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Clin Orthop Surg 2020 Jun 14;12(2):258-262. Epub 2020 May 14.

Department of Orthopedic Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.

The mainstream surgery for valgus-impacted femoral neck fractures (FNFs) is closed reduction and internal fixation under fluoroscopy. However, femoral neck shortening and anterior femoroacetabular impingement are common complications in healed valgus-impacted FNFs after fixation. Some methods have been reported to prevent complications, but these techniques require the use of a transfixing guide wire that passes through the femoral head, which may cause articular cartilage damage. Read More

Arch Orthop Trauma Surg 2020 May 30. Epub 2020 May 30.

Gelenkzentrum Bergisch Land, Freiheitstraße 203, 42853, Remscheid, Germany.

Introduction: Inaccurate stem implantation can cause unsatisfactory offset reconstruction and may result in insufficient gluteal muscle function or aseptic loosening. In this study, stem alignment of a collarless straight tapered HA-coated stem was retrospectively analyzed during the learning phase of the direct anterior approach (DAA) for primary total hip arthroplasty (THA).

Material And Methods: From Jan 2013 to Jun 2015, a total of 93 cementless THA were implanted in patients with unilateral coxarthrosis via the DAA in a two surgeon setting using the Corail or Trendhip stem (DePuy Synthes or Aesculap). Read More

J Orthop 2020 Nov-Dec;22:207-212. Epub 2020 May 6.

Department of Orthopaedics, Kasturba Hospital, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, India.

Objectives: Pediatric femoral neck fractures were reviewed to compare complications with the time of presentation.

Methods: 34 pediatric femoral neck fractures were studied to detect union time, avascular necrosis, premature physis fusion, and the neck-shaft angle. All complications were comparable between both groups. Read More

Pediatr Radiol 2020 Jul 2;50(8):1115-1122. Epub 2020 May 2.

Child and Adolescent Protection Center, Children's National Hospital, Washington, DC, USA.

Background: Proximal femoral physeal fractures are rare in abused children. Recognition may be hampered due to their rarity and lack of an ossified femoral head. Prompt diagnosis and treatment are essential to preventing coxa vara. Read More

Cureus 2020 Mar 23;12(3):e7371. Epub 2020 Mar 23.

Pediatrics, Civil Hospital Karachi, Dow University of Health Sciences, Karachi, PAK.

Metaphyseal chondrodysplasia, Schmid type (MDSC) is a rare inherited autosomal disorder with characteristic skeletal deformities striking on radiological imaging, which includes metaphyseal cupping and fraying. Physical examination reveals short stature in early childhood, frontoparietal bossing, rachitic rosary, genu varum and valgum, and coxa vara usually. We believe that the constellation of clinical and radiographic findings of MDSC might look similar to vitamin D resistant rickets; hence, genetic analysis is needed to overcome diagnostic challenges faced by physicians to avoid unnecessary vitamin D supplementation in individuals. Read More

Indian J Orthop 2020 Feb 31;54(1):83-86. Epub 2020 Jan 31.

Department of Orthopaedics, Ganga Hospital, 313, Mettupalayam road, Coimbatore, 641043 Tamil Nadu India.

Bilateral Femoral neck stress fractures (FNSFs) are rare without any underlying metabolic disease or repeated strenuous activities like athletes or military recruits. It constitutes about 5-8% of all stress fractures. Treatment options are still controversial. Read More

Rev Prat 2019 Dec;69(10):1124-1128

Service de chirurgie orthopédique et traumatologique, hôpital Henri-Mondor, Créteil, France.

FEMORAL NECK FRACTURE. Femoral neck fractures represent the third most common type of fracture in traumatology. The diagnosis is based on the clinic and radiographs of the pelvis and the hip. Read More

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2020 Mar;34(3):404-408

Department of Othopedics, West China Hospital, Sichuan University, Chengdu Sichuan, 610041, P.R.China.

Objective: To review the progress of hip fracture treatment in children.

Methods: Literature about the hip fracture treatment in children was extensively reviewed and summarized in terms of anatomy and blood supply, fracture classification, surgical treatment principles, and complications.

Results: The anatomical structure of children's hips and the characteristics of peripheral blood supply constantly change with age. Read More

Orthop Surg 2020 Apr 11;12(2):639-644. Epub 2020 Mar 11.

Department of Orthopedics, Xi'an Hong Hui Hospital, Xi'an Jiaotong University Health Science Center, Xi'an, China.

Objective: To comprehensively assess the differences in outcome between open reduction and closed reduction for children and adolescents with femoral neck fractures.

Methods: Based on the predetermined strategies, eligible studies were obtained by searching Embase, the Cochrane Library, and PubMed databases (retrieval time: June 2018) and through manual retrieval for paper documents. The 95% confidence intervals (CI) and risk ratios (RR) were used as evaluation indexes. Read More

J Orthop Surg Res 2020 Feb 19;15(1):58. Epub 2020 Feb 19.

Department of Pediatric Orthopedics, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 1665 Kongjiang Road, Yangpu District, Shanghai, 200092, China.

Background: Pediatric femoral neck fracture is a rare injury but yields frequent complications. However, there is a paucity of data regarding the risk factors for these complications.

Purpose: The present article reports the rate of complications after femoral neck fracture in pediatric patients and investigates the possible risk factors. Read More

Instr Course Lect 2019 ;68:443-452

Proximal femoral fractures in the skeletally immature patient can be challenging for the orthopaedic surgeon to manage. This type of injury includes the femoral head/neck, intertrochanteric, and subtrochanteric fractures. The Delbet classification system historically describes all injuries in the pediatric proximal femur, except subtrochanteric fractures. Read More

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2020 Jan;34(1):32-36

Department of Orthopedics, the People's Hospital of Guangxi Zhuang Autonomous Region, Nanning Guangxi, 530021,

Objective: To compare the effectiveness of proximal femoral nail anti-rotation (PFNA) in the treatment of intertrochanteric fracture of femur in traction bed supine position and non-traction bed lateral position.

Methods: A retrospective analysis of 102 elderly patients with intertrochanteric fracture of femur who met the selection criteria between January 2013 and April 2018 was made. According to the different operative positions, the patients were divided into two groups: group A (50 cases, PFNA internal fixation in traction bed supine position) and group B (52 cases, PFNA internal fixation in non-traction bed lateral position). Read More

Pak J Med Sci 2020 Jan;36(1):S94-S97

Mansoor Ali Khan, FCPS. Department of Orthopedics, The Indus Hospital, Karachi, Pakistan.

Slipped capital femoral epiphysis (SCFE) in children after treatment of femoral neck fracture is a very rare condition. This complication should be recognized promptly and treated urgently. The risk of development of this complication can be minimized by anatomical reduction of the fracture and stable internal fixation of the fracture. Read More

Medicine (Baltimore) 2020 Jan;99(1):e18613

Children's Orthopedic Center, Children's Hospital Los Angeles.

Postoperative fever in pediatric patients following reconstructive hip surgery is of unknown significance. This study identifies the prevalence of postoperative fever after corrective hip surgery, its relationship to infection, and whether preventative use of anti-pyretics affects patient outcomes.Overall, 222 patients who underwent a varus derotational osteotomy (VDRO) between 11/1/2004 to 8/1/2014 with minimum 6 months follow up were retrospectively identified. Read More

BMC Med Genet 2019 12 19;20(1):200. Epub 2019 Dec 19.

Department of Orthopedic Surgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, 600 Yi-Shan Rd., Shanghai, 200233, People's Republic of China.

Background: Schmid-type metaphyseal chondrodysplasia (MCDS) is an autosomal dominant disorder caused by COL10A1 mutations, which is characterized by short stature, waddling gait, coxa vara and bowing of the long bones. However, descriptions of the expressivity of MCDS are rare.

Methods: Two probands and available family members affected with MCDS were subjected to clinical and radiological examination. Read More

J Surg Res 2020 Apr 13;248:14-19. Epub 2019 Dec 13.

Department of Orthopedics, Fuzhou Second Hospital affiliated to Xiamen University, Fuzhou, China. Electronic address:

Background: This retrospective multicenter study investigated whether the presence of free fracture fragments is associated with the clinical outcome of adolescents with Delbet II femoral neck fracture (FNF).

Materials And Methods: The study population comprised 74 adolescents with Delbet II FNF, with an average age of 13.31 y (range, 10-17 y). Read More

J Pediatr Orthop B 2020 Jan;29(1):22-28

Tuckahoe Orthopaedic Associates, Richmond, Virginia, USA.

The objective of this study is to present the clinical and radiographic data collected from patients who were treated with a varus derotational osteotomy using Rush rod fixation and compare this to published norms of outcomes using blade plate fixation. A retrospective chart and radiograph review was conducted after identifying 44 patients with 61 hips who underwent varus derotational osteotomy with Rush rod fixation at our institution between 2006 and 2016. We identified 44 patients with 61 hips who underwent the procedure. Read More

JBJS Case Connect 2019 Dec;9(4):e0383

Department of Orthopedic Surgery, Far Eastern Memorial Hospital, New Taipei City, Taiwan.

Case: We reported a case of a 25-year-old woman with idiopathic bilateral coxa vara who had initial presentation of hip osteoarthritis. She was later treated with bilateral subtrochanteric valgus osteotomy. A good functional outcome was recorded without nonunion or deformity recurrence. Read More

Orthop Traumatol Surg Res 2019 12 28;105(8S):S267-S274. Epub 2019 Oct 28.

Centre de chirurgie de la hanche, clinique du sport, Medipôle Garonne, 31036 Toulouse, France.

Coxa profunda is a complex entity that can result in femoro-acetabular impingement (FAI). A meticulous evaluation of the type of acetabular overcoverage is essential to determine which treatment is best suited to each individual patient. Focal overcoverage with no posterior impingement can be treated by arthroscopic recontouring of the disproportionate acetabular wall. Read More

Orthop Surg 2019 Oct;11(5):826-834

Department of Orthopaedics, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.

Objective: To assess the treatment of osteosarcomas of the femoral diaphysis through wide en bloc excision and reconstruction of the defect by pasteurized autograft combined with vascularized fibular transfer.

Methods: A single-center, retrospective study was performed of 15 selected patients (six females, nine males) whose lesion in the middle diaphysis of the femur were treated by en bloc excision and reconstruction of the bone defect with recycled pasteurized autograft combined with vascularized fibular graft between January 2000 and December 2011. The primary diagnoses of the patients were osteosarcoma (15 patients), and one of these patients had a pathological fracture. Read More

Z Orthop Unfall 2019 Oct 21. Epub 2019 Oct 21.

Clinic and Polyclinic for Orthopedics and Trauma Surgery, University Hospital Bonn.

Purpose: Hip screening sonography according to Graf in rare cases yields the appearance of a double femoral head, aptly named the Double-Head-Sign. The goal of this retrospective study is to offer a definition of this rare sign, evaluate its incidence of occurrence and compare the sonographic findings with the clinical findings.

Materials And Methods: This Double-Head-Sign is caused by the overlap of the trochanter major with the actual head of the femur in cases of coxa vara. Read More

J Am Acad Orthop Surg 2020 Jan;28(1):10-19

From the Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC.

Pediatric proximal femur fractures are high-energy injuries with predictable and morbid complications. Osteonecrosis of the femoral head is the most common complication with identified risk factors including fracture type, patient's age, degree of displacement, timing to reduction, and stability of fixation. Additional complications include nonunion, coxa vara, and premature physeal arrest. Read More

Clin Rheumatol 2020 Feb 18;39(2):553-560. Epub 2019 Oct 18.

Institute of Medical Chemistry, Medical University of Vienna, Vienna, Austria.

Background: Axial and extra-axial deceleration in function and progressive joint pain with subsequent development of antalgic gait associated with swellings, and stiffness of the joints with loss of the physiological spine biomechanics were the natural history in this group of patients. Clinical and radiological phenotypes have been analysed carefully to further understand the aetiology behind.

Methods: Seven patients (three children around the age of 9-11 and one child of 17 years old). Read More

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2019 Oct;33(10):1250-1253

Department of Trauma Emergency Center, Key Laboratory of Orthopaedics, the Third Hospital of Hebei Medical University, Shijiazhuang Hebei, 050051,

Objective: To evaluate the effectiveness of the leverage reduction with proximal femoral nail antirotation (PFNA) ball head screw driver for difficult-reducing intertrochanteric fracture.

Methods: The clinical data of 8 patients with difficult-reducing intertrochanteric fractures between July 2015 and February 2018 were retrospectively analysed. There were 3 males and 5 females, aged 66-89 years, with an average age of 76. Read More

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2019 Oct;33(10):1216-1222

Department of Orthopedic Surgery, Yangpu Hospital, Tongji University, Shanghai, 200090,

Objective: To introduce the reduction concept of anteromedial cortical support in the treatment of intertrochanteric fracture, summarize the history, characteristics, biomechanics, and clinical applications, discuss the unsolved problems and prospect the future directions.

Methods: Relevant domestic and foreign studies on cortical support reduction of intertrochanteric fracture in recent years were reviewed. Conclusions were drawn combined with clinical experience. Read More

J Child Orthop 2019 Aug;13(4):361-370

Beijing Research Institute of Traumatology and Orthopaedics, Beijing, China.

Purpose: To evaluate the risk factors for developmental coxa vara (DCV) recurrence following valgus osteotomy of the proximal femur.

Methods: We retrospectively reviewed records of 32 DCV patients (46 hips) treated surgically (2005 to 2012). Recurrence-related factors, including age at initial surgery, side, sex, fixation methods, diagnosis of coxa vara, premature capital femoral physeal closure and postoperative Hilgenreiner epiphyseal (HE) angle, head-shaft (HS) angle, medial femoral offset and posterior slope angle (PSA) were analyzed. Read More

JBJS Case Connect 2019 Jul-Sep;9(3):e0321

Faculty of Medicine, University of Bern, Bern, Switzerland.

Case: A 10-year-old girl presented after possible occult hip trauma, with shortening of the leg being the initial clinical symptom, followed by motion-dependent pain. She had limited external rotation in extension with anterior apprehension. Radiographically, the deformity was an anterior tilt of the epiphysis with coxa vara. Read More

J Orthop Trauma 2019 Aug;33 Suppl 8:S22-S26

Division of Pediatric Orthopaedic Surgery, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH.

Pediatric hip fractures are uncommon injuries but are associated with a high complication rate including avascular necrosis, coxa vara, nonunion, and premature physeal arrest. This is due in part to the unique anatomy of the proximal femur. Management principles are aimed at minimizing the risk of complications and emphasize the importance of early treatment with anatomic reduction and stable internal fixation with a low threshold for supplementing fixation with a spica cast. Read More

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2019 Jun;33(6):666-670

Department of Orthopedics, Shanghai Zhongye Hospital, Shanghai, 200941,

Objective: To explore the effectiveness of proximal femoral nail antirotation (PFNA) assisted by mesh locator in treatment of intertrochanteric fracture in the elderly.

Methods: Ninety-four elderly patients with intertrochanteric fractures admitted between August 2014 and July 2017 were selected as the study subjects. They were randomly divided into trial group (48 cases) and control group (46 cases). Read More

Mol Syndromol 2019 May 9;10(3):167-170. Epub 2019 Feb 9.

Unit of Medical Genetics, Department of Pediatrics, Faculty of Medicine, University of Los Andes, Mérida, Venezuela.

Schmid-type metaphyseal chondrodysplasia (MIM 156500) is an uncommon autosomal dominant skeletal dysplasia caused by heterozygous mutations in the gene (MIM 120110) encoding the α1(X) chains of type X collagen. We report an 8-year-old girl with waddling gait, short stature, mild dorsal scoliosis, coxa vara, short lower limbs, bowing of the femurs, genu varum, and metaphyseal fraying and splaying, who is a carrier of a novel heterozygous 2-bp (c.1894_1895dupTA; p. Read More

J Pediatr Orthop 2019 Jul;39(6):282-288

Department of Orthopedics, Nemours/Alfred I. duPont Hospital for Children, Wilmington, DE.

Background: Coxa vara has been frequently reported in spondyloepiphyseal dysplasia congenita (SEDC), and proximal femoral osteotomy has been described as a useful treatment. The aim of this study was to discuss the clinical, radiographic, and gait outcomes after valgus extension osteotomy of the proximal femur. Changes of lumbar lordosis, associated with coxa vara correction, are reported as well as the outcome differences between different ages. Read More

J Orthop Surg Res 2019 May 30;14(1):165. Epub 2019 May 30.

Department of Orthopaedics and Orthopaedic Surgery, Saarland University, Homburg, Germany.

Introduction: Stem malalignment can affect offset reconstruction and may result in gluteal muscle insufficiency. In this retrospective study, a novel geometric angle named 'critical trochanter angle' (CTA) is described and investigated towards the risk of malposition of a collarless straight tapered hydroxyapatite-coated stem in primary total hip arthroplasty (THA).

Material And Methods: A total of 100 cementless THA were implanted in patients with unilateral coxarthrosis via the direct anterior (n = 50) or direct lateral Hardinge approach (n = 50) in a two surgeon setting using the Corail® or Trendhip® stem (DePuy Synthes or Aesculap). Read More

J Clin Orthop Trauma 2019 May-Jun;10(3):593-598. Epub 2018 Jun 28.

Department of Orthopaedic Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Background: Coxa vara is a hip deformity in which the femoral neck-shaft angle decreases below its normal value. Standard surgical treatment for this condition is corrective valgus osteotomy. Appropriate correction of the Hilgenreiner-epiphyseal angle is important to prevent recurrence. Read More

Medicine (Baltimore) 2019 Apr;98(16):e15294

University Children's Hospital Basel (UKBB), Department of Pediatric Surgery, 4056 Basel.

Rationale: Damage control is a staged surgical approach to manage polytraumatized patients. The damage control approach comprises three steps. First, bleeding is controlled and fractures are stabilized temporarily; second, vital parameters are stabilized and the child is rewarmed in the intensive care unit; and third, the child is reoperated for definitive repair of injuries. Read More

Orthopade 2019 Aug;48(8):685-692

Orthopädische Klinik, Olgahospital, Klinikum Stuttgart, Kriegsbergstr. 62, 70174, Stuttgart, Deutschland.

In slipped capital femoral epiphysis (SCFE) atypical causes can be found in about 5% of cases. The patients' age differs from the typical age of SCFE patients of between age 10 and 16. There are numerous causes of atypical SCFE: different endocrine disorders, sequelae of chronic renal failure and effects of radiation and chemotherapy on the proximal femoral physis. Read More

Am J Hum Genet 2019 03 14;104(3):422-438. Epub 2019 Feb 14.

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Texas Children's Hospital, Houston, TX 77030, USA. Electronic address:

SPONASTRIME dysplasia is an autosomal-recessive spondyloepimetaphyseal dysplasia characterized by spine (spondylar) abnormalities, midface hypoplasia with a depressed nasal bridge, metaphyseal striations, and disproportionate short stature. Scoliosis, coxa vara, childhood cataracts, short dental roots, and hypogammaglobulinemia have also been reported in this disorder. Although an autosomal-recessive inheritance pattern has been hypothesized, pathogenic variants in a specific gene have not been discovered in individuals with SPONASTRIME dysplasia. Read More

Joint Bone Spine 2019 07 31;86(4):511. Epub 2019 Jan 31.

Rheumatology Department, Centro Hospitalar e Universitario de Coimbra EPE, Coimbra, Portugal.

Medicine (Baltimore) 2019 Jan;98(1):e13780

Department of Medical Chemistry, Medical University of Vienna, Vienna, Austria.

Spondyloepiphyseal dysplasia congenita (SEDC) is an autosomal dominant disorder, characterized by disproportionate dwarfism with short spine, short neck associated with variable degrees of coxa vara. Cervical cord compression is the most hazardous skeletal deformity in patients with SEDC which requires special attention and management.Ten patients with the clinical and the radiographic phenotypes of spondyloepiphyseal dysplasia congenita have been recognized and the genotype was compatible with single base substitutions, deletions or duplication of part of the COL2A1 gene (6 patients out of ten have been sequenced). Read More

Bone 2019 04 30;121:163-171. Epub 2018 Dec 30.

CHU Sainte Justine Research Centre and Department of Pediatrics, University of Montreal, Montreal, QC H3T 1C5, Canada. Electronic address:

Heterozygous pathogenic variants in the FN1 gene, encoding fibronectin (FN), have recently been shown to be associated with a skeletal disorder in some individuals affected by spondylometaphyseal dysplasia with "corner fractures" (SMD-CF). The most striking feature characterizing SMD-CF is irregularly shaped metaphyses giving the appearance of "corner fractures". An array of secondary features, including developmental coxa vara, ovoid vertebral bodies and severe scoliosis, may also be present. Read More

J Orthop Case Rep 2018 May-Jun;8(3):33-37

Department of Orthopaedics, Sri Ramachandra Medical University, Chennai, Tamil Nadu, India.

Introduction: Fibrous dysplasia is a rare benign disorder of the skeletal system characterized by fibro-osseous proliferation with intervening areas of normal or immature bone in the intramedullary region. It can either be a monostotic (involves one bone) or a polyostotic (involves more than one bone) presentation and usually occurs equally in males and females. Deformities such as scoliosis and shepherd's crook deformity are frequently encountered in the polyostotic form. Read More

Knee Surg Sports Traumatol Arthrosc 2019 Sep 11;27(9):3041-3047. Epub 2018 Dec 11.

1st Orthopaedic and Traumatologic Clinic, IRCCS Istituto Ortopedico Rizzoli, Via Giulio Cesare Pupilli 1, 40136, Bologna, Italy.

Purpose: The aim of this study was to assess whether preoperative valgus or varus deformity affected survivorship after total knee arthroplasty (TKA) and to quantify the risk factors for implant failure in a registry-based population.

Methods: The Emilia-Romagna Registry of Prosthetic Orthopedic Implants was examined regarding TKAs performed on patients with a preoperative diagnosis of valgus or varus deformity. Demographics, implant characteristic and survivorships were investigated and compared. Read More

Indian J Orthop 2018 Sep-Oct;52(5):501-506

Department of Orthopaedics, Christian Medical College, Vellore, Tamil Nadu, India.

Paediatric femoral neck fractures are uncommon injuries and are usually caused by high-energy trauma. Low-energy trauma can result in pathologic neck fractures and stress fractures of the neck, due to repetitive activity. Surgical options can vary based on age, Delbet classification and displacement of the fracture. Read More

Indian J Pediatr 2019 Feb 12;86(2):183-185. Epub 2018 Sep 12.

Department of Radiology, SMS Medical College and Associated Hospital, Jaipur, Rajasthan, India.

Schmid type metaphyseal chondrodysplasia (SMCD) is a rare skeletal dysplasia, characterized by short stature, short limbs, bowing of the legs, and radiographic features of metaphyseal irregularities with fraying and splaying, more severe at the knee. It is caused by mutations of the COL10A1 gene. The authors present an Indian patient with a novel COL10A1 gene mutation. Read More

J Knee Surg 2019 Aug 7;32(8):820-824. Epub 2018 Sep 7.

Department of Trauma and Hand Surgery, Universitätsklinikum Düsseldorf, Düsseldorf, Germany.

Total knee arthroplasty (TKA) is a very successful procedure. The alignment in TKA has been identified as being of importance to prevent early implant failure and patient dissatisfaction. Our hypothesis was that patients with a preoperative varus deformation remaining in a slight varus alignment as their natural alignment after TKA will have superior clinical results compared with patients who are restored in neutral alignment. Read More

Oper Orthop Traumatol 2018 Oct 8;30(5):379-386. Epub 2018 Aug 8.

Klinik und Poliklinik für Orthopädie und Unfallchirurgie, Universitätsklinikum Bonn, Sigmund-Freud-Str. 25, 53105, Bonn, Deutschland.

Objective: Growth disorders (e. g. caused by congenital hip dislocation, Perthes disease or bacterial coxitis) often lead to an infantile deformity of the proximal femur with a shortened femoral neck and displaced grater trochanter. Read More

Am J Med Genet A 2018 09 31;176(9):2009-2016. Epub 2018 Jul 31.

Division of Pediatric Genetics, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey.

Our understanding of the molecular basis of the genetic disorders of the skeleton has steadily increased, as the application of high-throughput sequencing technology has expanded. One of the newcomers is Spondyloepimetaphyseal dysplasia Faden-Alkuraya type. In this study, we aimed to further delineate the clinical, radiographic, and molecular findings of this entity in five affected individuals from two unrelated families. Read More

Orthop Surg 2018 Aug 19;10(3):241-246. Epub 2018 Jul 19.

Institute of Medical Chemistry, Medical University of Vienna, Austria.

Objectives: There are several types of metaphyseal chondrodysplasia and various clinical types have been differentiated. The Schmid type of metaphyseal chondrodysplasia is the most common. Diffuse metaphyseal flaring, irregularity, and growth plate widening, which are most severe in the knees, are the most striking radiological features of this disease. Read More

Knee 2018 Oct 17;25(5):825-833. Epub 2018 Jul 17.

Funktionsbereich Bewegungsanalytik, IEMM, Universitätsklinikum Münster, Albert-Schweitzer Campus 1, Gebäude D3, 48129 Münster, Germany.

Background: Knee osteoarthritis (KOA) is the most common form of arthritis with an estimated lifetime prevalence of 45%. The use of orthotic devices is a generally accepted conservative therapy in KOA. A new conservative treatment is an ankle-foot orthosis (AFO); however, studies on the biomechanical effects are limited. Read More