1,963 results match your criteria Conjunctivitis Neonatal


Haemolacria: a case of pseudomembranous conjunctivitis in a neonate.

BMJ Case Rep 2020 Jun 30;13(6). Epub 2020 Jun 30.

Department of Adolescent and Child Health, Mater Dei Hospital, Msida, Malta.

We report an unusual case of an 11-day-old neonate presenting with haemolacria on a background of sticky conjunctival discharge. This was secondary to pseudomembranous conjunctivitis which responded well to systemic erythromycin. Early appropriate treatment is important to prevent progression of the ophthalmic infection, which could lead to blindness, and to prevent other manifestations of neonatal chlamydial infection, particularly pneumonia, which could be fatal. Read More

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http://dx.doi.org/10.1136/bcr-2020-235110DOI Listing

Cardiac MRI of Children with Multisystem Inflammatory Syndrome (MIS-C) Associated with COVID-19: Case Series.

Radiology 2020 Jun 9:202288. Epub 2020 Jun 9.

From the Department of imaging, Hôpital Trousseau - Assistance Publique-Hôpitaux Parisiens (AP-HP), Sorbonne Université, Paris, France (E.B., C.S., H.D.L.P.), Laboratoire d'Imagerie Biomédicale, Sorbonne Université, INSERM, CNRS, Paris, France (E.B., A.R.), Pediatric cardiovascular Unit, Hôpital Trousseau - Assistance Publique-Hôpitaux Parisiens (AP-HP), Sorbonne Université, Paris, France (P.P., A.R.), Department of Cardiovascular and Thoracic Imaging and Interventional Radiology, Institute of Cardiology, Hôpital Pitié-Salpêtrière - Assistance Publique-Hôpitaux Parisiens (AP-HP) Sorbonne Université, Paris, France (A.R.), Neonatal and Pediatric Intensive Care Unit, Hôpital Trousseau - Assistance Publique-Hôpitaux Parisiens (AP-HP), Sorbonne Université, Paris, France (L.T., Y.L.), Laboratoire INSERM U955- PHYDES-IMRB - Stratégies pharmacologiques et thérapeutiques de l'ischémie myocardique et l'insuffisance coronaire- Ecole Vétérinaire, Maisons-Alfort (Y.L.), Laboratoire de virologie, Hôpital Trousseau - Assistance Publique-Hôpitaux Parisiens (AP-HP), Sorbonne Université, Paris, France (A.S.), Department of Pediatrics, Hôpital Trousseau - Assistance Publique-Hôpitaux Parisiens (AP-HP), Sorbonne Université, Paris, France (M.L.), Pediatric Emergency Department, Hôpital Trousseau - Assistance Publique-Hôpitaux Parisiens (AP-HP), Sorbonne Université, Paris, France (R.G.).

This case series examines cardiac MRI findings in four children and adolescents admitted to intensive care in April 2020 for multisystem inflammatory syndrome and Kawasaki disease-like features related to COVID-19. Acute myocarditis occurred less than 1 week after onset of fever and gastrointestinal symptoms. Physical examination showed rash and cheilitis/conjunctivitis. Read More

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http://dx.doi.org/10.1148/radiol.2020202288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294821PMC

Acute myocarditis and multisystem inflammatory emerging disease following SARS-CoV-2 infection in critically ill children.

Ann Intensive Care 2020 Jun 1;10(1):69. Epub 2020 Jun 1.

Pediatric Intensive Care Unit, Necker-Enfants-Malades University Hospital, Assistance Publique-Hôpitaux de Paris, Paris University, EA7323, 75006, Paris, France.

Background: A recent increase in children admitted with hypotensive shock and fever in the context of the COVID-19 outbreak requires an urgent characterization and assessment of the involvement of SARS-CoV-2 infection. This is a case series performed at 4 academic tertiary care centers in Paris of all the children admitted to the pediatric intensive care unit (PICU) with shock, fever and suspected SARS-CoV-2 infection between April 15th and April 27th, 2020.

Results: 20 critically ill children admitted for shock had an acute myocarditis (left ventricular ejection fraction, 35% (25-55); troponin, 269 ng/mL (31-4607)), and arterial hypotension with mainly vasoplegic clinical presentation. Read More

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http://dx.doi.org/10.1186/s13613-020-00690-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266128PMC

Maternal-Fetal Interplay in Zika Virus Infection and Adverse Perinatal Outcomes.

Front Immunol 2020 14;11:175. Epub 2020 Feb 14.

Laboratory of Dermatology and Immunodeficiencies, LIM-56, Department of Dermatology, School of Medicine and Institute of Tropical Medicine of São Paulo, University of São Paulo, São Paulo, Brazil.

During pregnancy, the organization of complex tolerance mechanisms occurs to assure non-rejection of the semiallogeneic fetus. Pregnancy is a period of vulnerability to some viral infections, mainly during the first and second trimesters, that may cause congenital damage to the fetus. Recently, Zika virus (ZIKV) infection has gained great notoriety due to the occurrence of congenital ZIKV syndrome, characterized by fetal microcephaly, which results from the ability of ZIKV to infect placental cells and neural precursors in the fetus. Read More

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http://dx.doi.org/10.3389/fimmu.2020.00175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033814PMC
February 2020

Vision Screening in Infants Attending Immunization Clinics in a Developing Country.

J Prim Care Community Health 2020 Jan-Dec;11:2150132720907430

University of Nigeria Teaching Hospital, Enugu, Nigeria.

Vision screening in infants is an important part of the medical care of children as some eye abnormalities, if not treated in the first few months or years of life, can lead to irreversible vision loss. The objective of this cross-sectional, descriptive study was to identify ocular anomalies among infants attending immunization clinics in Nigeria and refer promptly and appropriately. Infants were screened across 6 immunization clinics. Read More

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http://dx.doi.org/10.1177/2150132720907430DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045294PMC
February 2020

Serratia marcescens in the neonatal intensive care unit: A cluster investigation using molecular methods.

J Infect Public Health 2020 Jul 26;13(7):1006-1011. Epub 2019 Dec 26.

Duke-NUS Graduate Medical School, Singapore; Infectious Diseases Service, KK Women's & Children's Hospital, Singapore. Electronic address:

Background: Serratia marcescens (S. marcescens) is associated with nosocomial infections with significant morbidity and mortality in the neonatal intensive care units (NICU). We describe the control of a multi-clonal S. Read More

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http://dx.doi.org/10.1016/j.jiph.2019.12.003DOI Listing

Evidence for contamination with C. trachomatis in the household environment of children with active Trachoma: A cross-sectional study in Kongwa, Tanzania.

PLoS Negl Trop Dis 2019 12 23;13(12):e0007834. Epub 2019 Dec 23.

Division of Infectious Diseases, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America.

Background: Trachoma, a conjunctivitis caused by repeated infections with Chlamydia trachomatis, remains a significant cause of blindness worldwide. While mass treatments with azithromycin decreases disease and infection, re-emergence occurs, indicating that elimination may require other sustainable interventions. Environmental changes largely focus on facial hygiene and latrines, but further work to identify other possible transmission targets are needed. Read More

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http://dx.doi.org/10.1371/journal.pntd.0007834DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946162PMC
December 2019

Comparison between two ocular cleansing modalities in a population of newborns admitted to Neonatal Intensive Care Unit with clinical signs of conjunctivitis: a randomized controlled trial.

Minerva Pediatr 2019 Dec;71(6):500-504

Neonatal Intensive Care Unit, V. Buzzi Children's Hospital, ASST-FBF-Sacco, Milan, Italy -

Background: Neonatal conjunctivitis is frequent and could benefit from daily cleansing with saline. Anyway super infections can occur and therefore antibiotics are frequently needed. Recently alternative therapies (e. Read More

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http://dx.doi.org/10.23736/S0026-4946.19.05659-7DOI Listing
December 2019

Phylogenetic and Epidemiological Analysis of Measles Viruses in Shenzhen, China from January 2015 to July 2019.

Med Sci Monit 2019 Dec 4;25:9245-9254. Epub 2019 Dec 4.

Department of Pharmacy, Shenzhen Children's Hospital, Shenzhen, Guangdong, China (mainland).

BACKGROUND Measles morbidity and mortality were significantly reduced after the measles vaccine was introduced in China in 1965. However, measles outbreaks easily occur in densely populated areas, especially where there is no universal vaccination. The outbreak that occurred in Shenzhen, the Chinese city with the largest internal immigration, provides a lesson in measles virus mutation and measles prevention. Read More

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http://dx.doi.org/10.12659/MSM.920614DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6911309PMC
December 2019

Bacteriology and Antimicrobial Susceptibility Patterns of Childhood Acute Bacterial Conjunctivitis in Western Greece.

Med Hypothesis Discov Innov Ophthalmol 2019 1;8(4):266-271. Epub 2019 Oct 1.

Department of Pediatrics, ''Karamandaneio'' General Pediatric Hospital, Patras, Greece.

Acute bacterial conjunctivitis is a common, highly contagious infection in children and is usually treated empirically with broad spectrum topical antibiotics. In the current study we investigated bacteriology and antibiotic susceptibility patterns in childhood acute bacterial conjunctivitis in Western Greece. We conducted a retrospective analysis of presumed acute bacterial conjunctivitis cases in ''Karamandaneio'' Pediatric General Hospital of Patras, Western Greece, between February 1, 2013 and January 31, 2018. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778672PMC
October 2019

Prevalence of active trachoma and associated factors among children aged 1 to 9 years in rural communities of Lemo district, southern Ethiopia: community based cross sectional study.

BMC Infect Dis 2019 Oct 24;19(1):886. Epub 2019 Oct 24.

Public health emergency management, Hadiya zone health department, Hossana, Ethiopia.

Background: Trachoma, caused by Chlamydia trachomatis is the leading infectious cause of blindness. It is transmitted via personal contact with infected ocular and nasal secretions by hands, fomites and eye- seeking flies. Active trachoma is more common among children aged 1 to 9 years. Read More

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http://dx.doi.org/10.1186/s12879-019-4495-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813116PMC
October 2019
2.613 Impact Factor

Neonatal ophthalmia in Mali.

Med Sante Trop 2019 Aug;29(3):256-258

Centre hospitalier et universitaire de l'Institut d'ophtalmologie tropicale de l'Afrique (CHU-IOTA), BP : 1428, Bamako, Mali.

A newborn 3 hours old newborn presented bilateral eyelid edema with erythema and inflammatory hypertrophy of the palpebral conjunctiva. PCR of the conjunctival swabbing showed the presence of Chlamydia trachomatis DNA. Treatment with erythromycin suspension 125 mg/5 ml was initiated, supplemented by topical application of oxytetracycline ointment 1% and Azyter eye drops. Read More

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http://dx.doi.org/10.1684/mst.2019.0930DOI Listing

Utilization of Secondary Eye Care Services in Western Kenya.

Int J Environ Res Public Health 2019 09 12;16(18). Epub 2019 Sep 12.

International Centre for Eye Health, Clinical Research Department, London School of Hygiene & Tropical Medicine, London WC1E 7HT, UK.

Eye care provision is currently insufficient to meet the population's eye health needs in Kenya. Many people remain unnecessarily visually impaired or at risk of becoming so due to treatable or preventable conditions. A lack of access and awareness of services are key barriers, in large part due to their being too few eye care providers in the health system for this unmet need. Read More

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http://dx.doi.org/10.3390/ijerph16183371DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766006PMC
September 2019
1 Read

Antibacterial resistance in ophthalmic infections: a multi-centre analysis across UK care settings.

BMC Infect Dis 2019 Sep 3;19(1):768. Epub 2019 Sep 3.

Imperial College London, South Kensington Campus, London, SW7 2AZ, UK.

Background: Bacterial ophthalmic infections are common. Empirical treatment with topical broad-spectrum antibiotics is recommended for severe cases. Antimicrobial resistance (AMR) to agents used for bacterial ophthalmic infections make it increasingly important to consider changing resistance patterns when prescribing, however UK data in this area are lacking. Read More

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http://dx.doi.org/10.1186/s12879-019-4418-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724305PMC
September 2019

Ocular Prophylaxis for Gonococcal Ophthalmia Neonatorum: Recommendation Statement.

Authors:

Am Fam Physician 2019 08;100(4):236-238

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Gonococcal conjunctivitis after incomplete treatment of gonococcal urethritis.

Infect Drug Resist 2019 23;12:1381-1384. Epub 2019 May 23.

Department of Dermatology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100069, People's Republic of China.

Gonococcal conjunctivitis is due to ophthalmic infection with Neisseria gonorrhoeae, and it is considered rare in the non-neonatal populations, particularly its association with gonorrhea and chlamydial urethritis in the same patient. Here we describe a 27-year-old newly married man presenting gonococcal conjunctivitis and discuss the selection of antibiotic drugs associated with its course. Read More

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http://dx.doi.org/10.2147/IDR.S199163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537035PMC
May 2019
15 Reads

Frequency of Ocular Diseases in Infants at a Tertiary Care Hospital.

Korean J Ophthalmol 2019 Jun;33(3):287-293

Department of Ophthalmology, Abbasi Shaheed Hospital, Karachi Medical and Dental College, Karachi, Pakistan.

Purpose: To determine the frequency of ocular diseases in infants visiting the ophthalmology department of a tertiary care hospital.

Methods: This was a cross-sectional descriptive study conducted in the department of ophthalmology, Abbasi Shaheed Hospital, from January 2015 to May 2016. The study included 377 infants ranging in age from 1 day to less than 1 year who were, selected by a nonprobability consecutive sampling technique. Read More

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http://dx.doi.org/10.3341/kjo.2017.0142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557792PMC
June 2019
19 Reads

Linear growth in preschool children treated with mass azithromycin distributions for trachoma: A cluster-randomized trial.

PLoS Negl Trop Dis 2019 06 5;13(6):e0007442. Epub 2019 Jun 5.

Francis I. Proctor Foundation, University of California, San Francisco, San Francisco, California, United States of America.

Background: Mass azithromycin distributions have been shown to reduce mortality among pre-school children in sub-Saharan Africa. It is unclear what mediates this mortality reduction, but one possibility is that antibiotics function as growth promoters for young children.

Methods And Findings: 24 rural Ethiopian communities that had received biannual mass azithromycin distributions over the previous four years were enrolled in a parallel-group, cluster-randomized trial. Read More

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http://dx.doi.org/10.1371/journal.pntd.0007442DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550377PMC
June 2019
4 Reads

[Conjunctivitis by Capnocytophaga ochracea in a two weeks newborn].

Rev Esp Quimioter 2019 Jun 6;32(3):284-285. Epub 2019 May 6.

María Aroca Ferri, Servicio de Microbiología, Hospital Universitario Insular de Gran Canaria. Avda.Marítima del Sur s/n, 35016 Las Palmas de Gran Canaria. Spain.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609935PMC
June 2019
1 Read

Maternal infection with Zika virus and prevalence of congenital disorders in infants: systematic review and meta-analysis.

Can J Public Health 2019 10 10;110(5):638-648. Epub 2019 May 10.

Public Health Risk Sciences Division, Public Health Agency of Canada, 180 Queen Street West, Rm 8-15, Toronto, ON, M5V 3L7, Canada.

Objective: Zika virus (ZIKV) infection is a vector-borne disease that can be transmitted sexually and vertically. The vertical transmission of the virus may lead to congenital Zika syndrome in infants. The aim of this study is to conduct a systematic review and meta-analysis of published reports documenting the prevalence of congenital Zika-related disorders in infants of mothers infected with ZIKV during pregnancy. Read More

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http://dx.doi.org/10.17269/s41997-019-00215-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964464PMC
October 2019
2 Reads

Prevalence of active trachoma and associated risk factors among children of the pastoralist population in Madda Walabu rural district, Southeast Ethiopia: a community-based cross-sectional study.

BMC Infect Dis 2019 Apr 29;19(1):353. Epub 2019 Apr 29.

Department of Public Health, Madda Walabu University Goba Referral Hospital, Bale Goba, Ethiopia.

Background: In developing countries particularly in sub-Saharan Africa trachoma is still a public health concern. Ethiopia is the most affected of all and bears the highest burden of active trachoma. In spite of this, the prevalence of active trachoma among the pastoralist population in Ethiopia not yet disclosed. Read More

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https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128
Publisher Site
http://dx.doi.org/10.1186/s12879-019-3992-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489250PMC
April 2019
32 Reads
2.613 Impact Factor

Lipidomic Analysis Reveals Serum Alteration of Plasmalogens in Patients Infected With ZIKA Virus.

Front Microbiol 2019 12;10:753. Epub 2019 Apr 12.

Laboratório de Patologia Experimental, Instituto Gonçalo Moniz, Salvador, Brazil.

Zika virus (ZIKV) is an arthropod-borne virus (arbovirus) in the genus of the family. Since the large outbreaks in French Polynesia in 2013-2014 and in Brazil in 2015, ZIKV has been considered a new public health threat. Similar to other related flavivirus, ZIKV is associated with mild and self-limiting symptoms such as rash, pruritus, prostration, headache, arthralgia, myalgia, conjunctivitis, lower back pain and, when present, a short-term low grade fever. Read More

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http://dx.doi.org/10.3389/fmicb.2019.00753DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474330PMC
April 2019
3 Reads
3.941 Impact Factor

Neonatal Conjunctivitis Caused by Neisseria meningitidis US Urethritis Clade, New York, USA, August 2017.

Emerg Infect Dis 2019 05;25(5):972-975

We characterized a case of neonatal conjunctivitis in New York, USA, caused by Neisseria meningitidis by using whole-genome sequencing. The case was a rare occurrence, and the isolate obtained belonged to an emerging clade (N. meningitidis US nongroupable urethritis) associated with an increase in cases of urethritis since 2015. Read More

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http://dx.doi.org/10.3201/eid2505.181631DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478211PMC
May 2019
11 Reads

Community-level Association between Clinical Trachoma and Ocular Chlamydia Infection after MASS Azithromycin Distribution in a Mesoendemic Region of Niger.

Ophthalmic Epidemiol 2019 08 8;26(4):231-237. Epub 2019 Apr 8.

b Francis I. Proctor Foundation , University of California , San Francisco , USA.

: The clinical sign trachomatous inflammation - follicular (TF) is used to monitor indication for and response to mass azithromycin distribution in trachoma-endemic communities. Here, we assess the relationship between TF, trachomatous inflammation - intense (TI), and infection with ocular over time during annual mass azithromycin distribution. : We used data from a cluster-randomized trial of mass azithromycin distribution for trachoma control in a mesoendemic region of Niger. Read More

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http://dx.doi.org/10.1080/09286586.2019.1597129DOI Listing
August 2019
50 Reads

Mobile technology offers novel insights into the control and treatment of allergic rhinitis: The MASK study.

J Allergy Clin Immunol 2019 07 3;144(1):135-143.e6. Epub 2019 Apr 3.

MACVIA-France, Fondation partenariale FMC VIA-LR, Montpellier, France; University Hospital, Montpellier, France; INSERM U 1168, VIMA: Ageing and chronic diseases Epidemiological and Public Health Approaches, Villejuif, Université Versailles St-Quentin-en-Yvelines, Montigny le Bretonneux, and Euforea, Brussels, Belgium. Electronic address:

Background: Mobile health can be used to generate innovative insights into optimizing treatment to improve allergic rhinitis (AR) control.

Objectives: A cross-sectional real-world observational study was undertaken in 22 countries to complement a pilot study and provide novel information on medication use, disease control, and work productivity in the everyday life of patients with AR.

Methods: A mobile phone app (Allergy Diary, which is freely available on Google Play and Apple stores) was used to collect the data of daily visual analogue scale (VAS) scores for (1) overall allergic symptoms; (2) nasal, ocular, and asthma symptoms; (3) work; and (4) medication use by using a treatment scroll list including all allergy medications (prescribed and over-the-counter) customized for 22 countries. Read More

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http://dx.doi.org/10.1016/j.jaci.2019.01.053DOI Listing
July 2019
72 Reads
11.476 Impact Factor

A Cross-Sectional Study of the Availability of Azithromycin in Local Pharmacies and Associated Antibiotic Resistance in Communities in Kilosa District, Tanzania.

Am J Trop Med Hyg 2019 05;100(5):1105-1109

Dana Center for Preventive Ophthalmology, Johns Hopkins School of Medicine, Baltimore, Maryland.

Mass drug administration (MDA) for trachoma control using azithromycin has generated concern for the development of resistant organisms. However, the contribution from azithromycin available in local pharmacies has not been studied. In Kilosa district, Tanzania, MDA stopped over 4 years ago, and this study sought to determine the availability of azithromycin in local pharmacies and correlate it with azithromycin resistance in children born after MDA. Read More

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http://dx.doi.org/10.4269/ajtmh.18-0747DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6493967PMC
May 2019
7 Reads

Gonococcal ophthalmia neonatorum: a case report.

Med Sante Trop 2018 Nov;28(4):443-445

Institut d'ophtalmologie tropicale de l'Afrique, Bamako, Mali.

A baby born at home 14 hours earlier was brought to the neonatology department with bilateral upper palpebral chemosis with purulent secretions and pseudomembranes, with no general signs of infection. The gram staining of a secretion sample shows the presence of Neisseria gonorrhoeae. Intramuscular ceftriaxone treatment was initiated, combined with topical application of rifamycin, dexamethasone, and oxytetracycline. Read More

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http://dx.doi.org/10.1684/mst.2018.0844DOI Listing
November 2018
6 Reads

Infections in Neonatal Intensive Care Units (NICUs).

Int J Environ Res Public Health 2019 02 20;16(4). Epub 2019 Feb 20.

Department of Health Sciences, University of Genoa, Italy Via Pastore, 1-16132 Genoa, Italy.

belongs to the family Enterobacteriaceae, which is commonly found in water, soil, animals, insects, plants. Although displays relatively low virulence, it causes nosocomial infections and outbreaks in severely immunocompromised or critically ill patients, particularly in settings such as intensive care units (ICUs), especially neonatal units (NICUs). This microorganism gives rise to a wide range of clinical manifestations in newborns: from asymptomatic colonization to keratitis, conjunctivitis, urinary tract infections, pneumonia, surgical wound infections, sepsis, bloodstream infection and meningitis. Read More

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http://dx.doi.org/10.3390/ijerph16040610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406414PMC
February 2019
7 Reads

Zika virus infection in pregnant women in a General Hospital of Veracruz, Mexico.

J Matern Fetal Neonatal Med 2019 Mar 1:1-5. Epub 2019 Mar 1.

b Subdirección de enseñanza e investigación , Hospital Regional de Alta Especialidad de Oaxaca , Oaxaca , México.

Objectives: To characterize the symptomatology of the patients affected by the Zika virus and to determine the incidence of congenital syndrome due to Zika in pregnant women in the city of Veracruz, Mexico.

Methods: Descriptive, retrospective, and longitudinal study. All the patients in gestation period who attended the general hospital from 1 August to 30 November, 2016 and who met the criterion of suspected case of Zika virus infection. Read More

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http://dx.doi.org/10.1080/14767058.2019.1582627DOI Listing
March 2019
9 Reads

Baseline characteristics and clinical symptoms related to respiratory viruses identified among patients presenting with influenza-like illness in primary care.

Clin Microbiol Infect 2019 Sep 29;25(9):1147-1153. Epub 2019 Jan 29.

Sorbonne Université, INSERM, Institut Pierre Louis d'épidémiologie et de Santé publique, Paris, France; Université de Versailles Saint-Quentin-en-Yvelines, UVSQ, UFR de Médecine, Versailles, France; Assistance Publique - Hôpitaux de Paris APHP, Hôpital Ambroise Paré, Service de Médecine Interne, Boulogne Billancourt, France.

Objectives: We aimed to identify patients' clinical characteristics associated with respiratory viruses identified among patients presenting with influenza-like illness (ILI).

Methods: A sample of patients of all ages presenting with ILI was included by physicians of the French Sentinelles network during two seasons (2015/16 and 2016/17). Nasopharyngeal samples were tested for the presence of influenza virus (IV), respiratory syncytial virus (RSV), human rhinovirus (HRV) and human metapneumovirus (HMPV). Read More

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http://dx.doi.org/10.1016/j.cmi.2019.01.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7172742PMC
September 2019
5 Reads
5.768 Impact Factor

Ocular Prophylaxis for Gonococcal Ophthalmia Neonatorum: US Preventive Services Task Force Reaffirmation Recommendation Statement.

JAMA 2019 Jan;321(4):394-398

Tufts University, Medford, Massachusetts.

Importance: In the United States, the rate of gonococcal ophthalmia neonatorum was an estimated 0.4 cases per 100 000 live births per year from 2013 to 2017. Gonococcal ophthalmia neonatorum can cause corneal scarring, ocular perforation, and blindness as early as 24 hours after birth. Read More

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http://dx.doi.org/10.1001/jama.2018.21367DOI Listing
January 2019
11 Reads

Prevention of Gonococcal Eye Infection in Newborns.

Authors:
Jill Jin

JAMA 2019 01;321(4):414

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http://dx.doi.org/10.1001/jama.2018.21434DOI Listing
January 2019
6 Reads

Ocular Prophylaxis for Gonococcal Ophthalmia Neonatorum: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force.

JAMA 2019 01;321(4):404-406

Kaiser Permanente Research Affiliates Evidence-based Practice Center, Kaiser Permanente Center for Health Research, Portland, Oregon.

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http://dx.doi.org/10.1001/jama.2018.17847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439759PMC
January 2019
7 Reads

Community-level chlamydial serology for assessing trachoma elimination in trachoma-endemic Niger.

PLoS Negl Trop Dis 2019 01 28;13(1):e0007127. Epub 2019 Jan 28.

Divison of Parasitic Diseases and Malaria, Centers for Disease Prevention and Control, Atlanta, Georgia, United States of America.

Background: Program decision-making for trachoma elimination currently relies on conjunctival clinical signs. Antibody tests may provide additional information on the epidemiology of trachoma, particularly in regions where it is disappearing or elimination targets have been met.

Methods: A cluster-randomized trial of mass azithromycin distribution strategies for trachoma elimination was conducted over three years in a mesoendemic region of Niger. Read More

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http://dx.plos.org/10.1371/journal.pntd.0007127
Publisher Site
http://dx.doi.org/10.1371/journal.pntd.0007127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366708PMC
January 2019
40 Reads

Population coverage and factors associated with participation following a mass drug administration of azithromycin for trachoma elimination in Amhara, Ethiopia.

Trop Med Int Health 2019 04 10;24(4):493-501. Epub 2019 Feb 10.

Trachoma Control Program, The Carter Center, Atlanta, GA, USA.

Objectives: Mass drug administration (MDA) with azithromycin is a core component of the WHO-recommended strategy to eliminate trachoma as a public health problem, but low participation rates in MDA campaigns may undermine the effectiveness of this intervention. We explored factors associated with individual MDA participation at the individual, head of household and household levels in Amhara, Ethiopia.

Methods: We conducted four district-level, multilevel cluster random coverage surveys to collect data on self-reported MDA participation and predictors. Read More

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http://dx.doi.org/10.1111/tmi.13208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850572PMC
April 2019
50 Reads

Ophthalmia Neonatorum.

Authors:
Aik-Kah Tan

N Engl J Med 2019 Jan;380(2):e2

Normah Medical Specialist Center, Kuching, Malaysia

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http://dx.doi.org/10.1056/NEJMicm1808613DOI Listing
January 2019
6 Reads

[Right treatment of red eyes - prescription of topical antibiotics for infectious conjunctivitis is still common in Sweden].

Authors:
Tomas Bro

Lakartidningen 2018 12 17;115. Epub 2018 Dec 17.

Region Jönköpings län - Ögonmottagningen Höglandssjukhuset Eksjö, Sweden Region Jönköpings län - Ögonmottagningen Höglandssjukhuset Eksjö, Sweden.

Conjunctivitis is one of the most common ophthalmologic conditions in general medical practice. In most cases, it is self-limiting and do not require topical antibiotic therapy. In a retrospective, observational cohort study during 2013-2017 in a region in Sweden conjunctivitis was diagnosed in 32 000 cases in primary care. Read More

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December 2018
8 Reads

The newborn conjunctival flora at the post delivery 24 hours.

J Curr Ophthalmol 2018 Dec 10;30(4):348-352. Epub 2018 Apr 10.

Department of Microbiology, Kayseri Training and Education Hospital, Kayseri, Turkey.

Purpose: The aim of this study was to investigate the aerobic conjunctival flora of neonates and the effects of delivery type on conjunctival flora development in neonates who were born with normal spontaneous vaginal delivery (SVD) or elective caesarean section (C/S) and who were not given prophylactic antibiotic eye drops after birth.

Methods: This cross-sectional study included 95 healthy newborns. One day after the delivery, conjunctival samples were taken from newborns who were born with normal SVD or elective C/S, and not given prophylactic antibiotic eye drops after birth. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S24522325173014
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http://dx.doi.org/10.1016/j.joco.2018.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276619PMC
December 2018
24 Reads

Neonatal conjunctivitis in the New Zealand Midland region.

N Z Med J 2018 11 30;131(1486):9-17. Epub 2018 Nov 30.

Ophthalmologist, Clinical Senior Lecturer, Ophthalmology Department, Department of Medicine, Hauora Tairawhiti, University of Otago, Gisborne.

Aims: To assess the incidence of chlamydial and gonorrhoeal neonatal conjunctivitis (CON and GON), across six district health boards in the greater Midland region of New Zealand.

Methods: All positive nucleic acid amplification test (NAAT) eye swabs for Chlamydia trachomatis and NAAT and bacterial eye swabs for Neisseria gonorrhoeae in infants under one year of age were retrieved from three laboratories from 2013-2016. Incidence density rates were calculated using births information from Statistics New Zealand. Read More

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November 2018
55 Reads

Neonatal Conjunctivitis Caused by Neisseria cinerea: A Case of Mistaken Identity.

J Pediatric Infect Dis Soc 2019 Nov;8(5):478-480

Division of Pediatric Infectious Diseases, Department of Pediatrics, NYU Winthrop Hospital, Mineola, New York.

We report a case of a 3-day-old boy with Neisseria cinerea conjunctivitis, originally misidentified as Neisseria gonorrhoeae conjunctivitis. Neonates are at increased risk for disseminated gonococcal infection, and physicians should be cognizant of N cinerea and its potential to be mistaken for N gonorrhoeae. Read More

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http://dx.doi.org/10.1093/jpids/piy116DOI Listing
November 2019
38 Reads

Impact of Drinking Water Quality on the Development of Enteroviral Diseases in Korea.

Int J Environ Res Public Health 2018 11 14;15(11). Epub 2018 Nov 14.

Department of Social and Preventive Medicine, School of Medicine, Sungkyunkwan University, Suwon 440-746, Korea.

Enterovirus diseases are fecal-orally transmitted, and its transmission may be closely related with the drinking water quality and other environmental factors. This study aimed to assess the association between environmental factors including drinking water quality and the incidence of enteroviral diseases in metropolitan provinces of Korea. Using monthly number of hand-foot-mouth disease (HFMD), aseptic meningitis (AM) and acute hemorrhage conjunctivitis (AHC) cases, generalized linear Poisson model was applied to estimate the effects of environmental factors on the monthly cases. Read More

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http://www.mdpi.com/1660-4601/15/11/2551
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http://dx.doi.org/10.3390/ijerph15112551DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266091PMC
November 2018
21 Reads

A Survey of Current Prophylactic Treatment for Ophthalmia Neonatorum in Croatia and a Review of International Preventive Practices.

Med Sci Monit 2018 Nov 10;24:8042-8047. Epub 2018 Nov 10.

Psychiatric Hospital "Sveti Ivan", Zagreb, Croatia.

BACKGROUND Ophthalmia neonatorum, or neonatal conjunctivitis, is an acute infection that occurs within the first 28 days of life. This aim of this survey was to evaluate the current methods of preventive treatment for ophthalmia neonatorum in maternity hospitals in Croatia. MATERIAL AND METHODS The annual hospital birth rate in Croatia is approximately 40,000. Read More

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https://www.medscimonit.com/abstract/index/idArt/910705
Publisher Site
http://dx.doi.org/10.12659/MSM.910705DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240167PMC
November 2018
13 Reads

Serratia marcescens outbreak in a neonatology unit of a Spanish tertiary hospital: Risk factors and control measures.

Am J Infect Control 2019 03 2;47(3):271-279. Epub 2018 Nov 2.

Department of Preventive Medicine, La Paz University Hospital, Madrid, Spain.

Background: We describe the investigation undertaken and the measures adopted to control a Serratia marcescens outbreak in the neonatology unit of La Paz University Hospital in Madrid, Spain.

Methods: Weekly rectal and pharyngeal screenings for S marcescens were performed in the neonates starting after detection of the outbreak. Environmental samples and samples from health care workers (HCWs) were obtained for microbiological analysis. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01966553183090
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http://dx.doi.org/10.1016/j.ajic.2018.08.026DOI Listing
March 2019
41 Reads

Innate Immunity Evasion by Enteroviruses Linked to Epidemic Hand-Foot-Mouth Disease.

Front Microbiol 2018 8;9:2422. Epub 2018 Oct 8.

Department of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou, China.

Enterovirus (EV) infections are a major threat to global public health, and are responsible for mild respiratory illness, hand, foot, and mouth disease (HFMD), acute hemorrhagic conjunctivitis, aseptic meningitis, myocarditis, severe neonatal sepsis-like disease, and acute flaccid paralysis epidemic. Among them, HFMD is a common pediatric infectious disease caused by EVs of the family including EV-A71, coxsackieviruses (CV)-A2, CV-A6, CV-A10, and CV-A16. Due to lack of vaccines and specific antiviral therapeutics, millions of children still suffer from HFMD. Read More

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https://www.frontiersin.org/article/10.3389/fmicb.2018.02422
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http://dx.doi.org/10.3389/fmicb.2018.02422DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186807PMC
October 2018
39 Reads

Antibiotic resistance among bacterial conjunctival pathogens collected in the Antibiotic Resistance Monitoring in Ocular Microorganisms (ARMOR) surveillance study.

PLoS One 2018 18;13(10):e0205814. Epub 2018 Oct 18.

Bausch + Lomb, Rochester, New York, United States of America.

The Antibiotic Resistance Monitoring in Ocular Microorganisms (ARMOR) surveillance study evaluates in vitro antibiotic resistance among Staphylococcus aureus, coagulase-negative staphylococci (CoNS), Streptococcus pneumoniae, Pseudomonas aeruginosa, and Haemophilus influenzae isolates from ocular infections. Here we report resistance rates and trends among conjunctival-sourced ocular isolates collected across the US from 2009 through 2016. A total of 1198 conjunctival isolates (483 S. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0205814PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193682PMC
March 2019
7 Reads

Identifying a sufficient core group for trachoma transmission.

PLoS Negl Trop Dis 2018 10 8;12(10):e0006478. Epub 2018 Oct 8.

F.I. Proctor Foundation, University of California San Francisco, San Francisco, CA, United States of America.

Background: In many infectious diseases, a core group of individuals plays a disproportionate role in transmission. If these individuals were effectively prevented from transmitting infection, for example with a perfect vaccine, then the disease would disappear in the remainder of the community. No vaccine has yet proven effective against the ocular strains of chlamydia that cause trachoma. Read More

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http://dx.plos.org/10.1371/journal.pntd.0006478
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http://dx.doi.org/10.1371/journal.pntd.0006478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175502PMC
October 2018
14 Reads

Investigation of an outbreak caused by antibiotic-susceptible Klebsiella oxytoca in a neonatal intensive care unit in Norway.

Acta Paediatr 2019 01 9;108(1):76-82. Epub 2018 Oct 9.

Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.

Aim: Klebsiella spp. have been stated to be the most frequent cause of neonatal intensive care unit (NICU) outbreaks. We report an outbreak of Klebsiella oxytoca in a NICU at a tertiary care hospital in Norway between April 2016 and April 2017. Read More

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http://dx.doi.org/10.1111/apa.14584DOI Listing
January 2019
6 Reads