2,063 results match your criteria Conjunctivitis Neonatal

Quality of Informed Consent Practices around the Time of Childbirth: A Cross-Sectional Study in Italy.

Int J Environ Res Public Health 2022 Jun 10;19(12). Epub 2022 Jun 10.

Institute for Maternal and Child Health, IRCCS "Burlo Garofolo", WHO Collaborating Centre for Maternal and Child Health, Via dell'Istria 65/1, 34137 Trieste, Italy.

Background: Few studies have explored consent request practices during childbirth.

Objective: We explored consent request practices during childbirth in a referral hospital and research centre in Italy, capturing both women and health workers' perspectives.

Methods: Data were collected using self-administrated questionnaires between December 2016 and September 2018. Read More

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Prevalence of active trachoma and its associated factors among 1-9 years of age children from model and non-model kebeles in Dangila district, northwest Ethiopia.

PLoS One 2022 15;17(6):e0268441. Epub 2022 Jun 15.

Department of Public Health, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.

Background: Trachoma is the leading infectious disease that leads to blindness worldwide, especially in developing countries. Though Ethiopia had targeted a trachoma elimination program by 2020, the problem worsens, particularly in the Amhara Region. Even though sustained intervention measures are undertaken across the region, it is unclear why trachoma is still a significant public health problem. Read More

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conjunctivitis in the pre-pubertal child.

Arch Dis Child Educ Pract Ed 2022 Jun 14. Epub 2022 Jun 14.

The Rowan, Sexual Assault Referral Centre, Northern Health and Social Care Trust, Antrim, UK.

Much is reported in the literature about the transmission and presentation of conjunctival infection in the neonate; however, there is a paucity of information available on infection in the older pre-pubertal child (>3 years of age). We present the case of a 7-year-old girl, referred for assessment at the sexual assault referral centre following the diagnosis of unilateral conjunctivitis. This child underwent a rigorous multiagency child protection process, with input from medical professionals, social services and the police to investigate the possibility of child sexual abuse (CSA). Read More

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[Ocular abnormalities of children born prematurely at the Yaoundé Gynaeco-Obstetrics And Pediatric Hospital].

J Fr Ophtalmol 2022 Jun 18;45(6):633-639. Epub 2022 May 18.

Faculté de médecine et des sciences biomédicales, université de Yaoundé I, Yaoundé, Cameroun; Hôpital gynéco-obstétrique et pédiatrique de Yaoundé, Yaoundé, Cameroun.

Purpose: To identify ocular abnormalities in premature children in order to treat reversible visual disorders and help prevent low vision and blindness in this population at risk.

Methodology: This was a cross-sectional, analytical study carried out from November 1, 2018 to July 31, 2019 at the Yaoundé Gyneco-Obstetric And Pediatric Hospital, including premature children, aged 3 to 15 years. The variables studied were age, sex, prenatal, birth and past ophthalmological history, visual acuity, oculomotor examination and fundus examination. Read More

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A Newborn with a Purulent Ocular Discharge.

Pediatr Ann 2022 May 1;51(5):e206-e208. Epub 2022 May 1.

An 11-day-old girl, who was diagnosed with Neisseria gonorrhoeae ophthalmia neonatorum, presents with a purulent ocular discharge. Although rare in regions with high implementation rates of ocular prophylaxis, ophthalmia neonatorum remains an important diagnostic consideration, especially in developing countries and areas of low socioeconomic status. In this article, we review the evolving epidemiology, diagnostic considerations, prevention, and treatment of ophthalmia neonatorum. Read More

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Seasonal variation in water use for hygiene in Oromia, Ethiopia, and its implications for trachoma control: An intensive observational study.

PLoS Negl Trop Dis 2022 05 13;16(5):e0010424. Epub 2022 May 13.

Clinical Research Department, London School of Hygiene & Tropical Medicine, London, United Kingdom.

If facial hygiene practices vary seasonally this could have important implications for the design of interventions for trachoma control. This observational study was conducted to explore seasonal variation in hygiene behaviours in 9 households with at least one child aged 1-9 years-of-age in the West Arsi zone in rural Oromia, Ethiopia. Sixty-one household members were observed intensively over two days in the dry season (January), the rainy season (July) and during the harvest period (October) in 2018. Read More

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Epidemiological Investigation and Risk Factor Analysis of Acute Hemorrhagic Conjunctivitis in Huangshi Port District, Huangshi City.

Juan Liu Hui Zhang

Comput Math Methods Med 2022 2;2022:3009589. Epub 2022 May 2.

Technical Service Center, Kunming Center for Disease Control and Prevention, Kunming, Yunnan 650034, China.

Objective: This study is aimed at investigating the epidemiology and risk factors of acute hemorrhagic conjunctivitis (pinkeye) in Huangshi Port District of Huangshi City.

Methods: A total of 593 cases of acute hemorrhagic conjunctivitis from January 2019 to December 2021 were selected as the observation group. The epidemiological characteristics (age of onset, season, occupation, clinical manifestations, and etiological characteristics) were analyzed. Read More

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Prevalence of active trachoma and associated factors among school age children in Debre Tabor Town, Northwest Ethiopia, 2019: a community based cross-sectional study.

Ital J Pediatr 2022 May 3;48(1):61. Epub 2022 May 3.

Department of Environmental Health, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.

Background: Trachoma is an infectious eye disease caused by Chlamydial trachomatis. It is a major health problem in poor nations, notably in Sub-Saharan Africa. Despite the severity of the problem, there was a scarcity of data on trachoma prevalence and associated factors among school-aged children in Debre Tabor town following SAFE and MDA. Read More

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Age-specific associations of early daycare, older siblings, severe airway infection, and preterm birth with subsequent atopic diseases.

Pediatr Allergy Immunol 2022 04;33(4):e13771

Department of Pediatrics, Jikei University Katsushika Medical Center, Tokyo, Japan.

Background: The effects of infection and developmental adaptations in infancy on the prevalence of subsequent atopy-related diseases at different ages during childhood are not fully determined. This study aims to examine the similarities and differences in the age-specific association of asthma, allergic rhinitis/conjunctivitis, and atopic dermatitis with early-life infection-related factors (i.e. Read More

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A national survey integrating clinical, laboratory, and WASH data to determine the typology of trachoma in Nauru.

PLoS Negl Trop Dis 2022 04 19;16(4):e0010275. Epub 2022 Apr 19.

The Kirby Institute, University of New South Wales, Sydney, Australia.

Background: The epidemiology of trachoma in several Pacific Islands differs from other endemic settings, in that there is a high prevalence of clinical signs of trachoma, particularly trachomatous inflammation-follicular (TF), but few cases of trichiasis and limited evidence of ocular chlamydial infection. This so-called "Pacific enigma" has led to uncertainty regarding the appropriate public health response. In 2019 alongside Nauru's national trachoma population survey, we performed bacteriological and serological assessments of children to better understand the typology of trachoma and to determine whether there is a need for trachoma interventions. Read More

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Community-level trachoma ecological associations and the use of geospatial analysis methods: A systematic review.

PLoS Negl Trop Dis 2022 04 8;16(4):e0010272. Epub 2022 Apr 8.

London School of Hygiene & Tropical Medicine, London, United Kingdom.

Background: Trachoma is targeted for global elimination as a public health problem by 2030. Understanding individual, household, or community-associated factors that may lead to continued transmission or risk of recrudescence in areas where elimination has previously been achieved, is essential in reaching and maintaining trachoma elimination. We aimed to identify climatic, demographic, environmental, infrastructural, and socioeconomic factors associated in the literature with trachoma at community-level and assess the strength of their association with trachoma. Read More

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The Gambia has eliminated trachoma as a public health problem: Challenges and successes.

PLoS Negl Trop Dis 2022 03 28;16(3):e0010282. Epub 2022 Mar 28.

Kilimanjaro Centre for Community Ophthalmology, Division of Ophthalmology, University of Cape Town, Cape Town, South Africa.

Trachoma is the leading infectious cause of blindness in the world and has been known to be a major public health problem in The Gambia for over 60 years. Nationwide blindness surveys, including trachoma, in 1986 and 1996 provided the foundation for a comprehensive plan to implement a trachoma elimination strategy. Impact and pre-validation surveillance surveys in 2011-13 demonstrated that active trachoma was below WHO threshold for elimination but trichiasis remained a public health problem. Read More

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Approach to conjunctivitis in newborns.

BMJ 2022 03 23;376:e068023. Epub 2022 Mar 23.

Bristol Eye Hospital, University Hospitals Bristol NHS Foundation Trust, Bristol, UK.

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Global progress toward the elimination of active trachoma: an analysis of 38 countries.

Lancet Glob Health 2022 04;10(4):e491-e500

Zimbabwe Ministry of Health, Harare, Zimbabwe.

Background: Global elimination of trachoma as a public health problem was targeted for 2020. We reviewed progress towards the elimination of active trachoma by country and geographical group.

Methods: In this retrospective analysis of national survey and implementation data, all countries ever known to be endemic for trachoma that had either implemented at least one trachoma impact survey shown in the publicly available Trachoma Atlas, or are in Africa were invited to participate in this study. Read More

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Predicting future community-level ocular Chlamydia trachomatis infection prevalence using serological, clinical, molecular, and geospatial data.

PLoS Negl Trop Dis 2022 03 11;16(3):e0010273. Epub 2022 Mar 11.

Francis I. Proctor Foundation, University of California, San Francisco, California, United States of America.

Trachoma is an infectious disease characterized by repeated exposures to Chlamydia trachomatis (Ct) that may ultimately lead to blindness. Efficient identification of communities with high infection burden could help target more intensive control efforts. We hypothesized that IgG seroprevalence in combination with geospatial layers, machine learning, and model-based geostatistics would be able to accurately predict future community-level ocular Ct infections detected by PCR. Read More

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Epidemiological trends and sociodemographic factors associated with acute hemorrhagic conjunctivitis in mainland China from 2004 to 2018.

Virol J 2022 03 1;19(1):34. Epub 2022 Mar 1.

Institute of Chronic and Non-Communicable Disease Control and Prevention, Hubei Provincial Center for Disease Control and Prevention, No. 35 Zhuodaoquan North Road, Hongshan District, Wuhan, 430079, China.

Background: Acute hemorrhagic conjunctivitis (AHC) is classified as a class C notifiable infectious disease in China and poses a great threat to public health. This study aimed to investigate the epidemiological trends and hotspots of AHC in mainland China. Sociodemographic factors that could contribute to early warning of AHC were further explored. Read More

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Clinical Presentation, Investigation and Control of an Outbreak of Adenoviral Conjunctivitis in a Neonatal Unit at a Tertiary Hospital.

Pediatr Infect Dis J 2022 03;41(3):243-247

Department of Virology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Background: Nosocomial spread of adenovirus infection has been reported in neonatal, pediatric and adult medical units. This nonenveloped and hardy virus is resistant to numerous disinfectants thus posing a challenge for control and prevention of adenovirus infections in health care settings.

Methods: An epidemiologic outbreak investigation revealed an adenoviral outbreak in the neonatal nursery as well as in the neonatal screening outpatient department for Retinopathy of Prematurity (ROP). Read More

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Severe ophthalmia neonatorum in Southwest China: a 5-year review of demographics, microbiological results, and risk factors.

Int Ophthalmol 2022 Jan 15. Epub 2022 Jan 15.

Department of Ophthalmology, Ministry of Education Key Laboratory of Child Development and Disorders, China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Children's Hospital of Chongqing Medical University, 136, Zhongshan 2nd RD, Yuzhong District, Chongqing,, 400014, China.

Purpose: To evaluate the microbiological characteristics and risk factors of severe ophthalmia neonatorum (ON) in Southwest China.

Methods: In this retrospective review, data on demography, microbiological results, and risk factors were analyzed. Data were obtained from medical records of patients with severe ON treated at Children's Hospital of Chongqing Medical University from January 2015 to December 2019. Read More

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January 2022

Bacterial eye infections associated with sexual transmission infections: A review.

Arch Soc Esp Oftalmol (Engl Ed) 2022 Jan 23;97(1):17-27. Epub 2021 Nov 23.

Laboratorio de Microbiología Molecular, Escuela de Tecnología Médica, Universidad Austral de Chile, Puerto Montt, Chile. Electronic address:

The objective of this work was to collect updated information on Treponema pallidum, Chlamydia trachomatis and Neisseria gonorrhoeae, causing sexually transmitted infections (STIs) and etiological agents of eye infections, to provide relevant information on this public health problem. For this, a bibliographic review was carried out using different electronic databases such as: PubMed central, google academic, Lilacs, Scopus, Science Direct and Scielo, between March 2009 and August 2019. According to the WHO, more than a million people a day contract a sexually transmitted infection. Read More

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January 2022

OPHTHALMIA NEONATORUM in Italy: it is time for change.

Ital J Pediatr 2021 Dec 18;47(1):238. Epub 2021 Dec 18.

Neonatal Intensive Care Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Ophthalmia neonatorum (ON) refers to any conjunctivitis occurring in the first 28 days of life. In the past Neisseria gonorrhoeae was the most common cause of ON. It decreased with the introduction of prophylaxis at birth with the instillation of silver nitrate 2% (the Credè's method of prophylaxis). Read More

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December 2021

Water, sanitation, and hygiene for control of trachoma in Ethiopia (WUHA): a two-arm, parallel-group, cluster-randomised trial.

Lancet Glob Health 2022 01;10(1):e87-e95

Francis I Proctor Foundation, University of California, San Francisco, CA, USA; Department of Ophthalmology, University of California, San Francisco, CA, USA. Electronic address:

Background: WHO promotes the SAFE strategy for the elimination of trachoma as a public health programme, which promotes surgery for trichiasis (ie, the S component), antibiotics to clear the ocular strains of chlamydia that cause trachoma (the A component), facial cleanliness to prevent transmission of secretions (the F component), and environmental improvements to provide water for washing and sanitation facilities (the E component). However, little evidence is available from randomised trials to support the efficacy of interventions targeting the F and E components of the strategy. We aimed to determine whether an integrated water, sanitation, and hygiene (WASH) intervention prevents the transmission of trachoma. Read More

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January 2022

Herpes Simplex Virus 2 Blepharokeratoconjunctivitis.

Curr Eye Res 2022 Mar 29;47(3):361-364. Epub 2021 Dec 29.

Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.

Purpose: To retrospectively review the clinical characteristics of patients with herpes simplex virus type 2 (HSV-2) blepharokeratoconjunctivitis.

Methods: Laboratory-proven HSV-2 blepharokeratoconjunctivitis cases were reviewed between 1995 and 2021.

Results: Ten of 725 (1. Read More

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Changing hygiene behaviours: a cluster-randomized trial, Ethiopia.

Bull World Health Organ 2021 Nov 30;99(11):762-772A. Epub 2021 Aug 30.

Francis I Proctor Foundation, University of California San Francisco, 490 Illinois Street, Floor 2, Box 0944, San Francisco, CA 94158, United States of America (USA).

Objective: To determine whether a water, sanitation and hygiene intervention could change hygiene behaviours thought to be important for trachoma control.

Methods: We conducted a cluster-randomized trial in rural Ethiopia from 9 November 2015 to 5 March 2019. We randomized 20 clusters to an intervention consisting of water and sanitation infrastructure and hygiene promotion and 20 clusters to no intervention. Read More

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November 2021

In water or on land? Evaluation of perinatal and neonatal outcomes of water births in low-risk women.

Ceska Gynekol 2021 ;86(5):311-317

Objective: Evaluate perinatal and neonatal outcomes comparing a water birth to regular childbirth in low-risk women. File and methods: Retrospective analysis of a set of childbirths that took place over a given period of time in the hospital and health center of Havířov. We compared a set of low-risk women that had given a water birth to a selected control group of low-risk women that had given regular childbirth. Read More

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November 2021


Wiad Lek 2021 ;74(9 cz 1):2025-2032


Objective: The aim: To obtain the estimates of the сurrent incidence rate of perinatal infections, risk factors, as well as their associated impact on mortality and determine the antimicrobial resistance of responsible pathogens in Ukraine.

Patients And Methods: Materials and methods: We performed a multicentre retrospective cohort study was based on surveillance data. This study included infants aged 0 to 6 days delivered in 2017-2019 at 11 Ukrainian regional perinatal centers. Read More

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November 2021

Population-Based Prevalence of Ocular Chlamydia trachomatis Infection among Infants in the Trachoma Endemic Amhara Region, Ethiopia.

Am J Trop Med Hyg 2021 10 25;106(1):62-65. Epub 2021 Oct 25.

Trachoma Control Program, The Carter Center, Atlanta, Georgia.

Infants ages < 6 months do not receive azithromycin as part of trachoma control and thus may serve as an infection reservoir in persistently endemic districts. The aim of this study was to determine the population-based Chlamydia trachomatis infection prevalence and infectious load among infants ages 1-12 months in persistently trachoma endemic districts in Amhara, Ethiopia. Across six districts, 475 infants were enumerated, and of these 464 (97. Read More

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October 2021

Lacrimal Gland Hypoplasia and Corneal Anesthesia in MIRAGE Syndrome: A Case Report and Literature Review.

Cornea 2021 Oct 23. Epub 2021 Oct 23.

Schulich School of Medicine and Dentistry, Western University, London, ON, Canada; Department of Ophthalmology, University of Montreal, Montreal, QC, Canada; and Centre Hospitalier Universitaire Sainte-Justine, Montreal, QC, Canada.

Purpose: The purpose of this report was to describe the ocular findings in Myelodysplasia, Infection, Restriction of growth, Adrenal hypoplasia, Genital problems, and Enteropathy (MIRAGE) syndrome, a multisystem congenital disorder.

Methods: This was a case report and literature review.

Results: An infant with MIRAGE syndrome (combined immunodeficiency with recurrent infections, growth restriction, adrenal insufficiency, 46,XY karyotype with hypovirilization, dysphagia, gastroesophageal reflux disease, and dysautonomia) underwent ophthalmological evaluation because of persistent conjunctivitis during his 8-month admission in the neonatal intensive care unit. Read More

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October 2021

Effectiveness of azithromycin mass drug administration on trachoma: a systematic review.

Chin Med J (Engl) 2021 Sep 16;134(24):2944-2953. Epub 2021 Sep 16.

Key Laboratory of Obstetrics & Gynecologic and Pediatric Diseases and Birth Defects of the Ministry of Education, Sichuan University, Chengdu, Sichuan 610041, China.

Backgrounds: Azithromycin mass drug administration (MDA) is a key part of the strategy for controlling trachoma. This systematic review aimed to comprehensively summarize the present studies of azithromycin MDA on trachoma; provide an overview of the impact of azithromycin MDA on trachoma in different districts; and explore the possible methods to enhance the effectiveness of azithromycin MDA in hyperendemic districts.

Methods: PubMed, Embase, the Cochrane Central Register of Controlled Trials, Web of Science, and ClinicalTrials. Read More

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September 2021

Cochrane corner: interventions for preventing ophthalmia neonatorum.

Eye (Lond) 2022 02 12;36(2):356-357. Epub 2021 Oct 12.

International Centre of Eye Health, Department of Clinical Research, London School of Hygiene & Tropical Medicine, London, WC1V 7HT, UK.

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February 2022

The clinical course and short-term health outcomes of multisystem inflammatory syndrome in children in the single pediatric rheumatology center.

Postgrad Med 2021 Nov 17;133(8):994-1000. Epub 2021 Oct 17.

Department of Pediatric Rheumatology, Umraniye Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.

Objectives: Multisystem inflammatory syndrome in children (MIS-C) is a rare but severe condition resulting in excessive response of the immune system after SARS-CoV-2 infection. We report a single-center cohort of children with MIS-C, describing the spectrum of presentation, therapies, clinical course, and short-term outcomes.

Methods: This is a prospective observational study from to a tertiary pediatric rheumatology center including patients (aged 1 month to 21 years) diagnosed with MIS-C between April 2020-April 2021. Read More

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November 2021