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Orthopade 2019 Apr 17. Epub 2019 Apr 17.

Orthopädische Klinik, Olgahospital, Klinikum Stuttgart, Kriegsbergstr. 62, 70174, Stuttgart, Deutschland.

In slipped capital femoral epiphysis (SCFE) atypical causes can be found in about 5% of cases. The patients' age differs from the typical age of SCFE patients of between age 10 and 16. There are numerous causes of atypical SCFE: different endocrine disorders, sequelae of chronic renal failure and effects of radiation and chemotherapy on the proximal femoral physis. Read More

Am J Hum Genet 2019 Mar 14;104(3):422-438. Epub 2019 Feb 14.

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Texas Children's Hospital, Houston, TX 77030, USA. Electronic address:

SPONASTRIME dysplasia is an autosomal-recessive spondyloepimetaphyseal dysplasia characterized by spine (spondylar) abnormalities, midface hypoplasia with a depressed nasal bridge, metaphyseal striations, and disproportionate short stature. Scoliosis, coxa vara, childhood cataracts, short dental roots, and hypogammaglobulinemia have also been reported in this disorder. Although an autosomal-recessive inheritance pattern has been hypothesized, pathogenic variants in a specific gene have not been discovered in individuals with SPONASTRIME dysplasia. Read More

Medicine (Baltimore) 2019 Jan;98(1):e13780

Department of Medical Chemistry, Medical University of Vienna, Vienna, Austria.

Spondyloepiphyseal dysplasia congenita (SEDC) is an autosomal dominant disorder, characterized by disproportionate dwarfism with short spine, short neck associated with variable degrees of coxa vara. Cervical cord compression is the most hazardous skeletal deformity in patients with SEDC which requires special attention and management.Ten patients with the clinical and the radiographic phenotypes of spondyloepiphyseal dysplasia congenita have been recognized and the genotype was compatible with single base substitutions, deletions or duplication of part of the COL2A1 gene (6 patients out of ten have been sequenced). Read More

Bone 2019 Apr 30;121:163-171. Epub 2018 Dec 30.

CHU Sainte Justine Research Centre and Department of Pediatrics, University of Montreal, Montreal, QC H3T 1C5, Canada. Electronic address:

Heterozygous pathogenic variants in the FN1 gene, encoding fibronectin (FN), have recently been shown to be associated with a skeletal disorder in some individuals affected by spondylometaphyseal dysplasia with "corner fractures" (SMD-CF). The most striking feature characterizing SMD-CF is irregularly shaped metaphyses giving the appearance of "corner fractures". An array of secondary features, including developmental coxa vara, ovoid vertebral bodies and severe scoliosis, may also be present. Read More

J Orthop Case Rep 2018 May-Jun;8(3):33-37

Department of Orthopaedics, Sri Ramachandra Medical University, Chennai, Tamil Nadu, India.

Introduction: Fibrous dysplasia is a rare benign disorder of the skeletal system characterized by fibro-osseous proliferation with intervening areas of normal or immature bone in the intramedullary region. It can either be a monostotic (involves one bone) or a polyostotic (involves more than one bone) presentation and usually occurs equally in males and females. Deformities such as scoliosis and shepherd's crook deformity are frequently encountered in the polyostotic form. Read More

Indian J Orthop 2018 Sep-Oct;52(5):501-506

Department of Orthopaedics, Christian Medical College, Vellore, Tamil Nadu, India.

Paediatric femoral neck fractures are uncommon injuries and are usually caused by high-energy trauma. Low-energy trauma can result in pathologic neck fractures and stress fractures of the neck, due to repetitive activity. Surgical options can vary based on age, Delbet classification and displacement of the fracture. Read More

Oper Orthop Traumatol 2018 Oct 8;30(5):379-386. Epub 2018 Aug 8.

Klinik und Poliklinik für Orthopädie und Unfallchirurgie, Universitätsklinikum Bonn, Sigmund-Freud-Str. 25, 53105, Bonn, Deutschland.

Objective: Growth disorders (e. g. caused by congenital hip dislocation, Perthes disease or bacterial coxitis) often lead to an infantile deformity of the proximal femur with a shortened femoral neck and displaced grater trochanter. Read More

Am J Med Genet A 2018 Sep 31;176(9):2009-2016. Epub 2018 Jul 31.

Division of Pediatric Genetics, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey.

Our understanding of the molecular basis of the genetic disorders of the skeleton has steadily increased, as the application of high-throughput sequencing technology has expanded. One of the newcomers is Spondyloepimetaphyseal dysplasia Faden-Alkuraya type. In this study, we aimed to further delineate the clinical, radiographic, and molecular findings of this entity in five affected individuals from two unrelated families. Read More

Orthop Surg 2018 Aug 19;10(3):241-246. Epub 2018 Jul 19.

Institute of Medical Chemistry, Medical University of Vienna, Austria.

Objectives: There are several types of metaphyseal chondrodysplasia and various clinical types have been differentiated. The Schmid type of metaphyseal chondrodysplasia is the most common. Diffuse metaphyseal flaring, irregularity, and growth plate widening, which are most severe in the knees, are the most striking radiological features of this disease. Read More

Knee 2018 Oct 17;25(5):825-833. Epub 2018 Jul 17.

Funktionsbereich Bewegungsanalytik, IEMM, Universitätsklinikum Münster, Albert-Schweitzer Campus 1, Gebäude D3, 48129 Münster, Germany.

Background: Knee osteoarthritis (KOA) is the most common form of arthritis with an estimated lifetime prevalence of 45%. The use of orthotic devices is a generally accepted conservative therapy in KOA. A new conservative treatment is an ankle-foot orthosis (AFO); however, studies on the biomechanical effects are limited. Read More

Eur Rev Med Pharmacol Sci 2018 Jul;22(1 Suppl):1-7

Department of Orthopedic, Renmin Hospital of Wuhan University, Wuhan, China.

Objective: This study sought to compare the effects of proximal femoral nail anti-rotation (PFNA) and dynamic hip screw (DHS) helical blade treatments in patients with osteoporotic femoral intertrochanteric fractures.

Patients And Methods: Eighty elderly osteoporosis patients with femoral intertrochanteric fracture complications admitted to the hospital between January 2013 and December 2014 were selected and divided into control (n=40) and observation (n=40) groups. The control group received DHS internal fixation while the observation group received PFNA treatment. Read More

Oper Orthop Traumatol 2018 Oct 15;30(5):359-368. Epub 2018 Jun 15.

Clinic for Orthopedics and Trauma Surgery, University of Bonn, Bonn, Germany.

Objective: Presenting the implantation of the PediatrOS™ FlexTack™ (Merete, Berlin, Germany) for growth guidance and a modified explantation procedure to facilitate explantation and prevent bone and soft tissue damage.

Indications: Implantation: Genua vara and valga, coxa vara, varus and valgus deviation of the ankle joint, the elbow joint and the wrist Modified Explantation: Removal of the implant after successful limb correction or dislocation of the implant.

Contraindications: Implantation: Closed growth plates, insufficient remaining growth potential, acute or chronic infection, insufficient osseous structures, severe muscular, nervous or vessel diseases endangering the respective limb Explantation: General inoperability of the patient. Read More

J Am Acad Orthop Surg 2018 Jun;26(12):411-419

From the Department of Orthopaedic Surgery, University of California, San Francisco, CA.

In the pediatric population, femoral neck fracture is a relatively uncommon injury with a high complication rate, despite appropriate diagnosis and management. The anatomy and blood supply of the proximal femur in the skeletally immature patient differs from that in the adult patient. Generally, these fractures result from high-energy trauma and are categorized using the Delbet classification system. Read More

Hip Int 2019 Mar 9;29(2):134-140. Epub 2018 May 9.

3 Department of Orthopaedic Surgery, Seoul National University Bundang Hospital, Seongnam, South Korea.

Introduction:: Pseudosubluxation is a transient separation of the prosthetic femoral head from the acetabular liner during the anaesthetic period after total hip arthroplasty (THA). However, little is known about the frequency, pathomechanism, risk factors or natural history.

Methods:: To determine the incidence, direction of the displacement, risk factors and subsequent instability of pseudosubluxation, we evaluated 1099 primary cementless THAs (943 patients), which were performed during 8 years at one institution. Read More

J Arthroplasty 2018 08 30;33(8):2512-2517. Epub 2018 Mar 30.

Department of Orthopedic Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.

Background: Patients with severe preoperative varus deformity have been reported to have high rates of loosening after total knee arthroplasty (TKA), primarily on the tibial side. This study investigated whether a short extension stem for the tibial component in severely varus knees would reduce the failure rate due to loosening on the tibial side.

Methods: Patients who underwent TKA, performed by a single surgeon using a single implant between November 1998 and January 2009, were retrospectively evaluated. Read More

Clin Orthop Relat Res 2018 Jul;476(7):1479-1490

R. K. Kanojia, S. Gupta, Department of Orthopaedics, Lady Hardinge Medical College and Associated Hospitals, New Delhi, India A. Kumar, Department of Paediatrics and Neonatology, Lady Hardinge Medical College and Associated Hospitals, New Delhi, India B. K. Reddy, Department of Orthopaedics, Ashwini Hospital CDA Sector 1, Cuttack, Orissa, India.

Background: When treatment of acute septic arthritis of the hip is delayed, severe sequelae can occur. This may take the form of coxa breva, vara, or valga. Pseudoarthrosis of the femoral neck is a rare complication with only a few studies to guide treatment. Read More

J Orthop 2018 Jun 5;15(2):529-535. Epub 2018 Apr 5.

Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC, USA.

Pediatric proximal femur fractures are rare injuries resulting from high-energy trauma. The Delbet classification is used when describing these injuries, and associates fracture type to the development of avascular necrosis. Historically, casting was utilized in the treatment of these injuries, but high complication rates following this approach have changed the treatment modality to early and anatomic fixation. Read More

Gait Posture 2018 05 26;62:297-302. Epub 2018 Mar 26.

Institut für Experimentelle Muskuloskelettale Medizin (IEMM), Universitätsklinikum Münster (UKM), Westfälische Wilhelms-Universität Münster (WWU), Münster, Germany; Otto Bock Healthcare GmbH, Göttingen, Germany. Electronic address:

Background: Knee osteoarthritis (KOA) is a painful disease commonly caused by high loads on the articular cartilage. Orthotic interventions aim to reduce mechanical loading, thereby alleviating pain. Traditional orthotics appear effective, but high drop-out rates have been reported over prolonged periods. Read More

Mol Genet Genomic Med 2018 03 4;6(2):230-248. Epub 2018 Feb 4.

Department of Pediatric Genetics, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey.

Background: The camptodactyly-arthropathy-coxa vara-pericarditis syndrome (CACP) is a rare autosomal recessive condition characterized by camptodactyly, noninflammatory arthropathy, coxa vara, and pericarditis. CACP is caused by mutations in the proteoglycan 4 (PRG4) gene, which encodes a lubricating glycoprotein present in the synovial fluid and at the surface of articular cartilage.

Methods: In the present study, we compared the clinical and molecular findings of CACP syndrome in 35 patients from 11 unrelated families. Read More

Zhongguo Gu Shang 2017 Mar;30(3):256-260

Traditional Chinese Medical Hospital of Xiaoshan, Hangzhou 311201, Zhejiang, China.

Objective: To retrospectively study medium term follow-up outcomes of the femoral intertrochanteric with lateral femoral wall fractures using anatomic locking plate fixation.

Methods: From June 2010 to January 2013, 18 cases of the unstable femoral intertrochanteric with lateral femoral wall fractures were treated with the anatomic locking plate, included 8 males and 10 females with an average age of 75.5 years ranging from 19 to 83 years old. Read More

J Hip Preserv Surg 2017 Dec 23;4(4):269-275. Epub 2017 Aug 23.

Clinica Orthopedica, Ospedale di Portogruaro, 30026 Portogruaro, Italy.

Proximal femoral fracture and coxarthrosis are the most common orthopaedic problems of osteopetrosis. Fracture fixation is difficult and one-third fail, with total hip replacement as the final solution. There is little reported experience about how to deal with this particular type of bone and what has been published to date is surprisingly non-specific. Read More

Rofo 2018 Sep 20;190(9):856-858. Epub 2017 Nov 20.

Diagnostic and interventional radiology, University of Jordan, Amman, Jordan.

Am J Hum Genet 2017 Nov;101(5):815-823

Centre Hospitalier Universitaire Sainte Justine Research Centre, University of Montreal, Montreal, QC H3T 1C5, Canada. Electronic address:

Fibronectin is a master organizer of extracellular matrices (ECMs) and promotes the assembly of collagens, fibrillin-1, and other proteins. It is also known to play roles in skeletal tissues through its secretion by osteoblasts, chondrocytes, and mesenchymal cells. Spondylometaphyseal dysplasias (SMDs) comprise a diverse group of skeletal dysplasias and often manifest as short stature, growth-plate irregularities, and vertebral anomalies, such as scoliosis. Read More

J Clin Orthop Trauma 2017 Oct-Dec;8(4):308-312. Epub 2016 Nov 21.

Department of Orthopaedics, Smt. Bhikhiben Kanjibhai Shah Medical Institute & Research Centre, Sumandeep Vidyapeeth, Vadodara, Gujarat, India.

Introduction: Pertrochanteric fractures are most frequent factures of the proximal femur, accounts for nearly 50% of all proximal femur fractures and are most devastating and also a major cause of disability in elderly. The aim and objective of this study was to evaluate the role of proximal femoral locking compression plate in unstable proximal femur fractures.

Material And Method: A total of 20 cases were included in our study (M:F - 16:4), who suffered proximal femur fracture due to various modalities and all of them were operated using proximal femoral locking compression plate. Read More

Malays Orthop J 2017 Jul;11(2):82-84

Department of Orthopaedics, Universiti Sains Malaysia, Kubang Kerian, Malaysia.

The ideal size of intramedullary device to fix corrective osteotomy of proximal femur in abnormal bone in children and small patients may not be easily available. We report the successful use of Rush rod in combination with multiple Kirschner wires to fix the corrective osteotomy of coxa vara and shepherd crook deformity in two patients with osteogenesis imperfecta and fibrous dysplasia. The union was achieved on time, neck shaft angle and rotation were maintained. Read More

Int Orthop 2018 01 30;42(1):169-174. Epub 2017 Sep 30.

Bone and Joint Reconstruction Research Center, Shafa Orthopedic Hospital, Iran University of Medical Sciences, Tehran, Iran.

Purpose: Several therapeutic strategies have been used for managing unicameral bone cyst (UBC) of the proximal femur. However, there is insufficient evidence to support one treatment over another, and the optimal treatment is controversial. This study aims at describing our experience with surgical reconstruction of paediatric UBCs of the proximal femur using a proximal locking plate and fibular strut allograft. Read More

Injury 2017 Aug;48 Suppl 2:S44-S49

Orthopedics Smt. Kashibai Navale Medical College and General Hospital, Pune, Maharashtra, India.

Objectives: The aim of this study was to assess fracture union and complications following use of dynamic hip screw (DHS) with internal bone grafting in treatment of unstable delayed presented intracapsular neck femur fractures in patients younger than 65 years of age.

Material And Methods: Thirty two patients with displaced intracapsular neck femur fractures(Garden III and IV, Pauwels III, with comminution) with delayed presentation (15-60 days) in the 45-65 year age group (mean 54.4±10. Read More

J Orthop Traumatol 2017 Dec 12;18(4):365-378. Epub 2017 Jul 12.

Orthopaedics and Traumatology Department, Benha Faculty of Medicine, Benha University, Farid Nada Street, Benha, Qualiobia, Egypt.

Background: Coxa vara is a radiological term describing a decrease in the neck-shaft angle to 120° or less. Coxa vara is associated with pathomechanical changes that can manifest clinically. If left untreated, coxa vara can affect the normal development of the pediatric hip. Read More

Int J Mol Sci 2017 Jun 11;18(6). Epub 2017 Jun 11.

Department of Emergency Medicine, Warren Alpert School of Medicine and Rhode Island Hospital, Providence, RI 02903, USA.

Deficiency of PRG4 (lubricin), the boundary lubricant in mammalian joints, contributes to increased joint friction accompanied by superficial and upper intermediate zone chondrocyte caspase-3 activation, as shown in lubricinnull (4) mice. Caspase-3 activity appears to be reversible upon the restitution of either endogenously in vivo, in a gene trap mouse, or as an applied lubricant in vitro. In this study we show that intra-articular injection of human PRG4 in vivo in 4 mice prevented caspase-3 activation in superficial zone chondrocytes and was associated with a modest decrease in whole joint friction measured ex vivo using a joint pendulum method. Read More

J Child Orthop 2017 ;11(1):64-70

Department of Paediatric Orthopaedics, The Royal Children's Hospital, Victoria, Australia.

Aims: The severe form of coxa vara, the 'shepherd's crook deformity', is always a consequence of a locally extensive form of polyostotic fibrous dysplasia (or McCune-Albright syndrome). Treatment of this deformity is a challenge. The soft bone does not tolerate any implant that depends on the stability of the cortical bone (like plates or external fixators). Read More

Am J Case Rep 2017 Apr 23;18:440-443. Epub 2017 Apr 23.

Department of Orthopaedics, Faculty of Medicine, University Clinical Center of Kosova, University of Prishtina, Prishtina, Kosovo.

BACKGROUND Coxa vara and pseudoarthrosis of the femoral neck after septic hip arthritis is a very rare disease. The aim of this study was to present a case with pseudoarthrosis of the femoral neck, with coxa vara after neonatal septic arthritis of the right hip, and treatment of the pseudarthrosis with proximal femoral valgus osteotomy. CASE REPORT A 12-month-old female, who had suffered neonatal septic arthritis with a five-day history of fever and painful right hip now demonstrated painless limping to the right hip, pelvic obliquity, Trendelenburg-Duchenne gait, limitation of hip abduction, lower-extremity length discrepancy with 3. Read More

J Clin Endocrinol Metab 2017 06;102(6):2019-2028

Department of Endocrinology and Diabetes, Birmingham Children's Hospital, Birmingham B4 6NH, United Kingdom.

Context: Recessive mutations in TMEM38B cause type XIV osteogenesis imperfecta (OI) by dysregulating intracellular calcium flux.

Objectives: Clinical and bone material phenotype description and osteoblast differentiation studies.

Design And Setting: Natural history study in pediatric research centers. Read More

Mol Imaging Radionucl Ther 2017 Feb;26(1):33-37

King Faisal Specialist Hospital and Research Center, Clinic of Pediatric Rheumatology, Riyadh, Saudi Arabia Phone: +996114427761 E-mail:

Objective: Camptodactyly-arthropathy-coxa-vara-pericarditis (CACP) syndrome is an autosomal recessive disorder caused by mutations in gene that encodes for proteoglycan 4, the main lubricant for joints and tendon surfaces. It is a non-inflammatory arthropathy, characterized by joint effusions and synovial hypertrophy. So far, there is no effective treatment for this disorder. Read More

J Arthroplasty 2017 07 14;32(7):2199-2203. Epub 2017 Feb 14.

Department of Orthopaedic Surgery, Seoul National University Bundang Hospital, Seongnam, South Korea.

Background: In total hip arthroplasty (THA) of hips with coxa vara, the femoral stems might be inserted in a varus alignment. To avoid varus insertion, we designed a technique, which we termed "trochantoplasty." In this procedure, the medial half of the greater trochanter was removed during THA. Read More

J Orthop Surg (Hong Kong) 2017 01;25(1):2309499017693532

2 Department of Orthopaedics, Lady Hardinge Medical College, Shaheed Bhagat Singh Marg, New Delhi, India.

Introduction: Defective mineralization of osteoid matrix prior to physeal closure causes rickets. Poor calcification of the cartilage matrix in the zone of provisional calcification causes flattened skull, rachitic rosary, bowed legs, coxa vara and brittle bones. The recent literature has seen an increase in the incidence of the disease in both developing and developed nations. Read More

Arch Orthop Trauma Surg 2017 Mar 2;137(3):431-439. Epub 2017 Feb 2.

Department of Orthopaedic Surgery, University of Ulm, Oberer Eselsberg 45, 89081, Ulm, Germany.

Introduction: The principle of implanting a calcar-guided short stem consists of an individual alignment alongside the medial calcar providing the ability of reconstructing varus and valgus anatomy in a great variety. However, still, there are broad concerns about the safety of extensive varus and valgus positioning in regard to stability, bony alterations, and periprosthetic fractures.

Materials And Methods: 216 total hip arthroplasties using a calcar-guided short stem (optimys, Mathys Ltd. Read More

J Pediatr Orthop B 2017 Jul;26(4):313-319

Children's Orthopaedic Center, Mumbai, Maharashtra, India.

The behavior and treatment of coxa vara and pseudarthrosis of the proximal femur secondary to sepsis is not well described. The aim of this study is to describe the pathoanatomy for coxa vara and pseudarthrosis in postseptic hips, evaluate progression of neck shaft angle (NSA), and discuss treatment. This is a retrospective case series of 20 patients (21 hips). Read More

J Pediatr Orthop 2017 Jan 30. Epub 2017 Jan 30.

Department of Orthopedics, Nemours/Alfred I. duPont Hospital for Children, Wilmington, DE.

Background: Coxa vara has been frequently reported in spondyloepiphyseal dysplasia congenita (SEDC), and proximal femoral osteotomy has been described as a useful treatment. The aim of this study was to discuss the clinical, radiographic, and gait outcomes after valgus extension osteotomy of the proximal femur. Changes of lumbar lordosis, associated with coxa vara correction, are reported as well as the outcome differences between different ages. Read More

Vet Comp Orthop Traumatol 2017 May 27;30(3):184-190. Epub 2017 Jan 27.

Samuel P. Franklin, MS, DVM, PhD, DACVS, DACVSMR, Department of Small Animal Medicine and Surgery, The College of Veterinary Medicine, University of Georgia, 501 D.W. Brooks Drive, Athens, GA 30602, United States, E-mail:

Objective: To determine whether femoral osteotomies that change frontal plane alignment without affecting torsion influence anteversion and inclination.

Methods: Femurs without deformity were scanned to create three-dimensional reconstructions. The femoral head-neck axis was identified by placement of a virtual intramedullary pin. Read More

J Orthop Surg (Hong Kong) 2016 12;24(3):387-391

Department of Orthopedics and Traumatology, Faculty of Medicine, Istanbul University, Istanbul, Turkey.

Purpose: To review the outcome of Wagner double intertrochanteric osteotomy for trochanteric overgrowth and a short femoral neck in 7 adolescents.

Methods: Records of one male and 6 females aged 15 to 20 years who underwent modified Wagner osteotomy for trochanteric overgrowth and a short femoral neck by a single senior surgeon were reviewed. The diagnoses were coxa vara (n=2), developmental dysplasia of the hip (n=3), Leg-Calve-Perthes (n=1), and proximal femoral focal deficiency (n=1). Read More

J Clin Orthop Trauma 2016 Oct-Dec;7(Suppl 1):8-11. Epub 2016 Nov 11.

Maulana Azad Medical College, Delhi, India.

Background: Non-union is one of the devastating complications of fracture neck of femur. Though a very rarely encountered entity in a toddler (1-3 years paediatric age group), non-united femoral neck fractures are reported in developing countries because of mismanagement by quacks and delay in referrals. For operative treatment, many different procedures have been described, including close/open reduction and internal fixation using K-wires, cannulated screws, fibula or nails. Read More

Knee Surg Sports Traumatol Arthrosc 2018 Sep 28;26(9):2580-2586. Epub 2016 Nov 28.

Department of Orthopedic, Zhongshan Hospital, Fudan University, No. 180, Rd. Fenglin, Shanghai, China.

Purpose: To investigate the orientations of the surgical epicondylar axis (SEA) of varus and non-varus knees in the coronal plane.

Methods: One-hundred and sixty-two knees from 81 Chinese patients undergoing total knee arthroplasty (TKA) were retrospectively investigated. The angle between the medial side of the femoral mechanical axis and the SEA (MA-SEA), as well as the physiological valgus angle, was measured in the coronal plane using three-dimensional reconstruction. Read More

J Ayurveda Integr Med 2016 Oct - Dec;7(4):249-254. Epub 2016 Nov 25.

S.S.S.B. Ayurvedic College and Hospital, Jaipur, 303603, Rajasthan, India.

Spondyloepiphyseal dysplasia tarda (SEDT) is a rare genetic disease in which patient suffers from short stature, short trunk and neck with disproportionately long arms, coxa vara, skeletal features such as barrel shaped chest, kyphosis, scoliosis and early arthropathy. Only limited medical and surgical management is available in modern medicine. A 15 years old male suffering from SEDT and diagnosed as Vata vyadhi was treated with Panchakarma therapy and selected Ayurvedic oral medicines. Read More

Am J Med Genet A 2017 Mar 26;173(3):733-739. Epub 2016 Nov 26.

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas.

Spondylometaphyseal dysplasia (SMD) corner fracture type (also known as SMD "Sutcliffe" type, MIM 184255) is a rare skeletal dysplasia that presents with mild to moderate short stature, developmental coxa vara, mild platyspondyly, corner fracture-like lesions, and metaphyseal abnormalities with sparing of the epiphyses. The molecular basis for this disorder has yet to be clarified. We describe two patients with SMD corner fracture type and heterozygous pathogenic variants in COL2A1. Read More

Hip Int 2016 Nov 15;26(6):554-560. Epub 2016 Oct 15.

 Department of Orthopaedics, Center Orthopédique Santy, Lyon - France.

Background: Varus inclination of the uncemented stem is not necessarily a technical error. The proximal femoral anatomy of hips with a coxa vara deformity frequently predisposes varus inclination.

Methods: We reviewed a series of 200 patients undergoing primary uncemented THA with the Corail® hip system. Read More

Hip Int 2016 Nov 23;26(6):608-611. Epub 2016 May 23.

Department of Orthopaedic Surgery, Siriraj Hospital, Mahidol University, Bangkok - Thailand.

Objectives: Fractures of the proximal femur account for less than 1% of all children's fractures. Because of this, most orthopaedic surgeons lack enough experience in treating them. This adds to the rather high incidence of complications especially nonunion. Read More

Indian Heart J 2016 Sep 15;68 Suppl 2:S284-S287. Epub 2016 Apr 15.

Professor and Head, CDFD - Centre for DNA Fingerprinting and Diagnostics, Nampally, Hyderabad, India.

Familial constrictive pericarditis is extremely rare. We report a case of two brothers both suffering constrictive pericarditis along with having multiple painless joint deformities. Genetic workup confirmed the clinical diagnosis of camptodactyly-arthropathy-coxa vara-pericarditis (CACP) syndrome CACP syndrome and also revealed a rare mutation in the causative gene. Read More

J Pediatr Orthop B 2017 Jul;26(4):320-328

Department of Orthopaedic Surgery, Kasr Al-Ainy School of Medicine, Faculty of Medicine, Cairo University, Cairo, Egypt.

Developmental coxa vara (DCV) develops during early childhood between the age of independent walking and 6 years. The deformity includes a decrease in the neck-shaft angle and femoral retroversion. Recently, good results have been reported using external fixator systems for the correction of proximal femoral deformities secondary to slipped capital femoral epiphysis, Perthes' disease in children, and percutaneous proximal femoral osteotomy for coxa vara. Read More

Indian J Med Res 2016 Jun;143(6):834-835

Department of Orthopaedics & Traumatology, Osmania General Hospital, Afzalgunj, Hyderabad 500 012, Telangana, India.

Clin Orthop Surg 2016 Sep 10;8(3):310-5. Epub 2016 Aug 10.

Faculty of Medicine, Zagazig University Hospitals, Sharkia, Egypt.

Background: Although the valgus subtrochanteric osteotomy is considered as a standard surgical treatment for coxa vara, there is no consensus on the optimal method of fixation and osteotomy technique. Fixation of the osteotomy has been achieved by various methods including external fixation and internal fixation with pins and cerclage and a variety of plates. The aim of this study is the evaluation of the results of developmental coxa treated by Y intertrochanteric valgus osteotomy fixed with a T-buttress plate compared with other methods of fixation in the literature. Read More