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    [Vitiligo occurring on dermal melanocytosis (nevus of Ota) in a dark-skinned patient].
    Ann Dermatol Venereol 2017 Jul 17. Epub 2017 Jul 17.
    Service de dermatologie, CHU, Treichville, Côte d'Ivoire.
    Background: Nevus of Ota is a rare disease most frequently found in Asians. It presents clinically as a bluish gray hyperpigmentation of one side of the face. Transformation into melanoma and glaucoma are the main risks. Read More
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    Association between risk factors and detection of cutaneous melanoma in the setting of a population-based skin cancer screening.
    Eur J Cancer Prev 2017 Jul 7. Epub 2017 Jul 7.
    aInstitute of Social Medicine and Epidemiology bInstitute of Cancer Epidemiology, University of Lübeck, Lübeck, Germany cDepartment of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, Massachusetts dCenter for Dermatoepidemiology, VA Medical Center Providence eDepartment of Dermatology, Rhode Island Hospital, Providence fDepartments of Dermatology and Epidemiology, Brown University, Providence, Rhode Island, USA gDermatology Center, Division of Molecular Cell Biology, Elbe Clinics Stade-Buxtehude, Buxtehude hAssociation of Dermatological Prevention e.V., Hamburg, Germany.
    Early detection is considered to improve the prognosis of cutaneous melanoma. The value of population-based screening for melanoma, however, is still controversial. The aim of this study was to evaluate the predictive power of established risk factors in the setting of a population-based screening and to provide empirical evidence for potential risk stratifications. Read More
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    Treating Giant Congenital Nevus With Integra Dermal Regeneration Template in a 9-Year-Old Girl.
    Int J Low Extrem Wounds 2017 06 17;16(2):143-145. Epub 2017 Apr 17.
    4 Department of neurology, General hospital Bjelovar, Bjelovar, Croatia.
    Integra dermal regeneration template has been well established in treating deep extensive burns, but there are very few cases reported of treating large full-thickness skin defects such as giant nevi. Apart from psychological and cosmetic burdens, the giant congenital nevus carries increased risk of malignant alteration. We present the case of a 9-year-old girl with a giant congenital nevus on her left lower leg. Read More
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    Anatomic mapping and clinicopathologic analysis of benign acral melanocytic neoplasms: A comparison between adults and children.
    J Am Acad Dermatol 2017 Jul 1. Epub 2017 Jul 1.
    Department of Dermatology, Chonnam National University Medical School, Gwangju, Korea. Electronic address:
    Background: The clinicopathologic features of benign acral melanocytic neoplasms (BAMNs) remain poorly understood.

    Objective: To define the clinicopathologic features of BAMNs.

    Methods: We analyzed clinical data and mapped BAMNs anatomically. Read More
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    Sturge Weber Syndrome: A Case Study.
    J Clin Diagn Res 2017 May 1;11(5):ZD12-ZD14. Epub 2017 May 1.
    Postgraduate Student, Department of Oral Medicine and Radiology, Lenora Institute of Dental Sciences, Rajanagaram, Rajahmundry, Andhra Pradesh, India.
    The aim of this case review was to touch upon the various clinical presentations and diagnostic features of Sturge-Weber syndrome (SWS) as seen in the dental/medical practice. Sturge-Weber syndrome is a rare congenital disorder that belongs to a group of disorders collectively known as the phakomatoses. The characteristic pathological elements of the disease include leptomeninges angioma extending out to cerebral cortex with angiomatous lesions on the same side and unilateral facial nevus that affects trigeminal nerve division. Read More
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    Update on classification and diagnosis of vascular malformations.
    Curr Opin Pediatr 2017 Aug;29(4):448-454
    CHU Sainte-Justine, University of Montreal, Montreal, Québec, Canada.
    Purpose Of Review: This review provides an update of the classification in the classification of vascular anomalies since April 2014 at the International Society for the Study of Vascular Anomalies meeting in Melbourne, Australia.

    Recent Findings: The reader will become familiar with how to diagnose the major vascular malformations, including capillary, venous, arteriovenous, and lymphatic and combinations thereof. In addition, vascular malformation syndromes, including those with overgrowth, will be clarified. Read More
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    Successful Treatment of Unilateral Klippel-Trenaunay Syndrome With Pulsed-Dye Laser in a 2-Week Old Infant.
    J Lasers Med Sci 2017 28;8(2):98-100. Epub 2017 Mar 28.
    Skin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
    Introduction: Klippel-Trenaunay syndrome (KTS) is a rare congenital mesodermal abnormality characterized by varicose veins, cutaneous capillary malformation, as well as bone and soft tissue hypertrophy. Case Report: A 2-week-old female infant presented to our clinic because of vascular nevus and progressive enlargement of her right extremities and trunk since birth. The patient was treated with 595-nm pulsed-dye laser (PDL). Read More
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    Sonographic screening for Wilms tumor in children with CLOVES syndrome.
    Pediatr Blood Cancer 2017 Jun 19. Epub 2017 Jun 19.
    Vascular Anomalies Center, Boston Children's Hospital, Boston, Massachusetts.
    Background: CLOVES syndrome is associated with somatic mosaic PIK3CA mutations and characterized by congenital lipomatous overgrowth, vascular malformations, epidermal nevi, and skeletal anomalies. Wilms tumor (WT) is a malignant embryonal renal neoplasm associated with hemihypertrophy and certain overgrowth disorders. After identifying WT in a child with CLOVES, we questioned whether ultrasonographic screening was necessary in these patients. Read More
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    [PIK3CA-related overgrowth syndrome (PROS)].
    Nephrol Ther 2017 Apr;13 Suppl 1:S155-S156
    Inserm U1151, hôpital Necker-Enfants malades, 149, rue de Sèvres, 75015 Paris, France; Université Paris Descartes, Sorbonne Paris Cité, 149, rue de Sèvres, 75015 Paris, France; Service de néphrologie transplantation adultes, hôpital Necker-Enfants malades, 149, rue de Sèvres, 75015 Paris, France. Electronic address:
    This review presents an overview of a recently characterized spectrum of overgrowth syndrome: phosphoinositide-3 kinase (PI3K)-related overgrowth spectrum (PROS). This spectrum encompasses overgrowth syndromes associated with somatic mosaic activating PIK3CA mutations such as megalencephaly-capillary malformation (MCAP) syndrome, dysplatic megalencephaly (DMEG), congenital lipomatous asymmetric overgrowth of the trunk, lymphatic, capillary, venous, and combined-type vascular malformations, epidermal nevi, skeletal and spinal anomalies (CLOVES) syndrome, hemihyperplasia-multiple lipomatosis (HHML), fibroadipose overgrowth and Klippel-Trenaunay syndrome. Mosaic gain of function mutation in PIK3CA gene leads to abnormal AKT-mTOR pathway activation and is responsible of the clinical manifestations. Read More
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    Prelaminated extended temporoparietal fascia flap without tissue expansion for hemifacial reconstruction.
    J Plast Reconstr Aesthet Surg 2017 May 24. Epub 2017 May 24.
    Plastic, Reconstructive and Aesthetic Surgery Department, İstanbul University Cerrahpasa Medical Faculty, İstanbul, Turkey. Electronic address:
    Background: Disfigurement of the face caused by postburn scars, resected congenital nevi and vascular malformations has both functional and psychological consequences. Ideal reconstruction of the facial components requires producing not only function but also the better appearance of the face. The skin of the neck, supraclavicular or cervicothoracic regions are the most commonly used and the most likely source of skin for facial reconstruction in those techniques which prefabrications with tissue expansion are used. Read More
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    CLOVES Syndrome: Severe Neonatal Presentation.
    J Clin Diagn Res 2017 Apr 1;11(4):TR01-TR03. Epub 2017 Apr 1.
    Resident, Department of Plastic Surgery Section, Surgery Division, Medical School, Pontificia Universidad Católica de Chile, Santiago, Santiago, Chile.
    Congenital Lipomatous Overgrowth, Vascular Malformations, Epidermal Nevi and Spinal Abnormalities (CLOVES syndrome) is a newly described and rare overgrowth disorder with serious morbidity. The course of this disease is not well understood and few cases have been reported among neonates. Moreover, not all of the signs of this syndrome are present at birth, making a high index of suspicion necessary. Read More
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    Congenital Atrophic Plaque: Fibroblastic Connective Tissue Nevus.
    Pediatr Dermatol 2017 Jul 23;34(4):e216-e218. Epub 2017 May 23.
    Department of Pathology, University Hospital of Salamanca, Salamanca, Spain.
    Fibroblastic connective tissue nevus (FCTN) is a rare, benign, dermal mesenchymal hamartoma that affects children. We report a 15-year-old boy with a congenital FCTN and describe the clinical, dermatoscopic, and histopathologic features. Read More
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    Giant congenital melanocytic nevi: 40 years of experience with the serial excision technique.
    An Bras Dermatol 2017 Mar-Apr;92(2):256-259
    School of Medicine at Universidade de São Paulo (USP) - São Paulo (SP), Brazil.
    Although giant congenital melanocytic nevus is a rare lesion, it causes significant deformity and carries a risk of malignant degeneration. Different surgical techniques for the lesion removal are described, including serial resection, resection with skin grafting, and resection and coverage with expanded skin flap (skin expanders). The aim of this study is to report the author's 40 years of experience with cases requiring at least 4 serial excisions to complete the treatment. Read More
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    Proliferative nodule in melanocytic nevi mimicking deep penetrating nevus.
    An Bras Dermatol 2017 Mar-Apr;92(2):231-233
    Department of Dermatology, San Cecilio University Hospital - Granada, Spain.
    Proliferative nodules can occasionally arise on congenital and acquired melanocytic nevi. At first sight their clinical and pathologic features cause alert to both dermatologist and dermatopathologist. However, proliferative nodules are typically benign, regression is common and there is minimum risk of malignization. Read More
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    A prospective study of patients with large congenital melanocytic nevi and the risk of melanoma.
    An Bras Dermatol 2017 Mar-Apr;92(2):200-205
    Dermatology Unity - Hospital das Clinicas - Universidade Federal de Minas Gerais (UFMG) - Belo Horizonte (MG), Brazil.
    Background:: Large congenital melanocytic nevus (LCMN) is considered a risk factor for melanoma, although the magnitude of this risk is controversial.

    Objective:: To evaluate the risk of melanoma development in patients with LCMN seen at a dermatology referral center in Brazil during a twelve-year period. To the best of our knowledge, there are no published similar studies on large congenital melanocytic nevus in South America. Read More
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    Giant congenital melanocytic nevi and malignant transformation: a case for early radical intervention.
    Pediatr Surg Int 2017 Jul 15;33(7):823-827. Epub 2017 May 15.
    Centre for Children's Burns and Trauma Research, Lady Cilento Children's Hospital, Brisbane, Australia.
    The purpose of this paper is to highlight the risk of early malignant transformation in infants with giant congenital melanocytic nevi (GN) and demonstrate the potential for earlier intervention with aggressive surgery. We describe the case of a child born with a GN who developed a metastatic melanoma early in life, despite early commencement of resection of the nevus. This is contrasted against a second case of a child in which a more radical management was conducted. Read More
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    Overgrowth Syndromes Caused by Somatic Variants in the Phosphatidylinositol 3-Kinase/AKT/Mammalian Target of Rapamycin Pathway.
    J Mol Diagn 2017 Jul 11;19(4):487-497. Epub 2017 May 11.
    Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address:
    Somatic variants have been well described in tumorigenesis; however, they are only recently appreciated in other human disorders, such as mosaic overgrowth syndromes. Although overgrowth is a manifestation in many genetic syndromes, not all overgrowth syndromes are inherited. Mosaic somatic variants have been lately described in several overgrowth disorders, such as Proteus syndrome, CLOVES (congenital, lipomatous, overgrowth, vascular malformations, epidermal nevi, and spinal/skeletal anomalies and/or scoliosis) syndrome, and megalencephalyepolymicrogyria-polydactyly-hydrocephalus syndrome. Read More
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    Complications of Post-Burn Tissue Expansion Reconstruction: 9 Years Experience with 42 Pediatric and 26 Adult Patients.
    Isr Med Assoc J 2017 Feb;19(2):100-104
    Department of Plastic and Reconstructive Surgery.
    Background: Burn scar reconstruction is extremely challenging, even for the most proficient reconstructive surgeon. Within the arsenal of tools at the plastic surgeon's disposal, tissue expansion provides an efficient modality for reconstruction despite the reported complication rates.

    Objectives: To critically review our experience with tissue expansion for burn scar reconstruction, comparing particularly the adult and pediatric populations. Read More
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    ILVEN - COMPLETE REMISSION AFTER ADMINISTRATION OF TOPICAL CORTICOSTEROID (CASE REVIEW).
    Georgian Med News 2017 Feb(263):10-13
    Academic Teaching Hospital Dresden-Friedrichstadt, Department of Dermatology and Allergology; Medical Institute of Ministry of Interior (MVR), Department of Dermatology and Dermatologic Surgery, Sofia, Bulgaria.
    Inflammatory linear verrucous epidermal nevus (ILVEN) is a relatively rare disorder with an onset at early age, consisting of pruritic linear papules and/or plaques and histologic features resembling psoriasis or lichenoid dermatitis. The disease is a version of mosaicism caused by somatic mutations. ILVEN belongs to the heterogeneous group of congenital hamartomas of embryonal ectodermal origin, as a variant of verrucous epidermal nevus, representing approximately 5% of all epidermal nevi, with predominance in females and with general therapeutic resistance. Read More
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    Paediatric melanoma.
    J Eur Acad Dermatol Venereol 2017 Apr 27. Epub 2017 Apr 27.
    University Department of Dermatology - Venereology, "Andreas Sygros" Hospital, Athens, Greece.
    Paediatric melanoma, although rare, is the most common skin cancer in children. Our current knowledge on paediatric melanoma incidence trends is expanding, as several studies have addressed this issue with conflicting results. Known risk factors for paediatric melanoma include family history of melanoma, a previous history of malignancy, large congenital nevi, numerous melanocytic nevi, sunburns, increased UV exposure and a sun-sensitive phenotype. Read More
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    Quantification of Strain in a Porcine Model of Skin Expansion Using Multi-View Stereo and Isogeometric Kinematics.
    J Vis Exp 2017 Apr 16(122). Epub 2017 Apr 16.
    Division of Plastic Surgery, Ann and Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine.
    Tissue expansion is a popular technique in plastic and reconstructive surgery that grows skin in vivo for correction of large defects such as burns and giant congenital nevi. Despite its widespread use, planning and executing an expansion protocol is challenging due to the difficulty in measuring the deformation imposed at each inflation step and over the length of the procedure. Quantifying the deformation fields is crucial, as the distribution of stretch over time determines the rate and amount of skin grown at the end of the treatment. Read More
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    What's new with common genetic skin disorders?
    Minerva Pediatr 2017 Aug 20;69(4):288-297. Epub 2017 Apr 20.
    Department of Dermatology, Rochester, MN, USA -
    Familiar genetic disorders such as neurofibromatosis type I (NF1), tuberous sclerosis complex (TSC), oculocutaneous albinism (OCA), basal cell nevus syndrome (BCNS), incontinentia pigmenti, ichthyosis, and epidermolysis bullosa (EB) have prominent, cutaneous manifestations. This review describes recent advances in knowledge concerning the pathophysiology, diagnosis, and treatment of these skin features. Specifically, clinical diagnostic criteria for incontinentia pigmenti, ichthyosis, and tuberous sclerosis have been updated. Read More
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    Giant proliferating trichilemmal cyst arising from a nevus sebaceus growing for 30 years.
    J Cutan Pathol 2017 Apr 17. Epub 2017 Apr 17.
    Department of Pathology, Dermatopathology Division, Sylvester Comprehensive Cancer Center and Miller School of Medicine, University of Miami, Miami, Florida.
    Nevus sebaceus of Jadassohn, a congenital cutaneous hamartoma, has the potential to develop into various epidermal adnexal-origin neoplasms. While the most common neoplasms are trichoblastoma or syringocystadenoma, proliferating trichilemmal cysts are exceptionally rare. We report a case of a 63-year-old Cuban male with a giant proliferating trichilemmal cyst arising from a nevus sebaceus on the right shoulder which had been growing for 30 years. Read More
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    Evaluation and management of an unusual congenital nevus.
    Proc (Bayl Univ Med Cent) 2017 Apr;30(2):211-212
    Texas A&M College of Medicine (Kerwin, Menter), Baylor University Medical Center at Dallas (Menter), and Texas Dermatology Associates, P.A., Dallas, Texas (Menter).
    Abnormal findings on routine skin exams are common and can be a source of unnecessary medical workup if a clinician is unfamiliar with the finding. Sebaceous nevi are rare skin lesions that are most often benign but may be associated with a multiorgan syndrome or local skin cancer. Dermatologists and primary care physicians may encounter these on routine exams and thus must be comfortable with diagnosis and management. Read More
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    Proteus Syndrome with Arteriovenous Malformation.
    Adv Biomed Res 2017 7;6:27. Epub 2017 Mar 7.
    Department of Dermatology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
    Proteus syndrome is a rare sporadic disorder that appears with localized macrosomia, congenital lipomatosis, and slow flow vascular malformations, connective tissue nevus, and epidermal nevus. There are usually some manifestations at birth. The vascular abnormalities that have been reported in Proteus syndrome are capillary and slow flow venous malformation. Read More
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    Tissue expansion in the treatment of giant congenital melanocytic nevi of the upper extremity.
    Medicine (Baltimore) 2017 Mar;96(13):e6358
    aDepartment of Plastic Surgery bDepartment of Operating Theater, Henan Provincial People's Hospital, Zhengzhou City, Henan Province, China.
    The aim of our study was to use tissue expansion for the treatment of giant congenital melanocytic nevi of the upper extremity and examine potential advantages over traditional techniques.There were 3 stages in the treatment of giant congenital melanocytic nevi of the upper extremities using tissue expansion: first, the expander was inserted into the subcutaneous pocket; second, the expander was removed, lesions were excised, and the wound of the upper extremity was placed into the pocket to delay healing; third, the residual lesion was excised and the pedicle was removed. The pedicle flap was then unfolded to resurface the wound. Read More
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    Clinico-Dermoscopic Features of Spitz Naevi by Age and Anatomic Site: A Study of 378 Spitz Naevi.
    Br J Dermatol 2017 Mar 27. Epub 2017 Mar 27.
    Dermatology Unit, Second University of Naples, Naples, Italy.
    Spitz naevi (SN) are benign melanocytic naevi characterized by spindled and epithelioid cells in histology seen in both children and adults. In the present study, we aimed to determine whether there is a difference in the dermoscopic features of SN by age and anatomic site. Previous studies have demonstrated this association in congenital and common naevi. Read More
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    Giant benign intradermal melanocytic nevus of rapid onset.
    Dermatol Online J 2017 Feb 15;23(2). Epub 2017 Feb 15.
    Weill Cornell Medical College, New York, New York.
    Benign melanocytic nevi are slowly growing acquiredor congenital tumors with varied morphology,commonly encountered in dermatology clinics. Anytumor with rapid clinical growth must be assessedcarefully in order to exclude malignancy. We report awoman with a histopathologically benign intradermalnevus that presented as a rapidly evolving largecutaneous mass on the ear. Read More
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    Somatic PIK3CA mutations in seven patients with PIK3CA-related overgrowth spectrum.
    Am J Med Genet A 2017 Apr;173(4):978-984
    Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
    Somatic mutations in PIK3CA cause many overgrowth syndromes that have been recently coined the "PIK3CA-Related Overgrowth Spectrum." Here, we present seven molecularly confirmed patients with PIK3CA-Related Overgrowth Spectrum, including patients with Congenital Lipomatous Overgrowth, Vascular Malformations, Epidermal Nevi, Scoliosis/Skeletal and Spinal syndrome, Klippel-Trenaunay syndrome, lymphatic malformation and two with atypical phenotypes that cannot be classified into existing disease categories. The literature on PIK3CA-Related Overgrowth Spectrum, suggests that PIK3CA c. Read More
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    Patterns of distribution of giant congenital melanocytic nevi (GCMN): The 6B rule.
    J Am Acad Dermatol 2017 Apr;76(4):689-694
    Melanoma Unit, Department of Dermatology, Hospital Clinic of Barcelona, University of Barcelona, Barcelona, Spain; "Centro de Investigación Biomédica en Red en Enfermedades Raras, Instituto de Salud Carlos III", Barcelona, Spain. Electronic address:
    Background: Garment-related terms have been used to describe the pattern of distribution of giant congenital melanocytic nevi (GCMN).

    Objective: We sought to describe patterns of distribution of GCMN and propose a classification scheme.

    Methods: Photographic records of patients with GCMN from the Hospital Clinic of Barcelona were analyzed and a classification based on observed GCMN distribution patterns was created. Read More
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    Ocular Features in a Case of Nevus of Ota.
    J Coll Physicians Surg Pak 2017 Mar;27(3):S56-S57
    Department of Ophthalmology, Armed Forces Institute of Ophthalmology, Mall Road, Military Hospital, Rawalpindi.
    Oculodermal melanocytosis, also known as Nevus of Ota, is a hamartomatous melanocytic nevus of dermal melanocytes. It presents as a bluish grey patch on the face, which may be congenital or acquired involving the area of distribution of the ophthalmic and maxillary branches of the trigeminal nerve. The nevus can be unilateral or bilateral, and, in addition to skin, it may involve ocular and oral mucosal surfaces. Read More
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    Elastoma: clinical and histopathological aspects of a rare disease.
    An Bras Dermatol 2016 Sep-Oct;91(5 suppl 1):39-41
    Universidade Federal de São Paulo (Unifesp) - São Paulo (SP), Brazil.
    Elastoma is a connective tissue nevus characterized by changes in elastic fibers. It can be congenital or acquired, and is usually diagnosed before puberty. Associated with osteopoikilosis, it is known as Buschke-Ollendorff syndrome. Read More
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    Congenital melanocytic nevus on the lower eyelid treated with continuous wave and superpulsed CO2 laser followed by erbium laser.
    J Cosmet Laser Ther 2017 Aug 17;19(4):219-221. Epub 2017 Feb 17.
    a Private Practice , Abrusci Studio , Milan , Italy.
    There are several therapeutic options to treat congenital melanocytic nevi. The motivations for the treatment of small- to medium-sized congenital nevi located on the face or other sensitive areas are frequently cosmetic. The choice of therapy depends on the operator's expertise and on the likelihood of improved cosmesis. Read More
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    Melanoma and melanocytic nevi in paediatric patients: a single institution experience.
    G Ital Dermatol Venereol 2017 Mar 14. Epub 2017 Mar 14.
    Unità Operativa di Dermatologia, Dipartimento di Medicina Specialistica, Diagnostica e Sperimentale, Policlinico Sant'Orsola-Malpighi, Università di Bologna, Bologna, Italy.
    Background: Melanoma is an infrequent neoplasm in children and adolescents. The number of consultancies for melanocytic nevi control in the paediatric population is increased by the major anxiety of parents and paediatricians.

    Methods: A retrospective chart review was performed in order to evaluate the incidence rate of melanoma, Spitz nevi, congenital and acquired melanocytic nevi in patients aged 14 years or less and referred to our institution from April 2010 to September 2015. Read More
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    Mass Spectrometry Imaging Can Distinguish on a Proteomic Level Between Proliferative Nodules Within a Benign Congenital Nevus and Malignant Melanoma.
    Am J Dermatopathol 2017 Feb 20. Epub 2017 Feb 20.
    *Department of Dermatology, Yale University School of Medicine, New Haven, CT; †Smilow Cancer Center, New Haven, CT; ‡Department of Plastic Surgery, Plastic Surgery Hospital, Peking Union Medical College and the Chinese Academy of Medical Science, Beijing, China; §Department of Dermatology, School of Medicine, University of Balamand, Beirut, Lebanon; ¶Department of Genetics, Yale School of Medicine, New Haven, CT; ‖Protea Biosciences, Inc, Morgantown, WV; and **Mass Spectrometry Research Center, Vanderbilt University, Nashville, TN.
    Histopathological interpretation of proliferative nodules occurring in association with congenital melanocytic nevi can be very challenging due to their similarities with congenital malignant melanoma and malignant melanoma arising in association with congenital nevi. We hereby report a diagnostically challenging case of congenital melanocytic nevus with proliferative nodules and ulcerations, which was originally misdiagnosed as congenital malignant melanoma. Subsequent histopathological examination in consultation by one of the authors (R. Read More
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    Congenital melanocytic nevi in young children: Histopathologic features and clinical outcomes.
    J Am Acad Dermatol 2017 May 24;76(5):941-947. Epub 2017 Feb 24.
    Department of Pathology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts. Electronic address:
    Background: Although only large congenital melanocytic nevi (CMN) are associated with a significantly high risk for malignant transformation, CMN of all sizes are prone to changes in clinical appearance in early childhood and thus are often biopsied or excised. While CMNs typically exhibit benign behavior, atypical histopathologic findings might be common and may prompt additional unnecessary procedures.

    Objective: To assess the prevalence and associated clinical outcomes of atypical histopathologic features in CMN in children. Read More
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    "Sky Full of Stars" Pattern: Dermoscopic Findings in a Desmoplastic Giant Congenital Melanocytic Nevus.
    Pediatr Dermatol 2017 May 27;34(3):e142-e143. Epub 2017 Feb 27.
    Department of Dermatology, Hospital Universitario Virgen del Rocio, Sevilla, Spain.
    Desmoplastic giant congenital melanocytic nevus (DGCN) is an uncommon variant of congenital nevus, presenting as a progressive induration and hypopigmentation of the lesion that occasionally causes hair loss and even total or partial disappearance of the nevus. A 6-month-old girl with a giant congenital melanocytic nevus that involved the entire posterior side of the right thigh was seen in our department. Nine months later, the peripheral area of the nevus presented as a marked induration with hypopigmentation. Read More
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    Dermoscopic Findings of Scalp Aplasia Cutis Congenita.
    Skin Appendage Disord 2017 Jan 8;2(3-4):177-179. Epub 2016 Dec 8.
    Hair and Scalp Diseases, Outpatient Clinic, Division of Dermatology, Santa Casa de Misericórdia, Porto Alegre, Brazil.
    Aplasia cutis congenita (ACC) is a rare disease characterized by congenital absence of skin, affecting preferentially the scalp. Diagnosis is made clinically; however, recent studies have shown that dermoscopy can be a useful tool for the diagnosis and differentiation from sebaceous nevus. The clinical findings include a shiny atrophic alopecic patch associated with dermoscopic findings of absent follicular openings, thicker vessels and a distinct collar hypertrichosis. Read More
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    Intense Pulsed Light Alone and in Combination with Erbium Yttrium-Aluminum-Garnet Laser on Small-to-Medium Sized Congenital Melanocytic Nevi: Single Center Experience Based on Retrospective Chart Review.
    Ann Dermatol 2017 Feb 3;29(1):39-47. Epub 2017 Feb 3.
    Department of Dermatology, Incheon St. Mary's Hospital, Incheon, Korea.
    Background: Treatment of congenital melanocytic nevi (CMN) with intense pulsed light (IPL) has recently produced promising results.

    Objective: To evaluate the clinical and histological outcomes of small-to-medium sized CMN treated with IPL alone and in combination with erbium: yttrium-aluminum-garnet (Er: YAG) laser.

    Methods: We performed a retrospective chart review of 26 small-to-medium sized CMN treated as described above. Read More
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    Dermoscopic Features of Small, Medium, and Large-Sized Congenital Melanocytic Nevi.
    Ann Dermatol 2017 Feb 3;29(1):26-32. Epub 2017 Feb 3.
    Department of Dermatology, Bezmialem Vakif University, Istanbul, Turkey.
    Background: Congenital melanocytic nevi (CMN) are present at birth. It is well known that the presence of large-sized congenital nevus in early life could predict a major risk of developing melanoma.

    Objective: To investigate the clinical and dermoscopic features of the CMN, to search for and highlight any differences between small-sized, medium-sized, large-sized CMN. Read More
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    Clinical course, treatment modalities, and quality of life in patients with congenital melanocytic nevi - data from the German CMN registry.
    J Dtsch Dermatol Ges 2017 Feb;15(2):159-167
    Department of Dermatology, University of Lübeck, Germany.
    Background: Congenital melanocytic nevi (CMN) are associated with mental stress as well as medical risks for those affected. The German CMN registry was initiated in 2005. Herein, we present results from an interim analysis focusing on disease course, treatment modalities, and quality of life. Read More
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