3,834 results match your criteria Conjunctivitis Bacterial


Two Soft Contact Lenses Retained in the Superior Fornix for 15 Years in a Patient With Unique Orbital Anatomy.

Eye Contact Lens 2019 Apr 9. Epub 2019 Apr 9.

Michigan State University College of Osteopathic Medicine (C.H., J.S.), East Lansing, MI; and Holicki Eye Center and Optical (J.H.), Coldwater, MI.

A 70-year-old white woman presented to her ophthalmologist with bacterial conjunctivitis resistant to treatment. The relationship between the patient's globe and superior orbital rim prompted high clinical suspicion of an occult foreign body as the cause. The following article describes the office visits preceding the discovery of two adhered soft contact lenses lodged in the superior fornix of the right eye that had been hidden for 15 years. Read More

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http://dx.doi.org/10.1097/ICL.0000000000000609DOI Listing

Rosácea infantil.

Bol Med Hosp Infant Mex 2019 ;76(2):95-99

División de Dermatología y Micología, Hospital General Dr. Manuel Gea González, Ciudad de México. México.

Background: Rosacea is a chronic inflammatory skin condition that usually occurs in adults and rarely has been reported in children, although both subtypes share the same clinical characteristics.

Case Report: A 10-year-old female presented dermostosis on the face, affecting cheeks and nose, characterized by erythema, papules, pustules, scars of two years of evolution, as well as bilateral conjunctivitis, blepharitis and corneal opacity. She referred recurrent exacerbations and partial remission of cutaneous lesions and ocular symptoms related to sun exposure. Read More

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http://dx.doi.org/10.24875/BMHIM.18000032DOI Listing
January 2019
1 Read

Measles Pneumonitis.

Adv Respir Med 2019 Mar 4. Epub 2019 Mar 4.

First Academic Department of Pneumonology, Hospital for Diseases of the Chest, "SOTIRIA", Medical School, National and Kapodistrian University of Athens, Greece, Mesogeion 152, Athens, Greece.

Measles represents an acute febrile illness, potentially fatal and highly contagious through the respiratory mode of transmission. Fever combined with one of the following: cough, coryza, conjunctivitis are the first manifestations of the disease. Koplik's spots may also appear on the buccal mucosa providing an opportunity to set the diagnosis even before the appearance of rash. Read More

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http://dx.doi.org/10.5603/ARM.a2019.0010DOI Listing
March 2019
7 Reads

Gonococcal conjunctivitis: A case report.

Authors:
N Anuar N S Idris

Malays Fam Physician 2018 31;13(3):27-28. Epub 2018 Dec 31.

MD USM, MMed (Family Medicine) Family Medicine Department Universiti Sains Malaysia Malaysia.

We report a case of acute gonococcal conjunctivitis in a 36-year-old woman who presented with eye redness and a history of discharge for one month. Prior to presenting to us, she was treated for bacterial conjunctivitis with three courses of local antibiotics by three different clinics after brief assessments and without improvement. The final diagnosis of gonococcal conjunctivitis was made after a complete history was elicited and supported by the presence of Neisseria Gonorrhoeae in the eye swab culture test. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382084PMC
December 2018

Mini Review: Antimicrobial Control of Chlamydial Infections in Animals: Current Practices and Issues.

Front Microbiol 2019 4;10:113. Epub 2019 Feb 4.

The Animal Research Centre, University of the Sunshine Coast, Sippy Downs, QLD, Australia.

are a genus of successful obligate intracellular pathogens spread across humans, wildlife, and domesticated animals. The most common species reported in livestock in this genus are , , , and . Chlamydial infections trigger a series of inflammatory disease-related sequelae including arthritis, conjunctivitis, pneumonia, and abortion. Read More

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http://dx.doi.org/10.3389/fmicb.2019.00113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369208PMC
February 2019
3 Reads

Chronic Conjunctivitis From a Retained Contact Lens.

Eye Contact Lens 2019 Feb 1. Epub 2019 Feb 1.

Department of Ophthalmology and Visual Sciences (J.I.A., A.S., and R.R.S.), Case Western Reserve University and University Hospitals Eye Institute, Cleveland, OH; Skyvision Centers (D.E.W.), Westlake, OH; and Division of Cornea and Refractive Surgery (N.A.A.), Shiley Eye Institute, University of California San Diego, San Diego, CA.

Purpose: To help clinicians diagnose and manage unilateral recalcitrant chronic bacterial conjunctivitis secondary to a retained soft contact lens and describe the first report of Gram-negative bacteria causing this condition.

Methods: Chart review of successive cases presenting with unilateral chronic conjunctivitis with positive cultures and a retained contact lens.

Results: Three cases were identified and described. Read More

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http://Insights.ovid.com/crossref?an=00140068-900000000-9917
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http://dx.doi.org/10.1097/ICL.0000000000000587DOI Listing
February 2019
14 Reads

Ocular Prophylaxis for Gonococcal Ophthalmia Neonatorum: US Preventive Services Task Force Reaffirmation Recommendation Statement.

JAMA 2019 Jan;321(4):394-398

Tufts University, Medford, Massachusetts.

Importance: In the United States, the rate of gonococcal ophthalmia neonatorum was an estimated 0.4 cases per 100 000 live births per year from 2013 to 2017. Gonococcal ophthalmia neonatorum can cause corneal scarring, ocular perforation, and blindness as early as 24 hours after birth. Read More

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http://dx.doi.org/10.1001/jama.2018.21367DOI Listing
January 2019
2 Reads

Prevention of Gonococcal Eye Infection in Newborns.

Authors:
Jill Jin

JAMA 2019 01;321(4):414

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http://dx.doi.org/10.1001/jama.2018.21434DOI Listing
January 2019
1 Read

Ocular Prophylaxis for Gonococcal Ophthalmia Neonatorum: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force.

JAMA 2019 01;321(4):404-406

Kaiser Permanente Research Affiliates Evidence-based Practice Center, Kaiser Permanente Center for Health Research, Portland, Oregon.

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http://dx.doi.org/10.1001/jama.2018.17847DOI Listing
January 2019
2 Reads

Community-level chlamydial serology for assessing trachoma elimination in trachoma-endemic Niger.

PLoS Negl Trop Dis 2019 01 28;13(1):e0007127. Epub 2019 Jan 28.

Divison of Parasitic Diseases and Malaria, Centers for Disease Prevention and Control, Atlanta, Georgia, United States of America.

Background: Program decision-making for trachoma elimination currently relies on conjunctival clinical signs. Antibody tests may provide additional information on the epidemiology of trachoma, particularly in regions where it is disappearing or elimination targets have been met.

Methods: A cluster-randomized trial of mass azithromycin distribution strategies for trachoma elimination was conducted over three years in a mesoendemic region of Niger. Read More

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http://dx.plos.org/10.1371/journal.pntd.0007127
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http://dx.doi.org/10.1371/journal.pntd.0007127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366708PMC
January 2019
10 Reads

Blighia sapida K.D. Koenig: A review on its phytochemistry, pharmacological and nutritional properties.

J Ethnopharmacol 2019 May 24;235:446-459. Epub 2019 Jan 24.

Dept of Pharmaceutics & Pharmaceutical Technology, Faculty of Pharmacy, University of Lagos, Nigeria.

Ethnopharmacological Relevance: Ackee plant (Blighia sapida K. D. Koenig) (Sapindaceae) is used in Sub-Saharan Africa (where it has its origin) and in different parts of the world (The Caribbean, North and South America, Europe). Read More

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http://dx.doi.org/10.1016/j.jep.2019.01.017DOI Listing
May 2019
11 Reads

Preparation and Evaluation of N-Trimethyl Chitosan Nanoparticles of Flurbiprofen for Ocular Delivery.

Curr Eye Res 2019 Jan 11:1-8. Epub 2019 Jan 11.

b SPP School of Pharmacy and Technology Management , NMIMS University , Mumbai , India.

Purpose: A major challenge in ocular therapeutics is poor bioavailability of drug, 1% or even less of the instilled dose is absorbed and frequent administration of conventional products leads to poor adherence to therapy. Hence, the present study is to synthesize N-trimethyl chitosan (TMC), a water-soluble chitosan derivative and to prepare flurbiprofen (FLU):hydroxyl propyl-β-cyclodextrin (HP-β-CD) complex-loaded nanoparticles for treatment of bacterial conjunctivitis which aims to increase the residence time in ocular tissue, thus enhancing patient compliance and improved efficacy.

Methods: TMC was synthesized and characterized by H NMR and FT-IR. Read More

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http://dx.doi.org/10.1080/02713683.2019.1567793DOI Listing
January 2019
1 Read

A severe case of refractory esophageal stenosis induced by nivolumab and responding to tocilizumab therapy.

J Immunother Cancer 2018 Dec 27;6(1):156. Epub 2018 Dec 27.

Department of Medicine, Division of Immunology and Allergy, Lausanne University Hospital CHUV, rue du Bugnon 46, CH-1011, Lausanne, Switzerland.

Background: The prevalence of esophageal stenosis caused by immune checkpoint inhibitors in the context of induced immune mucositis and esophagitis is extremely rare.

Case Presentation: We report the case of a patient with stage IV pulmonary adenocarcinoma treated for 6 months with nivolumab who developed bilateral sterile conjunctivitis followed by oropharyngeal mucositis and esophagitis complicated by a severe esophageal stenosis. The laryngeal margin and hypopharyngeal mucosa appeared highly inflammatory with fibrinous deposits. Read More

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https://jitc.biomedcentral.com/articles/10.1186/s40425-018-0
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http://dx.doi.org/10.1186/s40425-018-0481-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307169PMC
December 2018
23 Reads

[Rehabilitation of Anophthalmic Patients with Prosthetic Eyes in Germany Today - Supply Possibilities, Daily Use, Complications and Psychological Aspects].

Klin Monbl Augenheilkd 2019 Jan 19;236(1):54-62. Epub 2018 Dec 19.

Klinik und Poliklinik für Allgemeine Augenheilkunde, Uniklinik Köln, Köln.

Background: A smooth supply with a visually appealing prosthetic eye after enucleation is not just a cosmetic solution, it is also a key factor in successful social and psychological rehabilitation.

Objectives: This article provides an overview of the current state of medical and ocular care regarding prosthetic eyes in Germany. It focuses mainly on the newest clinical results, daily care, complications, and psychological aspects of wearing prosthetic eyes. Read More

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http://dx.doi.org/10.1055/a-0764-4974DOI Listing
January 2019
2 Reads

[Right treatment of red eyes - prescription of topical antibiotics for infectious conjunctivitis is still common in Sweden].

Authors:
Tomas Bro

Lakartidningen 2018 12 17;115. Epub 2018 Dec 17.

Region Jönköpings län - Ögonmottagningen Höglandssjukhuset Eksjö, Sweden Region Jönköpings län - Ögonmottagningen Höglandssjukhuset Eksjö, Sweden.

Conjunctivitis is one of the most common ophthalmologic conditions in general medical practice. In most cases, it is self-limiting and do not require topical antibiotic therapy. In a retrospective, observational cohort study during 2013-2017 in a region in Sweden conjunctivitis was diagnosed in 32 000 cases in primary care. Read More

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December 2018
2 Reads

The newborn conjunctival flora at the post delivery 24 hours.

J Curr Ophthalmol 2018 Dec 10;30(4):348-352. Epub 2018 Apr 10.

Department of Microbiology, Kayseri Training and Education Hospital, Kayseri, Turkey.

Purpose: The aim of this study was to investigate the aerobic conjunctival flora of neonates and the effects of delivery type on conjunctival flora development in neonates who were born with normal spontaneous vaginal delivery (SVD) or elective caesarean section (C/S) and who were not given prophylactic antibiotic eye drops after birth.

Methods: This cross-sectional study included 95 healthy newborns. One day after the delivery, conjunctival samples were taken from newborns who were born with normal SVD or elective C/S, and not given prophylactic antibiotic eye drops after birth. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S24522325173014
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http://dx.doi.org/10.1016/j.joco.2018.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276619PMC
December 2018
16 Reads

Serological and PCR-based markers of ocular Chlamydia trachomatis transmission in northern Ghana after elimination of trachoma as a public health problem.

PLoS Negl Trop Dis 2018 12 14;12(12):e0007027. Epub 2018 Dec 14.

Clinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.

Background: Validation of elimination of trachoma as a public health problem is based on clinical indicators, using the WHO simplified grading system. Chlamydia trachomatis (Ct) infection and anti-Ct antibody responses (anti-Pgp3) have both been evaluated as alternative indicators in settings with varying levels of trachoma. There is a need to evaluate the feasibility of using tests for Ct infection and anti-Pgp3 antibodies at scale in a trachoma-endemic country and to establish the added value of the data generated for understanding transmission dynamics in the peri-elimination setting. Read More

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http://dx.plos.org/10.1371/journal.pntd.0007027
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http://dx.doi.org/10.1371/journal.pntd.0007027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310292PMC
December 2018
7 Reads

A case report on complete cure of recurrent primary canaliculitis by 4-snip punctoplasty and canalicular curettage.

Authors:
Min Ho Kim Ho Ra

Medicine (Baltimore) 2018 Dec;97(49):e13508

Department of Ophthalmology and Visual Science, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

Rationale: For the treatment of primary canaliculitis, 1,2,3-snip punctoplasty and canalicular curettage are commonly used; however, a recurrence rate of 6.6% to 22% has been reported. Herein, we describe a case of recurrent primary canaliculitis that was completely cured by 4-snip punctoplasty and canalicular curettage. Read More

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http://dx.doi.org/10.1097/MD.0000000000013508DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310510PMC
December 2018
1 Read

Evaluation of a Single Dose of Azithromycin for Trachoma in Low-Prevalence Communities.

Ophthalmic Epidemiol 2019 02 13;26(1):1-6. Epub 2018 Dec 13.

a Division of Parasitic Diseases and Malaria , Centers for Disease Control and Prevention , Atlanta , GA , USA.

Purpose: Trachoma, caused by repeated ocular infection with Chlamydia trachomatis, is the leading infectious cause of blindness worldwide and is targeted for elimination as a public health problem. We sought to determine whether a one-time azithromycin mass treatment would reduce trachomatous inflammation-follicular (TF) levels below the elimination threshold of 5% in communities with disease prevalence between 5 and 9.9%. Read More

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https://www.tandfonline.com/doi/full/10.1080/09286586.2017.1
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http://dx.doi.org/10.1080/09286586.2017.1293693DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352373PMC
February 2019
13 Reads

The Role of Pneumococcal Virulence Factors in Ocular Infectious Diseases.

Interdiscip Perspect Infect Dis 2018 13;2018:2525173. Epub 2018 Nov 13.

Department of Microbiology and Immunology, University of Mississippi Medical Center, Jackson, MS 39216, USA.

is a gram-positive, facultatively anaerobic pathogen that can cause severe infections such as pneumonia, meningitis, septicemia, and middle ear infections. It is also one of the top pathogens contributing to bacterial keratitis and conjunctivitis. Though two pneumococcal vaccines exist for the prevention of nonocular diseases, they do little to fully prevent ocular infections. Read More

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https://www.hindawi.com/journals/ipid/2018/2525173/
Publisher Site
http://dx.doi.org/10.1155/2018/2525173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257906PMC
November 2018
12 Reads

Adult conjunctivitis secondary to dual infection with and - A case report.

Am J Ophthalmol Case Rep 2019 Mar 14;13:6-8. Epub 2018 Nov 14.

Manchester Royal Eye Hospital, Oxford Road, Manchester, M13 9WL, UK.

Purpose: Although and are the commonest sexually transmitted infections in England, reports of ocular co-infection in the literature are limited. We report such a case which responded well to treatment, and discuss the literature and evidence currently available with regards to management of these cases.

Observations: The patient is a 48-year-old bisexual gentleman who presented to the eye clinic of a UK hospital with redness, discharge and blurred vision in his left eye for one week. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S24519936183017
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http://dx.doi.org/10.1016/j.ajoc.2018.11.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247407PMC
March 2019
14 Reads

Mycobacterium genavense Infection in a Domestic Ferret (Mustela putorius furo).

Top Companion Anim Med 2018 Dec 10;33(4):119-121. Epub 2018 Oct 10.

Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER), 25124 Brescia, Italy.

Mycobacterium genavense infection was diagnosed in an adult ferret with ptosis of the left eye, a proliferative lesion of the conjunctiva of the nictitating membrane, conjunctival swelling, and tumefaction of the periorbital tissues with a watery ocular discharge and the presence of a retrobulbar mass. The diagnosis was based on characteristic cytology of the retrobulbar mass and left mandibular lymph node that revealed granulomatous inflammation. Ziehl-Neelsen staining showed the presence of positive acid-fast bacilli in the cytoplasm of the macrophages. Read More

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http://dx.doi.org/10.1053/j.tcam.2018.10.001DOI Listing
December 2018
1 Read

Neonatal conjunctivitis in the New Zealand Midland region.

N Z Med J 2018 Nov 30;131(1486):9-17. Epub 2018 Nov 30.

Ophthalmologist, Clinical Senior Lecturer, Ophthalmology Department, Department of Medicine, Hauora Tairawhiti, University of Otago, Gisborne.

Aims: To assess the incidence of chlamydial and gonorrhoeal neonatal conjunctivitis (CON and GON), across six district health boards in the greater Midland region of New Zealand.

Methods: All positive nucleic acid amplification test (NAAT) eye swabs for Chlamydia trachomatis and NAAT and bacterial eye swabs for Neisseria gonorrhoeae in infants under one year of age were retrieved from three laboratories from 2013-2016. Incidence density rates were calculated using births information from Statistics New Zealand. Read More

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November 2018
25 Reads

Infantile Acute Conjunctivitis Induced by β-Lactamase-Positive Amoxicillin-Clavulanate-Resistant Strain of Haemophilus influenzae: A Report of Three Cases.

Eye Contact Lens 2018 Nov 22. Epub 2018 Nov 22.

Division of Ophthalmology, Department of Visual Sciences, Nihon University School of Medicine, Tokyo, Japan.

This study is a retrospectively recruited case series. We report three infants with acute conjunctivitis induced by β-lactamase-positive, ampicillin/clavulanic acid-resistant strains of Haemophilus influenzae (BLPACR). Patients with BLPACR-positive cultures were recruited from among 5,107 patients with inflammatory diseases of the ocular surface who underwent examinations, including bacterial culturing of conjunctival sac or corneal scrapings, between 2000 and 2015. Read More

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http://dx.doi.org/10.1097/ICL.0000000000000556DOI Listing
November 2018
3 Reads

Behavioural change interventions for sustained trachoma elimination.

Bull World Health Organ 2018 Oct 10;96(10):723-725. Epub 2018 Sep 10.

Sightsavers, London, England.

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http://dx.doi.org/10.2471/BLT.18.212514DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238993PMC
October 2018
5 Reads

Topical Antibiotics for Clinical and Microbiologic Cure of Bacterial Conjunctivitis.

Acad Emerg Med 2019 Mar 1;26(3):345-346. Epub 2019 Feb 1.

Department of Emergency Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA.

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http://doi.wiley.com/10.1111/acem.13663
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http://dx.doi.org/10.1111/acem.13663DOI Listing
March 2019
9 Reads

Safety of azithromycin in infants under six months of age in Niger: A community randomized trial.

PLoS Negl Trop Dis 2018 11 12;12(11):e0006950. Epub 2018 Nov 12.

Francis I. Proctor Foundation, University of California, San Francisco, San Francisco, California, United States of America.

Background: Mass azithromycin distribution reduces under-5 child mortality. Trachoma control programs currently treat infants aged 6 months and older. Here, we report findings from an infant adverse event survey in 1-5 month olds who received azithromycin as part of a large community-randomized trial in Niger. Read More

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http://dx.plos.org/10.1371/journal.pntd.0006950
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http://dx.doi.org/10.1371/journal.pntd.0006950DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258425PMC
November 2018
21 Reads

Evaluation of content and cost of traditional eye medication in a resource-poor country - Implications for eye care practice and policy.

Niger J Clin Pract 2018 Nov;21(11):1514-1519

Department of Surgery, College of Medicine, University of Nigeria, Nsukka, Enugu State, Nigeria.

Background: Cataract, glaucoma, and conjunctivitis are common causes of ocular morbidity in Nigeria. A major obstacle in reducing the burden of ocular morbidity in rural areas is access to eye care services. Up to 80% of the population in developing countries use traditional medications for their primary healthcare needs because they are accessible, available, and affordable. Read More

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http://dx.doi.org/10.4103/njcp.njcp_201_18DOI Listing
November 2018
10 Reads

A Survey of Current Prophylactic Treatment for Ophthalmia Neonatorum in Croatia and a Review of International Preventive Practices.

Med Sci Monit 2018 Nov 10;24:8042-8047. Epub 2018 Nov 10.

Psychiatric Hospital "Sveti Ivan", Zagreb, Croatia.

BACKGROUND Ophthalmia neonatorum, or neonatal conjunctivitis, is an acute infection that occurs within the first 28 days of life. This aim of this survey was to evaluate the current methods of preventive treatment for ophthalmia neonatorum in maternity hospitals in Croatia. MATERIAL AND METHODS The annual hospital birth rate in Croatia is approximately 40,000. Read More

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https://www.medscimonit.com/abstract/index/idArt/910705
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http://dx.doi.org/10.12659/MSM.910705DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240167PMC
November 2018
6 Reads

Parinaud's Oculoglandular Syndrome in Cat Scratch Disease.

N Engl J Med 2018 Nov;379(18):e31

Universidad de Antioquia, Medellín, Colombia

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http://dx.doi.org/10.1056/NEJMicm1804942DOI Listing
November 2018
5 Reads

Identification of Moraxella lacunata from pulmonary abscesses in three zoo herbivores.

J Vet Med Sci 2018 Dec 29;80(12):1914-1917. Epub 2018 Oct 29.

College of Veterinary Medicine, Kyungpook National University, Daegu 41566, Korea.

Although Moraxella lacunata causes conjunctivitis, keratitis, endocarditis, and otolaryngitis in humans, its infection is rare in animals. We report three cases of asymptomatic pulmonary abscesses caused by M. lacunata in zoo herbivores, including two elks (Cervus canadensis) and a common eland (Taurotragus oryx). Read More

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https://www.jstage.jst.go.jp/article/jvms/advpub/0/advpub_18
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http://dx.doi.org/10.1292/jvms.18-0455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305504PMC
December 2018
10 Reads

[Genetic typing and susceptibility testing of strains from keratitis or conjunctivitis patients].

Zhonghua Yan Ke Za Zhi 2018 Oct;54(10):767-774

Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing 100005, China.

To study the relationship between genetic typing and the antibiotic susceptibility of () isolated from keratitis or conjunctivitis patients. Experimental study. Thirty-four (34) strains of were isolated from 34 cases of keratitis or conjunctivitis. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0412-4081.2018.10.009DOI Listing
October 2018
16 Reads

Antibiotic resistance among bacterial conjunctival pathogens collected in the Antibiotic Resistance Monitoring in Ocular Microorganisms (ARMOR) surveillance study.

PLoS One 2018 18;13(10):e0205814. Epub 2018 Oct 18.

Bausch + Lomb, Rochester, New York, United States of America.

The Antibiotic Resistance Monitoring in Ocular Microorganisms (ARMOR) surveillance study evaluates in vitro antibiotic resistance among Staphylococcus aureus, coagulase-negative staphylococci (CoNS), Streptococcus pneumoniae, Pseudomonas aeruginosa, and Haemophilus influenzae isolates from ocular infections. Here we report resistance rates and trends among conjunctival-sourced ocular isolates collected across the US from 2009 through 2016. A total of 1198 conjunctival isolates (483 S. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0205814PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193682PMC
March 2019
3 Reads

Toxic epidermal necrolysis: the red eye and red herrings in casualty.

BMJ Case Rep 2018 Oct 12;2018. Epub 2018 Oct 12.

Department of Ophthalmology, Queen Elizabeth Hospital Birmingham, Birmingham, Birmingham, UK.

A 38-year-old woman presented to casualty with bilateral red eyes associated with a recent upper respiratory tract infection. This was initially diagnosed as conjunctivitis, however systemic review revealed an erythematous facial and skin rash, mildly swollen lips and mild swallowing difficulties. The patient was referred for an urgent medical assessment, by which time she was found to have erythema affecting 54% of her body surface area and diagnosed with suspected toxic epidermal necrolysis (TEN). Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22586
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http://dx.doi.org/10.1136/bcr-2018-225861DOI Listing
October 2018
14 Reads

Management of giant fornix syndrome with irrigation with povidone-iodine.

BMJ Case Rep 2018 Oct 12;2018. Epub 2018 Oct 12.

Cornea and External Diseases Department, Moorfields Eye Hospital NHS Foundation Trust, London, UK.

Giant fornix syndrome (GFS) was first described as a cause for a relapsing mucopurulent conjunctivitis. Predominantly elderly patients have enlarged superior fornices from superior aponeurosis dehiscence that permits the accumulation of protein coagulum that is colonised by bacteria. Established treatment includes the use of intensive topical antibiotic and corticosteroid. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22555
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http://dx.doi.org/10.1136/bcr-2018-225555DOI Listing
October 2018
16 Reads

Identifying a sufficient core group for trachoma transmission.

PLoS Negl Trop Dis 2018 10 8;12(10):e0006478. Epub 2018 Oct 8.

F.I. Proctor Foundation, University of California San Francisco, San Francisco, CA, United States of America.

Background: In many infectious diseases, a core group of individuals plays a disproportionate role in transmission. If these individuals were effectively prevented from transmitting infection, for example with a perfect vaccine, then the disease would disappear in the remainder of the community. No vaccine has yet proven effective against the ocular strains of chlamydia that cause trachoma. Read More

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http://dx.plos.org/10.1371/journal.pntd.0006478
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http://dx.doi.org/10.1371/journal.pntd.0006478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175502PMC
October 2018
10 Reads

Antibiotic resistance profile in eye infections in a reference centre in Floridablanca, Colombia.

Arch Soc Esp Oftalmol 2019 Jan 27;94(1):4-11. Epub 2018 Sep 27.

Centro Oftalmológico Virgilio Galvis, Floridablanca, Colombia.

Background And Objective: In view of the increasing bacterial resistance to antibiotics, it is necessary to determine it locally in order to serve as a guide in clinical management. The purpose of this study was to characterise the pattern of antibiotic sensitivity in cases of eye infections in a third level ophthalmological institution in Floridablanca (Colombia).

Materials And Methods: An observational cross-sectional study in which an analysis was made of the culture and antibiogram reports of specimens taken from cases of conjunctivitis, infectious keratitis, and endophthalmitis between January 2013 and June 2016. Read More

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http://dx.doi.org/10.1016/j.oftal.2018.07.003DOI Listing
January 2019
2 Reads

Feline Herpesvirus 1 and Mycoplasma spp. Conventional PCR Assay Results From Conjunctival Samples From Cats in Shelters With Suspected Acute Ocular Infections.

Top Companion Anim Med 2018 Jun 29;33(2):45-48. Epub 2018 May 29.

Center for Companion Animal Studies in the Department of Clinical Sciences, Colorado State University, Fort Collins, CO 80524, USA. Electronic address:

Signs of ocular infections like discharge and conjunctivitis occur commonly in cats in shelters and feline herpesvirus 1 (FHV-1), Chlamydia felis, Mycoplasma spp, and feline calicivirus (FCV) are thought to be the most common causes. While molecular assays are available to amplify nucleic acids of each of these agents as single tests or in panels, additional information is needed concerning whether the assay results can be used to predict response to treatment. The objectives of this study were to report results for conventional polymerase chain reaction (PCR) assays that amplify nucleic acids of FHV-1, Mycoplasma spp. Read More

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http://dx.doi.org/10.1053/j.tcam.2018.05.001DOI Listing
June 2018
3 Reads

Feasibility and safety of mass drug coadministration with azithromycin and ivermectin for the control of neglected tropical diseases: a single-arm intervention trial.

Lancet Glob Health 2018 10;6(10):e1132-e1138

The Kirby Institute, University of New South Wales, Sydney, NSW, Australia.

Background: Mass drug administration has made a major contribution to the public health control of several important neglected tropical diseases. For settings with more than one endemic disease, combined mass drug administration has potential practical advantages compared with separate programmes but needs confirmation of feasibility and safety. We undertook a study of mass drug administration in the Solomon Islands for trachoma and scabies control using ivermectin and azithromycin, key drugs in the control of neglected tropical diseases worldwide. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S2214109X183039
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http://dx.doi.org/10.1016/S2214-109X(18)30397-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139784PMC
October 2018
7 Reads

Analysis of the drug therapy of gatifloxacin and levofloxacin in the treatment of acute bacterial conjunctivitis.

Authors:
Jing Xu Jie Feng

Pak J Pharm Sci 2018 Jul;31(4(Special)):1757-1760

Department of Ophthalmology, Jining No.1 People's Hospital, Jining, Shandong, China.

Acute bacterial conjunctivitis is an acute conjunctivitis that is frequently transmitted in summer and autumn. It is a common and frequently occurring disease in ophthalmology clinic. Gatifloxacin is an effective antibacterial drug. Read More

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The trend of resistance to antibiotics for ocular infection of Staphylococcus aureus, coagulase-negative staphylococci, and Corynebacterium compared with 10-years previous: A retrospective observational study.

PLoS One 2018 7;13(9):e0203705. Epub 2018 Sep 7.

Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.

Objective: To retrospectively identify epidemiological trends of infection on the ocular surface and investigate trends of resistance to bacterial antibiotics compared with 10-years previous for Staphylococcus aureus, coagulase-negative staphylococci (CNS), and Corynebacterium in Japan.

Materials And Methods: Bacterial isolate samples were collected from the conjunctival sacs of eyes afflicted with conjunctivitis, keratitis, dacryocystitis, and hordeolum from September 2004 through November 2005 (n = 145 isolates) and September 2014 through November 2015 (n = 195 isolates) at the Baptist Eye Institute, Kyoto, Japan. The prevalence of methicillin-resistant S. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0203705PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128643PMC
February 2019
12 Reads

Conjunctival aerobic bacterial flora in healthy Silesian foals and adult horses in Poland.

BMC Vet Res 2018 Aug 31;14(1):261. Epub 2018 Aug 31.

Department of Internal Medicine and Clinic of Diseases of Horses, Dogs and Cats, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, pl. Grunwaldzki 47, 50-366, Wroclaw, Poland.

Background: Commensal bacterial and fungal flora of the conjunctival sac has been described in horses and other animals. The identification of commensal flora of the conjunctival sac may aid in the diagnosis of ocular inflammatory diseases, such as conjunctivitis or more severe ulcerative keratitis, common in horses. Moreover, damage of ocular protective barriers may lead to an opportunistic infection. Read More

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http://dx.doi.org/10.1186/s12917-018-1598-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119321PMC
August 2018
10 Reads

An impact evaluation of two rounds of mass drug administration on the prevalence of active trachoma: A clustered cross sectional survey.

PLoS One 2018 29;13(8):e0201911. Epub 2018 Aug 29.

Health Education Unit, Education Department, Eugenio María de Hostos Community College, The City University of New York, New York, NY, United States.

Introduction: We investigated the impact of two round of mass drug administration on trachoma prevalence in Plateau and Nasarawa States of Nigeria. The mass drug administration was conducted as a component of the SAFE Strategy, a combination of interventions recommended for the global elimination of blinding trachoma.

Methods: The study consisted of a two-stage cross-sectional clustered sample survey in which 3990 people from 793 households were screened for clinical signs of trachoma. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0201911PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114510PMC
February 2019
22 Reads

Management of Bacterial Conjunctivitis in Children-Preferred Practice Pattern in Northern Greece.

Eye Contact Lens 2018 09;44 Suppl 1:S373-S374

Second Department of Ophthalmology (A.M., E.P., V.T., and E.M.), Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece; Department of Hygiene and Epidemiology (S.K. and A.-B.H.), Aristotle University of Thessaloniki, Greece; and First Department of Ophthalmology (N.Z.), Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.

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http://dx.doi.org/10.1097/ICL.0000000000000452DOI Listing
September 2018
21 Reads

A Longitudinal Analysis of Chlamydial Infection and Trachomatous Inflammation Following Mass Azithromycin Distribution.

Ophthalmic Epidemiol 2019 02 28;26(1):19-26. Epub 2018 Aug 28.

a Francis I. Proctor Foundation , University of California , San Francisco , CA , USA.

Background: Mass azithromycin distributions are effective for clearing ocular strains of Chlamydia trachomatis, yet infection frequently returns in areas with hyperendemic trachoma. A better understanding of the factors associated with chlamydial reinfection could be helpful to plan trachoma elimination strategies.

Methods: This was a prospective cohort study conducted in a trachoma-hyperendemic region of Ethiopia in 2003. Read More

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http://dx.doi.org/10.1080/09286586.2018.1512635DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344262PMC
February 2019
9 Reads

The challenges of treating tracheobronchitis in a laryngectomee due to nontypeable Haemophilus influenzae: a case report.

Authors:
Itzhak Brook

J Med Case Rep 2018 Aug 20;12(1):242. Epub 2018 Aug 20.

Department of Pediatrics and Medicine, Georgetown University School of Medicine, Washington DC, 20007, USA.

Background: Laryngectomees run the risk of developing severe respiratory tract infections especially during the winter and when they do not wear a stoma cover. A case of severe tracheobronchitis in a laryngectomee is presented that illustrates the risks and difficulties encountered in managing this infection in a neck breather.

Case Presentation: A 76-year-old Caucasian man, a laryngectomee, presented with bacterial tracheobronchitis and conjunctivitis due to beta-lactamase-producing nontypeable Haemophilus influenzae. Read More

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http://dx.doi.org/10.1186/s13256-018-1764-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100715PMC
August 2018
4 Reads

Ocular bacterial infections and antibiotic resistance patterns in patients attending Gondar Teaching Hospital, Northwest Ethiopia.

BMC Res Notes 2018 Aug 17;11(1):597. Epub 2018 Aug 17.

Department of Ophthalmology, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Objectives: Empirical selections of antimicrobial therapy based on clinical observations are common clinical practices in Ethiopia. This study identified common external ocular infections and determined antibiotic susceptibility testing in northwest Ethiopia.

Results: Among 210 patients studied, conjunctivitis 32. Read More

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http://dx.doi.org/10.1186/s13104-018-3705-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098601PMC
August 2018
7 Reads

Mass azithromycin distribution for hyperendemic trachoma following a cluster-randomized trial: A continuation study of randomly reassigned subclusters (TANA II).

PLoS Med 2018 08 14;15(8):e1002633. Epub 2018 Aug 14.

Francis I. Proctor Foundation, University of California, San Francisco, San Francisco, California, United States of America.

Background: The World Health Organization recommends annual mass azithromycin administration in communities with at least 10% prevalence of trachomatous inflammation-follicular (TF) in children, with further treatment depending on reassessment after 3-5 years. However, the effect of stopping mass azithromycin distribution after multiple rounds of treatment is not well understood. Here, we report the results of a cluster-randomized trial where communities that had received 4 years of treatments were then randomized to continuation or discontinuation of treatment. Read More

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http://dx.doi.org/10.1371/journal.pmed.1002633DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091918PMC
August 2018
27 Reads

Infectious Disease in Contact Sports.

Sports Health 2019 Jan/Feb;11(1):47-58. Epub 2018 Aug 14.

University of Minnesota, Minneapolis, Minnesota.

Context:: Infections are common in contact sports. This review aims to describe the epidemiology, presenting signs and symptoms, treatment guidelines, and regulations for several common infections seen in contact sport athletes. The conditions discussed include bacterial skin infections, herpes simplex virus, molluscum contagiosum, common warts, tinea, scabies, head lice, conjunctivitis, human immunodeficiency virus, hepatitis C virus, and vaccine-preventable illnesses. Read More

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http://dx.doi.org/10.1177/1941738118789954DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299350PMC
February 2019
13 Reads