1,114 results match your criteria Contact Lens and Anterior Eye[Journal]


Pentacam and vector analysis to evaluate longitudinal corneal tomographical changes in non-progressive keratoconus eyes.

Cont Lens Anterior Eye 2019 Feb 13. Epub 2019 Feb 13.

Department of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, Baronissi, SA, Italy.

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http://dx.doi.org/10.1016/j.clae.2019.02.002DOI Listing
February 2019

Rigid gas permeable contact lenses for visual rehabilitation of unilateral aphakic children in China.

Cont Lens Anterior Eye 2018 Dec 28. Epub 2018 Dec 28.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China. Electronic address:

Purpose: To investigate the effectiveness, safety and tolerance of rigid gas-permeable contact lenses (RGP CLs) in the visual rehabilitation of unilateral aphakic children in China.

Methods: Records of 36 children (36 eyes) with RGP CLs to unilateral aphakia between 2014 and 2018 were evaluated. Each enrolled child underwent vision assessment (visual acuity, fixation, and deviation) at each follow-up visit and their caregivers completed a questionnaire designed to find out the reasons for RGP CLs dropout. Read More

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http://dx.doi.org/10.1016/j.clae.2018.12.009DOI Listing
December 2018
1 Read

A novel method in correcting aberropia using pin hole soft contact lenses: A case report.

Cont Lens Anterior Eye 2018 Dec 26. Epub 2018 Dec 26.

Ahalia School of Optometry, Ahalia Foundation Eye Hospital, Palakkad 678557, India. Electronic address:

Aberropia leads to decrease in image quality due to higher order aberrations (HOA). Correction of these HOA poses a great challenge to clinicians. A case report is presented here where a 30 year old male visited with complaints of cloudy vision, diplopia in reduced illumination along with inferior vertical elongation of light during night time in the right eye since 6 years. Read More

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http://dx.doi.org/10.1016/j.clae.2018.12.007DOI Listing
December 2018
1 Read

Randomized crossover trial of silicone hydrogel contact lenses.

Cont Lens Anterior Eye 2018 Dec 23. Epub 2018 Dec 23.

Department of Optometry and Vision, Faculty of Optics and Optometry, Complutense University of Madrid, Madrid, Spain.

Purpose: The aim of the current study is to assess, using new technologies, the interaction of four monthly silicone hydrogel contact lenses on the ocular surface and the comfort over 15 days of use.

Methods: Prospective cross-over, randomized and double-masked study including four materials (lotrafilcon-B, samfilcon-A , comfilcon-A and filcom-V3). Clinical examination was performed in the following order: tear meniscus height, first break-up of the tear film, the average time of all tear film breakup incidents, bulbar redness, limbal redness (Keratograph 5M ,Oculus, Germany); central corneal thickness (Pentacam, Oculus, Germany), thermography values (FLIR A325; FLIR Systems Inc. Read More

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http://dx.doi.org/10.1016/j.clae.2018.12.006DOI Listing
December 2018
3 Reads

Impact of soft contact lenses on lid- parallel conjunctival folds.

Cont Lens Anterior Eye 2018 Dec 18. Epub 2018 Dec 18.

Dr. Heiko Pult - Optometry and Vision Research, Weinheim, Germany.

Purpose: Lid-parallel conjunctival folds (LIPCOF) are related to dry eye symptoms and appear to be related to mechanical forces in blinks. The primary aim of this longitudinal, parallel group study was to investigate impact of contact lens wear (CLW) on LIPCOF and secondly the impact of contact lens wear on lid-wiper epitheliopathy (LWE) and dry eye symptoms.

Methods: After a 2-week wash-out phase with a hydrogen peroxide care regimen, 30 experienced contact lens wearers (female: 25, male: 5; median age: 34. Read More

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http://dx.doi.org/10.1016/j.clae.2018.12.005DOI Listing
December 2018
3 Reads

Evaluation of an enhanced viscosity artificial tear for moderate to severe dry eye disease: A multicenter, double-masked, randomized 30-day study.

Cont Lens Anterior Eye 2018 Dec 17. Epub 2018 Dec 17.

Allergan International Medical Affairs, Marlow, Buckinghamshire, UK. Electronic address:

Purpose: In a randomized, controlled clinical trial, two lubricant artificial tear formulations with enhanced viscosity were compared: an investigational product at the time, containing carboxymethylcellulose 1.0% and glycerin 0.9% (CMC-GLY) with osmoprotectants, and a standard formula containing carboxymethylcellulose 1. Read More

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http://dx.doi.org/10.1016/j.clae.2018.12.003DOI Listing
December 2018
2 Reads

Lactoferrin-loaded contact lenses counteract cytotoxicity caused in vitro by keratoconic tears.

Cont Lens Anterior Eye 2018 Dec 11. Epub 2018 Dec 11.

Department of Biotechnology and Biosciences, University of Milano - Bicocca, Piazza della Scienza 2, I-20126, Milan, Italy; Optic and Optometry Center of the University of Milano - Bicocca (COMiB), Italy.

Lactoferrin (LF), an iron-binding protein with antioxidant activity, is significantly reduced in the lacrimal film of patients affected by keratoconus (KC) compared to healthy subjects, and this is supposed to be the cause for tear iron increase and consequent iron deposition and oxygen free radical accumulation in the cornea. We decided to study if LF-loaded contact lenses (LF-CLs) could exert antioxidant activity on epithelial cells incubated in tears collected from two patients affected by keratoconus (KC1 and KC2). Moreover through this model we indirectly estimated iron concentration in the tears of healthy and KC subjects. Read More

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http://dx.doi.org/10.1016/j.clae.2018.12.004DOI Listing
December 2018
1 Read

Tear dynamics under scleral lenses.

Cont Lens Anterior Eye 2019 Feb 10;42(1):43-48. Epub 2018 Dec 10.

Clinical Research Center, School of Optometry, University of California, Berkeley, United States; Vision Science Graduate Program, University of California, Berkeley, United States. Electronic address:

Purpose: To evaluate post-lens tear dynamics at two different time points during scleral lens wear in two cohorts with 10 neophytes each.

Methods: All subjects wore bilaterally scleral lenses for 5 h on 3 separate visits. Post-lens tear exchange was measured using Out-in method, which required 5 μL of 2% FITC-Dextran instilled on the bulbar conjunctiva during lens wear. Read More

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http://dx.doi.org/10.1016/j.clae.2018.11.016DOI Listing
February 2019
1 Read

Evaluation estrogen, progesteron and androgen receptor expressions in corneal epithelium in keratoconus.

Cont Lens Anterior Eye 2018 Dec 8. Epub 2018 Dec 8.

Hacettepe University, Bioengineering, Ankara, Turkey.

Purpose: To evaluate the role of sex steroid hormone receptors in corneal epithelium in etiopathogenesis of keratoconus (KC).

Methods: Thirty patients with KC who were planned for corneal collagen-crosslinking and 20 patients who were planned for excimer laser for refractive errors included in this study. Corneal epitheliums were curated mechanically during surgeries. Read More

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http://dx.doi.org/10.1016/j.clae.2018.11.015DOI Listing
December 2018
3 Reads

Clinical factors associated with contact lens dropout.

Cont Lens Anterior Eye 2018 Dec 8. Epub 2018 Dec 8.

Centre for Ocular Research and Education (CORE), School of Optometry and Vision Science, University of Waterloo, Waterloo, ON, Canada.

Purpose: Contact lens (CL) dropout is estimated to be approximately equal to the number of new wearers per year, resulting in virtually no growth in the global CL market. The purpose of this study was to determine ocular and CL factors associated with CL dropout.

Methods: This five-site study recruited subjects 18-45 years of age who had ceased CL wear within the past 6-12 months due to discomfort. Read More

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http://dx.doi.org/10.1016/j.clae.2018.12.002DOI Listing
December 2018
5 Reads

Investigating the subjective cooling effect of eyelid cleansing gel on eyelid and ocular surface temperature.

Cont Lens Anterior Eye 2018 Dec 7. Epub 2018 Dec 7.

Ophthalmic Research Group, School of Life & Health Sciences, Aston University, Birmingham, B4 7ET, United Kingdom; Thea Pharmaceuticals Limited, Keele University Science & Innovation Park, Newcastle-Under-Lyme, ST5 5NT, United Kingdom.

Purpose: To investigate if the application of Blephagel, an eyelid cleansing gel, causes subjective and/or objective cooling effects by measuring ocular symptomology and temperature.

Methods: Twenty-five healthy subjects underwent baseline non-invasive temperature measurements on the closed upper eyelid (centrally, nasally, and temporally) and ocular surface temperature (OST) on both eyes using an infrared camera. A standard application of Blephagel was then applied to the closed upper eyelid and eyelashes with a sterile cotton-wool to one eye selected at random. Read More

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http://dx.doi.org/10.1016/j.clae.2018.12.001DOI Listing
December 2018
2 Reads

Corneal structure, transparency, thickness and optical density (densitometry), especially as relevant to contact lens wear-a review.

Cont Lens Anterior Eye 2018 Nov 28. Epub 2018 Nov 28.

Department of Vision Sciences, Glasgow Caledonian University, Cowcaddens Road, Glasgow G4 0BA, United Kingdom. Electronic address:

Clinical instruments using Scheimpflug image-based methods to obtain optical sectional images of the cornea have been introduced in recent years along with proposals that it should be possible to routinely and reliably measure the optical density (referred to as the densitometry) of the human cornea in situ. Such a concept is reviewed from the perspective of what might be considered as the basic principles underlying the understanding of corneal transparency (from the 1950's) and the progressive changes in these ideas from subjective slitlamp-based clinical observations from the late 1960's, especially in contact lens wearers. Much more has been learned about the overall macrostructure (including corneal thickness) and the ultrastructure of the cornea from contemporary studies in the 1990's, and these aspects of the cornea will be reviewed alongside consideration of the methods of assessing the optical characteristics of the cornea in the living eye. Read More

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http://dx.doi.org/10.1016/j.clae.2018.11.014DOI Listing
November 2018
1 Read

Determination of central corneal clearance in scleral lenses with an optical biometer and agreement with subjective evaluation.

Cont Lens Anterior Eye 2019 Feb 28;42(1):28-35. Epub 2018 Nov 28.

Clinical & Experimental Optometry Research Lab (CEORLab), Center of Physics. University of Minho, Braga, Portugal.

Purpose: To compare three methods to measure central corneal clearance (CCC) during scleral lens wear: subjective (slit lamp), image processed (ImageJ) and with an optic biometer. The optic biometer technique was validated in comparison to an OCT in the first part of the study.

Methods: Twenty-two eyes (11 subjects) with healthy corneas were recruited. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13670484183092
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http://dx.doi.org/10.1016/j.clae.2018.11.013DOI Listing
February 2019
6 Reads

Scleral schism.

Cont Lens Anterior Eye 2019 Feb 1;42(1):1-2. Epub 2018 Dec 1.

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http://dx.doi.org/10.1016/j.clae.2018.11.004DOI Listing
February 2019
2 Reads

Intraocular pressure (IOP) measurements in keratoconic patients: Do variations in IOP respect variations in corneal thickness and corneal curvature?

Cont Lens Anterior Eye 2018 Nov 30. Epub 2018 Nov 30.

Belfast Health and Social Care Trust, Northern Ireland, UK. Electronic address:

Purpose: To explore the relationship between intraocular pressure (IOP) measurements and topographical variations in corneal curvature and corneal thickness in a cohort of keratoconic patients presenting to a newly-established regional Keratoconic diagnostic and monitoring clinic in Northern Ireland.

Methods: IOP was recorded, using a hand held ICARE tonometer, at central, nasal and temporal locations on keratoconic corneae of 27 consecutive patients attending clinic. Pachymetry and sagittal keratometry were recorded in matched locations using the Pentacam Topographer. Read More

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http://dx.doi.org/10.1016/j.clae.2018.11.007DOI Listing
November 2018
3 Reads

Effects of a sea buckthorn oil spray emulsion on dry eye.

Cont Lens Anterior Eye 2018 Nov 26. Epub 2018 Nov 26.

Turun Silmäexpertit Ltd, Turku, Finland.

Purpose: To investigate the effects of a sea buckthorn oil and sodium hyaluronate-containing eyelid spray emulsion (SB spray) on dry eye.

Methods: A randomized controlled study was carried out. Adults (25-70 years) with Ocular Surface Disease Index (OSDI) ≥20 and moderate or severe dryness, burning or grittiness of the eyes were included. Read More

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http://dx.doi.org/10.1016/j.clae.2018.11.011DOI Listing
November 2018
2 Reads

Rationale for 24-hour management of dry eye disease: A review.

Authors:
M Guillon S Shah

Cont Lens Anterior Eye 2018 Nov 26. Epub 2018 Nov 26.

School of Life and Health Sciences, Aston University, Birmingham, UK; Midland Eye, Solihull, UK; Birmingham and Midland Eye Centre, City Hospital, Birmingham, UK.

The symptom severity of patients with dry eye disease (DED) varies over a 24-hour period. It is typically worse upon waking than later in the morning and deteriorates towards the evening. Substantial differences in the characteristics and physical properties of the tear film, such as levels of inflammation, pH, osmolarity, volume and stability, also exist between night (sleeping) and day (waking), and over the course of the day itself. Read More

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http://dx.doi.org/10.1016/j.clae.2018.11.008DOI Listing
November 2018
2 Reads

The ability of the Contact Lens Dry Eye Questionnaire (CLDEQ)-8 to detect ocular surface alterations in contact lens wearers.

Cont Lens Anterior Eye 2018 Nov 26. Epub 2018 Nov 26.

Institute of Applied Ophthalmobiology (IOBA)-University of Valladolid, Valladolid, Spain; Department of Theoretical Physics, Atomic and Optics, University of Valladolid, Valladolid, Spain; Networking Research Center on Bioengineering Biomaterials and Nanomedicine (CIBER-BBN), Valladolid, Spain. Electronic address:

Purpose: To study whether some ocular surface alterations could be associated with contact lens (CL) wearers suffering from CL discomfort (CLD) detected using the Contact Lens Dry Eye Questionnaire (CLDEQ)-8.

Methods: Forty-one soft CL wearers further classified into symptomatic CL wearers (SCLW) and asymptomatic CL wearers (ACLW) by the CLDEQ-8, and 20 non CL wearers (NCLW) were included. Tear osmolarity, slit-lamp biomicroscopy findings, tear film break-up time, corneal and conjunctival staining, and Schirmer test were performed 24 h after CL removal. Read More

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http://dx.doi.org/10.1016/j.clae.2018.11.012DOI Listing
November 2018
1 Read

The effect of pregnancy on tear osmolarity.

Cont Lens Anterior Eye 2018 Nov 24. Epub 2018 Nov 24.

Ondokuz Mayıs University, Faculty of Medicine, Department of Ophtalmology, Samsun, Turkey.

Objective: To examine the effect of pregnancy on the lacrimal system through tear osmolarity measurement and the Schirmer test.

Material And Method: The study consisted of two groups of 30 women between 20 and 40 years old; the women in the study group were in their first trimester of pregnancy, and the women in the control group were not pregnant and did not have any diseases other than refractive error. Tear osmolarity measurement with the TearLab osmolarity system and tear function test Schirmer 1 were carried out on one, randomly chosen eye of each participant. Read More

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http://dx.doi.org/10.1016/j.clae.2018.10.007DOI Listing
November 2018
1 Read

Adjunctive effect of orthokeratology and low dose atropine on axial elongation in fast-progressing myopic children-A preliminary retrospective study.

Cont Lens Anterior Eye 2018 Nov 24. Epub 2018 Nov 24.

Department of Ophthalmology and Vision Science, Eye and ENT Hospital, Fudan University, Shanghai, China; NHC Key Laboratory of Myopia (Fudan University), Shanghai, China; Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China. Electronic address:

Purpose: To investigate the adjunctive effect of orthokeratology (ortho-k) and low-dose atropine eye drops on axial length elongation in fast-progressing myopic children.

Methods: Axial elongation in 60 eyes of 60 subjects who completed two years of ortho-k treatment was retrospectively reviewed. They were aged between 5. Read More

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http://dx.doi.org/10.1016/j.clae.2018.10.026DOI Listing
November 2018
1 Read

Pellucid marginal degeneration: Detection, discrimination from other corneal ectatic disorders and progression.

Cont Lens Anterior Eye 2018 Nov 22. Epub 2018 Nov 22.

Group of Optics and Visual Perception. Department of Optics, Pharmacology and Anatomy, University of Alicante, Spain. Electronic address:

Pellucid marginal degeneration (PMD) is a non-inflammatory ectatic corneal disease characterized by a narrow band of corneal thinning separated from the limbus by a relatively uninvolved area 1-2 mm in width. It is a rare corneal disorder that shares many clinical characteristics with other corneal ectasias, such as keratoconus, keratoglobus or Terrien marginal degeneration. PMD usually starts later in life than keratoconus and progresses slower than keratoconus. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13670484183094
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http://dx.doi.org/10.1016/j.clae.2018.11.010DOI Listing
November 2018
9 Reads

Screening utility of a rapid non-invasive dry eye assessment algorithm.

Cont Lens Anterior Eye 2018 Nov 22. Epub 2018 Nov 22.

Department of Ophthalmology, New Zealand National Eye Centre, The University of Auckland, New Zealand. Electronic address:

Purpose: To evaluate the discriminative ability of a rapid non-invasive dry eye assessment algorithm (global evaluation component: SANDE questionnaire, and non-invasive tear film breakup time; subtype classification testing component: tear film lipid layer grade, and tear meniscus height) in detecting dry eye disease, as defined by the TFOS DEWS II diagnostic criteria.

Methods: Two hundred and thirty-five participants (77 male, 158 female), with a mean ± SD age of 43 ± 17 years, were recruited into a prospective diagnostic accuracy study. OSDI, DEQ-5, and SANDE dry eye symptomology scores; non-invasive tear film breakup time; absolute and inter-ocular differences in tear osmolarity; corneal, conjunctival, and lid margin staining scores; tear film lipid layer, meibum expressibility, meibomian gland orifice plugging, and eyelid margin telangiectasia grades; and tear meniscus height were evaluated in a single clinical session. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13670484183096
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http://dx.doi.org/10.1016/j.clae.2018.11.009DOI Listing
November 2018
15 Reads

Vision stolen by a hidden thief: 5-Year retention of a bandage contact lens.

Cont Lens Anterior Eye 2018 Nov 18. Epub 2018 Nov 18.

Dept. of Ophthalmology, Peking University third Hospital, Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, No. 49, North Garden Road, Haidian District, 100191, Beijing, China. Electronic address:

An 80 year-old male patient was prescribed a bandage contact lens on the left eye 5 years ago because of an injury on the eye by a wooden stick. He was never followed up to remove the contact lens. Two years ago, he suffered from gradually decreased visual acuity in the left eye. Read More

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http://dx.doi.org/10.1016/j.clae.2018.10.017DOI Listing
November 2018
9 Reads

UV damage of the anterior ocular surface - microstructural evidence by in vivo confocal microscopy.

Cont Lens Anterior Eye 2018 Dec 28;41(6):482-488. Epub 2018 Jun 28.

Department of Ophthalmology and Visual Science, Medical University, 55 Marin Drinov Str., Varna, 9002, Bulgaria. Electronic address:

Purpose: To evaluate and describe the microstructural changes at the ocular surface in response to habitual ocular sun exposure, correlate them with the UV protection habits and follow their dynamics using in vivo confocal microscopy(ICM).

Methods: For a period of minimum 4 months 200 subjects (400 eyes), aged 28 ± 7.3 years, were recruited with the agreement that they will spend their summer exclusively in the region of the Black Sea coast at 43 °N latitude and will be examined before and after the summer. Read More

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http://dx.doi.org/10.1016/j.clae.2018.06.004DOI Listing
December 2018
11 Reads

Assessment of a practitioner's perception of scleral contact lens complications.

Cont Lens Anterior Eye 2019 Feb 17;42(1):15-19. Epub 2018 Nov 17.

University of Houston, College of Optometry, United States.

Purpose: The purpose of this survey was to better understand scleral lens (SL) practitioners' fitting preferences and minor SL complications and their subsequent treatments.

Method: Practitioners who attended the 2017 Global Specialty Lens Symposium were asked to complete an electronic questionnaire that was created by the investigators, a survey that asked practitioners about their SL fitting experience and preferences, their patients' experience with poor SL wetting, SL fogging, ocular symptoms (redness, pain/discomfort, dryness), and blurred central and side vision, and how the practitioners treated these conditions.

Results: This study analyzed data from 164 SL practitioners. Read More

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http://dx.doi.org/10.1016/j.clae.2018.11.003DOI Listing
February 2019
11 Reads

A measure of tear inflow in habitual scleral lens wearers with and without midday fogging.

Cont Lens Anterior Eye 2019 Feb 16;42(1):36-42. Epub 2018 Nov 16.

University of the Incarnate Word, Rosenberg School of Optometry, San Antonio, TX, United States.

Purpose: The purpose of this pilot study was to evaluate tear inflow in a scleral lens system using fluorophotometry, and indirectly assess the exchange of the tear reservoir in habitual scleral lens wearers with the presence or absence of midday fogging (MDF).

Methods: Habitual scleral lens wearers (n=23) and normal scleral lens neophytes (n=10) were recruited. Of the 23 habitual wearers, 11 of them experienced MDF and 12 did not have a diagnosis of MDF. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13670484183051
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http://dx.doi.org/10.1016/j.clae.2018.10.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340712PMC
February 2019
9 Reads

Light disturbance analysis in the controlled randomized clinical trial MiSight Assessment Study Spain (MASS).

Cont Lens Anterior Eye 2018 Nov 15. Epub 2018 Nov 15.

Doctoral and Research School, European University of Madrid, Spain.

Purpose: To evaluate the perception of light disturbances (LD) in children wearing Dual Focus (DF) MiSight® contact lenses (CLs) for myopia control compared with children wearing single vision spectacles (SV).

Methods: This was a randomized, controlled clinical trial involving subjects aged 8-12 with myopia of -0.75 to -4. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13670484183038
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http://dx.doi.org/10.1016/j.clae.2018.11.006DOI Listing
November 2018
8 Reads

Factors influencing pupil behaviour during femtosecond laser assisted cataract surgery.

Cont Lens Anterior Eye 2018 Nov 14. Epub 2018 Nov 14.

University Hospital of Wales, UK; Princess of Wales Hospital, UK.

Aim: Femtosecond laser assisted cataract surgery is associated with pupillary constriction. This study aims to look at patient and surgical factors predisposing to abnormal pupil behaviour during FLACS.

Methods: This prospective observational study included all patients undergoing FLACS in the Princess of Wales Hospital, Bridgend, UK between February and June 2017. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13670484183082
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http://dx.doi.org/10.1016/j.clae.2018.10.010DOI Listing
November 2018
28 Reads

International survey of orthokeratology contact lens fitting.

Cont Lens Anterior Eye 2018 Nov 15. Epub 2018 Nov 15.

Menicon Co., Ltd., Nagoya, Japan.

Purpose: . To determine the extent of orthokeratology (OK) contact lens fitting worldwide and to characterize associated demographics and fitting patterns.

Methods: . Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13670484183093
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http://dx.doi.org/10.1016/j.clae.2018.11.005DOI Listing
November 2018
13 Reads

A review of international medical device regulations: Contact lenses and lens care solutions.

Cont Lens Anterior Eye 2018 Nov 13. Epub 2018 Nov 13.

Ocupharm Diagnostic Group Research, Faculty of Optic and Optometry, Universidad Complutense de Madrid, Madrid, Spain; Department of Optics II (Optometry and Vision), Faculty of Optic and Optometry, Universidad Complutense de Madrid, Madrid, Spain. Electronic address:

Medical devices are under strict regulatory oversight worldwide and such regulations prioritise patient safety and efficacy over anything else. Contact lenses fall under the medical device category - a result of direct contact with the eye. Equally regulated are the contact lens care product solutions, which include cleaning and maintenance solutions and lubricating and rewetting drops. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13670484183079
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http://dx.doi.org/10.1016/j.clae.2018.11.001DOI Listing
November 2018
12 Reads

The treatment of ocular hypotony after trabeculectomy with a scleral lens: A case series.

Cont Lens Anterior Eye 2019 Feb 12;42(1):123-126. Epub 2018 Nov 12.

Visser Contact Lens Practice, Sint Annastraat 93, 6524 EJ Nijmegen, the Netherlands. Electronic address:

Purpose: Ocular hypotony after trabeculectomy may be treated medically, surgically and with a tamponade. Three cases are reported in which a scleral lens was applied to treat ocular hypotony after mitomycin C (MMC) augmented trabeculectomy.

Methods: In this retrospective case series the records of three eyes of three patients who developed ocular hypotony after they had undergone trabeculectomy augmented with MMC were evaluated. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13670484183085
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http://dx.doi.org/10.1016/j.clae.2018.10.018DOI Listing
February 2019
13 Reads

Novel in vitro method to determine pre-lens tear break-up time of hydrogel and silicone hydrogel contact lenses.

Cont Lens Anterior Eye 2018 Nov 12. Epub 2018 Nov 12.

Centre for Ocular Research & Education (CORE, formerly CCLR), School of Optometry and Vision Science, 200 University Avenue West, Waterloo, ON, N2L 3G1, Canada.

Purpose: To develop an in vitro model to determine pre-lens non-invasive break-up time (NIBUT) and to subsequently use this method to compare the NIBUT over contemporary daily disposable (DD) contact lenses (CL).

Methods: Three silicone hydrogel (SH) and two conventional hydrogel (CH) DD CLs were incubated in an artificial tear solution (ATS). A model blink cell (MBC) was utilised to mimic intermittent air exposure. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13670484183005
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http://dx.doi.org/10.1016/j.clae.2018.11.002DOI Listing
November 2018
7 Reads

Lid-parallel conjunctival fold (LIPCOF) morphology imaged by optical coherence tomography and its relationship to LIPCOF grade.

Cont Lens Anterior Eye 2018 Nov 12. Epub 2018 Nov 12.

Ophthalmic Research Group, Life and Health Sciences, Aston University, Birmingham, UK; School of Optometry and Vision Sciences, Cardiff University, Cardiff, UK; Optometry and Vision Research, Weinheim, Germany.

Purpose: Lid-parallel conjunctival folds (LIPCOF) are a well-accepted clinical sign in dry eye diagnosis. Commonly, LIPCOF is classified by grading the number of folds observed by slit-lamp microscope. This study investigated the relationship between subjective grading scale and LIPCOF morphology imaged by optical coherence tomography (OCT). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13670484183085
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http://dx.doi.org/10.1016/j.clae.2018.10.025DOI Listing
November 2018
11 Reads

Patients' and prescribers' perception of contact lenses as a potential ocular drug delivery system.

Cont Lens Anterior Eye 2018 Nov 13. Epub 2018 Nov 13.

Drug Discovery, Delivery and Patient Care (DDDPC) Theme, School of Life Sciences, Pharmacy and Chemistry, Department of Pharmacy, Kingston University London, Penrhyn Road, Kingston upon Thames, Surrey, KT1 2EE, United Kingdom. Electronic address:

Contact lenses (CLs) designed to deliver medication gradually to the eye are being developed and investigated for the use in ocular drug delivery. The aim of the current research is to determine patients' acceptance of the use of lenses for ocular drug delivery. In addition, the study aimed to seek the views and perceptions of healthcare professionals (HCPs) on CLs as a method of ocular drug delivery and whether it will be prescribed to treat ocular conditions. Read More

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http://dx.doi.org/10.1016/j.clae.2018.10.023DOI Listing
November 2018
19 Reads

Profile, knowledge, and attitude of contact lens users regarding contact lens wear in Ghana.

Cont Lens Anterior Eye 2018 Nov 8. Epub 2018 Nov 8.

Dashen Opticians, North Ridge Branch, Accra, Ghana.

Background: Contact lenses are gaining popularity in developing countries as an alternative to spectacles for the correction of refractive errors. It is needful, therefore, to generate information to guide the mode of practice, and assist the industry in developing products for the increasing contact-lenses-user population. The purpose of this study was to identify the demographic profile, as well as the knowledge, attitude to wear and care regimen of wearers of contact lenses in Ghana. Read More

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http://dx.doi.org/10.1016/j.clae.2018.10.012DOI Listing
November 2018
75 Reads
2.000 Impact Factor

Therapeutic contact lens fitting in a large tertiary referral centre.

Cont Lens Anterior Eye 2018 Dec 9;41(6):471-472. Epub 2018 Nov 9.

Birmingham and Midland Eye Centre, SWBH, Birmingham, UK.

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http://dx.doi.org/10.1016/j.clae.2018.10.019DOI Listing
December 2018
16 Reads

Longitudinal corneal tomographical changes in eyes of patients with unilateral and bilateral non-progressive keratoconus.

Cont Lens Anterior Eye 2018 Nov 7. Epub 2018 Nov 7.

Ulucanlar Eye Training and Research Hospital, Department of Ophthalmology, Ankara, Turkey.

Aim: To evaluate the tomographic indices changes in keratoconic eyes which were classified as unilateral and bilateral non-progressive keratoconus according to the definition of Global Consensus on keratoconus and ectatic disease.

Methods: Fifty non-progressive fellow eyes of 50 keratoconus patients who underwent corneal cross-linking treatment for the other progressive eyes (group 1), 50 eyes of 50 keratoconus patients who were followed up as bilateral non-progressive keratoconus (group 2), and 50 eyes of 50 control subjects (group 3) were included in this retrospective study. Topographic, topometric, and Belin-Ambrósio Enhanced Ectasia Display-III indices were recorded at baseline and after six months. Read More

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http://dx.doi.org/10.1016/j.clae.2018.10.027DOI Listing
November 2018
7 Reads

Comparison of meibomian gland dropout using two infrared imaging devices.

Cont Lens Anterior Eye 2018 Nov 7. Epub 2018 Nov 7.

Centre for Ocular Research & Education, School of Optometry and Vision Science, University of Waterloo, 200 University Avenue West, Waterloo, N2L 3G1, Canada; School of Optometry and Vision Science, University of Waterloo, 200 University Avenue West, Waterloo, N2L 3G1, Canada. Electronic address:

Purpose: To measure the degree of meibomian gland (MG) dropout in the lower eyelid determined by analysis of images obtained from the LipiView II (LVII) and the Keratograph 5M (K5M).

Methods: The inferior eyelid of each participant was imaged in a random order using both devices. All images were subjectively assessed by a single-masked investigator to determine the extent of MG loss using the Arita 4-point meiboscore grading scale. Read More

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http://dx.doi.org/10.1016/j.clae.2018.10.014DOI Listing
November 2018
6 Reads
2.000 Impact Factor

Hand hygiene is linked to microbial keratitis and corneal inflammatory events.

Cont Lens Anterior Eye 2018 Nov 7. Epub 2018 Nov 7.

Centre for Ocular Research and Education, School of Optometry & Vision Science, University of Waterloo, Waterloo, Ontario, Canada. Electronic address:

Lack of or inadequate hand washing is a risk factor in the development of contact lens related microbial keratitis and corneal inflammatory events. In the public health domain there is compelling evidence that proper hand washing with soap can save lives. The purpose of this review is to draw attention to some of the public health literature in support of hand washing and how education can influence patients' hand hygiene behavior. Read More

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http://dx.doi.org/10.1016/j.clae.2018.10.022DOI Listing
November 2018
12 Reads

Density of crystalline lens and cornea in different trimesters of pregnancy.

Cont Lens Anterior Eye 2018 Nov 3. Epub 2018 Nov 3.

Private American Hospital, Gaziantep, Turkey.

Purpose: To evaluate topographic measurements of the anterior segment and densitometric measurements of the cornea and lens by Pentacam HR in different trimesters of pregnancy.

Methods: This prospective study included 150 healthy pregnant women in their first, second, or third trimester (Groups 1, 2 and 3, respectively) and 54 non-pregnant healthy women (Group 0). Topographic measurements, including central corneal thickness (CCT), corneal volume (CV), anterior chamber depth (ACD), corneal densitometry (CD) and lens densitometry (LD), were done with the Pentacam HR (Oculus, Wetzlar, Germany). Read More

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http://dx.doi.org/10.1016/j.clae.2018.10.016DOI Listing
November 2018
9 Reads

Improving your spectacle patients' in-practice experience with contact lenses during frame selection.

Cont Lens Anterior Eye 2018 Nov 1. Epub 2018 Nov 1.

Independent optometrist, United States.

Purpose: A market research survey was conducted to assess the impact of offering complimentary contact lenses (CLs) to spectacle-only wearing patients during frame selection with regards to their in-office experience, the transaction amount for their eyewear purchase and the likelihood of proceeding with a comprehensive contact lens fitting.

Methods: Five optometry offices in the US participated. An initial interviewing phase served as a control during which optometrists treated spectacle-only wearing patients in the usual manner for frame selection. Read More

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http://dx.doi.org/10.1016/j.clae.2018.10.013DOI Listing
November 2018
10 Reads

Potential contraindications to scleral lens wear.

Cont Lens Anterior Eye 2019 Feb 2;42(1):92-103. Epub 2018 Nov 2.

OD, Private practice, Miami, USA. Electronic address:

Research and reviews have resulted in clear indications for scleral lens (SL) wear. Those indications include visual rehabilitation; therapeutic use in managing ocular surface diseases, lid and orbit disorders; and refractive correction to enhance visual quality, comfort and quality of life. In some cases, the use of SLs may be contraindicated: the presence of low endothelial cell density; Fuchs' endothelial corneal dystrophy; glaucoma (because of the risk of an increase in intraocular pressure and the existence and location of draining devices and blebs); or overnight wear. Read More

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http://dx.doi.org/10.1016/j.clae.2018.10.024DOI Listing
February 2019
19 Reads

In vivo anterior scleral morphometry, axial length and myopia.

Cont Lens Anterior Eye 2018 Nov 1. Epub 2018 Nov 1.

Department of Ophthalmology, Antwerp University Hospital, Edegem, Belgium; Department of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.

Purpose: To in-vivo quantify differences in anterior scleral shape between myopes and emmetropes and relate them with axial length and refractive power.

Methods: Forty-two participants (84 eyes) were included in this study. Twenty-five participants were categorised as emmetropes and seventeen participants were categorised as myopes. Read More

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http://dx.doi.org/10.1016/j.clae.2018.10.021DOI Listing
November 2018
12 Reads

Scleral lens fitting and assessment strategies.

Cont Lens Anterior Eye 2019 Feb 31;42(1):9-14. Epub 2018 Oct 31.

The Ohio State University, Columbus, Ohio, United States.

Purpose: To describe prescriber reported scleral lens fitting and assessment strategies.

Methods: The SCOPE (Scleral Lenses in Current Ophthalmic Practice Evaluation) study group designed and administered an IRB approved, electronic survey (REDCap) regarding current scleral lens fitting and assessment methods. The survey was distributed to attendees of the 2017 Global Specialty Lens Symposium. Read More

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http://dx.doi.org/10.1016/j.clae.2018.10.020DOI Listing
February 2019
9 Reads

Translation and validation of the contact lens dry eye questionnaire-8 (CLDEQ-8) to the Spanish language.

Cont Lens Anterior Eye 2018 Oct 30. Epub 2018 Oct 30.

Cornea and Refractive Surgery Services, Hospital "Dr. Luis Sanchez Bulnes", Asociacion para Evitar la Ceguera en Mexico, Mexico.

Purpose: To present the process of cultural and psychometric adaptation, and clinical validation of a new version in the Spanish language of the Contact Lens Dry Eye Questionnaire-8 (CLDEQ-8).

Materials And Methods: The translation-retro-translation method was applied to the CLDEQ-8 questionnaire. Two independent native Spanish-speaking translators adapted the questionnaire from English to Spanish, and then a committee of experienced clinicians (CE) evaluated the semantic equivalence and designed a Spanish version of the CLDEQ-8 questionnaire. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13670484173041
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http://dx.doi.org/10.1016/j.clae.2018.10.015DOI Listing
October 2018
18 Reads

Long-term effect of corneoscleral contact lenses on refractory ocular surface diseases.

Cont Lens Anterior Eye 2018 Oct 30. Epub 2018 Oct 30.

Department of Ophthalmology, Seoul National University College of Medicine, 103 Daehak-ro, Jongno-gu, Seoul 03080, Republic of Korea; Laboratory of Ocular Regenerative Medicine and Immunology, Seoul Artificial Eye Center, Seoul National University Hospital Biomedical Research Institute, 101 Daehak-ro, Jongno-gu, Seoul 03080, Republic of Korea. Electronic address:

Purpose: To report the therapeutic effect of corneoscleral contact lenses (CLs) with a diameter of 14.0 mm on the refractory ocular surface diseases.

Methods: Medical records of 13 eyes (of nine patients) attempted for fitting with corneoscleral CLs for the management of the severe refractory ocular surface diseases were retrospectively reviewed including Stevens-Johnson syndrome (SJS; eight eyes) and chronic ocular graft-versus-host disease (GVHD; five eyes). Read More

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http://dx.doi.org/10.1016/j.clae.2018.10.011DOI Listing
October 2018
11 Reads

Differences between tears of contact lens wearers studied by photon correlation spectroscopy.

Cont Lens Anterior Eye 2018 Oct 23. Epub 2018 Oct 23.

University of Milano Bicocca, Materials Science Department, via R. Cozzi 55, I-20125, Milan, Italy; University of Milano Bicocca, COMiB, via R. Cozzi 55, I-20125, Milan, Italy. Electronic address:

Purpose: The purpose was to evaluate if there are differences between tears of contact lens (CL) wearers of different materials detectable by measuring the hydrodynamic diameter of tear components through photon correlation spectroscopy (PCS).

Methods: Tears of 59 CL wearers and tears of 39 non-wearers were collected by glass capillary. Wearers were divided into groups depending on the CL material: (i) hydrogels of II FDA group (H-II, 15 subjects), (ii) hydrogels of IV FDA group (H-IV, 13 subjects), (iii) silicone hydrogels (SH, 31 subjects). Read More

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http://dx.doi.org/10.1016/j.clae.2018.10.004DOI Listing
October 2018
11 Reads

Pre-treatment observation of axial elongation for evidence-based selection of children in Hong Kong for myopia control.

Cont Lens Anterior Eye 2018 Oct 23. Epub 2018 Oct 23.

School of Optometry, The Hong Kong Polytechnic University, Kowloon, Hong Kong Special Administrative Region, China.

Purpose: This study aimed to develop evidence-based guidelines for identifying suitable subjects for myopia control using orthokeratology (ortho-k).

Methods: Changes in axial elongation (AE) in the worse eyes of 66 myopic children (myopia between -0.75 and -4. Read More

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http://dx.doi.org/10.1016/j.clae.2018.10.006DOI Listing
October 2018
4 Reads

On the reliability (repeatability) of single pachymetry measures taken with specular microscope-based assessments of the human corneal endothelium.

Cont Lens Anterior Eye 2018 Oct 20. Epub 2018 Oct 20.

Department of Vision Sciences, Glasgow Caledonian University, Cowcaddens Road, Glasgow, G4 OBA, United Kingdom. Electronic address:

Purpose: To assess agreement between 3 measures of central corneal thickness (CCT) taken over a few minutes from nominally normal eyes with a non-contact specular microscope.

Methods: 100 eyes from 100 healthy adults (with an average age of 22 y) were assessed using the Topcon 3000 P instrument to obtain a high quality image of the endothelium and pachymetry.

Results: The group mean CCT values from the 1st, 2nd and 3rd measures were 0. Read More

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http://dx.doi.org/10.1016/j.clae.2018.10.008DOI Listing
October 2018
10 Reads

An approach for simulating the fitting of rigid gas-permeable contact lenses using 3D printing technology.

Cont Lens Anterior Eye 2018 Oct 15. Epub 2018 Oct 15.

Department of Ophthalmology, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, China. Electronic address:

Objective: To introduce a new approach to simulatethe fitting process of rigid gas-permeable (RGP) contact lenses using 3D printing technology.

Methods: A hemispherical or parabolic 3D model was created using 3D Builder or Tinkercad software. The horizontal and vertical diameters and the hemispherical or ellipsoid height were adjusted to simulate different morphologies of the corneal anterior surface. Read More

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http://dx.doi.org/10.1016/j.clae.2018.10.003DOI Listing
October 2018
2 Reads