15,949 results match your criteria Contact Dermatitis Allergic


A preliminary study of an alternative method for evaluating skin sensitizing potential of chemicals.

Int J Cosmet Sci 2019 Apr 16. Epub 2019 Apr 16.

Department of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, Pavia, Italy.

The skin, being a barrier between the human body and the environment, is exposed to a series of exogenous chemicals and physical factors. Allergic contact dermatitis (ACD) is one of the most common inflammatory skin diseases that occurs in the general population with a prevalence of 20% [1]. The inflammatory condition is induced by a single or multiple exposure to chemical substances, called haptens, which activate the innate immunity (irritative contact dermatitis) or both innate and acquired immunity (allergic contact dermatitis) [2]. Read More

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http://dx.doi.org/10.1111/ics.12530DOI Listing
April 2019
1 Read

Repeat patch testing in a patient with allergic contact dermatitis improved on dupilumab.

JAAD Case Rep 2019 Apr 3;5(4):336-338. Epub 2019 Apr 3.

Department of Dermatology, Stanford University School of Medicine, Redwood City, California.

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https://linkinghub.elsevier.com/retrieve/pii/S23525126193003
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http://dx.doi.org/10.1016/j.jdcr.2019.01.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447730PMC
April 2019
7 Reads

Patch Testing in Allergic Contact Dermatitis over the Lower Extremities.

Indian J Dermatol 2019 Mar-Apr;64(2):164

Department of Dermatology, Venereology and Leprology, JSS Medical College, JSS Academy of Higher Education and Research, Mysore, Karnataka, India.

Background: There is an increased incidence of allergic contact dermatitis (ACD) over the lower extremities due to over-the-counter topical preparations, occupational risk, and usage of several chemicals in the manufacture of designer footwear.

Aims And Objectives: The aim of the study was to identify the common allergens and polysensitization pattern involved in ACD over the lower extremities.

Materials And Methods: It is a cross-sectional study, wherein a total of 80 patients were recruited over a period of 18 months. Read More

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http://www.e-ijd.org/text.asp?2019/64/2/164/254171
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http://dx.doi.org/10.4103/ijd.IJD_759_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440194PMC
April 2019
2 Reads

Acetylation Phenotype Variation in Patients with Allergic Contact Dermatitis.

Indian J Dermatol 2019 Mar-Apr;64(2):164

Department of Dermatology, Al-Kadhimiya Teaching Hospital, Baghdad, Iraq.

Background: Studies have been done on acetylation phenotype in different diseases but not with allergic contact dermatitis (ACD).

Patients And Methods: Thirty-five ACD patients and 67 healthy volunteers were enrolled in the study. After an overnight fast, each participant received a single oral dose of 100 mg of dapsone. Read More

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http://www.e-ijd.org/text.asp?2019/64/2/164/254166
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http://dx.doi.org/10.4103/ijd.IJD_58_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440188PMC
April 2019
2 Reads

CCL2/CCR2 signaling elicits itch- and pain-like behavior in a murine model of allergic contact dermatitis.

Brain Behav Immun 2019 Apr 11. Epub 2019 Apr 11.

Department of Anesthesiology, Yale University School of Medicine, New Haven, CT 06510, USA. Electronic address:

Spontaneous itch and pain are the most common symptoms in various skin diseases, including allergic contact dermatitis (ACD). The chemokine (C-C motif) ligand 2 (CCL2, also referred to as monocyte chemoattractant protein 1 (MCP-1))and its receptor CCR2 are involved in the pathophysiology of ACD, but little is known of the role of CCL2/CCR2 for the itch- and pain-behaviors accompanying the murine model of this disorder, termed contact hypersensitivity (CHS). C57BL/6 mice previously sensitized to the hapten, squaric acid dibutyl ester, applied to the abdomen were subsequently challenged twice with the hapten delivered to either the cheek or to the hairy skin of the hind paw resulting in CHS at that site. Read More

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http://dx.doi.org/10.1016/j.bbi.2019.04.026DOI Listing
April 2019
2 Reads

An overview of herbal alternatives in androgenetic alopecia.

J Cosmet Dermatol 2019 Apr 13. Epub 2019 Apr 13.

Dr. Bhanuben, Nanavati College of Pharmacy, Mumbai, India.

The second most common alopecia-Androgenetic alopecia (AGA)-occurs due to hormonal imbalance. Dihydrotestosterone (DHT) an androgenic hormone is a sex steroid, produced in the gonads. The target sites of DHT are similar to that of testosterone, and it attaches easily remaining bound for 53 minutes as compared to 35 minutes of testosterone. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/jocd.12930
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http://dx.doi.org/10.1111/jocd.12930DOI Listing
April 2019
3 Reads

Changing Trends of Contact Allergens in Thailand: A 12-Year Retrospective Study.

Contact Dermatitis 2019 Apr 12. Epub 2019 Apr 12.

Department of Dermatology, Faculty of Medicine Siriraj Hospital Mahidol University, Bangkok, Thailand.

Background: Contact allergen prevalences often change. Continual surveillance is necessary to detect trends in sensitisation rates and emerging allergens.

Objective: To identify the prevalence of, and trends in, the positive reactions of each allergen in the baseline series during a 12-year period in Thailand. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/cod.13289
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http://dx.doi.org/10.1111/cod.13289DOI Listing
April 2019
2 Reads

Systemic allergic dermatitis after patch testing with dibucaine and topical corticosteroids.

Contact Dermatitis 2019 Apr 12. Epub 2019 Apr 12.

Department of Dermatology and Allergy Centre, Odense University Hospital, University of Southern Denmark, Odense, Denmark.

Systemic allergic dermatitis arises if an individual sensitised via the skin is exposed to the same allergen or a cross reacting allergen by a different route . It is rarely elicited by cutaneous contact with an allergen , although transepidermal rechallenge has been reported . We report a case of systemic allergic dermatitis caused by patch testing. Read More

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http://dx.doi.org/10.1111/cod.13290DOI Listing
April 2019
1 Read

Occupational Allergic Contact Dermatitis in Thai Spa Therapists.

Contact Dermatitis 2019 Apr 8. Epub 2019 Apr 8.

Institute of Dermatology, Bangkok, Thailand.

Occupational allergic contact dermatitis (ACD) in spa therapists is common and can result in sick leave, change in occupation and impaired quality of life.(1) Spa products frequently contain fragrance chemicals which are added to obtain the desired aroma.(2) Whilst it is recognized that sensitization to fragrance chemicals can occur in aromatherapists. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/cod.13288
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http://dx.doi.org/10.1111/cod.13288DOI Listing
April 2019
5 Reads

Airborne allergic contact dermatitis caused by Machaerium scleroxylon: confirmation by in vivo and in vitro tests.

Contact Dermatitis 2019 Apr 8. Epub 2019 Apr 8.

Section of Clinical, Allergological and Venereological Dermatology, Department of Medicine, University of Perugia, Italy.

Airborne agents can cause several skin reactions in occupational and less frequently in non-occupational settings, due to their strong irritant and/or sensitizing properties (1). Airborne allergic contact dermatitis is frequently caused by woods (2), above all tropical and subtropical woods containing many strong contact allergens, such as quinones (3). A case of airborne allergic contact dermatitis caused by Machaerium (M. Read More

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http://dx.doi.org/10.1111/cod.13287DOI Listing
April 2019
10 Reads

African blackwood (Dalbergia melanoxylon) induced occupational allergic contact dermatitis in a professional piccolo flautist.

Contact Dermatitis 2019 Apr 7. Epub 2019 Apr 7.

Department of Dermatology and Allergy Unit, Turku University Hospital and University of Turku, Turku, Finland.

African blackwood (Dalbergia melanoxylon) also known as mpingo or grenadilla is a small dry climate African tree with grey bark and very dense red to black core wood. It is part of the genus Dalbergia and is distinct from ebony that involves many different species in the genus Diospyros. This article is protected by copyright. Read More

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http://dx.doi.org/10.1111/cod.13285DOI Listing
April 2019
1 Read

Contact granulomatous hypersensitivity to indium in a patient with orofacial granulomatosis.

Contact Dermatitis 2019 Apr 7. Epub 2019 Apr 7.

Division of Dermatology, Tokushima Red Cross Hospital, Tokushima, Japan.

Indium-induced allergic granulomas have never been reported to date. Herein, we describe a case of orofacial granulomatosis (OFG), where sarcoidal-type granulomas developed at a patch test site of indium chloride. This article is protected by copyright. Read More

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http://dx.doi.org/10.1111/cod.13284DOI Listing
April 2019
1 Read

Localised bullous pemphigoid overlying knee arthroplasty: a diagnostic challenge.

BMJ Case Rep 2019 Apr 5;12(4). Epub 2019 Apr 5.

Department of Surgery, Arrowe Park Hospital, Wirral, UK.

An elderly Caucasian woman developed bullous pemphigoid (BP) overlying the site of total knee arthroplasty for osteoarthritis 2 days after surgery. The clinical findings were consistent with blistering due to soft tissue swelling, bullous impetigo or allergic contact dermatitis. The blistering spread over weeks to months down the ipsilateral leg and then to the other leg and hips. Read More

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http://dx.doi.org/10.1136/bcr-2018-227440DOI Listing
April 2019
5 Reads

Allergic contact dermatitis in patients with atopic dermatitis: A retrospective study.

J Allergy Clin Immunol Pract 2019 Apr 5. Epub 2019 Apr 5.

Department of Health Sciences, University of Catanzaro "Magna Graecia," Catanzaro, Italy.

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http://dx.doi.org/10.1016/j.jaip.2019.03.045DOI Listing
April 2019
2 Reads

Impact of Allergic Contact Dermatitis on the Quality of Life and Work Productivity.

Dermatol Res Pract 2019 3;2019:3797536. Epub 2019 Mar 3.

Occupational Medicine Department, Teaching Hospital Farhat Hached Sousse, Tunisia.

Background: Allergic contact dermatitis (ACD) is a common chronic skin disease that generates considerable public-health and socioeconomic costs. This disease affects the quality of life and the occupational activity of patients.

Aims: To assess the quality of life (QOL) of patients with ACD and study the impact of this disease on their work productivity. Read More

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http://dx.doi.org/10.1155/2019/3797536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421021PMC
March 2019
1 Read

Another source of allergic contact dermatitis to isothiazolinones in children-urgent call for regulation.

J Eur Acad Dermatol Venereol 2019 Mar 29. Epub 2019 Mar 29.

Dermatology Department, Coimbra University Hospital, Coimbra, Portugal.

Allergic contact dermatitis (ACD) from isothiazolinones is frequent and following an epidemic sensitization their use in leave-on products in Europe was forbidden and restricted that in rinse-off cosmetics, with a consequent decrease in the frequency of new cases in Europe, but still not evident in Portugal. Although more common in adults, methylchloroisothiazolinone (MCI) and methylisothiazolinone (MI) are also prevalent paediatric contact sensitizers. This article is protected by copyright. Read More

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http://dx.doi.org/10.1111/jdv.15602DOI Listing
March 2019
1 Read

Contact allergy to Tinuvin 770, a hindered amine light stabilizer in sandals contributing to hyperkeratotic foot dermatitis.

Contact Dermatitis 2019 Mar 28. Epub 2019 Mar 28.

National Institute of Technology and Evaluation (NITE) - Biological Resource Center, Shibuya-ku, Tokyo, Japan.

Tinuvin 770 (bis(2,2,6,6-tetramethyl-4-piperidyl) sebacate; BTMPS) is a hindered amine light stabilizer (HALS) used to prevent deterioration and discoloration of polymer compounds. We herein report the first case of allergic contact dermatitis caused by Tinuvin 770. This article is protected by copyright. Read More

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http://dx.doi.org/10.1111/cod.13279DOI Listing
March 2019
2 Reads

Th9 Cells in Allergic Disease.

Curr Allergy Asthma Rep 2019 Mar 26;19(5):29. Epub 2019 Mar 26.

Department of Medical Technology, Faculty of Allied Health Sciences, Thammasat University, Pathumthani, 12120, Thailand.

Purposes Of Review: Th9 cells are recognized as a novel subset of effector T helper cells that preferentially produce IL-9. Here, we provide a current update on the reports related to the function of Th9 cells in allergic inflammatory diseases.

Recent Findings: The effector Th9 cells differentiating from naïve T helper cells have recently been identified. Read More

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http://dx.doi.org/10.1007/s11882-019-0860-8DOI Listing
March 2019
3 Reads

Allergic contact dermatitis caused by oxidized linalool in a deodorant.

Contact Dermatitis 2019 Mar 26. Epub 2019 Mar 26.

Stockholm University, Department of Environmental Science and Analytical Chemistry, Stockholm, Sweden.

Linalool hydroperoxides (LinOOHs) frequently cause fragrance contact allergy (1-3). However, to our knowledge, there is only one case of dermatitis reported related to a scented product containing LinOOHs confirmed with chemical analysis (4). This article is protected by copyright. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/cod.13276
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http://dx.doi.org/10.1111/cod.13276DOI Listing
March 2019
5 Reads

RARE BURN CASES TREATED TRADITIONALLY: FOLK MEDICINE: REVIEW OF 8 CASES.

J Burn Care Res 2019 Mar 25. Epub 2019 Mar 25.

University of Health Sciences Gazi Yaşargil Training and Research Hospital, Diyarbakır, Anesthesiology.

The most common burn injuries in the Turkish population are scalding (traditional Turkish tea, hot milk, liquid food, etc.), electricity and chemical agents. However, many plants that are used as herbal medicine can also cause adverse effects such as allergic contact dermatitis and burns. Read More

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http://dx.doi.org/10.1093/jbcr/irz048DOI Listing
March 2019
2 Reads

Amorphous silicon dioxide nanoparticles modulate immune responses in a model of allergic contact dermatitis.

Sci Rep 2019 Mar 25;9(1):5085. Epub 2019 Mar 25.

Department of Environmental Medicine, University of Rochester Medical Center, New York, USA.

Amorphous silicon dioxide nanoparticles (SiNPs) are ubiquitous, and they are currently found in cosmetics, drugs, and foods. Biomedical research is also focused on using these nanoparticles as drug delivery and bio-sensing platforms. Due to the high potential for skin exposure to SiNPs, research into the effect of topical exposure on both healthy and inflammatory skin models is warranted. Read More

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http://dx.doi.org/10.1038/s41598-019-41493-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434075PMC
March 2019
1 Read

Fragrance inhalation and adverse health effects: The question of causation.

Regul Toxicol Pharmacol 2019 Jun 21;104:151-156. Epub 2019 Mar 21.

Faculty of Biology, Medicine and Health, University of Manchester, Manchester, M13 9PT, UK.

The toxicology of fragrance materials is largely well understood. Although most are benign, a minority have the potential to cause adverse health effects, notably allergic contact dermatitis resulting from skin sensitization. As a consequence, industry guidelines have banned certain materials and strictly limited the use of others. Read More

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http://dx.doi.org/10.1016/j.yrtph.2019.03.011DOI Listing
June 2019
1 Read

Allergic contact dermatitis caused by benzisothiazolinone in a continuous positive airway pressure mask liquid soap.

Contact Dermatitis 2019 Mar 23. Epub 2019 Mar 23.

Occupational Dermatology Research and Education Centre, The Skin and Cancer Foundation Inc., Carlton, Victoria, Australia.

As important allergens methylisothiazolinone (MI) and methylchloroisothiazolinone (MCI) are removed from products, their replacements, including other isothiazolinones, may emerge as significant allergens. We report a case of allergic contact dermatitis of the hands to benzisothiazolinone (BIT) after exposure to a liquid soap and a dishwashing concentrate. This article is protected by copyright. Read More

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http://dx.doi.org/10.1111/cod.13273DOI Listing
March 2019
2 Reads

Cosmetics for neonates and infants: haptens in products' composition.

Clin Transl Allergy 2019 8;9:15. Epub 2019 Mar 8.

Department of Pediatric Pneumology and Allergy, The Medical University of Warsaw, Żwirki i Wigury 63A, 02-091 Warsaw, Poland.

Cosmetics and skin care products for neonates and infants are considered as ''hypoallergenic'', "tested" or ''safe''. Nevertheless, the prevalence of haptens in these products is a matter of concern, since allergic contact dermatitis in children is gaining an importance. We aimed to assess the prevalence of haptens in cosmetics designed for children younger than 1 year. Read More

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http://dx.doi.org/10.1186/s13601-019-0257-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407239PMC
March 2019
1 Read

Don't forget the sponge.

Contact Dermatitis 2019 Mar 20. Epub 2019 Mar 20.

Department of Dermatology, Brigham and Women's Hospital, Chestnut Hill, Massachusetts.

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http://dx.doi.org/10.1111/cod.13270DOI Listing
March 2019
4 Reads

Allergic contact dermatitis caused by synthetic rubber gloves in healthcare workers: Sensitization to 1,3-diphenylguanidine is common.

Contact Dermatitis 2019 Mar 20. Epub 2019 Mar 20.

Department of Dermatology, Cliniques universitaires Saint-Luc, Brussels, Belgium and IREC (Institut de Recherche Experimentale et Clinique) Pôle Pneumologie, ORL, Dermatologie, Université Catholique de Louvain, Brussels, Belgium.

Background: The frequency of allergic contact dermatitis has significantly increased in healthcare workers since the transition from latex to synthetic rubber gloves, with 1,3-diphenylguanidine being identified as the most frequently implicated allergen.

Objectives: To highlight the role of 1,3-diphenylguanidine as the culprit allergen in contact allergies to synthetic rubber gloves, to propose recommendations for patch testing, and to discuss alternatives for sensitized subjects.

Materials And Methods: Patch test data from healthcare workers who developed hand dermatitis after wearing rubber gloves and who reacted positively to glove samples and rubber additives were collected from September 2010 to December 2017 in a Belgian hospital. Read More

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http://dx.doi.org/10.1111/cod.13269DOI Listing
March 2019
3 Reads

Allergic contact dermatitis to phenylbenzimidazole sulfonic acid included in a sunscreen.

Contact Dermatitis 2019 Mar 20. Epub 2019 Mar 20.

Department of Dermatology, Hospital Universitario del Henares, Coslada (Madrid), Spain.

Adverse reactions to sunscreens include allergic, irritant, phototoxic and photoallergic contact dermatitis (1). Allergic and photoallergic contact dermatitis to sunscreen may be caused by chemical ultraviolet (UV) absorbers, preservatives, perfumes, and other constituents. Photoallergic contact dermatitis reaction to UV absorbers is not common, and more frequent than allergic contact dermatitis. Read More

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http://dx.doi.org/10.1111/cod.13271DOI Listing
March 2019
2 Reads

Contact dermatitis due to transdermal therapeutic systems: a clinical update.

Acta Biomed 2018 Oct 26;90(1):5-10. Epub 2018 Oct 26.

Department of Biomedical Science and Human Oncology, Dermatological Clinic, University of Bari, Italy.

Transdermal therapeutic systems (TTS) have become a popular method of drug delivery because they allow drugs to be delivered in a rate-controlled manner, avoiding first-pass metabolism and the fluctuating plasma concentrations encountered with oral medications. Unfortunately, TTS may provoke adverse skin reactions as irritating contact dermatitis and allergic contact dermatitis: TTS seem to be ideally suited to produce sensitization because they cause occlusion, irritation, due to the repeated placement of the allergen in the same skin location. Since TTS consist of an adhesive, an active pharmaceutical drug and enhancing agents, sensitization may develop owing to one of these three agents. Read More

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http://dx.doi.org/10.23750/abm.v90i1.6563DOI Listing
October 2018
2 Reads

Evaluation of positive patch test reactions using optical coherence tomography: A pilot study.

Skin Res Technol 2019 Mar 19. Epub 2019 Mar 19.

Dr.Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA.

Introduction: Patch testing is the gold standard for evaluating allergic contact dermatitis (ACD), yet current interpretation methods are limited by their subjectivity and possible variability between observers. Optical coherence tomography (OCT) imaging enables noninvasive in vivo skin visualization and holds promise as an objective method of patch test interpretation.

Objective: To evaluate the micromorphological changes of patch test reactions and identify objective, quantitative OCT markers that correlate with clinically graded patch test reactions. Read More

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http://dx.doi.org/10.1111/srt.12695DOI Listing
March 2019
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The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects.

Eur J Epidemiol 2019 Mar 18;34(3):279-300. Epub 2019 Mar 18.

Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.

The impact of many unfavorable childhood traits or diseases, such as low birth weight and mental disorders, is not limited to childhood and adolescence, as they are also associated with poor outcomes in adulthood, such as cardiovascular disease. Insight into the genetic etiology of childhood and adolescent traits and disorders may therefore provide new perspectives, not only on how to improve wellbeing during childhood, but also how to prevent later adverse outcomes. To achieve the sample sizes required for genetic research, the Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia were established. Read More

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http://dx.doi.org/10.1007/s10654-019-00502-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447695PMC
March 2019
6 Reads
5.339 Impact Factor

Variable impact of dupilumab on patch testing results and allergic contact dermatitis in adults with atopic dermatitis.

J Am Acad Dermatol 2019 Mar 15. Epub 2019 Mar 15.

Department of Dermatology, Preventive Medicine and Medical Social Sciences, Feinberg School of Medicine at Northwestern University, Chicago, IL; Northwestern Medicine Multidisciplinary Eczema Center, Chicago, IL. Electronic address:

Background: Previous case reports/series suggested that dupilumab may be an effective treatment for allergic contact dermatitis (ACD). Little is known about the impact of dupilumab on patch test results and comorbid ACD in patients with atopic dermatitis (AD).

Objective: Determine the impact of dupilumab on patch testing results and improvement of ACD in AD patients. Read More

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http://dx.doi.org/10.1016/j.jaad.2019.03.020DOI Listing
March 2019
2 Reads

Plant Allergen-Induced Contact Dermatitis.

Planta Med 2019 Mar 15. Epub 2019 Mar 15.

Allergy Research Group, Department of Dermatology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Germany.

Although manifold beneficial effects of plant compounds for the treatment of skin disorders are known, cutaneous exposure to plants can also result in various types of incompatibility reactions such as contact dermatitis. In this mini-review, we briefly describe the different clinical forms of contact dermatitis (photoinduced, irritative, and allergic form) and highlight recent publications in the field of contact dermatitis. Major topics are recent recommendations regarding testing for plant contact dermatitis, advances in understanding the immunological mechanisms of plant contact dermatitis, and case reports for plant contact dermatitis. Read More

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http://dx.doi.org/10.1055/a-0873-1494DOI Listing
March 2019
4 Reads

"Slime" contact dermatitis: Case report and review of relevant allergens.

Pediatr Dermatol 2019 Mar 13. Epub 2019 Mar 13.

Department of Dermatology, Massachusetts General Hospital, Boston, Massachusetts.

Homemade "slime" is currently a popular childhood hobby that can cause allergic and irritant contact dermatitis. We describe a case of hand dermatitis due to homemade "slime" with a positive patch test to methylchloroisothiazolinone (MCI)/methylisothiazolinone (MI) and MI. The most common potential allergens in "slime" collected from a review of "slime" recipes found on the Internet are reviewed. Read More

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http://dx.doi.org/10.1111/pde.13792DOI Listing
March 2019
1 Read

Lichen sclerosus et atrophicus and allergic contact dermatitis: A significant association.

J Cosmet Dermatol 2019 Mar 12. Epub 2019 Mar 12.

Dermatology Unit, NESMOS Department, S. Andrea Hospital, University of Rome "Sapienza", Rome, Italy.

Lichen sclerosus et atrophicus (LSA) is a chronic inflammatory skin disease of unknown etiology. It mainly affects the anogenital area, while the extragenital involvement is uncommon. It manifests as pale, ivory-colored lesions and partially atrophic skin. Read More

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http://dx.doi.org/10.1111/jocd.12915DOI Listing
March 2019
4 Reads

Oral Nickel Changes of Intestinal Microflora in Mice.

Curr Microbiol 2019 May 11;76(5):590-596. Epub 2019 Mar 11.

Department of Allergy, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing Key Laboratory of Precision Medicine for Diagnosis and Treatment on Allergic Diseases, No. 1 Shuaifuyuan, East District, Beijing, 100730, People's Republic of China.

Nickel, a silver-colored metal found in nature, is a common cause of allergic contact dermatitis. Nevertheless, the existence of inflammatory reaction to oral nickel exposure remains controversial. The following study investigates whether oral nickel can change the intestinal microflora in mice. Read More

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http://dx.doi.org/10.1007/s00284-019-01664-1DOI Listing
May 2019
2 Reads
1.423 Impact Factor

Immunological characterization of onion () allergy.

Postepy Dermatol Alergol 2019 Feb 22;36(1):98-103. Epub 2019 Feb 22.

Department of Emergency and Organ Transplantation, School and Chair of Allergology and Clinical Immunology, University of Bari-Aldo Moro, Bari, Italy.

Introduction: Onion (Allium cepa) handling can induce contact dermatitis, rhinoconjunctivitis and asthma. However, only sporadic reports exist on allergic reactions to onion consumption.

Aim: We describe herein a case of a 35-year-old man who had an episode of anaphylaxis following cooked onion ingestion. Read More

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http://dx.doi.org/10.5114/ada.2019.82829DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409889PMC
February 2019

Experience in patch testing: A 6-year retrospective review from a single academic allergy practice.

Ann Allergy Asthma Immunol 2019 Mar 6. Epub 2019 Mar 6.

Division of Allergy and Immunology, Department of Medicine, Albany Medical College, Albany, NY. Electronic address:

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http://dx.doi.org/10.1016/j.anai.2019.02.028DOI Listing
March 2019
2 Reads

Blocking type 2 inflammation by dupilumab does not control classic (type 1-driven) allergic contact dermatitis in chronic hand eczema.

Contact Dermatitis 2019 Mar 9. Epub 2019 Mar 9.

EA 4064 , Épidémiologie environnementale: impact sanitaire des pollutions, Paris Descartes University, Paris, France.

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http://dx.doi.org/10.1111/cod.13266DOI Listing
March 2019
3 Reads

Allergic contact dermatitis caused by a Brazilian exotic hardwood.

Contact Dermatitis 2019 Mar 6. Epub 2019 Mar 6.

Department of Dermatology, Hospital das Clínicas of the University of São Paulo Medical School, São Paulo, Brazil.

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http://dx.doi.org/10.1111/cod.13259DOI Listing
March 2019
4 Reads

Evaluation of risk modification for para-phenylenediamine sensitization by N-acetyltransferase 1 and 2 for two highly sensitive cases.

Contact Dermatitis 2019 Mar 6. Epub 2019 Mar 6.

Department of Environmental Toxicology, Trier University, Trier, Germany.

p-Phenylenediamine (PPD, 1,4-diaminobenzene, CAS no. 106-50-3) is well known as key allergen in hair dye-related allergic contact dermatitis. PPD can be N-acetylated to the non-sensitizing compounds mono- (MAPPD) and diacetyl-PPD (DAPPD) by N-acetyltransferase 1 (NAT1) in keratinocytes , and outside the skin also by N-acetyltransferase 2 (NAT2). Read More

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http://dx.doi.org/10.1111/cod.13260DOI Listing
March 2019
2 Reads

Post-inflammatory depigmentation caused by Basic Blue 75.

Contact Dermatitis 2019 Mar 6. Epub 2019 Mar 6.

Department of Integrative Medical Science for Allergic Disease, Fujita Health University School of Medicine, Otobashi, Nakagawa-ku Nagoya, Aichi, Japan.

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http://dx.doi.org/10.1111/cod.13262DOI Listing
March 2019
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Myroxylon pereirae resin (Balsam of Peru)-A critical review of the literature and assessment of the significance of positive patch test reactions and the usefulness of restrictive diets.

Authors:
Anton C de Groot

Contact Dermatitis 2019 Mar 6. Epub 2019 Mar 6.

acdegroot publishing, Wapserveen, The Netherlands.

In this article, contact allergy to Myroxylon pereirae resin (MP) (balsam of Peru) is reviewed. The topics presented include the uses, the chemical composition, the frequency of sensitization, the relevance of positive reactions, the MP-containing products causing allergic contact dermatitis, co-reactivity with other fragrance and non-fragrance materials, the sensitizers, the usefulness of MP as a "marker" of fragrance allergy, and the effectiveness of and indications for "balsam-restrictive" diets. Sensitization to MP occurs in 4% to 8% of patients routinely tested for suspected contact dermatitis. Read More

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http://dx.doi.org/10.1111/cod.13263DOI Listing
March 2019
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Botulinum neurotoxin A is an effective treatment for irritant dermatitis caused by ostomy leaks in patients with retractile stomas.

Br J Dermatol 2019 Mar 6. Epub 2019 Mar 6.

Department of Dermatology, York Teaching Hospital Foundation Trust, York, YO31 8HE, United Kingdom.

Inflammatory or infectious conditions affecting the skin around a stoma occur in up to 73% of ostomates and can be associated with significant morbidity. Peristomal skin complications include dermatitis resulting from mechanical trauma, ICD, allergic contact dermatitis, infections and pyoderma gangrenosum. Peristomal dermatitis is most often caused by leakage of stool or urine that is irritant to the skin. Read More

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http://dx.doi.org/10.1111/bjd.17856DOI Listing
March 2019
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αEβ7 Expression Increases With the Extent of Cutaneous Involvement in Mycosis Fungoides.

Am J Dermatopathol 2019 Feb 28. Epub 2019 Feb 28.

Departments of Pathology, and.

Background: Cell adhesion molecules are essential to lymphocyte migration in neoplastic and inflammatory skin diseases. Our aim was to investigate possible differences in cell adhesion molecule expression between mycosis fungoides (MF) and inflammatory skin diseases (drug reactions and allergic contact dermatitis).

Methods: We selected 33 biopsies from patients with MF and 10 biopsies of patients with inflammatory skin diseases from Department of Pathology-Universidade Federal de São Paulo (UNIFESP) from January 1997 to December 2013. Read More

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http://dx.doi.org/10.1097/DAD.0000000000001397DOI Listing
February 2019
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Severe facial reaction to thiurams in surgeons

Med Pr 2019 Mar;70(1):121-124

University of Rome “Tor Vergata,” Rome, Italy (Department of Occupational Medicine)

Contact dermatitis is a major problem in the healthcare environment and in other sectors. Healthcare professionals may be exposed to a large number of chemical agents, including the accelerators for rubber vulcanization process. The prevalence of allergic contact dermatitis among operators in the sector ranges 13–30%. Read More

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http://dx.doi.org/10.13075/mp.5893.00738DOI Listing
March 2019
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Allergic contact dermatitis to chlorhexidine in pediatric patients.

Pediatr Dermatol 2019 Mar 5. Epub 2019 Mar 5.

Department of Dermatology, Hospital General Universitario de Valencia, Valencia, Spain.

Chlorhexidine is one of the most widely used antiseptics in our environment. Allergic contact dermatitis to chlorhexidine is common in adults, but is quite rare in the pediatric population. Its diagnosis is important because it can mimic other dermatoses common during childhood, and it can also lead to acute immediate hypersensitivity reactions following successive exposures. Read More

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http://dx.doi.org/10.1111/pde.13808DOI Listing
March 2019
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Allergic contact dermatitis caused by neem oil: An underrated allergen?

Contact Dermatitis 2019 Mar 4. Epub 2019 Mar 4.

Department of Biomedical Science and Human Oncology, Dermatological Clinic, University of Bari, Bari, Italy.

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http://dx.doi.org/10.1111/cod.13256DOI Listing
March 2019
3 Reads

Allergic contact dermatitis and electronic cigarettes: Is nickel to blame?

Contact Dermatitis 2019 Mar 4. Epub 2019 Mar 4.

Department of Dermatology, Centro Hospitalar Universitário do Porto, Porto, Portugal.

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http://dx.doi.org/10.1111/cod.13257DOI Listing
March 2019
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Anti-Inflammatory Effects of Cold Thermal Therapy on Allergic Skin Inflammation Induced by Trimellitic Anhydride in BALB/c Mice.

Mediators Inflamm 2019 28;2019:1936769. Epub 2019 Jan 28.

Department of Anatomy, Chonbuk National University Medical School, Jeonju, Jeonbuk 54896, Republic of Korea.

Cold and hot thermal therapies are widely used as a traditional therapy in many cultures and are often prescribed in the treatment of various musculoskeletal and neurological conditions which present themselves to primary care physicians. However, there are no reports that investigated either the effects of cold and hot thermal therapies on the skin inflammation of trimellitic anhydride- (TMA-) induced dermatitis-like contact hypersensitivity (CHS) mouse model, or the mechanism of thermal therapy on allergic skin inflammation. Therefore, in this study, to reveal the anti-inflammatory effect of thermal therapy and its mechanism on TMA-induced CHS, we analyzed ear-swelling response (ear edema), vascular permeability, serum IgE levels, histological examination, and histamine and Th2 cytokine levels. Read More

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http://dx.doi.org/10.1155/2019/1936769DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369506PMC
January 2019
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Airborne Allergic Contact Dermatitis: Management and Responsible Allergens on the American Contact Dermatitis Society Core Series.

Dermatitis 2019 Mar/Apr;30(2):106-115

Airborne allergic contact dermatitis occurs when allergen particles suspended in the air deposit on the skin. Many allergens can result in an airborne distribution if presented in an aerosolized form. This review summarizes the allergens in the American Contact Dermatitis Society Core Allergen Series that have been documented to cause airborne allergic contact dermatitis. Read More

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http://dx.doi.org/10.1097/DER.0000000000000439DOI Listing
March 2019
2 Reads