4,902 results match your criteria Contact Dermatitis Irritant


Patch testing and diagnosis when suspecting allergic contact dermatitis from medical devices.

Contact Dermatitis 2020 Jul 1. Epub 2020 Jul 1.

Department of Occupational and Environmental Dermatology, Lund University, Skåne University Hospital, Malmö, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cod.13650DOI Listing

A cross-sectional study to analyze the clinical subtype, contact sensitization and impact of disease severity on quality of life and cost of illness in patients of hand eczema.

Indian J Dermatol Venereol Leprol 2020 Jun 26. Epub 2020 Jun 26.

Department of Dermatology and STD, University College of Medical Sciences and Associated Guru Teg Bahadur Hospital, University of Delhi, Delhi, India.

Background: The high incidence, chronicity, frequent recurrences and severity of hand eczema leads to a massive impact on the quality of life. Despite great medical and socioeconomic importance, there is a paucity of data that addresses the cost of illness and economic factors associated with hand eczema. Most of the studies have originated from Europe and none have been reported from India. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/ijdvl.IJDVL_333_18DOI Listing

Skin diseases affecting a population occupationally exposed to terrestrial fauna and flora in Brittany over a 15-year period.

Ann Agric Environ Med 2020 Jun 31;27(2):211-218. Epub 2020 Mar 31.

Centre Hospitalier Régional (CHU) Morvan, France.

Introduction And Objective: Brittany is the leading agricultural production region of France where many workers are exposed to the local flora and fauna. The aim of the study is to describe the different skin diseases found among the workers occupationally exposed to the terrestrial fauna and flora in Brittany, and to assess the possible over-representation of some work environments.

Material And Methods: This was a retrospective, descriptive study carried out between 1 October 2002 - 30 April 2017, based on the coding of files from a multi-disciplinary occupational dermatology clinic at the Brest University Hospital. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.26444/aaem/119142DOI Listing

Contact dermatitis: A great imitator.

Clin Dermatol 2020 Mar - Apr;38(2):176-192. Epub 2019 Oct 24.

Department of Dermatology, Faculty of Medicine, Istanbul Medeniyet University, Istanbul, Turkey.

Contact dermatitis (CD) refers to a group of cutaneous diseases caused by contact with allergens or irritants. It is characterized by different stages of an eczematous eruption and has the ability to mimic a wide variety of dermatologic conditions, including inflammatory dermatitis, infectious conditions, cutaneous lymphoma, drug eruptions, and nutritional deficiencies. Irritant CD and allergic CD are the two main presentations of the disease. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clindermatol.2019.10.003DOI Listing
October 2019

Occupational Exposure to Metals and Solvents: Allergy and Airway Diseases.

Curr Allergy Asthma Rep 2020 Jun 6;20(8):38. Epub 2020 Jun 6.

Department of Pharmaceutical Toxicology, Hacettepe University, Faculty of Pharmacy, Ankara, Turkey.

Purpose Of Review: Occupational allergic diseases (OAD) such as occupational contact dermatitis (OCD), occupational asthma (OA), and occupational rhinitis (OR) are the most prevalent occupational diseases in industrialized countries. The purpose of this review is to provide an update about the main occupational metal and solvent exposures related to allergy and airway diseases and to discuss newly defined causative agents and industries in this field.

Recent Findings: Currently for over 400 causative agents for OA and OCD, several hundreds of agents for OR have been identified. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11882-020-00931-7DOI Listing

Approach to occupational contact dermatitis in an industrialized region of Spain.

J Investig Allergol Clin Immunol 2020 Jun 3. Epub 2020 Jun 3.

Department of Allergy and Clinical Immunology, Clínica Universidad de Navarra. Pamplona. Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18176/jiaci.0576DOI Listing

Plant Associated Irritant & Allergic Contact Dermatitis (Phytodermatitis).

Dermatol Clin 2020 Jul 4;38(3):389-398. Epub 2020 May 4.

Dermatology Physicians, Inc., 360 Plaza Drive, Suite C, Columbus, IN 47201, USA; Department of Dermatology, Indiana University School of Medicine, Indianapolis, IN, USA. Electronic address:

With more than 350,000 plant species recognized and new species continually being identified, it is not surprising that humans contact plants or plant-containing products daily. The nearly endless list of potential exposures leaves us with a challenging task when attempting to categorize and study potential plant-related irritants and allergens. This article focused on laying a sound framework for understanding some of the more pertinent potential irritants and allergens. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.det.2020.02.010DOI Listing

Occupational Contact Dermatitis: Evaluation and Management Considerations.

Dermatol Clin 2020 Jul 4;38(3):329-338. Epub 2020 May 4.

Department of Dermatology, Penn State Health, Milton S. Hershey Medical Center, 500 University Drive, Hershey, PA 17033, USA. Electronic address:

This article provides an overview of the evaluation and management of occupational contact dermatitis, including how to evaluate a patient with suspected occupational contact dermatitis. Patch testing, how to perform a site visit, and how to properly manage using preventative measures, prescribed therapies, and patient education are discussed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.det.2020.02.001DOI Listing

Common Allergens and Considerations When Performing Pediatric Patch Testing.

Dermatol Clin 2020 Jul;38(3):321-327

Department of Dermatology, University of Missouri, 1 Hospital Drive, Room MA111, Columbia, MO 65212, USA.

Pediatric allergic contact dermatitis (Ped-ACD) is an increasingly recognized highly prevalent skin disease that has a significant impact on the quality of life of patients and their families. Accurate and appropriate patch testing is vital to diagnosing Ped-ACD. This requires knowledge of the most common allergens in the pediatric population, consideration of concurrent diseases that can complicate the clinical picture, and potential modification of techniques to lessen exposure to irritants and sensitizers while obtaining true positive results. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.det.2020.02.003DOI Listing

Allergic Contact Sensitization in Healthy Skin Differs from Sensitization in Chronic Dermatitis: Atopic, Occupational Wet Work, and Stasis Dermatitis.

Authors:
Susan T Nedorost

Dermatol Clin 2020 Jul 17;38(3):301-308. Epub 2020 Apr 17.

University Hospitals Cleveland Medical Center, Case Western Reserve University, 11100 Euclid Avenue, Lakeside Suite 6223, Cleveland, OH 44106, USA. Electronic address:

The duration of cutaneous inflammation preceding sensitization influences the resulting allergic response; the innate immune system instructs the adaptive immune response. Potent allergens that function as their own irritant cause classic T helper cell type 1 skewed dermatitis. Examples include poison ivy, epoxy resin, and methylchloroisothiazolinone. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.det.2020.02.006DOI Listing

German S1 guidelines for the diagnosis and treatment of perianal dermatitis (anal eczema).

J Dtsch Dermatol Ges 2020 Jun 29;18(6):648-657. Epub 2020 May 29.

Praxis für Enddarmerkrankungen, Heidelberg, Germany.

Perianal dermatitis (anal eczema, perianal eczema) is one of the most common proctological conditions. It may occur as a sequela or a presenting symptom of various proctological, dermatological, allergic or pathogen-induced disorders. The three main types of anal eczema are irritant-toxic, atopic and allergic contact dermatitis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ddg.14125DOI Listing

Onset of occupational hand eczema among healthcare workers during the SARS-CoV-2 pandemic: Comparing a single surgical site with a COVID-19 intensive care unit.

Contact Dermatitis 2020 May 26. Epub 2020 May 26.

Department of Dermatology and Allergy, University Hospital, LMU, Munich, Germany.

Background: As a result of the COVID-19 outbreak, hygiene regulations have been revised and hand sanitation has been intensified.

Objective: To investigate the onset of hand eczema during the COVID-19 pandemic in healthcare workers (HCWs) directly involved in intensive care of COVID-19 patients and HCWs without direct contact with COVID-19 patients. Hereby, we aim at increasing awareness about occupational hand eczema and preventive measures that can be adopted. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cod.13618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7283680PMC

Protecting medical staff from skin injury/disease caused by personal protective equipment during epidemic period of COVID-19: experience from China.

J Eur Acad Dermatol Venereol 2020 May;34(5):919-921

Department of Dermatology, The Second Xiangya Hospital of Central South University, Changsha, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jdv.16388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7280671PMC

The effect of the "stay-at-home" policy on requests for dermatology outpatient clinic visits after the COVID-19 outbreak.

Dermatol Ther 2020 May 13:e13581. Epub 2020 May 13.

Department of Dermatology, State University of New York Downstate, New York, USA.

The Coronavirus Disease 2019 (COVID-19) emerged late in Turkey but it showed a rapid progression later. We aimed to investigate the changes in the number of patients who requested a dermatology outpatient clinic visit due to the increased social and medical burden caused by COVID-19 in Turkey during the first days of the pandemic. We also examined the most common dermatologic diseases diagnosed during the COVID-19 outbreak. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/dth.13581DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272831PMC

Preventing adverse cutaneous reactions from amplified hygiene practices during the COVID-19 pandemic: how dermatologists can help through anticipatory guidance.

Arch Dermatol Res 2020 May 9. Epub 2020 May 9.

Department of Dermatology, Rutgers Robert Wood Johnson Medical School, 1 World's Fair Dr, Ste 2400, Somerset, NJ, 08873, USA.

The COVID-19 pandemic has swept the globe with more than 2,000,000 confirmed cases of SARS-CoV-2 infection in 184 countries and territories. According to the Centers for Disease Control and Prevention (CDC), two crucial actions can reduce the risk of person-to-person viral transmission: frequent hand washing and surface decontamination with specific environmental protection agency (EPA)-registered disinfectants. As hygiene recommendations evolve during the COVID-19 pandemic and community members adopt changing practices, dermatologists are likely to see a rise in adverse cutaneous reactions from prolonged irritant exposures and widespread use of antimicrobials. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02086-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210798PMC

Frequent Hand Washing for COVID-19 Prevention Can Cause Hand Dermatitis: Management Tips.

Cureus 2020 Apr 2;12(4):e7506. Epub 2020 Apr 2.

Physical Medicine and Rehabilitation, "Carol Davila" University of Medicine and Pharmacy, Bucharest, ROU.

Coronavirus disease 2019 (COVID-19) continues to spread globally, outpacing the capacity and resources of health systems worldwide. A therapeutic vaccine is not yet on the rise, and preventive measures are the current approach to restraint the transmission of cases. As the virus is highly contagious via respiratory route (droplets from infected persons, widely spread by coughing or sneezing) and via contact with contaminated surfaces, community transmission and spread can be decreased through the practice of regular and diligent hand hygiene. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7759/cureus.7506DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195203PMC

Occupational dermatoses among healthcare workers in a hospital center in Portugal.

Rev Bras Med Trab 2019 15;17(3):285-291. Epub 2020 Apr 15.

Dermatology Department, North Lisbon Hospital Center - Lisbon, Portugal.

Background: Skin diseases account for more than 35% of occupational diseases, affecting 1/1,000 workers annually.

Objective: To characterize occupational dermatoses affecting hospital workers and identify possible triggers and susceptibility factors.

Methods: Cross-sectional study in which we analyzed information extracted from electronic medical records of workers who performed periodic examinations in the course of one year. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5327/Z1679443520190393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195876PMC

Skin barrier function after repeated short-term application of alcohol-based hand rub following intervention with water immersion or occlusion.

Contact Dermatitis 2020 May 1. Epub 2020 May 1.

Department of Dermatology, University of Copenhagen, Bispebjerg Hospital, Copenhagen, Denmark.

Background: Alcohol-based hand rub (ABHR) is recommended for hand hygiene, and application on dry skin is generally well tolerated. However, hydration of the skin may lead to increased susceptibility to ABHR.

Objectives: To evaluate if increased skin hydration changes skin barrier response to ABHR, as compared to application on dry skin. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cod.13587DOI Listing

Contact Dermatitis Associated With Nail Care Products: Retrospective Analysis of North American Contact Dermatitis Group Data, 2001-2016.

Dermatitis 2020 May/Jun;31(3):191-201

Department of Dermatology, Ohio State University, Columbus.

Background: Ingredients in nail care products may lead to allergic and/or irritant contact dermatitis.

Objective: The aims of this study were to determine frequency of contact dermatitis associated with nail care products, characterize associated body sites, and describe causative allergens.

Methods: A retrospective analysis was conducted with the North American Contact Dermatitis Group data between 2001 and 2016. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/DER.0000000000000583DOI Listing

Frequent handwashing amidst the COVID-19 outbreak: prevention of hand irritant contact dermatitis and other considerations.

Health Sci Rep 2020 Jun 27;3(2):e163. Epub 2020 Apr 27.

Skin Diseases and Leishmaniasis Research Center Isfahan University of Medical Sciences Isfahan Iran.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hsr2.163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185953PMC

Respiratory Symptoms of Exposure to Substances in the Workplace among Bulgarian Dental Students: a Self-report Questionnaire Survey.

Folia Med (Plovdiv) 2020 Mar;62(1):141-146

Medical University of Plovdiv, Plovdiv, Bulgaria.

Background: Dental students are at high risk of developing adverse respiratory reactions as a result of their practical work during their dentistry degree program when they come into contact with multiple airborne irritants and allergens.

Aim: To estimate the prevalence of respiratory symptoms of exposure to substances in the workplace and associated risk factors in Bulgarian dental students.

Results: The prevalence of self-reported respiratory symptoms related to the pre-clinical and clinical training courses of the dentistry program was 12. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3897/folmed.62.e48268DOI Listing

Optoacoustic mesoscopy shows potential to increase accuracy of allergy patch testing.

Contact Dermatitis 2020 Apr 20. Epub 2020 Apr 20.

Department of Dermatology and Allergy, Faculty of Medicine, Technical University of Munich, Munich, Germany.

Background: Differentiation between irritant and allergic skin reactions in epicutaneous patch testing is based largely on subjective clinical criteria, with the risk of high intraobserver and interobserver variability. Novel dermatological imaging using optoacoustic mesoscopy allows quantitative three-dimensional assessment of microvascular biomarkers.

Objectives: We investigated the potential of optoacoustic imaging to improve the precision of patch test evaluation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cod.13563DOI Listing

Use of protective gloves by hairdressers: A review of efficacy and potential adverse effects.

Contact Dermatitis 2020 Apr 20. Epub 2020 Apr 20.

National Allergy Research Center, Department of Dermatology and Allergy, Herlev and Gentofte Hospital, University of Copenhagen, Hellerup, Denmark.

Occupational hand eczema is common among hairdressers, and protective gloves are important in limiting exposure to irritants and allergens. Various glove types may differ in their protective ability, and their use may lead to hand eczema due to skin irritancy and allergy. MEDLINE was searched for studies investigating permeation of gloves to irritants and allergens used in the hairdressing trade, as well as adverse effects of glove use affecting hairdressers. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cod.13561DOI Listing

Atopic Dermatitis: Identification and Management of Complicating Factors.

Int J Mol Sci 2020 Apr 11;21(8). Epub 2020 Apr 11.

Department of Dermatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan.

Atopic dermatitis (AD) is a chronic relapsing inflammatory skin disease, associated with impaired skin barrier function and an atopic background. Various complicating factors, such as irritants, aeroallergens, food, microbial organisms, contact allergens, sweat, and scratching can induce the development of AD symptoms. Irritants, including soap/shampoo and clothes, can cause itching and eczematous lesions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms21082671DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215488PMC

The Efficacy of Colloidal Oatmeal Cream 1% as Add-on Therapy in the Management of Chronic Irritant Hand Eczema: A Double-Blind Study.

Clin Cosmet Investig Dermatol 2020 25;13:241-251. Epub 2020 Mar 25.

Department of Clinical Pharmacy, School of Pharmacy, Hamadan University of Medical Sciences, Hamadan, Iran.

Background: Irritant contact dermatitis (ICD) is the most frequent cause of hand eczema (HE). There is promising evidence with the use of topical oatmeal compounds in the management of inflammation- and itch-responses associated with diverse dermatologic conditions. This study aimed to evaluate the clinical benefit of colloidal oatmeal cream in the management of chronic irritant HE. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2147/CCID.S246021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103792PMC

A case of irritant contact dermatitis and suspected linagliptin-induced koebnerized bullous pemphigoid.

JAAD Case Rep 2020 Apr 25;6(4):316-318. Epub 2020 Mar 25.

Department of Dermatology, University of Missouri-Columbia, Columbia, Missouri.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jdcr.2020.01.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109372PMC

Dupilumab for occupational irritant hand dermatitis in a nonatopic individual: A case report.

JAAD Case Rep 2020 Apr 25;6(4):296-298. Epub 2020 Mar 25.

Department of Dermatology, Stanford University School of Medicine, Redwood City, California.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jdcr.2020.02.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109358PMC

Irritant contact dermatitis after a curious therapeutic use of oregano essential oil.

Contact Dermatitis 2020 Mar 30. Epub 2020 Mar 30.

Department of Medical Sciences, Section of Dermatology, University of Ferrara, Ferrara, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cod.13540DOI Listing

Adverse cutaneous reaction to diabetic glucose sensors and insulin pumps: Irritant contact dermatitis or allergic contact dermatitis?

Contact Dermatitis 2020 Jul 4;83(1):25-30. Epub 2020 May 4.

Department of Dermatology, Cliniques universitaires Saint-Luc, Brussels, Belgium.

Background: Adverse cutaneous reactions to diabetes medical devices (glucose sensors and insulin pumps) are described, notably allergic contact dermatitis (ACD) with isobornyl acrylate (IBOA) and N,N dimethylacrylamide (DMAA) as the main allergen.

Objectives: To determine if all cases of adverse cutaneous reactions observed with diabetes medical devices (ie FreeStyle Libre, Enlite sensors or insulin pumps), referred to our department with suspected allergies are confirmed as ACD.

Patients And Methods: Fifty-two patients who presented skin reactions to diabetes medical devices were patch tested with the European baseline series, a plastic and glues series, a (meth) acrylates series, a piece of the adhesive part of the device, as well as IBOA 0. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cod.13529DOI Listing

Optimizing the Biodistribution of Radiofluorinated Barbiturate Tracers for Matrix Metalloproteinase Imaging by Introduction of Fluorescent Dyes as Pharmacokinetic Modulators.

Bioconjug Chem 2020 Apr 30;31(4):1117-1132. Epub 2020 Mar 30.

Department of Nuclear Medicine, University Hospital Münster, Albert-Schweitzer-Campus 1, Building A1, D-48149 Münster, Germany.

Dysregulated expression or activation of matrix metalloproteinases (MMPs) is observed in many kinds of life-threatening diseases. Therefore, MMP imaging-for example, with radiolabeled MMP inhibitors (MMPIs)-potentially represents a valuable tool for clinical diagnostics using noninvasive single photon emission computed tomography (SPECT) or positron emission tomography (PET) imaging. Despite numerous preclinical imaging approaches, translation to a clinical setting has not yet been successful. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.bioconjchem.9b00817DOI Listing

Work-related skin symptoms among Bulgarian dentists.

Authors:
Iliyana L Stoeva

Contact Dermatitis 2020 Jun 1;82(6):380-386. Epub 2020 Apr 1.

Department of Diagnostic Imaging, Dental Allergology and Physiotherapy, Faculty of Dental Medicine, Medical University Plovdiv, Plovdiv, Bulgaria.

Background: Dentists are at high risk of developing skin symptoms due to occupational contact with irritants and/or allergens.

Objectives: To assess the point prevalence of work-related skin symptoms and associated factors in Bulgarian dentists.

Methods: A cross-sectional study was performed using a self-report questionnaire. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cod.13523DOI Listing

12-year data on skin diseases in the Finnish Register of Occupational Diseases II: Risk occupations with special reference to allergic contact dermatitis.

Contact Dermatitis 2020 Jun 2;82(6):343-349. Epub 2020 Apr 2.

Finnish Institute of Occupational Health (FIOH), Occupational Health Unit, Helsinki, Finland.

Background: Detailed epidemiological studies on occupational skin diseases (OSDs) are scarce.

Objectives: To analyze risk occupations for OSDs in the Finnish Register of Occupational Diseases (FROD).

Methods: We retrieved numbers of OSD cases (excluding skin infections) for different occupations from the FROD in 2005-2016. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cod.13510DOI Listing

Tolerability of hair cleansing conditioners: a double-blind randomized, controlled trial designed to evaluate consumer complaints to the U.S. Food and Drug Administration.

Cutan Ocul Toxicol 2020 Jun 2;39(2):89-96. Epub 2020 Mar 2.

Park Nicollet Contact Dermatitis Clinic, Minneapolis, MN, USA.

Consumers have reported skin rash/irritation and hair loss/breakage with Wen by Chaz Dean Sweet Almond Mint Cleansing Conditioner (WCDSAMCC), however epidemiologic, toxicologic and clinical hair loss studies have not provided an explanation. Contact dermatitis has been hypothesized. To assess the tolerability of six products: WCDSAMCC, three other hair cleansing conditioners, and two controls [salicylic acid shampoo (SAS) and baby shampoo (BS)]. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/15569527.2020.1722154DOI Listing

Anogenital Dermatitis in Men Who Have Sex with Men.

Dermatol Clin 2020 Apr 5;38(2):227-232. Epub 2019 Dec 5.

Department of Dermatology, Kaiser Permanente, 3701 Broadway, Oakland, CA 94611, USA. Electronic address:

Evaluation of anogenital dermatitis requires a detailed history, including a sexual history. Men who have sex with men have different risk of certain infectious causes compared with men who have sex with women. Infectious causes of balanitis and anal dermatitis are easily treatable once identified. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.det.2019.10.007DOI Listing

A Hands-on Approach to Contact Dermatitis and Patch Testing.

J Allergy Clin Immunol Pract 2020 Jun 26;8(6):1883-1893. Epub 2020 Feb 26.

NYU Winthrop Hospital, Mineola, NY.

Contact dermatitis (CD) is a common skin condition caused by contact with an exogenous agent that elicits an inflammatory response. Although history and physical examination can be helpful in distinguishing between irritant CD and allergic CD (ACD), the gold standard for diagnosing ACD is patch testing. Although the actual patch test (PT) procedure and application is relatively straightforward, the decisions involving which allergens to use, interpretation of results, determination of relevant allergens, and subsequent patient management require more skill and expertise. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaip.2020.02.009DOI Listing

Hidden risks in toys: A systematic review of pediatric toy contact dermatitis.

Contact Dermatitis 2020 May 18;82(5):265-271. Epub 2020 Mar 18.

Department of Dermatology and Pediatrics, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Toys are a reflection of the compounds used frequently in manufacturing. Allergic contact dermatitis to potties, metal toys, and children's jewelry is well known, however, there is a broad range of skin risks in toys. With the objective to identify and publicize the associated risk of contact dermatitis in children's toys, we have searched the PubMed database from creation to September 9, 2019. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cod.13500DOI Listing

Dyshidrosiform Bullous Pemphigoid: Case Reports and Review.

Authors:
Philip R Cohen

Cureus 2020 Jan 11;12(1):e6630. Epub 2020 Jan 11.

Dermatology, San Diego Family Dermatology, San Diego, USA.

Bullous pemphigoid is an autoimmune blistering disorder that typically presents in elderly patients as pruritic tense subepidermal blisters on the lower trunk, axilla, and groin. It is caused by circulating and tissue-bound autoantibodies directed against bullous pemphigoid antigen 1 or bullous pemphigoid antigen 2 or both. Dyshidrosiform bullous pemphigoid is a rare variant of bullous pemphigoid, and it usually presents as itchy, potentially hemorrhagic, or purpuric blisters on the palms and/or soles of elderly individuals; subsequently, typical bullous lesions of bullous pemphigoid appear on other body sites. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7759/cureus.6630DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008730PMC
January 2020

12-year data on dermatologic cases in the Finnish Register of Occupational Diseases I: Distribution of different diagnoses and main causes of allergic contact dermatitis.

Contact Dermatitis 2020 Jun 26;82(6):337-342. Epub 2020 Feb 26.

Occupational Health Unit, Finnish Institute of Occupational Health (FIOH), Helsinki, Finland.

Background: Skin diseases are among the most common occupational diseases, but detailed analyses on their epidemiology, diagnoses, and causes are relatively scarce.

Objectives: To analyze data on skin disease in the Finnish Register of Occupational Diseases (FROD) for (1) different diagnoses and (2) main causes of allergic contact dermatitis (ACD).

Methods: We retrieved data on recognized cases with occupational skin disease (OSD) in the FROD from a 12-year-period 2005-2016 and used national official labor force data of the year 2012. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cod.13488DOI Listing

Neuronal hyperexcitability and astrocyte activation in spinal dorsal horn of a dermatitis mouse model with cutaneous hypersensitivity.

Neurosci Lett 2020 02 24;720:134784. Epub 2020 Jan 24.

Department of Applied Pharmacology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan. Electronic address:

Cleaning products such as soaps, shampoos, and detergents are comprised mainly of surfactants, agents known to cause dermatitis and cutaneous hypersensitivity characterized by itching, stinging, and burning of the skin and scalp. However, the mechanisms underlying surfactant-induced cutaneous hypersensitivity remain unclear. In the present study, we investigated the mechanisms of cutaneous hypersensitivity in mice treated with the detergent sodium dodecyl sulfate (SDS). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neulet.2020.134784DOI Listing
February 2020

[Contact allergy due to insulin pumps and glucose sensor systems].

Hautarzt 2020 Mar;71(3):205-210

Klinik und Poliklinik für Dermatologie und Allergologie, Ludwig-Maximilians-Universität , München, Deutschland.

The design and development of insulin pumps and various glucose sensor systems has an enormous impact on life quality of diabetic patients. Surveillance and therapy of diabetes has improved due to the new diabetic devices, which are affixed to the patients' skin for several days. Since their introduction, irritant and allergic contact dermatitis have been frequently reported. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00105-019-04533-xDOI Listing

Sensitizing fragrances in absorbent hygiene products.

Contact Dermatitis 2020 May 5;82(5):279-282. Epub 2020 Feb 5.

Medicines and Health Products, Sciensano, Brussels, Belgium.

Background: Allergenic fragrances are present in a wide range of products but they are not regulated in all industries to the same extent. In Europe, absorbent hygiene products (AHPs) are only covered by the general product safety directive and therefore fragrances can be used freely, whereas in cosmetics and toys the use of these ingredients is regulated.

Method: An analytical method was developed to evaluate the presence of 24 sensitizing fragrances in AHPs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cod.13472DOI Listing

Management of incontinence-associated dermatitis patients using a skin protectant in acute care: a case series.

J Wound Care 2020 Jan;29(1):18-26

Strategic Medical Writer, 3M Company, Medical & Clinical Affairs, St. Paul, US.

Objective: Incontinence-associated dermatitis (IAD) is a common type of irritant contact dermatitis. It is categorised by persistent erythema and can be associated with denudation and/or colonisation and infection. IAD is challenging to treat and affects 3. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.12968/jowc.2020.29.1.18DOI Listing
January 2020

CD44 expression in human skin: High expression in irritant and allergic contact dermatitis and moderate expression in psoriasis lesions in comparison with healthy controls.

Contact Dermatitis 2020 May 4;82(5):297-306. Epub 2020 Feb 4.

Department of Dermatovenereology, University Hospital Center Sestre Milosrdnice, Zagreb, Croatia.

Background: Previous research using animal models demonstrated that CD44 expression may contribute to directing inflammatory cells into skin lesions during inflammation development in allergic contact dermatitis (ACD).

Objectives: To examine CD44 expression in patients with ACD and irritant contact dermatitis (ICD), and to compare it to patients with psoriatic lesions and healthy controls' (HCs) skin.

Methods: This study included 200 patients comprising four groups of 50 each: ACD, ICD, psoriasis vulgaris, and HCs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cod.13463DOI Listing

Differences in itch and pain behaviors accompanying the irritant and allergic contact dermatitis produced by a contact allergen in mice.

Pain Rep 2019 Sep-Oct;4(5):e781. Epub 2019 Sep 11.

Department of Anesthesiology, Yale University School of Medicine, New Haven, CT, USA.

Introduction: Irritant contact dermatitis (ICD) and allergic contact dermatitis (ACD) are inflammatory skin diseases accompanied by itch and pain. Irritant contact dermatitis is caused by chemical irritants eliciting an innate immune response, whereas ACD is induced by haptens additionally activating an adaptive immune response: After initial exposure (sensitization) to the hapten, a subsequent challenge can lead to a delayed-type hypersensitivity reaction. But, the sensory and inflammatory effects of sensitization (ICD) vs challenge of ACD are insufficiently studied. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/PR9.0000000000000781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882579PMC
September 2019

Hand eczema treatment: Change behaviour with text messaging, a randomized trial.

Contact Dermatitis 2020 Mar 7;82(3):153-160. Epub 2020 Jan 7.

Medeniyet University Goztepe Training and Research Hospital, Department of Dermatology, Istanbul, Turkey.

Background: Irritant contact dermatitis is the most common type of hand eczema. Effective treatment usually involves avoidance of irritants and use of appropriate topical medication. In this study, the effectiveness of using text messaging addressing preventive behaviours and appropriate medication adherence was evaluated. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cod.13448DOI Listing

Irritant contact dermatitis due to Euphorbia trigona.

Contact Dermatitis 2020 Apr 1;82(4):234-235. Epub 2020 Jan 1.

Department of Dermatology, Faculty of Medicine, Ahi Evran University, Kırşehir, Turkey.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cod.13441DOI Listing

IL-6 Negatively Regulates IL-22R Expression on Epidermal Keratinocytes: Implications for Irritant Contact Dermatitis.

J Immunol Res 2019 29;2019:6276254. Epub 2019 Oct 29.

Department of Pharmaceutical Sciences, University of Oklahoma Health Sciences Center, 1110 N. Stonewall Avenue, Oklahoma City, OK 73117, USA.

Irritant Contact Dermatitis (ICD) is characterized by epidermal hyperplasia and inflammatory cytokine release. IL-6 has been shown to be involved in the pathogenesis of ICD; however, the involvement of the IL-22/IL-22R axis and its relation to IL-6 in the inflammatory response following irritant exposure are unknown. Using a chemical model of ICD, it was observed that mice with a keratinocyte-specific knockout of IL-6R (IL-6R) presented with increased inflammation and IL-22R and IL-22 protein expression relative to WT following irritant exposure, indicating that IL-6R deficiency in epidermal keratinocytes leads to the upregulation of IL-22R and its ligand during ICD. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2019/6276254DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6875369PMC