18,017 results match your criteria Contact Dermatitis Allergic


[Translated article] Contact Allergy in Patients With Rosacea.

Actas Dermosifiliogr 2022 Jun 10;113(6):T550-T554. Epub 2022 May 10.

Servicio de Dermatología, Hospital General Universitario de Valencia, Valencia, Spain.

Background And Objective: Rosacea is a chronic acneiform skin disorder in which impaired skin barrier function can lead to sensitization to allergens. We aimed to analyze contact allergies in our patients with rosacea.

Material And Methods: Retrospective cohort study of all patients who underwent patch testing in our skin allergy clinic between May 1991 and May 2019. Read More

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Patch testing with the European baseline series and 10 added allergens: single centre study of 748 patients.

Contact Dermatitis 2022 Jun 23. Epub 2022 Jun 23.

Faculty of Medicine, University of Maribor, Maribor, Slovenia.

Background: The European baseline series (EBS) of contact allergens is subject to change. An allergen is considered for inclusion when routine patch testing of patients with suspected contact dermatitis results in ≥ 0.5% prevalence rate. Read More

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Ocular allergy in children and adolescents.

Allergol Immunopathol (Madr) 2022 20;50(S Pt 1):30-36. Epub 2022 May 20.

Federal University of Parana, Curitiba, Brazil.

The association between symptoms of asthma, rhinoconjunctivitis (RC) and allergic conjunctivitis (AC) is frequent, and AC is considered a comorbidity of asthma and allergic rhinitis (AR). Ocular symptoms are often underestimated and undertreated.Differences according to gender were reported, because girls present symptoms more frequently. Read More

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A closer look at allergic contact dermatitis caused by topical ophthalmic medications.

Contact Dermatitis 2022 Jun 17. Epub 2022 Jun 17.

Dermatology Unit, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.

Background: Allergic contact dermatitis caused by topical ophthalmic medications (OftACD) is frequently difficult to confirm with patch testing and, therefore, it is considered uncommon.

Methods: We collected retrospective data from a cohort of 65 patients with suspected OftACD patch tested in our Dermatology Unit (2005-2021) according to ESCD guidelines, using a series of topical drugs and excipients (Chemotechnique Diagnostics™), including betaxolol and timolol 5% pet. kindly supplied by the pharmaceutical industry. Read More

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Occupational allergic contact dermatitis to sodium metabisulfite in shredded coconut.

Contact Dermatitis 2022 Jun 17. Epub 2022 Jun 17.

Department of Dermatology, Dartmouth-Hitchcock Medical Center, Lebanon, NH.

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Black-Spot Toxicodendron Dermatitis With Varied Presentation.

Wilderness Environ Med 2022 Jun 16. Epub 2022 Jun 16.

School of the Environment, Geography and Geosciences, University of Portsmouth, Portsmouth, UK.

This article describes the clinical presentation, differential diagnosis, and treatment of 2 unrelated cases with different presentations of black-spot Toxicodendron dermatitis. In the first case, a healthy 7-y-old male presented with a rash consisting of black dots with localized surrounding erythema on the left arm. The rash then progressed to a vesicular, pinpoint, raised rash spreading to the face, arms, and neck. Read More

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[ANALYSIS OF PATCH TEST RESULTS FOR INDIVIDUAL INGREDIENTS IN PATIENTS WITH ALLERGIC CONTACT DERMATITIS CAUSED BY 10% EFINACONAZOLE NAIL SOLUTION].

Arerugi 2022 ;71(4):313-320

Hanamizuki Clinic.

Background: Ten percent efinaconazole nail solution (EFCZ solution) is a new topical triazole antifungal drug, and we sometimes encounter patients with allergic contact dermatitis (ACD) caused by EFCZ solution in our outpatient clinic. However, no previous reports have summarized the patch test (PT) results obtained for individual ingredients in several patients with EFCZ solution-induced ACD.

Objectives: This study aimed to 1) confirm the causative agent of EFCZ solution-induced ACD based on PT of individual ingredients and 2) analyze the optimal concentration and vehicle for such PT on the basis of previous studies. Read More

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The immediate patch test reaction to fragrance in patients with allergic contact dermatitis to fragrance: A prospective study.

J Am Acad Dermatol 2022 Jun 8. Epub 2022 Jun 8.

Center of Excellence in Immunology and Immune-Mediated Diseases, Division of Immunology, Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. Electronic address:

Background: Fragrance is one of the common causes of immediate contact reaction. Knowing the population's prevalence enables prioritization of allergy screening.

Objective: The purpose of this study is to determine the prevalence of an immediate patch test reaction to fragrance in patients with fragrance allergic contact dermatitis. Read More

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Contact sensitization in pediatric patients with atopic dermatitis: a purpose for a new patch testing serie for the Portuguese population.

Eur Ann Allergy Clin Immunol 2022 Jun 9. Epub 2022 Jun 9.

Department of Dermatology, Coimbra University Hospital Center, Coimbra, Portugal.

Summary: Atopic dermatitis is a common illness in pediatric age. Children with atopic dermatitis are prone to develop cutaneous sensitization due to skin barrier dysfunction and immune dysregulation. Recent studies have shown a higher prevalence of certain allergens, which identification may be clinically relevant and have implications for atopic dermatitis management. Read More

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Role of IL-36 cytokines in psoriasis and other inflammatory skin conditions.

Cytokine 2022 Aug 6;156:155897. Epub 2022 Jun 6.

Immunology Discovery, Janssen Research and Development, San Diego, CA 92121, USA. Electronic address:

The IL-36 family of cytokines includes three pro-inflammatory agonists (IL-36α, IL-36β, and IL-36γ) and a receptor antagonist (IL-36Ra), which bind and signal through a heterodimeric receptor composed of IL-36R and the IL-1R accessory protein (IL-1RAcP). Individuals with inactivating mutations in the gene encoding IL-36Ra develop generalized pustular psoriasis, a severe form of psoriasis, a finding which clearly links dysregulated IL-36 pathway activation to inflammatory skin conditions. The purpose of this review is to highlight the cellular source of IL-36 cytokines, the effects of IL-36 signaling across cell types, and the association of IL-36 to a spectrum of inflammatory skin diseases including various forms of psoriasis as well as hidradenitis suppurativa, atopic dermatitis, and allergic contact dermatitis. Read More

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Contact allergens in moisturizers in preventative emollient therapy - A systematic review.

Clin Transl Allergy 2022 Jun 5;12(6):e12150. Epub 2022 Jun 5.

Department of Pediatric Pneumonology and Allergy Medical University of Warsaw Warsaw Poland.

Background: Results of preventative emollient therapy on atopic dermatitis and food allergy trials are inconsistent. In addition to the ingredients considered beneficial, the moisturizers may contain potentially harmful haptens. This study aimed to assess the prevalence of haptens in moisturizers used in studies to prevent atopic dermatitis or food allergy and assess their correlations to the trial results. Read More

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Formaldehyde Release From Eyelash Glues: Analysis Using the Chromotropic Acid Method.

Dermatitis 2022 Jun 8. Epub 2022 Jun 8.

Department of Dermatology, University of Minnesota, Minneapolis.

Background: Popularity of eyelash enhancements has increased dramatically. Eyelash enhancements are available as an over-the-counter consumer product with glue included and as a professional product where proprietary glues are typically used. Both types of eyelash extension glues may release formaldehyde despite not being declared as an ingredient. Read More

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Nonoccupational Allergic Contact Dermatitis to 4-Acryloylmorpholine in Smartwatch Screen Protectors Glue.

Dermatitis 2022 Jun 8. Epub 2022 Jun 8.

Department of Occupational and Environmental Dermatology, Lund University, Skåne University Hospital, Malmö, Sweden.

Background: We recently identified an outbreak of occupational allergic contact dermatitis (ACD) involving workers of a Spanish company selling smartphone protective cases from a glue product. A chemical analysis of one glue sample revealed the presence of 4-acryloylmorpholine among other allergens.The same glue is also used to attach tempered glass protective cases to Apple smartwatches. Read More

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Comparison of product safety data sheet ingredient lists with skin irritants and sensitizers present in a convenience sample of light-curing resins used in additive manufacturing.

Regul Toxicol Pharmacol 2022 May 31;133:105198. Epub 2022 May 31.

National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV, 26505, USA.

Material jetting and vat photopolymerization additive manufacturing (AM) processes use liquid resins to build objects. These resins can contain skin irritants and/or sensitizers but product safety data sheets (SDSs) might not declare all ingredients. We characterized elemental and organic skin irritants and sensitizers present in 39 commercial products; evaluated the influence of resin manufacturer, system, color, and AM process type on the presence of irritants and sensitizers; and compared product SDSs to results. Read More

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Patch Testing on Dupilumab: Reliable or Not?

Cutis 2022 03;109(3):158-159

Department of Dermatology, Northwestern University Feinberg School of Medicine and Medical Dermatology Associates of Chicago, both in Chicago, Illinois.

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Online Information-Seeking Behavior for Allergies and its Association with COVID-19 Vaccine-Hesitancy in India: An Info-Epidemiologic Study.

Indian J Dermatol 2022 Jan-Feb;67(1):92

Department of Physiology, Raiganj Government Medical College and Hospital, West Bengal, India.

Background: Vaccine-hesitancy is an important obstacle to attain herd-immunity against COVID-19. Undue fears about adverse effects like allergic reactions may be an important reason for vaccine-hesitancy.

Objectives: To assess the online information-seeking behavior of Indian internet users regarding 'allergies' and determine its association with COVID-19 vaccine-hesitancy. Read More

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A case of hair dye-induced allergic contact dermatitis in the context of nivolumab.

Contact Dermatitis 2022 Jun 2. Epub 2022 Jun 2.

Department of Dermatology, Liverpool Hospital Sydney, Liverpool, New South Wales, Australia.

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Quantitative analysis of fragrance allergens in various matrixes of cosmetics by liquid-liquid extraction and GC-MS.

J Food Drug Anal 2021 12 15;29(4):700-708. Epub 2021 Dec 15.

Food and Drug Administration, Ministry of Health and Welfare, Executive Yuan, 161-2 Kunyang St., Nangang Dist., Taipei 11561, Taiwan.

Fragrances are the most common chemicals in cosmetics to which people expose every day. However, the unwanted allergic reactions such as contact dermatitis caused by direct contact with fragrances may happen. In Directive 2003/15/EC of the EU, cosmetic product containing one or more of 26 fragrance allergens must be declared on the package label. Read More

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December 2021

Practical suggestions to improve standardization of repeated open application testing (ROAT) for daily use products.

Postepy Dermatol Alergol 2022 Apr 20;39(2):304-306. Epub 2021 Jan 20.

Amanza Skin Clinic, India.

Introduction: Repeated open application testing (ROAT) is an important adjuvant in the evaluation of allergic contact dermatitis. There are variations in the way ROAT is used by practitioners and standardizing the method, in terms of the area and amount of the antigen applied, could help improve the validity of the process.

Aim: Our study attempts to address ways in which part of the ROAT technique can be standardized - with respect to the area and amount of application and validation of the same through consensus opinion. Read More

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Is occupational asthma caused by low-molecular-weight chemicals associated with contact dermatitis? A retrospective study.

J Allergy Clin Immunol Pract 2022 May 25. Epub 2022 May 25.

Centre for Environment and Health, Department of Public Health and Primary Care, University of Leuven, Leuven, Belgium. Electronic address:

Background: Occupational asthma (OA) may have different etiologies, but it is not clear whether the etiologic agents influence the clinical presentation, especially the co-occurrence of skin lesions.

Objective: The aim of this study was to determine the impact of different asthmagens on the characteristics of OA, with a focus on the occurrence of prior or concomitant skin disorders.

Methods: In a retrospective analysis of patients who visited the Occupational and Environmental Disease Clinic of a tertiary referral hospital from 2009 to 2019, we classified patients into definite, probable or possible OA according to prespecified diagnostic guidelines. Read More

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The benefit of scratch patch testing to demonstrate ocular contact allergy to brimonidine tartrate.

Contact Dermatitis 2022 May 31. Epub 2022 May 31.

Department of Medicine, Division of Dermatology, Hôtel-Dieu de Québec, Université Laval, Québec, Canada.

Introduction: Ocular allergies to brimonidine are frequent in patients treated for glaucoma. There is variability in reporting due to the lack of diagnostic criteria and the absence of cutaneous testing. Many false-negative patch tests (PT) have been described. Read More

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Contact dermatitis in children caused by diabetes devices.

Contact Dermatitis 2022 May 30. Epub 2022 May 30.

Department of Dermatology and Venereology, Aarhus University Hospital, Aarhus, Denmark.

Background: Insulin pumps and glucose monitoring devices improve diabetes mellitus control and enhance patients' quality of life. However, a growing number of adverse cutaneous reactions related to the use of these devices have been reported.

Objective: To investigate the culprits of localized contact dermatitis in paediatric patients with diabetes caused by insulin pumps and glucose monitoring devices. Read More

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Preclinical Efficacy of a Capsid Virus-like Particle-Based Vaccine Targeting IL-1β for Treatment of Allergic Contact Dermatitis.

Vaccines (Basel) 2022 May 23;10(5). Epub 2022 May 23.

Centre for Medical Parasitology, Department for Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.

Hypersensitivity to a contact allergen is one of the most abundant forms of inflammatory skin disease. Today, more than 20% of the general population are sensitized to one or more contact allergens, making this disease an important healthcare issue, as re-exposure to the allergen can initiate the clinical disease termed allergic contact dermatitis (ACD). The current standard treatment using corticosteroids is effective, but it has side effects when used for longer periods. Read More

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Spreading Allergic Contact Dermatitis to Tea Tree Oil in an Over-the-Counter Product Applied on a Wart.

Medicina (Kaunas) 2022 Apr 19;58(5). Epub 2022 Apr 19.

Section of Dermatology, Department of Biomedical Science and Human Oncology, University of Bari, 70124 Bari, Italy.

Tea tree oil is an essential oil obtained by distillation from the leaves and terminal branchlets of and is now present in numerous products for body care and self-medication. We report a case of allergic contact dermatitis to tea tree oil in a young man who was applying a lotion containing tea tree oil on a wart localized on the plantar aspect of the right big toe, which had previously been treated with cryotherapy. He developed a severe eczematous eruption on the right foot and the right leg, with subsequent id reactions affecting the right thigh, the contralateral lower limb, the trunk and the upper limbs. Read More

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Keratinocytes: An Enigmatic Factor in Atopic Dermatitis.

Cells 2022 05 19;11(10). Epub 2022 May 19.

Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER)-Kolkata, Chunilal Bhawan, 168 Maniktala Main Road, Kolkata 700054, West Bengal, India.

Atopic dermatitis (AD), characterized by rashes, itching, and pruritus, is a chronic inflammatory condition of the skin with a marked infiltration of inflammatory cells into the lesion. It usually commences in early childhood and coexists with other atopic diseases such as allergic rhinitis, bronchial asthma, allergic conjunctivitis, etc. With a prevalence rate of 1-20% in adults and children worldwide, AD is gradually becoming a major health concern. Read More

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Inhibitory Effect of Sulfated Polysaccharide from P.C. Silva Against 2,4-Dinitrofluorobenzene (DNFB)- Induced Allergic Contact Dermatitis on Female BALB/c Mice.

Adv Pharm Bull 2022 Mar 6;12(2):410-418. Epub 2021 Feb 6.

The Graduate School, University of Santo Tomas, Manila, Philippines.

Sulfated polysaccharide from species has been reported for its antiinflammatoryactivities. However, the effect of sulfated polysaccharide from on allergic responses has not been studied. The study was conducted to determine the effect ofsulfated polysaccharide (F1) from C. Read More

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Impact of trends in new and emerging contact allergens.

Int J Womens Dermatol 2022 Mar 25;8(1):e006. Epub 2022 Mar 25.

Department of Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.

Allergic contact dermatitis represents a T cell-mediated, delayed-type hypersensitivity response to exogenous agents. While allergic contact dermatitis is one of the most common causes of skin disease encountered by dermatologists, emerging trends within the field are in constant flux, as influenced by ever-changing industry practices and evolving consumer behaviors. Although certain allergens continue to predominate, new chemicals are frequently being introduced, thus shifting the pattern of allergen exposure and sensitization. Read More

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Clinically relevant update on allergens!

Ann Allergy Asthma Immunol 2022 Jun;128(6):615-616

Division of Allergy and Immunology, Department of Pediatrics, Nationwide Children's Hospital - The Ohio State University College of Medicine, Columbus, Ohio. Electronic address:

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