714 results match your criteria Contact Stomatitis

Comparison of Endemic and Epidemic Vesicular Stomatitis Virus Lineages in Midges.

Viruses 2022 Jun 3;14(6). Epub 2022 Jun 3.

Arthropod-Borne Animal Diseases Research Unit, Center for Grain and Animal Health, Agricultural Research Service, United States Department of Agriculture, Manhattan, KS 66502, USA.

Vesicular stomatitis virus (VSV) primarily infects livestock and is transmitted by direct contact and vectored by midges (Diptera: Ceratopogonidae). Endemic to Central and South America, specific VSV lineages spread northward out of endemic regions of Mexico and into the U.S. Read More

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Photobiomodulation Therapy in the Treatment of Oral Mucositis-A Case Report.

Medicina (Kaunas) 2022 Apr 29;58(5). Epub 2022 Apr 29.

Department of Oral Surgery, Medical University of Wroclaw, 50-425 Wroclaw, Poland.

In 2021, our group published a laboratory study on the impact of PBM on human gingival fibroblasts. The in vitro results confirmed the fact that the appropriately selected wavelength and properly selected parameters of the laser settings can increase cell proliferation, modulate inflammatory markers, and decrease the susceptibility of human gingival fibroblasts to apoptosis. Therefore, this case report was aimed at the clinical evaluation of the proposed settings and treatment regimen in a very difficult situation of an immunocompromised patient with extensive changes and stagnation of symptoms for many weeks. Read More

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Efficacy of GMI, a fungal immunomodulatory protein, for head and neck cancer patients with chemotherapy-related oral mucositis: An open-labeled prospective single-arm study.

Medicine (Baltimore) 2022 Apr 22;101(16):e29185. Epub 2022 Apr 22.

School of Medicine, Chung Shan Medical University, Taichung, Taiwan.

Background: Cancer patients usually suffer from intensive chemotherapy-related oral mucositis (OM), yet limited effective treatment can rapidly alleviate OM severity.

Methods: This prospective study examined the efficacy of Reishimmune-S containing one fungal immunomodulatory protein, GMI on OM in patients with head and neck cancer. Patients with head and neck cancer and the diagnosis of chemotherapy-related OM were enrolled randomizedly to receive standard supportive care with/without Reishimmune-S 500 mg/day orally for consecutive 14 days. Read More

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Hydrophobicity of Denture Base Resins: A Systematic Review and Meta-analysis.

J Int Soc Prev Community Dent 2022 Mar-Apr;12(2):139-159. Epub 2022 Apr 8.

Department of Dental Education, College of Dentistry, Imam Abdulrahman Bin Faisal University, P. O. Box 1982, Dammam 31441, Saudi Arabia.

Objectives: The aim of this article is to review the factors that attract to denture base resin (DBR) and to verify the influence of different surface treatments, chemical modification, or structural reinforcements on the properties of DBR.

Materials And Methods: Searches were carried out in PubMed, Scopus, WOS, Google Scholar, EMBASE, and J-stage databases. The search included articles between 1999 and 2020. Read More

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Allergic contact stomatitis due to desensitizing toothpastes.

J Dermatol 2022 Jun 8;49(6):648-651. Epub 2022 Mar 8.

Department of Oral Medicine, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology & Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health & NMPA Key Laboratory for Dental Materials, Beijing, China.

Toothpastes are one of the most common personal care products among people of all ages. The various toothpaste types and their complex ingredients could cause irritation or allergic reactions. Allergic contact stomatitis has been often seen in clinical practice; however, desensitizing toothpastes as a trigger are often unrecognized. Read More

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Skin tests in the work-up of cutaneous adverse drug reactions: A review and update.

Contact Dermatitis 2022 May 9;86(5):344-356. Epub 2022 Mar 9.

Sorbonne Université, INSERM 1135 Cimi-Paris, Hôpital Tenon, Assistance Publique-Hôpitaux de Paris, Département de dermatologie et d'allergologie, Paris, France.

Skin tests, including patch tests (PTs), prick tests, and intradermal tests (IDTs), are useful in identifying the culprits of cutaneous adverse drug reactions (CADRs), and determining safer, alternative drugs. PTs have a low sensitivity but are valuable in investigating maculopapular exanthema (MPE), as well as severe CADR, including toxic epidermal necrolysis (TEN), Stevens-Johnson syndrome (SJS), and in particular, acute generalized exanthematous pustulosis (AGEP), and drug reaction with eosinophilia and systemic symptoms (DRESS). To ensure their specificity, at least 10 control tests should be performed. Read More

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[Mucoperiodontal lesions: improvement of prosthodontic treatment considering initial indicators of patients' oral health].

Stomatologiia (Mosk) 2021 ;100(6. Vyp. 2):22-28

E.A. Vagner Perm State Medical University, Perm, Russia.

Objective: To assess the need for prosthodontic treatment and to substantiate the features and perspectives for optimizing prosthodontic treatment in patients with mucoperiodontal manifestations of lichen planus (LP).

Material And Methods: For assessment of the need and identification of problematic aspects of prosthetic treatment 74 patients (48.3% of the primary sample of all patients with oral LP) with oral LP-associated mucoperiodontal lesions (MPL) participated in a multicenter open cohort prospective controlled clinical trial with elements of retrospective analysis. Read More

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January 2022

Comment on: "Varenicline-induced erosive stomatitis: First case report".

Esen Özkaya

Contact Dermatitis 2022 04 7;86(4):331. Epub 2022 Feb 7.

Department of Dermatology and Venereology, İstanbul Faculty of Medicine, İstanbul University, Istanbul, Turkey.

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Denture Acrylic Resin Material with Antibacterial and Protein-Repelling Properties for the Prevention of Denture Stomatitis.

Polymers (Basel) 2022 Jan 7;14(2). Epub 2022 Jan 7.

Department of Advanced Oral Sciences and Therapeutics, School of Dentistry, University of Maryland, Baltimore, MD 21201, USA.

Denture stomatitis is a multifactorial pathological condition of the oral mucosa that affects up to 72% of denture wearers. It is commonly seen on the palatal mucosa and characterized by erythema on the oral mucosa that are in contact with the denture surface. The aim of this study was to incorporate 2-methacryloyloxyethyl phosphorylcholine (MPC) and dimethylaminohexadecyl methacrylate (DMAHDM) into a high impact polymethylmethacrylate heat-cured denture base acrylic resin as a potential treatment for denture stomatitis. Read More

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January 2022

Adsorptive Inhibition of Enveloped Viruses and Nonenveloped Cardioviruses by Antiviral Lignin Produced from Sugarcane Bagasse via Microwave Glycerolysis.

Biomacromolecules 2022 03 17;23(3):789-797. Epub 2022 Jan 17.

Laboratory of Biomass Conversion, Research Institute for Sustainable Humanosphere, Kyoto University, Gokasho, Uji, Kyoto 611-0011, Japan.

Antiviral lignin was produced by acidic microwave glycerolysis of sugarcane bagasse. The lignin exhibited antiviral activity against nonenveloped (encephalomyocarditis virus (EMCV) and Theiler's murine encephalomyelitis virus (TMEV)) and enveloped (vesicular stomatitis virus (VSV), Sindbis virus (SINV), and Newcastle disease virus (NDV)) viruses. A series of lignins with different antiviral activities were prepared by reacting bagasse at 140, 160, 180, and 200 °C to analyze the antiviral mechanism. Read More

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Broad virus inactivation using inorganic micro/nano-particulate materials.

Mater Today Bio 2022 Jan 22;13:100191. Epub 2021 Dec 22.

Microbiology Section, Dpto. CC, Farmacéuticas y de la Salud, Facultad de Farmacia, Universidad San Pablo-CEU, 28668, Madrid, Spain.

Inorganic materials can provide a set of tools to decontaminate solid, liquid or air containing viral particles. The use of disinfectants can be limited or not practical in scenarios where continuous cleaning is not feasible. Physicochemical differences between viruses raise the need for effective formulations for all kind of viruses. Read More

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January 2022

Toxic epidermal necrolysis during camrelizumab treatment for esophageal squamous cell carcinoma.

Contact Dermatitis 2022 05 17;86(5):417-419. Epub 2022 Jan 17.

Department of Cancer Center, Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.

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Varenicline-induced erosive stomatitis: First case report.

Contact Dermatitis 2022 Apr 3;86(4):317-318. Epub 2022 Jan 3.

Department of Allergy, La Paz University Hospital, Madrid, Spain.

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Highly efficient intercellular spreading of protein misfolding mediated by viral ligand-receptor interactions.

Nat Commun 2021 10 19;12(1):5739. Epub 2021 Oct 19.

German Center for Neurodegenerative Diseases Bonn (DZNE), Venusberg Campus 1/ 99, 53127, Bonn, Germany.

Protein aggregates associated with neurodegenerative diseases have the ability to transmit to unaffected cells, thereby templating their own aberrant conformation onto soluble homotypic proteins. Proteopathic seeds can be released into the extracellular space, secreted in association with extracellular vesicles (EV) or exchanged by direct cell-to-cell contact. The extent to which each of these pathways contribute to the prion-like spreading of protein misfolding is unclear. Read More

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October 2021

Aerosol SARS-CoV-2 in hospitals and long-term care homes during the COVID-19 pandemic.

PLoS One 2021 30;16(9):e0258151. Epub 2021 Sep 30.

National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Canada.

Background: Few studies have quantified aerosol concentrations of SARS-CoV-2 in hospitals and long-term care homes, and fewer still have examined samples for viability. This information is needed to clarify transmission risks beyond close contact.

Methods: We deployed particulate air samplers in rooms with COVID-19 positive patients in hospital ward and ICU rooms, rooms in long-term care homes experiencing outbreaks, and a correctional facility experiencing an outbreak. Read More

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October 2021

Ethosuximide-induced Stevens-Johnson syndrome/toxic epidermal necrolysis overlap confirmed by patch testing in a child.

Contact Dermatitis 2021 Nov 16;85(5):602-604. Epub 2021 Jul 16.

Dermatology Department, Coimbra University Hospital Center, Coimbra, Portugal.

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November 2021

In Vitro Assessment of Artificial Aging on the Antifungal Activity of PMMA Denture Base Material Modified with ZrO Nanoparticles.

Int J Dent 2021 13;2021:5560443. Epub 2021 May 13.

Department of Substitutive Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 41441, Saudi Arabia.

The antifungal effect of zirconium dioxide nanoparticles (ZrONPs) incorporated into denture base material has been inadequately investigated; additionally, to the authors' knowledge, no studies have assessed the influence of artificial aging on the antifungal activity of these particles. . Heat-polymerized acrylic resin disks were fabricated and divided into four groups (0%, 1%, 2. Read More

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Histopathologic Spectrum of Intraoral Irritant and Contact Hypersensitivity Reactions: A Series of 12 cases.

Head Neck Pathol 2021 Dec 26;15(4):1172-1184. Epub 2021 Apr 26.

Department of Oral Medicine Infection and Immunity, Harvard School of Dental Medicine, 188 Longwood Avenue, Boston, MA, 02115, USA.

Background: Irritant contact stomatitis (ICS) and contact hypersensitivity stomatitis (CHS) are often caused by alcohol, flavoring agents and additives in dentifrices and foods, and contactants with high or low pH. A well-recognized contactant for ICS is Listerine™ mouthwash, while that for CHS is cinnamic aldehyde. However, many other flavoring agents and even smokeless tobacco are contactants that cause mucosal lesions that are entirely reversible. Read More

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December 2021

Recurrent Aphthous Stomatitis Improved after Eradication Therapy for .

Case Rep Gastrointest Med 2021 30;2021:5543838. Epub 2021 Mar 30.

Gastroenterology Department, Loma Linda University Medical Center, Loma Linda, CA, USA.

(. ) is a Gram-negative bacterium that colonizes gastric mucosa and is often transmitted through direct contact with saliva, contaminated food or water, and vomit. The majority of the infected individuals remain asymptomatic for a long period. Read More

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High dose of vesicular stomatitis virus-vectored Ebola virus vaccine causes vesicular disease in swine without horizontal transmission.

Emerg Microbes Infect 2021 Dec;10(1):651-663

Department of Diagnostic Medicine/Pathobiology, Center of Excellence for Emerging and Zoonotic Animal Diseases (CEEZAD), College of Veterinary Medicine, Kansas State University, Manhattan, KS, USA.

The recent impact of Ebola virus disease (EVD) on public health in Africa clearly demonstrates the need for a safe and efficacious vaccine to control outbreaks and mitigate its threat to global health. ERVEBO® is an effective recombinant Vesicular Stomatitis Virus (VSV)-vectored Ebola virus vaccine (VSV-EBOV) that was approved by the FDA and EMA in late 2019 for use in prevention of EVD. Since the parental virus VSV, which was used to construct VSV-EBOV, is pathogenic for livestock and the vaccine virus may be shed at low levels by vaccinated humans, widespread deployment of the vaccine requires investigation into its infectivity and transmissibility in VSV-susceptible livestock species. Read More

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December 2021

Corneal ectasia with Stevens-Johnson syndrome.

Clin Exp Optom 2021 May 1;104(4):535-537. Epub 2021 Mar 1.

Institute of Health & Biomedical Innovation and School of Optometry and Vision Science, Queensland University of Technology, Kelvin Grove, Australia.

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Antifungal property of acrylic denture soft liner containing silver nanoparticles synthesized in situ.

J Dent 2021 03 29;106:103589. Epub 2021 Jan 29.

Department of Prosthodontics, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, 210008, China. Electronic address:

Objectives: Denture soft liner is applied to relieve pain from candida-induced denture stomatitis and promote healing, but with shortage of antifungal activity and easily harbors fungi. To overcome this problem, the in-situ method was used to synthesize silver nanoparticles (AgNPs) in acrylic soft liner to obtain antifungal effects.

Methods: Acrylic soft-liner with various weight percentage of silver 2-ethylhexanoate (0%, 0. Read More

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Effect of Denture Base Fabrication Technique on Adhesion In Vitro.

Materials (Basel) 2021 Jan 5;14(1). Epub 2021 Jan 5.

Department of Prosthodontics, Goldschleger School of Dental Medicine, Sackler Faculty of Medicine, Tel-Aviv University, Ramat-Aviv 69978, Israel.

Denture stomatitis is a common manifestation of oral candidiasis affecting some 65% of denture wearers. This condition is initiated by the adherence of to denture base acrylic resin. The present study aimed to test the in vitro effect of traditional and novel fabrication methods on adhesion to denture base samples. Read More

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January 2021

Comparison of patients' diagnoses in a dermatology outpatient clinic during the COVID-19 pandemic period and pre-pandemic period.

Int J Clin Pract 2021 Apr 26;75(4):e13948. Epub 2020 Dec 26.

Department of Biostatistics and Medical Informatics, Medical Faculty, Inonu University, Malatya, Turkey.

Aim: In this study, we compared the current diagnoses of patients admitted to the dermatology outpatient clinic with the diagnoses during the non-pandemic period, and we examined the effect of COVID-19 on the patient profile.

Methods: Diagnoses were compared by examining the patient files of the 3-month period when the pandemic was influential in our country and the 2-week non-pandemic period corresponding to the same season a year ago. The outpatient diagnoses in the first month and the last month of the 3-month pandemic period were also compared. Read More

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Antifungal and Surface Properties of Chitosan-Salts Modified PMMA Denture Base Material.

Molecules 2020 Dec 13;25(24). Epub 2020 Dec 13.

Department of Experimental Dentistry, Faculty of Dentistry, Wroclaw Medical University, 26 Krakowska st., 50-425 Wroclaw, Poland.

Chitosan (CS) and its derivatives show antimicrobial properties. This is of interest in preventing and treating denture stomatitis, which can be caused by fungi. Therefore, the aim of this study was the development of a novel antifungal denture base material by modifying polymethyl methacrylate (PMMA) with CS-salt and characterizing its antifungal and surface properties in vitro. Read More

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December 2020

Allergic Contact Cheilitis and Stomatitis Due to Triclosan in Toothpaste.

Kalman L Watsky

Dermatitis 2021 Jan-Feb 01;32(1):e15-e16

From the Yale University School of Medicine, Yale-New Haven Hospital, CT.

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October 2021

Validation of a binary ethylenimine (BEI) inactivation procedure for biosafety treatment of foot-and-mouth disease viruses (FMDV), vesicular stomatitis viruses (VSV), and swine vesicular disease virus (SVDV).

Vet Microbiol 2021 Jan 16;252:108928. Epub 2020 Nov 16.

Foreign Animal Disease Diagnostic Laboratory, National Veterinary Services Laboratories, Animal and Plant Health Inspection Service, United States Department of Agriculture, Plum Island Animal Disease Center, 40550 Route 25, Orient Point, NY 11957, USA. Electronic address:

Binary ethylenimine (BEI) has been widely used as a virucide to inactivate viruses. For regulatory exclusion of a select agent, the United States Federal Select Agent Program (FSAP) requires an inactivation procedure that renders a select agent non-viable but allows the select agent to retain antigenic characteristics for future use must be validated, and the inactivated agent must be confirmed by a viability testing. In this curve-based validation study, we examined impacts of BEI concentration, treatment temperature, and time on our in-house inactivation procedures of Foot-and-Mouth Disease Virus (FMDV), Vesicular Stomatitis Virus (VSV), and Swine Vesicular Disease Virus (SVDV). Read More

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January 2021

Oral Mucosal Epithelial Transplantation and Limbal-Rigid Contact Lens: A Therapeutic Modality for the Treatment of Severe Ocular Surface Disorders.

Cornea 2020 Nov;39 Suppl 1:S19-S27

Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.

Stevens-Johnson syndrome, ocular cicatricial pemphigoid, and severe thermal or chemical injury are considered severe ocular surface disorders (OSDs) because they affect the entire ocular surface, including corneal and conjunctival epithelial stem cells. In patients with severe OSDs, the long-term prognosis for limbal transplantation is poor, and the related corneal opacity and cicatrization lead to devastating visual impairment. To date, there is no standardized treatment to improve vision in cases with severe OSD. Read More

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November 2020

Development of Spray Formulations Applied to the Oral Mucosa Using Non-lamellar Liquid Crystal-Forming Lipids.

Chem Pharm Bull (Tokyo) 2020 ;68(11):1025-1033

Faculty of Pharmacy and Pharmaceutical Sciences, Josai University.

We examined the physicochemical and biochemical properties of mono-O-(5,9,13-trimethyl-4-tetradecenyl)glycerol ester (MGE), including ease of handling, high bioadhesiveness, quick and stable in vivo self-organization (forming a non-lamellar lyotropic liquid crystal [NLLC]), and high biomembrane permeation enhancement. We prepared MGE oral mucosa-applied spray preparations containing triamcinolone acetonide (TA), which is widely used in the treatment of stomatitis, and we examined the usefulness of the MGE preparations compared with commercially available oral mucosal application preparations containing 2,3-dihydroxypropyl oleate (1-mono(cis-9-octadecenoyl)glycerol (GMO) (previously studied as an NLLC-forming lipid) preparation. As a result, the MGE preparation applied to the oral mucosa can rapidly formed an NLLC with reverse hexagonal or cubic structures, or a mixture, on contact with water. Read More

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