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    14854 results match your criteria Contact Dermatitis Allergic

    1 OF 298

    Airborne allergic contact dermatitis caused by isothiazolinones in water-based paints: a retrospective study of 44 cases.
    Contact Dermatitis 2017 Apr 27. Epub 2017 Apr 27.
    Dermatology and Allergology Department, Tenon Hospital (AP-HP), Sorbonne Universities, UPMC University Paris 06, 75020, Paris, France.
    Background: Airborne allergic contact dermatitis caused by paints containing isothiazolinones has been recognized as a health hazard.

    Objectives: To collect epidemiological, clinical and patch test data on airborne allergic contact dermatitis caused by isothiazolinone-containing paints in France and Belgium.

    Methods: A descriptive, retrospective study was initiated by the Dermatology and Allergy Group of the French Society of Dermatology, including methylchloroisothiazolinone (MCI)/methylisothiazolinone (MI)- and/or MI-sensitized patients who developed airborne allergic contact dermatitis following exposure to isothiazolinone-containing paint. Read More

    Cl(-) channel is required for CXCL10-induced neuronal activation and itch response in a murine model of allergic contact dermatitis.
    J Neurophysiol 2017 Apr 26:jn.00187.2017. Epub 2017 Apr 26.
    Yale School of Medicine.
    Persistent itch often accompanies allergic contact dermatitis (ACD), but the underlying mechanisms remain largely unexplored. We previously demonstrated that CXCL10/ CXCR3 signaling activated a subpopulation of cutaneous primary sensory neurons and mediated itch response after contact hypersensitivity (CHS), a murine model of ACD, induced by squaric acid dibutylester. The purpose of this study was to determine the ionic mechanisms underlying CXCL10-induced neuronal activation and allergic itch. Read More

    Screening allergic reactions to resol resin based on phenol and formaldehyde in a clinic of occupational dermatology.
    Contact Dermatitis 2017 Apr 25. Epub 2017 Apr 25.
    Occupational Medicine, Finnish Institute of Occupational Health (FIOH), 00250, Helsinki, Finland.
    Background: Allergic reactions to resol-type phenol formaldehyde resin [phenol formaldehyde resin 2 (PFR2)] are relatively common. It has been suggested that PFR2 should be included in baseline series. However, a recent international study found clinical relevance in only 25% of patients. Read More

    Contact sensitizers trigger human CD1-autoreactive T-cell responses.
    Eur J Immunol 2017 Apr 25. Epub 2017 Apr 25.
    Singapore Immunology Network, Agency for Science, Technology and Research, Singapore.
    Allergic contact dermatitis is a primarily T-cell-mediated inflammatory skin disease induced by exposure to small molecular-weight haptens, which covalently bind to proteins. The abundance of cutaneous T cells that recognize CD1a antigen-presenting molecules raises the possibility that MHC-independent antigen presentation may be relevant in some hapten-driven immune responses. Here we examine the ability of contact sensitizers to influence CD1-restricted immunity. Read More

    Garlic Dermatitis on the Neck of an Infant Treated for Nasal Congestion.
    Pediatr Dermatol 2017 Apr 19. Epub 2017 Apr 19.
    Division of Dermatology, Ann and Robert H. Lurie Children's Hospital of Chicago, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
    The health benefits of garlic (Allium sativum) as a naturopathic remedy have been well documented, but topical application of garlic has been linked to allergic and irritant contact dermatitis. We present a case of severe irritant contact dermatitis due to application of a fresh garlic necklace to the neck of infant for treatment of nasal congestion. Read More

    A multi-institutional joint study of contact dermatitis related to hair colouring and perming agents in Japan.
    Contact Dermatitis 2017 Apr 20. Epub 2017 Apr 20.
    Department of Dermatology, Fujita Health University School of Medicine, Toyoake, 470-1100, Japan.
    Background: In Japan, allergic contact dermatitis caused by hair colouring agents is a considerable problem for those occupationally exposed and also for consumers. Over the last 20 years, p-phenylenediamine (PPD) has been a common allergen, with ∼7% positive patch test reactions.

    Objectives: To investigate which ingredients caused allergic contact dermatitis related to hair dye and perming solutions in Japan, to assess whether PPD is suitable for screening for hair dye allergy, and to propose allergens for a Japanese hairdresser series. Read More

    An epidemic of allergic contact dermatitis caused by a new allergen, caprylhydroxamic acid, in moisturizers.
    Contact Dermatitis 2017 Apr 19. Epub 2017 Apr 19.
    Department of Dermatology and Allergy Centre, Tampere University Hospital, 33520, Tampere, Finland.
    Background: In 2016, dermatologists in Finland suspected contact allergy in several patients using moisturizers under the trade name Apobase®. Following a formulation change, Phenostat™, which is a mixture of phenoxyethanol, caprylhydroxamic acid, and methylpropanediol, was used as a preservative in Apobase® moisturizers in Finland.

    Objectives: To confirm the suspected contact allergy to Apobase® cream, oily cream, and/or lotion, and to identify the specific contact allergen and define its optimal patch test concentration. Read More

    Myths on Chemical Burns in the Diaper Area.
    Clin Pediatr (Phila) 2017 May;56(5_suppl):13S-15S
    1 Kenwood Dermatology, Cincinnati, OH, USA.
    Over the past several years, a number of articles and online posts have circulated on the Internet associating use of disposable and cloth diapers with chemical burns on babies' skin. Because both mild chemical burns and diaper dermatitis (diaper rash) can cause skin redness and peeling, it is not surprising that some confusion has arisen regarding the association between these two conditions. However, diapers cannot cause chemical burns because they are made of inert materials. Read More

    Differential Diagnosis of Diaper Dermatitis.
    Clin Pediatr (Phila) 2017 May;56(5_suppl):16S-22S
    1 Johns Hopkins Children's Center, Baltimore, MD, USA.
    Mild diaper dermatitis often occurs in children before toilet training is complete, particularly from 9 to 12 months of age, and the most common presentation is an irritant contact dermatitis. Diaper dermatitis may account for up to 25% of dermatology visits to health care providers during the first year of life. Fortunately, since the introduction of hypoallergenic, superabsorbent modern disposable diapers, the incidence and severity of irritant and allergic contact dermatitis has decreased dramatically. Read More

    Temporary Black Henna Tattoos and Sensitization to para-Phenylenediamine (PPD): Two Paediatric Case Reports and a Review of the Literature.
    Int J Environ Res Public Health 2017 Apr 14;14(4). Epub 2017 Apr 14.
    Pediatric Clinic, Università degli Studi di Perugia, 06129 Perugia, Italy.
    Background: The use of temporary henna tattoos has increased dramatically in recent years, especially in children and adolescents. To obtain a darker colour and prolong the life of the tattoo, red henna, a plant-derived substance, is typically added to para-phenylenediamine (PPD). The mixture is called temporary black henna tattoo (TBHT). Read More

    [Epicutaneous patch testing in delayed drug hypersensitivity reactions induced by antiepileptic drugs].
    Therapie 2017 Mar 25. Epub 2017 Mar 25.
    Centre régional de pharmacovigilance de Sfax, faculté de médecine de Sfax, avenue Majida-Boulila, 3029 Sfax, Tunisie.
    Introduction: Antiepileptic drugs are widely used and are associated with numerous side effects including skin eruptions. Epicutaneous tests have been used with variable success in skin drug reactions. The purpose of this study was to evaluate the profitability of epicutaneous tests in delayed hypersensitivity reactions induced by antiepileptic drugs. Read More

    Chemokine Receptor CXCR3 in the Spinal Cord Contributes to Chronic Itch in Mice.
    Neurosci Bull 2017 Apr 11. Epub 2017 Apr 11.
    Pain Research Laboratory, Institute of Nautical Medicine, Jiangsu Key Laboratory of Neuroregeneration, Nantong University, Nantong, 226019, China.
    Recent studies have shown that the chemokine receptor CXCR3 and its ligand CXCL10 in the dorsal root ganglion mediate itch in experimental allergic contact dermatitis (ACD). CXCR3 in the spinal cord also contributes to the maintenance of neuropathic pain. However, whether spinal CXCR3 is involved in acute or chronic itch remains unclear. Read More

    Metals Are Important Contact Sensitizers: An Experience from Lithuania.
    Biomed Res Int 2017 16;2017:3964045. Epub 2017 Mar 16.
    Clinic of Infectious and Chest Diseases, Dermatovenereology and Allergology, Centre of Pulmonology and Allergology, Vilnius University, Vilnius, Lithuania.
    Background. Metals are very frequent sensitizers causing contact allergy and allergic contact dermatitis worldwide; up-to-date data based on patch test results has proved useful for the identification of a problem. Objectives. Read More

    [Allergic contact dermatitis of the scalp].
    Hautarzt 2017 Apr 10. Epub 2017 Apr 10.
    Univ. Klinik für Dermatologie und Venerologie, Medizinische Universität Graz, Auenbruggerplatz 8, 8036, Graz, Österreich.
    Contact allergy represents an important differential diagnosis to other skin diseases of the scalp. The typical efflorescences, spreading in the periphery, pruritus, and the clinical history support the differential diagnosis. Since the scalp is particularly resistant to contact dermatitis, allergens applied to this area often produce dermatitis of the eyelids, ears and neck. Read More

    Survey of Occupational Allergic Contact Dermatitis and Patch Test among Clothing Employees in Beijing.
    Biomed Res Int 2017 15;2017:3102358. Epub 2017 Mar 15.
    Department of Dermatology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.
    Occupational population-based epidemiological data relating to occupational contact allergies in the Chinese clothing industry are limited. To investigate the prevalence of occupational allergic contact dermatitis (OACD) and to identify the causative allergens among clothing employees in China, a cross-sectional study was conducted in 529 clothing employees at 12 clothing factories in Beijing. All employees were subjected to an interview using self-administered questionnaire and skin examination, and those who were diagnosed with occupational contact dermatitis (OCD) were patch tested. Read More

    Surgery-Related Contact Dermatitis: A Review of Potential Irritants and Allergens.
    J Allergy Clin Immunol Pract 2017 Apr 7. Epub 2017 Apr 7.
    Division of Allergy, Asthma and Immunology, Scripps Clinic, San Diego, Calif.
    Surgical procedures utilize an increasing number of medical products including antiseptics, anesthetics, gloves, suture materials, tissue adhesives, topical antibiotics, and bandages. Many of these products have irritant potential. Allergic contact dermatitis has also been reported. Read More

    Occupational Contact Dermatitis in North American Production Workers Referred for Patch Testing: Retrospective Analysis of Cross-sectional Data From the North American Contact Dermatitis Group 1998 to 2014.
    Dermatitis 2017 Apr 7. Epub 2017 Apr 7.
    From the *HCMC Parkside Occupational and Contact Dermatitis Clinic; †Department of Dermatology, Minneapolis Veterans Affairs Medical Center; and ‡Department of Dermatology, University of Minnesota Medical School, Minneapolis, MN; §Division of Dermatology, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada; ∥Dartmouth-Hitchcock Medical Center, Lebanon, NH; ¶Division of Dermatology, Royal Victoria Hospital, McGill University, Montreal, Quebec, Canada; #Department of Dermatology, Columbia University, New York, NY; **Ohio State University, Columbus; ††University of Louisville, KY; ‡‡Department of Dermatology, Cleveland Clinic, OH; §§Associates in Dermatology, Fort Myers, FL; ∥∥Department of Dermatology, Keck School of Medicine at University of Southern California, Los Angeles; ¶¶Department of Dermatology, Pennsylvania State University, State College; ##Division of Dermatology, University of Ottawa, Ontario, Canada; ***Department of Dermatology, University of California, San Francisco; and †††Department of Dermatology, University of Cincinnati, OH.
    Background: Little is known about the epidemiology of contact dermatitis in production workers (PWs).

    Objective: The aims of this study were to estimate the prevalence of contact dermatitis and characterize clinically relevant and occupationally related allergens among North American PWs undergoing patch testing.

    Methods: This was a retrospective cross-sectional analysis of North American Contact Dermatitis Group data from 1998 to 2014. Read More

    Association between atopic dermatitis and contact sensitization: A systematic review and meta-analysis.
    J Am Acad Dermatol 2017 Apr 6. Epub 2017 Apr 6.
    Department of Dermatology and Allergy, Herlev and Gentofte Hospital, University of Copenhagen, Hellerup, Denmark; National Allergy Research Centre, Department of Dermatology and Allergy, Herlev and Gentofte Hospital, University of Copenhagen, Hellerup, Denmark.
    Background: It is unclear whether patients with atopic dermatitis (AD) have an altered prevalence or risk for contact sensitization. Increased exposure to chemicals in topical products together with impaired skin barrier function suggest a higher risk, whereas the immune profile suggests a lower risk.

    Objective: To perform a systematic review and meta-analysis of the association between AD and contact sensitization. Read More

    Nickel allergy in a Danish population 25 years after the first nickel regulation.
    Contact Dermatitis 2017 Apr 7. Epub 2017 Apr 7.
    Department of Dermatology and Allergy, National Allergy Research Centre, Herlev and Gentofte Hospital, University of Copenhagen, 2900, Hellerup, Denmark.
    Background: Nickel in metallic items has been regulated in Denmark since 1990; however, 10% of young Danish women are still sensitized to nickel. There is a need for continuous surveillance of the effect of regulation.

    Objectives: To identify current self-reported metallic exposures leading to dermatitis in nickel-allergic patients, and the minimum contact time needed for dermatitis to occur. Read More

    Stratum corneum profiles of inflammatory mediators in patch test reactions to common contact allergens and sodium lauryl sulfate.
    Br J Dermatol 2016 Nov 4. Epub 2016 Nov 4.
    Coronel Institute of Occupational Health, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105AZ, Amsterdam, the Netherlands.
    Background: Recent studies have demonstrated allergen-specific differences in the gene expression of inflammatory mediators in patch tested skin.

    Objectives: To determine levels of various inflammatory mediators in the stratum corneum (SC) after patch testing with common contact allergens and the skin irritant sodium lauryl sulfate (SLS).

    Methods: In total, 27 individuals who had previously patch tested positive to nickel, chromium, methylchloroisothiazolinone/methylisothiazolinone (MCI/MI) or para-phenylenediamine were retested and then patch tested with SLS and petrolatum, with petrolatum serving as the patch test control. Read More

    (Meth)Acrylate Occupational Contact Dermatitis in Nail Salon Workers.
    J Cutan Med Surg 2017 Mar 1:1203475417701420. Epub 2017 Mar 1.
    2 Division of Occupational Medicine, Department of Medicine, St Michael's Hospital, Toronto, ON, Canada.
    Background: Recently, many cases of acrylate-associated allergic contact dermatitis have appeared among nail salon workers. Common acrylate-containing products in nail salons include traditional nail polish, ultraviolet-cured shellac nail polish, ultraviolet-cured gel nails, and press-on acrylic nails.

    Methods: Nail salon technicians seen in the occupational medicine clinic in 2015 and 2016 were identified, and their patch test results and clinical features were summarized. Read More

    Hybrid optimal descriptors as a tool to predict skin sensitization in accordance to OECD principles.
    Toxicol Lett 2017 Mar 27. Epub 2017 Mar 27.
    IRCCS, Istituto di Ricerche Farmacologiche Mario Negri, 20156, Via La Masa 19, Milano, Italy.
    Skin sensitization (allergic contact dermatitis) is a widespread problem arising from the contact of chemicals with the skin. The detection of molecular features with undesired effect for skin is complex task owing to unclear biochemical mechanisms and unclearness of conditions of action of chemicals to skin. The development of computational methods for estimation of this endpoint in order to reduce animal testing is recommended (Cosmetics Directive EC regulation 1907/2006; EU Regulation, Regulation, 1223/2009). Read More

    Anti-Inflammatory Effect of Titrated Extract of Centella asiatica in Phthalic Anhydride-Induced Allergic Dermatitis Animal Model.
    Int J Mol Sci 2017 Mar 30;18(4). Epub 2017 Mar 30.
    College of Pharmacy and Medical Research Center, Chungbuk National University, 194-31 Osongsaengmyeong 1-ro, Osong-eup, Heungduk-gu, Cheongju 361-951, Korea.
    Centella asiatica has potent antioxidant and anti-inflammatory properties. However, its anti-dermatitic effect has not yet been reported. In this study, we investigated the anti-dermatitic effects of titrated extract of Centella asiatica (TECA) in a phthalic anhydride (PA)-induced atopic dermatitis (AD) animal model as well as in vitro model. Read More

    [Clinical effect of rock salt aerosol therapy in treatment of occupational allergic contact dermatitis].
    Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 2017 Feb;35(2):141-143
    The Second Hospital of Heilongjiang Province, Harbin 150010, China.
    Objective: To investigate the clinical effect and safety of rock salt aerosol therapy in the treatment of occupational allergic contact dermatitis. Methods: A total of 65 patients with acute exacerbation of occupational allergic contact dermatitis who were treated in the Outpatient Service and Inpatient Department of our hospital from March 2013 to December 2015 were enrolled and randomly divided into observation group and control group using a random number table. Both groups were givensymptomatic treatment including desensitization, and the patients in the observation group were given rock salt aerosol therapy for 2 courses in addition to the symptomatic treatment. Read More

    Debunking the Myth of Wool Allergy: Reviewing the Evidence for Immune and Non-immune Cutaneous Reactions.
    Acta Derm Venereol 2017 Mar 28. Epub 2017 Mar 28.
    Department of Dermatology, Monash University, Eastern Health, Box Hill Victoria; Murdoch Childrens Research Institute, Victoria, 3168 Melbourne, Australia.
    Although wool is commonly believed to cause irritant (non-immune) and hypersensitivity (immune) cutaneous reactions, the evidence basis for this belief and its validity for modern garments have not been critically examined. Publications from the last 100 years, using MEDLINE and Google Scholar, were analysed for evidence that wool causes cutaneous reactions, both immune-mediated (atopic dermatitis exacerbation, contact urticaria, allergic contact dermatitis) and non-immune-mediated (irritant contact dermatitis, itch). Secondary aims of this paper were to examine evidence that lanolin and textile-processing additives (formaldehyde, chromium) cause cutaneous reactions in the context of modern wool-processing techniques. Read More

    Evaluation of 4-methylcyclohexanemethanol (MCHM) in a combined irritancy and Local Lymph Node Assay (LLNA) in mice.
    Food Chem Toxicol 2017 Mar 22;105:99-105. Epub 2017 Mar 22.
    National Toxicology Program, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC, USA.
    4-Methylcyclohexanemethanol (MCHM) is a flotation reagent used in fine coal beneficiation. On January 9, 2014, crude MCHM, a mixture containing predominantly MCHM, was inadvertently released into the Elk River, a municipal water source that serves about 300,000 people in the Charleston, WV area, resulting in temporary contamination of 15 percent of the state's tap water and causing significant dermal exposure. The current studies were undertaken to determine whether crude MCHM or MCHM has the potential to produce dermal irritancy and/or sensitization. Read More

    Intestinal dendritic cell licensing through Toll-like receptor 4 is required for oral tolerance in patients with allergic contact dermatitis.
    J Allergy Clin Immunol 2017 Mar 22. Epub 2017 Mar 22.
    Mucosal Immunity, Vaccination & Biotherapies Laboratory, INSERM U1111-CNRS UMR5308, Université Claude Bernard Lyon 1, Ecole Normale Superieure de Lyon, Jouy-en-Josas, France. Electronic address:
    Background: Induction of oral tolerance to haptens is an efficient way to prevent allergic contact dermatitis (ACD) in mice. Toll-like receptor (TLR)-mediated sensing of the microbiota contributes to gut homeostasis, yet whether it contributes to induction of oral tolerance has not been documented.

    Objective: We examined whether oral tolerance to the contact sensitizer 2,4-dinitro-fluorobenzene (DNFB) depends on microbiota/TLRs and evaluated the role of TLR4 on the tolerogenic function of intestinal dendritic cells (DCs). Read More

    Clinical Study of 124 Patients Having Perianal Dermatitis.
    Dermatitis 2017 Mar 23. Epub 2017 Mar 23.
    From the Department of Dermatology, Complejo Hospitalario de Navarra, Pamplona, Spain.
    Background: Perianal complaints are often consulted in dermatology clinics, and in many cases, a conclusive diagnosis is not easily made.

    Objective: The aim of this study was to study and identify the epidemiological, clinical, and contact allergy features of patients with perianal dermatitis who attended at a contact dermatitis unit in a tertiary hospital in Spain.

    Methods: Adult patients with long-lasting (>4 weeks) perianal dermatitis were recruited during the past 10 years for investigation and follow-up. Read More

    Multicenter Patch Testing With Methylisothiazolinone and Methylchloroisothiazolinone/Methylisothiazolinone Within the International Contact Dermatitis Research Group.
    Dermatitis 2017 Mar 23. Epub 2017 Mar 23.
    From the *Department of Occupational and Environmental Dermatology, Skåne University Hospital, Lund University, Malmö, Sweden; †Allergy Center and Department of Dermatology, University Hospital, Republic University of Uruguay, Montevideo; ‡Department of Dermatology and Allergy Centre, Odense University Hospital, University of Southern Denmark; §Department of Dermatology, University Hospital Jena, Germany; ∥Department of Dermatology, National Skin Center, Singapore, Singapore; ¶Contact Allergy Unit, Department of Dermatology, University Hospital K.U. Leuven, Belgium; #Department of Dermatology, MGM Medical College, Navi Mumbai, India; **Department of Dermatology, Fujita Health University School of Medicine, Toyoake, Japan; and ††St John's Institute of Dermatology, Contact Dermatitis Clinic, St Thomas' Hospital, London, United Kingdom.
    Background: The preservatives methylchloroisothiazolinone/methylisothiazolinone (MCI/MI) and MI are well-known contact sensitizers. Recently, an increase in the contact allergy frequency for MI 0.2% aqueous (aq) has been seen in many European countries paralleled with an increase in MCI/MI allergy. Read More

    Intralesional Treatment With 5-Fluorouracil and Steroid Improves Allergic Contact Dermatitis Without Causing Skin Atrophy and Rebound Lesions.
    Dermatitis 2017 Mar 23. Epub 2017 Mar 23.
    Department of Dermatology, Shanghai Jiading Nanxiang Hospital, Shanghai, China School of Life Sciences, Shanghai University, China Department of Dermatology, Shanghai Pudong New District Zhoupu Hospital, Shanghai, China Department of Pediatric Endocrinology/Genetics, Xinhua Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai Institute for Pediatric Research, China Department of Dermatology, Nanxiang Hospital of Jiading District, Shanghai, China Department of Dermatology, Shanghai Jiading Nanxiang Hospital, Shanghai, China

    Occupational Contact Dermatitis in North American Print Machine Operators Referred for Patch Testing: Retrospective Analysis of Cross-Sectional Data From the North American Contact Dermatitis Group 1998 to 2014.
    Dermatitis 2017 Mar 23. Epub 2017 Mar 23.
    From the *HCMC Parkside Occupational and Contact Dermatitis Clinic and Department of Dermatology, Minneapolis Veterans Affairs Medical Center; and †Department of Dermatology, University of Minnesota Medical School, Minneapolis; ‡Department of Dermatology, Columbia University, New York, NY; §Division of Dermatology, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada; ∥Department of Dermatology, University of California San Francisco; ¶Department of Dermatology, University of Cincinnati, OH; #Dartmouth-Hitchcock Medical Center, Lebanon, NH; **Division of Dermatology, Royal Victoria Hospital, McGill University, Montreal, Quebec, Canada; ††Ohio State University, Columbus; ‡‡University of Louisville, KY; §§Associates in Dermatology, Fort Myers, FL; ∥∥Department of Dermatology, Keck School of Medicine at University of Southern California, Los Angeles; ¶¶Department of Dermatology, Pennsylvania State University, State College; ##Division of Dermatology, University of Ottawa, Ontario, Canada; and ***Department of Dermatology, Cleveland Clinic, OH.
    Background: Little is known about the epidemiology of contact dermatitis (CD) in print machine operators (PMOs).

    Objective: The aims of this study were to estimate the prevalence of CD and characterize clinically relevant and occupationally related allergens among PMOs undergoing patch testing.

    Methods: This was a retrospective cross-sectional analysis of the North American Contact Dermatitis Group data from 1998 to 2014. Read More

    Allergenic Ingredients in Facial Wet Wipes.
    Dermatitis 2017 Mar 23. Epub 2017 Mar 23.
    From the *University of Minnesota School of Medicine, Minneapolis; †Department of Dermatology, Minneapolis Veterans Affairs Medical Center, MN; ‡HCMC Parkside Occupational and Contact Dermatitis Clinic; and §Department of Dermatology, University of Minnesota, Minneapolis.
    Background: Allergic contact dermatitis commonly occurs on the face. Facial cleansing wipes may be an underrecognized source of allergens.

    Objective: The aim of this study was to determine the frequency of potentially allergenic ingredients in facial wet wipes. Read More

    Allergenic Ingredients in Personal Hygiene Wet Wipes.
    Dermatitis 2017 Mar 23. Epub 2017 Mar 23.
    From the *University of Minnesota School of Medicine; †Department of Dermatology, Minneapolis Veterans Affairs Medical Center; ‡HCMC Parkside Occupational and Contact Dermatitis Clinic; and §Department of Dermatology, University of Minnesota, Minneapolis.
    Background: Wet wipes are a significant allergen source for anogenital allergic contact dermatitis.

    Objective: The aim of the study was to calculate the frequency of potentially allergenic ingredients in personal hygiene wet wipes.

    Methods: Ingredient lists from brand name and generic personal hygiene wet wipes from 4 large retailers were compiled. Read More

    Prevention of poison ivy dermatitis with oral homeopathic Rhus toxicodendron.
    Dermatol Online J 2017 Jan 15;23(1). Epub 2017 Jan 15.
    Dermatology, Private Practice, Tinley Park, Illinois.
    Acute allergic contact dermatitis to poison ivy is acommon and miserable dermatosis which affectsmillions of Americans each year. Preventativemeasures, such as avoidance, protective clothing,barrier creams, soaps, and solvents often fail despiteour patients' best attempts. Severe allergic reactionsto poison ivy are a significant source of decreasedemployee productivity owing to inability to work anda major health care expenditure. Read More

    Prevalence and risk factors of contact dermatitis among clothing manufacturing employees in Beijing: A cross-sectional study.
    Medicine (Baltimore) 2017 Mar;96(12):e6356
    aDepartment of Dermatology, Beijing Friendship Hospital, Capital Medical University bDepartment of Dermatology, Beijing Aerospace General Hospital, Beijing, China.
    Little is known about the epidemiology of contact dermatitis (CD) in the Chinese clothing industry. This study aimed to investigate the prevalence and some risk factors of contact dermatitis among clothing manufacturing employees in Beijing.This cross-sectional study was conducted by interview using self-administered questionnaires and skin examination between May and August in 2016. Read More

    Skin sensitizers in cosmetics and beyond: potential multiple mechanisms of action and importance of T-cell assays for in vitro screening.
    Crit Rev Toxicol 2017 Mar 22:1-18. Epub 2017 Mar 22.
    a Cosmetics Division, Office of Cosmetics and Colors (OCAC) , Center for Food Safety and Applied Nutrition (CFSAN), Food and Drug Administration (FDA) , MD , USA.
    Allergic contact dermatitis (ACD) is a delayed-type hypersensitivity (DTH) reaction induced by repeated contact with sensitizers. The ability of a chemical to act as a sensitizer has most frequently been tested in animals. As the use of animals for these purposes is gradually and globally being phased out, there is a need for reliable in vitro surrogate assays. Read More

    Roles of alternatively activated M2 macrophages in allergic contact dermatitis.
    Allergol Int 2017 Mar 17. Epub 2017 Mar 17.
    Department of Allergy and Clinical Immunology, Graduate School of Medicine, Chiba University, Chiba, Japan.
    Alternatively activated macrophages (M2 macrophages) play key roles in the suppression of Th1 cell responses and the orchestration of tissue repair. However, recent studies have shown that M2 macrophages have potentials to produce high levels of proinflammatory cytokines such as IL-1β, IL-6, and TNF-α, suggesting that M2 macrophages may exacerbate inflammation in some settings. In this regard, we have recently shown that large numbers of M2 macrophages accumulate in the sites of hapten-induced contact hypersensitivity (CHS), an animal model of allergic contact dermatitis, and that M2 macrophages exacerbate hapten-induced CHS by producing matrix metalloproteinase 12 (MMP12). Read More

    Atopic Dermatitis in Israeli Adolescents from 1998 to 2013: Trends in Time and Association with Migraine.
    Pediatr Dermatol 2017 Mar 20. Epub 2017 Mar 20.
    Department of Dermatology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
    Background: Recent data have shown an increasing occurrence of atopic dermatitis (AD) in children and adolescents, as well as in adults. Most of the epidemiologic research on AD is limited to pediatric and youth populations and is based on self-reported questionnaires.

    Methods: A nationwide, population-based, cross-sectional retrospective study of adolescents with AD was performed to estimate its prevalence, trends, and association with demographic factors and comorbidities. Read More

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