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    3548 results match your criteria Congestive Heart Failure and Pulmonary Edema

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    Identification, Associated Factors, and Prognosis of Symptom Clusters in Taiwanese Patients With Heart Failure.
    J Nurs Res 2017 Feb 17. Epub 2017 Feb 17.
    1RN, PhD, Associate Professor, Department of Nursing, Chang Gung University of Science and Technology, Taoyuan, Taiwan, ROC 2RN, PhD, FAAN, Professor, College of Nursing, University of Kentucky, Lexington, USA 3RN, DNSc, Chair Professor, Department of Nursing, Asia University, Taichung, Taiwan, ROC.
    Background: Patients with heart failure (HF) have multiple distressing symptoms that are associated with poor outcomes. These symptoms do not occur in isolation from each other but likely occur as discrete clusters that may prove helpful to clinicians trying to counsel patients about symptom monitoring and management. Defining common symptom clusters and determining the associations between symptom clusters and outcomes may improve patient management. Read More

    Hydrogen sulfide reduces recruitment of CD11b(+)Gr-1(+) cells in mice with myocardial infarction.
    Cell Transplant 2017 Feb 9. Epub 2017 Feb 9.
    Institute of Clinical Medicine and Department of Cardiology, Renmin Hospital, Hubei University of Medicine, Shiyan, China.
    The present study aimed to elucidate the mechanisms by which hydrogen sulfide (H2S) attenuates left ventricular remodeling after MI. Myocardial infarction was created in mice by left coronary artery ligation. One group of mice received injections of the H2S donor sodium hydrosulfide (NaSH) immediately before and one hour after ligation, while the control group received saline alone. Read More

    Fluctuation of Dynamic Diastolic Function Relative to Static Cardiac Structure - New Insights Into the Underlying Mechanism of Heart Failure With Preserved Ejection Fraction in Elderly Patients.
    Circ J 2017 Jan 28. Epub 2017 Jan 28.
    Department of Cardiovascular Medicine, Yao Municipal Hospital.
    Background: The mechanisms of heart failure with preserved ejection fraction (HFpEF) need to be clarified immediately.Methods and Results:We examined diastolic function relative to arterial elasticity among hypertensive patients with preserved EF. Diastolic elastance (EdI)/effective arterial elastance (EaI), EdI/EaI=E/e'/(0. Read More

    Respiratory Muscle Training Improves Chemoreflex Response, Heart Rate Variability, and Respiratory Mechanics in Rats With Heart Failure.
    Can J Cardiol 2016 Nov 11. Epub 2016 Nov 11.
    Post Graduation Program in Health Sciences, Laboratory of Experimental Physiology, Federal University of Health Sciences of Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil; Post Graduation Program in Rehabilitation Sciences, Federal University of Health Sciences of Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil. Electronic address:
    Background: The aim of the present report was to evaluate respiratory muscle training (RMT) effects on hemodynamic function, chemoreflex response, heart rate variability, and respiratory mechanics in rats with heart failure (HF rats).

    Methods: Wistar rats were divided into 4 groups: sedentary-sham (Sed-Sham, n = 8), respiratory muscle trained-sham (RMT-Sham, n = 8), sedentary-HF (Sed-HF, n = 8) and respiratory muscle trained-HF (RMT-HF, n = 8). Animals were submitted to an RMT protocol performed 30 minutes per day, 5 days per week for 6 weeks, whereas the sedentary animals did not exercise. Read More

    Who Needs Longer Tolvaptan Treatment?
    Int Heart J 2017 Feb 20;58(1):30-35. Epub 2017 Jan 20.
    Second Department of Internal Medicine, University of Toyama.
    The vasopressin receptor 2 (V2) receptor antagonist tolvaptan is an aquaretic agent that has been approved for heart failure patients with volume overload in Japan. In this study (SMILE study), we investigated patient characteristics and effectiveness in both a 14 days and shorter treated group (14DS) and 15 days and longer treated group (15DL). The results showed that the patients in the 15DL group had low cardiac output with intensive diuretic administration (ie, diuretic resistance). Read More

    Acute kidney injury as an independent risk factor for unplanned 90-day hospital readmissions.
    BMC Nephrol 2017 Jan 6;18(1). Epub 2017 Jan 6.
    University of Aberdeen, Institute of Applied Health Sciences, Aberdeen, UK.
    Background: Reducing readmissions is an international priority in healthcare. Acute kidney injury (AKI) is common, serious and also a global concern. This analysis evaluates AKI as a candidate risk factor for unplanned readmissions and determines the reasons for readmissions. Read More

    A retrospective study of degenerative mitral valve disease in small-breed dogs: Survival and prognostic variables.
    J Vet Sci 2017 Jan 4. Epub 2017 Jan 4.
    Department of Veterinary Internal Medicine, College of Veterinary Medicine, Seoul National University, Seoul 08826, Korea.
    Small-breed (n= 168 dogs; weight < 15 kg) diagnosed with MMVD based on a routine clinical examination, radiology, an electrocardiogram, and echocardiography at the Seoul National University Veterinary Medical Teaching Hospital were included. The survival periods were ascertained and a significant difference was observed in the survival rates between the International Small Animal Cardiac Health Council classes. The mean follow-up period was 14. Read More

    Visceral and tissular reactivity in acute heart failure due to supraventricular tachyarrhythmia in a young patient.
    Rom J Morphol Embryol 2016 ;57(3):1099-1105
    Department of Internal Medicine, University of Medicine and Pharmacy of Craiova, Romania;
    Observation of major pathological alterations in a young person involves etiological and clinical justifications, in order to properly assess, treat and control these conditions. The aim of this paper is to present severe, acute pathological lesions, installed in a young person, secondary to hypodiastolic heart failure, due to persistent supraventricular tachyarrhythmia, triggered by a post-traumatic external stimulus, with complete remission post-electrical conversion. Pathological and clinical modification are revealed, in a young person, shortly after a minor thoracic trauma, in the absence of traumatic injury but with high-frequency palpitations onset and progressive installation of vascular, visceral and interstitial stasis modifications, as well as of vascular and tissular hypoperfusion with reactive vasoconstriction. Read More

    Pulmonary Complications After Open Abdominal Aortic Surgery: A Systematic Review and Meta-Analysis.
    J Cardiothorac Vasc Anesth 2016 Oct 1. Epub 2016 Oct 1.
    Departments of Anesthesia and Intensive Care.
    Objectives: Postoperative pulmonary complications (PPC) are among the most common complications after noncardiac surgery. Men, smokers, and elderly patients with chronic obstructive pulmonary disease or heart failure are more likely to experience PPC. The majority of patients undergoing vascular surgery belong in these categories and are at higher risk of developing PPC. Read More

    [Patient-related independent clinical risk factors for early complications following interventional pulmonology procedures].
    Beijing Da Xue Xue Bao 2016 Dec;48(6):1006-1011
    Department of Respiratory and Critical Care Medicine, Peking University First Hospital, Beijing 100034, China.
    Objective: To investigate the early complication rate and identify patient-related independent clinical risk factors for early complications in patients following interventional pulmonology procedures.

    Methods: In the period from December 2014 to December 2015, sufficient data of Peking University First Hospital Respiratory and Critical Care Medicine Department for analysis were identified in 218 subjects. Interventional pulmonology procedures were performed in all the patients. Read More

    Echocardiography findings in a case with Ballantyne syndrome.
    J Obstet Gynaecol Res 2017 Feb 17;43(2):387-391. Epub 2016 Dec 17.
    Department of Obstetrics, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
    Marked fluid retention occurs in Ballantyne syndrome, but few reports are available on changes in cardiac morphology in this syndrome. A woman with generalized edema, dyspnea, fetal hydrops (skin edema and ascites), thickened placenta, and elevated plasma B-type natriuretic peptide level (344 pg/mL) was admitted to our hospital at gestational week (GW) 20(+3) . Blood pressure remained within the normal range. Read More

    The importance of proteinuria and prior cardiovascular disease in all major clinical outcomes of atherosclerotic renovascular disease - a single-center observational study.
    BMC Nephrol 2016 Dec 7;17(1):198. Epub 2016 Dec 7.
    Department of Renal Medicine, Salford Royal NHS Foundation Trust, Salford, M6 8HD, United Kingdom.
    Background: Identification of patients at risk of developing adverse events would enable aggressive medical therapy and possibly targeted revascularization. The aim of this study is to characterize the determinants of long-term outcomes in atherosclerotic renovascular disease (ARVD).

    Methods: Patients with a radiological diagnosis of ARVD were recruited into this single-center prospective cohort study between 1986 and 2014. Read More

    Association of Biomarkers with Serious Cardiac Adverse Events during Abiraterone Acetate Treatment in Castration Resistant Prostate Cancer.
    Transl Oncol 2016 Dec;9(6):600-605
    Units of Medical Oncology, E.O. Ospedali Galliera, Genova, Italy.
    Background: Abiraterone acetate is an effective drug for castration-resistant prostate cancer, but cardiac serious adverse events (SAEs) may occur. We studied their association with N-terminal pro-brain natriuretic peptide (NT-proBNP) and troponin T (TnT) during abiraterone therapy.

    Patients And Methods: In a single institution, 17 patients were treated with abiraterone acetate 1 g daily with concomitant prednisone and then switched to dexametasone plus canrenone. Read More

    Pharmacokinetic study of furosemide incorporated PLGA microspheres after oral administration to rat.
    Iran J Basic Med Sci 2016 Oct;19(10):1049-1055
    Department of Pharmacology and Toxicology, School of Pharmacy, Kermanshah University of Medical Sciences, Kermanshah.
    Objectives: The purpose of the current study was to assess the feasibility of microspheres from biocompatible polymer for oral bioavailability (BA) enhancement of potent sulfonamide- type loop diuretic- Furosemide - which used in the treatment of congestive heart failure, caused edema, cirrhosis, renal disease and as an adjunct in acute pulmonary edema. The comparatively poor and inconstant BA of furosemide, which occurs site-specifically in the stomach and upper small intestine, has been ascribed to the poor dissolution of furosemide.

    Materials And Methods: In attempt to enhance the drug BA, poly (dl-lactic-co-glycolic acid) (PLGA) microspheres of furosemide were obtained using solvent-evaporation method and the carrier characteristics were investigated subsequently. Read More

    Effect of β2-adrenergic receptor stimulation on lung fluid in stable heart failure patients.
    J Heart Lung Transplant 2016 Oct 2. Epub 2016 Oct 2.
    Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
    Background: The purpose of this study was to determine: (1) whether stable heart failure patients with reduced ejection fraction (HFrEF) have elevated extravascular lung water (EVLW) when compared with healthy control subjects; and (2) the effect of acute β2-adrenergic receptor (β2AR) agonist inhalation on lung fluid balance.

    Methods: Twenty-two stable HFrEF patients and 18 age- and gender-matched healthy subjects were studied. Lung diffusing capacity for carbon monoxide (DLCO), alveolar-capillary membrane conductance (DmCO), pulmonary capillary blood volume (Vc) (via re-breathe) and lung tissue volume (Vtis) (via computed tomography) were assessed before and within 30 minutes after administration of nebulized albuterol. Read More

    Cardiac dysfunction induced by weaning from mechanical ventilation: incidence, risk factors, and effects of fluid removal.
    Crit Care 2016 Nov 12;20(1):369. Epub 2016 Nov 12.
    Université Paris-Sud, Faculté de Médecine, Université Paris-Saclay, Le Kremlin-Bicêtre, France.
    Background: Weaning-induced pulmonary oedema (WiPO) is a well-recognised cause of failure of weaning from mechanical ventilation, but its incidence and risk factors have not been reliably described. We wanted to determine the incidence and risk factors in a population of critically ill patients. In addition, we wanted to describe the effects of diuretics when they are administered in this context. Read More

    Identification of volume overload hospitalizations among hemodialysis patients using administrative claims: a validation study.
    BMC Nephrol 2016 Nov 11;17(1):173. Epub 2016 Nov 11.
    Division of Nephrology and Hypertension, Department of Medicine, University of North Carolina Kidney Center, UNC School of Medicine, 7024 Burnett-Womack CB #7155, Chapel Hill, NC, 27599-7155, USA.
    Background: High rates of volume overload hospitalizations may indicate inadequate dialysis facility fluid management. Administrative claims databases are often used to study such outcomes, but these data are generated for billing purposes and may not capture clinical nuance. It is unknown if volume overload admissions can be correctly identified in administrative data and if a single claims-based definition for volume overload can be used across epidemiologic surveillance studies, observational studies of exposure-outcome associations and quality assessments. Read More

    Delayed High Output Heart Failure due to Arteriovenous Fistula Complicated with Herniated Disc Surgery.
    J Korean Med Sci 2016 Dec;31(12):2051-2053
    Department of Internal Medicine, Weiss Memorial Hospital, Chicago, IL, USA.
    A 36-year-old male presented with progressive exertional dyspnea over months. Physical examination showed jugular venous distension, lung crecipitations, femoral bruit and pitting pedal edema. Echocardiogram showed a dilated right ventricle with severe pulmonary hypertension and a non collapsing inferior vena cava (IVC). Read More

    Isolated Left Ventricular Apical Hypoplasia: Reporting a Case With Mild Manifestations and Different Echocardiography Features.
    Iran Red Crescent Med J 2016 Aug 16;18(8):e26065. Epub 2016 Jul 16.
    Isfahan University of Medical Sciences, Isfahan, IR Iran.
    Introduction: Isolated left ventricular apical hypoplasia is an unusual type of cardiomyopathy that presents with different clinical manifestations according to the age of the disease, ranging from no symptoms in children to congestive heart failure, pulmonary edema, or even malignant tachycardia in adults. To our knowledge, only a few cases of isolated left ventricular apical hypoplasia have been reported in Asian adults.

    Case Presentation: Herein, we described an adult case of isolated left ventricular apical hypoplasia referred to our heart center in Isfahan, Iran in 2015 with a complaint of mild dyspnea with the absence of obvious fatty tissue in the heart's apex and an absence of any shunt, which are common findings in patients with this phenomenon. Read More

    ECG Case of the Month: Heart Failure in a Man from Chile.
    J La State Med Soc 2016 Sep-Oct;168(5):180-181. Epub 2016 Oct 15.
    Department of Medicine at Louisiana State University Health Sciences Center in New Orleans, LA.
    A 49-year-old man visiting New Orleans from Chile comes to the hospital complaining of exertional dyspnea for 2 months with the more recent onset of ankle edema. He is a slender man with a blood pressure of 91/60 mmHg, crackles at both lung bases, and markedly distended neck veins. His cardiac rhythm is irregular. Read More

    In vitro performance investigation of SynCardia™ Freedom® driver via patient simulator mock loop.
    Int J Artif Organs 2016 Nov 15;39(10):502-508. Epub 2016 Oct 15.
    Cardiovascular Fluid Dynamics Laboratory HER, Department of Civil, Environmental and Architectural Engineering - DICEA, University of Padua, Padua - Italy.
    Purpose: The gold standard therapy for patients with advanced heart failure is heart transplant. The gap between donors and patients in waiting lists promoted the development of circulatory support devices, such as the total artificial heart (TAH). Focusing on in vitro tests performed with CardioWest™ TAH (CW) driven by the SynCardia Freedom® portable driver (FD) the present study goals are: i) prove the reliability of a hydraulic circuit used as patient simulator to replicate a quasi-physiological scenario for various hydrodynamic conditions, ii) investigate the hydrodynamic performance of the CW FD, iii) help clinicians in possible interpretation of clinical cases outcomes. Read More

    Tetralogy of Fallot and pheochromocytoma in a situs inversus totalis: An unusual association.
    J Cardiovasc Thorac Res 2016 30;8(3):132-136. Epub 2016 Sep 30.
    Hospital Nacional Arzobispo Loayza, Lima, Perú ; Universidad Nacional Federico Villarreal, Facultad de Medicina, Lima, Perú.
    Introduction: Situs inversus totalis is an uncommon anomaly which exist a complete transposition of organs and it's occasionally associated with congenital heart diseases, such as tetralogy of fallot. Pheochromocytoma is a rare neuroendocrine tumor with an annual incidence of 2-8 cases per million people and for years has been studied its relationship with the hypoxic pathway. Case Report: A 29 year old male with a history of tetralogy of fallot corrected at 10 years and situs inversus totalis. Read More

    Classification and Prognostic Evaluation of Left Ventricular Remodeling in Patients With Asymptomatic Heart Failure.
    Am J Cardiol 2017 Jan 29;119(1):71-77. Epub 2016 Sep 29.
    Dipartimento di Patologia Medica, Chirurgica, Molecolare e dell'Area Critica, Università di Pisa, Italy.
    Patients with asymptomatic heart failure (HF; stage A and B) are characterized by maladaptive left ventricular (LV) remodeling. Classic 4-group classification of remodeling considers only LV mass index and relative wall thickness as variables. Complex remodeling classification (CRC) includes also LV end-diastolic volume index. Read More

    Diastolic dysfunction in the critically ill patient.
    Med Intensiva 2016 Nov 25;40(8):499-510. Epub 2016 Aug 25.
    Servicio de Medicina Intensiva, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Calle de Sant Quintí, 89, 08026 Barcelona, Spain. Electronic address:
    Left ventricular diastolic dysfunction is a common finding in critically ill patients. It is characterized by a progressive deterioration of the relaxation and the compliance of the left ventricle. Two-dimensional and Doppler echocardiography is a cornerstone in its diagnosis. Read More

    Serious maternal complications in relation to severe pre-eclampsia: a retrospective cohort study of the impact of hospital volume.
    BJOG 2016 Oct 21. Epub 2016 Oct 21.
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
    Objective: We examined rates of serious maternal complications in relation to severe pre-eclampsia based on the delivering hospital's annualised volume.

    Design: Retrospective cohort study.

    Population And Setting: Singleton deliveries (n = 25 782 235) in 439 hospitals in the USA. Read More

    Congestive Adenopathy: A Mediastinal Sequela of Volume Overload.
    J Bronchology Interv Pulmonol 2016 Oct;23(4):298-302
    *Department of Internal Medicine, Division of Pulmonary and Critical Care †Department of Internal Medicine, Marshall University, Huntington, WV ‡Department of Internal Medicine, Pulmonary and Critical Care, Interventional Pulmonary, University of Arkansas for Medical Sciences, Little Rock, AR.
    Background: Endosonography has improved our ability to reach thoracic lymph nodes and to diagnose pathologic conditions with nodal involvement and has lowered the threshold for biopsy. The purpose of this study was to avoid unnecessary procedures, it is important to recognize benign adenopathy. Congestive heart failure (CHF) is both common and a common cause of adenopathy. Read More

    Exercise training effects on elderly and middle-age patients with chronic heart failure after acute decompensation: A randomized, controlled trial.
    Int J Cardiol 2016 Dec 11;225:313-323. Epub 2016 Oct 11.
    Section of Cardiovascular Diseases, Department of Emergency and Organ Transplantation, University of Bari, School of Medicine, Bari, Italy. Electronic address:
    Background: The aim of this study was to evaluate the effect of exercise training on cardiac function in heart failure (HF) patients recently suffering from acute decompensation. Radionuclide ambulatory ventricular function monitoring (VEST) was used to detect variations in cardiac hemodynamics during training period.

    Methods: This was a monocentric, randomized, controlled trial. Read More

    Goal directed fluid therapy decreases postoperative morbidity but not mortality in major non-cardiac surgery: a meta-analysis and trial sequential analysis of randomized controlled trials.
    J Anesth 2017 Feb 13;31(1):66-81. Epub 2016 Oct 13.
    Department of Anaesthesiology, Pain Medicine and Critical Care, All India Institute of Medical Sciences, New Delhi, 110029, India.
    Background And Aims: Optimum perioperative fluid administration may improve postoperative outcome after major surgery. This meta-analysis and systematic review has been aimed to determine the effect of dynamic goal directed fluid therapy (GDFT) on postoperative morbidity and mortality in non-cardiac surgical patients.

    Material And Methods: Meta-analysis of published prospective randomized controlled trials where GDFT based on non-invasive flow based hemodynamic measurement has been compared with a standard care. Read More

    Prognostic Importance of Exercise Brain Natriuretic Peptide in Asymptomatic Chronic Organic Severe Mitral Regurgitation: An Observational Study.
    J Clin Med Res 2016 Nov 29;8(11):797-804. Epub 2016 Sep 29.
    Department of Cardiology, LPS Institute of Cardiology, G. S. V. M. Medical College, Kanpur, Uttar Pradesh 208002, India.
    Background: The optimal timing of surgery in patients with chronic organic severe mitral regurgitation (MR) continues to be debated, especially for those who are asymptomatic. The aim of the study was to determine independent and additive prognostic value of exercise brain natriuretic peptide (eBNP) in patients with severe asymptomatic MR and normal left ventricular ejection fraction (LVEF).

    Methods: Two hundred twenty-three consecutive patients with severe MR defined by effective regurgitant orifice (ERO) area ≥ 40 mm(2) and/or residual volume ≥ 60 mL, LVEF > 60%, and normal LV end-systolic diameter < 40 mm underwent symptom limited exercise treadmill test (TMT). Read More

    Clinical and prognostic correlates of pulmonary congestion in coronary computed tomography angiography data sets.
    J Cardiovasc Comput Tomogr 2016 Nov - Dec;10(6):466-472. Epub 2016 Sep 15.
    Department of Cardiology, The Heart Centre, Rigshospitalet, University of Copenhagen, Denmark; Department of Radiology, Diagnostic Centre, Rigshospitalet, University of Copenhagen, Denmark.
    Background: Signs of pulmonary congestion obtained from cardiac computed tomography angiographic (coronary CTA) images have not previously been related to clinical congestion or outcome and the clinical value is, therefore, unknown. Our objective was to test the hypothesis that signs of pulmonary congestion predict clinical heart failure and adverse outcome in patients with myocardial infarction.

    Methods: Coronary CTA was performed before invasive treatment in 400 prospectively included patients with non ST segment elevation myocardial infarction in an observational study. Read More

    Biventricular transient systolic dysfunction after mitral valve replacement: Pericardial decompression syndrome.
    Int J Surg Case Rep 2016 30;28:145-148. Epub 2016 Sep 30.
    Department of Cardiovascular Surgery, Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey.
    Background: Pericardial decompression syndrome is defined as paradoxical hemodynamic instability, left ventricular or bi ventricular systolic dysfunction and pulmonary edema after pericardial fluid drainage. Pericardial Decompression Syndrome is an unexpected clinical scenario with an incidence less than 5% in all surgically or percutaneously managed pericardial tamponade patients. The aim of this manuscript was to describe a case with cardiac tamponade in whom acute biventricular heart failure and pulmonary edema developed after surgical creation of a pericardial window, and to discuss this case in light of the literature. Read More

    Triple threat in pregnancy.
    BMJ Case Rep 2016 Oct 4;2016. Epub 2016 Oct 4.
    Department of Cardiovascular Medicine, Allegheny Health Network, Pittsburgh, Pennsylvania, USA.
    A woman aged 22 years with a history of lupus presented in the 18th week of pregnancy with hypertensive emergency and flash pulmonary oedema. Bedside echocardiogram revealed severe left ventricular (LV) dysfunction with an ejection fraction (EF) of 25% and pericardial effusion. Laboratories revealed hypocomplementemia, proteinuria, elevated C reactive protein and anti-DS-DNA, raising concern for a lupus flare. Read More

    Role of PiCCO monitoring for the integrated management of neurogenic pulmonary edema following traumatic brain injury: A case report and literature review.
    Exp Ther Med 2016 Oct 23;12(4):2341-2347. Epub 2016 Aug 23.
    General Intensive Care Unit, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310009, P.R. China.
    Neurogenic pulmonary edema (NPE) is occasionally observed in patients with traumatic brain injury (TBI); however, this condition is often underappreciated. NPE is frequently misdiagnosed due to its atypical clinical performance, thus delaying appropriate treatment. A comprehensive management protocol of NPE in patients with TBI has yet to be established. Read More

    [Measurement of fractional flow reserve in patients with severe aortic stenosis: A valid test?]
    Ann Cardiol Angeiol (Paris) 2016 Nov 28;65(5):366-369. Epub 2016 Sep 28.
    Service de cardiologie, centre hospitalier intercommunal Le Raincy Montfermeil, rue du Général-Leclerc, 93370 Montfermeil, France. Electronic address:
    A 54-year-old woman was hospitalized for an acute pulmonary oedema revealing a severe aortic stenosis (AS) associated with an aortic aneurysm and a left ventricular hypertrophy (LVH). The coronary angiography found an equivocal left main lesion. Fractional flow reserve (FFR) showed hemodynamic significance (FFR=0. Read More

    A case of recent myocardial infarction with cardiac failure.
    Heart 2016 Sep 29. Epub 2016 Sep 29.
    Department of Cardiology, Government Medical College, Kozhikode, Kerala, India.
    Clinical Introduction: A 50-year-old hypertensive smoker presented with a typical angina of 2 days duration. An urgent ECG revealed extensive anterior wall myocardial infarction. In view of the delayed presentation, the patient was conservatively managed with heparin. Read More

    Cardiogenic Pulmonary Edema in a Dog Following Initiation of Therapy for Concurrent Hypoadrenocorticism and Hypothyroidism.
    J Am Anim Hosp Assoc 2016 Nov/Dec;52(6):378-384. Epub 2016 Sep 29.
    From the Chungbuk National University College of Veterinary Medicine, Cheongju, South Korea.
    A 5 yr old intact female cocker spaniel dog weighing 7.8 kg was referred with anorexia, vomiting, and depression. At referral, the dog was diagnosed initially with typical hypoadrenocorticism, and 2 d later, concurrent primary hypothyroidism was detected. Read More

    Physiological mechanisms of pulmonary hypertension.
    Am Heart J 2016 Oct 15;180:1-11. Epub 2016 Jul 15.
    Biological Physics Group, School of Physics & Astronomy, University of Manchester, Manchester, United Kingdom.
    Pulmonary hypertension is usually related to obstruction of pulmonary blood flow at the level of the pulmonary arteries (eg, pulmonary embolus), pulmonary arterioles (idiopathic pulmonary hypertension), pulmonary veins (pulmonary venoocclusive disease) or mitral valve (mitral stenosis and regurgitation). Pulmonary hypertension is also observed in heart failure due to left ventricle myocardial diseases regardless of the ejection fraction. Pulmonary hypertension is often regarded as a passive response to the obstruction to pulmonary flow. Read More

    Maternal Cardiac Diastolic Dysfunction by Doppler Echocardiography in Women with Preeclampsia.
    J Clin Diagn Res 2016 Aug 1;10(8):QC01-3. Epub 2016 Aug 1.
    Professor, Department of Obstetrics and Gynaecology, Postgraduate Institute of Medical Education and Research , Chandigarh, India .
    Introduction: Preeclampsia may lead to heart failure in late pregnancy and early puerperium. Diastolic dysfunction may be the cause of heart failure in these patients. There is paucity of data on diastolic dysfunction in patients with preeclampsia. Read More

    Efficacy of pimobendan on survival and reoccurrence of pulmonary edema in canine congestive heart failure.
    J Vet Med Sci 2017 Jan 17;79(1):29-34. Epub 2016 Sep 17.
    Japan Animal Specialty Medical Institute Inc., JASMINE Veterinary Cardiovascular Medical Center, 2-7-3 Nakagawa, Tsuzuki, Yokohama, Kanagawa 224-0001, Japan.
    The aim of this study was to evaluate the efficacy of pimobendan with conventional therapies on survival and reocurrence of pulmonary edema in dogs with congestive heart failure (CHF) caused by myxomatous mitral valve disease (MMVD). Records of 197 client-owned dogs from 14 veterinary hospitals were included in this study. Dogs were administered conventional treatments with or without pimobendan. Read More

    Eclipsed mitral regurgitation: an unusual cause of acute heart failure.
    Eur Heart J Cardiovasc Imaging 2016 Sep 13. Epub 2016 Sep 13.
    Department of Cardiology, Assistance Publique-Hôpitaux de Paris, Bichat Hospital, 46 Rue Henri Huchard, 75018 Paris, France DHU Fire, Paris-Diderot University, Paris, France INSERM U1148 Bichat Hospital, Paris, France Faculté de Médecine Paris-Diderot University, Paris, France.
    Aims: So far, a total of five patients with eclipsed mitral regurgitation (MR) have been reported in the literature by three different teams. The aim of this article was to detail clinical and echocardiographic characteristics, and outcome of patients presenting eclipsed MR.

    Methods And Results: We defined eclipsed MR as spontaneous appearance, at rest, from 1 min to the next of an acute restriction in the motion of mitral leaflets preventing coaptation and leading to massive MR in patients with normal left ventricular end-diastolic diameter, left ventricular ejection fraction >45%, and baseline MR ≤2. Read More

    Carbonic anhydrase inhibitors reduce cardiac dysfunction after sustained coronary artery ligation in rats.
    Cardiovasc Pathol 2016 Nov - Dec;25(6):468-477. Epub 2016 Aug 21.
    Centro de Investigaciones Cardiovasculares, Consejo Nacional de Investigaciones Científicas y Técnicas, Facultad de Ciencias Médicas, Universidad Nacional de La Plata, 1900 La Plata, Buenos Aires, Argentina. Electronic address:
    Background: Two potent carbonic anhydrase (CA) inhibitors with widely differing membrane permeability, poorly diffusible benzolamide (BZ), and highly diffusible ethoxzolamide (ETZ) were assessed to determine whether they can reduce cardiac dysfunction in rats subjected to coronary artery ligation (CAL)-induced myocardial infarction.

    Methods And Results: Rats with evidence of heart failure (HF) at 32 weeks following a permanent left anterior coronary artery occlusion were treated with placebo, BZ, or ETZ (4 mg kgday(-1)) for 4 weeks at which time left ventricular function and structure were evaluated. Lung weight/body weight (LW/BW) ratio increased in CAL rats by 17±1% vs. Read More

    Development of a clinical prediction score for congestive heart failure diagnosis in the emergency care setting: The Brest score.
    Am J Emerg Med 2016 Dec 14;34(12):2277-2283. Epub 2016 Aug 14.
    Urgences adultes, CHRU de la Cavale Blanche, Bvd Tanguy-Prigent, 29609 Brest Cedex, France; Réanimation Médicale, CHRU de la Cavale Blanche, Bvd Tanguy-Prigent, 29609 Brest Cedex, France; LATIM, INSERM UMR 1101, Université de Bretagne Occidentale, 29200 Brest, France. Electronic address:
    Objective: To derive and validate a clinical prediction rule of acute congestive heart failure obtainable in the emergency care setting.

    Design: Derivation of the score was performed on a retrospective 927 patients cohort admitted to our Emergency Department for dyspnea. The prediction model was externally validated on an independent 206-patient prospective cohort. Read More

    Scrub typhus infection presenting as acute heart failure: A case report and systematic review of literature of cardiopulmonary involvement in scrub typhus infection.
    Lung India 2016 Jul-Aug;33(4):439-43
    Department of Pulmonary Critical Care and Sleep Medicine, Fortis Flt Lt Rajan Dhall Hospital, New Delhi, India.
    We describe a middle aged previoulsy healthy female patient who presented with clinical features suggestive of acute heart failure. Investigations revealed very high NT pro-BNP, right heart enlargement, bilateral pulmonary alveolar edema and bilateral pleural effusion. In view of falling platelet counts and exudative pleural effusion inflammatory/infective causes were considered. Read More

    Chronic heart failure modifies respiratory mechanics in rats: a randomized controlled trial.
    Braz J Phys Ther 2016 Jul-Aug;20(4):320-7. Epub 2016 Apr 8.
    Laboratório de Fisiologia Cardiovascular, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, RS, Brazil.
    Objective: To analyze respiratory mechanics and hemodynamic alterations in an experimental model of chronic heart failure (CHF) following myocardial infarction.

    Method: Twenty-seven male adult Wistar rats were randomized to CHF group (n=12) or Sham group (n=15). Ten weeks after coronary ligation or sham surgery, the animals were anesthetized and submitted to respiratory mechanics and hemodynamic measurements. Read More

    The Pathophysiology of Nitrogen Dioxide During Inhaled Nitric Oxide Therapy.
    ASAIO J 2017 Jan/Feb;63(1):7-13
    From the *Biomedical Research, GeNO LLC, Cocoa, Florida; and †Department of Cardiovascular and Thoracic Surgery, University of Louisville, Louisville, Kentucky.
    Administration of inhaled nitric oxide (NO) with the existing compressed gas delivery systems is associated with unavoidable codelivery of nitrogen dioxide (NO2), an unwanted toxic contaminant that forms when mixed with oxygen. The NO2 is generated when NO is diluted with O2-enriched air before delivery to the patient. When NO2 is inhaled by the patient, it oxidizes protective antioxidants within the epithelial lining fluid (ELF) and triggers extracellular damage in the airways. Read More

    Rev Prat 2016 Jun;66(6):608-10
    Cardiorenal syndromes refer to clinical and metabolic consequences of acute and chronic heart failure or kidney disease on other organ. Recent studies have further clarified the pathophysiological mechanisms behind the different types of cardiorenal syndromes and propose a new classification. The cardiorenal syndrome type 1 corresponds to an acute heart failure (cardiogenic shock, acute decompensated congestive heart failure) which induces acute renal dysfunction. Read More

    Pulmonary Edema and Hypoxic Respiratory Failure.
    Pediatr Crit Care Med 2016 Aug;17(8 Suppl 1):S178-81
    1Department of Pediatrics, Section of Critical Care Medicine, Duke University School of Medicine, Duke Children's Hospital and Health Center, Durham, NC. 2Department of Pediatrics, Section of Critical Care Medicine and Cardiology, Cardiac Intensive Care Unit, Duke University School of Medicine, Duke Children's Hospital and Health Center, Durham, NC.
    Objectives: The purpose of this chapter is to outline the causes, physiology, pathophysiology, and management strategies for hydrostatic and permeability pulmonary edema and hypoxic respiratory failure.

    Data Source: MEDLINE and PubMed.

    Conclusion: The pulmonary parenchyma and vasculature are at high risk in conditions where injury occurs to the lung and or heart. Read More

    [Treatment by bloodletting in the past and present].
    Srp Arh Celok Lek 2016 Mar-Apr;144(3-4):240-8
    Introduction: Therapeutic bloodletting has been practiced at least 3000 years as one of the most frequent methods of treatment in general, whose value was not questioned until the 19th century, when it was gradually abandoned in Western medicine, while it is still practiced in Arabic and traditional Chinese medicine.

    Content: In modern medicine bloodletting is practiced for very few indications. Its concept was modeled on the process of menstrual bleeding, for which it was believed to"purge women of bad humours. Read More

    Prehospital lung ultrasound for the diagnosis of cardiogenic pulmonary oedema: a pilot study.
    Scand J Trauma Resusc Emerg Med 2016 Aug 2;24:96. Epub 2016 Aug 2.
    Mobile Emergency Care Unit, Odense University Hospital, Odense, Denmark.
    Background: An improved prehospital diagnostic accuracy of cardiogenic pulmonary oedema could potentially improve initial treatment, triage, and outcome. A pilot study was conducted to assess the feasibility, time-use, and diagnostic accuracy of prehospital lung ultrasound (PLUS) for the diagnosis of cardiogenic pulmonary oedema.

    Methods: A prospective observational study was conducted in a prehospital setting. Read More

    Usefulness of the Sum of Pulmonary Capillary Wedge Pressure and Right Atrial Pressure as a Congestion Index that Prognosticates Heart Failure Survival (from the Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness Trial).
    Am J Cardiol 2016 Sep 28;118(6):854-9. Epub 2016 Jun 28.
    Section of Cardiology, Department of Medicine, Baylor College of Medicine and Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas; Winters Center for Heart Failure Research and Cardiovascular Research Institute, Baylor College of Medicine, Houston, Texas.
    In the Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness (ESCAPE) trial, use of a pulmonary artery catheter did not significantly affect advanced heart failure outcomes. However, the success of achieving the targeted hemodynamic goals of pulmonary capillary wedge pressure (PCWP) of 15 mm Hg and right atrial pressure (RAP) of 8 mm Hg and the association of these goals with clinical outcomes were not addressed. Furthermore, goals with 2 independent variables, PCWP and RAP, left room for uncertainties. Read More

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