4,756 results match your criteria Contact Dermatitis Irritant


The impact of recent advances in lipidomics and redox lipidomics on dermatological research.

Free Radic Biol Med 2019 Apr 17. Epub 2019 Apr 17.

Department of Dermatology, Medical University of Vienna, Austria; Christian Doppler Laboratory for the Biotechnology of Skin Aging, Vienna, Austria.

Dermatological research is a major beneficiary of the rapidly developing advances in lipid analytic technology and of bioinformatic tools which help to decipher and interpret the accumulating big lipid data. At its interface with the environment, the epidermis develops a blend of lipids that constitutes the epidermal lipid barrier, essential for the protection from water loss and entry of dangerous noxae. Apart from their structural role in the barrier, novel intra- and inter-cellular signaling functions of lipids and their oxidation products have been uncovered in most cutaneous cell types over the last decades, and the discovery rate has been boosted by the advent of high resolution and -throughput mass spectrometric techniques. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08915849193015
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http://dx.doi.org/10.1016/j.freeradbiomed.2019.04.019DOI Listing
April 2019
1 Read

Airborne allergic contact dermatitis caused by Machaerium scleroxylon: confirmation by in vivo and in vitro tests.

Contact Dermatitis 2019 Apr 8. Epub 2019 Apr 8.

Section of Clinical, Allergological and Venereological Dermatology, Department of Medicine, University of Perugia, Italy.

Airborne agents can cause several skin reactions in occupational and less frequently in non-occupational settings, due to their strong irritant and/or sensitizing properties (1). Airborne allergic contact dermatitis is frequently caused by woods (2), above all tropical and subtropical woods containing many strong contact allergens, such as quinones (3). A case of airborne allergic contact dermatitis caused by Machaerium (M. Read More

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http://dx.doi.org/10.1111/cod.13287DOI Listing
April 2019
10 Reads

Evaluation of the Impact of 2 Disposable Diapers in the "Natural" Diaper Category on Diapered Skin Condition.

Clin Pediatr (Phila) 2019 Apr 9:9922819841136. Epub 2019 Apr 9.

1 The Procter & Gamble Company, Cincinnati, OH, USA.

The demand for natural infant care products, including diapers, has increased. However, few disposable diapers have been able to provide the performance caregivers desire while also incorporating ingredients consistent with the "natural" category. In an examiner-blinded clinical study, the performance of a new cotton-enhanced diaper with high-performance materials was compared with an existing natural diaper offering. Read More

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http://journals.sagepub.com/doi/10.1177/0009922819841136
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http://dx.doi.org/10.1177/0009922819841136DOI Listing
April 2019
7 Reads

Skin Biophysical Parameters and Patch Test Results in People Predisposing to Xiaotong Tiegao Induced Irritant Contact Dermatitis.

Evid Based Complement Alternat Med 2019 24;2019:8612561. Epub 2019 Feb 24.

Department of Dermatology, Beijing Friendship Hospital, Capital Medical University, 95 Yong An Road, Xi Cheng District, Beijing 100050, China.

Background: Xiaotong Tiegao (XTT) is an ancient topical Tibetan medicine plaster which is widely used in China. Irritant contact dermatitis (ICD) caused by XTT is very common. It is still unclear why some people are more prone to develop ICD. Read More

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http://dx.doi.org/10.1155/2019/8612561DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409027PMC
February 2019
2 Reads

Allergic contact dermatitis to phenylbenzimidazole sulfonic acid included in a sunscreen.

Contact Dermatitis 2019 Mar 20. Epub 2019 Mar 20.

Department of Dermatology, Hospital Universitario del Henares, Coslada (Madrid), Spain.

Adverse reactions to sunscreens include allergic, irritant, phototoxic and photoallergic contact dermatitis (1). Allergic and photoallergic contact dermatitis to sunscreen may be caused by chemical ultraviolet (UV) absorbers, preservatives, perfumes, and other constituents. Photoallergic contact dermatitis reaction to UV absorbers is not common, and more frequent than allergic contact dermatitis. Read More

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http://dx.doi.org/10.1111/cod.13271DOI Listing
March 2019
2 Reads

Variable impact of dupilumab on patch testing results and allergic contact dermatitis in adults with atopic dermatitis.

J Am Acad Dermatol 2019 Mar 15. Epub 2019 Mar 15.

Department of Dermatology, Preventive Medicine and Medical Social Sciences, Feinberg School of Medicine at Northwestern University, Chicago, IL; Northwestern Medicine Multidisciplinary Eczema Center, Chicago, IL. Electronic address:

Background: Previous case reports/series suggested that dupilumab may be an effective treatment for allergic contact dermatitis (ACD). Little is known about the impact of dupilumab on patch test results and comorbid ACD in patients with atopic dermatitis (AD).

Objective: Determine the impact of dupilumab on patch testing results and improvement of ACD in AD patients. Read More

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http://dx.doi.org/10.1016/j.jaad.2019.03.020DOI Listing
March 2019
2 Reads

"Slime" contact dermatitis: Case report and review of relevant allergens.

Pediatr Dermatol 2019 Mar 13. Epub 2019 Mar 13.

Department of Dermatology, Massachusetts General Hospital, Boston, Massachusetts.

Homemade "slime" is currently a popular childhood hobby that can cause allergic and irritant contact dermatitis. We describe a case of hand dermatitis due to homemade "slime" with a positive patch test to methylchloroisothiazolinone (MCI)/methylisothiazolinone (MI) and MI. The most common potential allergens in "slime" collected from a review of "slime" recipes found on the Internet are reviewed. Read More

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http://dx.doi.org/10.1111/pde.13792DOI Listing
March 2019
1 Read

Botulinum neurotoxin A is an effective treatment for irritant dermatitis caused by ostomy leaks in patients with retractile stomas.

Br J Dermatol 2019 Mar 6. Epub 2019 Mar 6.

Department of Dermatology, York Teaching Hospital Foundation Trust, York, YO31 8HE, United Kingdom.

Inflammatory or infectious conditions affecting the skin around a stoma occur in up to 73% of ostomates and can be associated with significant morbidity. Peristomal skin complications include dermatitis resulting from mechanical trauma, ICD, allergic contact dermatitis, infections and pyoderma gangrenosum. Peristomal dermatitis is most often caused by leakage of stool or urine that is irritant to the skin. Read More

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http://dx.doi.org/10.1111/bjd.17856DOI Listing
March 2019
1 Read

Contact Dermatitis in Northeast Italy Mechanics (1996-2016).

Dermatitis 2019 Mar/Apr;30(2):150-154

From the Clinical Unit of Occupational Medicine, University of Trieste, Italy.

Background: Mechanics are at higher risk to develop occupational skin diseases from exposure to irritants, oils, greases, preservatives, and metals.

Aims: The aim of the study was to investigate contact dermatitis in mechanics who underwent patch test in Northeastern Italy and compare them with white-collar workers (WCW).

Subjects And Methods: From 1996 to 2016, 27,381 patients with suspected allergic contact dermatitis were patch tested in Northeastern Italy; in this group, 1270 mechanics were studied. Read More

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http://dx.doi.org/10.1097/DER.0000000000000456DOI Listing
March 2019
4 Reads

Euphorbia myrsinites Sap-Induced Phytodermatitis: A Prototype of Irritant Contact Dermatitis?

Dermatitis 2019 Mar/Apr;30(2):155-161

From the Department of Dermatology, Medical University of Vienna, Austria.

Background: A hallmark of Euphorbia myrsinites (EM), a member of the widespread perennial Euphorbia species, is the extrusion of a poisonous, latex-like sap irritant to the skin and eye after contact. The exact mechanisms underlying these effects have not been unraveled so far.

Objectives: The aims of the study were to allocate EM sap-induced phytodermatitis to irritant or allergic contact dermatitis (ACD) and to investigate mechanism(s) causing keratinocyte damage. Read More

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http://dx.doi.org/10.1097/DER.0000000000000454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420095PMC
March 2020
4 Reads

Fiberglass dermatitis: clinical presentations, prevention, and treatment - a review of literatures.

Int J Dermatol 2019 Feb 28. Epub 2019 Feb 28.

Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.

Fiberglass dermatitis is a common form of occupational irritant contact dermatitis. Individuals experience a negative reaction to fiberglass fragments because of mechanical irritation. This review comprehensively analyzes the information in the existing literature on fiberglass dermatitis. Read More

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http://dx.doi.org/10.1111/ijd.14407DOI Listing
February 2019
2 Reads

The THP-1 cell toolbox: a new concept integrating the key events of skin sensitization.

Arch Toxicol 2019 Feb 26. Epub 2019 Feb 26.

UMR996-Inflammation, Chemokines and Immunopathology, INSERM, Univ Paris-Sud, Université Paris-Saclay, 92296, Châtenay-Malabry, France.

According to the current scientific consensus, one in vitro test is insufficient to cover the key events (KE) defined by the adverse outcome pathway (AOP) for skin sensitization. To address this issue we combined different end points in the same cell line to cover all KEs defined by the skin sensitization AOP. Since dendritic cells (DC) play a key role in the sensitization phase leading to the development of allergic contact dermatitis (ACD), we used THP-1 cells as a surrogate for DC. Read More

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http://dx.doi.org/10.1007/s00204-019-02416-7DOI Listing
February 2019
6 Reads

Epidermal loss of phospholipase Cδ1 attenuates irritant contact dermatitis.

Biochem Biophys Res Commun 2019 Apr 18;511(2):330-335. Epub 2019 Feb 18.

Laboratory of Genome and Biosignals, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan; AMED-CREST, Japan Agency for Medical Research and Development, Tokyo, Japan. Electronic address:

Irritant contact dermatitis (ICD) is one of the most common inflammatory skin diseases caused by exposure to chemical irritants. Since chemical irritants primarily damage keratinocytes, these cells play a pivotal role in ICD. One of the phosphoinositide-metabolizing enzymes, phospholipase C (PLC) δ1, is abundantly expressed in keratinocytes. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0006291X193023
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http://dx.doi.org/10.1016/j.bbrc.2019.02.046DOI Listing
April 2019
4 Reads

Using Patch Testing to Improve Therapeutic Outcome in the Treatment of Hand Eczema in Vietnamese Patients.

Open Access Maced J Med Sci 2019 Jan 23;7(2):204-207. Epub 2019 Jan 23.

University of Rome G. Marconi, Rome, Italy.

Background: Hand eczema is a common chronic and relapsing skin disease with various clinical features. Hand eczema aetiology can be allergic contact dermatitis (ACD), irritant contact dermatitis (ICD), atopic dermatitis (AD) and unknown or combination causes. If the causative agents are not detected treatment of hand eczema will be a failure. Read More

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http://dx.doi.org/10.3889/oamjms.2019.051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364736PMC
January 2019
2 Reads

The Curious Cases of Burn by Fig Tree Leaves.

Indian J Dermatol 2019 Jan-Feb;64(1):71-73

Cardiac Anesthesia Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Phytophotodermatitis is a condition which is caused by contact with some plants containing furocoumarins. Furocoumarins in sap of fig tree are the main cause of its irritability when come in contact with the skin. The main symptoms are burning sensation and pain, itchy erythema, and edema, which usually begin 24 h after exposure. Read More

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http://dx.doi.org/10.4103/ijd.IJD_442_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340245PMC
February 2019
5 Reads

Bullous irritant contact dermatitis caused by an alcoholic extract from Juglans regia leaves.

Contact Dermatitis 2019 Feb 11. Epub 2019 Feb 11.

Section of Dermatology, Department of Medical Sciences, University of Ferrara, Ferrara, Italy.

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http://dx.doi.org/10.1111/cod.13240DOI Listing
February 2019
3 Reads

Filaggrin gene mutations in hand eczema patients in the Indian subcontinent: A prospective case-control study.

Contact Dermatitis 2019 Jan 25. Epub 2019 Jan 25.

Department of Dermatology, Venereology, and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Background: There are no Indian studies on the association between filaggrin gene (FLG) mutations and any dermatosis, including hand eczema.

Objectives: To determine the prevalence of FLG mutations in Indian hand eczema patients, and examine associations between such mutations and any aetiological type of hand eczema.

Materials And Methods: A total of 163 patients and 86 controls were included. Read More

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http://dx.doi.org/10.1111/cod.13233DOI Listing
January 2019
5 Reads

Erosio interdigitalis blastomycetica: A review of interdigital candidiasis.

Dermatol Online J 2018 Aug 15;24(8). Epub 2018 Aug 15.

Veterans Affairs Medical Center Brooklyn, New York SUNY Downstate, Department of Dermatology, Brooklyn, New York.

Erosio interdigitalis blastomycetica (EIB) is a Candida infection affecting the third web space, between the third and fourth fingers. In 1915, Gougerot and Goncea first described saccharomycetic organisms isolated from the hands and feet. Johannes Fabry later named it in 1917, well before the genus Candida was introduced in 1923. Read More

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August 2018
2 Reads

Asteraceae species as potential environmental factors of allergy.

Environ Sci Pollut Res Int 2019 Mar 21;26(7):6290-6300. Epub 2019 Jan 21.

Department of Botany, Subdepartment of Plants Biology, University of Life Sciences in Lublin, Akademicka 15, 20-950, Lublin, Poland.

The statistics from Europe and the USA have proven a high risk for skin diseases associated with plant contact. Therefore, plant-induced dermatitis is of increasing attention in dermatology. The focus of this paper was to present the current knowledge on aspects of contact allergy related to Asteraceae (Compositae) species. Read More

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http://dx.doi.org/10.1007/s11356-019-04146-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428906PMC
March 2019
5 Reads

Eugenol as a Promising Molecule for the Treatment of Dermatitis: Antioxidant and Anti-inflammatory Activities and Its Nanoformulation.

Oxid Med Cell Longev 2018 11;2018:8194849. Epub 2018 Dec 11.

Pharmaceutical and Cosmetics Studies Center, Faculty of Pharmacy, Dentistry and Nursing, Federal University of Ceará, Fortaleza, Ceará, Brazil.

Contact dermatitis produces an inflammatory reaction primarily via stimulation of keratinocytes and cells of the immune system, which promote the release of cytokines, reactive oxygen species (ROS), and other chemical mediators. Eugenol (EUG, phenylpropanoid of essential oils) has attracted attention due to its anti-inflammatory properties, as well as antioxidant effect. On the other hand, it is volatile and insoluble and is a skin irritant. Read More

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https://www.hindawi.com/journals/omcl/2018/8194849/
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http://dx.doi.org/10.1155/2018/8194849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311755PMC
February 2019
10 Reads

Patients with Negative Patch Tests: Retrospective Analysis of North American Contact Dermatitis Group (NACDG) Data 2001-2016.

J Am Acad Dermatol 2019 Jan 11. Epub 2019 Jan 11.

Division of Dermatology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.

Background: Little is known regarding characteristics of patients with negative patch tests (NPTs).

Objective: To characterize patients with NPTs.

Methods: Retrospective cross-sectional analysis of 34,822 patch tested patients. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01909622193006
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http://dx.doi.org/10.1016/j.jaad.2018.12.062DOI Listing
January 2019
15 Reads

Anatomical site differences of sodium lauryl sulfate-induced irritation: randomized controlled trial.

Br J Dermatol 2019 Jan 13. Epub 2019 Jan 13.

Department of Pharmacy, University of Split School of Medicine, Šoltanska 2, 21000, Split, Croatia.

Background: Sodium lauryl sulfate (SLS)-induced contact dermatitis is a commonly used model for testing the effects of different topical formulations. According to the guidelines, the volar forearms are the preferred testing site; however, other anatomical locations have been used in previous research, particularly the upper back as the clinically used site for testing different antigens.

Objectives: To investigate the existence of anatomical variations of the skin response to irritation and its effects on the response to treatment. Read More

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http://dx.doi.org/10.1111/bjd.17633DOI Listing
January 2019
5 Reads

Cariniana domestica fruit peels present topical anti-inflammatory efficacy in a mouse model of skin inflammation.

Naunyn Schmiedebergs Arch Pharmacol 2019 May 7;392(5):513-528. Epub 2019 Jan 7.

Laboratory Neurotoxicity and Psychopharmacology, Graduate Program in Biological Sciences: Toxicological Biochemistry, Center of Natural and Exact Sciences, Federal University of Santa Maria, Av. Roraima 1000, Camobi, Santa Maria, RS, 97105-900, Brazil.

To investigate the topical anti-inflammatory activity of the crude extract of Cariniana domestica fruit peels (CdE), its dichloromethane, n-butanol, and ethyl acetate (EtAc) fractions, and steroids (β-sitosterol, lupeol, and stigmasterol) isolated from the EtAc fraction in models of irritant contact dermatitis (ICD) croton oil-induced in mice. We induced skin inflammation by single (acute; 1 mg/ear) and multiple (chronic; 0.4 mg/ear) croton oil application. Read More

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http://dx.doi.org/10.1007/s00210-018-1594-1DOI Listing
May 2019
3 Reads

Thermography: High sensitivity and specificity diagnosing contact dermatitis in patch testing.

Allergol Int 2019 Apr 29;68(2):254-258. Epub 2018 Dec 29.

Department of Dermatology, University Hospital Zurich, Zurich, Switzerland; Faculty of Medicine, University of Zurich, Zurich, Switzerland; Competence Center Personalized Medicine, University of Zurich and ETH Zurich, Zurich, Switzerland. Electronic address:

Background: Patch testing of contact allergens to diagnose allergic contact dermatitis (ACD) is a traditional, useful tool. The most important decision is the distinction between allergic and irritant reactions, as this has direct implications on diagnosis and management. Our objective was to evaluate a new method of non-contact infrared reading of patch tests. Read More

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http://dx.doi.org/10.1016/j.alit.2018.12.001DOI Listing
April 2019
5 Reads

Mechanics hands in patients with antisynthetase syndrome: 25 cases.

Ann Dermatol Venereol 2019 Jan 28;146(1):19-25. Epub 2018 Dec 28.

Dermatology clinic, université de Strasbourg, hôpitaux universitaires de Strasbourg, 1, place de l'Hôpital, 67000 Strasbourg, France.

Background: Antisynthetase antibodies (ASA) are directed against aminoacyl-tRNA-synthetases, ubiquitous enzymes of which eight types have hitherto been described. They are seen primarily in antisynthetase syndrome (ASS), in which diffuse interstitial lung disease is associated with inflammatory myopathy, joint involvement and cutaneous signs, in particular mechanic's hands. The aim of this study was to determine the prevalence and semiological characteristics of cutaneous involvement in patients presenting ASA. Read More

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http://dx.doi.org/10.1016/j.annder.2018.11.010DOI Listing
January 2019
3 Reads

Phytodermatitis in East and southeast of Turkey: A prospective study.

Authors:
Isa An Murat Ozturk

Cutan Ocul Toxicol 2019 Jun 17;38(2):176-181. Epub 2019 Feb 17.

b Department of Dermatology , Health Sciences Universty Van Training and Research Hospital , Van , Turkey.

Objective: Some plants may cause cutaneous side effects called phytodermatitis due to skin contact. Plants that cause phytodermatitis vary according to countries and regions. The aim of this study was to examine the phytodermatitis cases seen in Turkey's east and southeast and compare them with phytodermatitis cases seen previously in the literature in these provinces and to revise the literature. Read More

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http://dx.doi.org/10.1080/15569527.2018.1561711DOI Listing
June 2019
5 Reads

"Slime" dermatitis, a fad-associated chronic hand dermatitis.

Pediatr Dermatol 2019 Jan 16;36(1):e39-e40. Epub 2018 Dec 16.

Division of Dermatology, Children's National Health Center, Washington, District of Columbia.

"Slime" is the colloquial name for a non-Newtonian viscoelastic putty-like substance that is currently a popular plaything among pre-teens and adolescents. Several ingredients in homemade slime recipes may cause irritant or allergic contact dermatitis. We report two children who developed slime-associated chronic hand dermatitis, more prominently on their dominant hand. Read More

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http://dx.doi.org/10.1111/pde.13729DOI Listing
January 2019
3 Reads

Occupational contact dermatitis caused by isopropanol-containing disinfectant based on a genetic defect.

Contact Dermatitis 2019 May 16;80(5):316-318. Epub 2019 Jan 16.

Department of Dermatology and Venerology, Medical University of Graz, Graz, Austria.

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http://dx.doi.org/10.1111/cod.13197DOI Listing
May 2019
10 Reads

Topical anti-inflammatory and anti-oxidative effects of porcine placenta extracts on 2,4-dinitrochlorobenzene-induced contact dermatitis.

BMC Complement Altern Med 2018 Dec 12;18(1):331. Epub 2018 Dec 12.

Department of Biomedical Science and Engineering, Konkuk Institute of Technology, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul, 05029, South Korea.

Background: The placenta is a reservoir enriched with growth factors, hormones, cytokines and minerals. While several beneficial effects of placenta extracts on wound healing, anti-aging and anti-inflammatory responses have been reported, relatively limited mechanistic exploration has been conducted to date. Here, we provide compelling evidence of anti-inflammatory and anti-oxidative activities of porcine placenta extracts (PPE) against contact dermatitis in vivo. Read More

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http://dx.doi.org/10.1186/s12906-018-2396-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291973PMC
December 2018
2 Reads

Interdisciplinary and multiprofessional outpatient secondary individual prevention of work-related skin diseases in the metalworking industry: 1-year follow-up of a patient cohort.

BMC Dermatol 2018 12 12;18(1):12. Epub 2018 Dec 12.

Department of Dermatology, Klinikum Dortmund gGmbH, Beurhausstr. 40, 44137, Dortmund, Germany.

Background: In Germany, work-related skin diseases are predominant within the spectrum of reported occupational diseases. Metal workers are among the high-risk professions. Offering effective prevention programs to affected patients is of utmost importance to avoid deterioration of the disease and job loss. Read More

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http://dx.doi.org/10.1186/s12895-018-0080-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292163PMC
December 2018
2 Reads

Variation and covariation in patch test reactivity to palladium and nickel salts.

Eur J Dermatol 2018 Oct;28(5):668-676

Lund University, Skåne University Hospital, Department of Occupational and Environmental Dermatology, S-214 28, Malmö, Sweden.

Concomitant reactions to palladium chloride (PdCl), sodium tetrachloropalladate (NaPdCl), and nickel hexahydrate sulphate (NiSO·6HO) are very common during patch testing and have mainly been explained by cross-sensitisation. Whether there is variation in reactivity to palladium or covariation to nickel and palladium is not known. The aim of this study was to investigate the variation in patch test reactivity to PdCl and NaPdCl over time and compare this to variation in patch test reactivity to NiSO·6HO. Read More

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http://dx.doi.org/10.1684/ejd.2018.3423DOI Listing
October 2018
3 Reads

Associations Between Immune Phenotype and Inflammation in Murine Models of Irritant Contact Dermatitis.

Toxicol Sci 2019 Mar;168(1):179-189

Pharmaceutical Sciences Department, University of Oklahoma Health Science Center, Oklahoma City, Oklahoma 73117.

Irritant contact dermatitis (ICD), the most common occupational cutaneous illness, is an acute inflammatory response caused by topical irritant exposure. Multiple factors are associated with the manifestation and severity of ICD and contribute to the lack of effective prophylactic and treatment strategies. To determine the pathomechanism of ICD caused by the irritants, benzalkonium chloride (BKC) and JP-8 jet fuel, 2 mouse strains, C57BL/6 and Balb/c, were assessed due to their differential immune predispositions. Read More

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http://dx.doi.org/10.1093/toxsci/kfy289DOI Listing
March 2019
9 Reads

Contact dermatitis and sensitization in professional musicians.

Contact Dermatitis 2019 May 14;80(5):273-278. Epub 2019 Jan 14.

Department of Dermatology and Allergology, Allergy-Centre-Charité, Charité - Universitätsmedizin Berlin, Berlin, Germany.

Background: Professional musicians have prolonged and intense physical contact with their instruments. This can lead to occupational skin diseases, particularly irritant and allergic contact dermatitis.

Objectives: To assess the skin diseases and sensitization patterns common among professional musicians. Read More

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http://dx.doi.org/10.1111/cod.13191DOI Listing
May 2019
4 Reads

Characteristics of persistent diaper dermatitis in children with food allergy.

Pediatr Dermatol 2018 Nov 28. Epub 2018 Nov 28.

Department of Pediatrics, Medical Faculty, Inonu University, Malatya, Turkey.

Background/objectives: Diaper dermatitis is often caused by irritant contact occurring beneath the diaper of an infant, and it is aggravated by factors such as dampness, friction, urea, and feces. Food-allergic patients are known to exhibit various skin lesions ranging from urticaria to eczema. This study aims to determine the relationship between persistent diaper dermatitis and food allergy. Read More

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http://dx.doi.org/10.1111/pde.13733DOI Listing
November 2018
6 Reads

Evaluation of the profile of inflammatory cytokines, through immunohistochemistry, in the skin of patients with allergic contact dermatitis to nickel in the acute and chronic phases.

An Bras Dermatol 2018 Nov/Dec;93(6):829-835

Department of Dermatology, Faculdade de Medicina, Universidade de São Paulo, São Paulo (SP), Brazil.

Background: Allergic contact dermatitis to ion nickel (Ni+2) is an inflammatory dermatosis, common in industrialized countries. It involves the activation of nickel-specific T-cells, followed by proliferation and induction of a mixed profile of both proinflammatory and regulatory cytokines, suggesting that several T-cell subtypes (helper - Th and cytotoxic - Tc) are involved. A broader understanding of the cytokine profile may lead to new therapeutic approaches. Read More

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http://dx.doi.org/10.1590/abd1806-4841.20187126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256231PMC
February 2019
4 Reads

Contact Dermatitis: Emerging Trends.

Dermatol Clin 2019 Jan 1;37(1):21-28. Epub 2018 Nov 1.

The Ronald O. Perelman Department of Dermatology, New York University School of Medicine, 240 East 38th Street, Floor 11, New York, NY 10016, USA.

The field of contact dermatitis is constantly evolving. Trends in irritant and allergic contact dermatitis are shaped by the introduction of new chemicals, revival of older allergens, industrial practices, and consumer behaviors. This article discusses the most noteworthy trends within the field, organized by allergen category, with particular attention to newer and/or controversial allergens. Read More

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http://dx.doi.org/10.1016/j.det.2018.07.005DOI Listing
January 2019
5 Reads

Tabernaemontana catharinensis leaves exhibit topical anti-inflammatory activity without causing toxicity.

J Ethnopharmacol 2019 Mar 13;231:205-216. Epub 2018 Nov 13.

Laboratory Neurotoxicity and Psychopharmacology, Graduate Program in Biological Sciences: Toxicological Biochemistry, Center of Natural and Exact Sciences, Federal University of Santa Maria, Santa Maria, RS, Brazil. Electronic address:

Background: Tabernaemontana catharinensis, popularly known as snake skin, has been empirically used as an anti-inflammatory to treat cutaneous skin disorders. However, no study proves its effectiveness as a topical anti-inflammatory.

Study Design: We investigated the topical anti-inflammatory effect of T. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03788741183329
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http://dx.doi.org/10.1016/j.jep.2018.11.021DOI Listing
March 2019
20 Reads

Differential Diagnosis of Cheilitis - How to Classify Cheilitis?

Acta Clin Croat 2018 Jun;57(2):342-351

Department of Dermatovenereology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia.

Although cheilitis as a term describing lip inflammation has been identified and recognized for a long time, until now there have been no clear recommendations for its work-up and classification. The disease may appear as an isolated condition or as part of certain systemic diseases/conditions (such as anemia due to vitamin B12 or iron deficiency) or local infections (e.g. Read More

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https://hrcak.srce.hr/index.php?show=clanak&id_clanak_je
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http://dx.doi.org/10.20471/acc.2018.57.02.16DOI Listing
June 2018
21 Reads

A review of non-glove personal protective equipment-related occupational dermatoses reported to EPIDERM between 1993 and 2013.

Contact Dermatitis 2019 Apr 10;80(4):217-221. Epub 2019 Jan 10.

Centre for Occupational and Environmental Health, University of Manchester, Oxford Road, Manchester, UK.

Background: Personal protective equipment (PPE) is defined as equipment that protects the wearer's body against health/safety risks at work. Gloves cause many dermatoses. Non-glove PPE constitutes a wide array of garments. Read More

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http://doi.wiley.com/10.1111/cod.13177
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http://dx.doi.org/10.1111/cod.13177DOI Listing
April 2019
6 Reads

Contact dermatitis and atopic dermatitis- Two tales, an interwoven story.

G Ital Dermatol Venereol 2018 Nov 9. Epub 2018 Nov 9.

Department of Dermatology, Loma Linda University, Loma Linda, CA, USA -

Atopic dermatitis is a multifactorial disease that can concomitantly occur with irritant and allergic contact dermatitis. The colloquial use of atopic dermatitis and eczema interchangeably has created confusion among patients and providers alike. Atopic skin is a complex entity that involves a defective barrier and biome, an aberrant immune response, and abnormal neural activation, while eczema is a generalized term denoting a particular appearance common to multiple diagnoses including atopic dermatitis and contact dermatitis. Read More

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http://dx.doi.org/10.23736/S0392-0488.18.06236-3DOI Listing
November 2018
4 Reads

Evaluating the effect of electronic monitoring and feedback on hand cream use in healthcare workers: Healthy Hands Project.

Contact Dermatitis 2019 Jan 13;80(1):26-34. Epub 2018 Nov 13.

Coronel Institute of Occupational Health, Amsterdam Public Health Research Institute, Amsterdam UMC, Amsterdam, The Netherlands.

Background: Healthcare workers (HCWs) are at high risk of developing hand dermatitis (HD). Current guidelines on HD prevention recommend the use of emollients; however, in practice, adherence is poor.

Objective: To assess whether the provision of creams, electronic monitoring and feedback on cream consumption can improve skin care in HCWs. Read More

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http://doi.wiley.com/10.1111/cod.13148
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http://dx.doi.org/10.1111/cod.13148DOI Listing
January 2019
7 Reads

Comparison of Nickel Sulfate 2.5% and Nickel Sulfate 5% for Detecting Nickel Contact Allergy.

Dermatitis 2018 Nov/Dec;29(6):321-323

From the Department of Dermatology, Brigham and Women's Hospital, Chestnut Hill, MA.

Background: Nickel is among the most common contact allergens found on patch testing worldwide and, because of its ubiquitous nature in our environment, often has important implications for allergen avoidance strategies. In both North America and Europe, nickel positivity is found in approximately 20% of patients who undergo patch testing. Whereas in North America, nickel sulfate is typically tested at a concentration of 2. Read More

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http://dx.doi.org/10.1097/DER.0000000000000419DOI Listing
March 2019
19 Reads

Trends in Patch Testing With the Mayo Clinic Standard Series, 2011-2015.

Dermatitis 2018 Nov/Dec;29(6):310-315

Department of Dermatology and.

Background: Patch testing to a standard (baseline) series of allergens is the screening tool used to identify culprit allergens in patients with contact dermatitis. The allergens and concentrations used in a standard series are constantly evolving to be most relevant to the patients being patch tested.

Objective: The aim of this study was to analyze the 2011-2015 patch test results of the Mayo Clinic standard series. Read More

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http://dx.doi.org/10.1097/DER.0000000000000411DOI Listing
March 2019
18 Reads

Impact of water exposure on skin barrier permeability and ultrastructure.

Contact Dermatitis 2019 Apr 14;80(4):228-233. Epub 2018 Dec 14.

Biological Science Research, Kao Corporation, Tochigi, Japan.

Background: Skin occlusion caused by the use of diapers or sanitary napkins often results in irritant contact dermatitis. Furthermore, prolonged occlusion and exposure to body fluids are known to increase skin hydration and permeability, thus leading to irritant contact dermatitis.

Objective: To investigate the effects of water exposure on the skin and its barrier functions, in order to obtain more insights into the mechanisms of irritant contact dermatitis. Read More

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http://doi.wiley.com/10.1111/cod.13174
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http://dx.doi.org/10.1111/cod.13174DOI Listing
April 2019
16 Reads

Tabernaemontana catharinensis leaves effectively reduce the irritant contact dermatitis by glucocorticoid receptor-dependent pathway in mice.

Biomed Pharmacother 2019 Jan 4;109:646-657. Epub 2018 Nov 4.

Laboratory Neurotoxicity and Psychopharmacology, Graduate Program in Biological Sciences: Toxicological Biochemistry, Center of Natural and Exact Sciences, Federal University of Santa Maria, Santa Maria, RS, Brazil. Electronic address:

Ethnopharmacological Relevance: Tabernaemontana catharinensis, popularly known as snakeskin, is used in traditional medicine to treat skin inflammatory disorders. To confirm the topical anti-inflammatory effect of T. catharinensis leaves, we evaluated the therapeutic effect of crude extract (TcE) and its different fractions on irritant contact dermatitis model in mice and verified its anti-inflammatory action mechanism. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07533322183629
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http://dx.doi.org/10.1016/j.biopha.2018.10.132DOI Listing
January 2019
26 Reads

Anti-inflammatory Effects of Variola Virus TNF Decoy Receptor in an Experimental Model of Contact Dermatitis.

Curr Pharm Biotechnol 2018 ;19(11):910-916

Federal State Budgetary Institution "Research Institute of Basic and Clinical Immunology", Novosibirsk, Russian Federation.

Background: Large DNA poxviruses encode a diverse family of secreted proteins that modulate host inflammatory and antiviral responses, in particular by inhibiting one of the key players of the mammalian immune system, the tumor necrosis factor (TNF).

Methods: We investigated the effects of a recombinant variola (smallpox) virus TNF-decoy receptor (VARV-CrmB) in a murine model of contact dermatitis. Our results demonstrate that the VARV-CrmB protein significantly reduces the 2,4-dinitrochlorbenzene (DNCB)-induced migration of skin leukocytes during the sensitization phase and suppresses ear oedema during the elicitation phase of the contact reaction. Read More

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http://dx.doi.org/10.2174/1389201019666181029111011DOI Listing
March 2019
40 Reads
2.511 Impact Factor

Gerontodermatology: the fragility of the epidermis in older adults.

J Eur Acad Dermatol Venereol 2018 Nov;32 Suppl 4:1-20

Pharmacology Division, Pierre Fabre Dermo-Cosmétique, Toulouse, France.

The proportion of adults over 60 years of age is rapidly increasing and is estimated to reach approximately one-sixth of the global population by 2030. An ageing population is a real challenge for healthcare resources, including dermatologists and geriatricians, as age-related changes in skin integrity and barrier function make older adults more susceptible to developing skin pathologies such as pruritus, dermatitis and infections. Fragile skin arises from several interlinked causes, including age-related changes in skin barrier integrity, previous and current lifestyle choices, skin pathologies and medical interventions. Read More

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http://doi.wiley.com/10.1111/jdv.15253
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http://dx.doi.org/10.1111/jdv.15253DOI Listing
November 2018
19 Reads

Atypical Skin Inflammation in a 2.5-Year-Old Girl With Atopic Dermatitis.

J Investig Allergol Clin Immunol 2018 Oct;28(5):336-338

Department of Pediatrics, Allergology and Gastroenterology Collegium Medicum Bydgoszcz, Nicolaus Copernicus University of Torun, Poland.

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http://dx.doi.org/10.18176/jiaci.0276DOI Listing
October 2018
5 Reads

Contact Dermatitis Caused by Dermabond Advanced Use.

Plast Reconstr Surg Glob Open 2018 Sep 14;6(9):e1841. Epub 2018 Sep 14.

Department of Plastic Surgery, Jichi Medical University, Tochigi, Japan.

Background: Dermabond Advanced (DBA) has been widely used globally; however, severe contact dermatitis (CD) can be a serious adverse effect of DBA use. In this study, we investigated the characterization and incidence rate of CD after using DBA and the safe use of DBA.

Methods: One hundred consecutive patients who underwent skin closure with DBA were investigated. Read More

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http://Insights.ovid.com/crossref?an=01720096-201809000-0001
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http://dx.doi.org/10.1097/GOX.0000000000001841DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191225PMC
September 2018
16 Reads