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    3630 results match your criteria Congestive Heart Failure and Pulmonary Edema

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    DJ-1 activates autophagy in the repression of cardiac hypertrophy.
    Arch Biochem Biophys 2017 Sep 20. Epub 2017 Sep 20.
    Department of Cardiology, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China; Key Laboratory on Assisted Circulation, Ministry of Health, Guangzhou, China. Electronic address:
    Cardiac hypertrophy is the risk factor of heart failure when the heart is confronted with pressure overload or neurohumoral stimuli. Autophagy, a conserved degradative pathway, is one of the important mechanisms involved in the regulation of cardiac hypertrophy. DJ-1 is a traditional anti-oxidative protein and emerging evidence suggested that DJ-1 might modulate autophagy. Read More

    Epidemiology, pathogenesis, and management of takotsubo syndrome.
    Clin Auton Res 2017 Sep 15. Epub 2017 Sep 15.
    Department of Clinical Science and Education Södersjukhuset, Karolinska Institutet, Sjukhusbacken 10, 118 83, Stockholm, Sweden.
    Takotsubo syndrome is a recently recognized acute cardiac disease entity with a clinical presentation resembling that of an acute coronary syndrome. The typical takotsubo syndrome patient has a unique circumferential left (bi-) ventricular contraction abnormality profile that extends beyond a coronary artery supply territory and appears to follow the anatomical cardiac sympathetic innervation. The syndrome predominantly affects postmenopausal women and is often preceded by emotional or physical stress. Read More

    Percutaneous extracorporeal membrane oxygenation in electrical storm: five case reports addressing efficacy, transferring allowance or radiofrequency ablation support.
    Eur Heart J Acute Cardiovasc Care 2017 Sep 1:2048872617730036. Epub 2017 Sep 1.
    Department of Cardiology, University Hospital of Salamanca - IBSAL, Salamanca, Spain.
    Extracorporeal membrane oxygenation systems have undergone rapid technological improvements and are now feasible options for medium-term support of severe cardiac or pulmonary failure. We report five cases of electrical storm that was rescued by the insertion of peripheral veno-arterial extracorporeal membrane oxygenation systems. This device could help to restore systemic circulation as well as permitting organ perfusion in patients with cardiogenic shock in relation to electrical storm thus achieving greater electrical stability. Read More

    State-wide reduction in in-hospital cardiac complications in association with the introduction of a national standard for recognising deteriorating patients.
    Resuscitation 2017 Aug 30. Epub 2017 Aug 30.
    Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, The Alfred Centre, 99 Commercial Road, Melbourne, VIC 3004, Australia.
    Aim: To examine whether introducing a national standard to improve the recognition of and response to clinical deterioration, was associated with a reduction in cardiovascular events in the hospital environment.

    Method: Interrupted time series was used to analyse the trajectories of monthly complication rates for 4.69 million admissions in 218 hospitals. Read More

    Acute and Midterm Outcomes of Transcatheter Pulmonary Valve Replacement for Treatment of Dysfunctional Left Ventricular Outflow Tract Conduits in Patients With Aortopulmonary Transposition and a Systemic Right Ventricle.
    Circ Cardiovasc Interv 2017 Sep;10(9)
    From the Heart Institute, Cincinnati Children's Hospital Medical Center, OH (W.W., J.T.T., C.M.M., B.H.G.); Division of Cardiology, Ahmanson/Adult Congenital Heart Disease Center, Los Angeles, CA (J.A.); Division of Pediatric Cardiology, Department of Pediatrics, University of Iowa Children's Hospital (O.A.); Division of Pediatric Cardiology, Department of Pediatrics, University of Michigan C. S. Mott Children's Hospital, Ann Arbor (A.K.A., M.L.B.); Division of Cardiology, the Children's Hospital of Philadelphia, PA (M.J.G.); Seattle Children's Hospital, University of Washington (T.K.J.); Division of Cardiology, Department of Pediatrics, University of Utah, Salt Lake City (M.H.M.); Division of Cardiology, UCSF Benioff Children's Hospital, University of California (J.J.M.); Division of Pediatric Cardiology, Columbia University College of Physicians and Surgeons, Morgan Stanley Children's Hospital of New York Presbyterian (M.E.T.); and Division of Cardiology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas (T.Z.).
    Background: Transcatheter pulmonary valve replacement (TPVR) is an established therapy for dysfunctional right ventricular (RV) outflow tract conduits. TPVR in patients with congenitally corrected transposition of the great arteries, subpulmonary left ventricle, and left ventricular outflow tract (LVOT) conduit dysfunction has not been studied. Unique anatomic and physiological aspects of this population may contribute to distinct risks and outcomes. Read More

    The lung water cascade in heart failure.
    Echocardiography 2017 Aug 28. Epub 2017 Aug 28.
    Nottola Hospital, Siena, and Cardiothoracic Department, Pisa University Hospital, Pisa, Italy.
    In heart failure patients, we hypothesize the occurrence of the "lung water cascade," with the various markers hierarchically ranked in a well-defined time sequence: (1) early, proximal hemodynamic event with increase in pulmonary capillary wedge pressure; (2) intermediate, direct imaging sign of pulmonary edema (easily detectable at bedside by lung ultrasound as B-lines); (3) late, distal clinical symptoms and signs such as dyspnea and pulmonary crackles. Completion of the cascade (from hemodynamic to pulmonary to clinical congestion) can require minutes (as with exercise), hours or even weeks (as with impending acute heart failure). Backward rewind of the downhill cascade can be achieved with timely pulmonary decongestion therapy, such as diuretics or dialysis, restoring a relatively dry lung. Read More

    A systematic review of diagnostic methods to differentiate acute lung injury/acute respiratory distress syndrome from cardiogenic pulmonary edema.
    Crit Care 2017 Aug 25;21(1):228. Epub 2017 Aug 25.
    Children's Hospital of Richmond at Virginia Commonwealth, Richmond, VA, 23298, USA.
    Background: Discriminating acute lung injury (ALI) or acute respiratory distress syndrome (ARDS) from cardiogenic pulmonary edema (CPE) is often challenging. This systematic review examines studies using biomarkers or images to distinguish ALI/ARDS from CPE.

    Methods: Three investigators independently identified studies designed to distinguish ALI/ARDS from CPE in adults. Read More

    Cardio-Pulmonary Interactions: Physiologic Basis and Clinical Applications.
    Ann Am Thorac Soc 2017 Aug 18. Epub 2017 Aug 18.
    University of Pittsburgh Medical Center, Critical Care Medicine , Professor of Critical Care Medicine and Bioengineering , 606 Scaife Hall , 3550 Terrace Street , Pittsburgh, Pennsylvania, United States , 15261 ;
    The hemodynamic effects of ventilation can be grouped into three concepts: 1) spontaneous ventilation is exercise; 2) changes in lung volume alter autonomic tone, pulmonary vascular resistance, and can compress the heart in the cardiac fossa; 3) spontaneous inspiratory efforts decrease intrathoracic pressure (ITP) increasing venous return and impeding left ventricular (LV) ejection; whereas positive pressure ventilation decreases venous return and unloads LV ejection. Spontaneous inspiratory efforts may induce acute LV failure and cardiogenic pulmonary edema. Reversing the associated negative ITP swings by using non-invasive continuous positive airway pressure rapidly reverses acute cardiogenic pulmonary edema and improves survival. Read More

    Intratracheal administration of isosorbide dinitrate improves pulmonary artery pressure and ventricular remodeling in a rat model of heart failure following myocardial infarction.
    Exp Ther Med 2017 Aug 28;14(2):1399-1408. Epub 2017 Jun 28.
    Department of Cardiology, Huadong Hospital Affiliated to Fudan University, Shanghai 200040, P.R. China.
    Pulmonary hypertension due to left heart disease is associated with poor outcomes. This study investigated the beneficial effects of isosorbide dinitrate (ISDN) inhalation on pulmonary pressure and ventricular remodeling in a rat model of heart failure (HF) following myocardial infarction (MI). To assess the effect of ISDN on pulmonary pressure, 20 male Sprague-Dawley (SD) rats were randomized to four groups: Normal saline (NS) 1 ml/kg, ISDN 1 mg/kg, NS 3 ml/kg or ISDN 3 mg/kg following coronary ligation. Read More

    Severe reversible hypocalcemic cardiomyopathy diagnosed 36 years after subtotal thyroidectomy - a case report.
    Pol Merkur Lekarski 2017 Jul;43(253):26-31
    Department of Internal Medicine, Józef Struś Hospital, Poznań, Poland.
    Chronic hypocalcemia, irrespectively of its etiology, can lead to severe impairment of the left ventricular (LV) contractility manifesting as dilated cardiomyopathy, usually defined as hypocalcemic cardiomyopathy (hypocaCM). This rarely diagnosed type of heart failure (HF), can be completely reversible, when treated properly with calcium and vitamin D supplementation or, in some subjects, with human recombinant parathormone.

    A Case Report: The authors present a case of a 60-year-old male admitted with advanced pulmonary congestion, recurrent pulmonary edema and pleural effusion. Read More

    Adverse Heart-lung Interactions in Ventilator-induced Lung Injury.
    Am J Respir Crit Care Med 2017 Aug 10. Epub 2017 Aug 10.
    Hospital Sick Children, Department of Critical Care Medicine, Toronto, Ontario, Canada ;
    Rationale: The original in vivo study of ventilator-induced lung injury by Webb and Tierney (1974) reported that high VT with zero PEEP caused overwhelming lung injury, subsequently shown by others to be due to lung shear stress.

    Objective: To reproduce the lung injury and edema in the 'Webb and Tierney' study and investigate the mechanism.

    Methods: Sprague-Dawley rats (≈400 g) received mechanical ventilation for 60 min according to the protocol of Webb and Tierney (14/0, 30/0, 45/10, 45/0 cmH2O). Read More

    Current Status of Renal Artery Angioplasty and Stenting for Resistant Hypertension: A Case Series and Review of the Literature.
    Curr Hypertens Rev 2017 Aug 4. Epub 2017 Aug 4.
    Onassis Cardiac Surgery Center, Athens. Greece.
    Background: Renal artery stenosis (RAS) has a high prevalence in older patients, especially in the context of general atherosclerosis. It is frequently associated with resistant hypertension and impaired renal function and their attendant consequences. The issue whether revascularization via percutaneous renal angioplasty and stenting (PRA/S) can benefit these patients remains unsettled. Read More

    Acute heart failure and rhabdomyolysis: a clue for the diagnosis of polymyositis with cardiac involvement.
    Reumatismo 2017 Aug 3;69(2):78-83. Epub 2017 Aug 3.
    Department of Internal Medicine, Centro Hospitalar São João, Porto.
    Polymyositis is an idiopathic inflammatory myopathy, characterized by proximal muscle weakness and sometimes extramuscular manifestations. We report the case of a 51-year-old male, with history of complete heart block, which required pacemaker implantation, and subsequently heart failure, presenting to the emergency department with worsening of dyspnea and peripheral edema. He was admitted to the Internal Medicine ward with acute heart failure and started on diuretic therapy. Read More

    Acute pulmonary edema in patients with reduced left ventricular ejection fraction is associated with concentric left ventricular geometry.
    Int J Cardiovasc Imaging 2017 Aug 2. Epub 2017 Aug 2.
    Division of Cardiovascular Medicine, Department of Internal Medicine, Shinko Hospital, 1-4-47, Wakihama-cho, Chuo-ku, Kobe, 650-0072, Japan.
    Although acute pulmonary edema (APE) is common in patients with heart failure (HF) with preserved ejection fraction (EF), its pathogenesis in patients with HF with reduced EF (HFrEF) is not completely understood. The purpose of our study was to explore the contributions of left ventricular (LV) geometry to understand the difference between HFrEF patients with or without APE. We studied 122 consecutive acute decompensated HF patients with HFrEF (≤40%). Read More

    Serial Sonographic Assessment of Pulmonary Edema in Patients With Hypertensive Acute Heart Failure.
    J Ultrasound Med 2017 Jul 31. Epub 2017 Jul 31.
    State University of New York Downstate Medical Center, Brooklyn, New York, USA.
    Objectives: Objective measures of clinical improvement in patients with acute heart failure (AHF) are lacking. The aim of this study was to determine whether repeated lung sonography could semiquantitatively capture changes in pulmonary edema (B-lines) in patients with hypertensive AHF early in the course of treatment.

    Methods: We conducted a feasibility study in a cohort of adults with acute onset of dyspnea, severe hypertension in the field or at triage (systolic blood pressure ≥ 180 mm Hg), and a presumptive diagnosis of AHF. Read More

    Survival and neurological outcome in the elderly after in-hospital cardiac arrest.
    Resuscitation 2017 Sep 20;118:101-106. Epub 2017 Jul 20.
    University Hospital of Iceland, Reykjavik, Iceland.
    Background: There have been few studies of the outcome in elderly patients who have suffered in-hospital cardiac arrest (IHCA) and the association between cardiac arrest characteristics and survival.

    Aim: The aim of this large observational study was to investigate the survival and neurological outcome in the elderly after IHCA, and to identify which factors were associated with survival.

    Methods: We investigated elderly IHCA patients (≥70years of age) who were registered in the Swedish Cardiopulmonary Resuscitation Registry 2007-2015. Read More

    Is the mechanism of re-expansion pulmonary oedema in a heart-lung interaction?
    BMJ Case Rep 2017 Jul 18;2017. Epub 2017 Jul 18.
    Department of Anaesthesia and Intensive Care, 1st Medical Faculty, Charles University, Prague, Czech Republic.
    The mechanism of re-expansion pulmonary oedema (Re-PE) is unclear. There are multiple variables in play when evaluating the response to evacuation of pleural fluid. We present an educational case of a critically ill patient admitted for respiratory failure who was fully dependent on ventricular pacing set at a constant rate throughout the episode of Re-PE. Read More

    The Transition From Hypertension to Heart Failure: Contemporary Update.
    JACC Heart Fail 2017 Aug 12;5(8):543-551. Epub 2017 Jul 12.
    Leon H. Charney Division of Cardiology, New York University School of Medicine, New York, New York.
    Longstanding hypertension ultimately leads to heart failure (HF), and, as a consequence most patients with HF have a history of hypertension. Conversely, absence of hypertension in middle age is associated with lower risks for incident HF across the remaining life course. Cardiac remodeling to a predominant pressure overload consists of diastolic dysfunction and concentric left ventricular (LV) hypertrophy. Read More

    When Is the Optimal Timing of Surgical Intervention for Severe Functional Tricuspid Regurgitation?
    Case Rep Cardiol 2017 19;2017:9232658. Epub 2017 Jun 19.
    Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
    Functional tricuspid regurgitation (TR) is a serious pathology to be noted for severe right heart failure (HF) and poor prognosis; however, the conventional assessment of TR has some limitations and the optimal timing of surgical intervention remains unclear. A 79-year-old Japanese female was admitted to our hospital to undergo cardiac surgery, because edema gradually got worse despite the increase in diuretics. She had a history of atrial fibrillation (AF) and chronic HF due to severe TR and had been treated with a furosemide for leg edema 4 years ago. Read More

    The impact of hemodialysis schedules on the day of the week of hospitalization for cardiovascular and infectious diseases, over a period of 20 years.
    PLoS One 2017 10;12(7):e0180577. Epub 2017 Jul 10.
    Department of Artificial Organs, Akane-Foundation, Tsuchiya General Hospital, Hiroshima, Japan.
    There have been no studies as yet that have evaluated how hemodialysis (HD) schedules affect the day of the week of hospitalization for cardiovascular diseases (CVDs) and infectious diseases (IDs), over a period of time. Herein, we performed a retrospective observational cohort study (1995-2014) evaluating 11,111 hospitalizations in 1,953 patients with end-stage renal disease, receiving HD 3 times a week (following either a Monday-Wednesday-Friday [MWF] schedule or a Tuesday-Thursday-Saturday [TTS] schedule) or receiving frequent HD (FHD) at least 4 times a week. Overall, hospitalization rates for CVDs and IDs were the highest on Monday in the MWF schedule and Tuesday in the TTS schedule compared to the average rates for all the days of the week. Read More

    Comparing volume-clamp method and intra-arterial blood pressure measurements in patients with atrial fibrillation admitted to the intensive or medium care unit.
    J Clin Monit Comput 2017 Jul 7. Epub 2017 Jul 7.
    Department of Internal Medicine, VU University Medical Center, Amsterdam, The Netherlands.
    International guidelines highlight the importance of blood pressure (BP) in patients with atrial fibrillation (AF). However, BP measurement in AF is complicated by beat-to-beat fluctuation. Automated BP measurement devices are not validated for patients with AF and no consensus exists on how to measure BP in AF manually. Read More

    Restoration of Megalin-mediated Clearance of Alveolar Protein as a Novel Therapeutic Approach for Acute Lung Injury.
    Am J Respir Cell Mol Biol 2017 Jul 5. Epub 2017 Jul 5.
    Justus Liebig University, Universities of Giessen and Marburg Lung Center, Member of the German Center for Lung Research, Department of Internal Medicine, Giessen, Germany ;
    Acute respiratory distress syndrome (ARDS) constitutes a significant disease burden with regard to both morbidity and mortality. Current therapies are mostly supportive and do not address the underlying pathophysiologic mechanisms. Removal of protein-rich alveolar edema - a clinical hallmark of ARDS - is critical for survival. Read More

    Involvement of Cytokines in the Pathogenesis of Salt and Water Imbalance in Congestive Heart Failure.
    Front Immunol 2017 19;8:716. Epub 2017 Jun 19.
    Department of Physiology and Biophysics, Technion, Israel Institute of Technology, Haifa, Israel.
    Congestive heart failure (CHF) has become a major medical problem in the western world with high morbidity and mortality rates. CHF adversely affects several systems, mainly the kidneys and the lungs. While the involvement of the renin-angiotensin-aldosterone system and the sympathetic nervous system in the progression of cardiovascular, pulmonary, and renal dysfunction in experimental and clinical CHF is well established, the importance of pro-inflammatory mediators in the pathogenesis of this clinical setting is still evolving. Read More

    Characteristics of Patients With Congestive Heart Failure or Chronic Obstructive Pulmonary Disease Readmissions Within 30 Days Following an Acute Exacerbation.
    Qual Manag Health Care 2017 Jul/Sep;26(3):152-159
    Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock.
    Background: The Hospital Readmissions Reduction Program targets Medicare patients with congestive heart failure (CHF) and chronic obstructive pulmonary disease (COPD) and penalizes hospitals that have increased 30-day readmission rates for these patients. The main goals of this study were to determine the clinical explanations for readmissions within 30 days, to identify possible deficiencies in patient care, and to identify typical characteristics of patients who were readmitted to the hospital.

    Methods: The medical records department at University Medical Center in Lubbock, Texas, generated a list of patients with a primary discharge diagnosis of either acute exacerbation of CHF or an acute exacerbation of COPD who were readmitted within 30 days of discharge. Read More

    Lung fluid clearance in chronic heart failure patients.
    Int J Cardiol 2017 Oct 26;244:245-247. Epub 2017 May 26.
    Intensive and Critical Care Unit, Flinders Medical Centre, Adelaide, Australia; Department of Critical Care Medicine, Flinders University, Adelaide, Australia.
    Chronic elevation of pulmonary microvascular pressure (Pmv) consistently leads to alveolocapillary barrier thickening and reduction in the filtration coefficient. In animal models of chronic heart failure (CHF) the lung remains dry despite hydrostatic forces. As fluid flux is bi-directional, it has been postulated that an increase in alveolar fluid clearance may facilitate the dry lung when Pmv is chronically elevated. Read More

    Incremental prognostic value of a complex left ventricular remodeling classification in asymptomatic for heart failure hypertensive patients.
    J Am Soc Hypertens 2017 Jul 25;11(7):412-419. Epub 2017 May 25.
    Dipartimento di Patologia Medica, Chirurgica, Molecolare e dell'Area Critica, Università di Pisa, Pisa, Italy.
    We evaluated the prognostic impact of a complex remodeling classification (CRC) in asymptomatic patients with arterial hypertension (AH). We retrospectively included 749 hypertensive patients (female 325, 43.4% age 62 ± 11. Read More

    Pulmonary congestion evaluated by lung ultrasound predicts decompensation in heart failure outpatients.
    Int J Cardiol 2017 Aug;240:271-278
    Institute of Clinical Physiology, National Research Council of Pisa, Italy.
    Background: Pulmonary congestion is the main cause of hospital admission among heart failure (HF) patients. Lung ultrasound (LUS) assessment of B-lines has been recently proposed as a reliable and easy tool for evaluating pulmonary congestion.

    Objective: To determine the prognostic value of LUS in predicting adverse events in HF outpatients. Read More

    [The Value of Early Diastolic Transmitral Velocity to Early Mitral Anulus Diastolic Velocity Ratio for Pulmonary Edema in Severe Sepsis Patients].
    Sichuan Da Xue Xue Bao Yi Xue Ban 2016 Jul;47(4):580-583
    Department of Critical Care Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.
    Objectives: To determine the association between the value of early diastolic transmitral velocity to early mitral anulus diastolic velocity ratio (E/E')measured by bedside ultrasound and pulmonary edema in severe sepsis (including septic shock) patients.

    Methods: Data were obtained from the critical ultrasound database between November 2014 and August 2015. The severe sepsis (including septic shock) patients were eligible, but those with chronic heart disease or acute heart failure were excluded. Read More

    Intra-aortic balloon pump protects against hydrostatic pulmonary oedema during peripheral venoarterial-extracorporeal membrane oxygenation.
    Eur Heart J Acute Cardiovasc Care 2017 Jun 1:2048872617711169. Epub 2017 Jun 1.
    1 Medical-Surgical ICU, Hôpital Pitié-Salpêtrière, France.
    Background: Increased left ventricular afterload during peripheral venoarterial-extracorporeal membrane oxygenation (VA-ECMO) support frequently causes hydrostatic pulmonary oedema. Because physiological studies demonstrated left ventricular afterload decrease during VA-ECMO assistance combined with the intra-aortic balloon pump (IABP), we progressively changed our standard practice systematically to associate an IABP with VA-ECMO. This study aimed to evaluate IABP efficacy in preventing pulmonary oedema in VA-ECMO-assisted patients. Read More

    Does an electronic cognitive aid have an effect on the management of severe gynaecological TURP syndrome? A prospective, randomised simulation study.
    BMC Anesthesiol 2017 May 30;17(1):72. Epub 2017 May 30.
    Anästhesiologische Klinik, Universitätsklinikum Erlangen, Krankenhaustrasse 12, 91054, Erlangen, Germany.
    Background: Lack of familiarity with the content of current guidelines is a major factor associated with non-compliance by clinicians. It is conceivable that cognitive aids with regularly updated medical content can guide clinicians' task performance by evidence-based practices, even if they are unfamiliar with the actual guideline. Acute hyponatraemia as a consequence of TURP syndrome is a rare intraoperative event, and current practice guidelines have changed from slow correction to rapid correction of serum sodium levels. Read More

    Discovery of GSK2193874: An Orally Active, Potent, and Selective Blocker of Transient Receptor Potential Vanilloid 4.
    ACS Med Chem Lett 2017 May 20;8(5):549-554. Epub 2017 Mar 20.
    GlaxoSmithKline, Heart Failure Discovery Performance Unit, Metabolic Pathways and Cardiovascular Therapeutic Area, King of Prussia, Pennsylvania 19406, United States.
    Transient Receptor Potential Vanilloid 4 (TRPV4) is a member of the Transient Receptor Potential (TRP) superfamily of cation channels. TRPV4 is expressed in the vascular endothelium in the lung and regulates the integrity of the alveolar septal barrier. Increased pulmonary vascular pressure evokes TRPV4-dependent pulmonary edema, and therefore, inhibition of TRPV4 represents a novel approach for the treatment of pulmonary edema associated with conditions such as congestive heart failure. Read More

    Central-acting therapeutics alleviate respiratory weakness caused by heart failure-induced ventilatory overdrive.
    Sci Transl Med 2017 May;9(390)
    Department of Human Health and Nutritional Science, University of Guelph, Guelph, Ontario N1G 2W1, Canada.
    Diaphragmatic weakness is a feature of heart failure (HF) associated with dyspnea and exertional fatigue. Most studies have focused on advanced stages of HF, leaving the cause unresolved. The long-standing theory is that pulmonary edema imposes a mechanical stress, resulting in diaphragmatic remodeling, but stable HF patients rarely exhibit pulmonary edema. Read More

    Percutaneous left atrial decompression in adults with refractory cardiogenic shock supported with veno-arterial extracorporeal membrane oxygenation.
    J Card Surg 2017 Jun 11;32(6):396-401. Epub 2017 May 11.
    Division of Cardiology, Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario.
    Background And Aim Of The Study: Left ventricular (LV) distention, a recognized complication in patients supported with veno-arterial extracorporeal membrane oxygenation (VA-ECMO) for refractory cardiogenic shock, can lead to pulmonary edema, increased myocardial oxygen consumption, and LV thrombus formation. Atrial septostomy was examined as a management strategy for LV distension.

    Methods: Of 72 patients supported with VA-ECMO, seven patients underwent atrial septostomy through a trans-septal approach. Read More

    Atrial Septostomy for Left Atrial Decompression During Extracorporeal Membrane Oxygenation by Inoue Balloon Catheter.
    Circ J 2017 Sep 11;81(10):1419-1423. Epub 2017 May 11.
    Division of Cardiovascular Medicine, Department of Medicine, China Medical University Hospital.
    Background: Refractory pulmonary edema is an infrequent but serious complication in patients receiving venoarterial extracorporeal membrane oxygenation (VA-ECMO) for myocardial failure. Left atrial (LA) decompression in this setting is important. Although a few methods have been reported, the experience is mostly limited to children. Read More

    Left Atrial Size and Heart Failure Hospitalization in Patients with Diastolic Dysfunction and Preserved Ejection Fraction.
    J Cardiovasc Echogr 2017 Jan-Mar;27(1):1-6
    Columbia University Division of Cardiology, Mount Sinai Medical Center, Miami Beach, FL, USA.
    Context: Heart failure with preserved ejection fraction (HFpEF) is a clinical syndrome associated with diastolic function abnormalities. It remains unclear which factors, if any, can predict the transition from asymptomatic diastolic dysfunction to an overt symptomatic phase.

    Materials And Methods: Patients hospitalized with suspected heart failure between January 2012 and November 2014 with a transthoracic echocardiogram demonstrating preserved systolic function were screened (n = 425). Read More

    Clinical phenotypes and outcome of patients hospitalized for acute heart failure: the ESC Heart Failure Long-Term Registry.
    Eur J Heart Fail 2017 Apr 30. Epub 2017 Apr 30.
    ANMCO Research Center, Florence, Italy.
    Aims: To identify differences in clinical epidemiology, in-hospital management and 1-year outcomes among patients hospitalized for acute heart failure (AHF) and enrolled in the European Society of Cardiology Heart Failure Long-Term (ESC-HF-LT) Registry, stratified by clinical profile at admission.

    Methods And Results: The ESC-HF-LT Registry is a prospective, observational study collecting hospitalization and 1-year follow-up data from 6629 AHF patients. Among AHF patients enrolled in the registry, 13. Read More

    Chronic Atrial Fibrillation Ablation with Harmonic Scalpel during Mitral Valve Surgery.
    Braz J Cardiovasc Surg 2017 Jan-Feb;32(1):22-28
    Faculdade de Medicina de São José do Rio Preto (FAMERP), São José do Rio Preto, SP, Brazil and Universidade de Campinas (UNICAMP), Campinas, SP, Brazil.
    Objective: To evaluate surgical treatment of chronic atrial fibrillation with ultrasound in patients with mitral valve disease, considering preoperative clinical characteristics of patients undergoing surgical procedure and follow-up in the immediate postoperative period, in hospital and up to 60 months after discharge.

    Methods:: We studied 100 patients with chronic atrial fibrillation and mitral valve disease who underwent surgical treatment using ultrasound ablation. Patient data were reviewed by consulting the control reports, including signs and symptoms, underlying disease, functional class, hospital stay, surgical procedure time, ablation time, immediate complications, and complications at discharged and up to 60 months later. Read More

    Colchicine Improves Survival, Left Ventricular Remodeling, and Chronic Cardiac Function After Acute Myocardial Infarction.
    Circ J 2017 Jul 18;81(8):1174-1182. Epub 2017 Apr 18.
    Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University.
    Background: Several studies have reported that colchicine attenuated the infarct size and inflammation in acute myocardial infarction (MI). However, the sustained benefit of colchicine administration on survival and cardiac function after MI is unknown. It was hypothesized that the short-term treatment with colchicine could improve survival and cardiac function during the recovery phase of MI. Read More

    Misses Opportunity: TOF Diagnoses in 4th Decade of Life.
    J La State Med Soc 2017 Mar-Apr;169(2):54. Epub 2017 Apr 15.
    Department of Internal Medicine, LSU Health, Baton Rouge, LA.
    Case: A 40 year old woman with a history of HIV, congestive heart failure secondary to an unknown congenital heart defect, and hypertension presented to our emergency department with worsening edema. On room air, oxygen saturation was 55 percent . On 5L of oxygen via nasal cannula, oxygen saturation was 88 percent . Read More

    Three's a Crowd - An Extremely Rare Case of Cor Triatriatum Dexter.
    J La State Med Soc 2017 Mar-Apr;169(2):50-51. Epub 2017 Apr 15.
    Department of Medicine, Leonard J. Chabert Medical Center in Houma, LA.
    Introduction: Cor triatriatum is a congenital cardiac anomaly in which the left (sinister) or right (dexter) atrium is divided into two compartments by residual embryonic tissue, resulting in a tri-atrial heart. As cor triatriatum dextrum can present clinically in various ways and have multiple associated cardiac anomalies, this report attempts to contribute to what is known about this exceedingly rare disorder.

    Case: A 40 year old Hispanic man with a medical history of gastritis presented with complaints of palpitations, dizziness and bilateral lower extremity edema. Read More

    Paediatric-onset coronary artery anomalies in pregnancy: a single-centre experience and systematic literature review.
    Cardiol Young 2017 Oct 17;27(8):1529-1537. Epub 2017 Apr 17.
    1Toronto Congenital Cardiac Centre for Adults,Toronto General Hospital,University of Toronto,Toronto,Ontario,Canada.
    Objectives: Individuals with childhood-onset coronary artery anomalies are at increased risk of lifelong complications. Although pregnancy is thought to confer additional risk, a few data are available regarding outcomes in this group of women. We sought to define outcomes of pregnancy in this unique population. Read More

    A rare complication of viper envenomation: cardiac failure. A case report.
    Med Sante Trop 2017 Feb;27(1):52-55
    Service de réanimation médicale, CHU Habib-Bourguiba 3029 Sfax Tunisie.
    Viper envenomation is common in North Africa. Cardiac complications are not common features of snakebites, the clinical picture of which is usually dominated by toxin-associated neurological, hematological, and vascular damage. There are rare reports of acute myocardial infarction and/or ischemia caused by snakebites, while myocarditis after envenomation has not yet been reported, to our knowledge. Read More

    Assessment of Lung Ultrasound B-Lines in Dogs with Different Stages of Chronic Valvular Heart Disease.
    J Vet Intern Med 2017 May 29;31(3):700-704. Epub 2017 Mar 29.
    Department of Veterinary Sciences, University of Pisa, Pisa, Italy.
    Background: In dogs with chronic valvular heart disease (CVHD), early recognition of pulmonary edema (PE) is of paramount importance. Recent studies in dogs showed that lung ultrasound examination (LUS) is a useful technique to diagnose cardiogenic PE.

    Objectives: To describe LUS features in dogs with different stages of CVHD, and to determine its diagnostic accuracy in detecting PE using thoracic radiography as the reference standard. Read More

    J Zoo Wildl Med 2017 Mar;48(1):179-188
    Acute signs associated with cardiovascular disease occurred in three pregnant okapi ( Okapia johnstoni ) during early to midgestation and progressed to congestive heart failure. Congestive heart failure was diagnosed antemortem using echocardiography and plasma cardiac troponin levels. Clinical signs included decreased activity, hyporexia, tachypnea, dyspnea, flared nostrils, and productive coughing with copious amounts of foamy nasal discharge. Read More

    New pharmacological and technological management strategies in heart failure.
    Vasc Health Risk Manag 2017 21;13:111-121. Epub 2017 Mar 21.
    Division of Cardiovascular Medicine, Center for Advanced Heart Disease, Brigham and Women's Hospital, Boston, MA, USA.
    Heart failure is a complex clinical syndrome resulting from impairment of ventricular filling or ejection of blood associated with symptoms of dyspnea, fatigue, as well as peripheral and/or pulmonary edema. This syndrome is progressive and characterized by worsening quality of life despite escalating levels of care, affecting 5.7 million Americans with an annual cost of over ≥30 billion US dollars. Read More

    Atypical Complications of Graves' Disease: A Case Report and Literature Review.
    Case Rep Endocrinol 2017 28;2017:6087135. Epub 2017 Feb 28.
    Endocrine Department, Hamad Medical Corporation, Doha, P.O. Box 3050, Qatar.
    Graves' disease (GD) may display uncommon manifestations. We report a patient with rare complications of GD and present a comprehensive literature review. A 35-year-old woman presented with a two-week history of dyspnea, palpitations, and edema. Read More

    An unusual case of sudden unexpected death due to massive hemopericardium from primary mediastinal seminoma.
    Forensic Sci Int 2017 Jan 14;270:e1-e4. Epub 2016 Oct 14.
    Department of Pathology, Faculty of Medicine, Chiang Mai University, 110 Intawaroros Rd., Sribhoom, Chiang Mai 50200, Thailand. Electronic address:
    It is well-known that cardiovascular disease is the most common cause of sudden unexpected death, especially in the young. However complete postmortem investigation performed by qualified forensic pathologists is crucial in establishing the exact cause and manner of death. Sudden death caused by a cardiac tamponade occurring secondarily to a primary mediastinal tumor is extremely unusual. Read More

    Renal Artery Stenosis: When to Revascularize in 2017.
    Curr Probl Cardiol 2017 Apr 20;42(4):110-135. Epub 2017 Jan 20.
    Atherosclerotic renal artery stenosis is the leading cause of secondary hypertension; it can also cause progressive renal insufficiency and cardiovascular complications such as refractory heart failure and flash pulmonary edema. Medical therapy including risk factor modification, renin-angiotensin-aldosterone system antagonists, lipid lowering agents, and antiplatelet therapy is the first line of treatment in all patients. Patients with uncontrolled renovascular hypertension despite optimal medical therapy, ischemic nephropathy, and cardiac destabilization syndromes who have severe renal artery stenosis are likely to benefit from renal artery revascularization. Read More

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