42,117 results match your criteria Consciousness and Cognition [Journal]


Challenges and Demand for Modeling Disorders of Consciousness following Traumatic Brain Injury.

Neurosci Biobehav Rev 2018 Dec 11. Epub 2018 Dec 11.

Center for Brain Injury & Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States; Center for Neurotrauma, Neurodegeneration & Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA, United States; Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, United States. Electronic address:

Following severe traumatic brain injury (TBI), many patients experience coma - an unresponsive state lacking wakefulness or awareness. Coma rarely lasts more than two weeks, and emergence involves passing through a state of wakefulness without awareness of self or environment. Patients that linger in these Disorders of Consciousness (DoC) undergo clinical assessments of awareness for diagnosis into Unresponsive Wakefulness Syndrome (no awareness, also called vegetative state) or Minimally Conscious State (periodic increases in awareness). Read More

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December 2018

Don't go there - It's not a nice place: Older adults' experiences of delirium.

Int J Ment Health Nurs 2018 Dec 13. Epub 2018 Dec 13.

School of Nursing, University of Auckland, Auckland, New Zealand.

Delirium is a common neuropsychiatric disorder that causes fluctuations in consciousness and attention, impairments in cognitive functioning and information processing, and changes in how individuals perceive what is going on around them. Delirium is associated with increased mortality, ongoing impairment in cognitive functioning, and a high possibility of discharge to residential care. The experience of delirium may be distressing for the patient and their family. Read More

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December 2018

Cervical Spinal Cord Stimulation for the Vegetative State: A Preliminary Result of 12 Cases.

Neuromodulation 2018 Dec 13. Epub 2018 Dec 13.

Department of Neurosurgery, West China Hospital of Sichuan University, Chengdu, China.

Objectives: Data on the treatment of the vegetative state (VS) with cervical spinal cord stimulation (cSCS) are limited and prognostic factors are inconclusive. In this study, we present our experience of treating 12 VS patients with cSCS and discuss the prognostic factors.

Methods: Twelve VS patients were enrolled. Read More

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December 2018

Sensory coding is impaired in rat absence epilepsy.

J Physiol 2018 Dec 13. Epub 2018 Dec 13.

Univ. Grenoble Alpes, Grenoble Institut des Neurosciences, GIN, F-38000, Grenoble, France.

Key Points: Absence epilepsy is characterized by the occurrence of spike-and-wave discharges concomitant with an alteration of consciousness and associated with cognitive comorbidities. In a genetic model of absence epilepsy in the rat, the GAERS, we showed that spike-and-wave discharges are initiated in the barrel field primary somatosensory cortex that codes whisker-related information therefore playing an essential role in rodents' interactions with their environment. Sensory-information processing is impaired in the epileptic barrel field primary somatosensory cortex of GAERS with a delayed sensory-evoked potential and a duplicated neuronal response to whisker-stimulation in in vivo extracellular recordings. Read More

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December 2018

Altered frontal aslant tracts as a heritable neural basis of social communication deficits in autism spectrum disorder: A sibling study using tract-based automatic analysis.

Autism Res 2018 Dec 12. Epub 2018 Dec 12.

Institute of Medical Device and Imaging, National Taiwan University College of Medicine, Taipei, Taiwan.

Investigating social behaviors and brain structural alterations in unaffected siblings of individuals with autism spectrum disorder (ASD) may help identify intermediate phenotypes of social communication deficits in ASD. This study hypothesized that such intermediate phenotypes could be identified in white matter tracts of the social communication model that exhibited reduced tract integrity and associations with social communication deficits. Boys with ASD (N = 30), unaffected male siblings (N = 27), and typically developing (TD) boys (N = 30) underwent clinical evaluation and MRI scanning. Read More

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December 2018

A problem shared is a problem halved? Comparing burdens arising for family caregivers of patients with disorders of consciousness in institutionalized versus at home care.

BMC Psychol 2018 Dec 14;6(1):58. Epub 2018 Dec 14.

Department of Psychology, University of Bielefeld, Bielefeld, Germany.

Background: Disorders-of-consciousness (DOC) are rare conditions leading to very severe physical and mental disabilities. Providing care for DOC patients has been described as a stressful experience, eroding the physical and psychological health of the caregiver. Different forms of care may have different impacts on the caregivers and institutionalized care has been suggested to have an unburdening effect, but this possibility has never been empirically studied. Read More

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December 2018

Isolated ACTH deficiency presenting with severe myocardial dysfunction.

J Cardiol Cases 2011 Aug 15;4(1):e26-e30. Epub 2011 Jun 15.

Department of Internal Medicine, National Hospital Organization Kobe Medical Center, Kobe, Japan.

We present a case of isolated adrenocorticotropic hormone (ACTH) deficiency complicated by acute adrenal crisis and severe myocardial dysfunction. A 54-year-old woman developed consciousness disturbance, hypoglycemia, hyponatremia, and rhabdomyolysis. Initial echocardiographic examinations on the sixth hospital day revealed marked right-sided atrial and ventricular dilatation and severe tricuspid regurgitation. Read More

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Effective surgical treatment for controlling the acute heart failure induced by acutely progressed mitral regurgitation with nonbacterial thrombotic endocarditis.

J Cardiol Cases 2010 Oct 24;2(2):e59-e62. Epub 2010 Mar 24.

Department of Cardiovascular Medicine, Nantan General Hospital, 25, Yagi-Ueno, Yagi-cho, Nantan city, Kyoto 629-0197, Japan.

A 45-year-old woman complaining of consciousness disturbance demonstrated multiple brain infarctions. Echocardiogram showed vegetation on the posterior mitral leaflet. Infectious endocarditis was initially suspected and we started empirical antibiotics. Read More

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October 2010

A case of transient apical hypertrophy associated with coronary vasospasm.

J Cardiol Cases 2017 Jan 17;15(1):14-17. Epub 2016 Oct 17.

Division of Cardiovascular Medicine, Toho University Ohashi Medical Center, Tokyo, Japan.

A 49-year-old woman was admitted to our hospital because of repeated loss of consciousness. On arrival, she was in cardiopulmonary arrest associated with arrhythmia of Torsades de pointes, and recovered from it after cardiopulmonary resuscitation and defibrillation. The administration of a β-blocker and amiodarone was initiated to prevent ventricular tachycardia. Read More

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January 2017

Effects of Air Pollution Control on Urban Development Quality in Chinese Cities Based on Spatial Durbin Model.

Int J Environ Res Public Health 2018 Dec 11;15(12). Epub 2018 Dec 11.

School of Economics and Management, Harbin Institute of Technology, Harbin 150001, China.

With the rapid development of urbanization, industrialization, and motorization, a large number of Chinese cities have been affected by heavy air pollution. In order to promote the development quality of Chinese cities, mixed regulations to control air pollution have been implemented under the lead of government. The principal component analysis and efficacy coefficient method are used to estimate urban development quality, according to the panel data of 285 prefecture-level cities in China over the period 2003⁻2016. Read More

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December 2018

Cryptococcal meningitis in a multiple sclerosis patient treated with Fingolimod: a case report and review of imaging findings.

Clin Imaging 2018 Nov 14;54:53-56. Epub 2018 Nov 14.

Department of Radiology, Baylor College of Medicine, One Baylor Plaza, BCM 360, Houston, TX 77030, United States.

Fingolimod is an oral medication approved by the Food and Drug Administration in 2009 for the treatment of relapsing remitting multiple sclerosis (RRMS). Initial clinical trials did not show a significantly increased rate of serious infections with fingolimod therapy. However, a mildly increased risk of less serious infections, such as varicella zoster virus and herpes simplex virus, was reported. Read More

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November 2018

Dimensions of interoception predict premonitory urges and tic severity in Tourette syndrome.

Psychiatry Res 2018 Dec 6;271:469-475. Epub 2018 Dec 6.

Sackler Centre for Consciousness Science, University of Sussex, University Kingdom; Department of Neuroscience, Brighton & Sussex Medical School, United Kingdom; Sussex Partnership NHS Foundation Trust, United Kingdom.

Interoceptive processes in Tourette syndrome may foster the premonitory urges that commonly precede tics. Twenty-one adults with TS and 22 controls completed heartbeat tracking and discrimination tasks. Three dimensions of interoception were examined: objective accuracy, metacognitive awareness, and subjective (self-report) sensibility. Read More

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December 2018

Mechanisms of decreased cholinergic arousal in focal seizures: In vivo whole-cell recordings from the pedunculopontine tegmental nucleus.

Exp Neurol 2018 Dec 10. Epub 2018 Dec 10.

Departments of Neurology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA; Departments of Neuroscience, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA; Departments of Neurosurgery, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA. Electronic address:

Focal limbic seizures often impair consciousness/awareness with major negative impact on quality of life. Recent work has shown that limbic seizures depress brainstem arousal systems, including reduced action potential firing in a key node: cholinergic neurons of the pedunculopontine tegmental nucleus (PPT). In vivo whole-cell recordings have not previously been achieved in PPT, but are used here with the goal of elucidating the mechanisms of reduced PPT cholinergic neuronal activity. Read More

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December 2018

Private-sector investor's intention and motivation to invest in Land Degradation Neutrality.

PLoS One 2018 13;13(12):e0208813. Epub 2018 Dec 13.

Dialog N - Research and Communication for People, Environment and Nature, Uster, Switzerland.

Private-sector investors could be key players in combatting global land degradation and realising the emerging concept of Land Degradation Neutrality (LDN). To better understand how to incentivize private-sector investors for LDN, we conducted an online-survey of 68 private-sector investors. Structural equation modelling based on the theory of planned behavior was performed to investigate how cognitive, social, emotional, motivational and financial determinants influence their intention and motivation to invest in LDN. Read More

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December 2018

Consciousness in Neurocritical Care Cohort Study Using fMRI and EEG (CONNECT-ME): Protocol for a Longitudinal Prospective Study and a Tertiary Clinical Care Service.

Front Neurol 2018 27;9:1012. Epub 2018 Nov 27.

Department of Neurology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

To facilitate individualized assessment of unresponsive patients in the intensive care unit for signs of preserved consciousness after acute brain injury. Physicians and neuroscientists are increasingly recognizing a disturbing dilemma: Brain-injured patients who appear entirely unresponsive at the bedside may show signs of covert consciousness when examined by functional MRI (fMRI) or electroencephalography (EEG). According to a recent meta-analysis, roughly 15% of behaviorally unresponsive brain-injured patients can participate in mental tasks by modifying their brain activity during EEG- or fMRI-based paradigms, suggesting that they are conscious and misdiagnosed. Read More

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November 2018

Frequent lucid dreaming associated with increased functional connectivity between frontopolar cortex and temporoparietal association areas.

Sci Rep 2018 Dec 12;8(1):17798. Epub 2018 Dec 12.

Wisconsin Institute for Sleep and Consciousness Department of Psychiatry, University of Wisconsin, Madison, USA.

Humans typically lack awareness that they are dreaming while dreaming. However, at times a remarkable exception occurs and reflective consciousness can be regained while dreaming, referred to as lucid dreaming. While most individuals experience lucid dreams rarely there is substantial variance in lucid dream frequency. Read More

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December 2018

Multi-systemic melioidosis: a clinical, neurological, and radiological case study from Hainan Province, China.

BMC Infect Dis 2018 Dec 12;18(1):649. Epub 2018 Dec 12.

Department of Radiology, Hainan General Hospital, No. 19 Xiuhua Road, Xiuying District, Haikou, 570311, Hainan, People's Republic of China.

Background: Melioidosis is a tropical disease caused by Burkholderia pseudomallei (B. pseudomallei). It can infect any organ system and lead to multiple abscesses. Read More

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December 2018

Pituitary Metastasis in a Patient with Pulmonary Adenocarcinoma Presenting with a Disturbance of Consciousness.

Klin Onkol 2018 ;31(5):371-375

Background: Brain metastases are one of the main causes of morbidity and mortality of patients with oncological disease. In non-small cell lung carcinoma (NSCLC), the risk of CNS secondary development is 30-50%. An unusual diagnostic and therapeutic problem is the finding of suspicious pituitary lesions. Read More

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January 2018

[Feasibility of supraglottic tracheal tube ventilation during painless fiberbronchoscopy].

Zhonghua Yi Xue Za Zhi 2018 Dec;98(46):3767-3772

Department of Anesthesiology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China.

To evaluate the feasibility and safety of supraglottic tracheal tube ventilation by comparing with modified laryngeal mask airway ventilation during painless fiberbronchoscopy. This was a prospective study. Twenty-eight patients undergoing painless fiberbronchoscopy in Hangzhou First People's Hospital were randomly divided into 2 groups(=14): supraglottic tracheal tube ventilation(group A) and modified laryngeal mask airway(group B). Read More

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December 2018

System justification theory at 25: Evaluating a paradigm shift in psychology and looking towards the future.

Br J Soc Psychol 2018 Dec 7. Epub 2018 Dec 7.

School of Psychology, University of Auckland, New Zealand.

Since first being proposed 25 years ago, system justification theory has become a paradigm-shifting framework for understanding intergroup relations and political psychology. Based on the thesis that people are motivated to defend and bolster the societal status quo, system justification theory helps to explain varied phenomena, including resistance to change, outgroup favouritism, and other instances of false consciousness. This paper summarizes four tenets of the theory including the following: (1) antecedents to system justification, (2) palliative effects of system justification, (3) status-based asymmetries in conflict between justification motives, and (4) societal consequences of system justification. Read More

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December 2018

Unravelling the brain networks driving spike-wave discharges in genetic generalized epilepsy-common patterns and individual differences.

Epilepsia Open 2018 Dec 23;3(4):485-494. Epub 2018 Aug 23.

Department of Neurology and Epileptology Hertie-Institute for Clinical Brain Research University of Tübingen Tübingen Germany.

Objective: Genetic generalized epilepsies (GGEs) are characterized by generalized spike-wave discharges (GSWDs) in electroencephalography (EEG) recordings without underlying structural brain lesions. The origin of the epileptic activity remains unclear, although several studies have reported involvement of thalamus and default mode network (DMN). The aim of the current study was to investigate the networks involved in the generation and temporal evolution of GSWDs to elucidate the origin and propagation of the underlying generalized epileptic activity. Read More

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December 2018

A young woman with fever and loss of consciousness.

BMJ 2018 Dec 6;363:k4363. Epub 2018 Dec 6.

St George's University Hospitals NHS Foundation Trust, London, UK.

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December 2018

Fulminant acute disseminated encephalomyelitis in children.

Brain Dev 2018 Dec 3. Epub 2018 Dec 3.

Department of Pediatrics, St Mary's Hospital, 422 Tsubukuhonmachi, Kurume, Fukuoka 830-8543, Japan; Research Centre for Children and Research Centre for Rett Syndrome, St Mary's Hospital, 422 Tsubukuhonmachi, Kurume, Fukuoka 830-8543, Japan. Electronic address:

Acute disseminated encephalomyelitis (ADEM) is a typically monophasic inflammatory demyelinating disease of the central nervous system with a favorable outcome. However, 2% of ADEM involves acute hemorrhagic leukoencephalitis (AHLE), which is a fulminant and hyperacute variant of ADEM with a poor outcome and high mortality. There are limited case reports of fulminant ADEM including AHLE in children. Read More

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December 2018

Impaired Consciousness in the Emergency Department.

Eur Neurol 2018 Dec 12;80(3-4):179-186. Epub 2018 Dec 12.

Department of Neurology, Hospital of the Ludwig-Maximilians-University (LMU), Munich,

Background: The approach to unconscious patients in the emergency department (ED) is difficult, often depends on local resources and interests, and workup strategies often lack standardization. One reason for this is that data on causes, management, and outcome of patients who present to the ED with sudden onset unconsciousness of unknown cause is limited.

Objectives: This study was performed to analyze the causes of acute impaired consciousness in patients in an interdisciplinary ED. Read More

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December 2018
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The face-to-face encounter in indigenous health care: a perspective in Lévinas.

Rev Bras Enferm 2018 ;71(suppl 6):2848-2853

Universidade Federal Fluminense, Aurora Nursing School of Affonso Costa. Niterói, Rio de Janeiro, Brazil.

Objective: To reflect on the sensitive behaviors of indigenous healthcare professionals based on the philosophy of Emmanuel Lévinas, to ratify completeness, equity, and humanity.

Method: reflective study.

Reflection: Studies have identified inadequacies in meeting the indigenous singularities. Read More

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January 2018

Pathophysiology of Subjective Tinnitus: Triggers and Maintenance.

Front Neurosci 2018 27;12:866. Epub 2018 Nov 27.

Department of Otorhinolaryngology, Head and Neck Surgery, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.

Tinnitus is the conscious perception of a sound without a corresponding external acoustic stimulus, usually described as a perception. One of the major challenges for tinnitus research is to understand the pathophysiological mechanisms triggering and maintaining the symptoms, especially for subjective chronic tinnitus. Our objective was to synthesize the published literature in order to provide a comprehensive update on theoretical and experimental advances and to identify further research and clinical directions. Read More

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November 2018
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Cooperation between Heart Failure Center of Hiroshima University Hospital and a regional medical facility: Option for an end-of-life heart failure patient receiving palliative care.

J Cardiol Cases 2014 Feb 13;9(2):75-79. Epub 2013 Dec 13.

Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, Japan.

A 64-year-old woman with recurrent mitral valve stenosis was hospitalized 30 years after open commissurotomy. Severe right cerebral embolism occurred at age 58, with left hemiparesis. She was debilitated with cardiac cachexia. Read More

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February 2014

Vasospastic angina resulting in sudden cardiac arrest, initially misdiagnosed as a psychiatric disorder.

J Cardiol Cases 2015 May 18;11(5):150-154. Epub 2015 Mar 18.

Cardiovascular Center, International University of Health and Welfare, Mita Hospital, Tokyo, Japan.

A 51-year-old-woman with a history of ablation therapy due to Wolff-Parkinson-White syndrome had been suffering from ambiguous chest pain, prompting investigation by several cardiologists. After being dissatisfied with a psychiatric disorder diagnosis, she was admitted to our hospital for further investigation. She lost her consciousness due to a sudden cardiac arrest shortly after admission. Read More

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Prolonged hyponatremia due to hypopituitarism in a patient with non-ST-elevation myocardial infarction.

J Cardiol Cases 2014 Dec 30;10(6):226-230. Epub 2014 Aug 30.

Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.

A 58-year-old man was admitted for non-ST-elevation myocardial infarction. A medicated stent was used for severe coronary artery stenosis. However, consciousness level progressively deteriorated after angioplasty. Read More

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December 2014

Successful implanted pacemaker for an extreme inhibitory reflex syncope evoked by post herpetic trigeminal neuralgia.

J Cardiol Cases 2013 Jun 25;7(6):e173-e175. Epub 2013 Mar 25.

Department of Cardiology, Veterans Affairs Medical Center, Dayton, OH, USA.

Syncope is defined as a transient loss of consciousness due to cerebral hypoperfusion characterized by rapid onset, short duration, and spontaneous complete recovery. Numerous causes of syncope have been described. Vasovagal syncope is the most common with a number of precipitants. Read More

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A case of idiopathic ventricular fibrillation in which implanted loop recorder was useful in application decision for implantation of implantable cardioverter-defibrillator.

J Cardiol Cases 2012 Aug 20;6(2):e59-e63. Epub 2012 Jun 20.

Division of Cardiology, Department of Internal Medicine, Uwajima City Hospital, Goten-machi 1-1, Uwajima, Ehime 798-8510, Japan.

Establishing a symptom-rhythm correlation in patients with unexplained syncope is complicated because of its sporadic, infrequent, and unpredictable nature. Recently, an implantable loop recorder (ILR) has become available to evaluate undiagnosed recurrent arrhythmic episodes particularly in unexplained syncopes, and its usefulness has been reported in patients with recurrent syncopes that remain unexplained after conventional work-up. A 65-year-old man was referred to our hospital for loss of consciousness with nocturnal paroxysmal seizures. Read More

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Recurrence of ventricular fibrillation in a patient with non-type 1 Brugada electrocardiographic morphology.

J Cardiol Cases 2012 Jul 17;6(1):e17-e19. Epub 2012 May 17.

First Department of Internal Medicine, Niigata University School of Medicine, Niigata, Japan.

A healthy 25-year-old man suffered from loss of consciousness due to ventricular fibrillation (VF). Emergency services required multiple cardioversion to restore sinus rhythm. Repeated electrocardiographic (ECG) recordings after admission showed non-type 1 Brugada ST-segment elevation in V1 and V2. Read More

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Acquired long QT syndrome and ventricular tachycardia in a patient on flecainide therapy.

J Cardiol Cases 2011 Jun 29;3(3):e137-e142. Epub 2011 Mar 29.

Division of Cardiology, Department of Internal Medicine, Yeungnam University Hospital, 317-1 Daemyoung Dong, Nam-Gu, Daegu 705-717, South Korea.

This case report describes a 54-year-old man presenting with loss of consciousness due to acquired long QT syndrome shortly after flecainide therapy. The patient had no common risk factors for acquired long QT syndrome. Prior to onset of ventricular tachycardia, bradyarrhythmia and short-long-short sequence were observed with a prolonged QT interval of 710 ms. Read More

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Explaining consumers' intentions towards purchasing green food in Qingdao, China: The amendment and extension of the theory of planned behavior.

Appetite 2018 Dec 8. Epub 2018 Dec 8.

Department of Organic Food Quality and Food Culture, Faculty of Organic Agricultural Sciences, University of Kassel, Nordbahnhofstrasse 1A, 37213, Witzenhausen, Germany.

This study aims to investigate consumers' green food purchase intentions using a survey conducted in Qingdao, Shandong Province, China. Based on the Theory of Planned Behavior (TPB), it models the influences of Chinese culture and consumer characteristics towards purchasing green food products. According to TPB, the behavioral intention is determined by attitude, subjective norms and perceived behavioral control, whereas subjective norms vary according to differences in cultural systems. Read More

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December 2018

Understanding vasovagal syncope akin to the philosopher's stone?

J Cardiovasc Electrophysiol 2018 Dec 11. Epub 2018 Dec 11.

National Heart & Lung Institute, Imperial College, Hammersmith Hospital, London, UK.

Vasovagal syncope (VVS), the most common form of transient loss of consciousness, still awaits a complete understanding of its role in human physiology. This article is protected by copyright. All rights reserved. Read More

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December 2018
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Spontaneous future cognitions: an integrative review.

Authors:
Dorthe Berntsen

Psychol Res 2018 Dec 10. Epub 2018 Dec 10.

Department of Psychology and Behavioural Sciences, Center on Autobiographical Memory Research, Aarhus University, Bartholins Allé 11, 8000, Aarhus C, Denmark.

Spontaneous future cognitions refer to mental representations about the future that enter consciousness with no immediately preceding attempt of bringing them to mind. They are studied under different terms in several areas of psychology, but with little interdisciplinary exchange of findings and theoretical developments. Different conceptions of spontaneous future cognition derive from separate literatures and are rarely considered together, leaving their potential conceptual overlaps as well as their unique features unclarified. Read More

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December 2018

Adolescent Paranoia: Prevalence, Structure, and Causal Mechanisms.

Schizophr Bull 2018 Dec 10. Epub 2018 Dec 10.

Department of Psychiatry, University of Oxford, Oxford, UK.

Background: Adolescence can be a challenging time, characterized by self-consciousness, heightened regard for peer acceptance, and fear of rejection. Interpersonal concerns are amplified by unpredictable social interactions, both online and offline. This developmental and social context is potentially conducive to the emergence of paranoia. Read More

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December 2018

Parallel and functionally segregated processing of task phase and conscious content in the prefrontal cortex.

Commun Biol 2018 5;1:215. Epub 2018 Dec 5.

1Department of Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, 72076 Tübingen, Germany.

The role of lateral prefrontal cortex (LPFC) in mediating conscious perception has been recently questioned due to potential confounds resulting from the parallel operation of task related processes. We have previously demonstrated encoding of contents of visual consciousness in LPFC neurons during a no-report task involving perceptual suppression. Here, we report a separate LPFC population that exhibits task-phase related activity during the same task. Read More

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December 2018

Coronary Air Embolism During Coronary Angiography : A Systematic Review.

Scifed J Cardiol 2018 3;2. Epub 2018 Aug 3.

Department of Internal Medicine, State University of New York, Downstate Medical Center, Brooklyn, New York, U.S.A.

Coronary air embolism (CARE) is a rare complication during transluminal coronary angiography or angioplasty and is almost always iatrogenic. CARE can cause significant morbidity and mortality as shown in animal studies. CARE is known to cause acute chest pain, hypotension, bradycardia, ST-segment elevation myocardial infarction (STEMI), and death. Read More

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August 2018
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Delayed neurologic sequelae of carbon monoxide intoxication.

Turk J Emerg Med 2018 Dec 21;18(4):167-169. Epub 2018 Apr 21.

Ankara Numune Education and Research Hospital, Department of Radiology, Ankara, Turkey.

Altered consciousness and accompanying neurological symptoms are both complex and challenging cases for emergency physicians. These are not specific and may be a sign of a variety of medical conditions including stroke and delayed neurological sequelae (DNS) is a recurrent transient neuropsychiatric consequence of CO intoxication. DNS produces a spectrum of varying symptoms and the diagnosis is primarily made on the basis of clinical features and radiological findings from CT and conventional MRI. Read More

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December 2018

Comparison of the Effect of Bupivacaine in Combination with Dexmedetomidine with Bupivacaine Plus Placebo on Neonatal Apgar Score, Bispectral Index, and Sedation Level of Parturient Women.

Anesth Pain Med 2018 Oct 24;8(5):e81947. Epub 2018 Oct 24.

Department of Anesthesiology and Critical Care, Shohada-e-Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Objectives: In this study, we aimed to compare the effects of bupivacaine alone and in combination with dexmedetomidine on postoperative analgesia, neonatal Apgar score, and bispectral index (BIS), which has been shown to correlate with increased sedation and loss of consciousness in women undergoing cesarean section under spinal anesthesia.

Methods: A total of 152 term parturient women scheduled to have elective cesarean section with American Society of Anesthesiologist (ASA) physical status I or II were allocated randomly into two groups to receive either bupivacaine plus placebo (BV group) or bupivacaine plus dexmedetomidine (BVD group). BIS, sedation scale scores, Apgar scores, and hemodynamic characteristics were recorded and statistically compared between the groups. Read More

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October 2018

Autoimmune hypoglycaemia caused by alpha-lipoic acid: a rare condition in Caucasian patients.

Endocrinol Diabetes Metab Case Rep 2018 Dec 11;2018. Epub 2018 Dec 11.

ENETS Center of Excellence, Department of Medicine, University of Verona, Verona, Italy.

Insulin autoimmune syndrome (IAS), a rare cause of autoimmune hyperinsulinaemic hypoglycaemia, is relatively well known in Japan. The incidence in Caucasians is less than one-fifth of that reported in Japanese people, but it is becoming increasingly recognised worldwide in non-Asians as well. Drugs containing sulphydryl groups are known to be associated with the disease in genetically predisposed individuals. Read More

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December 2018
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The Embodied Self, the Pattern Theory of Self, and the Predictive Mind.

Authors:
Albert Newen

Front Psychol 2018 23;9:2270. Epub 2018 Nov 23.

Institut für Philosophie II, Ruhr-Universität Bochum, Bochum, Germany.

Do we have to presuppose a self to account for human self-consciousness? If so, how should we characterize the self? These questions are discussed in the context of two alternatives, i.e., the no-self position held by Metzinger (2003, 2009) and the claim that the only self we have to presuppose is a narrative self (Dennett, 1992; Schechtman, 2007; Hardcastle, 2008) which is primarily an abstract entity. Read More

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November 2018

The disturbance in dynamic property in the reconstructed state space during nitrous oxide administration.

Neuroreport 2018 Dec 7. Epub 2018 Dec 7.

Department of Pediatric Dentistry, School of Dentistry, Dental Research Institute, Seoul National University, Seoul, Republic of Korea.

Integration of neural information could be considered a crucial element in maintaining consciousness. Although consciousness is usually maintained during sedation, strictly speaking, the sedative state is different from consciousness. Nitrous oxide (N2O) has been used widely to sedate patients for dental procedures. Read More

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December 2018

[Thrombotic microangiopathy developing subsequent to tocilizumab therapy in a patient with TAFRO syndrome].

Rinsho Ketsueki 2018 ;59(11):2432-2437

Department of Pathology, Hakodate Municipal Hospital.

We report a case of a 60-year-old male who presented with fever and anasarca as well as hepatosplenomegaly, general lymphadenopathy, and disseminated intravascular coagulation (DIC), and was, therefore, admitted to our hospital. In addition, the patient suffered from respiratory failure and renal dysfunction and had pleural effusion and ascites. The pathological diagnosis from lymph node biopsy suggested multicentric Castleman's disease of the plasma cell type; however, the presence of high IL-6 levels, myelofibrosis, thrombocytopenia, anasarca, renal dysfunction, and hepatosplenomegaly led to a definitive diagnosis of TAFRO syndrome. Read More

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January 2018

De novo absence status epilepticus in three paediatric patients: a new idiopathic epilepsy syndrome?

Epileptic Disord 2018 Dec 10. Epub 2018 Dec 10.

Hospital de Pediatría "La madre y el Niño", Formosa, Argentina.

Absence status epilepticus (ASE) is a prolonged generalized absence seizure that usually lasts for hours and can even last for days. The main symptom is the altered content of consciousness while the patient may be alert and partly responsive. We describe the electroclinical features, treatment, and evolution of three paediatric patients with de novo ASE with an excellent response to valproic acid (VPA). Read More

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December 2018

Emotional Reaction to viewing one's own epileptic seizure.

Seizure 2018 Nov 24;64:34-40. Epub 2018 Nov 24.

Epilepsy Center, Freiburg University Medical Center, Germany.

Purpose: If consciousness or memory are impaired during an epileptic seizure, the patient may not experience or know how his/her own seizure looks like. It is disputed, whether being confronted with own seizures may lead to emotional stress or empower patients and decrease negative psychosocial consequences. We assessed patients' reactions to watching a video of their own seizure on measures of anxiety, depression and ten emotions. Read More

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November 2018

Relationship of critical dynamics, functional connectivity, and states of consciousness in large-scale human brain networks.

Neuroimage 2018 Dec 6. Epub 2018 Dec 6.

Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI, United States; Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, MI, United States. Electronic address:

Recent modeling and empirical studies support the hypothesis that large-scale brain networks function near a critical state. Similar functional connectivity patterns derived from resting state empirical data and brain network models at criticality provide further support. However, despite the strong implication of a relationship, there has been no principled explanation of how criticality shapes the characteristic functional connectivity in large-scale brain networks. Read More

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December 2018

White dreams are made of colours: What studying contentless dreams can teach about the neural basis of dreaming and conscious experiences.

Sleep Med Rev 2018 Nov 14;43:84-91. Epub 2018 Nov 14.

Cognitive Neuroscience Research Unit, CFIN, Aarhus University, Denmark.

Reports of white dreams, the feeling of having had a dream experience without being able to specify this experience any further, make up almost one third of all dream reports, yet this phenomenon-until very recently-had not yet been in the focus of targeted investigations. White dreams are typically interpreted as forgotten dreams, and are sidelined as not being particularly informative with regard to the nature of dreaming. In this review article, we propose a paradigm shift with respect to the status of white dreams arguing that focusing on this phenomenon can reveal fundamental insights about the neural processes that occur in the dreaming brain. Read More

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November 2018

Severe Hypoglycemia Due to Cryptic Insulin Use in a Bodybuilder.

J Emerg Med 2018 Dec 6. Epub 2018 Dec 6.

Assistance Publique-Hôpitaux de Paris, Hôpitaux Universitaires Henri Mondor, Service d'Accueil des Urgences, Créteil, France; Université Paris-Est Créteil, Institut National de la Santé et de la Recherche Médicale U955, Créteil, France.

Background: Bodybuilding is a demanding sport, which requires high-volume, high-resistance weight training and augmented nutritional intake, toward an increase of overall body muscle mass accompanied by an overall decrease of body fat percentage and mass. Among bodybuilders, the use of various legal and illegal supplements is common. These supplements may be naturally occurring or man-made. Read More

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December 2018