5,599 results match your criteria Condyloma Acuminatum


Treatment of multi-position condyloma acuminatum with topical CO laser combined photodynamic therapy - Report of 6 cases.

Photodiagnosis Photodyn Ther 2019 Jan 28. Epub 2019 Jan 28.

Department of Dermatology, Affiliated Hospital of Qingdao University, Qingdao, China.

Background: Condyloma acuminatum(CA)is a venereal disease associated with a high rate of recurrence due to the rapid replication and subtle immune escape mechanism of Human Papillomavirus(HPV). Topical CO laser can remove verruca accurately. Photodynamic therapy with 5-aminolevulinic acid(PDT-ALA) is an effective therapy which targets on HPV infected sites. Read More

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http://dx.doi.org/10.1016/j.pdpdt.2019.01.030DOI Listing
January 2019
1 Read

Incidence of external genital lesions related to human papillomavirus among Mexican men. A cohort study.

Salud Publica Mex 2018 Nov-Dic;60(6):633-644

Center for Infection Research in Cancer, Moffitt Cancer Center and Research Institute.Tampa, Florida.

Objective: To determine external genital lesion (EGL) incidence -condyloma and penile intraepithelial neoplasia (PeIN)- and genital HPV-genotype progression to these EGLs.

Materials And Methods: Participants (healthy males 18- 74y from Cuernavaca, Mexico, recruited 2005-2009, n=954) underwent a questionnaire, anogenital examination, and sample collection every six months;including excision biopsy on suspicious EGL with histological confirmation.Linear array assay PCR characterized 37 high/low-risk HPV-DNA types. Read More

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http://dx.doi.org/10.21149/8461DOI Listing
December 2016
2 Reads

HPV-Related Papillary Lesions of the Oral Mucosa: A Review.

Authors:
Sasha J Betz

Head Neck Pathol 2019 Jan 29. Epub 2019 Jan 29.

Division of Anatomic Pathology, Naval Medical Center San Diego, 34800 Bob Wilson Drive, San Diego, CA, 92134-5000, USA.

Human papillomaviruses (HPVs) are causative of a group of clinically papillary lesions. The HPV-related lesions of the oral cavity include squamous papilloma, condyloma acuminatum, verruca vulgaris, and multifocal epithelial hyperplasia. Benign entities, such as verruciform xanthoma or giant cell fibroma, as well as malignancies, such as papillary squamous cell carcinoma and verrucous carcinoma, may be considered in the clinical and/or histologic differential diagnoses of these lesions. Read More

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http://dx.doi.org/10.1007/s12105-019-01003-7DOI Listing
January 2019
8 Reads

[Advancement in phodynamic therapy for non-neoplastic skin diseases].

Zhong Nan Da Xue Xue Bao Yi Xue Ban 2018 Dec;43(12):1380-1383

Department of Cardiovascular Surgery, Second Xiangya Hospital, Central South University, Changsha 410011, China.

Photodynamic therapy is mainly used in dermatology to treat skin tumors, precancerous lesions, and condyloma acuminatum. Due to its excellent tissue selectivity, easy operation and good cosmetic effect, it has been gradually applied to the treatment of various non-neoplastic skin diseases, such as verruca acuminata, acne, rosacea, chronic skin ulcer, fungal diseases, keloid, and so on. Here is the review on the advancement in photodynamic therapy for non-neoplastic skin diseases. Read More

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http://dx.doi.org/10.11817/j.issn.1672-7347.2018.12.016DOI Listing
December 2018
1 Read

Prevalence and incidence of genital warts and cervical Human Papillomavirus infections in Nigerian women.

BMC Infect Dis 2019 Jan 7;19(1):27. Epub 2019 Jan 7.

Greenebaum Comprehensive Cancer Center, University of Maryland School of Medicine, Baltimore, MD, USA.

Background: Genital warts are important causes of morbidity and their prevalence and incidence can be used to evaluate the impact of HPV vaccination in a population.

Methods: We enrolled 1020 women in a prospective cohort study in Nigeria and followed them for a mean (SD) of 9 (4) months. Nurses conducted pelvic examinations and collected ectocervical samples for HPV testing. Read More

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https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128
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http://dx.doi.org/10.1186/s12879-018-3582-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323853PMC
January 2019
5 Reads
2.613 Impact Factor

Treatment of condyloma acuminatum using combination of laser ablation and ALA-PDT.

Photodiagnosis Photodyn Ther 2018 Dec 20. Epub 2018 Dec 20.

Department of Dermatology, the First Affiliated Hospital of Harbin Medical University, Harbin, 150001, China. Electronic address:

Background: Human papilloma virus (HPV) infection and condyloma acuminatum (CA) in the genital area are often existence in extensive and multi-point fashion. Laser ablation combined with topical photodynamic therapy (PDT) is a feasible approach for genital CA but its effectiveness and limitation need to be evaluated.

Methods: This single-arm prospective study consisted of 100 newly diagnosed CA cases of both sexes. Read More

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http://dx.doi.org/10.1016/j.pdpdt.2018.12.006DOI Listing
December 2018
16 Reads

Condyloma Acuminata Presenting as Isolated Papillary Lesions in the Prostatic Urethra.

Am J Case Rep 2018 Dec 22;19:1522-1525. Epub 2018 Dec 22.

Department of Pathology, Quillen College of Medicine, East Tennessee State University, Johnson City, TN, USA.

BACKGROUND A condyloma acuminatum is a sexually transmitted, human papillomavirus (HPV) associated, neoplasm. In men, it is predominantly found on external genitalia and rarely progresses more proximally than the distal penile urethra. Condyloma acuminata of the prostatic urethra are rare and are usually seen as an extension of, or in association with external lesions. Read More

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http://dx.doi.org/10.12659/AJCR.911682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320550PMC
December 2018
4 Reads

Extensive anogenital warts: a multidisciplinary surgical management.

Pan Afr Med J 2018 26;30:227. Epub 2018 Jul 26.

Department of Urology-Oncology, "Theageneio" Cancer Hospital of Thessaloniki, Thessaloniki, Greece.

Genital warts are a major worldwide healthcare problem of sexually active population. Apart from direct association with cervical cancer, male patients experience HPV-related condylomata in several locations in the anogenital area. Extensive growth, multifocality and difficult accessibility wart sites are demanding and often require multidisciplinary surgical management. Read More

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http://www.panafrican-med-journal.com/content/article/30/227
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http://dx.doi.org/10.11604/pamj.2018.30.227.16448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295299PMC
January 2019
4 Reads

Recurrent oral squamous papilloma in a pediatric patient: Case report and review of the literature.

Niger J Clin Pract 2018 Dec;21(12):1674-1677

Department of Oral and Maxillofacial Pathology/Biology, Lagos University Teaching Hospital, Lagos, Nigeria.

Squamous papillomas are common lesions of the oral mucosa. They are benign proliferating lesions often painless, slow growing and with a cauliflower appearance. However, its clinical appearance which sometimes mimics exophytic carcinoma, verrucous carcinoma or condyloma acuminatum raises concern when it occurs in the oral cavity. Read More

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http://dx.doi.org/10.4103/njcp.njcp_407_17DOI Listing
December 2018
1 Read

Distinction of Condylomata Acuminata from Vulvar Vestibular Papules or Pearly Penile Papules Using Ki-67 Immunostaining.

J Cutan Med Surg 2018 Dec 17:1203475418819992. Epub 2018 Dec 17.

1 Departments of Dermatology and Skin Science, University of British Columbia, Vancouver, Canada.

Background:: Ki-67 is an immunohistochemical stain used as a nuclear proliferation marker. It is nonspecific, and is expressed in all active phases of the cell cycle. Vulvar vestibular papules in women and pearly penile papules in men are benign fibrous papules on the genitals, are noninfectious, and do not require treatment. Read More

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http://dx.doi.org/10.1177/1203475418819992DOI Listing
December 2018
5 Reads

Squamous cell carcinoma of the anal canal.

Curr Probl Cancer 2018 Sep 23;42(5):486-492. Epub 2018 Nov 23.

Brigham and Women's Hospital, Boston, Massachusetts.

Anal squamous cell carcinoma (SCC) is a rare cancer and accounts for approximately 4% of all cancers of the lower alimentary tract. The dominant etiology is infection with human papilloma virus (HPV), which is the most common sexually transmitted disease in the United States. Integration of HPV DNA into the host genome seems to be the driving mechanism behind carcinogenesis. Read More

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http://dx.doi.org/10.1016/j.currproblcancer.2018.11.001DOI Listing
September 2018
5 Reads

Ingenol mebutate for the treatment of anogenital condylomata acuminata.

Clin Exp Dermatol 2018 Nov 20. Epub 2018 Nov 20.

Department of Dermatology, Hospital General Universitario de Valencia, Valencia, Spain.

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http://dx.doi.org/10.1111/ced.13840DOI Listing
November 2018
1 Read

Perspective Clinical Study on Effect of 5-Aminolevulinic Acid Photodynamic Therapy (ALA-PDT) in Treating Condylomata Acuminata in Pregnancy.

Photodiagnosis Photodyn Ther 2018 Nov 14. Epub 2018 Nov 14.

Department of Dermatology of the First Affiliated Hospital of PLA General Hospital, Beijing 100048, China.

Objective: To observe the clinical efficacy of 5-aminolevulinic acid photodynamic therapy (ALA-PDT) in treating vulval condylomata acuminata (CA) in pregnancy.

Methods: The clinical efficacies of ALA-PDT on 16 cases of CA in pregnancy as well as cryotherapy on 22 cases of CA in pregnancy were analyzed in this prospective study.

Results: The treatment group showed a wart clearance rate of 93. Read More

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http://dx.doi.org/10.1016/j.pdpdt.2018.11.012DOI Listing
November 2018
2 Reads

5-aminolevulinic acid photodynamic therapy for condyloma acuminatum of urethral meatus.

J Dermatolog Treat 2018 Nov 14:1-18. Epub 2018 Nov 14.

a Department of Dermatology and Venereology , Nanfang hospital, Southern Medical University , Guangzhou , 510515 , China.

Condyloma acuminatum are the most common sexually transmitted diseases worldwide, and they are closely associated with human papillomavirus (HPV) infections. Urethral meatus warts are uncommon. And many treatments are limited by a difficult approach, recurrences, and potential complications. Read More

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https://www.tandfonline.com/doi/full/10.1080/09546634.2018.1
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http://dx.doi.org/10.1080/09546634.2018.1544406DOI Listing
November 2018
13 Reads

[Research progression of prophylactic HPV vaccine application].

Authors:
L Zhang F H Zhao

Zhonghua Zhong Liu Za Zhi 2018 Oct;40(10):724-728

Department of Cancer Epidemiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.

Prophylactic HPV vaccine was a milestone in the prevention and control of HPV-related diseases, especially cervical cancer. The first HPV vaccine has been marketed in the world for more than 10 years. The follow-up study of HPV vaccine clinical trials further confirms the effectiveness and safety. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0253-3766.2018.10.002DOI Listing
October 2018
1 Read

A Phase 2 Controlled Study of SB206, a Topical Nitric Oxide-Releasing Drug for Extragenital Wart Treatment.

J Drugs Dermatol 2018 Oct;17(10):1100-1105

Background: Nitric oxide (NO), a free radical gas, is endogenously produced in human cells. In high concentration, NO neutralizes many disease-causing microbes. The topical investigational drug SB206 releases NO and has the potential to treat skin diseases caused by viruses. Read More

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October 2018
7 Reads

[HPV infection in women : Diagnostics, treatment and the relevance of vaccination].

Urologe A 2018 Dec;57(12):1445-1451

Frauenklinik der Technischen Universität München, Klinikum rechts der Isar, Ismaninger Str. 22, 81765, München, Deutschland.

Background: Benign, premalignant and malignant changes in the anogenital region, as in the oropharynx are often affected by a persistent HPV infection. Since a causal therapy isn't possible, the focus is on early diagnosis of dysplasia. Better knowledge of the human papilloma virus led to the development of the HPV vaccine and now primary prevention of cancer is possible. Read More

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http://dx.doi.org/10.1007/s00120-018-0795-zDOI Listing
December 2018
5 Reads

Extragenital condyloma acuminatum in the left axillary vault.

JAAD Case Rep 2018 Oct 11;4(9):947-949. Epub 2018 Oct 11.

Division of Dermatology, Washington University School of Medicine, St Louis, Missouri.

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http://dx.doi.org/10.1016/j.jdcr.2018.07.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191947PMC
October 2018
2 Reads

Therapeutic effect of photodynamic therapy combined with imiquimod in the treatment of anal condyloma acuminatum and its effect on immune function.

Exp Ther Med 2018 Nov 3;16(5):3909-3912. Epub 2018 Sep 3.

Department of Dermatology, Liaocheng People's Hospital, Liaocheng, Shandong 252000, P.R. China.

Therapeutic effect of photodynamic therapy combined with imiquimod in the treatment of anal condyloma acuminatum (CA) was investigated to explore its effect on immune function. A total of 104 patients with anal CA were randomly divided into two groups: Patients in the study group were treated with photodynamic therapy combined with imiquimod, and ii) patients in the control group were treated with recombinant human interferon α-2b cream. Clinical efficacy and immune function related indicators were compared between the two groups. Read More

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http://dx.doi.org/10.3892/etm.2018.6676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176148PMC
November 2018
2 Reads

Treatment of giant condyloma acuminatum of the anus. State of the art.

Ann Ital Chir 2018 ;89:291-294

Giant condyloma acuminatum (GCA) is a rare cauliflower-like lesion, also known as Buschke-L ewenstein tumor (BLT). Although characterized by benign histological features, the local behavior of GCA is extremely aggressive, showing progressive infiltration of the surrounding structures leading to tissue destruction by compression. As the correlation between HPV and GCA development grew stronger, the majority of the Authors came to the conclusion that HPV can not only cause CA but, associated with particular risk factors, it can lead to much more serious conditions such as BLT. Read More

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January 2018
3 Reads

Condyloma Acuminata of the Urethra in a Male Renal Transplant Recipient: A Case Report.

Transplant Proc 2018 Oct 20;50(8):2553-2557. Epub 2018 Mar 20.

Department of Urology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan; Department of Advanced Transplant and Regenerative Medicine, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.

Background: Condyloma acuminatum (CA) is a common sexually transmitted disease associated with human papilloma virus (HPV). CA occurring in the urethra is rare and has not been reported in male renal transplant recipients. In addition, despite immunosuppressive conditions and increased risk of HPV-related malignant neoplasms in transplant recipients, HPV testing in male transplant recipients has been uncommon. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00411345183044
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http://dx.doi.org/10.1016/j.transproceed.2018.02.182DOI Listing
October 2018
7 Reads

Ingenol mebutate induces a tumor cell-directed inflammatory response and antimicrobial peptides thereby promoting rapid tumor destruction and wound healing.

Eur J Med Res 2018 Sep 28;23(1):45. Epub 2018 Sep 28.

Department of Dermatology, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.

Background: Ingenol mebutat (IM)-gel is effective for the topical treatment of epithelial tumors, including actinic keratoses (AKs) or anogenital warts (AGW). AK patients treated with IM develop intensified inflammatory reactions on sights of prior clinical visible or palpable AKs as compared to the surrounding actinically damaged skin, suggesting the induction of a tumor cell-directed inflammation. AGW patients treated with IM develop even stronger inflammatory reactions with large erosions, suggesting a directed inflammatory response against HPV-infected keratinocytes. Read More

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http://dx.doi.org/10.1186/s40001-018-0343-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161468PMC
September 2018
5 Reads

Prevalence and treatment of sexually transmitted infections in men followed by urologists in Germany - a cross sectional study with 347,090 men.

Ger Med Sci 2018 13;16:Doc03. Epub 2018 Aug 13.

Epidemiology, QuintilesIMS, Frankfurt, Germany.

The goal of this retrospective analysis was to study the prevalence and treatment of the most common sexually transmitted infections (STI) in men followed by urologists in Germany. This study included a total of 347,090 men followed in 71 urology practices in Germany between 2013 and 2015. The first outcome was the prevalence of individuals diagnosed with STI between 2013 and 2015. Read More

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http://www.egms.de/en/journals/gms/2018-16/000265.shtml
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http://dx.doi.org/10.3205/000265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124731PMC
January 2019
5 Reads

Loss of miR-143 and miR-145 in condyloma acuminatum promotes cellular proliferation and inhibits apoptosis by targeting NRAS.

R Soc Open Sci 2018 Aug 29;5(8):172376. Epub 2018 Aug 29.

Department of Dermatology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, People's Republic of China.

The expression profile of miRNAs and their function in condyloma acuminatum (CA) remains unknown. In this study, we aimed to detect the effects of miR-143 and miR-145, the most downregulated in CA samples using high-throughput sequencing, on cell proliferation and apoptosis, to determine a novel therapeutic target for CA recurrence. RT-qPCR was used to validate the lower expression of miR-143 and miR-145 in a larger size of CA samples, and the expression of NRAS in CA samples was significantly higher than self-controls as determined by western blotting assay. Read More

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http://dx.doi.org/10.1098/rsos.172376DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124073PMC
August 2018
4 Reads

5-aminolevulinic acid photodynamic therapy for anal canal condyloma acuminatum: A series of 19 cases and literature review.

Photodiagnosis Photodyn Ther 2018 Sep 6;23:230-234. Epub 2018 Jul 6.

Department of Dermatology and Venereology, Nanfang hospital, Southern Medical University, Guangzhou, 510515, China. Electronic address:

Background: Anal canal condyloma acuminata are common, sexually transmitted lesions, most often caused by the human papillomavirus. The relatively high recurrence rate of anal canal condyloma acuminata can be attributed to the unsuccessful elimination of viruses in areas of subclinical and latent infection. This study aimed to observe and evaluate the effectiveness of 5-aminolevulinic acid-photodynamic therapy combined with monitoring of human papillomavirus load changes in patients with anal canal condyloma acuminata. Read More

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http://dx.doi.org/10.1016/j.pdpdt.2018.06.022DOI Listing
September 2018
2 Reads
2.010 Impact Factor

Verruciform and Condyloma-like Squamous Proliferations in the Anogenital Region.

Authors:
May P Chan

Arch Pathol Lab Med 2018 Sep 11. Epub 2018 Sep 11.

From the Department of Pathology, University of Michigan Health System, Ann Arbor.

Context: - Histologic distinction between condyloma acuminatum and various benign and malignant condyloma-like lesions in the anogenital area poses a common diagnostic challenge to pathologists across subspecialties.

Objective: - To review the overlapping and distinguishing features of condyloma acuminatum and its mimics, and to clarify confusing terminology and diagnostic criteria for problematic entities.

Data Sources: - A review of the literature on condyloma acuminatum (ordinary and giant types), verrucous carcinoma, warty/warty-basaloid high-grade squamous intraepithelial lesion and squamous cell carcinoma, papillary squamous cell carcinoma, bowenoid papulosis, verruca vulgaris, epidermolytic acanthoma, and verruciform xanthoma was performed. Read More

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http://dx.doi.org/10.5858/arpa.2018-0039-RADOI Listing
September 2018
8 Reads

Successful treatment of giant condyloma in a pediatric heart transplant recipient with topical cidofovir.

Transpl Infect Dis 2018 Dec 28;20(6):e12989. Epub 2018 Sep 28.

Department of Pediatrics, Division of Infectious Diseases, University of Texas Southwestern Medical Center, Dallas, Texas.

We report a case of giant condyloma that developed in a pediatric heart transplant recipient. This infection progressed for several months despite reduction in immunosuppression, topical treatment, and oral cimetidine therapy. Complete resolution was observed following 7 months of topical cidofovir, without evidence of systemic toxicity or rejection. Read More

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http://doi.wiley.com/10.1111/tid.12989
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http://dx.doi.org/10.1111/tid.12989DOI Listing
December 2018
25 Reads

Multimodality Imaging Review of Anorectal and Perirectal Diseases With Histological, Endoscopic, and Operative Correlation, Part I: Anatomy and Neoplasms.

Curr Probl Diagn Radiol 2018 Jul 29. Epub 2018 Jul 29.

Department of Radiology, Louisiana State University Health Shreveport, Shreveport, LA.

A broad spectrum of pathology affects the rectum, anus, and perineum and understanding of its relevant anatomy is important in accurate reporting, particularly in rectal cancer. In this pictorial essay, correlative imaging, endoscopic, pathologic, and operative images are presented to illustrate normal anorectal anatomy and neoplastic conditions that affect the anus and rectum. A particular case-based focus is given to rectal adenocarcinoma with pelvic MR and surgical histopathology. Read More

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http://dx.doi.org/10.1067/j.cpradiol.2018.07.015DOI Listing
July 2018
16 Reads

The role of regulatory T cells in pathogenesis and therapy of human papillomavirus-related diseases, especially in cancer.

Infect Genet Evol 2018 Nov 29;65:406-413. Epub 2018 Aug 29.

Department of Dermatology and Venereology, Nanfang hospital, Southern Medical University, Guangzhou, 510515, China. Electronic address:

Human papillomavirus (HPV) is the most common sexually transmitted agent in the world. It can cause condyloma acuminatum, anogenital malignancies, and head and neck cancers. The host immune responses to HPV involve multiple cell types that have regulatory functions, and HPV-mediated changes to regulatory T cells (Tregs) in both the local lesion tissues and the circulatory system of patients have received considerable attention. Read More

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http://dx.doi.org/10.1016/j.meegid.2018.08.014DOI Listing
November 2018
7 Reads

[Clinicopathological features and management of penile verrucous carcinoma].

Zhonghua Nan Ke Xue 2018 Janurary;24(1):62-66

Department of Urology, Henan Provincial People's Hospital / People's Hospital of Zhengzhou University, Zhengzhou, Henan 450003, China.

Objective: To explore the clinicopathological characteristics, diagnosis and treatment of penile verrucous carcinoma (VC).

Methods: We retrospectively analyzed the clinical data about 18 penile VC patients at the mean age of 52 (35-66) years. The tumors were cauliflower-like, measuring 2. Read More

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November 2018
18 Reads

Treatment of intraurethral condylomata acuminata with surgery and cidofovir instillations in two immunocompromised patients and review of the literature.

Antiviral Res 2018 Oct 25;158:238-243. Epub 2018 Aug 25.

Department of Urology, University Hospitals Leuven, Leuven, Belgium.

Condylomata acuminata (CA) or anogenital warts are benign proliferative lesions caused by low-risk human papillomaviruses (HPV). Treating CA can be very frustrating for patients and clinicians due to the high recurrence rates. Immunosuppression is associated with larger size of CA that are more frequently resistant to treatment. Read More

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http://dx.doi.org/10.1016/j.antiviral.2018.08.016DOI Listing
October 2018
17 Reads

Condylomata Acuminata (Anogenital Warts) Contain Accumulations of HIV-1 Target Cells That May Provide Portals for HIV Transmission.

J Infect Dis 2019 Jan;219(2):275-283

Department of Obstetrics and Gynecology, Boston University School of Medicine, Boston.

Background: Condylomata acuminata (anogenital warts [AGWs]) are prevalent in human immunodeficiency virus (HIV)-infected individuals and sexually active populations at risk for HIV acquisition and have been associated with HIV transmission. We compared AGW specimens to control tissue specimens for abundance, types, and location of HIV target cells and for susceptibility to HIV infection in vitro, to provide biologic evidence that AGWs facilitate HIV transmission.

Methods: We used immunohistologic staining to identify HIV target cells in AGW and control specimens. Read More

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http://dx.doi.org/10.1093/infdis/jiy505DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306021PMC
January 2019
11 Reads

Human Papillomavirus-Associated Invasive Condylomas in a Man with Immunosuppressive Comorbidities.

Urol Int 2018 Aug 21:1-5. Epub 2018 Aug 21.

Department of Urology and Pediatric Urology, Saarland University, Homburg, Germany.

Human papilloma virus (HPV) infections are one of the most common sexually transmitted diseases. We present the case of a 77-year-old Caucasian male with enormous genital warts of the penis, scrotum, groins and anus. Lesions were excised by electrosurgery. Read More

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http://dx.doi.org/10.1159/000491098DOI Listing
August 2018
23 Reads

Giant condyloma acuminatum of the vulva: Successful management with imiquimod.

JAAD Case Rep 2018 Aug 15;4(7):692-694. Epub 2018 Aug 15.

Department of Obstetrics and Gynecology, Angers University Hospital, Angers, France.

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http://dx.doi.org/10.1016/j.jdcr.2018.04.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098202PMC
August 2018
19 Reads

Cantharidin is Superior to Trichloroacetic Acid for the Treatment of Non-mucosal Genital Warts: A Pilot Randomized Controlled Trial.

Clin Exp Obstet Gynecol 2018 ;45(3):383-386

Department of Obstetrics and Gynecology, University of New Mexico, Albuquerque, NM.

Condyloma Acuminatum is a sexually transmitted viral disease caused by the human papilloma virus (HPV). It is the most common viral sexually transmitted disease. In this randomized controlled trial, cantharidin was found to be more effective and better tolerated than trichloroacetic acid for the treatment of these lesions. Read More

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http://www.irog.net
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http://dx.doi.org/10.12891/ceog4112.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075835PMC
August 2018
13 Reads

Effectiveness of physically ablative and pharmacological treatments for anal condyloma in HIV-infected men.

PLoS One 2018 1;13(8):e0199033. Epub 2018 Aug 1.

Department of Surgery, University Hospital Germans Trias i Pujol, Badalona, Catalonia, Spain.

Background: There is limited information on the effectiveness of available treatments for anal condyloma acuminata in HIV-1-infected men.

Aim: To provide data on the effectiveness of electrosurgical excision, infrared coagulation and pharmacological (imiquimod) treatments for anal condyloma acuminata (peri-anal and/or intra-anal) in HIV-1-infected men based on authors' practice.

Methods: Single-center, retrospective descriptive analysis of HIV-1-infected men, 18 years or older treated for anal condyloma acuminata. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0199033PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070186PMC
January 2019
5 Reads

Treatment of latent or subclinical Genital HPV Infection with 5-aminolevulinic acid-based photodynamic therapy.

Photodiagnosis Photodyn Ther 2018 Sep 23;23:362-364. Epub 2018 Jul 23.

Department of Dermatology and Venereology, Nanfang hospital, Southern Medical University, Guangzhou 510515, China. Electronic address:

Background: Genital HPV infections are widely prevalent. HPV can persist and be transmitted to partners even after warts are gone. The HPV genotype and viral load assay can reveal whether infections are persistent or latent, and it can serve as a predictor of infection clearance. Read More

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http://dx.doi.org/10.1016/j.pdpdt.2018.07.014DOI Listing
September 2018
2 Reads

[A young man with extensive skin abnormalities].

Ned Tijdschr Geneeskd 2018 May 16;162. Epub 2018 May 16.

GGD Flevoland, Centrum Seksuele Gezondheid, Lelystad.

A 26-year-old man who has sex with men visited the STI clinic because of increasing skin abnormalities since four months. The patient had macular skin lesions on his penis and scrotum, condylomata lata in the anal region, cutaneous lesions on the feet, and a widespread papular rash. A secondary stage of syphilis was diagnosed. Read More

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May 2018
2 Reads

Development of a human papillomavirus type 6/11 vaccine candidate for the prevention of condyloma acuminatum.

Vaccine 2018 08 2;36(32 Pt B):4927-4934. Epub 2018 Jul 2.

Departments of Molecular Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, China. Electronic address:

Condyloma acuminatum (CA) represents a significant human papillomavirus (HPV) disease burden worldwide, resulting in substantial healthcare costs and loss of life quality in both genders. To address this problem, we tried to develop a bivalent HPV6/11 virus-like particle (VLP) vaccine targeting CA. HPV6/11 VLPs were generated in Hansenula polymorpha, and a disassembly and reassembly (D/R) treatment was further conducted to improve the stability and monodispersity of the VLPs. Read More

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http://dx.doi.org/10.1016/j.vaccine.2018.06.041DOI Listing
August 2018
8 Reads

[Treatment of HPV-associated Anal Lesions in HIV-positive Patients - Comparison of Surgical Treatment and Topical Therapy with Imiquimod].

Zentralbl Chir 2018 Jul 3. Epub 2018 Jul 3.

Klinik und Poliklinik für Allgemein-, Viszeral-, Thorax- und Gefäßchirurgie, Universitätsklinikum Bonn, Deutschland.

Objectives: In HIV-patients, routine proctological assessment is warranted due to the high incidence of human papilloma virus (HPV) infection-related anogenital lesions, such as Condylomata acuminata (C. ac.), anal intraepithelial dysplasia (AIN) and anal cancer. Read More

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http://dx.doi.org/10.1055/a-0632-2017DOI Listing
July 2018
22 Reads

Anogenital warts in children: Analysis of a cohort of 34 prepubertal children.

Pediatr Dermatol 2018 Sep 1;35(5):e325-e327. Epub 2018 Jul 1.

Department of Dermatovenereology, Centro Hospitalar de São João, EPE, Porto, Portugal.

Anogenital warts are caused by infection with the human papillomavirus. We reviewed the clinical data of 34 children younger than 13 with anogenital warts referred to the department of dermatovenereology of a tertiary care hospital. Suspicion of sexual abuse was raised in 11 (32. Read More

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http://dx.doi.org/10.1111/pde.13543DOI Listing
September 2018
18 Reads

[Pigmented extramammary Paget's disease accompanied with condyloma acuminatum: a case report].

Beijing Da Xue Xue Bao Yi Xue Ban 2018 Jun;50(3):572-575

Department of Dermatology, Peking University People's Hospital, Beijing 100044, China.

Pigmented extramammary Paget's disease (PEMPD) is an uncommon intraepithelial adenocarcinoma and a rare variant of Paget's disease, characterized as a superficial pigmented scaly macule clinically and an increased number of melanocytes scattered between the Paget's cells histologically. So it may be confused clinically and histologically with melanocytic tumors, dermatitis and other dermatoses. Different therapeutic attitudes are required in this case of adenocarcinoma in situ as opposed to melanoma and dermatitis. Read More

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June 2018
11 Reads

DNAJA4 deficiency enhances NF-kappa B-related growth arrest induced by hyperthermia in human keratinocytes.

J Dermatol Sci 2018 Sep 23;91(3):256-267. Epub 2018 May 23.

China Medical University, Shenyang, 110001, China; Department of Dermatology, No.1 Hospital of China Medical University, China; Key Laboratory of Immunodermatology, Ministry of Health and Ministry of Education, Shenyang, 110001, China. Electronic address:

Background: Hyperthermia is an effective treatment against cancer and human papillomavirus (HPV) infection. Previous studies have shown that heat shock proteins are crucial to the action of hyperthermia.

Objectives: To examine the effects of hyperthermia in combination with DNAJA4-deficiency on human keratinocytes and Condyloma acumunatum (CA) tissues. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09231811183023
Publisher Site
http://dx.doi.org/10.1016/j.jdermsci.2018.05.006DOI Listing
September 2018
8 Reads

Preemptive Analgesia Decreases Pain Following Anorectal Surgery: A Prospective, Randomized, Double-Blinded, Placebo-Controlled Trial.

Dis Colon Rectum 2018 Jul;61(7):824-829

Department of Surgery, University of Vermont Medical Center, Burlington, Vermont.

Background: Postoperative pain is a frequent cause for delayed discharge following outpatient procedures, including anorectal surgery. Both central and peripheral pain receptor sensitization are thought to contribute to postoperative pain. Blocking these receptors and preempting sensitization prevents hyperalgesia leading to lower pain medication requirements. Read More

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http://dx.doi.org/10.1097/DCR.0000000000001069DOI Listing
July 2018
11 Reads

Perianal condyloma acuminatum-like plaque.

Cutis 2018 Apr;101(4):248;255;256;259

Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina, Charleston, USA.

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April 2018
3 Reads

The Impact of Varying Numbers of Quadrivalent Human Papillomavirus Vaccine Doses on Anogenital Warts in the United States: A Database Study.

J Low Genit Tract Dis 2018 Jul;22(3):189-194

Department of Obstetrics & Gynecology, The University of Texas Medical Branch at Galveston, TX.

Objective: The aim of the study was to investigate the effects of 3 or less quadrivalent human papillomavirus (HPV) vaccine doses on anogenital warts in both males and females in the United States.

Materials And Methods: We conducted a retrospective database study that included males and females aged 9 to 26 years who received varying numbers of vaccine doses between 2006 and 2015. The primary outcome was the incidence of anogenital warts starting 3 months after the last dose of the HPV vaccine. Read More

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http://dx.doi.org/10.1097/LGT.0000000000000401DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014903PMC
July 2018
10 Reads

Invasive penile squamous cell carcinoma.

Cutis 2018 Mar;101(3):224-227

Department of Laboratory Medicine, Department of Dermatology, Geisinger Medical Center, Danville, Pennsylvania, USA.

Invasive penile squamous cell carcinoma (PSCC) is a rare malignancy with considerable morbidity and mortality. Because a delayed or incorrect diagnosis can have a devastating outcome, physicians should maintain a high index of clinical suspicion for PSCC in patients presenting with penile lesions, particularly in young or middle-aged patients in whom presentation of PSCC is uncommon. We report the case of a 27-year-old circumcised man who presented with invasive PSCC following a diagnosis of condyloma 8 years prior. Read More

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March 2018
4 Reads

Prevalence and Burden Related to Genital Warts in India.

Viral Immunol 2018 06 2;31(5):346-351. Epub 2018 May 2.

8 Royal Women's Hospital , Melbourne, Australia .

The prevalence of genital warts (GW) and self-reported human papillomavirus (HPV) as well as disease-related psychosocial impact among male and female patients aged 18-60 years in India were assessed. GW prevalence was estimated using a 2-week daily log of patients examined from June 7-September 22, 2011 by 200 participating physicians in 6 regions of India. Psychosocial impact was estimated using one-time, self-administered surveys, including HPV Impact Profile (HIP), Cuestionario Específico para Condiloma Acuminado ([Spanish] CECA; "Specific questionnaire for Condylomata Acuminata") and EuroQol-5 Dimension survey. Read More

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http://dx.doi.org/10.1089/vim.2017.0157DOI Listing
June 2018
20 Reads

Prevalence, incidence and correlates of low risk HPV infection and anogenital warts in a cohort of women living with HIV in Burkina Faso and South Africa.

PLoS One 2018 1;13(5):e0196018. Epub 2018 May 1.

Wits Reproductive Health and HIV Institute, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Objective: To report the prevalence and incidence of low-risk human papillomavirus infection (LR-HPV) and anogenital warts (AGW) among women living with HIV (WLHIV) in Burkina Faso (BF) and South Africa (SA), and to explore HIV-related factors associated with these outcomes.

Methods: We enrolled 1238 WLHIV (BF = 615; SA = 623) aged 25-50 years and followed them at three time points (6, 12 and 16 months) after enrolment. Presence of AGW was assessed during gynaecological examination. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0196018PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929550PMC
July 2018
12 Reads

[Persistent chlamydial genital infection in Tianjin area: An epidemiological study].

Zhonghua Nan Ke Xue 2017 Mar;23(3):223-226

Department of Dermatology, General Hospital of Tianjin Medical University, Tianjin 300052, China.

Objective: To investigate the epidemic features of persistent genital chlamydial infection (GCI) in Tianjin area.

Methods: We statistically analyzed the clinical data about the persistent GCI patients received at the Venereal Disease Clinic of Tianjin Medical University General Hospital from 2009 to 2011.

Results: A total of 158 patients with persistent GCI were received from Tianjin area. Read More

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March 2017
19 Reads