23,485 results match your criteria Conjunctivitis


Comparison of the safety and efficacy of topical Tacrolimus (0.03%) versus dexamethasone (0.05%) for subepithelial infiltrates after adenoviral conjunctivitis.

Indian J Ophthalmol 2019 May;67(5):594-598

Department of Ophthalmology, Laser Eye Clinic, Noida, UP, India.

Purpose: To compare the safety and efficacy of tacrolimus 0.03% ointment with dexamethasone 0.05% ointment for subepithelial infiltrates (SEIs) following adenoviral keratoconjunctivitis (AK). Read More

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http://dx.doi.org/10.4103/ijo.IJO_1352_18DOI Listing

Radiation-induced optic neuropathy after stereotactic and image guided intensity-modulated radiation therapy (IMRT).

Radiother Oncol 2019 May 18;134:166-177. Epub 2019 Feb 18.

Department of Radiation Oncology, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University, Germany; Heinrich-Lanz-Center for Digital Medicine, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany. Electronic address:

Background/purpose: To quantify the risk of radiation-induced optic neuropathy (RION) after stereotactic/image-guided positioning and intensity-modulated radiotherapy (IMRT) with ≥50 Gy to the anterior visual pathway (AVP).

Methods: Patients irradiated with ≥50 Gy to the AVP using stereotactic/image-guided positioning between 2002 and 2011 in Mannheim were identified. Detailed dosimetric data were collected and patients or family members were retrospectively asked to rate visual acuity and visual disorders. Read More

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http://dx.doi.org/10.1016/j.radonc.2019.02.003DOI Listing

Lassa Virus Targeting of Anterior Uvea and Endothelium of Cornea and Conjunctiva in Eye of Guinea Pig Model.

Emerg Infect Dis 2019 May;25(5):865-874

Lassa virus (LASV), a hemorrhagic fever virus endemic to West Africa, causes conjunctivitis in patients with acute disease. To examine ocular manifestations of LASV, we histologically examined eyes from infected guinea pigs. In fatal disease, LASV immunostaining was most prominent in the anterior uvea, especially in the filtration angle, ciliary body, and iris and in and around vessels in the bulbar conjunctiva and peripheral cornea, where it co-localized with an endothelial marker (platelet endothelial cell adhesion molecule). Read More

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http://wwwnc.cdc.gov/eid/article/25/5/18-1254_article.htm
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http://dx.doi.org/10.3201/eid2505.181254DOI Listing
May 2019
1 Read

Neonatal Conjunctivitis Caused by Neisseria meningitidis US Urethritis Clade, New York, USA, August 2017.

Emerg Infect Dis 2019 May;25(5):972-975

We characterized a case of neonatal conjunctivitis in New York, USA, caused by Neisseria meningitidis by using whole-genome sequencing. The case was a rare occurrence, and the isolate obtained belonged to an emerging clade (N. meningitidis US nongroupable urethritis) associated with an increase in cases of urethritis since 2015. Read More

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http://dx.doi.org/10.3201/eid2505.181631DOI Listing

Multimorbidity in Asthma, Allergic Conditions and COPD Increase Disease Severity, Drug Use and Costs: The Finnish Pharmacy Survey.

Int Arch Allergy Immunol 2019 Apr 18:1-8. Epub 2019 Apr 18.

Skin and Allergy Hospital, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.

Background: Asthma, allergic conditions, and COPD overlap, but the effect of them and their combinations on disease severity, need for drugs, use of healthcare, and costs is poorly known.

Objective: To study how different allergic diseases co-occur in asthma and allergy patients and evaluate the use of medication well as drug and healthcare costs.

Methods: Nationwide Allergy Barometer Survey was carried out in the Finnish pharmacies during 1 week in September 2016. Read More

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http://dx.doi.org/10.1159/000498861DOI Listing
April 2019
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Evaluation of the schistosomicidal, antioxidant and anti-inflammatory activities of the ethyl acetate fraction from Ozoroa pulcherrima Schweinf. Roots on Schistosoma mansoni-induced liver pathology in mice and its phytochemical characterization.

J Ethnopharmacol 2019 Apr 15;238:111883. Epub 2019 Apr 15.

Laboratory of Biology, Department of Animal Biology and Physiology, Faculty of Science, University of Yaoundé I, P.O. Box 812, Yaoundé, Cameroon; Centre for Schistosomiasis and Parasitology, P.O. Box 7244, Yaoundé, Cameroon. Electronic address:

Ethnopharmacological Relevance: Ozoroa pulcherrima Schweinf. (syn.: Heeria pulcherrrima Schweinf. Read More

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http://dx.doi.org/10.1016/j.jep.2019.111883DOI Listing
April 2019
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Prevalence of vernal keratoconjunctivitis and its associated factors among children in Gambella town, southwest Ethiopia, June 2018.

PLoS One 2019 18;14(4):e0215528. Epub 2019 Apr 18.

Department of Optometry, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Introduction: Vernal keratoconjunctivitis is a chronic bilateral severe form of allergic conjunctivitis which affects normal activities in school/work. It is a severe form of allergies in warm and dry tropical and sub-tropical countries. Its prevalence in Ethiopia ranges from 5. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215528PLOS
April 2019
2 Reads

A curious association of chronic homeopathic arsenic ingestion with nonspecific symptoms in a Swiss teenager.

Authors:
Sergio U Dani

Swiss Med Wkly 2019 Apr 17;149:w20071. Epub 2019 Apr 17.

Medawar Institute for Medical and Environmental Research, Acangau Foundation, Paracatu, MG, Brazil, and PizolCare Praxis Sargans, Switzerland.

Arsenic is a toxicant that has no dose threshold below which exposures are not harmful. Here I report a curious association of chronic homeopathic arsenic ingestion with nonspecific symptoms in a Swiss teenager. For about 4 years she had taken globules of a freely purchasable homeopathic remedy containing inorganic arsenic (iAs), infinitesimally diluted to D6 (average arsenic content per single globule: 0. Read More

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https://doi.emh.ch/smw.2019.20071
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http://dx.doi.org/10.4414/smw.2019.20071DOI Listing
April 2019
2 Reads

Learning About Dupilumab-Associated Conjunctivitis.

JAMA Dermatol 2019 Apr 17. Epub 2019 Apr 17.

University of Arizona Department of Medicine, Division of Dermatology, Tucson.

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http://dx.doi.org/10.1001/jamadermatol.2018.5951DOI Listing

Learning About Dupilumab-Associated Conjunctivitis-Reply.

JAMA Dermatol 2019 Apr 17. Epub 2019 Apr 17.

Department of Dermatology, Feinberg School of Medicine, Northwestern, University, Chicago, Illinois.

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http://archderm.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamadermatol.2019.0209DOI Listing
April 2019
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Prophylactic protocol for dental care in ligneous gingivitis due to severe plasminogen deficiency: Case report and review of literature.

Haemophilia 2019 Apr 17. Epub 2019 Apr 17.

Clinical Medicine I, Department of Medicine, University of Padua, Padua, Italy.

Introduction: Severe plasminogen (PLG) deficiency causes ligneous conjunctivitis, a rare disease characterized by the growth of fibrin-rich pseudomembranes on mucosal surfaces; gums involvement leads to ligneous gingivitis (LG). Specific therapy for LG is not available yet. We report a prophylactic treatment with enoxaparin and fresh frozen plasma (FFP) for invasive dental procedures in a patient with LG, and a review of literature on LG treatment. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/hae.13745
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http://dx.doi.org/10.1111/hae.13745DOI Listing
April 2019
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Preparation and Evaluation of Topically Applied Azithromycin Based on Sodium Hyaluronate in Treatment of Conjunctivitis.

Pharmaceutics 2019 Apr 15;11(4). Epub 2019 Apr 15.

Department of Pharmaceutics, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, China.

Azithromycin (AZI) eye drops containing sodium hyaluronate (SH) were developed to improve the bioavailability of AZI. Interaction between AZI and SH in the AZI-SH formulation was investigated by differential scanning calorimetry, X-ray diffraction, and ¹H-nuclear magnetic resonance spectroscopy analyses. Moreover, advantages of using SH as an excipient were investigated by comparing physiological properties and pharmacokinetic behaviors of SH-containing AZI eye drops with that of hydroxypropyl methylcellulose (HPMC)-containing formulation. Read More

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http://dx.doi.org/10.3390/pharmaceutics11040183DOI Listing
April 2019
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Two Soft Contact Lenses Retained in the Superior Fornix for 15 Years in a Patient With Unique Orbital Anatomy.

Eye Contact Lens 2019 Apr 9. Epub 2019 Apr 9.

Michigan State University College of Osteopathic Medicine (C.H., J.S.), East Lansing, MI; and Holicki Eye Center and Optical (J.H.), Coldwater, MI.

A 70-year-old white woman presented to her ophthalmologist with bacterial conjunctivitis resistant to treatment. The relationship between the patient's globe and superior orbital rim prompted high clinical suspicion of an occult foreign body as the cause. The following article describes the office visits preceding the discovery of two adhered soft contact lenses lodged in the superior fornix of the right eye that had been hidden for 15 years. Read More

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http://dx.doi.org/10.1097/ICL.0000000000000609DOI Listing

Google searches and detection of conjunctivitis epidemics worldwide.

Ophthalmology 2019 Apr 11. Epub 2019 Apr 11.

F.I. Proctor Foundation, University of California San Francisco, San Francisco, CA, USA; Department of Ophthalmology, University of California San Francisco, San Francisco, CA, USA; Department of Epidemiology and Biostatistics, Global Health Sciences, University of California San Francisco, San Francisco, CA, USA. Electronic address:

Purpose: and Objective: Epidemic and seasonal infectious conjunctivitis outbreaks can adversely impact education, workforce and economy. Yet conjunctivitis is typically not a reportable disease, potentially delaying mitigating intervention. Our study objective was to determine if conjunctivitis epidemics could be identified using Google Trends search data. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01616420183229
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http://dx.doi.org/10.1016/j.ophtha.2019.04.008DOI Listing
April 2019
2 Reads
6.135 Impact Factor

Colonization of therapeutic contact lens by dematiaceous fungi.

Cont Lens Anterior Eye 2019 Apr 10. Epub 2019 Apr 10.

Department of Cornea and Refractive Services, Aravind Eye Hospital 1, Anna Nagar, Madurai, 625020, Tamil Nadu, India.

Purpose: To report 2 patients with colonization of therapeutic contact lens with dematiaceous fungi.

Methods: Case report.

Results: The first patient had a retained soft contact lens on an opaque cornea for 4 years with brownish black multiple colonies on the soft contact lens and culture grew Bipolaris spp. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13670484183104
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http://dx.doi.org/10.1016/j.clae.2019.04.008DOI Listing
April 2019
1 Read

Allergic rhinitis increases the risk of incident panic disorder among young individuals: A nationwide population-based cohort study in Taiwan.

J Affect Disord 2019 Apr 9;252:60-67. Epub 2019 Apr 9.

Tsaotun Psychiatric Center, Ministry of Health and Welfare, 542 No.161, Yu-Pin Rd, Caotun Township, Nantou, Taiwan, R.O.C.. Electronic address:

Background: Studies have reported an association between allergy and panic disorder. However, few studies have explored the relationship between allergic rhinitis and panic disorder. Previous studies were limited by cross-sectional study designs, self-reported symptoms, absence of matched controls, and lack of consideration of the influence of steroid and comorbidities. Read More

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http://dx.doi.org/10.1016/j.jad.2019.04.037DOI Listing
April 2019
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Outcome of External Dacryocystorhinostomy and Monocanalicular Intubation in Patients with Total Obstruction of One Canalicus.

Korean J Ophthalmol 2019 Apr;33(2):138-141

Department of Ophthalmology, Medipol University Medical Faculty, Istanbul, Turkey.

Purpose: We sought to evaluate the outcomes of external dacryocystorhinostomy (DCR) and mono-canalicular intubation in patients with total obstruction of one canalicus.

Methods: Sixteen eyes of 16 patients with nasolacrimal duct obstruction and a single canaliculus obstruction who had undergone external DCR and monocanalicular intubation of the intact canaliculus were retrospectively included in the present study. The monocanalicular tube (Mini Monoka) was left in place for at least two months. Read More

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http://dx.doi.org/10.3341/kjo.2018.0077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462472PMC

Retrospective analysis of infectious laryngotracheitis in backyard chicken flocks in California, 2007-2017, and determination of strain origin by partial ICP4 sequencing.

J Vet Diagn Invest 2019 Apr 11:1040638719843574. Epub 2019 Apr 11.

California Animal Health & Food Safety Laboratory System, Turlock Branch (Blakey, Stoute), University of California-Davis, Davis, CA.

Infectious laryngotracheitis (ILT) can cause severe losses in backyard flocks (BYFs) and commercial poultry. The prevalence of ILT, the circulating strains of ILT virus (ILTV) in BYFs, and the correlation of disease in BYF and commercial operations, is largely unknown. Of 8,656 BYF submissions, 88 cases of ILT were diagnosed at the California Animal Health and Food Safety Laboratory System in 2007-2017. Read More

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http://dx.doi.org/10.1177/1040638719843574DOI Listing

Benzalkonium Chloride Demonstrates Concentration-Dependent Antiviral Activity Against Adenovirus In Vitro.

J Ocul Pharmacol Ther 2019 Apr 10. Epub 2019 Apr 10.

The Charles T. Campbell Ophthalmic Microbiology Laboratory, UPMC Eye Center, Ophthalmology and Visual Sciences Research Center, Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

Purpose: Adenoviral conjunctivitis is the most common cause of conjunctivitis worldwide with no approved antiviral treatment. Benzalkonium chloride (BAK) is a common preservative in ophthalmic medications and is the active ingredient in some skin disinfectants and hand sanitizers. BAK is known to be effective in killing bacteria and enveloped viruses; however, its activity against ocular types of nonenveloped adenoviruses (Ads) is unknown. Read More

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https://www.liebertpub.com/doi/10.1089/jop.2018.0145
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http://dx.doi.org/10.1089/jop.2018.0145DOI Listing
April 2019
2 Reads

Spectrum of the neurologic manifestations in childhood-onset cryopyrin-associated periodic syndrome.

Eur J Paediatr Neurol 2019 Mar 28. Epub 2019 Mar 28.

Department of Pediatric Neurology, Istanbul University-Cerrahpasa, Cerrahpasa Medical School, Istanbul, Turkey.

Objective: Neurologic complications of chronic infantile neurologic, cutaneous and articular syndrome (CINCA) are well-known, whereas there are scarce data regarding neurologic features of milder cryopyrin-associated periodic syndrome (CAPS) phenotypes. We aimed to review the neurologic features in detail and summarize the other CAPS-related manifestations in 12 children.

Methods: All children with CAPS that have been followed-up from pediatric rheumatology outpatient clinic, were enrolled to the study. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10903798183056
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http://dx.doi.org/10.1016/j.ejpn.2019.03.006DOI Listing
March 2019
2 Reads

Tear Inflammatory Molecules in Contact Lens Wearers: A Literature Review.

Curr Med Chem 2019 Apr 9. Epub 2019 Apr 9.

Institute of Applied Ophthalmobiology (IOBA)-University of Valladolid, Valladolid. Spain.

Background: numerous studies have analysed the effect of using different contact lenses (CLs) or care solutions, and suffering discomfort or diseases associated with CL wear on the inflammatory mediator release into the tears.

Objective: to summarize the published data on tear inflammatory molecules related to CL use.

Method: a PubMed-NCBI search has been conducted and those publications which carried out original investigations including the analysis of tear inflammatory mediators in CL wearers were selected. Read More

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http://dx.doi.org/10.2174/0929867326666190409152921DOI Listing
April 2019
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A randomized controlled trial of povidone-iodine/dexamethasone ophthalmic suspension for acute viral conjunctivitis.

Clin Ophthalmol 2019 21;13:535-544. Epub 2019 Mar 21.

Ophthalmics, Shire, A Takeda Company, Lexington, MA, USA.

Purpose: To evaluate the clinical safety and efficacy of povidone-iodine (PVP-I) 0.6%/dexamethasone (DEX) 0.1% ophthalmic suspension vs vehicle in patients with clinically suspected acute viral conjunctivitis. Read More

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http://dx.doi.org/10.2147/OPTH.S191275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433103PMC
March 2019
1 Read

Treatment of atopic dermatitis with dupilumab: experience from a tertiary referral center.

J Eur Acad Dermatol Venereol 2019 Apr 8. Epub 2019 Apr 8.

Department of Dermato-venereology, Bispebjerg Hospital, University of Copenhagen, Denmark.

Background: Management of moderate-to severe atopic dermatitis (AD) frequently requires treatment with systemic therapies. Dupilumab is the first biological agent approved for treatment of moderate-to severe AD. Although promising results have appeared in clinical trials, real-life data on efficacy and safety are lacking. Read More

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http://dx.doi.org/10.1111/jdv.15609DOI Listing
April 2019
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Late Treatment and Recurrence of Kawasaki Disease in a Moroccan Infant.

Case Rep Pediatr 2019 5;2019:3904932. Epub 2019 Mar 5.

Pediatric A Department, Mother-Child Pole, Mohammed VI University Hospital, Marrakesh, Morocco.

Introduction: While the diagnosis of typical form of Kawasaki disease (KD) is obvious, this multifaceted disease continues to surprise us. We report the case of a recurrent Kawasaki disease in an infant.

Case: At the age of 13 months, the infant was diagnosed with complete Kawasaki disease; he presented with prolonged fever, bilateral conjunctivitis, enanthem, exanthema, edema of the lower limb, peeling, and biological inflammatory syndrome. Read More

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http://dx.doi.org/10.1155/2019/3904932DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425317PMC
March 2019
2 Reads

Peste Des Petits Ruminants (PPR) in Dromedary Camels and Small Ruminants in Mandera and Wajir Counties of Kenya.

Adv Virol 2019 4;2019:4028720. Epub 2019 Mar 4.

Department of Veterinary Pathology, Microbiology and Parasitology, University of Nairobi, P.O. Box 29053, Kangemi, Kenya.

A study was conducted to determine the presence of Peste des petits ruminants (PPR) in camel population kept together with small ruminants in Isiolo, Mandera, Marsabit, and Wajir counties of Kenya. This was done in the wake of a disease with unknown etiology "" camels in the horn of Africa. Thirty-eight (38) samples, 12, 8, 15, and 3 samples, were collected from Mandera, Wajir, Isiolo, and Marsabit, respectively, from 25 camels, 7 goats, and 4 sheep. Read More

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http://dx.doi.org/10.1155/2019/4028720DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425320PMC
March 2019
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Unbiased Pathogen Detection and Host Gene Profiling for Conjunctivitis.

Ophthalmology 2019 Apr 3. Epub 2019 Apr 3.

Francis I. Proctor Foundation, University of California San Francisco, San Francisco, CA, USA; Department of Ophthalmology, University of California, San Francisco, CA, USA. Electronic address:

Purpose: The etiology of conjunctivitis is often misdiagnosed. An ideal diagnostic test would identify all possible infectious causes. In this study, we apply unbiased metagenomic RNA deep sequencing (MDS) to identify pathogens causing conjunctivitis. Read More

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http://dx.doi.org/10.1016/j.ophtha.2019.03.039DOI Listing
April 2019
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Mobile technology offers novel insights on control and treatment of allergic rhinitis. The MASK study.

J Allergy Clin Immunol 2019 Apr 2. Epub 2019 Apr 2.

MACVIA-France, Fondation partenariale FMC VIA-LR, Montpellier, France; Epidemiology of Allergic and Respiratory Diseases, Department Institute Pierre Louis of Epidemiology and Public Health, INSERM and UPMC Sorbonne Université, Medical School Saint Antoine, Paris, France; INSERM U 1168, VIMA : Ageing and chronic diseases Epidemiological and public health approaches, Villejuif, Université Versailles St-Quentin-en-Yvelines, UMR-S 1168, Montigny le Bretonneux, France and Euforea, Brussels, Belgium. Electronic address:

Background: Mobile health may be used to generate innovative insights into optimizing treatment to improve allergic rhinitis control.

Objectives: A cross-sectional real world observational study was undertaken in 22 countries to complement a pilot study and bring novel information on medication use, disease control and work productivity in everyday life of patients with allergic rhinitis.

Methods: A mobile phone app (Allergy Diary, freely available Google Play and Apple stores) was used to collect data of daily visual analogue scales (VAS) for (i) overall allergic symptoms, (ii) nasal, ocular and asthma symptoms, (iii) work, as well as (iv) medication use using a treatment scroll list including all allergy medications (prescribed and over-the-counter (OTC)) customized for 22 countries. Read More

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http://dx.doi.org/10.1016/j.jaci.2019.01.053DOI Listing
April 2019
8 Reads
11.476 Impact Factor

Topical Tacrolimus for Chronic Allergic Conjunctival Disease with and without Atopic Dermatitis.

Curr Eye Res 2019 Apr 5:1-10. Epub 2019 Apr 5.

k Okamoto Eye Clinic , Ehime , Japan.

Purpose/Aim: This study evaluated the efficacy of topical 0.1% tacrolimus ophthalmic suspension for treating chronic allergic conjunctival disease with and without atopic dermatitis.

Materials And Methods: This study was conducted as a prospective observational post-market survey. Read More

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http://dx.doi.org/10.1080/02713683.2019.1600197DOI Listing
April 2019
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[Ocular symptoms associated with dupilumab in atopic dermatitis].

Ned Tijdschr Geneeskd 2019 Mar 21;163. Epub 2019 Mar 21.

UMC Groningen, afd. Dermatologie.

Background: Dupilumab, the first registered biological for the treatment of atopic dermatitis, frequently causes adverse ocular events. These often take the form of mild conjunctivitis or blepharoconjunctivitis, however, more serious adverse ocular events have also been reported, including limbal stem cell insufficiency.

Case Description: A 56-year-old man was treated with dupilumab for severe atopic dermatitis. Read More

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March 2019
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Shortened up-dosing with sublingual immunotherapy drops containing tree allergens is well tolerated and elicits dose-dependent clinical effects during the first pollen season.

World Allergy Organ J 2019 8;12(2):100012. Epub 2019 Mar 8.

Bencard Allergie GmbH, Munich, Germany.

Background: This study compared a rapid home-based up-dosing schedule for sublingual immunotherapy (SLIT) drops containing tree pollen allergens with two previously established schedules. Furthermore, the clinical effect of the SLIT was investigated with respect to patients' first pollen season under treatment.

Methods: In this open-label, prospective, patient-preference, non-interventional study, local and systemic reactions were compared between three up-dosing groups using a SLIT formulation containing birch, alder, and hazel pollen extracts (ORALVAC Compact ). Read More

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http://dx.doi.org/10.1016/j.waojou.2019.100012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439405PMC
March 2019
1 Read

[Tacrolimus ointment in the management of atopic keratoconjunctivitis].

J Fr Ophtalmol 2019 Mar 29. Epub 2019 Mar 29.

Service d'ophtalmologie, CHU de Rouen, 1, rue de Germont, 76000 Rouen, France. Electronic address:

Introduction: Atopic keratoconjunctivitis is associated with eyelid eczema. It may require the use of local corticosteroids which if prolonged can be a source of ocular complications. Tacrolimus is an immunosuppressant used in cutaneous application in atopic dermatitis. Read More

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http://dx.doi.org/10.1016/j.jfo.2018.07.018DOI Listing
March 2019
2 Reads

Evolving patterns of reactive arthritis.

Clin Rheumatol 2019 Mar 27. Epub 2019 Mar 27.

Department of Medicine, Schulich School of Medicine & Dentistry, Western University, London, Canada.

Objective: To characterize rheumatologists' perspectives on evolving trends of reactive arthritis (ReA).

Methods: After ethics approval, 548 members of the Canadian Rheumatology Association were surveyed with 37 questions covering their demographic information, subspecialty, level of experience, practice setting and opinions on prevalence, treatment, and causes of ReA. Results were analyzed with descriptive statistics. Read More

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http://dx.doi.org/10.1007/s10067-019-04522-4DOI Listing
March 2019
1 Read

Brimonidine-induced unilateral ocular lichen planus: a case report.

Arq Bras Oftalmol 2019 Mar 25. Epub 2019 Mar 25.

Servicio de Oftalmología, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Madrid, Spain.

This report was written to describe a case of unilateral brimonidine-induced conjunctival lichen planus. Because the ophthalmic examination indicated chronic conjunctivitis or drug-induced pseudopemphigoid, the patient underwent thorough ophthalmic and systemic examinations, as well as conjunctival biopsy and direct immunofluorescence studies. A 71-year-old woman with unilateral left eye findings of chronic conjunctivitis was referred to our Ophthalmology Department. Read More

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http://dx.doi.org/10.5935/0004-2749.20190047DOI Listing

Infective conjunctivitis progressing to posterior scleritis.

Clin Exp Ophthalmol 2019 Mar 26. Epub 2019 Mar 26.

Sydney Eye Hospital, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1111/ceo.13503DOI Listing

Rosácea infantil.

Bol Med Hosp Infant Mex 2019 ;76(2):95-99

División de Dermatología y Micología, Hospital General Dr. Manuel Gea González, Ciudad de México. México.

Background: Rosacea is a chronic inflammatory skin condition that usually occurs in adults and rarely has been reported in children, although both subtypes share the same clinical characteristics.

Case Report: A 10-year-old female presented dermostosis on the face, affecting cheeks and nose, characterized by erythema, papules, pustules, scars of two years of evolution, as well as bilateral conjunctivitis, blepharitis and corneal opacity. She referred recurrent exacerbations and partial remission of cutaneous lesions and ocular symptoms related to sun exposure. Read More

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http://dx.doi.org/10.24875/BMHIM.18000032DOI Listing
January 2019
1 Read

Effect of incremental feature enrichment on healthcare text classification system: A machine learning paradigm.

Comput Methods Programs Biomed 2019 Apr 1;172:35-51. Epub 2019 Feb 1.

Advanced Knowledge Engineering Center, Global Biomedical Technologies, Inc., Roseville, CA, USA. Electronic address:

Background And Objective: Healthcare tweets are particularly challenging due to its sparse layout and its limited character size. Compared to previous method based on "bag of words" (BOW) model, this study uniquely identifies the enrichment protocol and learns how semantically different aspects of feature selection such as BOW (feature F0), term frequency inverse document frequency (TF-IDF, feature F1), and latent semantic indexing (LSI, feature F2) when applied sequentially with classifier improves the overall performance.

Methods: To study this enrichment concept, our ML model is tested on two kinds of diverse data sets: (i) D1: Disease data with conjunctivitis, diarrhea, stomach ache, cough and nausea related tweets, and (ii) D2: WebKB4 dataset, while adapting three kind of classifiers (a) C1: support vector machine with radial basis function (SVMR), (b) C2: Multi-layer perceptron (MLP) and (c) C3: Random Forest (RF). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01692607183181
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http://dx.doi.org/10.1016/j.cmpb.2019.01.011DOI Listing
April 2019
4 Reads

Food allergy in adults: substantial variation in prevalence and causative foods across Europe.

J Allergy Clin Immunol Pract 2019 Mar 18. Epub 2019 Mar 18.

Department of Dermatology and Allergology, University Medical Center Utrecht, Utrecht, The Netherlands.

Background: The EuroPrevall study showed that prevalence of self-reported food allergy (FA) in adults across Europe ranged from 2-37% for any food and 1-19% for 24 selected foods.

Objective: To determine prevalence of probable FA (symptoms plus sIgE-sensitisation) and challenge-confirmed FA in European adults, along with symptoms and causative foods.

Methods: In phase I of the EuroPrevall project, a screening questionnaire was sent to a random sample of the general adult population in eight European centres. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22132198193026
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http://dx.doi.org/10.1016/j.jaip.2019.02.044DOI Listing
March 2019
3 Reads

A review of 4652 exposures to liquid laundry detergent capsules reported to the United Kingdom National Poisons Information Service 2008-2018.

Clin Toxicol (Phila) 2019 Mar 20:1-8. Epub 2019 Mar 20.

a NPIS (Birmingham Unit) , City Hospital , Birmingham , UK.

Introduction: Liquid laundry detergent capsules contain concentrated liquid laundry detergent in a water-soluble polyvinyl alcohol membrane.

Objective: To review 4652 exposures reported to the United Kingdom National Poisons Information Service (NPIS) and to assess the impact of regulatory changes on potential toxicity.

Methods: Telephone enquiries to the NPIS and returned questionnaires for these products were analyzed for the period January 2008 to December 2018. Read More

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https://www.tandfonline.com/doi/full/10.1080/15563650.2019.1
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http://dx.doi.org/10.1080/15563650.2019.1590586DOI Listing
March 2019
8 Reads

Severe mycotic keratoconjunctivitis caused by sp. in an immunocompetent child successfully treated with intravenous voriconazole and keratoplasty: case report and short review of the literature.

Ther Adv Infect Dis 2019 Jan-Dec;6:2049936118811213. Epub 2018 Nov 12.

University of Texas Rio Grande Valley, Rio Grande Valley, TX, USA.

Background: Pediatric mycotic infections in the eye are uncommon. However, ophthalmic infections by several fungal species have been described in immunocompetent subjects. Mycotic keratitis with or without conjunctivitis (MK) may account for more than 50% of all cases, particularly in tropical and sub-tropical areas. Read More

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http://dx.doi.org/10.1177/2049936118811213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416680PMC
November 2018

Stromal Fibroblasts Drive Host Inflammatory Responses That Are Dependent on Chlamydia trachomatis Strain Type and Likely Influence Disease Outcomes.

MBio 2019 03 19;10(2). Epub 2019 Mar 19.

Center for Immunobiology and Vaccine Development, UCSF Benioff Children's Hospital Oakland Research Institute, Oakland, California, USA

ocular strains cause a blinding disease known as trachoma. These strains rarely cause urogenital infections and are not found in the upper genital tract or rectum. Urogenital strains are responsible for a self-limited conjunctivitis and the sequelae of infertility, ectopic pregnancy, and hemorrhagic proctitis. Read More

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http://dx.doi.org/10.1128/mBio.00225-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426598PMC
March 2019
1 Read

Comment on article: “Zika, afebrile disease?”

Rev Med Inst Mex Seguro Soc 2019 Mar 15;56(6):516. Epub 2019 Mar 15.

Sanitation 1 Medical Academic Center. Bangkok, Thailand

We read with great interest the publication entitled “Zika, afebrile disease?” from del Carpio-Orantes and González-Clemente,1 who mentioned that afebrile illness might be seen in Zika virus infection and concluded that “…we point out that symptoms such as nonpurulent conjunctivitis or rash could be reliable criteria in the absence of fever for the probable diagnosis of Zika, which invariably requires serological confirmation, even though the latter is not always available.” We would like to share ideas and experience on this issue. In our setting, Indochina, the Zika virus infection is also endemic. Read More

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Management of ocular allergy.

Allergy 2019 Mar 19. Epub 2019 Mar 19.

CHU Estaing, Unité d'Allergologie de l'Enfant CHU Estaing 63003 Clermont-Ferrand Cedex1, France.

The treatment and management of ocular allergy (OA) remains a major concern for different specialties, including allergists, ophthalmologists, primary care physicians, rhinologists, pediatricians, dermatologists, clinical immunologists and pharmacists. We performed a systematic review of all relevant publications in Medline, SCOPUS and WebScience including systematic reviews and meta-analysis. Publications were considered relevant if they addressed treatments, or management strategies of OA. Read More

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http://dx.doi.org/10.1111/all.13786DOI Listing
March 2019
6 Reads

Post-traumatic endophthalmitis caused by .

JMM Case Rep 2019 Feb 20;6(2):e005175. Epub 2019 Feb 20.

Departament of Microbiology, University Hospital Marqués de Valdecilla - IDIVAL, Santander, Spain.

Introduction: complex has been associated with infections in both immunocompetent and immunocompromised patients. Infection can be localized or disseminated, affecting skin and soft tissues, the respiratory system, bones and joints, the circulatory system and especially the central nervous system. Ocular infections such as keratitis, scleritis, conjunctivitis, dacryocystitis, orbital cellulitis and endophthalmitis due to spp. Read More

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http://dx.doi.org/10.1099/jmmcr.0.005175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421342PMC
February 2019
3 Reads

Corrigendum to "Allergic Conjunctivitis-induced Retinal Inflammation Promotes Myopia Progression" [EBioMedicine 28 (2018) 274-286].

EBioMedicine 2019 Mar 16;41:717-718. Epub 2019 Mar 16.

School of Chinese Medicine, China Medical University, Taichung, Taiwan; Department of Biotechnology, Asia University, Taichung, Taiwan; Department of Obstetrics and Gynecology, China Medical University Hospital, Taichung, Taiwan; Research Center for Chinese Medicine & Acupuncture, China Medical University, Taichung, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.02.046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444068PMC
March 2019
1 Read

Pseudomembranous conjunctivitis: unveil the curtain.

BMJ Case Rep 2019 Mar 15;12(3). Epub 2019 Mar 15.

Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, Delhi, India.

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http://dx.doi.org/10.1136/bcr-2018-228538DOI Listing
March 2019
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Management of dupilumab-associated conjunctivitis in atopic dermatitis.

J Dtsch Dermatol Ges 2019 Mar 15. Epub 2019 Mar 15.

Department of Dermatology and Allergology, University Medical Center, Munich, Germany.

Since September 2017, the monoclonal antibody dupilumab (Dupixent ) has been approved in the EU for the treatment of moderate-to-severe atopic dermatitis. By blocking IL-4 and IL-13 signaling pathways, dupilumab improves both objective signs and subjective symptoms of the disease. Blocking of the IL-4aRα subunit leads to improvement of the skin's barrier function and reduction in Th2-mediated inflammation. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/ddg.13809
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http://dx.doi.org/10.1111/ddg.13809DOI Listing
March 2019
5 Reads

Various Manifestations Of Trachoma In Internally Displaced Rural Population - A Free Eye Camp Based Survey.

J Ayub Med Coll Abbottabad 2019 Jan-Mar;31(1):32-35

Army Field Hospital - Khaleefa Gulnawaz Teaching Hospital Bannu, Pakistan.

Background: The objective of the study is to observe frequency of various clinical manifestations of trachoma in rural population. This observational study was conducted at Khalifa Gul Nawaz Teaching Hospital (KGNTH), Bannu, Pakistan from April 2016 to Jan 2017.

Methods: Patients visiting for ocular complaints underwent initial screening that included demographic details and documentation of unaided as well as best corrected visual acuity (BCVA) which was followed by detailed slit lamp examination of anterior segment including eversion of upper lid for assessment of changes in upper tarsal conjunctivas by consultant ophthalmologist. Read More

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March 2019
4 Reads

Authors:

Arerugi 2019;68(2):107

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http://dx.doi.org/10.15036/arerugi.68.107DOI Listing
January 2019