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Mol Syndromol 2021 Apr 1;12(2):112-117. Epub 2021 Feb 1.

Department of Medical Genetics, AGENTEM, Cukurova University Faculty of Medicine, Adana, Turkey.

Camptodactyly-arthropathy-coxa vara-pericarditis (CACP) syndrome, caused by biallelic pathogenic mutations in the gene, is characterized by early-onset camptodactyly, noninflammatory arthropathy, coxa vara deformity, and rarely, pericardial effusion. Herein, we report 3 patients with CACP syndrome from 2 unrelated families. All patients are female, born to consanguineous parents, and had camptodactyly since the first years of their lives. Read More

J Orthop Surg Res 2021 Apr 29;16(1):285. Epub 2021 Apr 29.

Department of Orthopedics Trauma, Xi'an Honghui Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an, 710054, P.R. China.

Background: To investigate the clinical efficacy of locking compression plate fixation for the treatment of femoral intertrochanteric fractures in patients with preexisting proximal femoral deformity.

Methods: A retrospective analysis was conducted on 37 patients with femoral intertrochanteric fractures combined with preexisting proximal femoral deformity between January 2013 and July 2019. The patients included 24 males and 13 females aged from 23 to 69 years old, with an average age of 47. Read More

Medicine (Baltimore) 2021 Mar;100(12):e25274

Shuangliu District First People's Hospital, Chengdu, China.

Abstract: To investigate the influencing factors of fracture nonunion after intramedullary nailing for subtrochanteric fractures and to construct a risk assessment model.Based on the multicenter retrospective analysis of 251 patients, all patients were divided into modeling group and verification group. In the modeling group, postoperative fracture nonunion rate, general data, fracture-related factors, surgical reduction-related factors, mechanical and biological factors were calculated, and the influencing factors of fracture nonunion were screened by univariate analysis. Read More

Eur J Med Genet 2021 Apr 2;64(4):104185. Epub 2021 Mar 2.

Department of Pediatric Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey. Electronic address:

Musculoskeletal symptoms may be due to noninflammatory causes, including genetic disorders. We aimed to examine the final genetic diagnosis in patients who presented with musculoskeletal complaints to the rheumatology department. Patients who presented to the Department of Pediatric Rheumatology and were referred to the pediatric genetic department between January 2015 and May 2019 were evaluated retrospectively. Read More

Indian J Orthop 2021 Feb 13;55(1):81-92. Epub 2021 Jan 13.

Paras HMRI Hospital, Raza Bazaar, Patna, Bihar 800014 India.

Background: Ipsilateral femoral neck with shaft fracture (IFNSF) in the paediatric population is a rare injury. This high-impact trauma is often associated with other orthopaedic and systemic injuries. Prognosis is usually guarded as both these osseous injuries are serious and exist together. Read More

Indian J Orthop 2021 Feb 18;55(1):23-34. Epub 2020 Sep 18.

Department of Paediatric Orthopaedics, Bai Jerbai Wadia Hospital for Children, Acharya Donde Marg, Parel, Mumbai, Maharashtra 400012 India.

Background: Femoral neck fractures in children are rare injuries, occurring due to high-energy trauma. Due to the unique anatomy and blood supply of the proximal femur in growing children, these fractures are notorious for high rates of complications despite appropriate management. Classification of these fractures is according to the Delbet system, which not only guides management but also gives prognostic clues. Read More

Medicine (Baltimore) 2021 Jan;100(4):e23616

Department of Orthopaedic Surgery, Lishui Hospital, Zhejiang University School of Medicine, The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui Municipal Central Hospital, Lishui, Zhejiang, People's Republic of China.

Rationale: Pediatric femoral shaft combined with ipsilateral femoral neck fractures are very rare but challenging injuries fraught with the development of avascular necrosis, coxa vara, and leg length discrepancy. Majority of the previous reports indicated the neck femur fracture was fixed with cannulated screws or/and pins, femoral shaft fracture was stabilized with a plate and screws. However, we used cannulated screws combined with elastic stable intramedullary nails to minimally invasive procedures treat this type of injury and achieved good follow-up results. Read More

Oper Orthop Traumatol 2021 Feb 19;33(1):23-35. Epub 2021 Jan 19.

Kindertraumatologie, BG Unfallklinik Murnau, Prof.-Küntscher-Str. 8, 82418, Murnau am Staffelsee, Deutschland.

Objective: Anatomic reduction and stable fixation of pediatric femoral neck fractures.

Indications: All unstable and displaced femoral neck fractures (AO classification 31-E/1.1, 31-E/1. Read More

Malays Orthop J 2020 Nov;14(3):98-103

Department of Orthopaedics, Saveetha University Saveetha Medical College and Hospital, Kanchipuram, India.

Introduction: Malunited intertrochanteric fractures are frequently seen in rural populations as they tend to go in for native treatment with traditional bone setters. The resulting Coxa vara is associated with shortening, abductor weakness, limp and decreased range of movement of the affected hip. The aim of this study was to evaluate the role of Valgus osteotomy with Dynamic hip screw (DHS) fixation in the management of these fractures and to evaluate the functional outcome using the Harris hip score. Read More

J Int Med Res 2020 Dec;48(12):300060520950934

Department of Orthopaedic Surgery, Affiliated Huizhou Central People Hospital, Sun Yat-Sen University and Guangdong Medical University, Huizhou City, Guangdong Province, People's Republic of China.

Background: Femoral head collapse and coxa vara lead to internal fixator failure in elderly patients with hip fracture. External fixator application is an optimal choice; however, the existing methods have many disadvantages.

Methods: Type 31-A1. Read More

Osteoarthritis Cartilage 2021 05 15;29(5):607-618. Epub 2020 Dec 15.

Department of Orthopedics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.

Objective: To summarize available evidence on the association between hip shape as quantified by statistical shape modeling (SSM) and the incidence or progression of hip osteoarthritis.

Design: We conducted a systematic search of five electronic databases, based on a registered protocol (available: PROSPERO CRD42020145411). Articles presenting original data on the longitudinal relationship between radiographic hip shape (quantified by SSM) and hip OA were eligible. Read More

Cureus 2020 Nov 13;12(11):e11478. Epub 2020 Nov 13.

Department of Orthopaedics, Max Super Speciality Hospital, Patparganj, New Delhi, IND.

Femoral neck stress fractures in middle-aged individuals are usually associated with underlying metabolic bone disease. There is increased abnormal loading on femoral neck with associated coxa-vara and obesity in a female. Bilateral presentation of such fractures is rarely reported. Read More

BMJ Case Rep 2020 Dec 13;13(12). Epub 2020 Dec 13.

Department of Orthopaedics, University College of Medical Sciences, New Delhi, Delhi, India.

The treatment of pathological femoral neck fracture in children due to osteopetrosis is not clear as only a few cases have been reported to date. We encountered a 7-year-old osteopetrotic girl with asynchronous bilateral femoral neck fractures. Radiographical assessment showed markedly dense bones with loss of corticomedullary differentiation, sandwich vertebrae and increased density of the ribs. Read More

Skeletal Radiol 2021 Jun 3;50(6):1163-1168. Epub 2020 Nov 3.

Department of Radiology, The Armed Forces Capital Hospital, 81 Saemaeul-ro 177 beon-gil, Bundang-gu, Seongnam, 13574, South Korea.

Objective: To evaluate the influences of the femoral neck shaft angle (FNSA) on the location of the femoral stress fracture and to assess the potential differences in FNSA between fractured and normal femurs.

Materials And Methods: Thirty-seven patients with femoral stress fractures who underwent both plain hip radiographs and MRI, from January 2016 to September 2019, were retrospectively included. Patients were classified as having either femoral head stress fracture (group A, n = 26) or femoral neck stress fracture (group B, n = 11). Read More

J Clin Orthop Trauma 2020 Oct 30;11(Suppl 5):S799-S806. Epub 2020 May 30.

Department of Orthopaedics, Christian Medical College and Hospital, Brown Road, Ludhiana, Punjab. PIN 141008, India.

Paediatric femur neck fracture is an uncommon injury and is known for high rate of complications. This in turn, can have significant impact on development of hip and overall function of the child. Controversy prevails in many areas of management and it still remains a difficult injury to manage. Read More

Orthopade 2020 Oct;49(10):929-940

Klinik für Orthopädie, Klinikum Stuttgart, Olgahospital, Kriegsbergstr. 62, 70176, Stuttgart, Deutschland.

Fibrous dysplasia is a benign intraosseous tumor, which can occur as a monostotic or polyostotic disease. As a combination of dermatological and endocrinological features it is known as McCune-Albright syndrome, in conjunction with intramuscular myxoma as Mazabraud's syndrome. Fibrous dysplasia originates from a genetic defect, a postzygotic mutation of the GNAS gene, leading to incorrect regulation of the osteogenesis of the affected area of the bone. Read More

Rheumatol Int 2020 Aug 19. Epub 2020 Aug 19.

Allergy Immunology Unit, Department of Pediatrics, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India.

Camptodactyly-arthropathy-coxa vara-pericarditis (CACP) syndrome is a rare familial arthropathy of childhood, commonly misdiagnosed as juvenile idiopathic arthritis. It is characterized by non-inflammatory arthropathy, coxa vara deformity, and sterile pericarditis. We describe two children with CACP syndrome who were referred to the rheumatology clinic for the suspicion of inflammatory arthritis. Read More

Am J Transl Res 2020 15;12(7):3917-3925. Epub 2020 Jul 15.

Department of Bone and Joint, Shenzhen People's Hospital, The First Affiliated Hospital of Nanfan University of Science and Technology, The Second Clinical Medical College of Jinan University Shenzhen 518020, Guangdong, P. R. China.

Objective: In this study, a new type of reduction device for femoral shaft fractures was developed and designed. The reduction procedure was also standardized and is expected to be useful in clinical practice.

Methods: A bone traction retractor that consisted of a special traction needle, a resistant sleeve, a crossbar and an arc-adjusting bar was designed. Read More

Bone Joint J 2020 Aug;102-B(8):1048-1055

Bristol Royal Hospital for Children, Bristol, UK.

Aims: The Fassier Duval (FD) rod is a third-generation telescopic implant for children with osteogenesis imperfecta (OI). Threaded fixation enables proximal insertion without opening the knee or ankle joint. We have reviewed our combined two-centre experience with this implant. Read More

SICOT J 2020 16;6:28. Epub 2020 Jul 16.

Head of Musculoskeletal Tumor Surgery Unit, Children Cancer Hospital-Egypt (57357), 11617 Cairo, Egypt - Lecturer, Department of Orthopedic Surgery, Faculty of Medicine, Cairo University, 12613 Giza, Egypt.

Introduction: Skeletal involvement in children with Langerhans cell histiocytosis (LCH) is a common feature of the disease. Several options for the treatment of these skeletal lesions have been reported. We describe our experience in the treatment of skeletal involvement of LCH in this retrospective case series study, entailing anatomic distribution, pattern of healing, skeletal deformities, and functional outcome of skeletal LCH. Read More

Clin Orthop Surg 2020 Jun 14;12(2):258-262. Epub 2020 May 14.

Department of Orthopedic Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.

The mainstream surgery for valgus-impacted femoral neck fractures (FNFs) is closed reduction and internal fixation under fluoroscopy. However, femoral neck shortening and anterior femoroacetabular impingement are common complications in healed valgus-impacted FNFs after fixation. Some methods have been reported to prevent complications, but these techniques require the use of a transfixing guide wire that passes through the femoral head, which may cause articular cartilage damage. Read More

Arch Orthop Trauma Surg 2021 Jun 30;141(6):891-897. Epub 2020 May 30.

Gelenkzentrum Bergisch Land, Freiheitstraße 203, 42853, Remscheid, Germany.

Introduction: Inaccurate stem implantation can cause unsatisfactory offset reconstruction and may result in insufficient gluteal muscle function or aseptic loosening. In this study, stem alignment of a collarless straight tapered HA-coated stem was retrospectively analyzed during the learning phase of the direct anterior approach (DAA) for primary total hip arthroplasty (THA).

Material And Methods: From Jan 2013 to Jun 2015, a total of 93 cementless THA were implanted in patients with unilateral coxarthrosis via the DAA in a two surgeon setting using the Corail or Trendhip stem (DePuy Synthes or Aesculap). Read More

J Orthop Surg (Hong Kong) 2020 Jan-Apr;28(2):2309499020926268

Department of Orthopaedic Surgery, College of Medicine, Daegu Catholic University Hospital, Daegu, Korea.

Purpose: We have analyzed the surgical outcomes of primary total knee arthroplasty (TKA) using computer-assisted navigation that were performed by a single surgeon in terms of postoperative coronal alignment depending on preoperative varus deformity.

Methods: We conducted a retrospective study of patients who have undergone navigated primary TKA from January 2016 through December 2019. Two hundred and fifty-six cases with varus deformity of 10° or less were assigned to group 1, and 216 cases with varus deformity of more than 10° were assigned to group 2. Read More

J Orthop Surg (Hong Kong) 2020 Jan-Apr;28(2):2309499020924600

Department of Orthopedics, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand.

Purpose: Multiple needle punctures (MNPs), for gap balancing in total knee replacement, have less variability in gap widening compared to the conventional released technique. This study aimed to evaluate the outcome of gap-balancing techniques in varus osteoarthritis (OA) knees, by serial MNP, after a total knee prosthesis trial component was placed, combined with repetitive knee manipulation.

Methods: This study was a retrospective, case-matched study of 161 patients. Read More

J Orthop 2020 Nov-Dec;22:207-212. Epub 2020 May 6.

Department of Orthopaedics, Kasturba Hospital, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, India.

Objectives: Pediatric femoral neck fractures were reviewed to compare complications with the time of presentation.

Methods: 34 pediatric femoral neck fractures were studied to detect union time, avascular necrosis, premature physis fusion, and the neck-shaft angle. All complications were comparable between both groups. Read More

Pediatr Radiol 2020 07 2;50(8):1115-1122. Epub 2020 May 2.

Child and Adolescent Protection Center, Children's National Hospital, Washington, DC, USA.

Background: Proximal femoral physeal fractures are rare in abused children. Recognition may be hampered due to their rarity and lack of an ossified femoral head. Prompt diagnosis and treatment are essential to preventing coxa vara. Read More

Cureus 2020 Mar 23;12(3):e7371. Epub 2020 Mar 23.

Pediatrics, Civil Hospital Karachi, Dow University of Health Sciences, Karachi, PAK.

Metaphyseal chondrodysplasia, Schmid type (MDSC) is a rare inherited autosomal disorder with characteristic skeletal deformities striking on radiological imaging, which includes metaphyseal cupping and fraying. Physical examination reveals short stature in early childhood, frontoparietal bossing, rachitic rosary, genu varum and valgum, and coxa vara usually. We believe that the constellation of clinical and radiographic findings of MDSC might look similar to vitamin D resistant rickets; hence, genetic analysis is needed to overcome diagnostic challenges faced by physicians to avoid unnecessary vitamin D supplementation in individuals. Read More

Indian J Orthop 2020 Feb 31;54(1):83-86. Epub 2020 Jan 31.

Department of Orthopaedics, Ganga Hospital, 313, Mettupalayam road, Coimbatore, 641043 Tamil Nadu India.

Bilateral Femoral neck stress fractures (FNSFs) are rare without any underlying metabolic disease or repeated strenuous activities like athletes or military recruits. It constitutes about 5-8% of all stress fractures. Treatment options are still controversial. Read More

Eur J Orthop Surg Traumatol 2020 Aug 6;30(6):1039-1044. Epub 2020 Apr 6.

The Royal London Hospital, Barts Health NHS Trust, Whitechapel Road, London, E1 1BB, UK.

Aims: The safety and efficacy of tranexamic acid (TXA) in reducing blood loss after total joint arthroplasty and spinal fusion surgery has been well documented. However, little data exist regarding the effectiveness of intraoperative TXA in children with cerebral palsy (CP). The aim of this double cohort study is to investigate the safety and efficacy of intraoperative TXA in reducing blood loss and transfusion requirements for children with CP undergoing a proximal unilateral or bilateral femoral varus derotational osteotomy (VDRO). Read More