927 results match your criteria Congenitally Corrected Transposition


Familial Recurrence Patterns in Congenitally Corrected Transposition of the Great Arteries: an International Study.

Circ Genom Precis Med 2022 May 12:101161CIRCGEN121003464. Epub 2022 May 12.

Department of Pediatric Cardiology, CHRU Lille, France (A.H.).

Background: Congenitally corrected transposition of the great arteries (ccTGA) is a rare disease of unknown cause. We aimed to better understand familial recurrence patterns.

Methods: An international, multicentre, retrospective cohort study was conducted in 29 tertiary hospitals in 6 countries between 1990 and 2018, entailing investigation of 1043 unrelated ccTGA probands. Read More

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Atrial tachycardia ablation from the pulmonic valve in a patient with congenitally corrected transposition of great arteries.

HeartRhythm Case Rep 2022 Apr 21;8(4):264-266. Epub 2022 Jan 21.

State Key Laboratory of Cardiovascular Disease, Arrhythmia Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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Canadian Cardiovascular Society 2022 Guidelines for Cardiovascular Interventions in Adults with Congenital Heart Disease.

Can J Cardiol 2022 Apr 20. Epub 2022 Apr 20.

Cincinnati Children's Hospital Heart Institute, Cincinnati, Ohio, USA.

Interventions in Adults with Congenital Heart Disease (ACHD) focus on surgical and percutaneous interventions in light of rapidly evolving ACHD clinical practice. To bring rigor to our process and amplify the cumulative nature of evidence ACHD care we used the ADAPTE process; we systematically adjudicated, updated, and adapted existing guidelines by Canadian, American, and European cardiac societies between from 2010 to 2020. We applied this to interventions related to right and left ventricular outflow obstruction, tetralogy of Fallot, coarctation, aortopathy associated with bicuspid aortic valve, atrioventricular canal defects, Ebstein anomaly, complete and congenitally corrected transposition, and patients with the Fontan operation. Read More

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Congenitally corrected transposition of great arteries associated with interrupted aortic arch type A: a case report of an unusual association.

Eur Heart J Case Rep 2022 Apr 21;6(4):ytac118. Epub 2022 Mar 21.

Department of Pediatric Cardiology, Fundación Valle de Lili, Cali, Colombia.

In this article, we report the third case, to our knowledge, of a congenitally corrected transposition of the great arteries associated with an interrupted aortic arch. This is a more complex and rare presentation than dextro-transposition of great arteries with interrupted aortic arch. The child ultimately succumbed to sepsis before the surgical repair was possible. Read More

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Congenitally Corrected Transposition Cardiac Surgery: Society of Thoracic Surgeons Database Analysis.

Ann Thorac Surg 2022 Apr 14. Epub 2022 Apr 14.

Division of Pediatric Cardiology, Vanderbilt University Medical Center, Nashville, Tennessee.

Background: Congenitally corrected transposition of the great arteries (ccTGA) has many management strategies, with the emergence of anatomic repair increasing the available surgical options. Contemporary surgical practices have not been described in multicenter analyses. This study describes the distribution of heart surgery in patients with ccTGA and defines contemporary outcomes in a large multicenter cohort. Read More

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Anaesthetic management of a patient with complex, cyanotic congenitally corrected transposition of great arteries for electrophysiological study and thermoablation.

BMJ Case Rep 2022 Apr 15;15(4). Epub 2022 Apr 15.

Anaesthesia and Surgical Intensive Care, Singapore General Hospital, Singapore.

Congenitally corrected transposition of great arteries (ccTGA) is a rare congenital heart disease, and little literature is available that describes its anaesthetic management. We present the perioperative management of a patient with complex, cyanotic ccTGA who underwent electrophysiological study with catheter ablation under general anaesthesia. Good understanding of the patient's complex cardiac anatomy and physiology and multidisciplinary communication are vital to facilitate the successful care of the patient. Read More

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Unusual case of complete situs inversus with congenitally corrected transposition of the great arteries with levocardia: imaging with MDCT.

BMJ Case Rep 2022 04 15;15(4). Epub 2022 Apr 15.

Radiodiagnosis, Lokmanya Tilak Municipal Medical College and General Hospital, Mumbai, India.

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Congenitally corrected transposition with absent pulmonary valve: Hitherto unreported association.

J Card Surg 2022 Apr 12. Epub 2022 Apr 12.

Department of Radiodiagnosis, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Absent pulmonary valve has usually been described in association with tetralogy of Fallot. Present case highlights its association with congenitally corrected transposition which has not been reported so far in literature. Read More

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Congenitally Corrected Transposition of the Great Arteries: Untangling the Mechanisms of Right Ventricular Dysfunction.

JACC Cardiovasc Imaging 2022 04 16;15(4):575-577. Epub 2022 Feb 16.

Division of Cardiology, University of Toronto, Toronto, Canada; Toronto ACHD Program, University Health Network and Mount Sinai Hospital, Toronto, Canada.

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The first experience with sodium-glucose cotransporter 2 inhibitor for the treatment of systemic right ventricular failure.

ESC Heart Fail 2022 Jun 30;9(3):2007-2012. Epub 2022 Mar 30.

CAHAL, Center for Congenital Heart Disease Amsterdam Leiden, Leiden University Medical Center, Leiden, The Netherlands.

In congenitally corrected transposition of the great arteries, the morphological right ventricle supports the systemic circulation. This chronic exposure to pressure overload ultimately leads to systemic right ventricular (sRV) dysfunction and heart failure. Pharmacological options for the treatment of sRV failure are poorly defined and no solid recommendations are made in the most recent guidelines. Read More

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Heartmate 3 as a bridge to heart transplantation in a patient with congenitally corrected transposition of the great arteries: a case report.

J Cardiothorac Surg 2022 Mar 26;17(1):54. Epub 2022 Mar 26.

The Division of Cardiovascular and Thoracic Surgery, Rabin Medical Center, Petach-Tikva, Israel.

Background: We report the first use of Heartmate 3 (HM3) in a Congenitally corrected Transposition of the Great Arteries (ccTGA) as a Systemic Ventricular Assist Device (SVAD) to treat HF.

Case Presentation: A 55 years old man with a Congenitally corrected Transposition of the Great Arteries (ccTGA) a rare condition in which Heart Failure (HF) is a common presentation in adult life and survival without heart transplantation is hardly an option. Systemic Ventricular Assist Device (SVAD) can be an option if an organ does not become available. Read More

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Complete heart block in a young adult with non-isolated congenitally corrected transposition of the great arteries: Case report.

Ann Med Surg (Lond) 2022 Apr 14;76:103500. Epub 2022 Mar 14.

Mohammed V University, Rabat, Morocco.

Introduction And Importance: Congenitally corrected transposition of the great arteries (ccTGA) or L-looped transposition of the great arteries (L-TGA) is a very rare and complex form of congenital heart disease. The majority of patients with ccTGA have at least one or more associated congenital heart disorders, essentially ventricular septal defects. Patients with ccTGA can remain asymptomatic for a long time and the diagnosis can sometimes be made late in life at the stage of complications. Read More

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Infective endocarditis in an adult with unrepaired corrected transposition.

SAGE Open Med Case Rep 2022 15;10:2050313X221085101. Epub 2022 Mar 15.

Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.

We report a case of a 28-year-old man with unrepaired congenitally corrected transposition of the great arteries, ventricular septal defect, and pulmonary stenosis who presented with septic shock due to infective endocarditis by . The cardiac catheterization had the risk of vegetation scattering. Without invasive hemodynamic assessment, the degree of pulmonary stenosis and left ventricle preparation as a systemic ventricle could not be accurately determined, making surgical planning difficult. Read More

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Commentary: Time for a multi-institutional study for congenitally corrected transposition of great arteries?

J Thorac Cardiovasc Surg 2022 Feb 16. Epub 2022 Feb 16.

Department of Cardiovascular Surgery, Hospital for Sick Children, Toronto, Ontario, Canada. Electronic address:

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February 2022

Double Switch in Congenitally Corrected Transposition of the Great Arteries With Incomplete Atrioventricular Septal Defect, Ebsteinoid Tricuspid Valve, Ventricular Outflow Tract Obstructions, and Multiple VSDs.

World J Pediatr Congenit Heart Surg 2022 Mar 11:21501351221085544. Epub 2022 Mar 11.

Department of Thoracic and Cardiovascular Surgery, Heart, Vascular, and Thoracic Institute, 2569Cleveland Clinic Foundation, Cleveland, OH, USA.

We describe the management of a 2 month-old male (BSA 0.27 m) with congenitally corrected transposition of the great arteries (CCTGA), left and right ventricular outflow tract obstruction, incomplete atrioventricular (AV) canal defect, Ebsteinoid left AV valve, and multiple VSDs. In short, the patient presented with respiratory failure, metabolic acidosis with worsening AV valve regurgitation, and acute decompensation from pulmonary overcirculation. Read More

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Ventricular assist devices in transposition and failing systemic right ventricle: role of tricuspid valve replacement.

Eur J Cardiothorac Surg 2022 Mar 4. Epub 2022 Mar 4.

Adult Congenital and Paediatric Heart Unit, Freeman Hospital, Newcastle Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.

Objectives: Ventricular assist device (VAD) for systemic right ventricular (RV) failure patients post-atrial switch, for transposition of the great arteries (TGA), and those with congenitally corrected TGA has proven useful to reduce transpulmonary gradient and bridge-to-transplantation. The purpose of this study is to describe our experience of VAD in systemic RV failure and our move towards concomitant tricuspid valve replacement (TVR).

Methods: This is a single-centre retrospective study of consecutive adult patients receiving HeartWare VAD for systemic RV failure between 2010 and 2019. Read More

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Late presentation of congenitally corrected transposition of the great arteries.

BMJ Case Rep 2022 Mar 3;15(3). Epub 2022 Mar 3.

Department of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba, Japan.

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Target of atypical atrioventricular nodal reentrant tachycardia in congenitally corrected transposition of great vessels.

J Interv Card Electrophysiol 2022 Feb 22. Epub 2022 Feb 22.

Division of Cardiology, the First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Rd, Nanjing, 210029, China.

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February 2022

Congenitally Corrected Transposition of the Great Arteries: Mid-term Outcomes of Different Surgical Strategies.

Front Pediatr 2021 3;9:791475. Epub 2022 Feb 3.

Department of Cardiology, Shanghai Children's Medical Center Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Background: Optimal management for congenitally corrected transposition of the great arteries (ccTGA) is controversial. We applied different surgical strategies based on individual variations in our single-centered practice over 10 years, aming to describe the mid-term results.

Methods: From January 2008 to June 2021, 90 patients with ccTGA were reviewed and grouped by three different surgical strategies: 41 cases with biventricular correction as biventricular group, 11 cases with 1. Read More

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February 2022

Anatomic Repair of Congenitally Corrected Transposition: Reappraisal of Eligibility Criteria.

Pediatr Cardiol 2022 Feb 11. Epub 2022 Feb 11.

Department of Congenital Heart Surgery, German Heart Center Berlin, Augustenburger Platz 1, 13353, Berlin, Germany.

Several criteria to identify suitable candidates for anatomic repair in congenitally corrected transposition (cc-TGA) have been proposed. The purpose of this study was to critically re-evaluate adequacy of these recommendations in our patient cohort. All cc-TGA patients undergoing anatomic repair between 2010 and 2019 were reviewed. Read More

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February 2022

Cardiovascular Phenotypes Profiling for L-Transposition of the Great Arteries and Prognosis Analysis.

Front Cardiovasc Med 2021 21;8:781041. Epub 2022 Jan 21.

Department of Laboratory Medicine, National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Objectives: Congenitally corrected transposition of the great arteries (ccTGA) is a rare and complex congenital heart disease with the characteristics of double discordance. Enormous co-existed anomalies are the culprit of prognosis evaluation and clinical decision. We aim at delineating a novel ccTGA clustering modality under human phenotype ontology (HPO) instruction and elucidating the relationship between phenotypes and prognosis in patients with ccTGA. Read More

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January 2022

Iatrogenic ventricular septal defect during right ventricular assist device insertion in congenitally corrected transposition of the great arteries.

J Card Surg 2022 Apr 27;37(4):1080-1082. Epub 2022 Jan 27.

Division of Cardiovascular Surgery, Labatt Family Heart Centre, The Hospital for Sick Children, Toronto, Canada.

This case report describes the management of a large iatrogenic ventricular septal defect (VSD) created by the coring device during systemic ventricular assist device (right ventricular assist device [RVAD]) insertion in a 16-year-old patient with congenitally corrected transposition of the great arteries. The VSD was closed by a bovine pericardial patch and the ventriculotomy was extended laterally to relocate the VAD sewing ring. After RVAD implantation, the patient initially remained cyanotic, potentially due to a tiny VSD patch leak with right-to-left shunting. Read More

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Bicuspid aortic valve and anomalous origin of the right ventricular branch in a patient with congenitally corrected transposition of great arteries: A rare association.

J Card Surg 2022 Apr 20;37(4):1044-1046. Epub 2022 Jan 20.

Department of Cardiovascular Radiology and Endovascular Interventions, All India Institute of Medical Sciences, New Delhi, India.

We hereby present a case of congenitally corrected transposition of great arteries association of bicuspid aortic valve morphology and anomalous separate origin of the right ventricular branch of the right coronary artery. We aim to highlight the role of computed tomography angiography in identifying these rare associations. Read More

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Cardiac MRI predictors of adverse outcomes in adults with a systemic right ventricle.

ESC Heart Fail 2022 04 20;9(2):834-841. Epub 2022 Jan 20.

Division of Cardiology, Department of Medicine, Schneeweiss Adult Congenital Heart Center, Columbia University Medical Center, New York, NY, USA.

Aims: Predicting risk in individuals with a systemic right ventricle (SRV) remains difficult. We assessed the value of cardiac MRI (CMR) for predicting death, heart transplantation (HT), or need for a ventricular assist device (VAD) in adults with D-transposition of the great arteries (DTGA) post Mustard/Senning and in adults with congenitally corrected transposition of the great arteries (ccTGA) at two large academic centres.

Methods And Results: Between December 1999 and November 2020, 158 adult patients with an SRV underwent CMR. Read More

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A case report of late physiologic repair of congenitally corrected transposition of the great arteries and pulmonary stenosis in a severely cyanotic patient: better late than never.

Eur Heart J Case Rep 2022 Jan 28;6(1):ytab523. Epub 2021 Dec 28.

Pediatric and Congenital Cardiac Surgery, IRCCS-Policlinico San Donato, Milano, Italy.

Background: Patients with congenitally corrected transposition of great arteries (ccTGA) not infrequently seek medical attention for the first time late in life. Optimal management of natural history ccTGA is debated and must be tailored.

Case Summary: A 38-year-old male patient was referred to our centre because of severe cyanosis and worsening dyspnoea. Read More

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January 2022

MitraClip repair of right-sided atrioventricular valve in a patient with congenitally corrected transposition of the great arteries: a case report.

Eur Heart J Case Rep 2022 Jan 4;6(1):ytab479. Epub 2021 Dec 4.

Section of Cardiac Imaging and Structural Heart Disease, Robert and Suzanne Tomsich Department of Cardiology, Heart and Vascular Institute, Cleveland Clinic Florida, 2950 Cleveland Clinic Blvd, Desk 23/24, Weston, FL 33331, USA.

Background: Patients with congenitally corrected transposition of the great arteries (ccTGA) often develop tricuspid valve (systemic atrioventricular valve) dysfunction due to right ventricular overload and dilatation, but isolated mitral valve (MV) disease is rarely found. Isolated mitral (subpulmonic atrioventricular valve) interventions, specifically catheter-directed, have not been reported up to date.

Case Summary: A man with ccTGA is evaluated for dyspnoea. Read More

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January 2022

From Other Journals: A Review of Recent Articles by Our Editorial Team.

Pediatr Cardiol 2022 Feb 10;43(2):475-480. Epub 2022 Jan 10.

Heart Institute, Johns Hopkins All Children's All Children's Hospital, St. Petersburg, FL, USA.

In this review, we provide a brief description of recently published articles addressing topics relevant to pediatric cardiologists. Our hope is to provide a summary of the latest articles published recently in other journals in our field. The articles address the extracardiac anomalies in fetuses with congenital heart disease, post COVID-19 vaccination myocarditis, the use of cardiac magnetic resonance after the Fontan operation, congenitally corrected transposition in adults, robitically assisted congenital heart surgery and the increased risk of congenital heart surgery in patients receiving tracheal surgery during the same admission. Read More

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February 2022