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    Classification of consumer products under the EU CLP Regulation: what to consider when caring for contact dermatitis patients.
    Contact Dermatitis 2017 Nov 17. Epub 2017 Nov 17.
    Department of Dermatology, University Hospital Jena, 07743, Jena, Germany.
    Possibly hazardous chemical substances and mixtures need to be clearly and correctly classified and labelled, in order for their hazards to be properly identified and communicated. As dermatologists may encounter cases of harm to patients induced by chemicals, such as chemical burns, and irritant and allergic contact dermatitis, it is essential for them to be aware of the EU CLP Regulation and its potential pitfalls. Manufacturers are required by CLP to classify their products according to the rules given in the CLP Regulation. Read More

    Pathomechanisms of Contact Sensitization.
    Curr Allergy Asthma Rep 2017 Nov 11;17(12):83. Epub 2017 Nov 11.
    Allergy Research Group, Department of Dermatology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Hauptstrasse 7, 79104, Freiburg im Breisgau, Germany.
    Contact sensitization is the initial process involved in the development of an allergic reaction to xenobiotic environmental substances. Here, we briefly describe the differences between irritant and allergic contact dermatitis. Then, we highlight the essential steps involved in the development of an ACD reaction, i. Read More

    Allergic contact dermatitis caused by calcipotriol.
    Contact Dermatitis 2017 Nov 8. Epub 2017 Nov 8.
    Contact Allergy Unit, Department of Dermatology, University Hospitals KU Leuven, 3000, Leuven, Belgium.
    Background: Calcipotriol, a synthetic vitamin D analogue, is widely used for the topical treatment of psoriasis. It often causes irritant reactions, whereas allergic contact dermatitis has less commonly been reported.

    Objectives: To report on 6 patients (among them an 11-year-old child) who presented with eczematous lesions complicating pre-existing dermatitis, observed in our tertiary referral patch test clinic between 2004 and 2016. Read More

    Occupational hand eczema and/or contact urticaria: factors associated with change of profession or not remaining in the workforce.
    Contact Dermatitis 2017 Oct 27. Epub 2017 Oct 27.
    Department of Dermatology, Bispebjerg University Hospital, 2400, Copenhagen, Denmark.
    Background: Occupational hand eczema and/or contact urticaria may have social consequences such as change of profession or not remaining in the workforce.

    Objectives: To identify factors associated with job change in a cohort of participants with recognised occupational hand eczema/contact urticaria METHODS: A registry-based study including 2703 employees with recognised occupational hand eczema/contact urticaria in Denmark in 2010/2011. Four to five years later the participants received a follow-up questionnaire, comprising questions on current job situation (response rate 58. Read More

    Propylene Glycol in Contact Dermatitis: A Systematic Review.
    Dermatitis 2017 Oct 23. Epub 2017 Oct 23.
    From the *Department of Internal Medicine, Loma Linda University, CA; †Clinical Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL; and ‡Department of Dermatology, Loma Linda University, CA.
    Propylene glycol (PG), an emollient and emulsifier found in cosmetics, medications, and food, has been granted the dubious honor of being named the American Contact Dermatitis Society's Allergen of the Year for 2018. Contact, systemic, and irritant cutaneous reactions have been documented for PG, which has become an increasingly common ingredient. Propylene glycol is as contentious as it is ubiquitous because it acts as both a weak sensitizer and an irritant, confounding the results of positive patch tests. Read More

    Allergen of the Year: Propylene Glycol.
    Dermatitis 2017 Nov 10. Epub 2017 Nov 10.
    From the *Department of Dermatology, Loma Linda University, CA and †Northwestern University, Chicago, IL.
    Propylene glycol (PG), an emollient and emulsifier found in cosmetics, medications, and food, has been granted the dubious honor of being named the American Contact Dermatitis Society's Allergen of the Year for 2018. Allergic and irritant contact dermatitis and systemic cutaneous reactions to PG, which has become an increasingly common ingredient, have been documented. Propylene glycol is as contentious as it is ubiquitous because it acts as both a weak sensitizer and an irritant, confounding the results of positive patch tests. Read More

    Diagnosis and management of diaper dermatitis in infants with emphasis on skin microbiota in the diaper area.
    Int J Dermatol 2017 Oct 6. Epub 2017 Oct 6.
    Faculty of Medicine, Department of Pediatrics, University of Maribor, Maribor, Slovenia.
    Diaper dermatitis is the most common inflammatory skin eruption within the diaper area in infants and toddlers. Although it rarely causes problems for prolonged periods of time, it causes considerable distress for both infants and parents. Diapered skin is exposed to friction, excessive hydration, varying pH, and is in constant contact with urine and feces, both of which are highly irritant to the skin. Read More

    Paederus Dermatitis: A Case Series.
    Indian Dermatol Online J 2017 Sep-Oct;8(5):361-364
    Department of Dermatology, Venereology and Leprology, JSS Medical College and Hospital, Mysuru, Karnataka, India.
    Vorderman (1901) was the first to record blisters caused by beetles in medical literature. Blister beetle dermatitis is a cutaneous condition caused by the toxins released by blister beetles. The vesicant chemical in the body fluids of these insects causes an acute irritant contact dermatitis characterized by erythematovesicular lesions associated with burning sensation on exposed parts of the body. Read More

    The association of smoking with contact dermatitis and hand eczema - a review.
    Int J Dermatol 2017 Sep 27. Epub 2017 Sep 27.
    Department of Dermatology, Saint Louis University School of Medicine, St. Louis, MO, USA.
    Given the high prevalence of allergic contact dermatitis (ACD), irritant contact dermatitis (ICD), hand eczema (HE), and smoking, and the impact that smoking has on skin disease, the authors reviewed the existing literature to assess the association between smoking and contact dermatitis or hand eczema. Using the PubMed and SCOPUS databases, a literature search identified articles related to allergic contact dermatitis, irritant contact dermatitis, and hand eczema and a possible association with smoking. The search period included articles prior to and including April 2016. Read More

    Characterization of reconstructed human skin containing Langerhans cells to monitor molecular events in skin sensitization.
    Toxicol In Vitro 2018 Feb 21;46:77-85. Epub 2017 Sep 21.
    Institute of Pharmacy (Pharmacology and Toxicology), Freie Universität Berlin, Berlin, Germany. Electronic address:
    Human cell-based approaches to assess defined key events in allergic contact dermatitis (ACD) are well-established, but lack cutaneous penetration and biotransformation as well as cellular cross-talk. Herein, we integrated in vitro-generated immature MUTZ-3-derived Langerhans-like cells (MUTZ-LCs) or monocyte-derived LC-like cells (MoLCs) into reconstructed human skin (RHS), consistent of a stratified epidermis formed by primary keratinocytes on a dermal compartment with collagen-embedded primary fibroblasts. LC-like cells were mainly localized in the epidermal compartment and distributed homogenously in accordance with native human skin. Read More

    A Case of a Paediatric Patient With Allergic Contact Dermatitis to Benzoyl Peroxide.
    J Cutan Med Surg 2017 Sep 1:1203475417733462. Epub 2017 Sep 1.
    1 Division of Dermatology, University of Toronto, Toronto, ON, Canada.
    Allergic contact dermatitis to benzoyl peroxide can occur in up to 6.5% of those with a history of exposure to this potential allergen. Conversely, irritant contact dermatitis is very common with benzoyl peroxide and can be differentiated from allergic contact dermatitis based on the patient's history and clinical signs and symptoms. Read More

    Bullous cutaneous larva migrans: case series and review of atypical clinical presentations.
    G Ital Dermatol Venereol 2017 Oct;152(5):516-519
    Department of Pathophysiology and Transplantation, Università degli Studi di Milano, I.R.C.C.S. Foundation Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.
    Hookworm-related cutaneous larva migrans (HRCLM) is caused by the penetration and migration in the epidermis of larvae of Ancylostoma braziliense and Ancylostoma caninum. It is characterized by slightly raised and erythematous tracks, located especially on the feet. These tracks may be single or multiple, serpiginous or linear, ramified and intertwined, accompanied by pruritus. Read More

    Atopic dermatitis: addressing allergy, infection, itch and complementary therapies.
    Semin Cutan Med Surg 2017 Sep;36(3):112-117
    Department of Medicine, State University of New York at Stony Brook, NY; Allergy & Immunology Training Program, Winthrop University Hospital, Mineola, New York, USA.
    Atopic dermatitis (AD) is a complex condition that results from the dynamic interplay between genetic predisposition, skin barrier defects, environmental factors, and a dysfunctional immune system. As a result, AD can be complicated by irritant and allergic contact dermatitis and imbalances in the skin microbiome, which can subsequently exacerbate the severity and complicate the course of preexisting atopic disease. Itch is an important symptom of AD, as it plays a large role in the quality of life of patients and their families. Read More

    Effects of Acupuncture on 1-chloro-2,4-dinitrochlorobenzene-induced Allergic Contact Dermatitis in Mice.
    J Acupunct Meridian Stud 2017 Aug 11;10(4):252-260. Epub 2017 Jul 11.
    Shandong Medicine Technician College, Tai'an, Shandong, China. Electronic address:
    Allergic contact dermatitis (ACD) is a chronic inflammatory skin disease. Topical corticosteroids are the first-line therapy for ACD despite their significant adverse effects. Acupuncture has been widely used in the treatment of various skin diseases, but its underlying mechanism remains unrevealed. Read More

    Benzalkonium Chloride: An Irritant and Sensitizer.
    Dermatitis 2017 Nov/Dec;28(6):346-352
    From the *Tufts University School of Medicine and †Department of Dermatology, Brigham and Women's Hospital, Boston, MA.
    Background: Benzalkonium chloride (BAK) is a known irritant, and potentially cross-reacting quaternary ammonium compounds are commonly used as preservatives in personal care products.

    Objective: The aim of the study was to review positive reactions to BAK in 615 patients patch tested for suspected allergic contact dermatitis.

    Methods: A retrospective chart review was performed in 615 patients patch tested from June 2015 to October 2016. Read More

    Skin targeting of curcumin solid lipid nanoparticles-engrossed topical gel for the treatment of pigmentation and irritant contact dermatitis.
    Artif Cells Nanomed Biotechnol 2017 Sep 8:1-12. Epub 2017 Sep 8.
    a Sinhgad College of Pharmacy , Pune , India.
    Irritant contact dermatitis (ICD) and hyperpigmentation are the problems associated with skin. Topical curcumin (CUR) although effective in hyperpigmentation and ICD, is a challenging molecule due to low-solubility. Encapsulation of CUR into solid lipid nanoparticles (SLNs) makes it amenable to topical dosing as their small size promotes its penetration into the skin. Read More

    Best practices, new perspectives and the perfect emollient: optimizing the management of contact dermatitis.
    J Dermatolog Treat 2017 Sep 19:1-11. Epub 2017 Sep 19.
    e Department of Dermatology , University of Kiel , Kiel , Germany.
    Contact dermatitis (CD) is caused by environmental agents, irritants, and allergens that penetrate the epidermis and lead to inflammation. An intact skin barrier prevents penetration and is important in maintaining healthy skin. Classical diagnosis of CD is made using the patch test, and traditional treatment strategies for CD promote skin barrier integrity and resolve the inflammatory component of the condition. Read More

    [Hand eczema in children. Clinical and epidemiological study of the population referred to a tertiary hospital].
    An Pediatr (Barc) 2017 Aug 21. Epub 2017 Aug 21.
    Servicio de Dermatología, Hospital General Universitario de Valencia, Valencia, España.
    Introduction: Hand eczema is a frequent disease in adults. Diagnosing the cause of hand eczema is difficult due to different classifications. There is lack of evidence on hand eczema and its causes in children. Read More

    Hairdressers' skin exposure to hair dyes during different hair dyeing tasks.
    Contact Dermatitis 2017 Nov 9;77(5):303-310. Epub 2017 Aug 9.
    Institute of Environmental Medicine, Karolinska Institutet, 171 77, Stockholm, Sweden.
    Background: The high risk of occupational skin disease among hairdressers, caused by skin exposure to irritants and sensitizers, such as hair dye substances, is of great concern.

    Objectives: The aim of the present study was to assess how the various tasks involved in hair dyeing contribute to hairdressers' exposure to hair dye, in order to enable the formulation of well-founded recommendations on working routines that will reduce exposure and prevent occupational disease.

    Methods: Skin exposure to hair dye was measured for 20 hairdressers applying highlights and all-over hair colour with the hand rinsing technique. Read More

    An observational study on the effects of aviation turbine fuel and lubricants on the skin of Indian Air Force ground crew in flying stations.
    Med J Armed Forces India 2017 Jul 11;73(3):294-298. Epub 2016 Aug 11.
    Assistant Surgeon, O/o Deputy Director Medical Services (Leprosy), Collectorate, Salem District, Tamil Nadu 636001, India.
    Background: Ground crew of the Air Force routinely handle aviation turbine fuel (ATF) and lubricants and a need was felt to study the adverse effects of these substances on their skin so that remedial measures could be taken to prevent these adverse effects.

    Methods: A multi-centric, cross-sectional, observational study was performed at three Air Force flying stations. 109 ground crew members of the Indian Air Force (IAF) who were in direct contact with ATF and lubricants were screened for dermatological manifestations on exposed areas. Read More

    Skin diseases of the vulva: eczematous diseases and contact urticaria.
    J Obstet Gynaecol 2017 Aug 7:1-6. Epub 2017 Aug 7.
    a Department of Dermatology , Bispebjerg Hospital , Copenhagen , Denmark.
    Skin diseases in the vulvar area include a variety of disorders many of which have a chronic course with significant morbidity. It is important to be aware of the symptoms, signs and diagnostic tools in order to optimise treatment. Herein, the most common eczematous diseases of the vulvar area, i. Read More

    Atopic and Contact Dermatitis of the Vulva.
    Obstet Gynecol Clin North Am 2017 Sep;44(3):371-378
    Department of Dermatology, Wake Forest University School of Medicine, 4618 Country Club Road, Winston-Salem, NC 27104, USA. Electronic address:
    Pruritus, or itch, is a common vulvar complaint that is often treated empirically as a yeast infection; however, yeast infections are just one of the many conditions that can cause vulvar itch. Ignoring other conditions can prolong pruritus unnecessarily. Atopic dermatitis, irritant contact dermatitis, and allergic contact dermatitis are extremely common noninfectious causes of vulvar itch that are often underdiagnosed by nondermatologists. Read More

    Dermatitis of the Foot: Epidemiologic and Clinical Features in 389 Children.
    Pediatr Dermatol 2017 Sep 21;34(5):535-539. Epub 2017 Jul 21.
    Dermatology Department, Valencia University General Hospital, Valencia, Spain.
    Background/objectives: Footwear dermatitis is a form of contact dermatitis resulting from exposure to shoes. There have been only small studies regarding foot contact dermatitis in children. The present study was undertaken to define the prevalence and epidemiologic and clinical features of shoe dermatitis in children. Read More

    A Case of Ischemia-Induced Perianal Ulceration Mimicking Pyoderma Gangrenosum.
    Skinmed 2017 1;15(3):235-237. Epub 2017 Jun 1.
    Department of Dermatology, Antrim Area Hospital, Antrim, Northern Ireland.
    A 68-year-old woman, with a 75-pack-year smoking history and a history of chronic excess alcohol intake, presented with a 5-week history of worsening perianal pain and ulceration. She recently had an inpatient admission with back pain and urinary tract infection during which she developed diarrhea and fecal incontinence. Initially, the perianal ulceration was diagnosed as severe irritant contact dermatitis and treated with barrier creams and topical clobetasone 17-butyrate 0. Read More

    Intestinal Stomas-Postoperative Stoma Care and Peristomal Skin Complications.
    Clin Colon Rectal Surg 2017 Jul 22;30(3):184-192. Epub 2017 May 22.
    Section of Colon and Rectal Surgery, Department of General Surgery, University of Chicago Medicine, Chicago, Illinois.
    Intestinal stomas are necessary for several colon and rectal conditions and represent a major change in the new ostomate's daily life. Though dehydration is the most frequent etiology requiring readmission, irritant contact dermatitis and a host of other peristomal skin conditions are more common complications for ostomates. Wound, ostomy, and continence nurses are invaluable resources to both ostomy patients and providers. Read More

    Skin Health Connected to the Use of Absorbent Hygiene Products: A Review.
    Dermatol Ther (Heidelb) 2017 Sep 30;7(3):319-330. Epub 2017 Jun 30.
    SCA Hygiene Products AB, Göteborg, Sweden.
    Over the past 50 years, absorbent hygiene products such as baby diapers and incontinence products have become essential features of modern day life. Through innovation and enhanced technology, their design, composition and performance have been dramatically upgraded from their early forms, and they have transformed the lives of millions of people, improving their quality of life. Skin health related to the use of absorbent hygiene products has accordingly also greatly improved. Read More

    Minimum standards on prevention, diagnosis and treatment of occupational and work-related skin diseases in Europe - position paper of the COST Action StanDerm (TD 1206).
    J Eur Acad Dermatol Venereol 2017 Jun;31 Suppl 4:31-43
    Department of Dermatology, Hospital del Mar, Institut Mar d´Investigacions Mèdiques (IMIM), Universitat Autònoma de Barcelona, Barcelona, Spain.
    Background: Skin diseases constitute up to 40% of all notified occupational diseases in most European countries, predominantly comprising contact dermatitis, contact urticaria, and skin cancer. While insufficient prevention of work-related skin diseases (WRSD) is a top-priority problem in Europe, common standards for prevention of these conditions are lacking.

    Objective: To develop common European standards on prevention and management of WRSD and occupational skin diseases (OSD). Read More

    Nickel Sulfate Promotes IL-17A Producing CD4+ T Cells by an IL-23-Dependent Mechanism Regulated by TLR4 and Jak-STAT Pathways.
    J Invest Dermatol 2017 Oct 17;137(10):2140-2148. Epub 2017 Jun 17.
    Inflammation Chimiokines et Immunopathologie, INSERM, Fac. de pharmacie-Univ. Paris-Sud, Université Paris-Saclay, Châtenay-Malabry, France. Electronic address:
    Allergic contact dermatitis, caused by nickel, is a delayed-type hypersensitivity reaction, and 14.5% of the general population may be affected in Europe. Among a wide range of cytokines, the IL-12 family has unique structural and immunological characteristics. Read More

    [Avoiding peristomal skin problems].
    Rev Infirm 2017 Jun - Jul;66(232):32-34
    Unité de chirurgie colorectale, Cliniques universitaires Saint-Luc, Avenue Hippocrate, 10 1200 Bruxelles, Belgique. Electronic address:
    Peristomal irritation is one of the most common complications in patients with a stoma. In many cases, prevention is limited to the care provided during the post-operative period. However, it can start before the operation by improving the physical condition of the patient. Read More

    Paederus dermatitis.
    Indian J Dermatol Venereol Leprol 2017 Jul-Aug;83(4):424-431
    Department of Ophthalmology, Karpaga Vinayaga Institute of Medical Sciences and Research Center, Madhuranthakam, Tamil Nadu, India.
    Paederus dermatitis is an irritant dermatitis caused by pederin, a toxin produced by the rove beetle (Paederus). The disease occurs worldwide, but it is often not recognized as a history of contact with the insect is frequently absent. It is commonly seen in the rainy season. Read More

    Management of Atopic Hand Dermatitis.
    Dermatol Clin 2017 Jul;35(3):365-372
    Department of Dermatology and Allergy, Herlev and Gentofte Hospital, University of Copenhagen, Kildegårdsvej 28, Hellerup DK-2900, Denmark; National Allergy Research Centre, Herlev and Gentofte Hospital, University of Copenhagen, Kildegårdsvej 28, Hellerup DK-2900, Denmark. Electronic address:
    This article provides an overview of clinical aspects of hand eczema in patients with atopic dermatitis. Hand eczema can be a part of atopic dermatitis itself or a comorbidity, for example, as irritant or allergic contact dermatitis. When managing hand eczema, it is important to first categorize the subtype and identify potential culprit allergens or irritants. Read More

    A Descriptive Study to Explore the Effect of Peristomal Skin Complications on Quality of Life of Adults With a Permanent Ostomy.
    Ostomy Wound Manage 2017 May;63(5):10-23
    New York University Lutheran Medical Center, Brooklyn, NY.
    Approximately 1 million people are living with an ostomy, and 100 000 to 130 000 new ostomies are created each year. The exact incidence and prevalence of complications are unknown but have been reported to be as high as 70% and to affect quality of life (QoL). Using convenience sampling methods, a descriptive study was conducted to explore QoL scores and peristomal complications reported by adults with a permanent ostomy attending the 2009 United Ostomy Associations of America conference. Read More

    Dermatology in Ghana: a retrospective review of skin disease at the Korle Bu Teaching Hospital Dermatology Clinic.
    Pan Afr Med J 2017 3;26:125. Epub 2017 Mar 3.
    The Ronald Perelman Department of Dermatology, New York University School of Medicine, USA.
    Introduction: Ghana is currently developing its provision of dermatology services. Epidemiologic studies of the skin diseases seen by Ghanaian dermatologists are needed to guide these efforts. We aimed to describe the skin conditions seen by and management practices of Ghanaian dermatologists in a specialized clinic. Read More

    [Skin diseases associated with environmental factors].
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 2017 Jun;60(6):605-617
    Abteilung Allergologie, Paul-Ehrlich-Institut, Paul-Ehrlich-Str. 51-59, 63225, Langen, Deutschland.
    Background: Multiple environmental exposures may derange the regulatory and repair mechanisms of the skin and lead to dermatological disease.

    Objectives: Provide an overview of non-allergic skin diseases associated with environmental factors.

    Materials And Methods: Review of current scientific evidence for associations of non-allergic skin diseases with environmental exposures: irritation, chemicals, infection, UV-radiation, temperature. Read More

    Dermatitis Due to Paederus Colombinus: Report of an Epidemic Outbreak of 68 Cases in the Province of Darien, Panama.
    Cureus 2017 Apr 12;9(4):e1158. Epub 2017 Apr 12.
    Public Health and Infection Research Group, Faculty of Health Sciences, Universidad Tecnológica De Pereira, Pereira, Risaralda, Colombia.
    Introduction: Contact dermatitis due to Paederus is a particular form of accident by animal contact. It is characterized by the sudden onset of erythematous and vesicular lesions with burning sensation on exposed areas of the body. The aim of this study was to describe the epidemiological and clinical findings of an outbreak of Paederus dermatitis in Panama. Read More

    Allergic and nonallergic rhinitis and skin sensitization to metals: is there a link?
    Eur Ann Allergy Clin Immunol 2017 May;49(3):106-109
    Allergy and Respiratory Diseases, IRCCS San Martino-Ist-University of Genoa, Genoa, Italy. Phone: +39 010 353 8904 E-mail:
    Summary: Background. Chromium, Cobalt and Nickel are responsible for contact dermatitis, that is largely prevalent in the general population. They can act also as irritants in the upper and lower respiratory airways. Read More

    Current knowledge on biomarkers for contact sensitization and allergic contact dermatitis.
    Contact Dermatitis 2017 Jul 12;77(1):1-16. Epub 2017 May 12.
    Department of Dermatology and Allergy, National Allergy Research Centre, Herlev and Gentofte Hospital, University of Copenhagen, 2900, Hellerup, Denmark.
    Contact sensitization is common and affects up to 20% of the general population. The clinical manifestation of contact sensitization is allergic contact dermatitis. This is a clinical expression that is sometimes difficult to distinguish from other types of dermatitis, for example irritant and atopic dermatitis. Read More

    Medical adhesive-related skin injuries associated with vascular access.
    Br J Nurs 2017 Apr;26(8):S4-S12
    Tissue Viability Lead Nurse, Imperial College Healthcare NHS Trust, London.
    Establishing vascular access and preventing infection, both at insertion and during ongoing care is generally the top priority; the maintenance of optimal skin integrity is often a distant secondary consideration. Skin can react to different types of dressings or adhesives, or problems can arise relating to the securement of lines or the development of sensitivities to cleaning solutions. Clearly, these scenarios are not limited to the securement of vascular access devices; however, a patient with a long-term vascular access device may not have other options for vascular access, which makes this a very important and yet largely unrecognised area. Read More

    Contact sensitizers trigger human CD1-autoreactive T-cell responses.
    Eur J Immunol 2017 Jul 23;47(7):1171-1180. Epub 2017 May 23.
    Singapore Immunology Network, Agency for Science, Technology and Research, Singapore.
    Allergic contact dermatitis is a primarily T-cell-mediated inflammatory skin disease induced by exposure to small molecular-weight haptens, which covalently bind to proteins. The abundance of cutaneous T cells that recognize CD1a antigen-presenting molecules raises the possibility that MHC-independent antigen presentation may be relevant in some hapten-driven immune responses. Here we examine the ability of contact sensitizers to influence CD1-restricted immunity. Read More

    Garlic Dermatitis on the Neck of an Infant Treated for Nasal Congestion.
    Pediatr Dermatol 2017 Jul 19;34(4):e212-e213. Epub 2017 Apr 19.
    Division of Dermatology, Ann and Robert H. Lurie Children's Hospital of Chicago, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
    The health benefits of garlic (Allium sativum) as a naturopathic remedy have been well documented, but topical application of garlic has been linked to allergic and irritant contact dermatitis. We present a case of severe irritant contact dermatitis due to application of a fresh garlic necklace to the neck of infant for treatment of nasal congestion. Read More

    Myths on Chemical Burns in the Diaper Area.
    Clin Pediatr (Phila) 2017 May;56(5_suppl):13S-15S
    1 Kenwood Dermatology, Cincinnati, OH, USA.
    Over the past several years, a number of articles and online posts have circulated on the Internet associating use of disposable and cloth diapers with chemical burns on babies' skin. Because both mild chemical burns and diaper dermatitis (diaper rash) can cause skin redness and peeling, it is not surprising that some confusion has arisen regarding the association between these two conditions. However, diapers cannot cause chemical burns because they are made of inert materials. Read More

    Differential Diagnosis of Diaper Dermatitis.
    Clin Pediatr (Phila) 2017 May;56(5_suppl):16S-22S
    1 Johns Hopkins Children's Center, Baltimore, MD, USA.
    Mild diaper dermatitis often occurs in children before toilet training is complete, particularly from 9 to 12 months of age, and the most common presentation is an irritant contact dermatitis. Diaper dermatitis may account for up to 25% of dermatology visits to health care providers during the first year of life. Fortunately, since the introduction of hypoallergenic, superabsorbent modern disposable diapers, the incidence and severity of irritant and allergic contact dermatitis has decreased dramatically. Read More

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