6,190 results match your criteria Condyloma Acuminata


Dowling-Degos Disease Localized on Vulva Mimicking Condyloma Acuminata.

Indian J Dermatol 2018 Nov-Dec;63(6):521-522

Department of Dermatology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.

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December 2018
2 Reads

HIV-positive gay men's knowledge and perceptions of Human Papillomavirus (HPV) and HPV vaccination: A qualitative study.

PLoS One 2018 29;13(11):e0207953. Epub 2018 Nov 29.

Toronto General Hospital, Toronto, Canada.

The human papillomavirus (HPV) is the most common sexually transmitted infection worldwide. Gay, bisexual, and other men who have sex with men (GBM) living with HIV are disproportionately impacted by HPV-associated anal cancer, with rates about 100-fold that of the general population. Fortunately, HPV vaccination has proven efficacy in preventing both anogenital warts (condyloma) in males and anal pre-cancers (anal intraepithelial neoplasia; AIN) in GBM up to the age of 26. Read More

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November 2018
4 Reads

Race Is Associated With Burden of Anal Condyloma and Need for Operative Intervention.

J Surg Res 2018 Dec 11;232:629-634. Epub 2018 Aug 11.

Division of Colorectal Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin. Electronic address:

Background: Human papillomavirus is a common sexually transmitted infection that may affect the oropharynx, genitalia, or anus. Some strains of this virus may cause bulky growths around the anus known as giant anal condylomas. These can become large, disfiguring, and may cause bleeding, as well as difficulty with defecation and hygiene. Read More

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December 2018
4 Reads

Ingenol mebutate for the treatment of anogenital condylomata acuminata.

Clin Exp Dermatol 2018 Nov 20. Epub 2018 Nov 20.

Department of Dermatology, Hospital General Universitario de Valencia, Valencia, Spain.

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November 2018
1 Read

Perspective Clinical Study on Effect of 5-Aminolevulinic Acid Photodynamic Therapy (ALA-PDT) in Treating Condylomata Acuminata in Pregnancy.

Photodiagnosis Photodyn Ther 2018 Nov 14. Epub 2018 Nov 14.

Department of Dermatology of the First Affiliated Hospital of PLA General Hospital, Beijing 100048, China.

Objective: To observe the clinical efficacy of 5-aminolevulinic acid photodynamic therapy (ALA-PDT) in treating vulval condylomata acuminata (CA) in pregnancy.

Methods: The clinical efficacies of ALA-PDT on 16 cases of CA in pregnancy as well as cryotherapy on 22 cases of CA in pregnancy were analyzed in this prospective study.

Results: The treatment group showed a wart clearance rate of 93. Read More

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November 2018
1 Read

[Vaccination: Protection for boys against genital warts and cancer via human papillomavirus infection].

Authors:
W Bühmann

Urologe A 2018 Dec;57(12):1499-1508

, Terpstig 55, 25980, Sylt OT Morsum, Deutschland.

Vaccination qualifies as the most effective medical procedure worldwide. Using the example of human papillomavirus(HPV)-associated benign and malignant diseases, the incidence, diagnostics, treatment, particularly however, the option of sustainable elimination of all these entities by achieving herd immunity by a gender balanced inoculation quota of 80% at the age of 9-17 years are shown. Read More

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December 2018
3 Reads

5-aminolevulinic acid photodynamic therapy for condyloma acuminatum of urethral meatus.

J Dermatolog Treat 2018 Nov 14:1-18. Epub 2018 Nov 14.

a Department of Dermatology and Venereology , Nanfang hospital, Southern Medical University , Guangzhou , 510515 , China.

Condyloma acuminatum are the most common sexually transmitted diseases worldwide, and they are closely associated with human papillomavirus (HPV) infections. Urethral meatus warts are uncommon. And many treatments are limited by a difficult approach, recurrences, and potential complications. Read More

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November 2018
6 Reads

A Phase 2 Controlled Study of SB206, a Topical Nitric Oxide-Releasing Drug for Extragenital Wart Treatment.

J Drugs Dermatol 2018 Oct;17(10):1100-1105

Background: Nitric oxide (NO), a free radical gas, is endogenously produced in human cells. In high concentration, NO neutralizes many disease-causing microbes. The topical investigational drug SB206 releases NO and has the potential to treat skin diseases caused by viruses. Read More

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October 2018
4 Reads

[HPV infection in women : Diagnostics, treatment and the relevance of vaccination].

Urologe A 2018 Dec;57(12):1445-1451

Frauenklinik der Technischen Universität München, Klinikum rechts der Isar, Ismaninger Str. 22, 81765, München, Deutschland.

Background: Benign, premalignant and malignant changes in the anogenital region, as in the oropharynx are often affected by a persistent HPV infection. Since a causal therapy isn't possible, the focus is on early diagnosis of dysplasia. Better knowledge of the human papilloma virus led to the development of the HPV vaccine and now primary prevention of cancer is possible. Read More

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December 2018
2 Reads

Extragenital condyloma acuminatum in the left axillary vault.

JAAD Case Rep 2018 Oct 11;4(9):947-949. Epub 2018 Oct 11.

Division of Dermatology, Washington University School of Medicine, St Louis, Missouri.

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October 2018
1 Read

Case of giant vulvar condyloma acuminata successfully treated with imiquimod 3.75% cream: A case report.

SAGE Open Med Case Rep 2018 10;6:2050313X18802143. Epub 2018 Oct 10.

Division of Dermatology, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, AB, Canada.

Condyloma acuminata, also known as anogenital warts, represent a cutaneous infection caused by sexual transmission of the human papilloma virus. We present a case of overwhelming condyloma acuminata that was treated successfully without surgery using only topical imiquimod 3.75% cream. Read More

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October 2018
5 Reads

Therapeutic effect of photodynamic therapy combined with imiquimod in the treatment of anal condyloma acuminatum and its effect on immune function.

Exp Ther Med 2018 Nov 3;16(5):3909-3912. Epub 2018 Sep 3.

Department of Dermatology, Liaocheng People's Hospital, Liaocheng, Shandong 252000, P.R. China.

Therapeutic effect of photodynamic therapy combined with imiquimod in the treatment of anal condyloma acuminatum (CA) was investigated to explore its effect on immune function. A total of 104 patients with anal CA were randomly divided into two groups: Patients in the study group were treated with photodynamic therapy combined with imiquimod, and ii) patients in the control group were treated with recombinant human interferon α-2b cream. Clinical efficacy and immune function related indicators were compared between the two groups. Read More

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November 2018
1 Read

Treatment of giant condyloma acuminatum of the anus. State of the art.

Ann Ital Chir 2018 ;89:291-294

Giant condyloma acuminatum (GCA) is a rare cauliflower-like lesion, also known as Buschke-L ewenstein tumor (BLT). Although characterized by benign histological features, the local behavior of GCA is extremely aggressive, showing progressive infiltration of the surrounding structures leading to tissue destruction by compression. As the correlation between HPV and GCA development grew stronger, the majority of the Authors came to the conclusion that HPV can not only cause CA but, associated with particular risk factors, it can lead to much more serious conditions such as BLT. Read More

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January 2018
2 Reads

Condyloma Acuminata of the Urethra in a Male Renal Transplant Recipient: A Case Report.

Transplant Proc 2018 Oct 20;50(8):2553-2557. Epub 2018 Mar 20.

Department of Urology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan; Department of Advanced Transplant and Regenerative Medicine, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.

Background: Condyloma acuminatum (CA) is a common sexually transmitted disease associated with human papilloma virus (HPV). CA occurring in the urethra is rare and has not been reported in male renal transplant recipients. In addition, despite immunosuppressive conditions and increased risk of HPV-related malignant neoplasms in transplant recipients, HPV testing in male transplant recipients has been uncommon. Read More

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October 2018
6 Reads

HPV 6-associated HSIL/Squamous Carcinoma in the Anogenital Tract.

Int J Gynecol Pathol 2018 Oct 11. Epub 2018 Oct 11.

Department of Pathology, Division of Women's and Perinatal Pathology, Brigham and Women's Hospital, Boston, Massachusetts (M.Z.L., Y.P.H., M.R.N., C.P.C.) Department of Pathology, Division of Cytopathology, University of Washington Health Sciences Center, Seattle, Washington (E.C.H.) Department of Pathology, Stanford University Medical Center, Palo Alto, California (B.E.H.).

Human papillomavirus (HPV) type 6 is historically classified as low-risk HPV type and associates with low-grade squamous intraepithelial lesions of the anogenital tract. Rare squamous carcinomas have been reported in association with these HPV types but the mechanism(s) behind this carcinogenic sequence have been unclear. We report 4 cases of low risk anogenital HPV infections-3 cervical (immature low-grade squamous intraepithelial lesion with metaplastic phenotype) and one anal (exophytic condyloma) lesion-that manifested with high-grade squamous intraepithelial lesion/squamous cell carcinoma. Read More

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October 2018
6 Reads

Ingenol mebutate induces a tumor cell-directed inflammatory response and antimicrobial peptides thereby promoting rapid tumor destruction and wound healing.

Eur J Med Res 2018 Sep 28;23(1):45. Epub 2018 Sep 28.

Department of Dermatology, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.

Background: Ingenol mebutat (IM)-gel is effective for the topical treatment of epithelial tumors, including actinic keratoses (AKs) or anogenital warts (AGW). AK patients treated with IM develop intensified inflammatory reactions on sights of prior clinical visible or palpable AKs as compared to the surrounding actinically damaged skin, suggesting the induction of a tumor cell-directed inflammation. AGW patients treated with IM develop even stronger inflammatory reactions with large erosions, suggesting a directed inflammatory response against HPV-infected keratinocytes. Read More

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September 2018
2 Reads

Photodynamic therapy as an alternative therapeutic option for pediatric condyloma acuminata: A case series.

Photodiagnosis Photodyn Ther 2018 12 20;24:179-181. Epub 2018 Sep 20.

Department of Dermatology and Venereology, Nanfang Hospital, Southern Medical University, Guangzhou, China. Electronic address:

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December 2018
1 Read

Loss of miR-143 and miR-145 in condyloma acuminatum promotes cellular proliferation and inhibits apoptosis by targeting NRAS.

R Soc Open Sci 2018 Aug 29;5(8):172376. Epub 2018 Aug 29.

Department of Dermatology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, People's Republic of China.

The expression profile of miRNAs and their function in condyloma acuminatum (CA) remains unknown. In this study, we aimed to detect the effects of miR-143 and miR-145, the most downregulated in CA samples using high-throughput sequencing, on cell proliferation and apoptosis, to determine a novel therapeutic target for CA recurrence. RT-qPCR was used to validate the lower expression of miR-143 and miR-145 in a larger size of CA samples, and the expression of NRAS in CA samples was significantly higher than self-controls as determined by western blotting assay. Read More

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August 2018
1 Read

5-aminolevulinic acid photodynamic therapy for anal canal condyloma acuminatum: A series of 19 cases and literature review.

Photodiagnosis Photodyn Ther 2018 Sep 6;23:230-234. Epub 2018 Jul 6.

Department of Dermatology and Venereology, Nanfang hospital, Southern Medical University, Guangzhou, 510515, China. Electronic address:

Background: Anal canal condyloma acuminata are common, sexually transmitted lesions, most often caused by the human papillomavirus. The relatively high recurrence rate of anal canal condyloma acuminata can be attributed to the unsuccessful elimination of viruses in areas of subclinical and latent infection. This study aimed to observe and evaluate the effectiveness of 5-aminolevulinic acid-photodynamic therapy combined with monitoring of human papillomavirus load changes in patients with anal canal condyloma acuminata. Read More

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September 2018
1 Read
2.010 Impact Factor

Verruciform and Condyloma-like Squamous Proliferations in the Anogenital Region.

Authors:
May P Chan

Arch Pathol Lab Med 2018 Sep 11. Epub 2018 Sep 11.

From the Department of Pathology, University of Michigan Health System, Ann Arbor.

Context: - Histologic distinction between condyloma acuminatum and various benign and malignant condyloma-like lesions in the anogenital area poses a common diagnostic challenge to pathologists across subspecialties.

Objective: - To review the overlapping and distinguishing features of condyloma acuminatum and its mimics, and to clarify confusing terminology and diagnostic criteria for problematic entities.

Data Sources: - A review of the literature on condyloma acuminatum (ordinary and giant types), verrucous carcinoma, warty/warty-basaloid high-grade squamous intraepithelial lesion and squamous cell carcinoma, papillary squamous cell carcinoma, bowenoid papulosis, verruca vulgaris, epidermolytic acanthoma, and verruciform xanthoma was performed. Read More

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September 2018
6 Reads

Eliminating parental consent for adolescents receiving human papillomavirus vaccination.

R I Med J (2013) 2018 Sep 4;101(7):12-14. Epub 2018 Sep 4.

pathologist at Women & Infants Hospital of Rhode Island and Assistant Professor of Pathology and Laboratory Medicine at the Warren Alpert Medical School of Brown University.

Human papillomavirus (HPV) is a sexually transmitted infection (STI) causing nearly all cases of cervical carcinoma and genital condyloma worldwide. While HPV vaccination rates are higher in Rhode Island compared to other states, still 27% of female adolescents are not fully vaccinated. The requirement for parental consent for vaccination administration poses a barrier to HPV vaccine uptake and hinders adolescent autonomy. Read More

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September 2018
2 Reads

Verrucous Carcinoma Arising in Association With Giant Condyloma.

Int J Surg Pathol 2018 Sep 5:1066896918796647. Epub 2018 Sep 5.

1 Brown University, Providence, RI, USA.

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September 2018
2 Reads

Successful treatment of giant condyloma in a pediatric heart transplant recipient with topical cidofovir.

Transpl Infect Dis 2018 Dec 28;20(6):e12989. Epub 2018 Sep 28.

Department of Pediatrics, Division of Infectious Diseases, University of Texas Southwestern Medical Center, Dallas, Texas.

We report a case of giant condyloma that developed in a pediatric heart transplant recipient. This infection progressed for several months despite reduction in immunosuppression, topical treatment, and oral cimetidine therapy. Complete resolution was observed following 7 months of topical cidofovir, without evidence of systemic toxicity or rejection. Read More

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December 2018
11 Reads

Oral manifestations of human papillomavirus infections.

Authors:
Stina Syrjänen

Eur J Oral Sci 2018 Oct;126 Suppl 1:49-66

Department of Oral Pathology and Oral Radiology, Institute of Dentistry, Faculty of Medicine, University of Turku, Turku, Finland.

Papillomaviruses are one of the oldest viruses known, dating back 330 million years. During this long evolution, human papillomaviruses (HPV) have developed into hijackers of human cellular and immune systems in which they replicate and remain silent. Systematic studies on oral HPV infections and their outcomes are still scarce. Read More

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October 2018
1 Read

Multimodality Imaging Review of Anorectal and Perirectal Diseases With Histological, Endoscopic, and Operative Correlation, Part I: Anatomy and Neoplasms.

Curr Probl Diagn Radiol 2018 Jul 29. Epub 2018 Jul 29.

Department of Radiology, Louisiana State University Health Shreveport, Shreveport, LA.

A broad spectrum of pathology affects the rectum, anus, and perineum and understanding of its relevant anatomy is important in accurate reporting, particularly in rectal cancer. In this pictorial essay, correlative imaging, endoscopic, pathologic, and operative images are presented to illustrate normal anorectal anatomy and neoplastic conditions that affect the anus and rectum. A particular case-based focus is given to rectal adenocarcinoma with pelvic MR and surgical histopathology. Read More

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July 2018
9 Reads

The role of regulatory T cells in pathogenesis and therapy of human papillomavirus-related diseases, especially in cancer.

Infect Genet Evol 2018 Nov 29;65:406-413. Epub 2018 Aug 29.

Department of Dermatology and Venereology, Nanfang hospital, Southern Medical University, Guangzhou, 510515, China. Electronic address:

Human papillomavirus (HPV) is the most common sexually transmitted agent in the world. It can cause condyloma acuminatum, anogenital malignancies, and head and neck cancers. The host immune responses to HPV involve multiple cell types that have regulatory functions, and HPV-mediated changes to regulatory T cells (Tregs) in both the local lesion tissues and the circulatory system of patients have received considerable attention. Read More

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November 2018
6 Reads

[Clinicopathological features and management of penile verrucous carcinoma].

Zhonghua Nan Ke Xue 2018 Janurary;24(1):62-66

Department of Urology, Henan Provincial People's Hospital / People's Hospital of Zhengzhou University, Zhengzhou, Henan 450003, China.

Objective: To explore the clinicopathological characteristics, diagnosis and treatment of penile verrucous carcinoma (VC).

Methods: We retrospectively analyzed the clinical data about 18 penile VC patients at the mean age of 52 (35-66) years. The tumors were cauliflower-like, measuring 2. Read More

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November 2018
10 Reads

Treatment of intraurethral condylomata acuminata with surgery and cidofovir instillations in two immunocompromised patients and review of the literature.

Antiviral Res 2018 Oct 25;158:238-243. Epub 2018 Aug 25.

Department of Urology, University Hospitals Leuven, Leuven, Belgium.

Condylomata acuminata (CA) or anogenital warts are benign proliferative lesions caused by low-risk human papillomaviruses (HPV). Treating CA can be very frustrating for patients and clinicians due to the high recurrence rates. Immunosuppression is associated with larger size of CA that are more frequently resistant to treatment. Read More

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October 2018
9 Reads

Condylomata acuminata (anogenital warts) contain accumulations of HIV-1 target cells that may provide portals for HIV transmission.

J Infect Dis 2018 Aug 18. Epub 2018 Aug 18.

Department of Obstetrics and Gynecology, Boston University School of Medicine, Boston, MA.

Background: Condylomata acuminata [anogenital warts (AGW)] are prevalent in HIV-infected individuals and sexually active populations at risk for HIV acquisition, and have been associated with HIV transmission. We compared AGW to control tissue for abundance, types and location of HIV-target cells, and for susceptibility to HIV infection in vitro, to provide biological evidence that AGW facilitate HIV transmission.

Methods: We used immunohistology to identify HIV-target cells in AGW and control skin. Read More

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August 2018
10 Reads

Human Papillomavirus-Associated Invasive Condylomas in a Man with Immunosuppressive Comorbidities.

Urol Int 2018 Aug 21:1-5. Epub 2018 Aug 21.

Department of Urology and Pediatric Urology, Saarland University, Homburg, Germany.

Human papilloma virus (HPV) infections are one of the most common sexually transmitted diseases. We present the case of a 77-year-old Caucasian male with enormous genital warts of the penis, scrotum, groins and anus. Lesions were excised by electrosurgery. Read More

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August 2018
15 Reads

Giant condyloma acuminatum of the vulva: Successful management with imiquimod.

JAAD Case Rep 2018 Aug 15;4(7):692-694. Epub 2018 Aug 15.

Department of Obstetrics and Gynecology, Angers University Hospital, Angers, France.

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August 2018
13 Reads

Anti-Condyloma acuminata mechanism of microRNAs-375 modulates HPV in cervical cancer cells via the UBE3A and IGF-1R pathway.

Oncol Lett 2018 Sep 18;16(3):3241-3247. Epub 2018 Jun 18.

Department of Dermatology, Tianjin Union Medical Center, Tianjin 300121, P.R. China.

The present study aimed to identify the probable anti-Condyloma acuminata (CA) mechanism of microRNA-375 (miRNA-375) in human papillomavirus (HPV). Firstly, the overexpression of miRNA-375 significantly suppressed cell proliferation, increased lactate dehydrogenase activity and induced apoptosis in HPV-18(+) cervical cancer cells. The overexpression of miRNA-375 significantly increased caspase-3 and caspase-9 activities, induced B-cell lymphoma 2 (Bcl-2)/Bcl-2-associated X protein, tumor protein 53 and cyclin-dependent kinase inhibitor 1 protein expression and suppressed cyclin D1 and survivin protein expression in HPV-18(+) cervical cancer cells. Read More

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September 2018
4 Reads

Cantharidin is Superior to Trichloroacetic Acid for the Treatment of Non-mucosal Genital Warts: A Pilot Randomized Controlled Trial.

Clin Exp Obstet Gynecol 2018 ;45(3):383-386

Department of Obstetrics and Gynecology, University of New Mexico, Albuquerque, NM.

Condyloma Acuminatum is a sexually transmitted viral disease caused by the human papilloma virus (HPV). It is the most common viral sexually transmitted disease. In this randomized controlled trial, cantharidin was found to be more effective and better tolerated than trichloroacetic acid for the treatment of these lesions. Read More

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August 2018
9 Reads

Effectiveness of physically ablative and pharmacological treatments for anal condyloma in HIV-infected men.

PLoS One 2018 1;13(8):e0199033. Epub 2018 Aug 1.

Department of Surgery, University Hospital Germans Trias i Pujol, Badalona, Catalonia, Spain.

Background: There is limited information on the effectiveness of available treatments for anal condyloma acuminata in HIV-1-infected men.

Aim: To provide data on the effectiveness of electrosurgical excision, infrared coagulation and pharmacological (imiquimod) treatments for anal condyloma acuminata (peri-anal and/or intra-anal) in HIV-1-infected men based on authors' practice.

Methods: Single-center, retrospective descriptive analysis of HIV-1-infected men, 18 years or older treated for anal condyloma acuminata. Read More

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August 2018
4 Reads

Successful treatment of penile condyloma acuminata accompanied with lichen planus with photodynamic therapy.

Photodiagnosis Photodyn Ther 2018 Dec 29;24:142-144. Epub 2018 Jul 29.

Department of Dermatology, Huadong Hospital, Fudan University, Shanghai 200040, PR China. Electronic address:

Condyloma acuminata and lichen planus are different cutaneous diseases with disparate etiologies. Simultaneous appearance of two diseases in the same area is rare. This report aims to share the clinical and pathological features of a rare case; introduce an effective and safe therapy of it so as to broaden the therapeutic spectrum of Photodynamic Therapy (PDT) indications. Read More

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December 2018
2 Reads

Imiquimod-induced hypopigmentation following treatment of periungual verruca vulgaris.

Cutis 2018 Jun;101(6):466-468

Bay Pines VA Healthcare System, St. Petersburg, Florida, USA.

Imiquimod is a topical immunomodulating medication approved by the US Food and Drug Administration for the treatment of condyloma acuminata, actinic keratoses (AKs), and superficial basal cell carcinoma (BCC). Imiquimod commonly is used off label for its antiviral and antitumoral effects. We present a case of a 51-year-old man with vitiligolike depigmentation following treatment of periungual verruca vulgaris with imiquimod therapy. Read More

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June 2018
1 Read

MicroRNA-551b expression profile in low and high-grade cervical intraepithelial neoplasia.

Eur Rev Med Pharmacol Sci 2018 Jul;22(14):4448-4457

Department of Surgical and Medical Sciences and Translational Medicine, Sapienza University of Rome, Sant'Andrea Hospital, Rome, Italy.

Objective: To evaluate the expression of microRNA (miR)-551b in patients with low and high grade cervical intraepithelial neoplasia (CIN) and to find an association with high-risk Human Papillomavirus (HR-HPV) infection-related prognostic biomarkers.

Patients And Methods: The expression level of miR-551b was determined in 50 paraffin-embedded cervical specimens (10 normal squamous epithelium, 18 condylomas, 8 CIN1, and 14 CIN2-3) using quantitative Real-time polymerase chain reaction (qRT-PCR). χ2-test compared miR-551b expression in different diagnosis groups. Read More

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July 2018
2 Reads

Treatment of latent or subclinical Genital HPV Infection with 5-aminolevulinic acid-based photodynamic therapy.

Photodiagnosis Photodyn Ther 2018 Sep 23;23:362-364. Epub 2018 Jul 23.

Department of Dermatology and Venereology, Nanfang hospital, Southern Medical University, Guangzhou 510515, China. Electronic address:

Background: Genital HPV infections are widely prevalent. HPV can persist and be transmitted to partners even after warts are gone. The HPV genotype and viral load assay can reveal whether infections are persistent or latent, and it can serve as a predictor of infection clearance. Read More

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September 2018
2 Reads

Development of a human papillomavirus type 6/11 vaccine candidate for the prevention of condyloma acuminatum.

Vaccine 2018 08 2;36(32 Pt B):4927-4934. Epub 2018 Jul 2.

Departments of Molecular Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, China. Electronic address:

Condyloma acuminatum (CA) represents a significant human papillomavirus (HPV) disease burden worldwide, resulting in substantial healthcare costs and loss of life quality in both genders. To address this problem, we tried to develop a bivalent HPV6/11 virus-like particle (VLP) vaccine targeting CA. HPV6/11 VLPs were generated in Hansenula polymorpha, and a disassembly and reassembly (D/R) treatment was further conducted to improve the stability and monodispersity of the VLPs. Read More

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August 2018
8 Reads

[Treatment of HPV-associated Anal Lesions in HIV-positive Patients - Comparison of Surgical Treatment and Topical Therapy with Imiquimod].

Zentralbl Chir 2018 Jul 3. Epub 2018 Jul 3.

Klinik und Poliklinik für Allgemein-, Viszeral-, Thorax- und Gefäßchirurgie, Universitätsklinikum Bonn, Deutschland.

Objectives: In HIV-patients, routine proctological assessment is warranted due to the high incidence of human papilloma virus (HPV) infection-related anogenital lesions, such as Condylomata acuminata (C. ac.), anal intraepithelial dysplasia (AIN) and anal cancer. Read More

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July 2018
10 Reads

Anogenital warts in children: Analysis of a cohort of 34 prepubertal children.

Pediatr Dermatol 2018 Sep 1;35(5):e325-e327. Epub 2018 Jul 1.

Department of Dermatovenereology, Centro Hospitalar de São João, EPE, Porto, Portugal.

Anogenital warts are caused by infection with the human papillomavirus. We reviewed the clinical data of 34 children younger than 13 with anogenital warts referred to the department of dermatovenereology of a tertiary care hospital. Suspicion of sexual abuse was raised in 11 (32. Read More

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September 2018
11 Reads

[Pigmented extramammary Paget's disease accompanied with condyloma acuminatum: a case report].

Beijing Da Xue Xue Bao Yi Xue Ban 2018 Jun;50(3):572-575

Department of Dermatology, Peking University People's Hospital, Beijing 100044, China.

Pigmented extramammary Paget's disease (PEMPD) is an uncommon intraepithelial adenocarcinoma and a rare variant of Paget's disease, characterized as a superficial pigmented scaly macule clinically and an increased number of melanocytes scattered between the Paget's cells histologically. So it may be confused clinically and histologically with melanocytic tumors, dermatitis and other dermatoses. Different therapeutic attitudes are required in this case of adenocarcinoma in situ as opposed to melanoma and dermatitis. Read More

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June 2018
11 Reads

Everolimus and papillomavirus lesions in female renal transplant recipient: A case report.

Gynecol Oncol Rep 2018 Aug 4;25:63-64. Epub 2018 Jun 4.

Department of Cardiovascular Surgery, University Hospital Center Osijek, Faculty of Medicine, University of Osijek, Huttlerova 4, 31000 Osijek, Croatia.

We describe the case of a transplanted patient with high-risk HPV infection that manifested as multiple genital condylomas and abnormal Papanicolaou (Pap) smear. Her immunosuppressants were corticosteroids, cyclosporine, and azathioprine. Since gynecologic treatments to eradicate condylomas were completely unsuccessful, cyclosporine was replaced by everolimus. Read More

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August 2018
6 Reads

Underwater endoscopic mucosal resection of anal condyloma.

VideoGIE 2018 Apr 14;3(4):123-124. Epub 2018 Feb 14.

Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, California, USA.

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April 2018
1 Read

A comparative study of two techniques in the treatment of condyloma acuminata.

Ann Ital Chir 2018 Jun 14;7. Epub 2018 Jun 14.

Objectives: Condyloma acuminata (CA) is mainly caused by human papillomavirus (HPV) types 6 and 11. Clinicians use many different methods to treat analcondyloma acuminate ( CA). In this study, we aimed to compare electrocautery ablation (ECA) and argon plasma coagulation (APC) techniques in terms of postoperative bleeding, pain, scar development, loss of sexual sensation, and recurrence rates. Read More

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June 2018
26 Reads

DNAJA4 deficiency enhances NF-kappa B-related growth arrest induced by hyperthermia in human keratinocytes.

J Dermatol Sci 2018 Sep 23;91(3):256-267. Epub 2018 May 23.

China Medical University, Shenyang, 110001, China; Department of Dermatology, No.1 Hospital of China Medical University, China; Key Laboratory of Immunodermatology, Ministry of Health and Ministry of Education, Shenyang, 110001, China. Electronic address:

Background: Hyperthermia is an effective treatment against cancer and human papillomavirus (HPV) infection. Previous studies have shown that heat shock proteins are crucial to the action of hyperthermia.

Objectives: To examine the effects of hyperthermia in combination with DNAJA4-deficiency on human keratinocytes and Condyloma acumunatum (CA) tissues. Read More

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September 2018
5 Reads

Preemptive Analgesia Decreases Pain Following Anorectal Surgery: A Prospective, Randomized, Double-Blinded, Placebo-Controlled Trial.

Dis Colon Rectum 2018 Jul;61(7):824-829

Department of Surgery, University of Vermont Medical Center, Burlington, Vermont.

Background: Postoperative pain is a frequent cause for delayed discharge following outpatient procedures, including anorectal surgery. Both central and peripheral pain receptor sensitization are thought to contribute to postoperative pain. Blocking these receptors and preempting sensitization prevents hyperalgesia leading to lower pain medication requirements. Read More

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July 2018
3 Reads

Perianal condyloma acuminatum-like plaque.

Cutis 2018 Apr;101(4):248;255;256;259

Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina, Charleston, USA.

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April 2018
3 Reads

The Impact of Varying Numbers of Quadrivalent Human Papillomavirus Vaccine Doses on Anogenital Warts in the United States: A Database Study.

J Low Genit Tract Dis 2018 Jul;22(3):189-194

Department of Obstetrics & Gynecology, The University of Texas Medical Branch at Galveston, TX.

Objective: The aim of the study was to investigate the effects of 3 or less quadrivalent human papillomavirus (HPV) vaccine doses on anogenital warts in both males and females in the United States.

Materials And Methods: We conducted a retrospective database study that included males and females aged 9 to 26 years who received varying numbers of vaccine doses between 2006 and 2015. The primary outcome was the incidence of anogenital warts starting 3 months after the last dose of the HPV vaccine. Read More

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July 2018
7 Reads

Genital Wart and Human Papillomavirus Prevalence in Men in the United States From Penile Swabs: Results From National Health and Nutrition Examination Surveys.

Sex Transm Dis 2018 Jun;45(6):412-416

From the Department of Urology, SUNY Upstate Medical University, Syracuse, NY.

Introduction: Human papillomavirus (HPV) is a common sexually transmitted infection in the United States that can lead to both malignant (high-risk) and benign (low-risk) findings. These low-risk findings include both genital condyloma, anal warts, and adult or juvenile papillomatosis, which are directly attributable to subtypes HPV 6 and HPV 11. We aim to estimate the prevalence of genital wart infections in men in the US population using a nationwide sample. Read More

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June 2018
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