1,138 results match your criteria Contact Lens and Anterior Eye[Journal]


Effects of scleral-lens oxygen transmissibility on corneal thickness: A pilot study.

Cont Lens Anterior Eye 2019 Apr 15. Epub 2019 Apr 15.

Clinical Research Center, School of Optometry, University of California, Berkeley, United States; Vision Science Graduate Program, University of California, Berkeley, United States. Electronic address:

Purpose: To investigate the effect of various oxygen transmissibilities (Dk/t) of scleral lenses and corneal thickness recovery time from overnight eye closure with patching on corneal edema during 5 h lens wear.

Methods: Scleral lenses (hofocon A, 15.6 mm diameter) were worn bilaterally with three different Dks (100, 140, and 160 Barrer). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13670484183080
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http://dx.doi.org/10.1016/j.clae.2019.04.002DOI Listing
April 2019
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Clinical features of Streptococcus pyogenes keratitis: Case series.

Cont Lens Anterior Eye 2019 Apr 12. Epub 2019 Apr 12.

University of Pittsburgh Medical Centre, Pittsburgh, PA, USA; Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address:

Purpose: To characterize the risk factors, clinical presentations, management, outcomes, and microbiological properties of Streptococcus pyogenes keratitis.

Methods: Eight culture-proven cases (eight eyes) of S. pyogenes keratitis were diagnosed and treated between 2008 and 2018 at the University of Pittsburgh Medical Center (UPMC). Read More

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http://dx.doi.org/10.1016/j.clae.2019.04.007DOI Listing

The influence of meibomian gland loss on ocular surface clinical parameters.

Cont Lens Anterior Eye 2019 Apr 10. Epub 2019 Apr 10.

Optometry and Vision Department, Faculty of Optics and Optometry, Complutense University of Madrid, Madrid, Spain.

Purpose: To assess the relationship between the meibomian gland loss (MGL) and relevant ocular surface clinical parameters as well as the influence of age in this relationship.

Methods: A total of 161 participants (mean age; 42±17 years) were enrolled in this study. Infrared meibography was performed using Keratograph 5M (K5M; Oculus GmbH, Wetzlar). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13670484183106
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http://dx.doi.org/10.1016/j.clae.2019.04.004DOI Listing
April 2019
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A topographical method to quantify scleral contact lens decentration.

Cont Lens Anterior Eye 2019 Apr 10. Epub 2019 Apr 10.

Contact Lens and Visual Optics Laboratory, School of Optometry and Vision Science, Queensland University of Technology, Australia.

Purpose: To describe a simple method to quantify scleral contact lens decentration using over-topography captured with a Placido ring videokeratoscope, and its repeatability.

Methods: Scleral lens over-topography (E300 videokeratoscope, Medmont) was measured on 10 healthy participants following 15 min of lens settling (16.5 mm total diameter ICD miniscleral, Capricornia). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13670484183097
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http://dx.doi.org/10.1016/j.clae.2019.04.005DOI Listing
April 2019
4 Reads

Colonization of therapeutic contact lens by dematiaceous fungi.

Cont Lens Anterior Eye 2019 Apr 10. Epub 2019 Apr 10.

Department of Cornea and Refractive Services, Aravind Eye Hospital 1, Anna Nagar, Madurai, 625020, Tamil Nadu, India.

Purpose: To report 2 patients with colonization of therapeutic contact lens with dematiaceous fungi.

Methods: Case report.

Results: The first patient had a retained soft contact lens on an opaque cornea for 4 years with brownish black multiple colonies on the soft contact lens and culture grew Bipolaris spp. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13670484183104
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http://dx.doi.org/10.1016/j.clae.2019.04.008DOI Listing
April 2019
1 Read

Corneal surface wettability and tear film stability before and after scleral lens wear.

Cont Lens Anterior Eye 2019 Apr 6. Epub 2019 Apr 6.

Department of Optics II (Optometry and Vision), Faculty of Optic and Optometry, Universidad Complutense de Madrid, Madrid, Spain. Electronic address:

Purpose: The aim of this study was to evaluate the anterior surface of scleral contact lens and ocular surface wettability before and after one-month of scleral lens wear in patients with keratoconus.

Methods: Forty-nine patients with keratoconus (36.26 ± 9. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13670484183102
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http://dx.doi.org/10.1016/j.clae.2019.04.001DOI Listing
April 2019
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Quantification of contact lens wettability after prolonged visual device use under low humidity conditions.

Cont Lens Anterior Eye 2019 Apr 3. Epub 2019 Apr 3.

Alcon Research, Ltd., 11460 Johns Creek Parkway, Johns Creek, GA, USA.

Purpose: Discomfort of silicone hydrogel (SiHy) contact lenses (CL) is associated with longer wearing time, demanding visual tasks, and dry environments. This study investigated the impact of challenging environmental conditions on thewettability of four daily disposable SiHy CL.

Methods: Habitual wearers of delefilcon A (n=32) and somofilcon A (n=32) were tested with their habitual lenses and with stenfilcon A and narafilcon A lenses. Read More

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http://dx.doi.org/10.1016/j.clae.2019.03.004DOI Listing

Toxicity of therapeutic contact lenses based on bacterial cellulose with coatings to provide transparency.

Cont Lens Anterior Eye 2019 Apr 1. Epub 2019 Apr 1.

São Paulo State University (UNESP), School of Dentistry, Rua Humaitá, 1680 (street), 14801-903, Araraquara, São Paulo, Brazil. Electronic address:

Therapeutic contact lenses were developed from bacterial cellulose (BC) by the Institute of Chemistry at Brazil's São Paulo State University (UNESP). In a previous study, cyclodextrins (CD) and medications such as ciprofloxacin (CP) and diclofenac sodium (DS) were incorporated into the lenses to provide therapeutic properties and control drug release. However, significant opacity was seen in the material inherent to cellulose. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13670484183098
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http://dx.doi.org/10.1016/j.clae.2019.03.006DOI Listing
April 2019
4 Reads

Evaluation of dry eye disase and meibomian gland dysfunction with meibography in seborrheic dermatitis.

Cont Lens Anterior Eye 2019 Mar 25. Epub 2019 Mar 25.

Aksaray Training and Research Hospital, Ophthalmology Department, Aksaray, Turkey.

Purpose: To evaluate the dry eye disase and meibomian gland dysfunction with meibography of Seborrheic Dermatit patients.

Methods: A hundred-ten of 50 patients with Seborrheic Dermatitis (group 1) and 100 eyes of 50 healthy individuals (group 2) were enrolled in this prospective study. All subjects were performed a comprehensive ophthalmic examination including lid margin alterations and meibomian gland obstruction assessment, Ocular Surface Disease Index assessment, tear film break-up time test, corneal and conjunctival fluorescein staining assessment, Schirmer test. Read More

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http://dx.doi.org/10.1016/j.clae.2019.03.005DOI Listing
March 2019
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Orthokeratology lens for management of myopia in anisometropic children: A contralateral study.

Cont Lens Anterior Eye 2019 Mar 22. Epub 2019 Mar 22.

The First Affiliated Hospital of Chongqing Medical University, Chongqing, PR China; Chongqing Key Laborary of Ophthalmology and Chongqing Eye Institute, Chongqing, PR China.

Purpose: To investigate the effect of overnight orthokeratology (OK) lens wear on axial growth in anisometropic children.

Methods: The study involved 17 males and 12 females with an average age of 11.4 ± 2. Read More

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http://dx.doi.org/10.1016/j.clae.2019.03.003DOI Listing
March 2019
2.000 Impact Factor

Translation and validation of the 8-item Contact Lens Dry Eye Questionnaire (CLDEQ-8) among Japanese soft contact lens wearers: The J-CLDEQ-8.

Cont Lens Anterior Eye 2019 Mar 16. Epub 2019 Mar 16.

Department of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan.

Purpose: To translate and validate a Japanese version of the 8-item Contact Lens Dry Eye Questionnaire (CLDEQ-8) among a multicenter sample of Japanese-speaking soft contact lens (SCL) wearers in Japan.

Methods: The study comprised two phases, 1) forward and backward translation of the CLDEQ-8 into Japanese, 2) cross-sectional validation of Japanese CLDEQ-8 (J-CLDEQ-8) among Japanese spherical disposable SCL wearers (daily disposable, 2 week, or monthly disposable) against their Overall Opinion of SCLs, and 3) repeatability testing in a subset of subjects.

Results: 300 subjects (118 males and 182 females) completed the J-CLDEQ-8 and anchoring Gestalt SCL questions. Read More

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http://dx.doi.org/10.1016/j.clae.2019.03.002DOI Listing
March 2019
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A study of contact lens compliance in a non-clinical setting.

Cont Lens Anterior Eye 2019 Mar 16. Epub 2019 Mar 16.

The Ohio State University College of Optometry, 338 W 10th Ave, Columbus, OH 43210, United States.

Purpose: To evaluate soft contact lens replacement, overnight (ON) wear, and contact lens case compliance in a non-clinical sample.

Methods: Subjects (n = 297) were recruited at the Center for Science and Industry (COSI) in Columbus, Ohio. Adult (≥ 18 years) soft contact lens wearers completed a survey about contact lens replacement, ON contact lens wear, and contact lens case replacement habits. Read More

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http://dx.doi.org/10.1016/j.clae.2019.03.001DOI Listing
March 2019
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Eye care professionals' perceptions of the benefits of daily disposable silicone hydrogel contact lenses.

Cont Lens Anterior Eye 2019 Mar 13. Epub 2019 Mar 13.

Clinical Research Scientist and Consultant, Berkeley, CA, USA; School of Optometry, University of California, Berkeley. CA, USA. Electronic address:

Purpose: To gain a better understanding of eye care professionals' (ECPs) perceptions regarding the benefits of silicone hydrogel (SiH) daily disposable contact lenses (DDCL), particularly with respect to health, comfort and patient satisfaction.

Methods: A survey was conducted with 300 ECPs in the United States, United Kingdom and Japan during November 2017. The survey comprised 34 statements relating to SiH DDCLs, to which the ECPs provided their level of agreement using a 6 point Likert scale. Read More

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http://dx.doi.org/10.1016/j.clae.2019.02.012DOI Listing
March 2019
2 Reads

Antimicrobial and physicomechanical natures of silver nanoparticles incorporated into silicone-hydrogel films.

Cont Lens Anterior Eye 2019 Feb 28. Epub 2019 Feb 28.

Department of Polymers and Pigments, National Research Centre, Dokki, Cairo, Egypt.

Purpose: The effects of silver nanoparticles (AgNPs) incorporated in silicone-hydrogel films on their physicochemical properties and microbial activity were investigated.

Methods: Silicone-hydrogel composite films (SiHCFs) were prepared by in-situ chemical reduction of silver ions added in different concentrations (0, 10, 20, 30, 40, 60, and 80 ppm) followed by ultraviolet (UV) casting. The reduction of silver ions into AgNPs was confirmed by transmission electron microscopy (TEM) and absorption spectroscopy over ultraviolet and visible (UV-vis) wavelengths. Read More

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http://dx.doi.org/10.1016/j.clae.2019.02.007DOI Listing
February 2019
6 Reads

The ocular surface status in individuals having long-term exposure to ionizing X-radiations.

Cont Lens Anterior Eye 2019 Feb 26. Epub 2019 Feb 26.

Department of Medical Surgical Nursing, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Purpose: The present investigation was done to assess the status of tear film and corneal topography in individuals with long-term exposure to X-ray.

Method: This historical cohort study was carried out to compare the lacrimal and corneal findings between radiographers (n = 126) and non-radiographers (n = 172). Radiographers included individuals with at least 5 years of experience in radiography while subjects in the control group had no history of exposure to X-ray. Read More

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http://dx.doi.org/10.1016/j.clae.2019.02.009DOI Listing
February 2019
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2.000 Impact Factor

Performance and predictability of a new large diameter contact lens design in keratoconic corneae.

Cont Lens Anterior Eye 2019 Feb 26. Epub 2019 Feb 26.

Centro Fernández-Velazquez, C./Matilde Landa, 16, Madrid, Spain. Electronic address:

Objectives: To evaluate the clinical performance and predictability using corneal topography in the fitting of a new large-diameter rigid gas permeable (RGP) contact lens design in eyes with keratoconus (KCN).

Methods: This study presents a review of eyes fitted with Alexa ES lenses for nonsurgical optimisation of visual correction. Anterior steep simulated keratometry (sim-K steep), corneal diameter (HVID), the Curvature at the apex in diopters (Cc), and distance from the corneal apex to the centre of the cornea (Lc) in millimetres derived from the Cone Location and Magnitude Index (CLMI) were recorded. Read More

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http://dx.doi.org/10.1016/j.clae.2019.02.014DOI Listing
February 2019
5 Reads

Pre-contact lens and pre-corneal tear film kinetics.

Cont Lens Anterior Eye 2019 Feb 25. Epub 2019 Feb 25.

OCULAR TECHNOLOGY GROUP - International, London, UK.

Purpose: Contact lenses (CL) insulate the corneal surface from the environment. It is possible that they influence the corneal sensory mechanism that contribute to spontaneous blinking. The study objective was to quantify the pre-CL and pre-corneal tear film kinetics (TFK) over blink period. Read More

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http://dx.doi.org/10.1016/j.clae.2019.02.001DOI Listing
February 2019
5 Reads

Is there scope for expanding the optometrist's scope of practice in Singapore? - A survey of optometrists, opticians in Singapore.

Cont Lens Anterior Eye 2019 Feb 25. Epub 2019 Feb 25.

Implementation Science, The University of Adelaide, Adelaide, Australia.

Purpose: In Singapore, optometrists' roles are limited compared to their counterparts elsewhere. The purpose of the survey is to investigate optometrists' current roles, views on extended roles, self-reported primary eye care knowledge, needs for continuing professional education (CPE) and views on suitable modes for CPE.

Methods: Members of the Optometrist and Optician Board (OOB) were invited via email to take part in an anonymous online survey. Read More

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http://dx.doi.org/10.1016/j.clae.2019.02.008DOI Listing
February 2019

Atomic force microscopy analysis of the effect of plasma treatment on gas permeable contact lens surface topography.

Cont Lens Anterior Eye 2019 Feb 23. Epub 2019 Feb 23.

Cardiff University, School of Optometry and Vision Sciences, Cardiff, UK; University of Waterloo, School of Optometry and Vision Science, Waterloo, Canada. Electronic address:

Purpose: Using atomic force microscopy (AFM) to investigate anterior surface topography (AST) in worn and unworn, plasma surface-treated (PST) and untreated (UT) gas permeable (GP) lenses, and influence of surface topography on in vivo comfort.

Methods: GP lens AST evaluated with AFM in tapping mode, using an uncoated, 40 nm symmetric tip (sampling frequency: 300 kHz), at five randomised locations, over a 100μm area, to produce mean average roughness (Ra) and root mean square (RMS) values for each sample. Four unworn lenses (two PST, two UT) were examined (Quasar/Boston EO material). Read More

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http://dx.doi.org/10.1016/j.clae.2019.02.010DOI Listing
February 2019

Disease patterns of microbial keratitis in Singapore: A retrospective case series.

Cont Lens Anterior Eye 2019 Feb 23. Epub 2019 Feb 23.

Department of Ophthalmology, National University Hospital, 5 Lower Kent Ridge Road, 119074, Singapore. Electronic address:

Purpose: To investigate the disease patterns of Microbial Keratitis(MK) in patients seen in a tertiary referral hospital, to evaluate the clinical outcomes of MK and the risk factors for poorer visual outcomes.

Methods: This is a retrospective case series of all culture-positive corneal scrapings between April 2012 and October 2016. A total of 230 patients(n = 230) were included into this study. Read More

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http://dx.doi.org/10.1016/j.clae.2019.02.006DOI Listing
February 2019
2.000 Impact Factor

Clinical evaluation of different types of contact lenses in keratoconus management.

Cont Lens Anterior Eye 2019 Feb 23. Epub 2019 Feb 23.

Yıldırım Beyazıt University, Ankara Atatürk Training and Research Hospital, Ophthalmology Department, Üniversiteler Mahallesi Bilkent Caddesi No: 1, Ankara, Turkey. Electronic address:

Purpose: To compare the clinical and topographical findings of the keratoconus patients according to the prescribed contact lens type and to investigate the effects of corneal collagen cross-linking (CXL) and cone location on lens selection.

Methods: The records of 301 eyes of 195 keratoconus patients who were prescribed contact lenses were analyzed retrospectively. The eyes were grouped according to the lens type: Soft toric contact lens (STCL), rigid gas-permeable contact lens (RGPCL), hybrid contact lens (HCL) and mini-scleral contact lens (MSCL). Read More

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http://dx.doi.org/10.1016/j.clae.2019.02.013DOI Listing
February 2019

Scleral publications & contact lens category growth.

Authors:
Ian Davies

Cont Lens Anterior Eye 2019 Apr 22;42(2):234-235. Epub 2019 Feb 22.

IansEyes Ltd. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S13670484193004
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http://dx.doi.org/10.1016/j.clae.2019.02.005DOI Listing
April 2019
3 Reads

IACLE: Yesterday, today and tomorrow.

Cont Lens Anterior Eye 2019 Apr 21;42(2):129-131. Epub 2019 Feb 21.

Aston University, School of Life and Health Sciences, B4 7ET, UK. Electronic address:

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http://dx.doi.org/10.1016/j.clae.2019.02.003DOI Listing
April 2019
1 Read

Reply to the Letter to the Editor.

Authors:
Pinar Kosekahya

Cont Lens Anterior Eye 2019 Apr 15;42(2):233. Epub 2019 Feb 15.

Department of Ophthalmology, Division of Cornea and Contact Lens, Ulucanlar Eye Training and Research Hospital, Ankara, Turkey. Electronic address:

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http://dx.doi.org/10.1016/j.clae.2019.02.004DOI Listing
April 2019
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Pentacam and vector analysis to evaluate longitudinal corneal tomographical changes in non-progressive keratoconus eyes.

Cont Lens Anterior Eye 2019 Apr 14;42(2):232. Epub 2019 Feb 14.

Department of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, Baronissi, SA, Italy.

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http://dx.doi.org/10.1016/j.clae.2019.02.002DOI Listing
April 2019
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Rigid gas permeable contact lenses for visual rehabilitation of unilateral aphakic children in China.

Cont Lens Anterior Eye 2018 Dec 28. Epub 2018 Dec 28.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China. Electronic address:

Purpose: To investigate the effectiveness, safety and tolerance of rigid gas-permeable contact lenses (RGP CLs) in the visual rehabilitation of unilateral aphakic children in China.

Methods: Records of 36 children (36 eyes) with RGP CLs to unilateral aphakia between 2014 and 2018 were evaluated. Each enrolled child underwent vision assessment (visual acuity, fixation, and deviation) at each follow-up visit and their caregivers completed a questionnaire designed to find out the reasons for RGP CLs dropout. Read More

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http://dx.doi.org/10.1016/j.clae.2018.12.009DOI Listing
December 2018
2 Reads

A novel method in correcting aberropia using pin hole soft contact lenses: A case report.

Cont Lens Anterior Eye 2018 Dec 26. Epub 2018 Dec 26.

Ahalia School of Optometry, Ahalia Foundation Eye Hospital, Palakkad 678557, India. Electronic address:

Aberropia leads to decrease in image quality due to higher order aberrations (HOA). Correction of these HOA poses a great challenge to clinicians. A case report is presented here where a 30 year old male visited with complaints of cloudy vision, diplopia in reduced illumination along with inferior vertical elongation of light during night time in the right eye since 6 years. Read More

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http://dx.doi.org/10.1016/j.clae.2018.12.007DOI Listing
December 2018
1 Read

Randomized crossover trial of silicone hydrogel contact lenses.

Cont Lens Anterior Eye 2018 Dec 23. Epub 2018 Dec 23.

Department of Optometry and Vision, Faculty of Optics and Optometry, Complutense University of Madrid, Madrid, Spain.

Purpose: The aim of the current study is to assess, using new technologies, the interaction of four monthly silicone hydrogel contact lenses on the ocular surface and the comfort over 15 days of use.

Methods: Prospective cross-over, randomized and double-masked study including four materials (lotrafilcon-B, samfilcon-A , comfilcon-A and filcom-V3). Clinical examination was performed in the following order: tear meniscus height, first break-up of the tear film, the average time of all tear film breakup incidents, bulbar redness, limbal redness (Keratograph 5M ,Oculus, Germany); central corneal thickness (Pentacam, Oculus, Germany), thermography values (FLIR A325; FLIR Systems Inc. Read More

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http://dx.doi.org/10.1016/j.clae.2018.12.006DOI Listing
December 2018
3 Reads

Impact of soft contact lenses on lid- parallel conjunctival folds.

Cont Lens Anterior Eye 2018 Dec 18. Epub 2018 Dec 18.

Dr. Heiko Pult - Optometry and Vision Research, Weinheim, Germany.

Purpose: Lid-parallel conjunctival folds (LIPCOF) are related to dry eye symptoms and appear to be related to mechanical forces in blinks. The primary aim of this longitudinal, parallel group study was to investigate impact of contact lens wear (CLW) on LIPCOF and secondly the impact of contact lens wear on lid-wiper epitheliopathy (LWE) and dry eye symptoms.

Methods: After a 2-week wash-out phase with a hydrogen peroxide care regimen, 30 experienced contact lens wearers (female: 25, male: 5; median age: 34. Read More

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http://dx.doi.org/10.1016/j.clae.2018.12.005DOI Listing
December 2018
4 Reads

Evaluation of an enhanced viscosity artificial tear for moderate to severe dry eye disease: A multicenter, double-masked, randomized 30-day study.

Cont Lens Anterior Eye 2018 Dec 17. Epub 2018 Dec 17.

Allergan International Medical Affairs, Marlow, Buckinghamshire, UK. Electronic address:

Purpose: In a randomized, controlled clinical trial, two lubricant artificial tear formulations with enhanced viscosity were compared: an investigational product at the time, containing carboxymethylcellulose 1.0% and glycerin 0.9% (CMC-GLY) with osmoprotectants, and a standard formula containing carboxymethylcellulose 1. Read More

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http://dx.doi.org/10.1016/j.clae.2018.12.003DOI Listing
December 2018
6 Reads

Lactoferrin-loaded contact lenses counteract cytotoxicity caused in vitro by keratoconic tears.

Cont Lens Anterior Eye 2018 Dec 11. Epub 2018 Dec 11.

Department of Biotechnology and Biosciences, University of Milano - Bicocca, Piazza della Scienza 2, I-20126, Milan, Italy; Optic and Optometry Center of the University of Milano - Bicocca (COMiB), Italy.

Lactoferrin (LF), an iron-binding protein with antioxidant activity, is significantly reduced in the lacrimal film of patients affected by keratoconus (KC) compared to healthy subjects, and this is supposed to be the cause for tear iron increase and consequent iron deposition and oxygen free radical accumulation in the cornea. We decided to study if LF-loaded contact lenses (LF-CLs) could exert antioxidant activity on epithelial cells incubated in tears collected from two patients affected by keratoconus (KC1 and KC2). Moreover through this model we indirectly estimated iron concentration in the tears of healthy and KC subjects. Read More

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http://dx.doi.org/10.1016/j.clae.2018.12.004DOI Listing
December 2018
1 Read

Tear dynamics under scleral lenses.

Cont Lens Anterior Eye 2019 Feb 10;42(1):43-48. Epub 2018 Dec 10.

Clinical Research Center, School of Optometry, University of California, Berkeley, United States; Vision Science Graduate Program, University of California, Berkeley, United States. Electronic address:

Purpose: To evaluate post-lens tear dynamics at two different time points during scleral lens wear in two cohorts with 10 neophytes each.

Methods: All subjects wore bilaterally scleral lenses for 5 h on 3 separate visits. Post-lens tear exchange was measured using Out-in method, which required 5 μL of 2% FITC-Dextran instilled on the bulbar conjunctiva during lens wear. Read More

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http://dx.doi.org/10.1016/j.clae.2018.11.016DOI Listing
February 2019
2 Reads

Evaluation estrogen, progesteron and androgen receptor expressions in corneal epithelium in keratoconus.

Cont Lens Anterior Eye 2018 Dec 8. Epub 2018 Dec 8.

Hacettepe University, Bioengineering, Ankara, Turkey.

Purpose: To evaluate the role of sex steroid hormone receptors in corneal epithelium in etiopathogenesis of keratoconus (KC).

Methods: Thirty patients with KC who were planned for corneal collagen-crosslinking and 20 patients who were planned for excimer laser for refractive errors included in this study. Corneal epitheliums were curated mechanically during surgeries. Read More

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http://dx.doi.org/10.1016/j.clae.2018.11.015DOI Listing
December 2018
4 Reads

Clinical factors associated with contact lens dropout.

Cont Lens Anterior Eye 2018 Dec 8. Epub 2018 Dec 8.

Centre for Ocular Research and Education (CORE), School of Optometry and Vision Science, University of Waterloo, Waterloo, ON, Canada.

Purpose: Contact lens (CL) dropout is estimated to be approximately equal to the number of new wearers per year, resulting in virtually no growth in the global CL market. The purpose of this study was to determine ocular and CL factors associated with CL dropout.

Methods: This five-site study recruited subjects 18-45 years of age who had ceased CL wear within the past 6-12 months due to discomfort. Read More

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http://dx.doi.org/10.1016/j.clae.2018.12.002DOI Listing
December 2018
6 Reads

Investigating the subjective cooling effect of eyelid cleansing gel on eyelid and ocular surface temperature.

Cont Lens Anterior Eye 2018 Dec 7. Epub 2018 Dec 7.

Ophthalmic Research Group, School of Life & Health Sciences, Aston University, Birmingham, B4 7ET, United Kingdom; Thea Pharmaceuticals Limited, Keele University Science & Innovation Park, Newcastle-Under-Lyme, ST5 5NT, United Kingdom.

Purpose: To investigate if the application of Blephagel, an eyelid cleansing gel, causes subjective and/or objective cooling effects by measuring ocular symptomology and temperature.

Methods: Twenty-five healthy subjects underwent baseline non-invasive temperature measurements on the closed upper eyelid (centrally, nasally, and temporally) and ocular surface temperature (OST) on both eyes using an infrared camera. A standard application of Blephagel was then applied to the closed upper eyelid and eyelashes with a sterile cotton-wool to one eye selected at random. Read More

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http://dx.doi.org/10.1016/j.clae.2018.12.001DOI Listing
December 2018
3 Reads

Corneal structure, transparency, thickness and optical density (densitometry), especially as relevant to contact lens wear-a review.

Cont Lens Anterior Eye 2018 Nov 28. Epub 2018 Nov 28.

Department of Vision Sciences, Glasgow Caledonian University, Cowcaddens Road, Glasgow G4 0BA, United Kingdom. Electronic address:

Clinical instruments using Scheimpflug image-based methods to obtain optical sectional images of the cornea have been introduced in recent years along with proposals that it should be possible to routinely and reliably measure the optical density (referred to as the densitometry) of the human cornea in situ. Such a concept is reviewed from the perspective of what might be considered as the basic principles underlying the understanding of corneal transparency (from the 1950's) and the progressive changes in these ideas from subjective slitlamp-based clinical observations from the late 1960's, especially in contact lens wearers. Much more has been learned about the overall macrostructure (including corneal thickness) and the ultrastructure of the cornea from contemporary studies in the 1990's, and these aspects of the cornea will be reviewed alongside consideration of the methods of assessing the optical characteristics of the cornea in the living eye. Read More

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http://dx.doi.org/10.1016/j.clae.2018.11.014DOI Listing
November 2018
2 Reads

Determination of central corneal clearance in scleral lenses with an optical biometer and agreement with subjective evaluation.

Cont Lens Anterior Eye 2019 Feb 28;42(1):28-35. Epub 2018 Nov 28.

Clinical & Experimental Optometry Research Lab (CEORLab), Center of Physics. University of Minho, Braga, Portugal.

Purpose: To compare three methods to measure central corneal clearance (CCC) during scleral lens wear: subjective (slit lamp), image processed (ImageJ) and with an optic biometer. The optic biometer technique was validated in comparison to an OCT in the first part of the study.

Methods: Twenty-two eyes (11 subjects) with healthy corneas were recruited. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13670484183092
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http://dx.doi.org/10.1016/j.clae.2018.11.013DOI Listing
February 2019
7 Reads

Scleral schism.

Cont Lens Anterior Eye 2019 Feb 1;42(1):1-2. Epub 2018 Dec 1.

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http://dx.doi.org/10.1016/j.clae.2018.11.004DOI Listing
February 2019
2 Reads

Intraocular pressure (IOP) measurements in keratoconic patients: Do variations in IOP respect variations in corneal thickness and corneal curvature?

Cont Lens Anterior Eye 2019 Apr 30;42(2):216-219. Epub 2018 Nov 30.

Belfast Health and Social Care Trust, Northern Ireland, UK. Electronic address:

Purpose: To explore the relationship between intraocular pressure (IOP) measurements and topographical variations in corneal curvature and corneal thickness in a cohort of keratoconic patients presenting to a newly-established regional Keratoconic diagnostic and monitoring clinic in Northern Ireland.

Methods: IOP was recorded, using a hand held ICARE tonometer, at central, nasal and temporal locations on keratoconic corneae of 27 consecutive patients attending clinic. Pachymetry and sagittal keratometry were recorded in matched locations using the Pentacam Topographer. Read More

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http://dx.doi.org/10.1016/j.clae.2018.11.007DOI Listing
April 2019
4 Reads

Effects of a sea buckthorn oil spray emulsion on dry eye.

Cont Lens Anterior Eye 2018 Nov 26. Epub 2018 Nov 26.

Turun Silmäexpertit Ltd, Turku, Finland.

Purpose: To investigate the effects of a sea buckthorn oil and sodium hyaluronate-containing eyelid spray emulsion (SB spray) on dry eye.

Methods: A randomized controlled study was carried out. Adults (25-70 years) with Ocular Surface Disease Index (OSDI) ≥20 and moderate or severe dryness, burning or grittiness of the eyes were included. Read More

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http://dx.doi.org/10.1016/j.clae.2018.11.011DOI Listing
November 2018
6 Reads

Rationale for 24-hour management of dry eye disease: A review.

Authors:
M Guillon S Shah

Cont Lens Anterior Eye 2019 Apr 27;42(2):147-154. Epub 2018 Nov 27.

School of Life and Health Sciences, Aston University, Birmingham, UK; Midland Eye, Solihull, UK; Birmingham and Midland Eye Centre, City Hospital, Birmingham, UK.

The symptom severity of patients with dry eye disease (DED) varies over a 24-hour period. It is typically worse upon waking than later in the morning and deteriorates towards the evening. Substantial differences in the characteristics and physical properties of the tear film, such as levels of inflammation, pH, osmolarity, volume and stability, also exist between night (sleeping) and day (waking), and over the course of the day itself. Read More

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http://dx.doi.org/10.1016/j.clae.2018.11.008DOI Listing
April 2019
3 Reads

The ability of the Contact Lens Dry Eye Questionnaire (CLDEQ)-8 to detect ocular surface alterations in contact lens wearers.

Cont Lens Anterior Eye 2018 Nov 26. Epub 2018 Nov 26.

Institute of Applied Ophthalmobiology (IOBA)-University of Valladolid, Valladolid, Spain; Department of Theoretical Physics, Atomic and Optics, University of Valladolid, Valladolid, Spain; Networking Research Center on Bioengineering Biomaterials and Nanomedicine (CIBER-BBN), Valladolid, Spain. Electronic address:

Purpose: To study whether some ocular surface alterations could be associated with contact lens (CL) wearers suffering from CL discomfort (CLD) detected using the Contact Lens Dry Eye Questionnaire (CLDEQ)-8.

Methods: Forty-one soft CL wearers further classified into symptomatic CL wearers (SCLW) and asymptomatic CL wearers (ACLW) by the CLDEQ-8, and 20 non CL wearers (NCLW) were included. Tear osmolarity, slit-lamp biomicroscopy findings, tear film break-up time, corneal and conjunctival staining, and Schirmer test were performed 24 h after CL removal. Read More

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http://dx.doi.org/10.1016/j.clae.2018.11.012DOI Listing
November 2018
3 Reads

The effect of pregnancy on tear osmolarity.

Cont Lens Anterior Eye 2019 Apr 24;42(2):196-199. Epub 2018 Nov 24.

Ondokuz Mayıs University, Faculty of Medicine, Department of Ophtalmology, Samsun, Turkey.

Objective: To examine the effect of pregnancy on the lacrimal system through tear osmolarity measurement and the Schirmer test.

Material And Method: The study consisted of two groups of 30 women between 20 and 40 years old; the women in the study group were in their first trimester of pregnancy, and the women in the control group were not pregnant and did not have any diseases other than refractive error. Tear osmolarity measurement with the TearLab osmolarity system and tear function test Schirmer 1 were carried out on one, randomly chosen eye of each participant. Read More

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http://dx.doi.org/10.1016/j.clae.2018.10.007DOI Listing
April 2019
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Adjunctive effect of orthokeratology and low dose atropine on axial elongation in fast-progressing myopic children-A preliminary retrospective study.

Cont Lens Anterior Eye 2018 Nov 24. Epub 2018 Nov 24.

Department of Ophthalmology and Vision Science, Eye and ENT Hospital, Fudan University, Shanghai, China; NHC Key Laboratory of Myopia (Fudan University), Shanghai, China; Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China. Electronic address:

Purpose: To investigate the adjunctive effect of orthokeratology (ortho-k) and low-dose atropine eye drops on axial length elongation in fast-progressing myopic children.

Methods: Axial elongation in 60 eyes of 60 subjects who completed two years of ortho-k treatment was retrospectively reviewed. They were aged between 5. Read More

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http://dx.doi.org/10.1016/j.clae.2018.10.026DOI Listing
November 2018
2 Reads

Pellucid marginal degeneration: Detection, discrimination from other corneal ectatic disorders and progression.

Cont Lens Anterior Eye 2018 Nov 22. Epub 2018 Nov 22.

Group of Optics and Visual Perception. Department of Optics, Pharmacology and Anatomy, University of Alicante, Spain. Electronic address:

Pellucid marginal degeneration (PMD) is a non-inflammatory ectatic corneal disease characterized by a narrow band of corneal thinning separated from the limbus by a relatively uninvolved area 1-2 mm in width. It is a rare corneal disorder that shares many clinical characteristics with other corneal ectasias, such as keratoconus, keratoglobus or Terrien marginal degeneration. PMD usually starts later in life than keratoconus and progresses slower than keratoconus. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13670484183094
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http://dx.doi.org/10.1016/j.clae.2018.11.010DOI Listing
November 2018
11 Reads

Screening utility of a rapid non-invasive dry eye assessment algorithm.

Cont Lens Anterior Eye 2018 Nov 22. Epub 2018 Nov 22.

Department of Ophthalmology, New Zealand National Eye Centre, The University of Auckland, New Zealand. Electronic address:

Purpose: To evaluate the discriminative ability of a rapid non-invasive dry eye assessment algorithm (global evaluation component: SANDE questionnaire, and non-invasive tear film breakup time; subtype classification testing component: tear film lipid layer grade, and tear meniscus height) in detecting dry eye disease, as defined by the TFOS DEWS II diagnostic criteria.

Methods: Two hundred and thirty-five participants (77 male, 158 female), with a mean ± SD age of 43 ± 17 years, were recruited into a prospective diagnostic accuracy study. OSDI, DEQ-5, and SANDE dry eye symptomology scores; non-invasive tear film breakup time; absolute and inter-ocular differences in tear osmolarity; corneal, conjunctival, and lid margin staining scores; tear film lipid layer, meibum expressibility, meibomian gland orifice plugging, and eyelid margin telangiectasia grades; and tear meniscus height were evaluated in a single clinical session. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13670484183096
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http://dx.doi.org/10.1016/j.clae.2018.11.009DOI Listing
November 2018
20 Reads

Vision stolen by a hidden thief: 5-Year retention of a bandage contact lens.

Cont Lens Anterior Eye 2019 Apr 18;42(2):229-231. Epub 2018 Nov 18.

Dept. of Ophthalmology, Peking University third Hospital, Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, No. 49, North Garden Road, Haidian District, 100191, Beijing, China. Electronic address:

An 80 year-old male patient was prescribed a bandage contact lens on the left eye 5 years ago because of an injury on the eye by a wooden stick. He was never followed up to remove the contact lens. Two years ago, he suffered from gradually decreased visual acuity in the left eye. Read More

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http://dx.doi.org/10.1016/j.clae.2018.10.017DOI Listing
April 2019
17 Reads

UV damage of the anterior ocular surface - microstructural evidence by in vivo confocal microscopy.

Cont Lens Anterior Eye 2018 12 28;41(6):482-488. Epub 2018 Jun 28.

Department of Ophthalmology and Visual Science, Medical University, 55 Marin Drinov Str., Varna, 9002, Bulgaria. Electronic address:

Purpose: To evaluate and describe the microstructural changes at the ocular surface in response to habitual ocular sun exposure, correlate them with the UV protection habits and follow their dynamics using in vivo confocal microscopy(ICM).

Methods: For a period of minimum 4 months 200 subjects (400 eyes), aged 28 ± 7.3 years, were recruited with the agreement that they will spend their summer exclusively in the region of the Black Sea coast at 43 °N latitude and will be examined before and after the summer. Read More

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http://dx.doi.org/10.1016/j.clae.2018.06.004DOI Listing
December 2018
14 Reads

Assessment of a practitioner's perception of scleral contact lens complications.

Cont Lens Anterior Eye 2019 Feb 17;42(1):15-19. Epub 2018 Nov 17.

University of Houston, College of Optometry, United States.

Purpose: The purpose of this survey was to better understand scleral lens (SL) practitioners' fitting preferences and minor SL complications and their subsequent treatments.

Method: Practitioners who attended the 2017 Global Specialty Lens Symposium were asked to complete an electronic questionnaire that was created by the investigators, a survey that asked practitioners about their SL fitting experience and preferences, their patients' experience with poor SL wetting, SL fogging, ocular symptoms (redness, pain/discomfort, dryness), and blurred central and side vision, and how the practitioners treated these conditions.

Results: This study analyzed data from 164 SL practitioners. Read More

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http://dx.doi.org/10.1016/j.clae.2018.11.003DOI Listing
February 2019
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A measure of tear inflow in habitual scleral lens wearers with and without midday fogging.

Cont Lens Anterior Eye 2019 Feb 16;42(1):36-42. Epub 2018 Nov 16.

University of the Incarnate Word, Rosenberg School of Optometry, San Antonio, TX, United States.

Purpose: The purpose of this pilot study was to evaluate tear inflow in a scleral lens system using fluorophotometry, and indirectly assess the exchange of the tear reservoir in habitual scleral lens wearers with the presence or absence of midday fogging (MDF).

Methods: Habitual scleral lens wearers (n=23) and normal scleral lens neophytes (n=10) were recruited. Of the 23 habitual wearers, 11 of them experienced MDF and 12 did not have a diagnosis of MDF. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13670484183051
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http://dx.doi.org/10.1016/j.clae.2018.10.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340712PMC
February 2019
14 Reads