5,065 results match your criteria Contact Dermatitis Irritant

Botanical Briefs: Phytophotodermatitis Is an Occupational and Recreational Dermatosis in the Limelight.

Cutis 2021 Apr;107(4):187-189

Rutgers New Jersey Medical School, Newark. Dr. Schwartz from the Departments of Dermatology, Pathology, Pediatrics, and Medicine. Mr. Janusz also is from Saint Joseph University, Philadelphia, Pennsylvania.

Phytophotodermatitis (PPD) is a toxic reaction resulting from contact with a photosensitizing botanical chemical followed by exposure to solar or artificial UV light. It may present with bizarre patterns and linear streaks due to a phototoxic agent splashing onto various cutaneous sites; thus, it affects the skin at points of contact and exposure to UV light. Individuals typically experience symptoms within 24 hours of exposure. Read More

View Article and Full-Text PDF

Wood ash and water: Cause of superficial alkaline burns in a toddler.

Pediatr Dermatol 2021 Jun 6. Epub 2021 Jun 6.

Missouri Poison Center, St. Louis, Missouri, USA.

Though seemingly innocuous, the combination of wood ash and water can result in an alkaline solution with a pH up to 12, making it a burn risk. A 2-year-old boy developed a significant irritant reaction to his arms and legs while playing outdoors in wood ashes with a water gun. This case is novel because an unintentional, trivial exposure resulted in ulcerative irritant dermatitis. Read More

View Article and Full-Text PDF

Diagnosis and Management of Dermatitis, Including Atopic, Contact, and Hand Eczemas.

Med Clin North Am 2021 Jul;105(4):611-626

Geisel School of Medicine at Dartmouth, Hanover, NH, USA; Department of Dermatology, Dartmouth-Hitchcock Medical Center, 18 Old Etna Road, Lebanon, NH 03766, USA.

This is a comprehensive and current guide for the diagnosis, differential diagnosis, treatment, and management of eczematous dermatitis, with a focus on atopic dermatitis, irritant and allergic contact dermatitis, hand dermatitis including recurrent vesicular and hyperkeratotic types, asteatotic dermatitis, and nummular or discoid dermatitis. Diagnostic options highlighted are clinical history, physical examination, and patch testing. Therapeutic options highlighted are moisturizers, topical corticosteroids, topical calcineurin inhibitors, crisaborole, phototherapy, and systemic medications including biologics. Read More

View Article and Full-Text PDF

Contact dermatitis.

Nat Rev Dis Primers 2021 May 27;7(1):38. Epub 2021 May 27.

Department of Dermatology, Brigham and Women's Hospital, Boston, MA, USA.

Contact dermatitis (CD) is among the most common inflammatory dermatological conditions and includes allergic CD, photoallergic CD, irritant CD, photoirritant CD (also called phototoxic CD) and protein CD. Occupational CD can be of any type and is the most prevalent occupational skin disease. Each CD type is characterized by different immunological mechanisms and/or requisite exposures. Read More

View Article and Full-Text PDF

Contact Dermatitis in Children.

Pediatr Ann 2021 May 1;50(5):e198-e205. Epub 2021 May 1.

Contact dermatitis (CD) is commonly encountered in the pediatric population. Allergic and irritant are the two forms of CD and both cause significant clinical problems in children, but they are often underrecognized. The skin lesions in CD may be polymorphic and closely mimic other common pediatric skin diseases. Read More

View Article and Full-Text PDF

Impact of mono-culture vs. Co-culture of keratinocytes and monocytes on cytokine responses induced by important skin sensitizers.

J Immunotoxicol 2021 Dec;18(1):74-84

Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden.

Sensitization to a contact allergen brings with it a lifelong risk to develop allergic contact dermatitis. Inflammation is an important part of the skin sensitizing mechanism, and understanding how different haptens stimulate the immune system, as well as the role played by different cell types present in skin, may be helpful for developing optimized models for risk assessment of new chemicals or mixtures. The aim of this study was to compare the cytokine profile following exposure of cells representing keratinocytes (HaCaT), monocytes (THP-1) and a co-culture of these cells to three clinically important skin sensitizers: cobalt (II) chloride (CoCl), methylisothiazolinone (MI) and p-phenylenediamine (PPD). Read More

View Article and Full-Text PDF
December 2021

Contact allergen sensitivity in children with contact dermatitis.

Turk Arch Pediatr 2021 Jan 1;56(1):51-56. Epub 2021 Jan 1.

Pediatric Allergy and Immunology Clinic, University of Health Sciences, Okmeydanı Training and Research Hospital, İstanbul, Turkey.

Objective: Irritant contact dermatitis and Allergic contact dermatitis are two distinct forms of contact dermatitis. Allergic contact dermatitis is a Type 4 (delayed-type) hypersensitivity reaction that occurs during subsequent contact with an allergen to a previously sensitized person. The number of allergens that cause allergic contact dermatitis is increasing day by day. Read More

View Article and Full-Text PDF
January 2021

Allergic contact versus irritant contact dermatitis in patients with hard-to-heal leg ulcer: clinical and diagnostic approach.

J Wound Care 2021 May;30(5):394-398

Dermatology Department, University of Chieti and Pescara, Italy.

Background: Dermatitis of surrounding skin may complicate hard-to-heal leg ulcers, delaying wound healing. The coexistence of hard-to-heal leg ulcers and irritant or allergic contact dermatitis may create difficulties for both diagnostic and therapeutic management.

Objective: The aim of our study was to evaluate the incidence of dermatitis occurring in the surrounding skin in a population affected by hard-to-heal leg ulcers during treatment, and to differentiate between allergic contact dermatitis (ACD) and irritant contact dermatitis (ICD) with the use of a patch test. Read More

View Article and Full-Text PDF

Are Topical Corticosteroids Effective for Chronic Irritant Contact Dermatitis?

Dermatitis 2021 May 10. Epub 2021 May 10.

Department of Medicine, Tulane University School of Medicine, New Orleans, LA Department of Dermatology, University of California San Francisco.

View Article and Full-Text PDF

Masks use and facial dermatitis during COVID-19 outbreak: is there a difference between CE and non-CE approved masks? Multi-center, real-life data from a large Italian cohort.

Ital J Dermatol Venerol 2021 Apr;156(2):220-225

Department of Clinical Dermatology, IRCCS Galeazzi Orthopedic Institute, Milan, Italy.

Background: During the recent COVID-19 outbreak, masks became mandatory and shortages frequent, therefore the prevalence of non-CE (European Conformity Mark) approved masks increased in the general population. We aimed to quantify the prevalence of mask-related cutaneous side effects and the differences between CE and non-CE approved masks.

Methods: In this multicenter prospective observational study conducted from March 20, 2020 to May 12, 2020(during and after quarantine), patients attending emergency departments for a dermatological consult were clinically assessed and their masks were inspected to detect CE marks and UNI (Italian National Unification Entity) norms. Read More

View Article and Full-Text PDF

Contact Dermatitis of the Hands: Is It Irritant or Allergic?

Cutis 2021 Mar;107(3):129-132

Mr. Patel and Dr. Reeder are from the University of Wisconsin School of Medicine and Public Health, Madison. Dr. Reeder is from the Department of Dermatology. Dr. Atwater is from the Department of Dermatology, Duke University School of Medicine, Durham, North Carolina.

Hand contact dermatitis is common, and irritant contact dermatitis (ICD) is more likely than allergic contact dermatitis (ACD) in both occupational and nonoccupational settings. Irritant contact dermatitis can have acute and chronic presentations, and hand hygiene products can contribute. The most common relevant hand contact allergens in North American patch test populations are methylisothiazolinone (MI), nickel, formaldehyde, quaternium-15, and fragrance mix I. Read More

View Article and Full-Text PDF

Topical Applications of a Novel Emollient Inhibit Inflammation in Murine Models of Acute Contact Dermatitis.

Biomed Res Int 2021 13;2021:5594646. Epub 2021 Apr 13.

Dermatology Hospital of Southern Medical University, Guangdong 510091, China.

The benefits of emollients for eczematous dermatitis and psoriasis have been thought to be due to the improvements in epidermal function, including epidermal permeability barrier, stratum corneum hydration, and stratum corneum pH. We determined here whether emollient can direct inhibit cutaneous inflammation. Ear inflammation was induced by topical application of either 12-O-tetradecanoylphorbol-13-acetate (TPA) or 1-fluoro-2,4-dinitrofluorobenzene (DNFB). Read More

View Article and Full-Text PDF

Contact Dermatitis and Medical Adhesives: A Review.

Cureus 2021 Mar 24;13(3):e14090. Epub 2021 Mar 24.

Plastic and Reconstructive Surgery, Baylor College of Medicine, Houston, USA.

In more recent years, the use of medical adhesives in lieu of sutures or staples has become increasingly common for the closure of post-surgical and traumatic incisions in areas of the skin where tension is low. While medical adhesives possess many advantages and little risk of adverse side effects, there are increasing numbers of accounts in the medical literature of allergic contact dermatitis (ACD) caused by specific components contained within the medical adhesives. The goal of this paper is to provide physicians with a differential diagnosis when faced with complications after the use of medical adhesives for wound closure. Read More

View Article and Full-Text PDF

Art of prevention: Allergic sensitization through damaged skin: Atopic, occupational, and stasis dermatitis.

Int J Womens Dermatol 2020 Dec 19;6(5):381-383. Epub 2020 Aug 19.

University Hospitals Cleveland Medical Center/Case Western Reserve University School of Medicine, United States.

The prevention of allergic contact dermatitis hinges on maintaining the integrity of the skin barrier and responding appropriately when it is disturbed. Although intact skin is subject to sensitization via highly irritating allergens, such as poison ivy, acutely inflamed and chronically inflamed skin is subject to sensitization to allergens without inherent irritant potential. In the chronically inflamed state of atopic dermatitis, sensitization to proteins, such as food, also carries a risk for systemic contact dermatitis via ingestion of the allergen. Read More

View Article and Full-Text PDF
December 2020

Art of prevention: Practical interventions in lip-licking dermatitis.

Int J Womens Dermatol 2020 Dec 5;6(5):377-380. Epub 2020 Jun 5.

Department of Dermatology, University of Missouri - Columbia, Columbia, MO, United States.

Dry, cracked lips are a common occurrence in both cold winter months and arid climates, leading many patients to experience discomfort year-round. Lip-licking is a compensatory measure that perpetuates the condition and often leads to lip-licking dermatitis. In patients in whom this compensatory measure becomes a chronic habit, other sequelae such as irritant contact dermatitis, cheilitis simplex, angular cheilitis, factitial cheilitis, secondary infections, and exfoliative cheilitis can arise. Read More

View Article and Full-Text PDF
December 2020

A case of neutrophilic superficial eccrine ductitis.

JAAD Case Rep 2021 May 17;11:69-71. Epub 2021 Feb 17.

Department of Dermatology, Icahn School of Medicine at Mount Sinai Hospital, New York, New York.

View Article and Full-Text PDF

What's Eating You? Black Butterfly (Hylesia nigricans).

Cutis 2021 Feb;107(2):68-70

Dr. González is from the Dermatology Service, Kennedy Hospital, Bogotá, Colombia. Dr. Sandoval is from the Dermatology Program, El Bosque University, Bogotá. Drs. Motta and Rolón are from Simón Bolívar Hospital, Bogotá. Dr. Motta is from the Dermatology Service, and Dr. Rolón is from the Dermatopathology Service.

Lepidopterism refers to the adverse medical effects of contact with insects of the order Lepidoptera, which includes both moths and butterflies. These effects typically result from contact with an insect during the caterpillar (larval) stage. Lepidopterism involves multiple pathologic mechanisms, including direct toxicity of venom and mechanical irritant effects. Read More

View Article and Full-Text PDF
February 2021

[Exceptional occupational allergies due to food of animal origin].

H Dickel

Hautarzt 2021 Jun 20;72(6):493-501. Epub 2021 Apr 20.

Klinik für Dermatologie, Venerologie und Allergologie, St. Josef-Hospital, Universitätsklinikum der Ruhr-Universität Bochum (UK RUB), Gudrunstr. 56, 44791, Bochum, Deutschland.

Background: The food industry is a high-risk area for work-related allergic immediate skin reactions (contact urticaria, contact urticaria syndrome, protein contact dermatitis) with or without respiratory symptoms (allergic rhinitis, allergic asthma) due to proteins of animal origin.

Objectives: The present work gives an overview of allergenic seafood and meat proteins and their clinical and occupational relevance in different work settings.

Methods: A review of current knowledge and a supplementary selective literature search were performed. Read More

View Article and Full-Text PDF

ARTICLE: Compromised Skin Barrier and Sensitive Skin in Diverse Populations.

J Drugs Dermatol 2021 Apr;20(4):s17-s22

The most important function of the stratum corneum (SC), the uppermost layer of the human epidermis, is the formation of the epidermal permeability barrier. Lipids, particularly ceramides, cholesterol, and free fatty acids, together form lamellar membranes in the extracellular spaces of the SC that limit the loss of water and electrolytes. In addition to preventing water and electrolyte loss, the SC as a permeability barrier prevents the entry of harmful irritants, allergens, and microorganisms into the skin. Read More

View Article and Full-Text PDF

Inter-rater variability in patch test readings and final interpretation using store-forward teledermatology.

Contact Dermatitis 2021 Apr 9. Epub 2021 Apr 9.

Department of Dermatology, Minneapolis Veterans Affairs Medical Center, Minneapolis, Minnesota, USA.

Background: Data regarding teledermatology for patch testing are limited.

Objectives: Compare patch test readings and final interpretation by two in-person dermatologists (IPDs) with eight teledermatologists (TDs).

Methods: Patch tested patients had photographs taken of 70 screening series of allergens at 48 hours and second readings. Read More

View Article and Full-Text PDF

Paederus Dermatitis Outbreak in Addis Ababa, Ethiopia: A Case-Control Study.

J Environ Public Health 2021 15;2021:8892785. Epub 2021 Mar 15.

Center of Public Health Emergency Management, Ethiopian Public Health Institutes, Swaziland Street, P.O. Box 1242, Addis Ababa, Ethiopia.

Background: Paederus dermatitis is an irritant contact dermatitis caused by crushing insects of the genus , which releases a vesicant toxin called pederin. On July 28, 2018, the district health office received a report of cases with erythema, itching, and burning after contact with the insect. In response, we investigated the outbreak intending to describe, confirm, and identify the risk factors associated with the country's first reported outbreak. Read More

View Article and Full-Text PDF

Effect of on DNCB-Induced Allergic Contact Dermatitis-Like Skin Lesion in Balb/c Mice.

Nutrients 2021 Mar 4;13(3). Epub 2021 Mar 4.

Department of Anatomy, College of Korean Medicine, Kyung Hee University, 26, Kyunghee dae-ro, Dongdaemun-gu, Seoul 02447, Korea.

(CP), or Korean red pinecone, is a cluster of fruit. CP has also been verified in several studies to have anti-oxidation, anti-fungal, anti-bacterial, and anti-melanogenic effects. However, anti-inflammatory effects have not yet been confirmed in the inflammatory responses of pinecones to allergic contact dermatitis. Read More

View Article and Full-Text PDF

Irritant Contact Dermatitis Due to Euphorbia milii: No Rose Without a Thorn.

Dermatitis 2021 Mar 12. Epub 2021 Mar 12.

From the Department of Dermatology, Chang Gung Memorial Hospital College of Medicine, Chang Gung University Department of Cosmetic Science, Chang Gung University of Science and Technology Center of Tissue Engineering, Chang Gung Memorial Hospital, Taoyuan, Taiwan.

View Article and Full-Text PDF

Structured diagnostic assessment of hand eczema in cleaning workers.

J Dtsch Dermatol Ges 2021 05 25;19(5):672-676. Epub 2021 Mar 25.

Dermatology, Basel University Hospital and Basel University, Basel, Switzerland.

Hand dermatitis is a widespread problem among cleaners. In most cases, it is caused by a combination of wet work and contact with irritants, which can result in irritant (toxic) contact dermatitis. In some cases, the irritant contact eczema then evolves into allergic contact dermatitis, although not all cases of allergic contact dermatitis are preceded by irritant contact dermatitis. Read More

View Article and Full-Text PDF

Double blind randomized repetitive efficacy test of various occupational skin protection preparations against sodium lauryl sulphate.

J Dtsch Dermatol Ges 2021 04 25;19(4):545-552. Epub 2021 Mar 25.

Department of Dermatology, Jena University Medical Center.

Background: Skin protection products, formerly named as barrier creams, are being used as primary and secondary prevention measures against occupational dermatoses. Many of these cosmetic products are claimed by manufacturers to be efficacious against wet work-induced skin barrier impairment if applied prior to exposure. However, results of validated and standardized in vivo efficacy tests allowing the comparison of different products are lacking. Read More

View Article and Full-Text PDF

Clinical Pattern and Patch Test Profile of Hand Eczema in Hospital Employees in a Tertiary Care Hospital of North India.

Indian Dermatol Online J 2021 Jan-Feb;12(1):72-77. Epub 2021 Jan 16.

Department of Dermatology, Sexually Transmitted Diseases and Leprosy, Government Medical College, Srinagar, Jammu and Kashmir.

Introduction: Health care workers form an important occupational group with a high risk of hand eczema. All health care professionals are exposed to a variety of allergens and irritants which can cause hand dermatitis, resulting in significant morbidity.

Aims And Objectives: To assess the clinical profile of hand eczema in hospital employees, to perform patch test in relevant cases and to find out the most common sensitizers in them. Read More

View Article and Full-Text PDF
January 2021

Occupational contact dermatitis: Retrospective analysis of North American Contact Dermatitis Group Data, 2001 to 2016.

J Am Acad Dermatol 2021 Mar 19. Epub 2021 Mar 19.

Division of Occupational Medicine, Department of Medicine, St Michael's Hospital, Unity Health, University of Toronto, Toronto, Ontario, Canada.

Background: Patch testing is an important diagnostic tool for suspected allergic contact dermatitis (ACD) in occupational settings.

Objective: Provide an overview of occupational skin disease (OSD) and an analysis of occupational ACD in North American patients undergoing patch testing between 2001and 2016.

Methods: Patients with OSD were analyzed for frequency of allergic reactions to a screening series of allergens, occupational relevance, location of skin disease, and exposure sources. Read More

View Article and Full-Text PDF

European Surveillance System on Contact Allergies (ESSCA): Characteristics of patients patch tested and diagnosed with irritant contact dermatitis.

Contact Dermatitis 2021 Mar 17. Epub 2021 Mar 17.

Department of Dermatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

Background: Irritant contact dermatitis (ICD) is caused by the acute locally toxic effect of a strong irritant, or the cumulative exposure to various weaker physical and/or chemical irritants.

Objectives: To describe the characteristics of patients with ICD in the population patch tested in the European Surveillance System on Contact Allergies (ESSCA; www.essca-dc. Read More

View Article and Full-Text PDF

Contact allergy and allergic contact dermatitis from benzalkonium chloride in a tertiary dermatology center in Melbourne, Australia.

Contact Dermatitis 2021 Mar 3. Epub 2021 Mar 3.

Occupational Dermatology Research and Education Centre, Skin Health Institute, Carlton, Victoria, Australia.

Background: Benzalkonium chloride (BAK) is a quaternary ammonium compound that is used widely as an antiseptic and preservative. It is a strong irritant and considered a weak sensitizer.

Objective: To analyze the temporal trend of BAK sensitization and the demographics of sensitized patients. Read More

View Article and Full-Text PDF

Synthetic hair extensions causing irritant contact dermatitis in patients with a history of atopy: A report of 10 cases.

Contact Dermatitis 2021 Feb 28. Epub 2021 Feb 28.

Department of Medicine, Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa.

Background: We present a case series of 10, atopic, African women who developed irritant contact dermatitis (ICD) from synthetic hair extensions.

Methods: Ten consecutive African female patients who presented with a pruritic cutaneous eruption on the neck over a period of 2 years are described. Patients underwent skin patch testing using both standard and hair commercial patch test panels and samples of their own hair extensions. Read More

View Article and Full-Text PDF
February 2021