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    15404 results match your criteria Contact Dermatitis Allergic

    1 OF 309

    Allergic contact reaction to antiseptics in very young children.
    J Eur Acad Dermatol Venereol 2018 Jun 19. Epub 2018 Jun 19.
    Department of Adult and Pediatric Dermatology, Bordeaux University Hospitals, France.
    Background: Contact dermatitis from topical antiseptic use has been reported mostly in adults but rare cases of chlorhexidine contact dermatitis have also been described in young children.

    Objective: To evaluate contact allergic dermatitis to antiseptics in young children.

    Methods: The children mostly referred for a misdiagnose (cellulitis) were patch tested with a selection of the European baseline series, an antiseptics series and the personal topical products used. Read More

    [Occupational allergic contact dermatitis: the role of occupational physician in the prevention.]
    G Ital Med Lav Ergon 2017 Nov;39(3):182-184
    Unità Clinico Operativa di Medicina del Lavoro - Università di Trieste.
    Objectives: Occupational contact dermatitis are the second occupational diseases in industrialized countries and the preventive action and/or early diagnosis done by occupational physician (OP) is of paramount importance.

    Methods: OP in the process of risk evaluation must suggest products, detergents and personal protective equipment with low irritant or sensitization potential. During work, the use of skin creams has to be promoted to prevent irritation that is the first step towards impairment of the skin barrier and sensitization. Read More

    Pediatric Inpatient and Emergency Dermatology Consultations: A 5-Year Retrospective Analysis.
    P R Health Sci J 2018 Jun;37(2):105-109
    Department of Dermatology, University of Puerto Rico Medical Sciences Campus, San Juan, PR.
    Objective: To characterize and analyze the inpatient and emergency pediatric dermatology consults in our academic hospital center.

    Methods: We reviewed 485 consultations that were done by the University of Puerto Rico Department of Dermatology from July 2007 to June 2012. The date, patient age and gender, consulting service, presumptive diagnosis, final diagnosis, and diagnostic procedures performed were documented for each consult. Read More

    Anti-pruritic and anti-inflammatory effects of oxymatrine in a mouse model of allergic contact dermatitis.
    J Dermatol Sci 2018 May 31. Epub 2018 May 31.
    Guangdong Province Key Laboratory of Pharmacodynamic New Drugs Research College of Pharmacy Jinan University Guangzhou 510632 Guangdong, China. Electronic address:
    Background: Allergic contact dermatitis (ACD) is a highly prevalent inflammatory disease of the skin. As a result of the complex etiology in ACD, therapeutic compounds targeting refractory pruritus in ACD lack efficacy and lead to numerous side effects.

    Objective: In this study, we investigated the anti-pruritic effects of oxymatrine (OMT) and explored its mechanism of action in a mouse model of ACD. Read More

    Glove-Related Allergic Contact Dermatitis.
    Dermatitis 2018 Jan/Feb;29(1):13-21
    Hand dermatitis is a common condition with a lifetime prevalence of 20%. Glove allergic contact dermatitis (ACD) is a very important dermatitis affecting health care workers, hairdressers, cleaning personnel, kitchen workers, craftsmen, construction workers, laboratory workers, and homemakers. Occupationally related cases may be severe and can result in significant disability. Read More

    Aggregate consumer exposure to isothiazolinones via household care and personal care products: Probabilistic modelling and benzisothiazolinone risk assessment.
    Environ Int 2018 Jun 9;118:245-256. Epub 2018 Jun 9.
    Institute for Chemical and Bioengineering, ETH Zürich, Zürich, Switzerland.
    Consumers regularly use household care and personal care products (HC&PCPs). Isothiazolinones are included in HC&PCPs as preservatives and are being held responsible for an epidemic rise in allergic contact dermatitis (ACD). The objective of this study was to assess the origin and extent of dermal exposure in order to evaluate the risk of ACD from isothiazolinones in HC&PCP. Read More

    The role of skin barrier in occupational contact dermatitis.
    Exp Dermatol 2018 Jun 12. Epub 2018 Jun 12.
    Coronel Institute of Occupational Health, Amsterdam Public Health Research Institute, Academic Medical Center, University of Amsterdam, 1105 AZ, Amsterdam, The Netherlands.
    Skin diseases represent one of the most common work-related diseases and may have a detrimental effect on social, personal and occupational aspects of life. Contact dermatitis, which comprises predominately irritant contact dermatitis (ICD) and allergic contact dermatitis (ACD) accounts for vast majority of occupational skin diseases, especially in occupations associated with frequent skin contact with irritants and contact allergens. Although ICD and ACD have similar clinical manifestation, their pathophysiology and the role of the skin barrier is different. Read More

    Possible Roles of Basophils in Chronic Itch.
    Exp Dermatol 2018 Jun 12. Epub 2018 Jun 12.
    Department of Dermatology and Cutaneous Surgery, Miami Itch Center, University of Miami Miller School of Medicine, Miami, FL, USA.
    Basophils are blood granulocytes and normally constitute less than 1% of blood peripheral leukocytes. Basophils share some morphological and functional similarities with mast cells, and basophils were once regarded as redundant and negligible circulating mast cells. However, recent studies reveal the indispensable roles of basophils in various diseases, including allergic and pruritic diseases. Read More

    Health impact assessment of a skin sensitizer: Analysis of potential policy measures aimed at reducing geraniol concentrations in personal care products and household cleaning products.
    Environ Int 2018 Jun 8;118:235-244. Epub 2018 Jun 8.
    National Institute for Public Health and the Environment, Centre for Safety of Substances and Products, Bilthoven, The Netherlands.
    A methodology to assess the health impact of skin sensitizers is introduced, which consists of the comparison of the probabilistic aggregated exposure with a probabilistic (individual) human sensitization or elicitation induction dose. The health impact of potential policy measures aimed at reducing the concentration of a fragrance allergen, geraniol, in consumer products is analysed in a simulated population derived from multiple product use surveys. Our analysis shows that current dermal exposure to geraniol from personal care and household cleaning products lead to new cases of contact allergy and induce clinical symptoms for those already sensitized. Read More

    Allergic contact dermatitis caused by acrylic-based medical dressings and adhesives.
    Contact Dermatitis 2018 Jun 11. Epub 2018 Jun 11.
    Department of Dermatology, University Hospitals KU Leuven, Leuven, Belgium.
    Background: Acrylates and methacrylates are acrylic resin monomers that are known to induce skin sensitization as a result of their presence in different materials, such as nail cosmetics, dental materials, printing inks, and adhesives. Allergic contact dermatitis resulting from the use of modern wound dressings containing them has only rarely been reported.

    Objectives: To describe 2 patients who developed allergic contact dermatitis caused by acrylic-based modern medical dressings and/or adhesives. Read More

    Is a specific eyelid patch test series useful? Results of a French prospective study.
    Contact Dermatitis 2018 Jun 8. Epub 2018 Jun 8.
    Department of Dermatology, CHU Montpellier, Montpellier, France.
    Background: Eyelids are frequent sites of contact dermatitis. No prospective study focused on eyelid allergic contact dermatitis (EACD) has yet been published, and this topic has never been studied in French patients.

    Objectives: To prospectively evaluate the usefulness of an eyelid series in French patients patch tested because of EACD, and to describe these patients. Read More

    Use of the LLNA:BrdU-ELISA for Skin Sensitization Hazard Assessment.
    Methods Mol Biol 2018 ;1803:101-116
    Cardiopulmonary and Immunotoxicology Branch, National Health and Environmental Effects Research Laboratory, Office of Research and Development, United States Environmental Protection Agency, Triangle Park, NC, USA.
    Allergic contact dermatitis (ACD) continues to be an occupational and environmental health issue. Consequently, there is a need to employ predictive tests to reduce the incidence of skin sensitization leading to clinical manifestations of ACD. For more than a decade, the murine local lymph node assay (LLNA) has been the method of choice for the identification of skin sensitizers. Read More

    Food-Related Contact Dermatitis, Contact Urticaria, and Atopy Patch Test with Food.
    Clin Rev Allergy Immunol 2018 Jun 7. Epub 2018 Jun 7.
    Department of Dermatology and Allergology, Ludwig Maximilian University, Munich, Frauenlobstr. 9-11, 80337, Munich, Germany.
    A wide variety of foods may cause or aggravate skin diseases such as contact dermatitis, contact urticaria, or atopic dermatitis (AD), both in occupational and private settings. The mechanism of action underlying allergic disease to food, food additives, and spices may be immunologic and non-immunologic. The classification and understanding of these reactions is a complex field, and knowledge of the possible reaction patterns and appropriate diagnostic test methods is essential. Read More

    [When sunscreens do not help: allergic contact dermatitis to UV filters].
    Hautarzt 2018 Jun 7. Epub 2018 Jun 7.
    Klinik für Hautkrankheiten, Universitätsklinikum Jena, Erfurter Str. 35, 07740, Jena, Deutschland.
    Ultraviolet (UV) filters may cause allergic and more frequently photoallergic contact dermatitis. Therefore, a photopach test should always be performed in case of a suspected contact sensitivity to UV filters. We report a case of a 65-year-old woman with a recurrent erythema of the face and décolleté after sun exposure despite application of a sunscreen. Read More

    Cinnamic acid derivatives in cosmetics - current use and future prospects.
    Int J Cosmet Sci 2018 Jun 5. Epub 2018 Jun 5.
    Department of Pharmaceutical Biochemistry, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9, Kraków, Poland.
    Cinnamic acid derivatives are widely used in cosmetics and possess various functions. This group of compounds includes both naturally occurring as well as synthetic substances. On the basis of the Cosmetic Ingredient Database (CosIng) and available literature, this review summarizes their functions in cosmetics, including their physicochemical and biological properties as well as reported adverse effects. Read More

    Cutaneous acceptability of a moisturizing cream in subjects with sensitive skin.
    J Cosmet Dermatol 2018 May 31. Epub 2018 May 31.
    GSK Consumer Healthcare, Weybridge, Surrey, UK.
    Background: Topical cosmetic products can cause adverse reactions in some individuals, particularly those with sensitive skin who may develop irritations or allergic contact dermatitis. Evidence suggests that the frequency of self-reported sensitive skin is increasing in the general population, placing greater importance on clinical testing of topical cosmetics for potential skin reactivity.

    Objectives: To confirm the cutaneous acceptability under normal conditions of use of a moisturizing cream in individuals with sensitive skin. Read More

    P-Phenylenediamine Hair Dye Allergy and Its Clinical Characteristics.
    Ann Dermatol 2018 Jun 23;30(3):316-321. Epub 2018 Apr 23.
    Department of Dermatology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
    Background: P-phenylenediamine (PPD) has been identified as the most frequent contact sensitizer of hair dye and the clinical characteristics of hair dye contact allergy (HDCA) are diverse.

    Objective: The purpose of this study was to identify the clinical characteristics of HDCA and to assess the relationships between HDCA, exposure time to PPD and PPD positivity.

    Methods: We analyzed 105 patients with patch test-confirmed hair dye allergy who presented between July 2009 and March 2015. Read More

    Methylisothiazolinone contact allergy in Croatia: Epidemiology and course of disease following patch testing.
    Contact Dermatitis 2018 May 30. Epub 2018 May 30.
    National Allergy Research Centre, Department of Dermatology and Allergy, Herlev Gentofte Hospital, University of Copenhagen, Hellerup, Denmark.
    Background: Methylisothiazolinone (MI) caused an epidemic of contact allergy in Europe, as shown by data from many countries, but no studies from Croatia exist. Also, data are lacking on the severity of allergic contact dermatitis (ACD) caused by MI, and its impact on quality of life and prognosis.

    Objectives: To determine the frequency of MI contact allergy among Croatian dermatitis patients, identify causative exposures, assess the impact of disease, and study the prognosis. Read More

    Solvent Orange 60 is a potent contact sensitizer in occupational and everyday life.
    Contact Dermatitis 2018 May 30. Epub 2018 May 30.
    Department of Occupational and Environmental Dermatology, Lund University, Skane University Hospital, Malmö, Sweden.
    Background: Solvent Orange (SO) 60 is a perinone-type dye that is often used in plastic materials such as spectacle frames and has been shown to cause contact allergy. The first case of SO 60 allergic contact dermatitis caused by spectacle frames was reported in 1999, and the second in 2011. We have recently seen 10 patients, of whom 6 developed dermatitis in the retroauricular/temporal area after wearing plastic spectacles. Read More

    Contact Allergy: A Review of Current Problems from a Clinical Perspective.
    Int J Environ Res Public Health 2018 May 29;15(6). Epub 2018 May 29.
    Department of Dermatology and Allergy, National Allergy Research Centre, Copenhagen University Hospital Herlev and Gentofte, 2900 Hellerup, Denmark.
    Contact allergy is common, affecting 27% of the general population in Europe. Original publications, including case reports, published since 2016 (inclusive) were identified with the aim of collating a full review of current problems in the field. To this end, a literature search employing methods of systematic reviewing was performed in the Medline and Web of Science™ databases on 28 January 2018, using the search terms ("contact sensitization" or "contact allergy"). Read More

    Contact dermatitis to training toilet seat (potty seat dermatitis).
    Pediatr Dermatol 2018 May 29. Epub 2018 May 29.
    Department of Dermatology, Penn State/Hershey Medical Center, Hershey, PA, USA.
    Allergic contact dermatitis from various components of toilet seats has been well described. We report a case of a young boy presenting with an atypical pattern of dermatitis who was found to be allergic to his training toilet seat. This case highlights the importance of recognizing this diagnosis and the role of potty seats as the causative factor. Read More

    Silkworm dropping extract ameliorate trimellitic anhydride-induced allergic contact dermatitis by regulating Th1/Th2 immune response.
    Biosci Biotechnol Biochem 2018 May 26:1-8. Epub 2018 May 26.
    a Food Biotechnology Program , Korea University of Science and Technology , Republic of Korea.
    Allergic contact dermatitis (ACD) is an inflammatory skin disease caused by hapten-specific immune response. Silkworm droppings are known to exert beneficial effects during the treatment of inflammatory diseases. Here, we studied whether topical treatment and oral administration of silkworm dropping extract (SDE) ameliorate trimellitic anhydride (TMA)-induced ACD. Read More

    Allergy to acrylate in composite in an orthodontic patient: a case report.
    J Orthod 2018 May 28:1-7. Epub 2018 May 28.
    a Orthodontic Department , Leeds Dental Institute , Leeds , UK.
    Acrylate allergies have been reported in dental professionals as a result of repeat exposure to various acrylate monomers and in dental patients with removable prostheses or longstanding composite restorations. To date, there is only one report of an allergic reaction in a young patient from small volumes of resin-based orthodontic adhesive. This case report demonstrates a recent case of gingival inflammation and lip oedema attributed to an acrylate allergy arising from the composite adhesive used with fixed appliances. Read More

    A retrospective study on titanium sensitivity: Patch test materials and manifestations.
    Contact Dermatitis 2018 May 24. Epub 2018 May 24.
    Department of Dermatology, VU University Medical Centre, Amsterdam, The Netherlands.
    Background: Titanium is being increasingly used. Although it is considered to be a non-allergenic material, allergic reactions to it have been reported. Titanium dioxide has been found to be an unreliable patch test material. Read More

    Beneficial Effects of Antioxidant Furfuryl Palmitate in Non-pharmacologic Treatments (Prescription Emollient Devices, PEDs) for Atopic Dermatitis and Related Skin Disorders.
    Dermatol Ther (Heidelb) 2018 May 22. Epub 2018 May 22.
    Dipartimento di Scienze biomediche, chirurgiche e odontoiatriche, Clinica Dermatologica, Università degli Studi di Milano, Milan, Italy.
    Introduction: Atopic dermatitis (AD) is a common chronic inflammatory skin disease; it requires long-term treatments focused on symptomatic relief. Current first-line treatments include moisturizers and topical corticosteroids. Recently, topical antioxidants have been added to moisturizer formulations to alleviate mild-to-moderate AD. Read More

    Skin lesions over the pocket area that may mimic cardiac implantable electronic device infection: A case series.
    Pacing Clin Electrophysiol 2018 May 21. Epub 2018 May 21.
    Arrhythmia Device and Electrophysiology Laboratory, University Hospital of Ioannina, Ioannina, Greece.
    Background: The early and correct diagnosis of cardiac implantable electronic device (CIED) infections is critical given that early aggressive treatment with complete removal of the system along with antimicrobial therapy dramatically improves outcomes. Pocket infection manifested by local signs of inflammation is the most common form of CIED infections. Conditions mimicking pocket infection have been described in the literature. Read More

    Activation of Herpes Simplex Infection after Tattoo.
    Acta Dermatovenerol Croat 2018 Apr;26(1):75-76
    Antigona Begolli Gerqari, MD, Dermatovenerology Clinic, University Clinical Center 10000 Pristina , Republic of Kosovo;
    Tattooing is a procedure where ink is applied to an area of the skin, mostly intraepidermally (1). This procedure is carried out mainly for aesthetic purposes. Lately, it has been used as a corrective medical procedure following amputation of mammilla. Read More

    Orthopedic and Cutaneous Reactions to Nickel after Total Hip Replacement.
    Acta Dermatovenerol Croat 2018 Apr;26(1):39-43
    Assist. Prof. Zrinjka Paštar, MD, PhD, Department of Health Studies , University of Zadar , Splitska 1 , 23000 Zadar, Croatia;
    Implant degradation products have shown signs of a cutaneous allergic response after implantation of a metal orthopedic replacement, loosening and failure of the joints as well as skin rashes, general fatigue, pain, and impaired wounds and bone healing. The prevalence of contact skin sensitivity in patients with a joint replacement device is higher than that in the general population. This delayed hypersensitivity to metallic orthopedic implants is more clearly defined and is a contributing factor to implant failure. Read More

    Janus Kinase Inhibitors: A Review of Their Emerging Applications in Dermatology
    Skin Therapy Lett 2018 05;23(3):5-9
    Division of Dermatology, University of Calgary, Calgary, AB, Canada.
    The class of medications known as Janus kinase inhibitors block cytokine-mediated signaling via the Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway, which plays an important role in immunoregulation and normal cell growth. This class includes the drugs tofacitinib, approved for the treatment of rheumatoid arthritis, and ruxolitinib, approved for the treatment of myelofibrosis and polycythemia rubra vera. The most common adverse events (AEs) reported in patients taking tofacitinib are infections, whereas the most common AEs in patients taking ruxolitinib are anemia and thrombocytopenia. Read More

    Systemic Contact Dermatitis.
    Clin Rev Allergy Immunol 2018 May 15. Epub 2018 May 15.
    Division of Rheumatology, Allergy & Immunology, NYU Winthrop University Hospital, 120 Mineola Blvd, Suite 410, Mineola, NY, 11501, USA.
    Systemic contact dermatitis (SCD) traditionally refers to a skin condition where an individual who is cutaneously sensitized to an allergen will subsequently react to that same allergen or a cross reacting allergen via a different route. It occurs to allergens including metals, medications, and foods. The exact pathophysiology underlying this disease remains unknown, although it appears to be mediated by type 4 hypersensitivity reactions and possibly type 3 hypersensitivity reactions. Read More

    Testing of Disposable Protective Garments Against Isocyanate Permeation From Spray Polyurethane Foam Insulation.
    Ann Work Expo Health 2018 May 12. Epub 2018 May 12.
    Department of Public Health, University of Massachusetts Lowell, One University Avenue, Lowell, MA, USA.
    Background: Diisocyanates (isocyanates), including methylene diphenyl diisocyanate (MDI), are the primary reactive components of spray polyurethane foam (SPF) insulation. They are potent immune sensitizers and a leading cause of occupational asthma. Skin exposure to isocyanates may lead to both irritant and allergic contact dermatitis and possibly contribute to systemic sensitization. Read More

    Occupational Contact Dermatitis in the Canadian Aircraft Industry.
    Dermatitis 2018 May/Jun;29(3):139-150
    From the Division of Dermatology, Department of Medicine, McGill University Health Centre, Montreal General Hospital, Québec, Canada.
    Background: Aircraft building exposes workers to irritant and sensitizing products.

    Objective: The aim of this article was to study occupational dermatoses among aircraft workers over 25 years.

    Methods: The files of aerospace workers referred between 1990 and 2015 were extracted from the database of the McGill University Health Centre contact dermatitis clinic. Read More

    Urushiol Patch Test Using the T.R.U.E. TEST System.
    Dermatitis 2018 May/Jun;29(3):127-131
    Department of Dermatology, Penn State Hershey Medical Center.
    Background: Poison ivy, poison oak, and poison sumac are the most common causes of allergic contact dermatitis in North America. Although extensive efforts have been made to develop therapies that prevent and treat allergic contact dermatitis to these plants, there lacks an entirely effective method, besides complete avoidance. Efforts to develop a more effective preventive therapy, such as a vaccine, are ongoing. Read More

    The Unique Molecular Signatures of Contact Dermatitis and Implications for Treatment.
    Clin Rev Allergy Immunol 2018 May 12. Epub 2018 May 12.
    Department of Dermatology and the Laboratory of Inflammatory Skin Diseases, Icahn School of Medicine at Mount Sinai Medical Center, 5 E. 98th Street, New York, NY, 10029, USA.
    Irritant contact dermatitis (ICD) and allergic contact dermatitis (ACD) are common skin disorders that are characterized by inflammation, oozing, crusting, and pruritus. Atopic dermatitis (AD) is an inflammatory skin disease characterized by immune and barrier abnormalities and is additionally a risk factor for acquiring ICD and ACD. New work on allergic sensitization to common allergens (e. Read More

    Stanniocalcin-2 contributes to mesenchymal stromal cells attenuating murine contact hypersensitivity mainly via reducing CD8 Tc1 cells.
    Cell Death Dis 2018 May 10;9(5):548. Epub 2018 May 10.
    The Biotherapy Center, the Third Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-Sen University, 510630, Guangzhou, China.
    Mesenchymal stromal cells (MSCs) have been demonstrated to ameliorate allergic contact dermatitis (ACD), a typical T-cell-mediated disorder. However, the underlying mechanisms behind the MSC-based treatment for ACD have not yet been fully elucidated. The stanniocalcins (STCs) comprise a family of secreted glycoprotein hormones that act as important anti-inflammatory proteins. Read More

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