4,732 results match your criteria Contact Dermatitis Irritant


Using Patch Testing to Improve Therapeutic Outcome in the Treatment of Hand Eczema in Vietnamese Patients.

Open Access Maced J Med Sci 2019 Jan 23;7(2):204-207. Epub 2019 Jan 23.

University of Rome G. Marconi, Rome, Italy.

Background: Hand eczema is a common chronic and relapsing skin disease with various clinical features. Hand eczema aetiology can be allergic contact dermatitis (ACD), irritant contact dermatitis (ICD), atopic dermatitis (AD) and unknown or combination causes. If the causative agents are not detected treatment of hand eczema will be a failure. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3889/oamjms.2019.051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364736PMC
January 2019
1 Read

The Curious Cases of Burn by Fig Tree Leaves.

Indian J Dermatol 2019 Jan-Feb;64(1):71-73

Cardiac Anesthesia Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Phytophotodermatitis is a condition which is caused by contact with some plants containing furocoumarins. Furocoumarins in sap of fig tree are the main cause of its irritability when come in contact with the skin. The main symptoms are burning sensation and pain, itchy erythema, and edema, which usually begin 24 h after exposure. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/ijd.IJD_442_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340245PMC
February 2019
5 Reads

Bullous irritant contact dermatitis due to alcoholic extract from Juglans regia leaves.

Contact Dermatitis 2019 Feb 11. Epub 2019 Feb 11.

Section of Dermatology, Department of Medical Sciences, University of Ferrara, Italy.

Phytotherapeutic remedies can be responsible for allergic and irritant contact dermatitis and even chemical burns (1). We report a case of irritant contact dermatitis due to alcoholic extract from Juglans regia leaves. This article is protected by copyright. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cod.13240DOI Listing
February 2019
1 Read

Improvement of atopic dermatitis with dupilumab occurs equally well across different anatomic regions: data from phase 3 clinical trials.

Br J Dermatol 2019 Feb 4. Epub 2019 Feb 4.

Regeneron Pharmaceuticals, Inc, Tarrytown, NY, USA.

Moderate-to-severe atopic dermatitis (AD) can affect different parts of the body, and some adults have more localized AD, such as face and neck involvement. Compared with non-exposed areas, such as the trunk, exposed areas such as the face, neck, and hands could be more vulnerable to environmental allergens and irritants and can be more refractory to topical therapies. Local adverse effects of topical therapies are more likely to occur on the face and neck. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bjd.17703DOI Listing
February 2019
2 Reads

Filaggrin gene mutations in hand eczema patients in the Indian subcontinent: A prospective case-control study.

Contact Dermatitis 2019 Jan 25. Epub 2019 Jan 25.

Department of Dermatology, Venereology and Leprology, Chandigarh, India.

Background: There are no Indian studies on the association between filaggrin mutations and any dermatosis, including hand eczema.

Objectives: To determine the prevalence of filaggrin mutations in Indian hand eczema patients and examine associations between such mutation and any etiologic type of hand eczema.

Materials And Methods: A total of 163 patients and 86 controls were included. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cod.13233DOI Listing
January 2019
2 Reads

Erosio interdigitalis blastomycetica: A review of interdigital candidiasis.

Dermatol Online J 2018 Aug 15;24(8). Epub 2018 Aug 15.

Veterans Affairs Medical Center Brooklyn, New York SUNY Downstate, Department of Dermatology, Brooklyn, New York.

Erosio interdigitalis blastomycetica (EIB) is a Candida infection affecting the third web space, between the third and fourth fingers. In 1915, Gougerot and Goncea first described saccharomycetic organisms isolated from the hands and feet. Johannes Fabry later named it in 1917, well before the genus Candida was introduced in 1923. Read More

View Article

Download full-text PDF

Source
August 2018
1 Read

Asteraceae species as potential environmental factors of allergy.

Environ Sci Pollut Res Int 2019 Jan 21. Epub 2019 Jan 21.

Department of Botany, Subdepartment of Plants Biology, University of Life Sciences in Lublin, Akademicka 15, 20-950, Lublin, Poland.

The statistics from Europe and the USA have proven a high risk for skin diseases associated with plant contact. Therefore, plant-induced dermatitis is of increasing attention in dermatology. The focus of this paper was to present the current knowledge on aspects of contact allergy related to Asteraceae (Compositae) species. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11356-019-04146-wDOI Listing
January 2019
3 Reads

Eugenol as a Promising Molecule for the Treatment of Dermatitis: Antioxidant and Anti-inflammatory Activities and Its Nanoformulation.

Oxid Med Cell Longev 2018 11;2018:8194849. Epub 2018 Dec 11.

Pharmaceutical and Cosmetics Studies Center, Faculty of Pharmacy, Dentistry and Nursing, Federal University of Ceará, Fortaleza, Ceará, Brazil.

Contact dermatitis produces an inflammatory reaction primarily via stimulation of keratinocytes and cells of the immune system, which promote the release of cytokines, reactive oxygen species (ROS), and other chemical mediators. Eugenol (EUG, phenylpropanoid of essential oils) has attracted attention due to its anti-inflammatory properties, as well as antioxidant effect. On the other hand, it is volatile and insoluble and is a skin irritant. Read More

View Article

Download full-text PDF

Source
https://www.hindawi.com/journals/omcl/2018/8194849/
Publisher Site
http://dx.doi.org/10.1155/2018/8194849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311755PMC
February 2019
5 Reads

Patients with Negative Patch Tests: Retrospective Analysis of North American Contact Dermatitis Group (NACDG) Data 2001-2016.

J Am Acad Dermatol 2019 Jan 10. Epub 2019 Jan 10.

Division of Dermatology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.

Background: Little is known regarding characteristics of patients with negative patch tests (NPTs).

Objective: To characterize patients with NPTs.

Methods: Retrospective cross-sectional analysis of 34,822 patch tested patients. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S01909622193006
Publisher Site
http://dx.doi.org/10.1016/j.jaad.2018.12.062DOI Listing
January 2019
10 Reads

Anatomical Site Differences of Sodium Laurylsulphate Induced Irritation: randomised controlled trial.

Br J Dermatol 2019 Jan 13. Epub 2019 Jan 13.

Department of Pharmacy, University of Split School of Medicine, Šoltanska 2, 21000, Split, Croatia.

Background: Sodium laurylsulphate (SLS) induced contact dermatitis is a commonly used model for testing effects of different topical formulations. Volar forearms are preferred testing site by the guidelines, but other anatomical locations were used in previous research, especially upper back, as the clinically used site for testing different antigens.

Objectives: Aim of the present study was to investigate existence of anatomical variations of skin response to irritation and its' effects on response to treatment. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bjd.17633DOI Listing
January 2019
2 Reads

Cariniana domestica fruit peels present topical anti-inflammatory efficacy in a mouse model of skin inflammation.

Naunyn Schmiedebergs Arch Pharmacol 2019 Jan 7. Epub 2019 Jan 7.

Laboratory Neurotoxicity and Psychopharmacology, Graduate Program in Biological Sciences: Toxicological Biochemistry, Center of Natural and Exact Sciences, Federal University of Santa Maria, Av. Roraima 1000, Camobi, Santa Maria, RS, 97105-900, Brazil.

To investigate the topical anti-inflammatory activity of the crude extract of Cariniana domestica fruit peels (CdE), its dichloromethane, n-butanol, and ethyl acetate (EtAc) fractions, and steroids (β-sitosterol, lupeol, and stigmasterol) isolated from the EtAc fraction in models of irritant contact dermatitis (ICD) croton oil-induced in mice. We induced skin inflammation by single (acute; 1 mg/ear) and multiple (chronic; 0.4 mg/ear) croton oil application. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00210-018-1594-1DOI Listing
January 2019
2 Reads

Thermography: High sensitivity and specificity diagnosing contact dermatitis in patch testing.

Allergol Int 2018 Dec 28. Epub 2018 Dec 28.

Department of Dermatology, University Hospital Zurich, Zurich, Switzerland; Faculty of Medicine, University of Zurich, Zurich, Switzerland; Competence Center Personalized Medicine, University of Zurich and ETH Zurich, Zurich, Switzerland. Electronic address:

Background: Patch testing of contact allergens to diagnose allergic contact dermatitis (ACD) is a traditional, useful tool. The most important decision is the distinction between allergic and irritant reactions, as this has direct implications on diagnosis and management. Our objective was to evaluate a new method of non-contact infrared reading of patch tests. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.alit.2018.12.001DOI Listing
December 2018
3 Reads

Mechanics hands in patients with antisynthetase syndrome: 25 cases.

Ann Dermatol Venereol 2019 Jan 28;146(1):19-25. Epub 2018 Dec 28.

Dermatology clinic, université de Strasbourg, hôpitaux universitaires de Strasbourg, 1, place de l'Hôpital, 67000 Strasbourg, France.

Background: Antisynthetase antibodies (ASA) are directed against aminoacyl-tRNA-synthetases, ubiquitous enzymes of which eight types have hitherto been described. They are seen primarily in antisynthetase syndrome (ASS), in which diffuse interstitial lung disease is associated with inflammatory myopathy, joint involvement and cutaneous signs, in particular mechanic's hands. The aim of this study was to determine the prevalence and semiological characteristics of cutaneous involvement in patients presenting ASA. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.annder.2018.11.010DOI Listing
January 2019
2 Reads

Phytodermatitis in East and southeast of Turkey: A prospective study.

Authors:
Isa An Murat Ozturk

Cutan Ocul Toxicol 2018 Dec 26:1-6. Epub 2018 Dec 26.

b Department of Dermatology , Health Sciences Universty Van Training and Research Hospital , Van , Turkey.

Objective: Some plants may cause cutaneous side effects called phytodermatitis due to skin contact. Plants that cause phytodermatitis vary according to countries and regions. The aim of this study was to examine the phytodermatitis cases seen in Turkey's east and southeast and compare them with phytodermatitis cases seen previously in the literature in these provinces and to revise the literature. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/15569527.2018.1561711DOI Listing
December 2018
3 Reads

"Slime" dermatitis, a fad-associated chronic hand dermatitis.

Pediatr Dermatol 2019 Jan 16;36(1):e39-e40. Epub 2018 Dec 16.

Division of Dermatology, Children's National Health Center, Washington, District of Columbia.

"Slime" is the colloquial name for a non-Newtonian viscoelastic putty-like substance that is currently a popular plaything among pre-teens and adolescents. Several ingredients in homemade slime recipes may cause irritant or allergic contact dermatitis. We report two children who developed slime-associated chronic hand dermatitis, more prominently on their dominant hand. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/pde.13729DOI Listing
January 2019
2 Reads

Occupational contact dermatitis caused by isopropanol-containing disinfectant based on a genetic defect.

Contact Dermatitis 2018 Dec 12. Epub 2018 Dec 12.

Department of Dermatology and Venerology, Medical University of Graz, Graz, Austria.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cod.13197DOI Listing
December 2018
4 Reads

Topical anti-inflammatory and anti-oxidative effects of porcine placenta extracts on 2,4-dinitrochlorobenzene-induced contact dermatitis.

BMC Complement Altern Med 2018 Dec 12;18(1):331. Epub 2018 Dec 12.

Department of Biomedical Science and Engineering, Konkuk Institute of Technology, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul, 05029, South Korea.

Background: The placenta is a reservoir enriched with growth factors, hormones, cytokines and minerals. While several beneficial effects of placenta extracts on wound healing, anti-aging and anti-inflammatory responses have been reported, relatively limited mechanistic exploration has been conducted to date. Here, we provide compelling evidence of anti-inflammatory and anti-oxidative activities of porcine placenta extracts (PPE) against contact dermatitis in vivo. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12906-018-2396-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291973PMC
December 2018
1 Read

Interdisciplinary and multiprofessional outpatient secondary individual prevention of work-related skin diseases in the metalworking industry: 1-year follow-up of a patient cohort.

BMC Dermatol 2018 Dec 12;18(1):12. Epub 2018 Dec 12.

Department of Dermatology, Klinikum Dortmund gGmbH, Beurhausstr. 40, 44137, Dortmund, Germany.

Background: In Germany, work-related skin diseases are predominant within the spectrum of reported occupational diseases. Metal workers are among the high-risk professions. Offering effective prevention programs to affected patients is of utmost importance to avoid deterioration of the disease and job loss. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12895-018-0080-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292163PMC
December 2018
1 Read

Associations Between Immune Phenotype and Inflammation in Murine Models of Irritant Contact Dermatitis.

Toxicol Sci 2018 Dec 4. Epub 2018 Dec 4.

Pharmaceutical Sciences Department, University of Oklahoma Health Science Center, 110 N. Stonewall, Oklahoma City, OK.

Irritant contact dermatitis (ICD), the most common occupational cutaneous illness, is an acute inflammatory response caused by topical irritant exposure. Multiple factors are associated with the manifestation and severity of ICD and contribute to the lack of effective prophylactic and treatment strategies. To determine the pathomechanism of ICD caused by the irritants, benzalkonium chloride (BKC) and JP-8 jet fuel, two mouse strains, C57BL/6 and Balb/c, were assessed due to their differential immune predispositions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/toxsci/kfy289DOI Listing
December 2018
7 Reads

Contact dermatitis and sensitization in professional musicians.

Contact Dermatitis 2018 Nov 29. Epub 2018 Nov 29.

Department of Dermatology and Allergology, Allergy-Centre-Charité, Charité - Universitätsmedizin Berlin, Berlin, Germany.

Background: Professional musicians have prolonged and intense physical contact with their instruments. This can lead to occupational skin diseases, particularly irritant and allergic contact dermatitis.

Objectives: To assess the skin diseases and sensitization patterns common among professional musicians. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cod.13191DOI Listing
November 2018
3 Reads

Characteristics of persistent diaper dermatitis in children with food allergy.

Pediatr Dermatol 2018 Nov 28. Epub 2018 Nov 28.

Department of Pediatrics, Medical Faculty, Inonu University, Malatya, Turkey.

Background/objectives: Diaper dermatitis is often caused by irritant contact occurring beneath the diaper of an infant, and it is aggravated by factors such as dampness, friction, urea, and feces. Food-allergic patients are known to exhibit various skin lesions ranging from urticaria to eczema. This study aims to determine the relationship between persistent diaper dermatitis and food allergy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/pde.13733DOI Listing
November 2018
2 Reads

Evaluation of the profile of inflammatory cytokines, through immunohistochemistry, in the skin of patients with allergic contact dermatitis to nickel in the acute and chronic phases.

An Bras Dermatol 2018 Nov/Dec;93(6):829-835

Department of Dermatology, Faculdade de Medicina, Universidade de São Paulo, São Paulo (SP), Brazil.

Background: Allergic contact dermatitis to ion nickel (Ni+2) is an inflammatory dermatosis, common in industrialized countries. It involves the activation of nickel-specific T-cells, followed by proliferation and induction of a mixed profile of both proinflammatory and regulatory cytokines, suggesting that several T-cell subtypes (helper - Th and cytotoxic - Tc) are involved. A broader understanding of the cytokine profile may lead to new therapeutic approaches. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1590/abd1806-4841.20187126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256231PMC
February 2019
2 Reads

Contact Dermatitis: Emerging Trends.

Dermatol Clin 2019 Jan 1;37(1):21-28. Epub 2018 Nov 1.

The Ronald O. Perelman Department of Dermatology, New York University School of Medicine, 240 East 38th Street, Floor 11, New York, NY 10016, USA.

The field of contact dermatitis is constantly evolving. Trends in irritant and allergic contact dermatitis are shaped by the introduction of new chemicals, revival of older allergens, industrial practices, and consumer behaviors. This article discusses the most noteworthy trends within the field, organized by allergen category, with particular attention to newer and/or controversial allergens. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.det.2018.07.005DOI Listing
January 2019
3 Reads

Tabernaemontana catharinensis leaves exhibit topical anti-inflammatory activity without causing toxicity.

J Ethnopharmacol 2019 Mar 13;231:205-216. Epub 2018 Nov 13.

Laboratory Neurotoxicity and Psychopharmacology, Graduate Program in Biological Sciences: Toxicological Biochemistry, Center of Natural and Exact Sciences, Federal University of Santa Maria, Santa Maria, RS, Brazil. Electronic address:

Background: Tabernaemontana catharinensis, popularly known as snake skin, has been empirically used as an anti-inflammatory to treat cutaneous skin disorders. However, no study proves its effectiveness as a topical anti-inflammatory.

Study Design: We investigated the topical anti-inflammatory effect of T. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S03788741183329
Publisher Site
http://dx.doi.org/10.1016/j.jep.2018.11.021DOI Listing
March 2019
14 Reads

Differential Diagnosis of Cheilitis - How to Classify Cheilitis?

Acta Clin Croat 2018 Jun;57(2):342-351

Department of Dermatovenereology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia.

Although cheilitis as a term describing lip inflammation has been identified and recognized for a long time, until now there have been no clear recommendations for its work-up and classification. The disease may appear as an isolated condition or as part of certain systemic diseases/conditions (such as anemia due to vitamin B12 or iron deficiency) or local infections (e.g. Read More

View Article

Download full-text PDF

Source
https://hrcak.srce.hr/index.php?show=clanak&id_clanak_je
Publisher Site
http://dx.doi.org/10.20471/acc.2018.57.02.16DOI Listing
June 2018
16 Reads

A review of non-glove personal protective equipment-related occupational dermatoses reported to EPIDERM between 1993 and 2013.

Contact Dermatitis 2018 Nov 14. Epub 2018 Nov 14.

Centre for Occupational and Environmental Health, University of Manchester, Oxford Road, Manchester, UK.

Background: Personal protective equipment (PPE) is defined as equipment that protects the wearer's body against health/safety risks at work. Gloves cause many dermatoses. Non-glove PPE constitutes a wide array of garments. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/cod.13177
Publisher Site
http://dx.doi.org/10.1111/cod.13177DOI Listing
November 2018
5 Reads

Contact dermatitis and atopic dermatitis- Two tales, an interwoven story.

G Ital Dermatol Venereol 2018 Nov 9. Epub 2018 Nov 9.

Department of Dermatology, Loma Linda University, Loma Linda, CA, USA -

Atopic dermatitis is a multifactorial disease that can concomitantly occur with irritant and allergic contact dermatitis. The colloquial use of atopic dermatitis and eczema interchangeably has created confusion among patients and providers alike. Atopic skin is a complex entity that involves a defective barrier and biome, an aberrant immune response, and abnormal neural activation, while eczema is a generalized term denoting a particular appearance common to multiple diagnoses including atopic dermatitis and contact dermatitis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.23736/S0392-0488.18.06236-3DOI Listing
November 2018
1 Read

Evaluating the effect of electronic monitoring and feedback on hand cream use in healthcare workers: Healthy Hands Project.

Contact Dermatitis 2019 Jan 13;80(1):26-34. Epub 2018 Nov 13.

Coronel Institute of Occupational Health, Amsterdam Public Health Research Institute, Amsterdam UMC, Amsterdam, The Netherlands.

Background: Healthcare workers (HCWs) are at high risk of developing hand dermatitis (HD). Current guidelines on HD prevention recommend the use of emollients; however, in practice, adherence is poor.

Objective: To assess whether the provision of creams, electronic monitoring and feedback on cream consumption can improve skin care in HCWs. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/cod.13148
Publisher Site
http://dx.doi.org/10.1111/cod.13148DOI Listing
January 2019
6 Reads

Trends in Patch Testing With the Mayo Clinic Standard Series, 2011-2015.

Dermatitis 2018 Nov/Dec;29(6):310-315

Department of Dermatology and.

Background: Patch testing to a standard (baseline) series of allergens is the screening tool used to identify culprit allergens in patients with contact dermatitis. The allergens and concentrations used in a standard series are constantly evolving to be most relevant to the patients being patch tested.

Objective: The aim of this study was to analyze the 2011-2015 patch test results of the Mayo Clinic standard series. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/DER.0000000000000411DOI Listing
November 2018
12 Reads

Impact of water exposure on skin barrier permeability and ultrastructure.

Contact Dermatitis 2018 Nov 12. Epub 2018 Nov 12.

Biological Science Research, Kao Corporation, Tochigi, Japan.

Background: Skin occlusion caused by the use of diapers or sanitary napkins often results in irritant contact dermatitis. Furthermore, prolonged occlusion and exposure to body fluids are known to increase skin hydration and permeability, thus leading to irritant contact dermatitis.

Objective: To investigate the effects of water exposure on the skin and its barrier functions, in order to obtain more insights into the mechanisms of irritant contact dermatitis. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/cod.13174
Publisher Site
http://dx.doi.org/10.1111/cod.13174DOI Listing
November 2018
9 Reads

Tabernaemontana catharinensis leaves effectively reduce the irritant contact dermatitis by glucocorticoid receptor-dependent pathway in mice.

Biomed Pharmacother 2019 Jan 4;109:646-657. Epub 2018 Nov 4.

Laboratory Neurotoxicity and Psychopharmacology, Graduate Program in Biological Sciences: Toxicological Biochemistry, Center of Natural and Exact Sciences, Federal University of Santa Maria, Santa Maria, RS, Brazil. Electronic address:

Ethnopharmacological Relevance: Tabernaemontana catharinensis, popularly known as snakeskin, is used in traditional medicine to treat skin inflammatory disorders. To confirm the topical anti-inflammatory effect of T. catharinensis leaves, we evaluated the therapeutic effect of crude extract (TcE) and its different fractions on irritant contact dermatitis model in mice and verified its anti-inflammatory action mechanism. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S07533322183629
Publisher Site
http://dx.doi.org/10.1016/j.biopha.2018.10.132DOI Listing
January 2019
11 Reads

Gerontodermatology: the fragility of the epidermis in older adults.

J Eur Acad Dermatol Venereol 2018 Nov;32 Suppl 4:1-20

Pharmacology Division, Pierre Fabre Dermo-Cosmétique, Toulouse, France.

The proportion of adults over 60 years of age is rapidly increasing and is estimated to reach approximately one-sixth of the global population by 2030. An ageing population is a real challenge for healthcare resources, including dermatologists and geriatricians, as age-related changes in skin integrity and barrier function make older adults more susceptible to developing skin pathologies such as pruritus, dermatitis and infections. Fragile skin arises from several interlinked causes, including age-related changes in skin barrier integrity, previous and current lifestyle choices, skin pathologies and medical interventions. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/jdv.15253
Publisher Site
http://dx.doi.org/10.1111/jdv.15253DOI Listing
November 2018
14 Reads

Atypical Skin Inflammation in a 2.5-Year-Old Girl With Atopic Dermatitis.

J Investig Allergol Clin Immunol 2018 Oct;28(5):336-338

Department of Pediatrics, Allergology and Gastroenterology Collegium Medicum Bydgoszcz, Nicolaus Copernicus University of Torun, Poland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18176/jiaci.0276DOI Listing
October 2018
2 Reads

Contact Dermatitis Caused by Dermabond Advanced Use.

Plast Reconstr Surg Glob Open 2018 Sep 14;6(9):e1841. Epub 2018 Sep 14.

Department of Plastic Surgery, Jichi Medical University, Tochigi, Japan.

Background: Dermabond Advanced (DBA) has been widely used globally; however, severe contact dermatitis (CD) can be a serious adverse effect of DBA use. In this study, we investigated the characterization and incidence rate of CD after using DBA and the safe use of DBA.

Methods: One hundred consecutive patients who underwent skin closure with DBA were investigated. Read More

View Article

Download full-text PDF

Source
http://Insights.ovid.com/crossref?an=01720096-201809000-0001
Publisher Site
http://dx.doi.org/10.1097/GOX.0000000000001841DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191225PMC
September 2018
13 Reads

Nasturtium officinale R. Br. effectively reduces the skin inflammation induced by croton oil via glucocorticoid receptor-dependent and NF-κB pathways without causing toxicological effects in mice.

J Ethnopharmacol 2019 Jan 17;229:190-204. Epub 2018 Oct 17.

Laboratory Neurotoxicity and Psychopharmacology, Graduate Program in Biological Sciences: Toxicological Biochemistry, Center of Natural and Exact Sciences, Federal University of Santa Maria, Santa Maria, RS, Brazil; Graduate Program in Biological Sciences: Toxicological Biochemistry, Center of Natural and Exact Sciences, Federal University of Santa Maria, Santa Maria, RS, Brazil. Electronic address:

Ethnopharmacological Relevance: Inflammatory skin diseases treatments currently used cause adverse effects. Nasturtium officinale (watercress) is used popularly as an anti-inflammatory. However, until now, no study proved its effectiveness as a topical treatment to inflammatory skin diseases. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jep.2018.10.011DOI Listing
January 2019
15 Reads

How to improve the assessment of the impact of occupational diseases at a national level? The Netherlands as an example.

Occup Environ Med 2019 Jan 8;76(1):30-32. Epub 2018 Oct 8.

Amsterdam UMC, University of Amsterdam, Department: Coronel Institute of Occupational Health, Netherlands Center for Occupational Diseases, Amsterdam Public Health research institute, Amsterdam, The Netherlands.

Objective: To explore the impact of occupational diseases (ODs) through estimations of population attributable fractions (PAFs) in a national context.

Methods: PAFs were calculated for eight prevalent ODs using existing data on the prevalence of exposure to risk factors at work and the strength of their association with diseases based on systematic reviews. Six systematic reviews with meta-analyses and two overview papers were selected. Read More

View Article

Download full-text PDF

Source
http://oem.bmj.com/lookup/doi/10.1136/oemed-2018-105387
Publisher Site
http://dx.doi.org/10.1136/oemed-2018-105387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327862PMC
January 2019
13 Reads

Irritant Contact Dermatitis.

Clin Rev Allergy Immunol 2019 Feb;56(1):99-109

State University of New York, Stony Brook, NY, USA.

Contact dermatitis accounts for 95% of occupational skin disorders. Irritant contact dermatitis (ICD) is often caused by cumulative exposure to weak irritants, accounting for 80% of all cases of contact dermatitis. ICD can co-exist with atopic dermatitis (AD) and allergic contact dermatitis (ACD). Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s12016-018-8713-0
Publisher Site
http://dx.doi.org/10.1007/s12016-018-8713-0DOI Listing
February 2019
17 Reads

Recurrent Granuloma Gluteale Infantum Secondary to Fecal Overflow Incontinence.

Case Rep Dermatol 2018 May-Aug;10(2):203-207. Epub 2018 Aug 23.

University of North Texas Health Science Center, Fort Worth, Texas, USA.

Granuloma gluteale infantum is a rare pediatric dermatological disorder of uncertain etiology. Suggested causes include fluorinated corticosteroids, , and irritant contact dermatitis. We present the case of a 3-year-old boy with recurrent episodes of granuloma gluteale infantum which resolved with treatment of his fecal overflow incontinence. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000492270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167654PMC
August 2018
6 Reads

Defensive Effects of a Unique Polysaccharide, Sacran, to Protect Keratinocytes against Extracellular Stimuli and Its Possible Mechanism of Action.

Biol Pharm Bull 2018 ;41(10):1554-1560

Tokyo University of Technology Graduate School, Department of Bionics.

Sacran, a polysaccharide isolated from the alga Aphanothece sacrum (Suizenji-nori), has unique physical and physiological characteristics. In a previous study, we reported that sacran improves skin conditions in individuals who suffer from atopic dermatitis (AD), focusing on its trapping function against extrinsic stimuli compared with hyaluronic acid (HA). First, we examined the penetration of sacran through stratum corneum (SC) with an impaired barrier function using immature reconstructed human epidermal equivalents. Read More

View Article

Download full-text PDF

Source
https://www.jstage.jst.go.jp/article/bpb/41/10/41_b18-00194/
Publisher Site
http://dx.doi.org/10.1248/bpb.b18-00194DOI Listing
January 2019
2 Reads

Patch Testing Pearls.

Clin Rev Allergy Immunol 2019 Feb;56(1):110-118

Dermatology Physicians, Inc., 360 Plaza Drive Suite C, Columbus, IN, 47201, USA.

Dermatitis is one of the most common illnesses encountered by healthcare providers and the causes are numerous. Contact dermatitis is the form of dermatitis resulting from contact with the environment, and it may be either irritant or allergic in nature. Patch testing has been the gold standard for diagnosis of allergic contact dermatitis since its formal description over 100 years ago by Jadassohn. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12016-018-8715-yDOI Listing
February 2019
10 Reads

Skin irritation and sensitization potential of oxidative hair dye substances evaluated with in vitro, in chemico and in silico test methods.

Food Chem Toxicol 2018 Nov 11;121:360-366. Epub 2018 Sep 11.

College of Pharmacy, Ewha Womans University, Seoul, 03760, Republic of Korea. Electronic address:

Permanent oxidative hair dyes are widely used but their toxicity is not well-established. Here we aimed to evaluate the skin sensitization and irritation of nine hair dye substances (MAP, MRP-N, RS, PAOX, 2,4-DAPE, 2,6-PYR, PPD, Grey HED and PM) permitted for use in EU and Korea, using in vitro and in chemico and in silico test methods. Skin sensitization was evaluated by the KeratinoSens™ assay, Direct Peptide Reactivity Assay (DPRA) and DEREK. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.fct.2018.09.017DOI Listing
November 2018
2 Reads

Transcriptional profiling of irritant contact dermatitis (ICD) in a mouse model identifies specific patterns of gene expression and immune-regulation.

Toxicology 2018 Dec 29;410:1-9. Epub 2018 Aug 29.

Department of Pharmaceutical Science, University of Oklahoma Health Science Center, 1110 N. Stonewall, Oklahoma City, OK, 73117, United States. Electronic address:

Background: Irritant contact dermatitis (ICD) is a cutaneous inflammatory response to a variety of triggers that requires no sensitization and accounts for up to 80% of occupational dermatitis cases. IL-6 has been alternately associated with both allergic and irritant dermatitis and is closely linked to skin wound healing, therefore making it an ideal candidate to investigate in the mechanism of ICD.

Results: Despite being a well-known pro-inflammatory cytokine, IL-6 deficient (IL-6KO) mice show much more severe ICD than controls. Read More

View Article

Download full-text PDF

Source
https://www.researchgate.net/publication/327294753_Transcrip
Web Search
https://linkinghub.elsevier.com/retrieve/pii/S0300483X183029
Publisher Site
http://dx.doi.org/10.1016/j.tox.2018.08.014DOI Listing
December 2018
23 Reads

Occupational and Hand Dermatitis: a Practical Approach.

Clin Rev Allergy Immunol 2019 Feb;56(1):60-71

University of North Carolina School of Medicine, 321 S Columbia Street, Chapel Hill, NC, 27516, USA.

Occupational skin disease is common. It affects workers more often than reported. Contact dermatitis, both irritant and allergic, accounts for the majority of occupational skin diagnoses. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s12016-018-8706-z
Publisher Site
http://dx.doi.org/10.1007/s12016-018-8706-zDOI Listing
February 2019
16 Reads

A slime of the times: Two cases of acute irritant contact dermatitis from homemade slime.

Pediatr Dermatol 2019 Jan 28;36(1):139-141. Epub 2018 Aug 28.

Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

We describe two cases of acute-onset erythema, peeling, and pruritus or tenderness isolated to the palmar surface of the hands. A detailed exposure history revealed significant periods of contact with homemade slime; given the clinical findings and timing of exposure, acute contact dermatitis of the hands was suspected. Symptoms and clinical findings resolved after avoidance of the suspected causative contactants. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/pde.13617DOI Listing
January 2019
14 Reads

A recalcitrant case of Jacquet erosive diaper dermatitis after surgery for Hirschsprung disease in a boy with Waardenburg-Shah syndrome.

Dermatol Online J 2018 Jun 15;24(6). Epub 2018 Jun 15.

Department of Dermatology and Venereology, Istanbul Faculty of Medicine, Istanbul University, Istanbul.

We herein present a 4 year-old boy with Waardenburg-Shah syndrome who developed Jacquet erosive diaper dermatitis following a total colectomy and ileoanal anastomosis procedure for Hirschsprung disease. The diagnosis was made according to history and typical clinical findings. Complete resolution of the recalcitrant lesions after an ileostomy procedure supported the diagnosis. Read More

View Article

Download full-text PDF

Source
June 2018
4 Reads

Comparison of the skin sensitization potential of 3 red and 2 black tattoo inks using interleukin-18 as a biomarker in a reconstructed human skin model.

Contact Dermatitis 2018 Dec 22;79(6):336-345. Epub 2018 Aug 22.

Department of Molecular Cell Biology and Immunology, VU University Medical Centre, Amsterdam UMC, Amsterdam, The Netherlands.

Background: During the last decade, the number of people with ≥1 tattoo has increased noticeably within the European population. Despite this, limited safety information is available for tattoo inks.

Objectives: To test the skin sensitization potential of 5 tattoo inks in vitro by using reconstructed human skin (RHS) and the contact sensitization biomarker interleukin (IL)-18. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cod.13092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282746PMC
December 2018
4 Reads

Using therapeutic ultrasound to promote irritated skin recovery after surfactant-induced barrier disruption.

Ultrasonics 2019 Jan 13;91:206-212. Epub 2018 Aug 13.

Department of Physical Therapy, Chung Shan Medical University, and Physical Therapy Room, Chung Shan Medical University Hospital, Taichung, Taiwan. Electronic address:

Background: Surfactant-induced skin barrier disruption can enhance blood flow and water content in the superficial skin. The effect of therapeutic ultrasound on accelerating the recovery of superficial skin after skin barrier disruption has seldom been studied.

Objective: To understand the effects of therapeutic ultrasound on barrier recovery, we used the sodium lauryl sulfate irritation model and treatment with ultrasound intervention. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ultras.2018.08.007DOI Listing
January 2019
14 Reads

Distribution of childhood skin diseases according to age and gender, a single institution experience.

Turk Pediatri Ars 2018 Jun 1;53(2):105-112. Epub 2018 Jun 1.

Department of Dermatology, Erzincan University Mengücek Gazi Training and Research Hospital, Erzincan, Turkey.

Aim: Studies on pediatric skin diseases in Turkey are not yet sufficient. It was aimed to characterize the prevalence of skin diseases, age and gender distribution in children living in the Erzincan region.

Material And Methods: 10,115 children aged 0-16 years who reached to our outpatient clinic between 01. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5152/TurkPediatriArs.2018.6431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089785PMC
June 2018
3 Reads

Contact allergy in Danish children: Current trends.

Contact Dermatitis 2018 Nov 9;79(5):295-302. Epub 2018 Aug 9.

National Allergy Research Centre, Department of Dermatology and Allergy, University of Copenhagen, Herlev and Gentofte Hospital, Gentofte, Denmark.

Background: Contact allergy is common in children, but may be underdiagnosed. Importantly, the clinical relevance of specific allergies is subject to constant change, and it is therefore important to continuously monitor the trends and changes of contact allergies in the paediatric population.

Objectives: To identify possible changes in contact allergy and allergic contact dermatitis among Danish children referred for patch testing. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/cod.13079
Publisher Site
http://dx.doi.org/10.1111/cod.13079DOI Listing
November 2018
20 Reads