5,898 results match your criteria Condyloma Acuminatum

Oral condyloma acuminatum with changes in excretory duct of minor salivary gland: An unusual case report and review of literature.

J Oral Maxillofac Pathol 2020 Sep-Dec;24(3):588. Epub 2021 Jan 9.

Department of General Surgery, Care Multispecialty Hospital, Vadodara, Gujarat, India.

Condyloma acuminatum (CA) is human papilloma virus-induced disease, rarely involving oral cavity, usually sexually transmitted and frequently occurs in anogenital areas. Oral lesions are being present predominantly on the tongue, lip mucosa, buccal mucosa, palate and floor of the mouth. The disease is more common in teenagers and appears as solitary or multiple, sessile or pedunculated masses. Read More

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January 2021

HPV infection upregulates the expression of ZNT-1 in condyloma acuminatum.

Eur J Histochem 2021 Apr 28;65(2). Epub 2021 Apr 28.

Hubei Cancer Clinical Study Centre and Hubei Key Laboratory of Tumor Biological Behaviors, Zhongnan Hospital, Wuhan University, Wuhan.

Condyloma acuminata (CA) are benign anogenital warts caused by human papillomavirus (HPV) infection with a high recurrence rate. Despite its high contagiousness, high recurrence rate and potential for malignant transformation, effective treatments for CA have not yet been developed. Accordingly, it is necessary to clarify the mechanisms underlying CA development. Read More

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Dysregulation of autophagy-associated microRNAs in condyloma acuminatum.

Infect Genet Evol 2021 Apr 24:104878. Epub 2021 Apr 24.

Department of Dermatology, The First Affiliated Hospital of Jinan University, Jinan University, Guangzhou 510630, China; Dermatology Institute of Jinan University, Jinan University, Guangzhou 510630, China. Electronic address:

Condyloma acuminatum, which is caused by low-risk human papillomavirus (lrHPV) infection, is one of the most common sexually transmitted diseases. Autophagy is thought to be associated with condyloma acuminatum, but how the autophagy process is regulated remains unclear. MicroRNAs (miRNAs) are important regulators of gene transcription that play a central role in many biological processes, including autophagy and viral infection. Read More

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Perianal amebiasis cutis masked by giant condyloma acuminatum in a HIV-seropositive patient.

J Dermatol 2021 Apr 22. Epub 2021 Apr 22.

Department of Dermatology, Kyorin University Faculty of Medicine, Tokyo, Japan.

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Efficacy and Safety of Giant Condyloma Acuminatum with Monotherapy of Topical Traditional Chinese Medicine: Report of Eight Cases.

Infect Drug Resist 2021 9;14:1375-1379. Epub 2021 Apr 9.

Department of Dermatology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, People's Republic of China.

Background: Giant condyloma acuminatum (GCA), also called Buschke-Löwenstein tumor, presents as a verrucous infiltrating lesion and is caused by sexual transmission of human papilloma virus. The optimal treatment is controversial and there are no standard guidelines because of its rarity and frequent recurrence. It has a relatively high local recurrence rate. Read More

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[HPV vaccination and the prevention of genital warts and precancerous lesions-current evidence and evaluation].

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 2021 May 13;64(5):590-599. Epub 2021 Apr 13.

Lehrstuhl für Epidemiologie, Fakultät für Sport- und Gesundheitswissenschaften, Technische Universität München, Georg-Brauchle-Ring 56, 80992, München, Deutschland.

Human papillomaviruses (HPVs) can cause both benign and malignant tumors. To date, more than 200 HPV types have been discovered, of which 12 are currently classified as high risk for cervical cancer. HPV types that affect the anogenital tract are sexually transmitted. Read More

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Unusual Clinical Presentation of Giant Extragenital Condyloma.

Acta Dermatovenerol Croat 2020 Dec;28(7):240-241

Andrija Jovic, MD, Clinical Center of Nis, Clinic of Dermatovenereology , Bulevar Zorana Djindjica 48, Nis, Serbia;

Dear editor, Condylomata accuminatum (CA) is a human papillomavirus (HPV) related sexually transmitted infection (STI), clinically characterized by solitary or even clustered dark red or pink lesions solely affecting the anogenital area (1). CA involving the extragenital, non-mucosal skin has been sporadically reported (2-4). Diagnosis of CA is usually straightforward when the lesions are located on the anogenital area. Read More

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December 2020

Response of pruritic scrotal epidermolytic acanthomas to pimecrolimus 1% cream.

Dermatol Online J 2021 Feb 15;27(2). Epub 2021 Feb 15.

Department of Dermatology, Consorci Hospital General Universitari de Valencia, Avenida Tres Cruces 2.

Epidermolytic acanthomas (EA) are rare benign tumors of unclear etiology that present as flat, sometimes slightly keratotic, pale or whitish papules that are usually asymptomatic. Not uncommonly, their clinical appearance in the anogenital area might lead to misdiagnosis as other lesions that commonly develop at this site, such as condylomata acuminata. Though mainly asymptomatic, there are also reports of EA presenting with persistent genital pruritus. Read More

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February 2021

Changing trends of sexually transmitted infections and estimation of partner notification at a tertiary care center in North India.

Indian J Sex Transm Dis AIDS 2020 Jul-Dec;41(2):176-180. Epub 2020 Jul 31.

Department of Dermatology Venereology and Leprology, Government Medical College, Patiala, Punjab, India.

Background: Sexually transmitted infections (STIs) are dynamic and show a variable prevalence in different parts of the country. Moreover, the prevalence changes with time in the same geographical area. It is important to have the knowledge of current trend of STIs and partner notification (PN) rate in a particular area for the effective implementation of preventive and control measures. Read More

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A case of anal condyloma acuminatum observed by endocytoscopy.

VideoGIE 2021 Mar 9;6(3):141-143. Epub 2021 Jan 9.

Department of Pathology, Shinko Hospital, Kobe, Japan.

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Cronkhite-Canada syndrome associated with perianal condyloma acuminatum with malignant transformation: A case report.

Medicine (Baltimore) 2021 Mar;100(10):e25067

Binzhou Medical University Hospital, The Yellow Rive Second Road, Binzhou City, Shandong Province, China.

Rationale: Cronkhite-Canada syndrome (CCS) is a rare non-familial polyposis syndrome characterized by multiple gastrointestinal polyps with the ectodermal triad. To date, many complications of CCS have been reported in the literature, but perianal condyloma acuminatum with malignant transformation has not been included.

Patient Concerns: This report presents the case of a 52-year-old Chinese man who presented with diarrhea, loss of appetite, and weight loss. Read More

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Topical microbicides for preventing sexually transmitted infections.

Cochrane Database Syst Rev 2021 03 13;3:CD007961. Epub 2021 Mar 13.

Cochrane South Africa, South African Medical Research Council, Cape Town, South Africa.

Background: This is a updated version of our Cochrane Review published in Issue 6, 2012. Sexually-transmitted infections (STIs) continue to rise worldwide, imposing an enormous morbidity and mortality burden. Effective prevention strategies, including microbicides, are needed to achieve the goals of the World Heath Organization (WHO) global strategy for the prevention and control of these infections. Read More

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A case of giant condyloma acuminatum (Buschke-Lowenstein tumor) successfully treated with acitretin.

Dermatol Ther 2021 Feb 22:e14905. Epub 2021 Feb 22.

The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.

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February 2021

Vitiligo-Like Depigmentation following Treatment with Imiquimod 5% Cream for Condylomata Acuminata.

Case Rep Dermatol 2021 Jan-Apr;13(1):36-41. Epub 2021 Jan 25.

Department of Dermatology, Derma Clinics, Riyadh, Saudi Arabia.

Imiquimod cream is an immunomodulatory agent that has been approved by the US Food and Drug Administration for use in the treatment of anogenital warts (condylomata acuminata) due to its local immune effects in activating Toll-like receptors 7 and 8 on antigen-presenting cells, resulting in reduction of the viral load of human papillomavirus with subsequent wart regression. After its application, some side effects are commonly reported, including erythema, edema, scaling, erosion, and ulceration. While pigmentary changes, including vitiligo-like depigmentation, have been mentioned as a possible side effect, they have rarely been reported in the literature. Read More

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January 2021

Superficial Basal Cell Carcinoma of the Face Successfully Treated with Ingenol Mebutate 0.05% Gel: Case Report and a Review of the Literature.

J Clin Aesthet Dermatol 2020 Oct 1;13(10):28-31. Epub 2020 Oct 1.

Dr. Rosen and Ms. Lowery are with the Department of Dermatology at the Baylor College of Medicine in Houston, Texas.

A 64 year-old Caucasian male patient with a long history of ultraviolet light exposure and multiple actinic keratoses presented with a large, erythematous, and scaly plaque on his forehead. Biopsies revealed superficial basal cell carcinoma (sBCC). Because the patient wanted the shortest possible topical regimen, his sBCC was treated with two overnight ingenol mebutate (IM) 0. Read More

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October 2020

Giant Condyloma Acuminatum Treated Successfully with Mild Local Hyperthermia: Two Case Reports.

Acta Derm Venereol 2021 Feb 11;101(2):adv00391. Epub 2021 Feb 11.

Department of Dermatology, The First Hospital of China Medical University and Key Laboratory of Immunodermatology, 110001 Shenyang, China.

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February 2021

Cauliflower-shaped lesions on a young woman's vulva.

Int J STD AIDS 2021 Mar 3;32(4):378-381. Epub 2021 Feb 3.

Department of Dermatology and Venereology, 36639The First Affiliated Hospital of Anhui Medical University, Hefei, China.

A 20-year-old young woman with cauliflower-shaped lesions on her vulva was misdiagnosed as condyloma acuminatum. Further evaluation revealed positive serological tests for syphilis. On histological examination, and numerous plasma cells were seen to infiltrate the dermis heavily. Read More

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Treatment of intra-anal warts with imiquimod 5% cream: A single-center prospective open study.

J Dermatol 2021 Apr 18;48(4):476-480. Epub 2021 Jan 18.

Department of Dermatology, Tokyo Medical University, Tokyo, Japan.

Intra-anal warts are frequently recalcitrant to surgical removal, but imiquimod 5% cream is not formulated to use in clinical practice due to the risk of mucosal inflammation. In the present, prospective, open study examining the efficacy and safety of imiquimod 5% cream, the drug was applied to the entire inner surface of the anal canal with a cotton swab under anoscopy three times weekly for 16 weeks. If complete remission was not achieved, the treatment was continued until week 28. Read More

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Human Papillomavirus-type distribution in anogenital lesions of prepubertal children.

J Eur Acad Dermatol Venereol 2021 May 5;35(5):1219-1225. Epub 2021 Feb 5.

Department of Dermatology, Venereology, and Allergology, HELIOS St. Elisabeth Hospital Oberhausen, University of Witten-Herdecke, Oberhausen, Germany.

Background: In contrast to adults, only limited data are available on the human papillomavirus (HPV)-type spectrum in anogenital warts (AGW) of children.

Objective: This study aimed to evaluate the HPV-type spectrum in AGW of prepubertal children.

Materials & Methods: In a retrospective German multicentre study, HPV genotyping was performed in AGW biopsies of 55 1- to 12-year-old children using HPV group-specific PCRs followed by hybridization with type-specific probes or sequence analysis. Read More

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Long-term relapse-free treatment with endoscopic submucosal dissection combined with magnifying narrow-band imaging for a pregnant patient with flat-type condyloma acuminatum: a case report.

Clin J Gastroenterol 2021 Apr 4;14(2):439-445. Epub 2021 Jan 4.

Department of Gastroenterology, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan.

Condyloma acuminatum, in the form of genital warts, usually results from an infection by human papillomavirus, one of the most common causes of sexually transmitted diseases. It develops after an incubation period of 3 weeks to 8 months after infection; flat lesions are significantly rare. Condyloma acuminatum is prevalent in the genitals, particularly in the anus of immunodeficient patients. Read More

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[Human papillomavirus infection in men with condyloma acuminatum: Genotype analysis of 70 cases].

Zhonghua Nan Ke Xue 2020 Nov;26(10):906-910

Department of Andrology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266001, China.

Objective: To investigate the distribution of the gene subtypes of human papillomavirus (HPV) in male patients with condyloma acuminatum (CA) and analyze the characteristics of the gene subtypes.

Methods: We extracted genomic DNA of the HPV virus from the genital tissue of 70 male CA patients, detected the DNA subtypes of HPV using the PCR-reverse dot hybridization technique, and analyzed the rates of different subtypes identified and their characteristics of distribution in different age groups.

Results: The male HPV-positive patients were mainly infected at the age of 20-39 years, primarily with high- and low-risk mixed infection of various subtypes, which accounted for 61. Read More

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November 2020

Risk factors of HIV infection among female entertainment workers in Cambodia: Findings of a national survey.

PLoS One 2020 21;15(12):e0244357. Epub 2020 Dec 21.

KHANA Center for Population Health Research, Phnom Penh, Cambodia.

Background: Cambodia has been well recognized for its success in the fight against the HIV epidemic. However, challenges remain in eliminating HIV infections in key populations, including women working in entertainment establishments, such as massage parlors, karaoke bars, or beer gardens. This study explored the prevalence of HIV and identified factors associated with HIV infection among female entertainment workers (FEWs) in Cambodia. Read More

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[Prevention of HPV-induced diseases by prophylactic vaccination].

Hautarzt 2021 Feb 18;72(2):106-113. Epub 2020 Dec 18.

Klinik für Dermatologie, Venerologie und Allergologie, HELIOS St. Elisabeth Klinik Oberhausen, Universität Witten/Herdecke, Josefstr. 3, 46045, Oberhausen, Deutschland.

Human papillomavirus (HPV) infections belong to the most frequent viral infections. Besides benign common warts and benign and malignant lesions of the head and neck area, HPV can induce anogenital dysplasias and cancers. Since the year 2007, effective and safe prophylactic HPV vaccines are licensed in Europe. Read More

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February 2021

Podophyllotoxin Exposure Causes Spindle Defects and DNA Damage-Induced Apoptosis in Mouse Fertilized Oocytes and Early Embryos.

Front Cell Dev Biol 2020 19;8:600521. Epub 2020 Nov 19.

Reproductive Medicine Center, The Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China.

Podophyllotoxin (PPT) is a kind of lignans extracted from the roots and stems of the genus from the tiller family, and it has been widely used in the treatment of condyloma acuminatum, multiple superficial epithelioma in the clinics. However, PPT has been reported to be toxic and can cause liver defects and other organ poisoning. In addition, emerging evidences also indicate that PPT has reproductive toxicity and causes female reproduction disorders. Read More

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November 2020

Opportunistic detection of anal intraepithelial neoplasia at colonoscopy.

JGH Open 2020 Dec 14;4(6):1207-1210. Epub 2020 Oct 14.

School of Health and Medical Sciences University of Western Australia Perth Western Australia Australia.

Background And Aim: Human papilloma virus-associated anal intraepithelial neoplasia (AIN) precedes most anal cancers and can be detected at colonoscopy. We aimed to quantify AIN detection rates in a general population undergoing colonoscopy.

Methods: A retrospective review of a community-based practice for 2 years until December 2019 was conducted. Read More

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December 2020

Laser therapy in cutaneous and genital warts: A review article.

Dermatol Ther 2021 Jan 29;34(1):e14671. Epub 2020 Dec 29.

Department of Dermatology, Kerman University of Medical Sciences, Kerman, Iran.

Traditional treatment modalities for wart require long-term treatment course and usually have high recurrence rates and unwanted side effects. In this review article, we evaluated different types of laser therapy in the treatment of warts. Published articles since 2000 up to July 2020 about laser therapy in genital and non-genital warts were searched and assessed. Read More

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January 2021

[An unusual case of condylomata acuminata identified in the nasal cavity of a patient living in Yaoundé, Cameroon: a clinical report and literature review].

Pan Afr Med J 2020 26;36:349. Epub 2020 Aug 26.

Service Oto-Rhino-Laryngologie et Chirurgie Cervico-Faciale du Centre Hospitalier Universitaire de Yaoundé, Yaoundé, Cameroun.

Condylomata acuminata are sexually transmitted lesions caused by human papillomavirus. They mainly occur in the anogenital area and exceptionally in the nasal cavity. We here report a new case of uncommon detection. Read More

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January 2021

Time-trend of hospitalizations for anogenital warts in Veneto region in the HPV vaccination era: a cross sectional study (2007-2018).

BMC Infect Dis 2020 Nov 18;20(1):857. Epub 2020 Nov 18.

Department of Cardiac Thoracic Vascular Sciences and Public Health, University of Padua, Padua, Italy.

Background: Human papillomavirus (HPV) is a common sexually transmitted pathogen and the cause of several cancers and of anogenital warts. With this study, we estimated the trend of hospitalizations for anogenital warts (AGWs) in the Veneto region (Italy) from 2007 to 2018.

Methods: The analysis included all the hospital discharge records of public and accredited private hospitals occurred in Veneto residents in the timespan 2007-2018. Read More

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November 2020

Autophagy is induced in human keratinocytes during human papillomavirus 11 pseudovirion entry.

Aging (Albany NY) 2020 11 16;12(22):23017-23028. Epub 2020 Nov 16.

Department of Dermatology and Venereology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China.

Human papillomavirus type 11 (HPV11) is one of the main causes of condyloma acuminatum, a widespread sexually transmitted disease. During infection of its primary target cell, keratinocytes, it is likely to encounter the autophagy pathway, which is an intracellular maintenance process that is also able to target invading pathogens. It is currently unknown whether HPV11 is targeted by autophagy or whether it is able to escape autophagy-mediated killing. Read More

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November 2020