26,125 results match your criteria Conjunctivitis

Prevalence and characteristics of ocular diseases in Sphynx cats: A retrospective assessment (2012-2021) and comparison with non-Sphynx cats.

Vet Ophthalmol 2022 May 22. Epub 2022 May 22.

Koret School of Veterinary Medicine, The Hebrew University of Jerusalem, Rehovot, Israel.

Purpose: To describe the prevalence of ocular diseases in Sphynx cats, and compare disease characteristics with other feline breeds.

Methods: Medical records of Sphynx cats presented to an ophthalmology referral center between 1/2012 and 4/2021 were examined. Cats of other breeds examined during the same period served as controls. Read More

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Trends in Pediatric Ophthalmic Emergency Department Visits during the COVID-19 Pandemic.

Isr Med Assoc J 2022 May;24(5):289-292

Department of Ophthalmology, Rabin Medical Center (Beilinson Campus), Petah Tikva, Israel.

Background: Data on how the coronavirus disease 2019 (COVID-19) affected consultations in ophthalmic departments are sparse.

Objectives: To examine the epidemiology of ophthalmic consultations in a large pediatric emergency medicine department (PED) during the first nationwide COVID-19 lockdown in Israel.

Methods: The database of a tertiary pediatric medical center was retrospectively reviewed for patients aged < 18 years who attended the PED from 17 March to 30 April 2020 (first COVID-19 lockdown) and the corresponding period in 2019. Read More

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[Ocular abnormalities of children born prematurely at the Yaoundé Gynaeco-Obstetrics And Pediatric Hospital].

J Fr Ophtalmol 2022 May 18. Epub 2022 May 18.

Faculté de médecine et des sciences biomédicales, université de Yaoundé I, Yaoundé, Cameroun; Hôpital gynéco-obstétrique et pédiatrique de Yaoundé, Yaoundé, Cameroun.

Purpose: To identify ocular abnormalities in premature children in order to treat reversible visual disorders and help prevent low vision and blindness in this population at risk.

Methodology: This was a cross-sectional, analytical study carried out from November 1, 2018 to July 31, 2019 at the Yaoundé Gyneco-Obstetric And Pediatric Hospital, including premature children, aged 3 to 15 years. The variables studied were age, sex, prenatal, birth and past ophthalmological history, visual acuity, oculomotor examination and fundus examination. Read More

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Anaphylactic reaction to carboplatin diagnosed by skin testing-a reliable tool in platinum-based immediate-type hypersensitivity reactions.

Wien Med Wochenschr 2022 May 20. Epub 2022 May 20.

Department of Dermatology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

Immediate-type hypersensitivity reactions (IHRs) to carboplatin (CA) are most commonly reported in ovarian cancer patients. A 54-year-old woman with stage IV melanoma suffering from metastasis in the entire right lower extremity was presented to our allergy outpatient clinic for diagnostic work-up due to an anaphylactic reaction with palmoplantar erythema, conjunctivitis along with facial erythema, and an incipient decrease in blood pressure during a chemotherapy regimen with dacarbazine and carboplatin upon re-administration. A subsequently carried out allergological work-up with skin testing (ST) revealed CA to be the culprit drug, whereas cisplatin (CI) was confirmed to be a safe alternative for the patient for following treatments. Read More

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PAF-induced inflammatory and immuno-allergic ophthalmic diseases and their mitigation with PAF receptor antagonists: Cell and nuclear effects.

Najam A Sharif

Biofactors 2022 May 20. Epub 2022 May 20.

Singapore Eye Research Institute (SERI), Singapore, Singapore.

Ocular allergies are becoming more prevalent as more airborne pollutants, irritants and microbes pervade our environment. Inflammatory and allergic mediators released by dendritic and mast cells within the conjunctiva cause allergic conjunctivitis (AC), a prevalent ocular surface disorder that affects >40% of the world's human population on a seasonal or perennial basis. Even though histamine is a major culprit, platelet-activating factor (PAF) also contributes to AC, acting either directly or synergistically with histamine and other mediators. Read More

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Lacrimal Gland Insufficiency in Aqueous Deficiency Dry Eye Disease: Recent Advances in Pathogenesis, Diagnosis, and Treatment.

Semin Ophthalmol 2022 May 19:1-12. Epub 2022 May 19.

The Cornea Institute, L V Prasad Eye Institute, Hyderabad, India.

Background: Aqueous deficiency dry eye disease is a chronic and potentially sight-threatening condition, that occurs due to the dysfunction of the lacrimal glands. The aim of this review was to describe the various recent developments in the understanding, diagnosis and treatment of lacrimal gland insufficiency in aqueous deficiency dry eye disease.

Methods: A MEDLINE database search using PubMed was performed using the keywords: "dry eye disease/syndrome", "aqueous deficient/deficiency dry eye disease", "lacrimal gland" and "Sjogren's syndrome". Read More

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Reproxalap Activity and Estimation of Clinically Relevant Thresholds for Ocular Itching and Redness in a Randomized Allergic Conjunctivitis Field Trial.

Ophthalmol Ther 2022 May 18. Epub 2022 May 18.

Aldeyra Therapeutics, Inc, 131 Hartwell Avenue, Suite 320, Lexington, MA, 02421, USA.

Introduction: This clinical trial assessed the activity of reproxalap, a novel reactive aldehyde species modulator, and estimated clinically relevant thresholds for changes in ocular itching and redness in an allergic conjunctivitis field trial.

Methods: This was a randomized, double-masked, vehicle-controlled phase 2 trial. Patients with ragweed-associated allergic conjunctivitis were assessed over 28 days in an environmental setting with approximately four doses per day of either 0. Read More

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Preparation of a novel tacrolimus ion sensitive ocular in situ gel and evaluation of curative effect of immune conjunctivitis.

Pharm Dev Technol 2022 May 19:1-7. Epub 2022 May 19.

Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China.

Background: The aim of this study was to formulate a novel TAC preparation into an in situ gel for ocular drug delivery, in order to prolong the residence time on mucosal surfaces and increase patient compliance.

Methods: The optimal formulation was characterized by surface morphology, gelling capacity, viscosity, stability and release. studies were also conducted to evaluate the precorneal retention and pharmacodynamic results. Read More

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A Newborn with a Purulent Ocular Discharge.

Pediatr Ann 2022 May 1;51(5):e206-e208. Epub 2022 May 1.

An 11-day-old girl, who was diagnosed with Neisseria gonorrhoeae ophthalmia neonatorum, presents with a purulent ocular discharge. Although rare in regions with high implementation rates of ocular prophylaxis, ophthalmia neonatorum remains an important diagnostic consideration, especially in developing countries and areas of low socioeconomic status. In this article, we review the evolving epidemiology, diagnostic considerations, prevention, and treatment of ophthalmia neonatorum. Read More

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Assessment of corneal endothelial cell morphology and anterior segment parameters in COVID-19.

Ther Adv Ophthalmol 2022 Jan-Dec;14:25158414221096057. Epub 2022 May 9.

Department of Ophthalmology, TOBB ETU School of Medicine, TOBB ETU, Ankara, Turkey.

Background: The ocular manifestations of the 2019 novel coronavirus disease (COVID-19) vary from acute follicular, pseudomembranous, and hemorrhagic conjunctivitis to keratoconjunctivitis with subepithelial infiltrates and dendritic lesions. Similar to other respiratory viruses, such as adenoviruses, it is thought that COVID-19 may impact the cornea. However, its impact on the cornea and anterior segment parameters are currently poorly understood. Read More

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Reactive Arthritis After COVID-19: A Case Report.

Cureus 2022 Apr 13;14(4):e24096. Epub 2022 Apr 13.

Department of Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, SAU.

A 43-year-old healthy male was diagnosed with symptomatic COVID-19. Soon after recovery, he experienced severe back pain, bilateral red eye, and a new penile lesion. He was diagnosed with reactive arthritis, given he presented with arthritis, conjunctivitis, and balanitis. Read More

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A 24-weeks real-world experience of dupilumab in adolescents with moderate-to-severe atopic dermatitis.

Dermatol Ther 2022 May 15:e15588. Epub 2022 May 15.

Department of Health Sciences, University Magna Graecia of Catanzaro, Catanzaro, Italy.

Dupilumab is a monoclonal antibody approved for the treatment of moderate-to-severe atopic dermatitis (AD) in patients aged ≥12years. Large, double-blind, randomised, placebo-controlled trials showed its efficacy and safety in adolescents. However, real-life data are few. Read More

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Efficacy of dupilumab in chronic prurigo and chronic idiopathic pruritus: A systematic review of current evidence and analysis of response predictors.

J Eur Acad Dermatol Venereol 2022 May 15. Epub 2022 May 15.

Department of Dermatology, CHRU de Nancy, 6 rue du Morvan, 54500 Vandœuvre lès, Nancy, France.

Dupilumab has demonstrated a great reduction on chronic pruritus that is the hallmark of atopic dermatitis (AD). Underscoring relevant pathogenesis similarities emerging from AD, chronic idiopathic pruritus (CIP) and chronic prurigo (CP), several authors suggested the beneficial role of dupilumab in these conditions. The evidence on this subject is limited with no precise data available. Read More

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Impact of screen exposure on pediatric vernal Keratoconjunctivitis: a survey during the COVID-19 pandemic in Italy.

Ital J Pediatr 2022 May 14;48(1):74. Epub 2022 May 14.

Department of Maternal Infantile and Urological Sciences, Division of Pediatric Allergology and Immunology, Sapienza University of Rome, 00185, Rome, Italy.

Background: The SARS-CoV-2 outbreak pushed the Italian government to start a strict lockdown, replacing school attendance with long-distance learning. This caused reduced exposure to sunlight but increased exposure to screens. Vernal keratoconjunctivitis (VKC) is a chronic inflammatory ocular condition in which exposure to light plays a cardinal role. Read More

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ILCs and Allergy.

Adv Exp Med Biol 2022 ;1365:75-95

Laboratory for Innate Immune Systems, RIKEN Center for Integrative Medical Sciences (IMS), Kanagawa, Japan.

The recent discovery of new innate lymphoid cells (ILCs) has revolutionized the field of allergies. Since most allergic diseases induce a type 2 immune response, Th2 cells, which produce IL-4, IL-5, and IL-13 in an antigen-dependent manner, in addition to basophils and mast cells which are activated by antigen-specific IgE, are thought to play a major role in the pathogenesis. However, since group 2 innate lymphoid cells (ILC2s) produce type 2 cytokines (i. Read More

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Aqueous-Deficient Dry Eye Exacerbates Signs and Symptoms of Allergic Conjunctivitis in Mice.

Int J Mol Sci 2022 Apr 28;23(9). Epub 2022 Apr 28.

Department of Ophthalmology and Visual Science, Kochi Medical School, Kochi University, Kochi 783-8505, Japan.

Dry eye disease (DED) and allergic conjunctivitis affect a large number of patients, and many patients usually have both symptoms. We investigated the interactions between DED and allergic conjunctivitis in mice. Four experimental groups were compared: control, DED, allergy, and allergy with DED. Read More

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Recent large-scale philophthalmosis outbreak in Portugal: inefficacy of common antihelminthic agents.

Parasit Vectors 2022 May 12;15(1):167. Epub 2022 May 12.

Wildlife Rehabilitation and Research Center of Ria Formosa (RIAS), Ria Formosa Natural Park, Olhão, Portugal.

Background: Parasitic conjunctivitis caused by Philophthalmus spp. is a common ophthalmic disease in birds, with localized outbreaks occurring worldwide. There is no consensus on treating this disease; mechanical removal is considered a standard recommendation, but is associated with disease relapses within days or weeks. Read More

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Epidemiological Investigation and Risk Factor Analysis of Acute Hemorrhagic Conjunctivitis in Huangshi Port District, Huangshi City.

Juan Liu Hui Zhang

Comput Math Methods Med 2022 2;2022:3009589. Epub 2022 May 2.

Technical Service Center, Kunming Center for Disease Control and Prevention, Kunming, Yunnan 650034, China.

Objective: This study is aimed at investigating the epidemiology and risk factors of acute hemorrhagic conjunctivitis (pinkeye) in Huangshi Port District of Huangshi City.

Methods: A total of 593 cases of acute hemorrhagic conjunctivitis from January 2019 to December 2021 were selected as the observation group. The epidemiological characteristics (age of onset, season, occupation, clinical manifestations, and etiological characteristics) were analyzed. Read More

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Evaluation of knowledge, attitude, and behaviour of ophthalmologists about adenoviral conjunctivitis transmission and treatment : An online survey for Turkish ophthalmologists.

Int Ophthalmol 2022 May 11. Epub 2022 May 11.

Department of Ophthalmology, Ege University Medicine Faculty, İzmir, Turkey.

Purpose: To determine the prevalence of adenoviral conjunctivitis in Turkish ophthalmologists, to provide an overview of the treatment and prophylaxis of adenoviral conjunctivitis, and to analyze the data in the context of evidence-based treatment recommendations.

Methods: An online questionnaire consisting of 20 multiple-choice questions about the characteristics of the respondents, the individual adenoviral conjunctivitis history of the ophthalmologists, their practice's approaches, and prescription preferences were emailed to Turkish ophthalmologists.

Results: The survey was emailed to 500 ophthalmologists; 45% of them returned the questionnaire. Read More

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Ophthalmology emergency department visits in a Brazilian tertiary hospital over the last 11 years: data analysis.

Arq Bras Oftalmol 2022 May 9. Epub 2022 May 9.

Department of Ophthalmology, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.

Purpose: This study aimed to describe the visits profile to Hospital São Paulo's ophthalmology emergency department, a 24-hour public open-access tertiary-care service in São Paulo, Brazil, that belongs to Federal University of São Paulo, over the last 11 years.

Methods: A cross-sectional retrospective study was conducted, including all patients (n=634,726) admitted to the ophthalmology emergency department of Hospital São Paulo between January 2009 and December 2019.

Results: From 2009 to 2019, the number of patients' presentations increased to 39. Read More

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The importance of considering the possibility of ocular sporotrichosis in areas with high incidence rates of sporotrichosis.

Arq Bras Oftalmol 2022 May 9. Epub 2022 May 9.

Ophthalmology Service, Hospital do Servidor Público Estadual de São Paulo, São Paulo, SP, Brazil.

Ocular sporotrichosis involving adnexa can present in 4 types: granulomatous conjunctivitis, dacryocystitis, Parinaud oculoglandular syndrome, and bulbar conjunctivitis. The incidence of ocular sporotrichosis has increased in regions with high incidence rates of sporotrichosis. We present a series of three cases of ocular involvement by the fungus Sporothrix species, including its manifestations, approaches, and relevance in areas where sporotrichosis has considerable incidence rates. Read More

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Phototherapeutic keratectomy: current approaches and changing trends in a tertiary eye clinic.

Arq Bras Oftalmol 2022 May 9. Epub 2022 May 9.

Department of Ophthalmology, Beyoglu Eye Training and Research Hospital, University of Health Sciences Turkey, Istanbul, Turkey.

Purpose: To examine the efficacy of phototherapeutic keratectomy as a treatment for variable pathologies with anterior corneal opacities and evaluate the distribution of phototherapeutic keratectomy indications over the past 10 years.

Methods: The records of 334 eyes from 276 patients who underwent phototherapeutic keratectomy between March 2010 and 2020 were retrospectively reviewed. Etiologies of the patients who underwent phototherapeutic keratectomy were noted, and their changes were examined. Read More

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Eye diseases during pregnancy: a study with the medical data warehouse in the eye clinic of the Ludwig-Maximilians-Universität München in Munich in Germany.

Einstein (Sao Paulo) 2022 6;20:eAO6613. Epub 2022 May 6.

Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.

Objective: To analyze the most common ophthalmologic disorders in pregnant women seen in a hospital in Munich in Germany using a big data analysis system, as well as to compare the results obtained with those from other epidemiological studies that used different data acquisition methods.

Methods: We retrospectively analyzed electronic health records of pregnant women who were seen at the ophthalmology department from 2003 to 2019 at the Ludwig-Maximilians-Universität München hospital. The main complaints that led to ophthalmic consultations during this period were evaluated, and also the variation in intraocular pressure of patients throughout gestational trimesters by analyzing data from the data warehouse system. Read More

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Epidemiology, Clinical Features, and Outcomes of Multisystem Inflammatory Syndrome in Children (MIS-C) and Adolescents-a Live Systematic Review and Meta-analysis.

Curr Pediatr Rep 2022 May 6:1-12. Epub 2022 May 6.

Centre for Global Child Health, Hospital for Sick Children, Toronto, Canada.

Purpose Of Review: A multisystem inflammatory condition occurring in children and adolescents with COVID-19 has become increasingly recognized and widely studied globally. This review aims to investigate and synthesize evolving evidence on its clinical characteristics, management, and outcomes in pediatric patients.

Recent Findings: We retrieved data from PubMed, EMBASE, Cochrane Library, WHO COVID-19 Database, Google Scholar, and preprint databases, covering a timeline from December 1, 2019, to July 31, 2021. Read More

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Distinct Diurnal and Day of Week Online Search Patterns Related to Common Eye Conditions: A Google Trends Approach.

J Med Internet Res 2022 May 6. Epub 2022 May 6.

F. I. Proctor Foundation, Department of Ophthalmology, and Department of Epidemiology and Biostatistics, Global Health Sciences, University of California, San Francisco, 490 Illinois St, Floor 2Box 0944, San Francisco, US.

Background: Studies suggest diurnal patterns of occurrence of some eye conditions. Leveraging new information sources such as online search data to learn more about such patterns could improve understanding of patient eye-related conditions and well-being, better inform timing of clinical and remote eye care, and improve precision when targeting online public health campaigns towards underserved populations.

Objective: To investigate our hypothesis that the public is likely to consistently search about different ophthalmologic conditions at different hours of the day or days of week, we conducted an observational study using search data for terms related to ophthalmologic conditions such as conjunctivitis. Read More

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Improvement of dupilumab-associated conjunctivitis after switching to upadacitinib in a patient with atopic dermatitis.

Dermatol Ther 2022 May 10:e15575. Epub 2022 May 10.

Division of Cutaneous Science, Department of Dermatology, Nihon University School of Medicine, Tokyo, Japan.

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Atopic Dermatitis and the Medications Used for its Management: Impact on Ocular Health.

J Drugs Dermatol 2022 May;21(5):523-525

Atopic Dermatitis (AD) is one of the most common inflammatory skin conditions. AD is generally characterized by eczematous and pruritic skin lesions, although it can present differently between individuals. There are multiple comorbidities for AD, including asthma, food allergies, and ocular disorders such as conjunctivitis. Read More

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Relationship between allergic rhinitis and allergic conjunctivitis (allergic rhinoconjunctivitis) - review.

Rom J Ophthalmol 2022 Jan-Mar;66(1):8-12

Clinical Ophthalmology Emergency Hospital, Bucharest, Romania.

Allergic rhinitis and allergic conjunctivitis are so frequently associated that the need to coin a new name to describe the simultaneous manifestations generated the term allergic rhinoconjunctivitis. The significant impact of rhinoconjunctivitis on the quality of life and the wellbeing of the patients is the reason why the medical community shows a great interest to this disease. Another aspect is the financial burden that is not negligible. Read More

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