytes homeostasis. OMA1, a metalloendopeptidase, initiates the proteolytic process of pro-fusion protein, OPA1, to deteriorate mitochondrial structure and function. In this study, mouse embryonic fibroblasts (MEFs) and neonatal mouse cardiomyocytes (NMCMs) subjected to hypoxia-reperfusion (H/R) and/or HO were used to mimic oxidative stress in the heart following ischemia-reperfusion (I/R). Read More
Ultrason Sonochem 2019 Mar 5;51:469-477. Epub 2018 Jul 5.
Nanomaterials and Solar Energy Conversion Lab, Department of Chemistry, National Institute of Technology, Tiruchirappalli 620 015, India. Electronic address:
Here in, we report a simple and facile method to synthesis morphology oriented transition metal (Nickel) doped polyaniline (Ni/PANI) by chemical oxidative polymerization with the assistance of ultrasonic irradiation. Physicochemical property of the materials examined through XRD and FT-IR. The morphological feature exposed that the sonochemical assisted Ni doped PANI is differing from the conventional method and it reveals a notable electrochemical property as in the form of specific capacitance (370 F g at 0. Read More
J Biomater Sci Polym Ed 2018 Dec 5:1-26. Epub 2018 Dec 5.
a College of Materials Science and Engineering, South China University of Technology , Guangzhou , 510641 , China.
A new urethane dimethacrylate TMA was synthesized through a typical urethane reaction. TMA was used to replace 1,6-bis(methacryloxy-2-ethoxycarbonyl- amino)-2,4,4- trimethylhexane (UDMA) in UDMA based composite partially or totally to prepare TMA containing composites. Critical properties of TMA containing composites were investigated. Read More
ACS Appl Mater Interfaces 2018 Dec 6. Epub 2018 Dec 6.
Metal fluorides have usually a large electronegativity and are promising electrode materials for high power lithium-ion batteries. However, like other conversion reaction based materials, large volumetric expansions and large capacity losses in cycling are major issues for metal fluorides. Here, we explore substitution of Ni with Cu for binary NiF2 and its effects to the electrochemical properties. Read More
Nanomaterials (Basel) 2018 Dec 4;8(12). Epub 2018 Dec 4.
Realtek Semiconductor Corp., No. 2, Innovation Road II, Hsinchu Science Park, Hsinchu 300, Taiwan.
In this study, we sought to enhance the output power and conversion efficiency of textured silicon solar cells by layering two-dimensional indium nanoparticles (In NPs) within a double-layer (SiN/SiO₂) antireflective coating (ARC) to induce plasmonic forward scattering. The plasmonic effects were characterized using Raman scattering, absorbance spectra, optical reflectance, and external quantum efficiency. We compared the optical and electrical performance of cells with and without single layers and double layers of In NPs. Read More
J Microbiol Biotechnol 2018 Nov 28. Epub 2018 Nov 28.
College of Chemistry and Chemical Engineering, Hunan Institute of Engineering, Xiangtan 411104, P. R. China.
To investigate a novel β-glucosidase from ATCC 15700 (BbBgl) to produce compound K (CK) via ginsenoside F by highly selective and efficient hydrolysis of the C-3 glycoside from ginsenoside Rd. gene was cloned and expressed in BL21. The recombinant BbBgl was purified by Ni-NTA magnetic beads to obtain an enzyme with specific activity of 37 U/mg protein using NP-Glc as substrate. Read More
J Mol Graph Model 2018 Nov 26;87:76-88. Epub 2018 Nov 26.
Department of Pharmacoinformatics, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S. Nagar, Punjab, 160 062, India; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sector 67, S.A.S. Nagar, Punjab, 160 062, India. Electronic address:
The substrate to the enzyme PfDHFR (Plasmodium falciparum Dihydrofolate Reductase) is a small molecule dihydrofolate (DHF), it gets converted to tetrahydrofolate (THF) in the active site of the enzyme. The PfDHFR reaction surface involves the protonation of DHF to DHFP as an initial step before the catalytic conversion. The binding affinities of all these species (DHF, DHFP and THF) contribute to the mechanism of DHFR catalytic action. Read More
Mol Cell Endocrinol 2018 Nov 30. Epub 2018 Nov 30.
Division of Metabolism, Endocrinology, & Diabetes, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA; Department of Pharmacology, University of Michigan, Ann Arbor, MI, USA.
17β-hydroxysteroid dehydrogenase type 3 (17βHSD3) deficiency is an autosomal recessive disorder of male sex development that results in defective testosterone biosynthesis. Although mutations in the cognate HSD17B3 gene cause a spectrum of phenotypic manifestations, the majority of affected patients are genetic males having female external genitalia. Many cases do not present until puberty, at which time peripheral conversion of androgen precursors causes progressive virilization. Read More
Neurochem Int 2018 Nov 30. Epub 2018 Nov 30.
Department of Immunology, National Institute of Neuroscience, National Center of Neurology and Psychiatry (NCNP), 4-1-1 Ogawahigashi, Kodaira, Tokyo, 187-8502, Japan. Electronic address:
Reserch progresses in understanding the pathogenicity of multiple sclerosis (MS) in the last couple of decade has enabled us to develop new drug entities available in the clinic. However, we still have not succeeded in preventing conversion from relapsing-remitting MS (RR-MS) to secondary progressive MS (SP-MS) and curing this intractable form of MS. Furthermore, diagnosis is usually retrospective and subjective, relying on gradual worsening of neurological signs/symptoms. Read More
ACS Appl Mater Interfaces 2018 Dec 3. Epub 2018 Dec 3.
Phototherapy, as an important class of noninvasive tumor treatment methods, has attracted extensive research interest. Although a large amount of the near-infrared (NIR) phototherapeutic agents have been reported, the low efficiency, complicated structures, tedious synthetic procedures, and poor photostability limit their practical applications. To solve these problems, herein, a donor-acceptor-donor (D-A-D) type organic phototherapeutic agent (B-3) based on NIR aza-boron-dipyrromethene (aza-BODIPY) dye has been constructed, which shows the enhanced photothermal conversion efficiency and high singlet oxygen generation ability by simultaneously utilizing intramolecular photoinduced electron transfer (IPET) mechanism and heavy atom effects. Read More
ACS Nano 2018 Dec 3. Epub 2018 Dec 3.
As one of the most remarkable oxygen evolution reaction (OER) electrocatalysts, metal chalcogenides have been intensively reported due to their high OER activities during the past few decades. It has been reported that electron-chemical conversion of metal chalcogenides into oxides/hydroxides would take place after OER. However, the transition mechanism of such unstable structures, as well as the real active sites and catalytic activity during OER for these electrocatalysts, has not been understood yet, which urgently needs a direct observation for the electrocatalytic water oxidation process, especially at nano or even angstrom scale. Read More
Angew Chem Int Ed Engl 2018 Dec 3. Epub 2018 Dec 3.
Hebrew University of Jerusalem, Institute of Chemistry, Aronberg 128, 9190401, Jerusalem, ISRAEL.
The origin of the spectral shift from a red- to a green-absorbing form in a cyanobacteriochrome, Slr1393g3, is identified by application of combined quantum mechanics/molecular mechanics simulations. This protein, related to classical phytochromes, carries the open-chain tetrapyrrole chromophore phycocyanobilin. Our calculations reveal that the effective conjugation length in the chromophore becomes shorter upon conversion from the red to the green form. Read More
Chem Asian J 2018 Dec 3. Epub 2018 Dec 3.
Institute for Superconducting and Electronic Materials, ISEM, Wollongong, 2519, Wollongong, AUSTRALIA.
Electrochemical water splitting for hydrogen generation is a vital part for the prospect of future energy system, however, the practical utilization relies on the development of highly active and earth-abundant catalysts to boost the energy conversion efficiency as well as reduce the cost. Molybdenum diselenide (MoSe2) is a promising nonprecious metal-based electrocatalyst for hydrogen evolution reaction (HER) in acidic media, but it exhibits inferior alkaline HER kinetics in great part due to the sluggish water adsorption/dissociation process. Herein, the alkaline HER kinetics of MoSe2 is substantially accelerated by heteroatom doping with transition metal ions. Read More