33,174 results match your criteria Congestive Heart Failure Imaging


Correlates and Timing of Reproductive Aging Transitions in a Global Cohort of Midlife Women With Human Immunodeficiency Virus: Insights From the REPRIEVE Trial.

J Infect Dis 2020 Jul;222(Supplement_1):S20-S30

Metabolism Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.

Background: Reproductive aging may contribute to cardiometabolic comorbid conditions. We integrated data on gynecologic history with levels of an ovarian reserve marker (anti-müllerian hormone [AMH)] to interrogate reproductive aging patterns and associated factors among a subset of cisgender women with human immunodeficiency virus (WWH) enrolled in the REPRIEVE trial.

Methods: A total of 1449 WWH were classified as premenopausal (n = 482) (menses within 12 months; AMH level ≥20 pg/mL; group 1), premenopausal with reduced ovarian reserve (n = 224) (menses within 12 months; AMH <20 pg/mL; group 2), or postmenopausal (n = 743) (no menses within12 months; AMH <20 pg/mL; group 3). Read More

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http://dx.doi.org/10.1093/infdis/jiaa214DOI Listing

Myocardial Steatosis Among Antiretroviral Therapy-Treated People With Human Immunodeficiency Virus Participating in the REPRIEVE Trial.

J Infect Dis 2020 Jul;222(Supplement_1):S63-S69

Metabolism Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.

Background: People with human immunodeficiency virus (PWH) face increased risks for heart failure and adverse heart failure outcomes. Myocardial steatosis predisposes to diastolic dysfunction, a heart failure precursor. We aimed to characterize myocardial steatosis and associated potential risk factors among a subset of the Randomized Trial to Prevent Vascular Events in HIV (REPRIEVE) participants. Read More

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http://dx.doi.org/10.1093/infdis/jiaa245DOI Listing

Mitral regurgitation after transcatheter aortic valve replacement.

J Thorac Dis 2020 May;12(5):2926-2935

Department of Cardiovascular Surgery, Università Campus Bio-Medico di Roma, Rome, Italy.

Patients undergoing transcatheter aortic valve replacement (TAVR) might have an associated significant MR that can potentially lead to left ventricular (LV) failure after procedure. Considering the specific alterations in the mitral valve in TAVR scenario and the widespread use of TAVR in recent years, it appears important to know and understand the anatomical, functional and clinical implications to develop adequate strategies for the future. Patients with severe mitral regurgitation (MR) have been generally excluded from randomized clinical trials, making poor the impact that associated MR can have on clinical outcomes after TAVR. Read More

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http://dx.doi.org/10.21037/jtd.2020.01.69DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330403PMC

Association between right ventricle dysfunction and poor outcome in patients with septic shock.

Heart 2020 Jul 8. Epub 2020 Jul 8.

Department of Emergency Medicine, Asan Medical Center, Songpa-gu, Seoul, Republic of Korea

Objective: Sepsis-induced myocardial dysfunction (SIMD) can involve both the left and right ventricles. However, the characteristics and outcomes across various manifestations of SIMD remain unknown.

Methods: This was a retrospective cohort study using a prospective registry of septic shock from January 2011 and April 2017. Read More

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http://dx.doi.org/10.1136/heartjnl-2020-316889DOI Listing

Pathophysiology, Classification, and MRI Parallels in Microvascular Disease of the Heart and Brain.

Microcirculation 2020 Jul 8. Epub 2020 Jul 8.

Division of Cardiology, David Geffen School of Medicine at, UCLA and VA Greater Los Angeles Healthcare System.

Diagnostic imaging technology in vascular disease has long focused on large vessels and the pathologic processes that impact them. With improved diagnostic techniques, investigators are now able to uncover many underlying mechanisms and prognostic factors for microvascular disease. In the heart and brain, these pathologic entities include coronary microvascular disease and cerebral small vessel disease, both of which have significant impact on patients, causing angina, myocardial infarction, heart failure, stroke and dementia. Read More

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http://dx.doi.org/10.1111/micc.12648DOI Listing

COVID-19 and Decompressive Hemicraniectomy for Acute Ischemic Stroke.

Stroke 2020 Jul 8:STROKEAHA120030804. Epub 2020 Jul 8.

Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY. (J.W.L., A.S.R., K.R., C.L., C.P.K., T.S., J.G., S.M., J.B.B., J.M., N.S.D.).

Background And Purpose: Young patients with malignant cerebral edema have been shown to benefit from early decompressive hemicraniectomy. The impact of concomitant infection with coronavirus disease 2019 (COVID-19) and how this should weigh in on the decision for surgery is unclear.

Methods: We retrospectively reviewed all COVID-19-positive patients admitted to the neuroscience intensive care unit for malignant edema monitoring. Read More

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http://dx.doi.org/10.1161/STROKEAHA.120.030804DOI Listing

Tenascin-C aggravates ventricular dilatation and angiotensin-converting enzyme activity after myocardial infarction in mice.

ESC Heart Fail 2020 Jul 8. Epub 2020 Jul 8.

Ludwig Boltzmann Institute for Cardiovascular Research, Medical University of Vienna, Waehringer Guertel 18-20, 1Q, Vienna, 1090, Austria.

Aims: Tenascin-C (TN-C) is suggested to be detrimental in cardiac remodelling after myocardial infarction (MI). The aim of this study is to reveal the effects of TN-C on extracellular matrix organization and its haemodynamic influence in an experimental mouse model of MI and in myocardial cell culture during hypoxic conditions.

Methods And Results: Myocardial infarction was induced in TN-C knockout (TN-C KO) and wild-type mice. Read More

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http://dx.doi.org/10.1002/ehf2.12794DOI Listing

Systemic Amyloidosis Recognition, Prognosis, and Therapy: A Systematic Review.

JAMA 2020 Jul;324(1):79-89

Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, Minnesota.

Importance: Many patients with systemic amyloidosis are underdiagnosed. Overall, 25% of patients with immunoglobulin light chain (AL) amyloidosis die within 6 months of diagnosis and 25% of patients with amyloid transthyretin (ATTR) amyloidosis die within 24 months of diagnosis. Effective therapy exists but is ineffective if end-organ damage is severe. Read More

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http://dx.doi.org/10.1001/jama.2020.5493DOI Listing

[Cardiac scintigraphy-centered diagnostic process in transthyretin cardiac amyloidosis].

Turk Kardiyol Dern Ars 2020 Jul;48(5):514-521

Department of Cardiology, Eskişehir Osmangazi University Faculty of Medicine, Eskişehir, Turkey.

Cardiac amyloidosis (CA) is a progressive infiltrative cardiomyopathy. Amyloid fibrils in the form of misfolded endogenous proteins accumulate in the heart, as well as the kidneys, liver, and gastrointestinal tract. The most common forms of CA are transthyretin (TTR) and immunoglobulin light chain amyloidosis (AL). Read More

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http://dx.doi.org/10.5543/tkda.2020.90914DOI Listing

Ischemia and Viability Testing in New-Onset Heart Failure.

Curr Cardiol Rep 2020 Jul 6;22(8):76. Epub 2020 Jul 6.

Division of Cardiology, Cook County Health, 1901 W. Harrison St. Suite 3620, Chicago, IL, 60612, USA.

Purpose Of Review: To examine the utility and methods of coronary artery disease (CAD) assessment in patients with new-onset heart failure with reduced ejection fraction (HFrEF) of unclear etiology. Moreover, we sought to review the role and techniques of assessing myocardial viability to guide coronary revascularization in patients with established ischemic cardiomyopathy.

Recent Findings: Data indicates that surgical coronary revascularization in patients with HFrEF due to ischemic cardiomyopathy leads to lower long-term all-cause mortality and cardiovascular hospitalizations. Read More

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http://dx.doi.org/10.1007/s11886-020-01304-2DOI Listing

Left Ventricular Geometry and Replacement Fibrosis Detected by cMRI Are Associated with Major Adverse Cardiovascular Events in Nonischemic Dilated Cardiomyopathy.

J Clin Med 2020 Jun 25;9(6). Epub 2020 Jun 25.

Department of Internal Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, 400006 Cluj-Napoca, Romania.

To investigate the relationship between left ventricular (LV) long-axis strain (LAS) and LV sphericity index (LVSI) and outcomes in patients with nonischemic dilated cardiomyopathy (NIDCM) and myocardial replacement fibrosis confirmed by late gadolinium enhancement (LGE) using cardiac magnetic resonance imaging (cMRI), we conducted a prospective study on 178 patients (48 ± 14.4 years; 25.2% women) with first NIDCM diagnosis. Read More

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http://dx.doi.org/10.3390/jcm9061997DOI Listing

The role of cardiovascular imaging in cancer patients receiving cardiotoxic therapies: a Position statement on behalf of the Heart Failure Association (HFA), the European Association of Cardiovascular Imaging (EACVI) and the Cardio-Oncology Council of the European Society of Cardiology (ESC).

Eur J Heart Fail 2020 Jul 4. Epub 2020 Jul 4.

National Heart and Lung Institute, Imperial College, London, United Kingdom.

Cardiovascular (CV) imaging is an important tool in baseline risk assessment and detection of CV disease in oncology patients receiving cardiotoxic cancer therapies. This position statement examines the role of echocardiography, cardiac magnetic resonance, nuclear cardiac imaging and computed tomography in the management of cancer patients. The Imaging and Cardio-Oncology Study Groups of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC) in collaboration with the European Association of Cardiovascular Imaging (EACVI) and the Cardio-Oncology Council of the ESC have evaluated the current evidence for the value of modern CV imaging in the cardio-oncology field. Read More

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http://dx.doi.org/10.1002/ejhf.1957DOI Listing

Regional Adiposity and Heart Failure with Preserved Ejection Fraction.

Eur J Heart Fail 2020 Jul 3. Epub 2020 Jul 3.

Division of Cardiology, Duke University School of Medicine, Durham, North Carolina, United States.

The role of obesity in the pathogenesis of heart failure (HF), and in particular HF with preserved ejection fraction (HFpEF), has drawn significant attention in recent years. The prevalence of both obesity and HFpEF has increased worldwide over the past decades and when present concomitantly suggests an obese-HFpEF phenotype. Anthropometrics, including body mass index (BMI), waist circumference (WC), and waist-hip-ratio (WHR), are associated with incident HFpEF. Read More

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http://dx.doi.org/10.1002/ejhf.1956DOI Listing

Case report: adult-onset manifesting heterozygous glycogen storage disease type IV with dilated cardiomyopathy and absent late gadolinium enhancement on cardiac magnetic resonance imaging.

Eur Heart J Case Rep 2020 Jun 3;4(3):1-6. Epub 2020 May 3.

Department of Radiology, Jacobi Medical Center, 1400 Pelham Pkwy S, Bronx, NY 10461, USA.

Background: Glycogen storage disease type IV (GSD IV; Andersen's disease) is a rare autosomal recessive disease caused by mutation in the GBE1 gene. Presentation of GSD IV varies on a continuum of severity and symptomatology ranging from neonatal death to mild adult-onset disease with variable involvement of hepatic, muscular, neurologic, dermatologic, and cardiac systems. Cardiomyopathy seen in GSD IV is also heterogeneous and its appearance on cardiac magnetic resonance imaging (CMR) is rarely described. Read More

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http://dx.doi.org/10.1093/ehjcr/ytaa078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319828PMC

Methylephedrine-induced heart failure in a habitual user of paediatric cough syrup: a case report.

Eur Heart J Case Rep 2020 Jun 27;4(3):1-4. Epub 2020 Apr 27.

Department of Cardiology, Pulmonology, Hypertension, and Nephrology, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime 791-0295, Japan.

Background: For relief of cold symptoms, methylephedrine is considered to be safer than ephedrine, particularly when used at the predetermined dose. It is often present in various over-the-counter (OTC) drugs for cold, including paediatric cough syrups.

Case Summary: A 52-year-old man presented with worsening dyspnoea and anorexia for 2 weeks. Read More

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http://dx.doi.org/10.1093/ehjcr/ytaa095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319816PMC

Late atrioventricular groove disruption presenting 7 years after mitral valve replacement: a case report.

Eur Heart J Case Rep 2020 Jun 1;4(3):1-5. Epub 2020 May 1.

Department of Cardiovascular Surgery, Hospital das Clínicas, Universidade Federal de Minas Gerais, Avenida Professor Alfredo Balena n 110, Belo Horizonte MG 30.130-100, Brazil.

Background: Left ventricular rupture is the most feared complication in mitral valve surgery. Despite its low incidence, mortality rates can reach up to 75%. It usually presents on the operating room with a dissecting haematoma followed by massive bleeding after discontinuing cardiopulmomary bypass. Read More

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http://dx.doi.org/10.1093/ehjcr/ytaa091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319809PMC

Recent Updates on Vascular Complications in Patients with Type 2 Diabetes Mellitus.

Endocrinol Metab (Seoul) 2020 Jun 24;35(2):260-271. Epub 2020 Jun 24.

Division of Endocrinology and Metabolism, Department of Internal Medicine, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea.

It is well known that patients with type 2 diabetes mellitus (T2DM) are at an increased risk of morbidity and mortality from atherosclerotic cardiovascular (CV) complications. Previously, the concept that diabetes mellitus (DM) is a "coronary artery disease (CAD) risk equivalent" was widely accepted, implying that all DM patients should receive intensive management. However, considerable evidence exist for wide heterogeneity in the risk of CV events among T2DM patients and the concept of a "CAD risk equivalent" has changed. Read More

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http://dx.doi.org/10.3803/EnM.2020.35.2.260DOI Listing

Nonalcoholic fatty liver disease and cardiovascular disease phenotypes.

SAGE Open Med 2020 20;8:2050312120933804. Epub 2020 Jun 20.

Department of Neuroscience, Imaging and Clinical Sciences, Institute for Advanced Biomedical Technologies, "G. d'Annunzio" University of Chieti and Pescara, Chieti, Italy.

Nonalcoholic fatty liver disease is increasingly recognized as a major global health problem. Intertwined with diabetes, metabolic syndrome, and obesity, nonalcoholic fatty liver disease embraces a spectrum of liver conditions spanning from steatosis to inflammation, fibrosis, and liver failure. Compared with the general population, the prevalence of cardiovascular disease is higher among nonalcoholic fatty liver disease patients, in whom comprehensive cardiovascular risk assessment is highly desirable. Read More

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http://dx.doi.org/10.1177/2050312120933804DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7307287PMC

Calcineurin Aβ-Specific Anchoring Confers Isoform-Specific Compartmentation and Function in Pathological Cardiac Myocyte Hypertrophy.

Circulation 2020 Jul 2. Epub 2020 Jul 2.

Interdisciplinary Stem Cell Institute, Department of Pediatrics, Leonard M. Miller School of Medicine University of Miami, Miami, FL; Departments of Ophthalmology and Medicine, Stanford Cardiovascular Institute, Stanford University, Palo Alto, CA.

The Ca/calmodulin-dependent phosphatase calcineurin is a key regulator of cardiac myocyte hypertrophy in disease. An unexplained paradox is how the Aβ isoform of calcineurin (CaNAβ) is required for induction of pathological myocyte hypertrophy, despite calcineurin Aα expression in the same cells. In addition, it is unclear how the pleiotropic second messenger Ca drives excitation-contraction coupling, while not stimulating hypertrophy via calcineurin in the normal heart. Read More

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http://dx.doi.org/10.1161/CIRCULATIONAHA.119.044893DOI Listing

Atrial functional mitral regurgitation: mechanisms and surgical implications.

Asian Cardiovasc Thorac Ann 2020 Jul 1:218492320941388. Epub 2020 Jul 1.

Division of Cardiology, Department of Medicine and Therapeutics, Laboratory of Cardiac Imaging and 3D Printing, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong.

The term atrial functional mitral regurgitation refers to a newly recognized disease entity in which mitral regurgitation occurs secondary to left atrial disease, without left ventricular dilatation and intrinsic mitral valve disease, typically in the setting of long-standing atrial fibrillation. Recent evidence suggests that atrial functional mitral regurgitation is associated with increased risk of death and heart failure re-hospitalization. The etiology, pathophysiology, and mechanism of atrial functional mitral regurgitation is not completely understood but they should not be regarded as the same as for the conventional type of functional mitral regurgitation secondary to left ventricular dilatation and dysfunction. Read More

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http://dx.doi.org/10.1177/0218492320941388DOI Listing

Cardiac MRI in Pulmonary Hypertension: From Magnet to Bedside.

Radiographics 2020 Jul-Aug;40(4):982-1002

From the Department of Radiology, Hospital San Juan de Dios, Hospital de la Cruz Roja, RESSALTA HT Médica, Avenida el Brillante 36, 14012 Córdoba, Spain (J.B.); Cardiothoracic Imaging Section, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Mo (S.B., F.R.G.); Department of Radiology, University of Colorado-Anschutz Medical Campus, Aurora, Colo (D.V.); Department of Radiology, Mayo Clinic, Rochester, Minn (E.E.W.); Cardiovascular Division, Barnes Jewish Heart and Vascular Center, St Louis, Mo (M.M.); and MRI Section, Department of Radiology, Clínica Las Nieves, SERCOSA HT Médica, Jaén, Spain (A.L.).

Pulmonary hypertension (PH) is a disease characterized by progressive rise of pulmonary artery (PA) pressure, which can lead to right ventricular (RV) failure. It is usually diagnosed late because of the nonspecificity of its symptoms. RV performance and adaptation to an increased afterload, reflecting the interaction of the PA and RV as a morphofunctional unit, constitute a critical determinant of morbidity and mortality in these patients. Read More

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http://dx.doi.org/10.1148/rg.2020190179DOI Listing

Design, development, testing at ISO standards and in vivo feasibility study of a novel polymeric heart valve prosthesis.

Biomater Sci 2020 Jul 1. Epub 2020 Jul 1.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK.

Clinically available prosthetic heart valves are life-saving, but imperfect: mechanical valves requiring anticoagulation therapy, whilst bioprosthetic valves have limited durability. Polymer valves offer the prospect of good durability without the need for anticoagulation. We report the design and development of a polymeric heart valve, its bench-testing at ISO standards, and preliminary extra-vivo and in vivo short-term feasibility. Read More

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http://dx.doi.org/10.1039/d0bm00412jDOI Listing

Biventricular imaging markers to predict outcomes in non-compaction cardiomyopathy: a machine learning study.

ESC Heart Fail 2020 Jun 30. Epub 2020 Jun 30.

Heart Institute (InCor) do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Av. Dr. Enéas de Carvalho Aguiar, 44, São Paulo, 05403-000, Brazil.

Aims: Left ventricular non-compaction cardiomyopathy (LVNC) is a genetic heart disease, with heart failure, arrhythmias, and embolic events as main clinical manifestations. The goal of this study was to analyse a large set of echocardiographic (echo) and cardiac magnetic resonance imaging (CMRI) parameters using machine learning (ML) techniques to find imaging predictors of clinical outcomes in a long-term follow-up of LVNC patients.

Methods And Results: Patients with echo and/or CMRI criteria of LVNC, followed from January 2011 to December 2017 in the heart failure section of a tertiary referral cardiologic hospital, were enrolled in a retrospective study. Read More

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http://dx.doi.org/10.1002/ehf2.12795DOI Listing

Erdheim-Chester Disease: a Rare but Important Cause of Recurrent Pericarditis.

Curr Cardiol Rep 2020 Jun 30;22(8):75. Epub 2020 Jun 30.

Section of Cardiovascular Imaging, Center for the Diagnosis and Treatment of Pericardial Diseases, Heart and Vascular Institute, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, 44195, USA.

Purpose Of Review: Erdheim-Chester disease (ECD) is a very rare neoplasm of the non-Langerhans cell histiocytes. Pericardial involvement is uncommon, and we aim to review the current knowledge on the epidemiology, clinical manifestations, and management of recurrent pericarditis due to ECD. We also aim to raise awareness of the importance of considering ECD as a differential diagnosis for recurrent pericarditis in the appropriate clinical settings. Read More

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http://dx.doi.org/10.1007/s11886-020-01307-zDOI Listing

Typical MRI Features of a Vein of Galen Aneurysmal Malformation.

J Belg Soc Radiol 2020 Jun 22;104(1):32. Epub 2020 Jun 22.

UCL, BE.

Typical imaging features of a vein of Galen aneurysmal malformation are enlarged intracranial arterial feeders to a dilated recipient vein. Read More

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http://dx.doi.org/10.5334/jbsr.2133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319071PMC

[Neonatal capillary malformation-arteriovenous malformation complicated with acute heart failure: a case report and literature review].

Zhonghua Er Ke Za Zhi 2020 Jul;58(7):591-595

Department of Neonatology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China.

To study the clinical characteristics and current treatment of neonatal capillary malformation-arteriovenous malformation (CM-AVM). Clinical data of a newborn diagnosed with neonatal CM-AVM caused by RASA1 gene variation admitted to Shanghai Children's Medical Center Affiliated to Shanghai Jiao Tong University School of Medicine was retrospectively analyzed, and related literature was reviewed. Databases of CNKI, WanFang, and Pubmed were searched for the literature from January 1, 2009 to December 31, 2018, with the keywords of "capillary malformation-arteriovenous malformation" "neonatal" and "RASA1 gene" . Read More

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http://dx.doi.org/10.3760/cma.j.cn112140-20200312-00221DOI Listing

[Perspectives of using pulmonary arterial stiffness indicators to evaluate the prognosis of patients with pulmonary arterial hypertension].

Ter Arkh 2018 Jan 15;90(1):86-92. Epub 2018 Jan 15.

Almazov National Medical Research Centre.

Objective: the aim of the study was to characterize the mechanical properties of the pulmonary arterial wall (PA) in patients with pulmonary arterial hypertension (PAH) using magnetic resonance imaging (MRI) of the heart, and to determine their diagnostic and prognostic value.

Materials And Methods: 57 patients with PAH were examined. The diagnosis of PAH was verified according to the recommendations of the ERS/ESC from 2015. Read More

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http://dx.doi.org/10.17116/terarkh201890186-92DOI Listing
January 2018

68Ga-DOTATOC PET for Treatment Efficacy Evaluation of Cardiac Sarcoidosis.

Clin Nucl Med 2020 Jun 25. Epub 2020 Jun 25.

From the Nuclear Medicine and Molecular Imaging, ICANS-University Hospitals of Strasbourg.

Cardiac sarcoidosis (CS) has a poor prognosis related to life-threating arrhythmias and heart failure. Treatment includes anti-inflammatory therapies and implantable pacemaker and/or cardioverter defibrillator. The presence of cardiac devices and physiologic myocardial glucose uptake are major limitations of both cardiac magnetic resonance and F-FDG PET/CT, reducing their diagnostic value. Read More

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http://dx.doi.org/10.1097/RLU.0000000000003185DOI Listing

Percutaneous Closure of Paravalvular Leak from a Rocking Mitral Valve in a 74-Year-Old Man at High Surgical Risk.

Tex Heart Inst J 2020 Apr;47(2):160-162

Division of Cardiology, Emory University School of Medicine, Atlanta, Georgia 30322.

Dehiscence of a prosthetic heart valve or excessive rocking during the cardiac cycle is thought to preclude percutaneous paravalvular leak closure. However, surgical repair of paravalvular leak is associated with recurrent dehiscence and poor outcomes. We present the case of a symptomatic 74-year-old man in whom we performed percutaneous anchoring, involving multiple plugs and multimodal imaging, to stabilize a rocking mitral valve and close a substantial paravalvular leak caused by dehiscence. Read More

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http://dx.doi.org/10.14503/THIJ-18-6626DOI Listing

Demonstrating the mechanism of electrical alternans in cardiac tamponade: "the swinging heart".

Med J Aust 2020 Jun 29. Epub 2020 Jun 29.

Government Medical College and Hospital, Chandigarh, India.

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http://dx.doi.org/10.5694/mja2.50687DOI Listing

Iron imaging in myocardial infarction reperfusion injury.

Nat Commun 2020 Jun 29;11(1):3273. Epub 2020 Jun 29.

Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.

Restoration of coronary blood flow after a heart attack can cause reperfusion injury potentially leading to impaired cardiac function, adverse tissue remodeling and heart failure. Iron is an essential biometal that may have a pathologic role in this process. There is a clinical need for a precise noninvasive method to detect iron for risk stratification of patients and therapy evaluation. Read More

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http://dx.doi.org/10.1038/s41467-020-16923-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324567PMC

Myofiber organization in the failing systemic right ventricle.

J Cardiovasc Magn Reson 2020 06 29;22(1):49. Epub 2020 Jun 29.

Cardiac Registry, Departments of Cardiology, Pathology and Cardiac Surgery, Boston Children's Hospital, 300 Longwood Ave, Boston, MA 02115, USA. and Department of Pediatrics, Harvard Medical School, Boston, MA, USA.

Background: The right ventricle (RV) often fails when functioning as the systemic ventricle, but the cause is not understood. We tested the hypothesis that myofiber organization is abnormal in the failing systemic right ventricle.

Methods: We used diffusion-weighted cardiovascular magnetic resonance imaging to examine 3 failing hearts explanted from young patients with a systemic RV and one structurally normal heart with postnatally acquired RV hypertrophy for comparison. Read More

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http://dx.doi.org/10.1186/s12968-020-00637-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322876PMC

Surgical "New Aortic Carrefour Technique" for late open conversion after Endovascular Aortic Repair.

Ann Vasc Surg 2020 Jun 26. Epub 2020 Jun 26.

Department of Vascular Surgery, University and Hospital Trust of Verona, University of Verona-School of Medicine, Verona, Italy.

Objectives: The aim of the study is to report the early and mid-term outcomes of late open conversion (LOC) after endovascular aortic repair (EVAR) using the "New Aortic Carrefour Technique" (NACT) for preservation of the stent-graft iliac limbs. Late conversions were defined as explants >6 months after previous EVAR.

Methods: Patients treated for elective or urgent LOC after EVAR with the "New Aortic Carrefour Technique" at a single centre (2009-2019), and with ≥6 months of follow-up, were included. Read More

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http://dx.doi.org/10.1016/j.avsg.2020.06.027DOI Listing

[Assessment of atrial fibrillation inducibility based on epicardial mapping signals].

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 2020 Jun;37(3):487-495

Department of Electronic Engineering, Fudan University, Shanghai 200433, P.R.China;Key Laboratory of Medical Imaging Computing and Computer Assisted Intervention of Shanghai, Shanghai 200093, P.R.China;Shanghai Engineering Research Center of Cardiac Electrophysiology, Shanghai 201318, P.R.China.

Atrial fibrillation (AF) is the most common arrhythmia in clinic, which can cause hemodynamic changes, heart failure and stroke, and seriously affect human life and health. As a self-promoting disease, the treatment of AF can become more and more difficult with the deterioration of the disease, and the early prediction and intervention of AF is the key to curbing the deterioration of the disease. Based on this, in this study, by controlling the dose of acetylcholine, we changed the AF vulnerability of five mongrel dogs and tried to assess it by analyzing the electrophysiology of atrial epicardium under different states of sinus rhythm. Read More

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http://dx.doi.org/10.7507/1001-5515.201910005DOI Listing

Assessment of left ventricular diastolic function by three-dimensional transthoracic echocardiography.

Echocardiography 2020 Jun 28. Epub 2020 Jun 28.

Department of Cardiological, Neural and Metabolic Sciences, Istituto Auxologico Italiano, IRCCS, San Luca Hospital, Milan, Italy.

Doppler echocardiography assessment of left ventricular (LV) filling pressures at rest and during exercise is the most widely used imaging technique to assess LV diastolic function in clinical practice. However, a sizable number of patients evaluated for suspected LV diastolic function show an inconsistency between the various parameters included in the flowchart recommended by current Doppler echocardiography guidelines and results in an undetermined LV diastolic function. Current three-dimensional echocardiography technology allows obtaining accurate measurements of the left atrial volumes and functions that have been shown to improve the diagnostic accuracy and prognostic value of the algorithms recommended for assessing both LV diastolic dysfunction and heart failure with preserved ejection fraction. Read More

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http://dx.doi.org/10.1111/echo.14782DOI Listing

Low preoperative superior vena cava blood flow predicts bidirectional cavopulmonary shunt failure.

J Thorac Cardiovasc Surg 2020 May 5. Epub 2020 May 5.

Division of Cardiovascular Surgery, The Labatt Family Heart Centre, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada; Department of Surgery, University of Toronto, Toronto, Ontario, Canada. Electronic address:

Background: In this study we sought to determine whether preoperative superior vena cava (SVC) blood flow measured using cardiac magnetic resonance (CMR) predicts physiology and clinical outcome after bidirectional cavopulmonary shunt (BCPS).

Methods: The retrospective single-center study included 65 (2012-2017) patients who underwent BCPS. Preoperative CMR imaging, echocardiography, catheterization, and clinical outcomes were reviewed. Read More

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http://dx.doi.org/10.1016/j.jtcvs.2020.04.098DOI Listing

Characterisation of patients with and without cardiac magnetic resonance imaging abnormalities presenting with myocardial infarction with non-obstructive coronary arteries (MINOCA).

Acta Cardiol 2020 Jun 29:1-9. Epub 2020 Jun 29.

Department of Cardiology, Aalborg University Hospital, Aalborg, Denmark.

The objective of the current study is to determine the characteristics of myocardial infarction with non-obstructive coronary arteries (MINOCA) patients with and without cardiac magnetic resonance (CMR) abnormalities. We evaluated patients admitted with a presentation of acute myocardial infarction (MI) with no coronary obstruction on invasive angiography in our institution between 2012 and 2017. Patients with prior cardiac disease, myocarditis, Takotsubo cardiomyopathy and type 2 myocardial infarction were excluded. Read More

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http://dx.doi.org/10.1080/00015385.2020.1785134DOI Listing

Cardiac mechanics in heart failure with preserved ejection fraction.

Echocardiography 2020 Jun 28. Epub 2020 Jun 28.

West Virginia University Medicine Heart and Vascular Institute, Morgantown, West Virginia, USA.

Heart failure with preserved ejection fraction (HFpEF) is a complex clinical entity associated with significant morbidity and mortality. Common comorbidities including hypertension, coronary artery disease, diabetes, chronic kidney disease, obesity, and increasing age predispose to preclinical diastolic dysfunction that often progresses to frank HFpEF. Clinical HFpEF is typically associated with some degree of diastolic dysfunction, but can occur in the absence of many conventional diastolic dysfunction indices. Read More

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http://dx.doi.org/10.1111/echo.14764DOI Listing

Current understanding and future perspectives of brain-heart-kidney axis in psoriatic arthritis.

Rheumatol Int 2020 Jun 27. Epub 2020 Jun 27.

Onassis Cardiac Surgery Center, 50 Esperou Street, 175-61 P. Faliro, Athens, Greece.

Psoriatic arthritis (PsA) patients are at a higher risk of systemic inflammatory sequelae, leading to microalbuminuria, cardiovascular (CVD) and neuropsychiatric (NPD) disease. Our aim is to present the existing literature about the relationship between CVD, kidney and NPD in PsA. The literature evaluation of PsA revealed that chronic T-cell activation and increased levels of circulating immune complexes can cause glomerular injury leading to microalbuminuria, which predicts CVD and all-cause mortality in both diabetic and non-diabetic patients. Read More

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http://dx.doi.org/10.1007/s00296-020-04633-1DOI Listing

The value of F-FDG PET/CT for the diagnosis of device-related infections in patients with a left ventricular assist device: a systematic review and meta-analysis.

Eur J Nucl Med Mol Imaging 2020 Jun 27. Epub 2020 Jun 27.

Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713GZ, Groningen, The Netherlands.

Background: Left ventricular assist devices (LVADs) are increasingly used for the treatment of advanced heart failure. LVADs improve quality of life and decrease mortality, but the driveline carries substantial risk for major infections. These device-related LVAD and driveline infections are difficult to diagnose with conventional imaging. Read More

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http://dx.doi.org/10.1007/s00259-020-04930-8DOI Listing

Sex-specific difference in the association between arterial stiffness and subclinical left ventricular dysfunction.

Eur Heart J Cardiovasc Imaging 2020 Jun 28. Epub 2020 Jun 28.

Department of Cardiovascular Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.

Aims : Increased arterial stiffness is one of the key mechanisms of heart failure with preserved ejection fraction (HFpEF). However, the possible association between arterial stiffness and subclinical left ventricular (LV) dysfunction and its sex-specific difference remains unclarified. LV strain is emerging as a highly sensitive tool to unmask early LV abnormalities. Read More

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http://dx.doi.org/10.1093/ehjci/jeaa156DOI Listing

Cardiac Sarcoidosis.

Authors:
David H Birnie

Semin Respir Crit Care Med 2020 Jun 27. Epub 2020 Jun 27.

Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.

Approximately 5% of patients with sarcoidosis will have cardiac involvement presenting with one or more of ventricular arrhythmias, conduction abnormalities, and heart failure. It is estimated that another 20 to 25% of pulmonary/systemic sarcoidosis patients have asymptomatic cardiac involvement ( disease). Cardiac presentations can be the first (and/or an unrecognized) manifestation of sarcoidosis in a variety of circumstances. Read More

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http://dx.doi.org/10.1055/s-0040-1712535DOI Listing

Circulating troponin and further left ventricular ejection fraction improvement in patients with previously recovered left ventricular ejection fraction.

ESC Heart Fail 2020 Jun 27. Epub 2020 Jun 27.

Division of Cardiology, Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Alberta, Canada.

Aims: The aim of this study is to determine factors associated with long-term recovery of left ventricular ejection fraction (LVEF) in patients with heart failure with reduced EF (HFrEF) and if further recovery also occurs in this group.

Methods And Results: Among 621 participants enrolled in the Alberta Heart Failure Etiology and Analysis Team (HEART) Study, 316 with Stage C HF underwent comprehensive imaging and biomarker testing at enrolment and at 1-year follow up. Using pre-enrolment data, HF with recovered EF (HFrecEF) was defined as an absolute improvement ≥5% in LVEF from the prior lowest LVEF value, with a final LVEF value > 35% at or prior to study baseline. Read More

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http://dx.doi.org/10.1002/ehf2.12863DOI Listing

Biomatrices for Heart Regeneration and Cardiac Tissue Modelling In Vitro.

Adv Exp Med Biol 2020 Jun 27. Epub 2020 Jun 27.

Department of Regenerative Medicine, State Research Institute Centre for Innovative Medicine, Vilnius, Lithuania.

Cardiac muscle is the hardest working muscle in the body, pumping approximately 70 g of blood with every heartbeat, circulating 9500 l of blood daily and contracting over 3 billion times during the average human's life. Heart failure - a heterogeneous syndrome - is a major and increasing health care problem worldwide and a leading cause of hospitalization and morbidity in elderly. Adequate heart tissue regeneration in human is lacking. Read More

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http://dx.doi.org/10.1007/5584_2020_564DOI Listing

Jugular venous catheter-associated thrombosis and fatal pulmonary embolism: A case report.

Medicine (Baltimore) 2020 Jun;99(26):e20873

Department of Critical Care Medicine, Harrison International Peace Hospital, Hebei, China.

Introduction: Central venous catheters related thrombosis (CRT) insertion has been shown to increase the risk of venous thromboembolism, particularly pulmonary embolism (PE). Nevertheless, deaths cased due to PE have been rarely reported.

Patient Concerns: A central venous catheter was introduced through the right jugular vein during the operation due to severe septic shock from a 57-year-old male patient. Read More

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http://dx.doi.org/10.1097/MD.0000000000020873DOI Listing

A publicly available virtual cohort of four-chamber heart meshes for cardiac electro-mechanics simulations.

PLoS One 2020 26;15(6):e0235145. Epub 2020 Jun 26.

School of Biomedical Engineering and Imaging Sciences, King's College London, London, City of London, United Kingdom.

Computational models of the heart are increasingly being used in the development of devices, patient diagnosis and therapy guidance. While software techniques have been developed for simulating single hearts, there remain significant challenges in simulating cohorts of virtual hearts from multiple patients. To facilitate the development of new simulation and model analysis techniques by groups without direct access to medical data, image analysis techniques and meshing tools, we have created the first publicly available virtual cohort of twenty-four four-chamber hearts. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0235145PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319311PMC

Computed tomography coronary angiography for patients with heart failure (CTA-HF): a randomized controlled trial (IMAGE-HF 1C).

Eur Heart J Cardiovasc Imaging 2020 Jun 26. Epub 2020 Jun 26.

Department of Medicine (Cardiology), The University of Ottawa Heart Institute and University of Ottawa, 40 Ruskin Street, Ottawa, ON K1Y 4W7, Canada.

Aims: This randomized controlled trial sought to determine the financial impact of an initial diagnostic strategy of coronary computed tomography angiography (CCTA) in patients with heart failure (HF) of unknown aetiology. Invasive coronary angiography (ICA) is used to investigate HF patients. CCTA may be a non-invasive cost-effective alternative to ICA. Read More

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http://dx.doi.org/10.1093/ehjci/jeaa109DOI Listing

Role of adjuvant carotid ultrasound in women undergoing stress echocardiography for the assessment of suspected coronary artery disease.

Open Heart 2020 Jun;7(1)

National Heart and Lung Institute, Imperial College London, London, UK

Objective: Due to the low prevalence of obstructive coronary artery disease (CAD) in women, stress testing has a relatively low predictive value for this. Additionally, conventional cardiovascular risk scores underestimate risk in women. This study sought to evaluate the role of atherosclerosis assessment using carotid ultrasound (CU) in women attending for stress echocardiography (SE). Read More

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http://dx.doi.org/10.1136/openhrt-2019-001188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319702PMC

Renal Artery Stenosis in the Patient with Hypertension: Prevalence, Impact and Management.

Integr Blood Press Control 2020 2;13:71-82. Epub 2020 Jun 2.

Ochsner Clinic Foundation, Department of Cardiovascular Medicine, New Orleans, LA, USA.

Atherosclerosis is the primary cause of renal artery stenosis. Atherosclerotic renal artery stenosis (ARAS) is associated with three clinical problems: renovascular hypertension, ischemic nephropathy and cardiac destabilization syndrome which pose huge healthcare implications. There is a significant rate of natural disease progression with worsening severity of renal artery stenosis when renal revascularization is not pursued in a timely manner. Read More

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http://dx.doi.org/10.2147/IBPC.S248579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276195PMC

COPD and acute myocardial infarction.

Eur Respir Rev 2020 Jun 23;29(156). Epub 2020 Jun 23.

Dept of Cardiology, Leiden University Medical Centre, Leiden, The Netherlands.

COPD is strongly associated with cardiovascular disease, in particular acute myocardial infarction (AMI). Besides shared risk factors, COPD-related factors, such as systemic inflammation and hypoxia, underlie the pathophysiological interaction between COPD and AMI. The prevalence of COPD amongst AMI populations ranges from 7% to 30%, which is possibly even an underestimation due to underdiagnoses of COPD in general. Read More

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http://dx.doi.org/10.1183/16000617.0139-2019DOI Listing