6,080 results match your criteria Condyloma Acuminatum


A new option for the treatment of condyloma acuminatum in the male urethra: Multimodal ultrasound image-guided scraping and photodynamic therapy (USP).

Photodiagnosis Photodyn Ther 2022 Jun 23:102985. Epub 2022 Jun 23.

Department of Dermatology,International Education College of Zhejiang Chinese Medical University,hangzhou,310053,China.

Objectives: Condyloma acuminatum (CA) is a sexually transmitted disease with a high recurrence rate due to the rapid replication of human papillomavirus (HPV) and its subtle immune escape mechanism, which makes the diagnosis and treatment of CA in the male urethra particularly difficult. This study aims to evaluate the efficacy of comprehensive treatments for male urethral CA after accurate localization of warts under ultrasound guidance.

Methods: The study included 15 men with intraurethral CA. Read More

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Diagnostic Pearls of Vulvar Epidermolytic Acanthoma: Case Report.

Ann Dermatol 2022 Jun 20;34(3):221-224. Epub 2022 May 20.

Department of Dermatology, UF Health Dermatology-Springhill, Gainesville, FL, United States.

Epidermolytic acanthomas (EA) are uncommon benign tumors clinically presenting as single to multiple papules. Histologically, EA display hyperkeratosis, hypergranulosis, acanthosis, and epidermal degeneration-also known as epidermolytic hyperkeratosis (EH). EA may be misdiagnosed as condyloma both clinically and histopathologically when located on the genitalia. Read More

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Vulvar condyloma of Buschke and Löwenstein: an unusual tumour in developed countries.

BMJ Case Rep 2022 06 7;15(6). Epub 2022 Jun 7.

Gynecology and Obstetrics, Unidade Local de Saude de Matosinhos EPE, Hospital Pedro Hispano, Matosinhos, Porto, Portugal.

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Rectal Condyloma Acuminatum.

Mayo Clin Proc 2022 Jun;97(6):1156-1157

Department of Gastroenterology and Hepatology, Mie University Hospital, Tsu, Japan.

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Detection of Five Types of HPV Genotypes Causing Anogenital Warts (Condyloma Acuminatum) Using PCR-Tm Analysis Technology.

Front Microbiol 2022 17;13:857410. Epub 2022 May 17.

Department of Laboratory Medicine, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Objectives: Condyloma acuminatum (CA) is a common sexually transmitted disease caused by human papillomavirus (HPV) infection. We established a high-throughput, simple, low-cost, and accurate HPV-typing assay (polymerase chain reaction-melting temperature [PCR-Tm] analysis) to detect HPV in CA.

Materials And Methods: We detected 280 cervical scraping samples, including positive samples of HPV-6 (26), HPV-11 (12), HPV-16 (22), HPV-42 (18), HPV-43 (25), HPV-multiple (19), HPV- other type (58), and HPV-negative samples (100). Read More

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Cryotherapy Combined with Photodynamic Therapy for Successful Treatment of Condyloma Acuminatum in Special Sites Such as the Nipple and the Nasal Vestibule: A Series of Two Case Reports.

Photodiagnosis Photodyn Ther 2022 May 26:102930. Epub 2022 May 26.

The Fourth School of Medicine Affiliated to Zhejiang Chinese Medical University, China. Electronic address:

Condyloma acuminatum is a benign tumor principally resulting from a human papillomavirus type 6 or 11 infection. The lesions mostly damage the genital and perianal squamous epithelium and skin but occasionally emerge outside the perianal and genital regions. We studied the cases of a 29-year-old man with left nasal vestibule vegetation and a 22-year-old woman with left nipple vegetation. Read More

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Efficacy of photodynamic therapy for warts induced by human papilloma virus infection: A systematic review and meta-analysis.

Photodiagnosis Photodyn Ther 2022 May 20:102913. Epub 2022 May 20.

Department of Dermatology, Hangzhou Third People's Hospital; Hangzhou Third Hospital Affiliated to Zhejiang Chinese Medical University; Affiliated Hangzhou Dermatology Hospital, Zhejiang University School of Medicine; West Lake Road 38, Hangzhou, 310009, People's Republic of China. Electronic address:

Background: The incidence of warts caused by human papilloma virus (HPV) infection is very high in the population. Photodynamic therapy (PDT), as an emerging method for wart treatment, has been demonstrated to be effective and safe by an increasing number of studies. This meta-analysis of previous literature aimed to investigate the potential of PDT as a first-line treatment for warts. Read More

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HPV Vaccination: Does It Have a Role in Preventing Penile Cancer and Other Preneoplastic Lesions?

Semin Oncol Nurs 2022 Jun 14;38(3):151284. Epub 2022 May 14.

Department of Urology, University Hospitals Leuven, Leuven, Belgium. Electronic address:

Objectives: Human papillomavirus (HPV) is the most common sexually transmitted infection globally, which causes nearly all cervix carcinomas and contributes to oropharyngeal, penile, vulva, vagina, and anal cancers. Despite the role of HPV in several preneoplastic and cancerous lesions in men, male vaccine coverage is low. This article aims to provide insights into the pathophysiology of HPV-related penile cancer and penile intraepithelial neoplasia (PeIN). Read More

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The Pathogenesis of Giant Condyloma Acuminatum (Buschke-Lowenstein Tumor): An Overview.

Int J Mol Sci 2022 Apr 20;23(9). Epub 2022 Apr 20.

Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Santé et de la Recherche Médicale (INSERM) UMR-1163, Necker Hospital for Sick Children, 75015 Paris, France.

Giant condyloma acuminatum, also known as Buschke-Lowenstein tumor (BLT), is a rare disease of the anogenital region. BLT is considered a locally aggressive tumor of benign histological appearance, but with the potential for destructive growth and high recurrence rates. BLT development is strongly associated with infection with low-risk human papillomaviruses (HPVs), mostly HPV-6 and -11. Read More

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Human papillomavirus genotype distribution of genital keratotic lesions.

Australas J Dermatol 2022 May 11. Epub 2022 May 11.

Department of Dermatology, Kosin University College of Medicine, Busan, Korea.

Genital keratotic lesions include bowenoid papulosis (BP), which histologically resembles squamous cell carcinoma in situ containing high-risk HPV, condyloma acuminatum (CA) that is a genital wart containing mostly low-risk HPV, and genital seborrheic keratosis (GSK), which is a benign epidermal tumour lacking a clear etiologic relationship with HPV. This study compared HPV genotype distributions among BP, CA and GSK and revealed that BP and GSK were related to high-risk HPV whereas CA was related to low-risk HPV. It is plausible that GSK is a distinct epidermal tumour often related to high-risk HPV rather than merely a senescent form of CA considering the overall discrepancy in the frequency distribution of HPV genotypes along with histopathological differences, and the detection of high-risk HPV in GSK alerts physicians to consider more active treatment and continued follow-ups. Read More

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Buschke-Löwenstein tumors: A series of 7 case reports.

Exp Ther Med 2022 Jun 13;23(6):393. Epub 2022 Apr 13.

Department of Dermatology, 'Ponderas' Academic Hospital, 014142 Bucharest, Romania.

Giant condyloma acuminatum (GCA), or Buschke-Löwenstein tumor (BLT), represents an infrequent sexually transmitted disease (STD), caused by human papillomavirus (HPV), especially genotype 6 or 11. There are numerous risk factors for HPV, such as multiple sexual partners, homosexuality, prostitution, chronic genital infections, as well as the lack of proper hygiene. HPV infection is a field infection, where large areas of cells at a tissue surface are affected by the HPV virus; therefore, once the GCA is excised, treatment of the whole affected genital area needs to be undertaken. Read More

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Sexual function and sexual quality of life in men with genital warts: a cross-sectional study.

Reprod Health 2022 Apr 27;19(1):102. Epub 2022 Apr 27.

Department of Midwifery, School of Nursing and Midwifery, Community Based Psychiatric Care Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

Background: Human papillomavirus is the most common sexually transmitted infection, usually passing from one person to another after the first sexual activity. Infection with this virus and the occurrence of genital warts (GWs) could have several effects on patients' health. This study was performed to evaluate the sexual function and sexual quality of life (SQOL) in men with GWs. Read More

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Buske-Lowenstein Tumor: A Rare Cause of Genital Warts.

Cureus 2022 Mar 25;14(3):e23477. Epub 2022 Mar 25.

Emergency Medicine, Envision Physician Services, Plantation, USA.

The Buschke-Löwenstein tumor (BLT), also known as giant condylomata acuminata (GCA), is a pseudo-epithelial proliferation engendered by the human papillomavirus (HPV). Interestingly, its location at the anal margin, or perianal skin, is rare. The authors present the case of a gentleman who became unstable while standing, stating that his ears were ringing. Read More

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Incidence of anogenital warts after the introduction of the quadrivalent HPV vaccine program in Manitoba, Canada.

PLoS One 2022 26;17(4):e0267646. Epub 2022 Apr 26.

Vaccine and Drug Evaluation Centre, Department of Community Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.

Background: The incidence of anogenital warts (AGW) decreased after the introduction of the quadrivalent human papillomavirus (qHPV) vaccine in multiple jurisdictions. We studied how comparing AGW incidence rates with different outcomes affects the interpretation of the qHPV vaccination program. To do this, we replicated multiple study designs within a single jurisdiction (Manitoba). Read More

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Vulvar Verrucous Carcinoma and Genital Condylomatosis.

Curr Health Sci J 2021 Oct-Dec;47(4):602-607. Epub 2021 Dec 31.

Department of Surgery University of Medicine and Pharmacy of Craiova, Romania.

Verrucous carcinoma is a histopathological type of well-differentiated squamous cell carcinoma, clinically characterized by slow and continuous growth, having a local destructive character, but low metastasis potential. Condyloma acuminatum is a sexually transmitted infection caused mainly by subtypes 6 and 11 of HPV, with subtypes 16, 18 being involved in malignant transformation. We present the case of a 70-year-old woman, hospitalized for a vulvar and perineal vegetative, ulcerated, bleeding tumor, with onset 20 years ago. Read More

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December 2021

Condyloma acuminata in under-represented groups: an All of Us database analysis.

Sex Transm Infect 2022 Apr 15. Epub 2022 Apr 15.

Department of Dermatology, Rutgers Robert Wood Johnson Medical School, Piscataway, New Jersey, USA.

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The heterogeneity of Human Papilloma Virus genotypes in the oropharyngeal cavity, anus, and urogenital sites.

New Microbiol 2022 Jan 11;45(1):73-81. Epub 2021 Dec 11.

Translational Medicine, Vanguard and Technology Transfer Sector, Human Health Department, Central ADN Laboratories. Morelia, Michoacán, México, 58341.

The distribution of Human Papilloma Virus (HPV) genotypes is not homogeneous among the infectedcells in a specific anatomical site. Thus, we conducted a prospective cross-sectional studywith 2,130 Mexican men and women aged 16 to 80 years. We described the prevalence of HPVgenotypes at the oropharyngeal cavity, anus, and urogenital sites. Read More

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January 2022

Successful treatment of oral condyloma acuminata with photodynamic therapy: Two case reports.

Photodiagnosis Photodyn Ther 2022 Jun 26;38:102834. Epub 2022 Mar 26.

Department of Dermatology, Institute of Dermatology, Peking University Shenzhen Hospital, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Center, Shenzhen 518036, China.

Oral condyloma acuminatum (OCA) is a less prevalent subtype of condyloma acuminatum and is challenging to treat. We reported two cases of OCA successfully treated with 5-aminolevulinic acid photodynamic therapy (ALA-PDT). After three treatments spaced one week apart, both cases were completely cured without significant adverse reactions and were followed up for one year with no recurrence. Read More

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HPVMD-C: a disease-based mutation database of human papillomavirus in China.

Database (Oxford) 2022 03;2022

College of Life Sciences, Zhejiang Sci-Tech University, Hangzhou 310018, China.

Human papillomavirus (HPV) can cause condyloma acuminatum and cervical cancer. Some mutations of these viruses are closely related to the persistent infection of cervical cancer and are ideal cancer vaccine targets. Several databases have been developed to collect HPV sequences, but no HPV mutation database has been published. Read More

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Asian guidelines for condyloma acuminatum.

J Infect Chemother 2022 Jul 25;28(7):845-852. Epub 2022 Mar 25.

Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, India. Electronic address:

The present guidelines aim to provide comprehensive information on genital condyloma acuminata, including the epidemiology, clinical features, diagnosis and management. The guidelines provide evidence-based recommendations on the diagnosis, prevention and treatment of genital condyloma acuminata in adults in Asia, including patients with HIV co-infection.

Methodology: A PubMed search was performed, using the keywords "condyloma acuminata", "anal wart", "anogenital wart", "genital wart" and "genital HPV". Read More

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Clinical and dermoscopic overlap of genital molluscum contagiosum with condyloma acuminate.

SAGE Open Med Case Rep 2022 22;10:2050313X221086100. Epub 2022 Mar 22.

Department of Dermatology, The First Hospital of Hebei Medical University, Shijiazhuang, P.R. China.

A 24-year-old male presented with asymptomatic penile papules for 1 month. Dermatology examination showed pink, soft papules on the ventral side of the penis, with a clear boundary and rough surface, and papillary hyperplasia could be seen. Dermoscopy revealed multiple finger-like projections without vessels in the center of the lesion under polarized light, and linear and crown-like vessels could be seen at the edge of the lesion. Read More

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Unrecognized Bowen's disease in previously treated condylomata acuminata: indication of a common etiology?

Acta Dermatovenerol Alp Pannonica Adriat 2022 Mar;31(1):33-37

Department of Dermatology and Venereology, Osijek University Hospital, Osijek, Croatia.

Bowen's disease (BD) is an intraepidermal squamous cell carcinoma (SCC) with the capacity to become invasive SCC giving rise to distant metastasis. In rare cases it can be associated with human papillomavirus (HPV) infection, specifically with HPV types 16, 18, 31, 32, and 34. Here we report a case of an immunocompetent white male, age 37, with an erythematous, irregularly-shaped patch in his suprapubic region, appearing 1 year after treatment for condylomata acuminata with cryotherapy and podophyllin in the same area. Read More

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Genital warts and inflammatory bowel diseases: Danish real-world evidence to assess patient-relevant outcomes.

United European Gastroenterol J 2022 04 23;10(3):249-250. Epub 2022 Mar 23.

Department of Gastroenterology, Sorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique, AP-HP, Hôpital Saint-Antoine, Paris, France.

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Investigation of frequency and typing of human papillomavirus among genital warts using a reverse dot blot hybridization approach.

BMC Infect Dis 2022 Mar 22;22(1):278. Epub 2022 Mar 22.

Department of Gynecology and Obstetrics, Medical Faculty, Birjand University of Medical Sciences, Birjand, Iran.

Background: Human papillomavirus (HPV) is the most common sexually transmitted infection worldwide, affecting about 80% of women up to the age of 50. The persistent infection of high risk-HPV types (HR-HPV) is the leading cause of cervical cancer, the fourth most common cancer of women. Therefore, we aimed to evaluate the frequency and typing of HPV in the genital lesions in the Iranian population. Read More

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A Case-Control Study of Photodynamic Therapy Combined with Thymosin in the Treatment of Condyloma Acuminatum in Anal Canal.

J Healthc Eng 2022 12;2022:3019379. Epub 2022 Mar 12.

Department of Infectious Diseases, Wuhan Jinyintan Hospital, Wuhan 43000, China.

A case-control study is performed in this paper to explore various possible effects and clinical value of the photodynamic therapy combined with thymosin for the treatment process of the condyloma acuminatum (CA) in the anal canal. For this purpose, a hundred (100) patients specifically with CA in the anal canal who were regularly treated in the hospital from February 2019 to April 2021 were recruited. The first group, that is, the control group, was treated with thymosin, whereas photodynamic therapy combined with thymosin was used as a treatment for the study group. Read More

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Giant anogenital tumor of Buschke-Löwenstein in a patient living with human immunodeficiency virus/acquired immunodeficiency syndrome: a case report.

J Med Case Rep 2022 Mar 18;16(1):116. Epub 2022 Mar 18.

Department of Internal Medicine and Specialties, Faculty of Medicine and Biomedical Sciences, University of Yaounde I, Yaounde, Cameroon.

Background: Buschke-Löwenstein tumor is a giant condyloma acuminata infection that is characterized by degeneration, invasion, and recurrence. It is associated with human papilloma virus infection. It develops around the genital and perineal area, sometimes causing a large budding ulcerated lesion. Read More

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Clinical Conundrum: A Case of Cervical Giant Condyloma Acuminatum.

J Obstet Gynaecol Can 2022 Mar;44(3):294-297

Allan Blair Cancer Centre, Regina, SK.

Giant condyloma acuminatum (GCA) is a benign anogenital lesion caused by human papilloma virus. It is rarely found on the cervix and is difficult to differentiate from malignancy. It is associated with a propensity for invasion, recurrence, and malignant transformation. Read More

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Increased risk of genital warts in inflammatory bowel disease: A Danish registry-based cohort study (1996-2018).

United European Gastroenterol J 2022 04 16;10(3):287-295. Epub 2022 Mar 16.

PREDICT, Center for Molecular Prediction of Inflammatory Bowel Disease, Faculty of Medicine, Aalborg University, Copenhagen, Denmark.

Background: Patients with inflammatory bowel disease (IBD) are at increased risk of human papillomavirus (HPV) related cancers such as anal squamous cell carcinoma. However, risk of non-malignant HPV infection has never been systematically studied in IBD. This study aims to assess the risk of genital warts (GW) in IBD patients. Read More

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Cost-Effectiveness of Bivalent, Quadrivalent, and Nonavalent HPV Vaccination in South Africa.

Clin Drug Investig 2022 Apr 16;42(4):333-343. Epub 2022 Mar 16.

Fifth Department of Medicine, University Hospital Mannheim, Heidelberg University, Mannheim, Germany.

Background And Objectives: In South Africa, the prevalence of human papillomavirus (HPV) and associated diseases, such as cervical cancer and genital warts, is among the highest in the world. This study evaluates the cost-effectiveness of bivalent, quadrivalent, and nonavalent HPV vaccination for 9- to 14-year-old girls from the South African healthcare system perspective.

Methods: A Markov model portraying the natural HPV disease progression from high-risk infection to cervical intraepithelial neoplasia (CIN) I, CIN II/III, or cervical cancer and from low-risk infection to genital warts was built. Read More

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