23,259 results match your criteria Conjunctivitis Neonatal


[Sweet's syndrome induced by pegfilgrastim during a myelodysplastic syndrome AREB2: A case report].

Rev Med Interne 2018 Dec 11. Epub 2018 Dec 11.

Service d'hématologie-oncologie, CHU Brugmann, 4, place Arthur Van Gehuchten, 1020 Bruxelles, Belgique.

Introduction: Sweet's syndrome is an acute neutrophilic dermatosis characterized by abrupt onset of skin lesions accompanied by fever, arthralgia, leukocytosis and diffuse neutrophilic infiltration of the dermis, as well as an excellent response to corticosteroid therapy.

Case Report: A 46-year-old patient with myelodysplastic syndrome was admitted for chemotherapy. On the eighth day of chemotherapy, he received a single dose of pegfilgrastim. Read More

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December 2018
2 Reads

[Observation on pollinosis with vegetable food allergy].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(23):1779-1783

Department of Allergy, Beijing Shijitan Hospital, Affiliated to Capital Medical University, Beijing, 100038, China.

To investigate the incidence of plant food allergy in patients with pollinosis and the effect of food allergens on the clinical symptoms of pollinosis patients. A total of 40 patients with pollinosis and food allergy attended to the allergy Department of Duolun People's Hospital of Inner Mongolia were accepted skin prick test of inhaled allergens while the rhino conjunctivitis quality of life questionnaire(RQLQ) were also completed. The patients were divided into A and B groups randomly. Read More

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December 2018
2 Reads

[The sensitization feature of artemisia allergy and the diagnosis value of skin prick test].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(24):1860-1864

Department of Allergy, Beijing Shijitan Hospital, Capital Medical University, Beijing, 100038, China.

The purpose of this study was to explore the sensitization feature of artemisia allergy and to assess the diagnostic value of skin prick test(SPT) compared with specific IgE(sIgE) test. One hundred and fifty-one patients with typical rhino-conjunctivitis symptoms during pollen season were enrolled and general information was recorded in this study. All subjects received SPT and sIgE test of artemisia allergen. Read More

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December 2018
1 Read

A Case of Acute Granulomatous Conjunctivitis Caused by Cat-transmitted Sporothrix schenckii.

Cureus 2018 Oct 8;10(10):e3428. Epub 2018 Oct 8.

Ophthalmology, School of Medical Sciences/Universiti Sains Malaysia, Kota Bharu, MYS.

In human, sporotrichosis infection commonly manifests as skin lesions through direct inoculation. It is rarely associated with ocular manifestation via a zoonotic transmission. We describe a young lady who presented with acute left eye granulomatous conjunctivitis who had a history of exposure to her sick cat diagnosed with sporotrichosis infection. Read More

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October 2018

The proportion, conditions, and predictors of emergency department visits that can be potentially managed by pharmacists with expanded scope of practice.

Res Social Adm Pharm 2018 Dec 7. Epub 2018 Dec 7.

School of Pharmacy, University of Waterloo, 10 Victoria St S A, Kitchener, N2G 1C5, ON, Canada; Ontario Pharmacy Evidence Network (OPEN), School of Pharmacy, University of Waterloo, 10 Victoria St S A, Kitchener, N2G 1C5, ON, Canada.

Background: Pharmacists have been shown to be beneficial for inclusion in emergency department (ED) services; however, little has been done to assess these benefits with pharmacists having even wider scopes of practice, including limited prescribing authority.

Objectives: The aims of this study were to determine the proportion of ED visits that can potentially be managed by pharmacists, the most prevalent conditions within these cases, and the factors associated with patients presenting with such cases to the ED.

Methods: This was a retrospective quantitative cohort study using administrative databases from 2010 to 2017. Read More

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December 2018

A case report on complete cure of recurrent primary canaliculitis by 4-snip punctoplasty and canalicular curettage.

Authors:
Min Ho Kim Ho Ra

Medicine (Baltimore) 2018 Dec;97(49):e13508

Department of Ophthalmology and Visual Science, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

Rationale: For the treatment of primary canaliculitis, 1,2,3-snip punctoplasty and canalicular curettage are commonly used; however, a recurrence rate of 6.6% to 22% has been reported. Herein, we describe a case of recurrent primary canaliculitis that was completely cured by 4-snip punctoplasty and canalicular curettage. Read More

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December 2018

NMR resonance assignments of the pathogenesis-related peach allergen Pru p 1.0101.

Biomol NMR Assign 2018 Dec 12. Epub 2018 Dec 12.

Institute of Organic Chemistry and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innrain 80/82, 6020, Innsbruck, Austria.

In Europe, Northern America, and China a large number of individuals are suffering from peach (Prunus persica) allergy caused by the protein Pru p 1. Immunologic reactions against this 17.5 kDa protein result from initial sensitization to the birch (Betula verrucosa) pollen allergen Bet v 1 and subsequent immunologic cross-reactivity of Bet v 1 specific antibodies. Read More

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December 2018

Evolution of symptoms and quality of life during Zika virus infection: A 1-year prospective cohort study.

J Clin Virol 2018 Dec 26;109:57-62. Epub 2018 Sep 26.

French Armed Forces Health Service in French Guiana, Cayenne, French Guiana; Unité de Parasitologie et Entomologie, Département des Maladies Infectieuses, Institut de Recherche Biomédicale des Armées, Marseille, France; Aix Marseille Université, IRD, AP-HM, SSA, UMR Vecteurs - Infections Tropicales et Méditerranéennes (VITROME), IHU - Méditerranée Infection, Marseille, France.

Background: Although the complications of Zika virus infection have been well described, the clinical pattern has not been reported in enough detail to differentiate this infection from those with other arboviroses, and no longitudinal study has yet been published on the persistence of symptoms and quality of life.

Objectives: were to describe bio-clinical pattern and quality of life during ZIKV infection, and their evolution.

Study Design: We present a 1-year clinical follow-up of 49 people infected with Zika virus in French Guiana, for whom the diagnosis was confirmed by RT-PCR in serum or urine. Read More

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December 2018

The Role of Pneumococcal Virulence Factors in Ocular Infectious Diseases.

Interdiscip Perspect Infect Dis 2018 13;2018:2525173. Epub 2018 Nov 13.

Department of Microbiology and Immunology, University of Mississippi Medical Center, Jackson, MS 39216, USA.

is a gram-positive, facultatively anaerobic pathogen that can cause severe infections such as pneumonia, meningitis, septicemia, and middle ear infections. It is also one of the top pathogens contributing to bacterial keratitis and conjunctivitis. Though two pneumococcal vaccines exist for the prevention of nonocular diseases, they do little to fully prevent ocular infections. Read More

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November 2018
1 Read

Long-term efficacy and dose-finding trial of Japanese cedar pollen SLIT tablet.

J Allergy Clin Immunol Pract 2018 Dec 8. Epub 2018 Dec 8.

Department of Otolaryngology, Head and Neck Surgery, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan.

Background: Japanese cedar (JC) pollinosis is a common allergic rhinitis in Japan. The JC pollen SLIT tablet was developed using the highest concentration of JC pollen extract.

Objective: This was a randomized, double-blind, placebo-controlled phase II/III trial to investigate the optimal dose of the JC pollen SLIT tablet and examine long-term efficacy and safety for 3 years with the selected dose, and 2-year follow-up. Read More

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December 2018
1 Read

Outbreak of Epidemic Keratoconjunctivitis Caused by Human Adenovirus Type D53 in an Eye Care Clinic - Los Angeles County, 2017.

MMWR Morb Mortal Wkly Rep 2018 Dec 7;67(48):1347-1349. Epub 2018 Dec 7.

On June 22, 2017, the Los Angeles County Department of Public Health (LAC DPH) was notified of seven patients who were seen at an eye care clinic on June 8, 2017, and later developed symptoms of epidemic keratoconjunctivitis (EKC). EKC is a contagious, severe form of viral conjunctivitis that can cause pain and blurred vision for up to 4 weeks (1). LAC DPH conducted an investigation, which identified 17 patients with EKC, including 15 who had visited the optometry clinic and two who were household contacts of clinic patients. Read More

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December 2018
6 Reads

Spatiotemporal clustering of cases of Kawasaki disease and associated coronary artery aneurysms in Canada.

Sci Rep 2018 Dec 5;8(1):17682. Epub 2018 Dec 5.

Ted Rogers Centre for Heart Research, Peter Munk Cardiac Centre, University Health Network, University of Toronto, Ontario, Canada.

Detailed epidemiologic examination of the distribution of Kawasaki disease (KD) cases could help elucidate the etiology and pathogenesis of this puzzling condition. Location of residence at KD admission was obtained for patients diagnosed in Canada (excluding Quebec) between March 2004 and March 2015. We identified 4,839 patients, 164 of whom (3. Read More

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December 2018
1 Read

Probable Roles of Coagulation Cascade and Fibrinolysis System in the Development of Allergic Rhinitis.

Am J Rhinol Allergy 2018 Dec 6:1945892418816015. Epub 2018 Dec 6.

3 Department of Otorhinolaryngology, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Republic of Korea.

Background: Dysregulation of the coagulation cascade and fibrinolysis system may play an etiologic role in many diseases. Allergic diseases such as bronchial asthma, atopic dermatitis, and conjunctivitis are also associated with fibrin accumulation caused by a change in hemostasis. However, only a few studies have dealt with the relationship between allergic rhinitis (AR) and the coagulation system. Read More

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December 2018
1 Read

Adult conjunctivitis secondary to dual infection with and - A case report.

Am J Ophthalmol Case Rep 2019 Mar 14;13:6-8. Epub 2018 Nov 14.

Manchester Royal Eye Hospital, Oxford Road, Manchester, M13 9WL, UK.

Purpose: Although and are the commonest sexually transmitted infections in England, reports of ocular co-infection in the literature are limited. We report such a case which responded well to treatment, and discuss the literature and evidence currently available with regards to management of these cases.

Observations: The patient is a 48-year-old bisexual gentleman who presented to the eye clinic of a UK hospital with redness, discharge and blurred vision in his left eye for one week. Read More

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March 2019
1 Read

IL-27 Signaling Deficiency Develops Th17-enhanced Th2-dominant Inflammation in Murine Allergic Conjunctivitis Model.

Allergy 2018 Dec 4. Epub 2018 Dec 4.

Ocular Surface Center, Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, Texas, USA.

Background: While most studies focus on pro-allergic cytokines, the protective role of immunosuppressive cytokines in allergic inflammation is not well elucidated. This study was to explore a novel anti-inflammatory role and cellular/molecular mechanism of IL-27 in allergic inflammation.

Methods: A murine model of experimental allergic conjunctivitis (EAC) was induced in BALB/c, C57BL/6 or IL-27Rα deficient (WSX-1 ) mice by short ragweed pollen, with untreated or PBS-treated mice as controls. Read More

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December 2018
1 Read

Diagnosis of a case of ligneous gingivitis in a patient with moderate plasminogen deficiency.

J Stomatol Oral Maxillofac Surg 2018 Dec 1. Epub 2018 Dec 1.

Service d'Odontologie du CHU, 549 avenue du Pr JL Viala, 34295 Montpellier cedex 5, France. Electronic address:

Plasminogen deficiency is a rare congenital condition that leads to pseudomembraneous lesions, such as ligneous conjunctivitis and ligneous gingivitis. Because of its rarity, ligneous gingivitis is not a pathology one may easily suspect from its clinical symptoms. We report the case of a 35-year-old Caucasian woman who experienced gum masses with white spots, but no pain. Read More

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December 2018
3 Reads

Cross-linked hyaluronic acid gel occlusive device for the treatment of dry eye syndrome.

Authors:
John P Fezza

Clin Ophthalmol 2018 8;12:2277-2283. Epub 2018 Nov 8.

Center for Sight, Sarasota, FL, USA,

Purpose: A new cross-linked hyaluronic acid (xlHA) gel occlusive device was assessed for safety and efficacy in the treatment of dry eyes.

Methods: This was an institutional review board-approved, single-site, open-label, prospective study to assess the efficacy and safety of placing the xlHA gel in the lower canaliculus. Seventy-four participants aged 25-95 years with dry eyes, who failed treatment with artificial tears, were included. Read More

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November 2018
5 Reads

Neonatal conjunctivitis in the New Zealand Midland region.

N Z Med J 2018 Nov 30;131(1486):9-17. Epub 2018 Nov 30.

Ophthalmologist, Clinical Senior Lecturer, Ophthalmology Department, Department of Medicine, Hauora Tairawhiti, University of Otago, Gisborne.

Aims: To assess the incidence of chlamydial and gonorrhoeal neonatal conjunctivitis (CON and GON), across six district health boards in the greater Midland region of New Zealand.

Methods: All positive nucleic acid amplification test (NAAT) eye swabs for Chlamydia trachomatis and NAAT and bacterial eye swabs for Neisseria gonorrhoeae in infants under one year of age were retrieved from three laboratories from 2013-2016. Incidence density rates were calculated using births information from Statistics New Zealand. Read More

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November 2018
6 Reads

Infantile Acute Conjunctivitis Induced by β-Lactamase-Positive Amoxicillin-Clavulanate-Resistant Strain of Haemophilus influenzae: A Report of Three Cases.

Eye Contact Lens 2018 Nov 22. Epub 2018 Nov 22.

Division of Ophthalmology, Department of Visual Sciences, Nihon University School of Medicine, Tokyo, Japan.

This study is a retrospectively recruited case series. We report three infants with acute conjunctivitis induced by β-lactamase-positive, ampicillin/clavulanic acid-resistant strains of Haemophilus influenzae (BLPACR). Patients with BLPACR-positive cultures were recruited from among 5,107 patients with inflammatory diseases of the ocular surface who underwent examinations, including bacterial culturing of conjunctival sac or corneal scrapings, between 2000 and 2015. Read More

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November 2018
2 Reads

Epicutaneous immunotherapy in rhino-conjunctivitis and food allergies: a review of the literature.

J Transl Med 2018 Nov 27;16(1):329. Epub 2018 Nov 27.

Pediatric Clinic, Department of Surgical and Biomedical Sciences, Università degli Studi di Perugia, Piazza Menghini 1, 06129, Perugia, Italy.

Background: Epicutaneous immunotherapy (EPIT) is a new way of allergen administration that has a high rate of adherence and safety. The aim of this manuscript is to review clinical trials on EPIT for respiratory and food allergies published in the last 10 years, taking into account how different variables (i.e. Read More

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November 2018
1 Read

Sleep Disorders are a Prevalent and Serious Comorbidity in Dry Eye.

Invest Ophthalmol Vis Sci 2018 Nov;59(14):DES143-DES150

Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.

Purpose: Sleep is an essential life habit and closely associated with lifespan, diabetes, hypertension, and mental health. Sleep disorders are a prominent, but overlooked problem in patients with dry eye disease (DED), characterized by a poor sleep index, short sleep duration, long sleep latency, and poor subjective sleep. DED and sleep disorders are more prevalent in women than men. Read More

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November 2018
6 Reads

Inflamed Obstructive Meibomian Gland Dysfunction Causes Ocular Surface Inflammation.

Authors:
Tomo Suzuki

Invest Ophthalmol Vis Sci 2018 Nov;59(14):DES94-DES101

Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.

Meibomian gland dysfunction (MGD) is one of the primary causes of evaporative dry eye. Stagnation of meibum induces an unstable tear film, thus resulting in shortened tear film breakup time and superficial punctate keratopathy (SPK) in the lower cornea and punctate staining of lower bulbar conjunctiva. MGD is sometimes accompanied with inflammation (termed "meibomitis") via the proliferation of bacteria in the meibomian gland and eyelash area. Read More

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November 2018
2 Reads

Challenges in the Polyene- and Azole-Based Pharmacotherapy of Ocular Fungal Infections.

J Ocul Pharmacol Ther 2018 Nov 8. Epub 2018 Nov 8.

1 Department of Pharmaceutics and Drug Delivery, School of Pharmacy, University of Mississippi , Oxford, Mississippi.

Polyenes and azoles constitute 2 major drug classes in the antifungal armamentarium used to treat fungal infections of the eye such as fungal keratitis, endophthalmitis, conjunctivitis, and blepharitis. These classes of drugs have come to occupy an important niche in ophthalmic antifungal therapy due to their broad spectrum of activity against a variety of filamentous and yeast-like fungi. Natamycin suspension (Natacyn), a polyene antifungal drug, is currently the only US FDA-approved formulation for treating ophthalmic fungal infections, whereas the other polyene and azole antifungals such as amphotericin B, fluconazole, itraconazole, ketoconazole, miconazole, voriconazole, and posaconazole are routinely used off-label in the clinical setting. Read More

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November 2018
3 Reads

Conurbation, Urban, and Rural Living as Determinants of Allergies and Infectious Diseases: Royal College of General Practitioners Research and Surveillance Centre Annual Report 2016-2017.

JMIR Public Health Surveill 2018 Nov 26;4(4):e11354. Epub 2018 Nov 26.

Royal College of General Practitioners Clinical Innovation and Research Centre, London, United Kingdom.

Background: Living in a conurbation, urban, or rural environment is an important determinant of health. For example, conurbation and rural living is associated with increased respiratory and allergic conditions, whereas a farm or rural upbringing has been shown to be a protective factor against this.

Objective: The objective of the study was to assess differences in general practice presentations of allergic and infectious disease in those exposed to conurbation or urban living compared with rural environments. Read More

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November 2018
4 Reads

Association between asthma, rhinitis and conjunctivitis multimorbidities with molecular IgE sensitization in adults.

Allergy 2018 Nov 25. Epub 2018 Nov 25.

INSERM, U1168, VIMA: Aging and chronic diseases. Epidemiological and Public health approaches, F-94807, Villejuif, France.

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November 2018
1 Read

Recurrent Kawasaki Disease: A Case Report of Three Separate Episodes at >4-Year Intervals.

Children (Basel) 2018 Nov 21;5(11). Epub 2018 Nov 21.

CHLA Pediatric Cardiology, Children's Hospital Los Angeles, 4650 Sunset Blvd, Los Angeles, CA 90027, USA.

Kawasaki disease (KD) is a self-limited systemic vasculitis, most often occurring in children 1⁻5 years old. It has a 2% recurrence rate and is associated with coronary aneurysms (CA), which can develop within two weeks of onset. A 25% increased risk is noted in patients who are recalcitrant to treatment. Read More

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November 2018
9 Reads

Pharmacokinetics of topically applied tacrolimus dissolved in Marinosolv, a novel aqueous eye drop formulation.

Eur J Pharm Biopharm 2019 Jan 19;134:88-95. Epub 2018 Nov 19.

Clinical Department for Farm Animals and Herd Management, University of Veterinary Medicine Vienna, Veterinärplatz 1, Vienna, Austria.

Corticosteroids and macrolide immunomodulators such as tacrolimus are effective drugs for the topical treatment of inflammatory eye diseases like allergic conjunctivitis or dry eye. However, tacrolimus is practically insoluble in aqueous solutions and is therefore currently formulated as dispersion. This leads to low bioavailability. Read More

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January 2019
4 Reads

Current Breakthroughs in Structure-Based Design of Synthetic and Natural Sourced Inhibitors against Zika Viral Targets.

Curr Top Med Chem 2018 Nov 20. Epub 2018 Nov 20.

Pharmacognosy and Phytotherapy Laboratory, Division of Pharmacognosy, Department of Pharmaceutical Technology, Jadavpur University, Kolkata -700032. India.

Background: Zika is a worldwide pandemic dreadful viral transmission through Aedes mosquito vector. It significantly causes fever, joint pain or rash, and conjunctivitis. Pregnant mothers suffering from Zika viral infection may have fetal abnormalities due to severe neurological problems, characterized by microcephaly along with Guillain-Barré syndrome, issuing ZIKV a major public health concern as declared by the World Health Organization. Read More

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November 2018
2 Reads
3.402 Impact Factor

Neonatal Conjunctivitis Caused by Neisseria cinerea: A Case of Mistaken Identity.

J Pediatric Infect Dis Soc 2018 Nov 21. Epub 2018 Nov 21.

Division of Pediatric Infectious Diseases, Department of Pediatrics, NYU Winthrop Hospital, Mineola, New York.

We report a case of a 3-day-old boy with Neisseria cinerea conjunctivitis, originally misidentified as Neisseria gonorrhoeae conjunctivitis. Neonates are at increased risk for disseminated gonococcal infection, and physicians should be cognizant of N cinerea and its potential to be mistaken for N gonorrhoeae. Read More

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November 2018
3 Reads

Ocular Surface Disease in Birds.

Authors:
Angela Griggs

Vet Clin North Am Exot Anim Pract 2019 Jan;22(1):53-68

North Houston Veterinary Ophthalmology, 1646 Spring Cypress Road, Suite 116, Spring, TX 77388, USA. Electronic address:

Avian ocular disease may be primary or a manifestation of systemic disease. Various infectious and noninfectious diseases have been reported to cause ocular pathology. Thorough physical examination and diagnostic testing are necessary to determine a treatment plan. Read More

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January 2019
1 Read

Ocular Surface Disease in Rodents (Guinea Pigs, Mice, Rats, Chinchillas).

Authors:
Caroline Monk

Vet Clin North Am Exot Anim Pract 2019 Jan;22(1):15-26

Ophthalmology, BluePearl Veterinary Partners, 1071 Howell Mill Road Northwest, Atlanta, GA 30318, USA. Electronic address:

This article discusses the clinical appearance, differential diagnoses, and treatment considerations of corneal disease in the most common domesticated species of rodent: mouse, rat, chinchilla, and guinea pig. Many corneal diseases are related to inbred strains of either research or pet rodents. Diseases are complicated by husbandry and treatment-related challenges in this small, social species. Read More

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January 2019
1 Read

Ocular Surface Disease of Rabbits.

Vet Clin North Am Exot Anim Pract 2019 Jan;22(1):1-14

Comparative Ophthalmology, University of Georgia, 2200 College Station Road, Athens, GA 30202, USA. Electronic address:

Rabbits have become a popular house pet that is encountered with increasing frequency in small animal veterinary practice. The unique anatomy of the rabbit predisposes them to developing surface ocular problems including the development of dacryocystitis, as well as conjunctivitis and keratitis. This article endeavors to give an updated outline of the various conditions affecting the rabbit ocular surface, with emphasis on diagnosis and treatment. Read More

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January 2019
1 Read

Disentangling the heterogeneity of allergic respiratory diseases by latent class analysis reveals novel phenotypes.

Allergy 2018 Nov 17. Epub 2018 Nov 17.

CINTESIS - Center for Health Technology and Services Research, Faculty of Medicine, University of Porto, Porto, Portugal.

Background: Refined phenotyping of allergic diseases may unravel novel phenotypes. Conjunctivitis as an independent disorder has never been approached.

Aim: To identify distinct classes of allergic respiratory diseases using latent class analysis (LCA) and distinguish each class using classification and regression tree (CART) analysis. Read More

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November 2018
6 Reads

αβ integrin inhibitors: a patent review.

Expert Opin Ther Pat 2018 Dec 22;28(12):903-917. Epub 2018 Nov 22.

c Research Division of Clinical Pharmacology , Τhe First Affiliated Hospital of Nanjing Medical University , Nanjing , China.

Introduction: The αβ integrin is heterodimeric cell surface receptors expressed on most leukocytes. Mucosal addressing cell adhesion molecule 1(MAdCAM-1) is an exclusive ligand for αβ integrin. Areas covered: This article will highlight the progress that has been made in the discovery and development of αβ integrin inhibitors, and their use in the treatment of inflammatory bowel diseases, multiple sclerosis, asthma, hepatic disorders, human immunodeficiency virus, allergic conjunctivitis and type 1 diabetes. Read More

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December 2018
6 Reads
4.300 Impact Factor

Ligneous conjunctivitis due to plasminogen deficit: Diagnostic and therapeutic approach. With literature review.

J Fr Ophtalmol 2018 Dec 12;41(10):916-919. Epub 2018 Nov 12.

Nationl institute of ophthalmology, Tunisia University of Tunis El Manar, Faculty of Medicine of Tunis (FMT), Tunisia. Electronic address:

Ligneous conjunctivitis is a rare and poorly understood pathology. Infections and repeated microtraumas are often involved in acute disease flare-ups. This masquerade may lead to misdiagnosis and delayed treatment. Read More

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December 2018
1 Read

Impact of Drinking Water Quality on the Development of Enteroviral Diseases in Korea.

Int J Environ Res Public Health 2018 Nov 14;15(11). Epub 2018 Nov 14.

Department of Social and Preventive Medicine, School of Medicine, Sungkyunkwan University, Suwon 440-746, Korea.

Enterovirus diseases are fecal-orally transmitted, and its transmission may be closely related with the drinking water quality and other environmental factors. This study aimed to assess the association between environmental factors including drinking water quality and the incidence of enteroviral diseases in metropolitan provinces of Korea. Using monthly number of hand-foot-mouth disease (HFMD), aseptic meningitis (AM) and acute hemorrhage conjunctivitis (AHC) cases, generalized linear Poisson model was applied to estimate the effects of environmental factors on the monthly cases. Read More

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November 2018
9 Reads

Topical Antibiotics for Clinical and Microbiological Cure of Bacterial Conjunctivitis.

Acad Emerg Med 2018 Nov 12. Epub 2018 Nov 12.

University of Pittsburgh Medical Center, Department of Emergency Medicine, Pittsburgh, PA.

Acute bacterial conjunctivitis is an infective condition frequently resulting in mucopurulent ocular discharge, bulbar and palpebral injection, and discomfort.. It may be difficult to differentiate between viral and bacterial conjunctivitis on clinical grounds, and swabbing eyes for cultures is not considered clinically practical. Read More

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November 2018
3 Reads

Periostin deletion suppresses late-phase response in mouse experimental allergic conjunctivitis.

Allergol Int 2018 Nov 9. Epub 2018 Nov 9.

Laboratory of Ocular Atopic Diseases, Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan. Electronic address:

Background: To investigate the potential roles of periostin (POSTN), an extracellular matrix preferentially expressed in Th2-skewed conditions in the pathophysiology of allergic conjunctivitis.

Methods: The roles of POSTN in ragweed-induced experimental allergic conjunctivitis (RW-EAC) were evaluated using both POSTN-knockout (KO) and congenic BALB/c wild-type mice. Histological analysis was carried out to enumerate eosinophils/basophils in the conjunctival tissue. Read More

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November 2018
1 Read

Critically appraised topic on adverse food reactions of companion animals (6): prevalence of noncutaneous manifestations of adverse food reactions in dogs and cats.

BMC Vet Res 2018 Nov 12;14(1):341. Epub 2018 Nov 12.

Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, 1060 William Moore Drive, Raleigh, NC, 27607, USA.

Background: Many reports describe the cutaneous signs of adverse food reactions (AFR) in the dog and cat. However, various non-cutaneous clinical signs are less well described. Our objective was to systematically evaluate these non-cutaneous signs of AFR in small animals. Read More

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November 2018
5 Reads

Ophthalmomyiasis externa due to sheep nasal botfly in rural Jamaica.

Trop Doct 2018 Nov 12:49475518809603. Epub 2018 Nov 12.

2 Consultant Ophthalmologist, Ophthalmology Division, Faculty of Medical Sciences, University of the West Indies, Mona, Kingston, Jamaica.

We present the case of a young male patient who presented with pain, redness and foreign body sensation in his left eye. There was no associated decrease in vision. Three live larvae were removed from his left conjunctival sac and sent to the laboratory for identification. Read More

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November 2018
1 Read

Involvement of the annexin A1-Fpr anti-inflammatory system in the ocular allergy.

Eur J Pharmacol 2018 Nov 9;842:298-305. Epub 2018 Nov 9.

UNIFESP - Universidade Federal de São Paulo, Departamento de Morfologia e Genética, São Paulo, SP, Brazil. Electronic address:

Annexin A1 (ANXA1)-formyl peptide receptor (Fpr) system is potent effective mediators in the control of the inflammatory response. In this study, we evaluate the potential involvement of the Fpr family in the protective effect of the mimetic peptide of ANXA1 (ANXA1) using an experimental allergic conjunctivitis (AC) model in mice. Ovalbumin (OVA)/Alum-immunized wild-type (WT) and ANXA1-null (ANXA1) Balb/c mice (days 0 and 7) were challenged by eye drops containing OVA on days 14-16, and two groups received ANXA1 alone or with Fpr antagonist Boc2 intraperitoneally during challenged days. Read More

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November 2018
5 Reads

Air Pollution and Noncommunicable Diseases: A Review by the Forum of International Respiratory Societies' Environmental Comittee. Part 2: Air Pollution and Organ Systems.

Chest 2018 Nov 9. Epub 2018 Nov 9.

School of Earth, Society, and Environment, Department of Atmospheric Sciences, University of Illinois, Urbana, IL.

Although air pollution is well known to be harmful to the lung and airways, it can also damage most other organ systems of the body. It is estimated that about 500,000 lung cancer deaths and 1.6 million COPD deaths can be attributed to air pollution, but air pollution may also account for 19% of all cardiovascular deaths and 21% of all stroke deaths. Read More

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November 2018
6 Reads

Evaluation of content and cost of traditional eye medication in a resource-poor country - Implications for eye care practice and policy.

Niger J Clin Pract 2018 Nov;21(11):1514-1519

Department of Surgery, College of Medicine, University of Nigeria, Nsukka, Enugu State, Nigeria.

Background: Cataract, glaucoma, and conjunctivitis are common causes of ocular morbidity in Nigeria. A major obstacle in reducing the burden of ocular morbidity in rural areas is access to eye care services. Up to 80% of the population in developing countries use traditional medications for their primary healthcare needs because they are accessible, available, and affordable. Read More

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November 2018
5 Reads

Clinical features of cats with aqueous tear deficiency: a retrospective case series of 10 patients (17 eyes).

J Feline Med Surg 2018 Nov 12:1098612X18810867. Epub 2018 Nov 12.

1 Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA, USA.

Objectives: The aim of this study was to describe the clinical findings, diagnostic test results and response to therapy of cats with Schirmer tear test 1 (STT-1) values below the reference interval.

Methods: The medical records of three institutions were searched for cats with ocular surface disease and STT-1 values <9 mm/min, confirmed at two or more separate visits.

Results: Ten cats (17 eyes) were included. Read More

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November 2018
1 Read

A Survey of Current Prophylactic Treatment for Ophthalmia Neonatorum in Croatia and a Review of International Preventive Practices.

Med Sci Monit 2018 Nov 10;24:8042-8047. Epub 2018 Nov 10.

Psychiatric Hospital "Sveti Ivan", Zagreb, Croatia.

BACKGROUND Ophthalmia neonatorum, or neonatal conjunctivitis, is an acute infection that occurs within the first 28 days of life. This aim of this survey was to evaluate the current methods of preventive treatment for ophthalmia neonatorum in maternity hospitals in Croatia. MATERIAL AND METHODS The annual hospital birth rate in Croatia is approximately 40,000. Read More

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November 2018
5 Reads

outbreaks and implications for transmission and control: a systematic review.

Pneumonia (Nathan) 2018 5;10:11. Epub 2018 Nov 5.

1Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina Chapel Hill, Chapel Hill, NC USA.

Background: is capable of causing multiple infectious syndromes and occasionally causes outbreaks. The objective of this review is to update prior outbreak reviews, identify control measures, and comment on transmission.

Methods: We conducted a review of published outbreaks, defined as at least two linked cases of . Read More

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November 2018
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First-reported pediatric cases of American ginseng anaphylaxis and allergy.

Allergy Asthma Clin Immunol 2018 3;14:79. Epub 2018 Nov 3.

1Division of Allergy & Immunology, Department of Pediatrics, University of British Columbia, British Columbia Children's Hospital, 4480 Oak St., Vancouver, BC V6H3N1 Canada.

Background: Ginseng is a perennial herb used in traditional Chinese medicine, which has become increasingly popular world-wide due to its proposed medicinal effects. There are two major species of ginseng, (Korean or Asian ginseng), and (American ginseng). Although cases of allergy due to Korean ginseng have been reported in adults, there are no reported cases of allergy to American ginseng, and no reported cases of ginseng allergy in pediatric patients. Read More

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November 2018
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Torticollis as Presentation for Atypical Kawasaki Disease Complicated by Giant Coronary Artery Aneurysms.

Case Rep Pediatr 2018 8;2018:4236264. Epub 2018 Oct 8.

Department of Pediatrics, Memorial University, 300 Prince Phillip Drive, St. John's, NL, Canada A1B 3V6.

Kawasaki disease (KD) is an acute systemic vasculitis of childhood. The diagnosis can be made in a patient who presents with a prolonged high fever and meeting at least four of five criteria including polymorphous rash, mucosal changes, extremity changes (including swelling and/or palmar and plantar erythema), bilateral nonsuppurative conjunctivitis, and unilateral cervical lymphadenopathy. Atypical KD refers to patients who have not met the full criteria and in whom atypical features may be present. Read More

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October 2018
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Zika, afebrile disease?

Rev Med Inst Mex Seguro Soc 2018 10 25;56(3):305-308. Epub 2018 Oct 25.

Instituto Mexicano del Seguro Social, Hospital General de Zona No. 71, Departamento de Medicina Interna. Veracruz, Veracruz, México

In this paper, we emphasize on a probable atypical case of Zika, which is essentially a febrile illness; however, nowadays it has been noticed that fever is not always present in Zika cases, and the incidence of this clinical sign varies in several series; besides, we point out that symptoms such as nonpurulent conjunctivitis or rash could be reliable criteria in the absence of fever for the probable diagnosis of Zika, which invariably requires serological confirmation, even though the latter is not always available. Read More

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October 2018
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