5,717 results match your criteria Condyloma Acuminata


Comparison between anal cytology, high-resolution anoscopy and HPV DNA genotyping by polymerase chain reaction in the post-treatment follow-up of condylomata acuminata.

Rev Col Bras Cir 2020 3;47:e20202543. Epub 2020 Jul 3.

Instituto de Infectologia Emilio Ribas, São Paulo, SP, Brasil.

Aim: to evaluate the presence of subclinical HPV-induced anal lesions with anal cytology, High-Resolution Anoscopy (HRA) and HPV genotyping by polymerase chain reaction (PCR) in the follow-up of treated condylomata acuminata (CA).

Methods: seventy-nine male patients were included. One month after anal CA eradication, the patients underwent brush samples collection for anal cytology and PCR, and HRA with biopsy of acetowhite lesions. Read More

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http://dx.doi.org/10.1590/0100-6991e-20202543DOI Listing

Modified photodynamic therapy to minimize pain in the treatment of condylomata acuminata: a prospective, randomized, self-controlled study.

Photodiagnosis Photodyn Ther 2020 Jul 4:101915. Epub 2020 Jul 4.

Institute of Photomedicine, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai, China. Electronic address:

Background: Pain is a major concern associated with conventional photodynamic therapy (C-PDT).

Objective: To evaluate the efficacy, pain and safety of modified photodynamic therapy(M-PDT) for the treatment of condylomata acuminata.

Methods: A prospective, randomized, self-controlled study was conducted. Read More

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http://dx.doi.org/10.1016/j.pdpdt.2020.101915DOI Listing

Primary Urothelium Carcinoma of the Distal Urethra in a Male: Case Report and Literature Review.

Onco Targets Ther 2020 24;13:6011-6015. Epub 2020 Jun 24.

Department of Urology, Nan Fang Hospital, Southern Medical University, Guangzhou City, Guangdong Province 510515, People's Republic of China.

Male primary urethral urothelium carcinoma is a rare clinical case. Here, we detail a case of a 58-year-old man with primary urothelium carcinoma of the distal urethra treated in our hospital. The patient with a neoplasm inside the external urethral orifice for 2 years, which was previously diagnosed as condyloma acuminata, had received photodynamic therapy for 3 times, with initial symptoms of urinary stream bifurcation and dysuria. Read More

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http://dx.doi.org/10.2147/OTT.S252822DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322166PMC

Grand Rounds: Presentation of a Large and Debilitating Fungating Anogenital Lesion.

Urology 2020 Jun 9. Epub 2020 Jun 9.

The Brady Urological Institute, Johns Hopkins School of Medicine, Baltimore, MD. Electronic address:

Case Report: A 65-year-old Caucasian man presented with a debilitating anogenital lesion.

Differential Diagnosis: The differential diagnosis of anogenital lesions includes infectious (syphilis, herpes simplex virus), noninfectious (hidradenitis suppuritiva, lymphedema), benign (condyloma acuminata), and malignant pathologies (squamous cell carcinoma, Kaposi sarcoma).

Diagnostic Assessment, Management, And Outcome: Biopsy of an anogenital lesion will determine any oncologic potential. Read More

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http://dx.doi.org/10.1016/j.urology.2020.05.057DOI Listing

Nonavalent human papillomavirus vaccination as alternative treatment for genital warts.

Dermatol Ther 2020 Jun 4:e13771. Epub 2020 Jun 4.

Department of Dermatology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

Genital warts caused by the human papillomavirus (HPV) are the most common sexually transmitted disease and have a negative impact on quality of life. Of the more than 200 different types of HPV, low-risk types 6 and 11 are mainly responsible for the development of condyloma acuminata. Despite a large arsenal of local therapies such as numerous topical agents, CO laser ablation, and surgical removal, genital warts tend to be recalcitrant. Read More

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http://dx.doi.org/10.1111/dth.13771DOI Listing

Successful management of giant condyloma acuminatum of vulva with combination of surgical and photodynamic therapy: report of two cases.

Photodiagnosis Photodyn Ther 2020 May 29:101847. Epub 2020 May 29.

Department of Dermatology, The Second Xiangya Hospital of Central South University, Changsha 410011, China. Electronic address:

Patients with condylomata acuminata of the vulva usually have an increased difficulty for treatments and a higher risk of disease recurrence. Treatments for this disease varies, including surgical excision, cryotherapy, electrocautery, CO2 laser therapy, topical therapy, and photodynamic therapy (PDT), but none of these provides a satisfactory outcome in most refractory cases, especially for giant condyloma acuminatum (GCA). We reported two cases of GCA successfully cured with surgical removal, electrocautery and photodynamic therapy. Read More

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http://dx.doi.org/10.1016/j.pdpdt.2020.101847DOI Listing

Successful topical treatment of anal giant condylomata acuminata in an infant.

Dermatol Ther 2020 May 19:e13624. Epub 2020 May 19.

Dermatology Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.

Anogenital condylomata acuminata are induced by human papillomavirus (HPV) and they rarely manifest in immunocompetent children. Therapeutic options depend on patient's age and general conditions and extension of the lesions. However, management is still a challenge and recurrences are frequent. Read More

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http://dx.doi.org/10.1111/dth.13624DOI Listing

"Verrucous vulva": Meeting therapeutic challenges in massive condyloma acuminata with intralesional immunotherapy.

Authors:
Saurabh Singh

Indian J Dermatol Venereol Leprol 2020 Jul-Aug;86(4):456-458

Associate Professor, Department of Dermatology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.

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http://dx.doi.org/10.4103/ijdvl.IJDVL_535_19DOI Listing

Human papillomavirus-negative epithelial proliferations resembling condylomata acuminata in a patient receiving vemurafenib for Stage IV melanoma.

J Cancer Res Ther 2020 Jan-Mar;16(1):170-172

Department of Dermatology, Netherlands Cancer Institute, Amsterdam, Netherlands.

With the discovery of v-Raf murine sarcoma viral oncogene homolog B (BRAF) inhibitors, new treatment possibilities arose against metastatic melanoma. A frequent adverse effect of BRAF inhibitor therapy is the induction of epithelial proliferations such as cutaneous squamous cell carcinoma and verrucous papilloma. Here, we describe a case in which a patient developed extensive anal epithelial proliferations resembling condylomata acuminata, after starting vemurafenib treatment. Read More

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http://dx.doi.org/10.4103/jcrt.JCRT_317_17DOI Listing

Burden of HPV related anogenital diseases in young women in Germany - an analysis of German statutory health insurance claims data from 2012 to 2017.

BMC Infect Dis 2020 Apr 22;20(1):297. Epub 2020 Apr 22.

Department of Obstetrics and Gynecology, University Hospital of Duesseldorf, Duesseldorf, Germany.

Background: Most individuals are infected with human papillomavirus (HPV) at least once in their lifetime. Infections with low-risk types can cause genital warts, whereas high-risk types can cause malignant tumors. The aim of this study was to determine the burden of anogenital diseases potentially related to HPV in young women based on German statutory health insurance claims data. Read More

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http://dx.doi.org/10.1186/s12879-020-05002-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7178589PMC

ALA-PDT combined with cystoscopy: a method to eliminate refractory HPV infection in a patient with condyloma acuminata.

Photodiagnosis Photodyn Ther 2020 Apr 7:101763. Epub 2020 Apr 7.

Department of Dermatology and Venereology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China. Electronic address:

Background: Condyloma acuminata is a common sexually transmitted disease whose recurrence is caused by an underlying chronic human papillomavirus (HPV) infection. 5-Aminolaevulinic acid-mediated photodynamic therapy (ALA-PDT) has become an effective method to treat condyloma acuminata. Urinary tract condyloma acuminata are rare, but warts in the bladder could be detected by cystoscopy. Read More

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http://dx.doi.org/10.1016/j.pdpdt.2020.101763DOI Listing

Assessing Gammapapillomavirus infections of mucosal epithelia with two broad-spectrum PCR protocols.

BMC Infect Dis 2020 Apr 7;20(1):274. Epub 2020 Apr 7.

Grupo Virología Humana, Instituto de Biología Molecular y Celular de Rosario (CONICET), Suipacha 590, 2000, Rosario, Argentina.

Background: Human papillomaviruses (HPVs) have been divided into mucosal and cutaneous types according to their primary epithelial tissue tropism. However, recent studies showed the presence of several cutaneous types in mucosal lesions and healthy mucosa from different anatomical sites.

Methods: Here, the HPV prevalence and type-specific distribution were assessed in a variety of mucosal samples from 435 individuals using a combination of two established broad-spectrum primer systems: Gamma-PV PCR and CUT PCR. Read More

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http://dx.doi.org/10.1186/s12879-020-4893-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140492PMC

Erythema nodosum induced by oral isotretinoin in a patient with condylomata acuminata.

Dermatol Online J 2020 Feb 15;26(2). Epub 2020 Feb 15.

Department of Dermatology, School of Medicine, University of Patras.

Erythema nodosum (EN) is a form of septal panniculitis, which is believed to represent a delayed hypersensitivity reaction activated by infectious agents, drugs, granulomatous and autoimmune diseases, pregnancy, and malignancies. There are only four reported cases of EN during oral isotretinoin therapy to our knowledge, all of them occurring in patients with severe acne. Since acne itself can trigger EN, the question as to whether there is indeed a causative relationship between isotretinoin and EN in the reported cases remains to be elucidated. Read More

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February 2020

Prevalence of Cervico-vaginal High-risk HPV Types and Other Sexually Transmitted Pathogens in Anogenital Warts Patients.

Anticancer Res 2020 Apr;40(4):2219-2223

1 Department of Dermatology and Venereology, National and Kapodistrian University of Athens, "Andreas Sygros" Hospital for Skin and Venereal Diseases, Athens, Greece.

Aim: To investigate the prevalence of cervico-vaginal co-infection with high-risk (HR) HPV types and other sexually transmitted pathogens (STPs) in women with anogenital warts (AGWs).

Patients And Methods: In this cross-sectional study, cervico-vaginal smears of women with AGWs were examined with real-time polymerase chain reaction for the presence of HR-HPV types and common STPs. Women with recent cervical HPV infection and general population were used for comparisons. Read More

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http://dx.doi.org/10.21873/anticanres.14183DOI Listing

[Correlation of human papillomavirus (HPV) and HPV vaccines with male reproductive health].

Zhonghua Nan Ke Xue 2019 Aug;25(8):749-753

Department of Urology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266003, China.

HPV is a very common virus worldwide spread by direct contact and involved in male reproductive health-related diseases such as infertility, condyloma acuminatum, and penile cancer. The development of HPV vaccines has contributed to the effective prevention of various subtypes of HPV and protection of males from HPV infection, especially the partners of HPV-positive females, the men who have sex with men, and those with a psychological fear of HPV infection. Therefore, HPV vaccines play an important role in the protection of males. Read More

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HPV-associated anal lesions in HIV+ patients: long-term results regarding quality of life.

Int J Colorectal Dis 2020 Jun 26;35(6):1103-1110. Epub 2020 Mar 26.

Department of Surgery, University Hospital of Bonn, Sigmund-Freud-Str. 25, Bonn, Germany.

Purpose: HIV infection and concomitant HPV-associated anal lesions may significantly impact on patients' quality of life (QoL), as they are predicted to have negative effects on health, psyche, and sexuality.

Material And Methods: Fifty-two HIV+ patients with HPV-associated anal lesions were enrolled in a survey approach after undergoing routine proctologic assessment and therapy for HPV-associated anal lesions if indicated over a time span of 11 years (11/2004-11/2015). Therapy consisted of surgical ablation and topic treatment. Read More

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http://dx.doi.org/10.1007/s00384-020-03567-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245587PMC

Condylomata acuminata: A retrospective analysis on clinical characteristics and treatment options.

Heliyon 2020 Mar 11;6(3):e03547. Epub 2020 Mar 11.

Department of Dermatology and Allergy, University Hospital of Munich (LMU), Munich, Germany.

Background: Anogenital HPV is the most frequent sexually transmitted disease (STD) worldwide. There is no obligation to officially register HPV infections in Germany and thus the epidemiology of condylomata acuminata (CA) is not well characterized.

Objectives: To provide a better understanding of the epidemiology of CA and outline the treatment options that are available to patients with this disease. Read More

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http://dx.doi.org/10.1016/j.heliyon.2020.e03547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068618PMC

Pan-urethral condylomata acuminata - A primary treatment recommendation based on our experience.

Urol Case Rep 2020 Jul 29;31:101149. Epub 2020 Feb 29.

Department of Urology, Austin Health, Heidelberg, VIC, Australia.

We present a case of a 28 year old man presenting with obstructive urinary tract symptoms and cystoscopic findings of pan-urethral, occlusive condylomata acuminata (urethral genital warts). We describe the in rooms administration process of 5-fluorouracil over an 8 week period with follow up cystoscopy results. Urine flow rates improved early in the treatment course from a maximum flow of 7ml/s to 19ml/s and a post void residual improvement from 311ml to 160ml. Read More

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http://dx.doi.org/10.1016/j.eucr.2020.101149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7056647PMC

Aspects of Langerhans cells and TNF-α in the cutaneous immunity of anogenital warts.

An Bras Dermatol 2020 Mar - Apr;95(2):144-149. Epub 2020 Feb 12.

Pathology Laboratory, Santa Casa de Misericórdia de São Paulo, Vila Buarque, SP, Brazil.

Background: Anogenital warts are the leading sexually transmitted infection in patients seeking care at specialized clinics. They may display a vast array of forms, according to the interaction of the virus with the host's immunity. Cellular immunity is the epithelium's main form of defense against the virus, involving an active participation of the Langerhans cells and pro-inflammatory cytokines such as TNF-α. Read More

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http://dx.doi.org/10.1016/j.abd.2019.06.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175043PMC

Cure of condyloma acuminata covering the glans penis using aminolevulinic acid/photodynamic therapy.

Photodiagnosis Photodyn Ther 2020 Jun 26;30:101658. Epub 2020 Feb 26.

The First Affiliated Hospital of Zhengzhou University, China.

Condyloma acuminata are a type of verrucous hyperplasia in the genital and perianal areas caused by human papilloma virus (HPV) infection. Traditional treatment methods for condyloma acuminata, such as topical medications, carbon dioxide (CO) laser, cryotherapy, and surgical excision, can be effective at removing warts, however, they do not eliminate subclinical and latent HPV infection, resulting in a high recurrence rate and even leaving trauma and scars. We report a case of condyloma acuminata covering the glans penis, considering our patient had a singular, large lesion, thus, to reduce the risk of recurrence and minimize the trauma caused by treatment, we chose ALA/photodynamic therapy (ALA-PDT). Read More

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http://dx.doi.org/10.1016/j.pdpdt.2020.101658DOI Listing

Advanced application of holmium: YAG laser combined ALA-PDT for the treatment of refractory condylomata acuminata in anal canal.

Photodiagnosis Photodyn Ther 2020 Jun 25;30:101696. Epub 2020 Feb 25.

Institute of Photomedicine, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai, 200443, China. Electronic address:

Background: Anal canal condylomata acuminata is a disease caused by the human papilloma virus. Conventional cauterizing laser treatment cannot achieve a satisfactory result owing to a high recurrence rate, and the application of 5-aminolaevulinic acid-photodynamic therapy (ALA-PDT) also has limitations in the anal canal. Holmium yttrium aluminum garnet (Ho: YAG) laser with fiber is found to be effective at removing canal lesions, and may create suitable conditions for ALA-PDT. Read More

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http://dx.doi.org/10.1016/j.pdpdt.2020.101696DOI Listing

[Differential diagnosis of hemorrhoidal disease].

Authors:
A Herold

Hautarzt 2020 Apr;71(4):269-274

EDZ Mannheim, Bismarckplatz 1, 68165, Mannheim, Deutschland.

Hemorrhoidal disease is one of the most common illnesses in industrialized nations. Up to 70% of adults suffer from the disease once in their lifetime. This underlines the necessity and importance of knowing about the differential diagnosis of hemorrhoids. Read More

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http://dx.doi.org/10.1007/s00105-020-04553-yDOI Listing

Comorbidities associated with HPV infection among people living with HIV-1 in the southeastern US: a retrospective clinical cohort study.

BMC Infect Dis 2020 Feb 14;20(1):144. Epub 2020 Feb 14.

Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, 35242, USA.

Background: The southeastern US is an epicenter for incident HIV in the US with high prevalence of human papillomavirus (HPV) co-infections. However, epidemiologies of HPV-associated clinical conditions (CC) among people living with HIV-1 infection (PLWH) are not fully known.

Methods: Electronic medical records (EMR) of PLWH attending one of the leading HIV clinics in the southeastern US between 2006 and 2018 were reviewed and analyzed. Read More

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http://dx.doi.org/10.1186/s12879-020-4822-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023731PMC
February 2020

Enhanced Glycogen Metabolism Supports the Survival and Proliferation of HPV-Infected Keratinocytes in Condylomata Acuminata.

J Invest Dermatol 2020 Jan 29. Epub 2020 Jan 29.

Department of Dermatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address:

Condylomata acuminata (CA) is caused by human papillomavirus (HPV) infections of keratinocytes and is a common sexually transmitted disease. The main clinical feature and risk of CA is the high recurrence of genital warts formed by infected keratinocytes. Metabolic reprogramming of most types of mammalian cells including keratinocytes can provide energy and intermediates essential for their survival. Read More

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http://dx.doi.org/10.1016/j.jid.2020.01.010DOI Listing
January 2020

Estimating nationwide cases of sexually transmitted diseases in 2015 from sentinel surveillance data in Japan.

BMC Infect Dis 2020 Jan 28;20(1):77. Epub 2020 Jan 28.

Department of Medical Statistics, Toho University, Tokyo, Japan.

Background: The rates of newly diagnosed cases of sexually transmitted diseases, including genital chlamydial infection and gonorrhea, are important for prevention and control of these diseases. However, nationwide rates are not reported in Japan.

Methods: We used the number of cases of sexually transmitted diseases reported by nationwide sentinel surveillance in 2015, together with the number of all disease outpatients in September 2014 at all medical institutions, drawn from the Survey of Medical Institutions of Japan. Read More

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http://dx.doi.org/10.1186/s12879-020-4801-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986098PMC
January 2020

[Preventing cancer: The role of Papillomavirus vaccination in the general population].

Bull Cancer 2020 Jan 22;107(1):10-20. Epub 2020 Jan 22.

Infovac, CHI de Créteil, 40, avenue de Verdun, 94000 Créteil, France.

Papillomavirus (HPV), the first sexually transmitted disease in the world, is the main infectious agent responsible for cancer (6300 per year, in France). The cycle of HPV infection - >precancerous lesions - >cancer is well documented with regard to the cervix (cf. Nobel Prize in 2008). Read More

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http://dx.doi.org/10.1016/j.bulcan.2019.12.006DOI Listing
January 2020

Coexistence of Anogenital Psoriasis and Genital Warts - Is There an Optimal Treatment?

Acta Dermatovenerol Croat 2019 Dec;27(4):270-272

Assoc. Prof. Suzana Ljubojević Hadžavdić, MD, PhD, Department of Dermatology and Venereology, Zagreb University Hospital Center, University of Zagreb School of Medicine, Šalata 4, 10000 Zagreb, Croatia;

The prevalence of psoriasis is 2% of the world's population (1). Inverse psoriasis is characterized by the development of erythematous shiny plaques at intertriginous areas of the body. The prevalence of only anogenital involvement appears to be low, but involvement of the anogenital area together with other areas is found in up to 45% of patients with psoriasis (2). Read More

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December 2019

Clinical Efficacy of Combination Therapy with Podophyllotoxin and Liquid Nitrogen Cryotherapy in the Treatment of Genital Warts in Men.

Acta Dermatovenerol Croat 2019 Dec;27(4):250-259

Prof. Zoran Golušin, MD, PhD, University of Novi Sad, Faculty of Medicine, Hajduk Veljkova 3, 21000 Novi Sad, Serbia;

High prevalence, peculiar etiopathogenesis, and ineffective therapies have contributed to the fact that genital warts are one of the most challenging issues in modern medicine. This prospective study was aimed at determining the clinical efficacy of combination therapy with 0.5% podophyllotoxin solution and liquid nitrogen cryotherapy in the local treatment of genital warts in men. Read More

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December 2019

Coexistence of Oncogenic Human Papillomavirus Genotypes in Condylomata Acuminata among Children and Adolescents.

Acta Derm Venereol 2020 Feb 25;100(4):adv00061. Epub 2020 Feb 25.

Department of Dermatology and Allergy, University Hospital of Munich (LMU), DE-80337 Munich, Germany.

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http://dx.doi.org/10.2340/00015555-3407DOI Listing
February 2020

[Development of a squamous cell carcinoma of the urinary bladder after intravesical condylomas].

Aktuelle Urol 2020 Jan 15. Epub 2020 Jan 15.

MVZ OptiPath, Pathologie, Frankfurt am Main.

Background:  The occurrence of intravesical condylomata acuminata has been described as a fairly uncommon, benign epithelial lesion. Reports on progression into a muscle-invasive carcinoma of the bladder are rare.

Case:  We present the case of a 68-year-old man who had a history of intravesical condylomata acuminata over several years and developed a muscle-invasive squamous cell carcinoma of the bladder. Read More

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http://dx.doi.org/10.1055/a-0761-2593DOI Listing
January 2020

The impact of HPV multi-cohort vaccination: Real-world evidence of faster control of HPV-related morbidity.

Vaccine 2020 02 6;38(6):1345-1351. Epub 2020 Jan 6.

HPV-related Epidemiological Research Unit, Department of Research, Cancer Registry of Norway, Oslo University Hospital, P.O. Box 5313 Majorstuen, N-0304 Oslo, Norway. Electronic address:

Background: In 2009, both Norway and Denmark initiated routine quadrivalent human papillomavirus vaccination (qHPV) for 12-year-old girls; however, Denmark also introduced free-of-charge multi-cohort vaccination for older age groups in 2008. We aim to describe trends in genital warts (GWs) incidence rates (IRs) among men and women and qHPV vaccine coverage among women in Norway and Denmark in 2006-2015.

Methods: We linked multiple national health registries in Norway and Denmark via national personal identifiers to access data on GWs incidence and qHPV vaccination among women and men aged 12-35 years residing in Norway and Denmark in 2006-2015. Read More

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http://dx.doi.org/10.1016/j.vaccine.2019.12.016DOI Listing
February 2020

Tuberculous Uveitis, Erythema Induratum, and Persistent Genital Warts in a Female Patient: A Rare Case Report.

Adv Biomed Res 2019 27;8:70. Epub 2019 Nov 27.

Psoriasis Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.

Uveitis and erythema induratum are two uncommon extrapulmonary manifestations of tuberculosis (TB). In most circumstances, we cannot isolate mycobacterium from those sites, so diagnosis is difficult. In the presented case, panuveitis, erythema induratum, and persistent anogenital warts were found concurrently in a 19-year-old girl who had a history of pulmonary TB 10 years ago. Read More

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http://dx.doi.org/10.4103/abr.abr_154_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6909546PMC
November 2019

Verrucous papules on the scrotum.

JAAD Case Rep 2020 Jan 20;6(1):13-15. Epub 2019 Dec 20.

Department of Dermatology, University of Florida College of Medicine, Gainesville, Florida.

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http://dx.doi.org/10.1016/j.jdcr.2019.10.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6931078PMC
January 2020

Genital nevus lipomatosus cutaneous superficialis: A diagnostic challenge in a pediatric patient.

Pediatr Dermatol 2020 Mar 22;37(2):352-354. Epub 2019 Dec 22.

Division of Dermatology, Department of Medicine, University of California, Los Angeles, CA, USA.

Nevus lipomatosus cutaneous superficialis (NLCS) is an idiopathic hamartomatous condition characterized by the presence of mature adipose tissue in the dermis. We report a case of NLCS initially misdiagnosed as condyloma acuminata in a 14-year-old boy. This case highlights classic clinical and histologic features of NLCS. Read More

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http://dx.doi.org/10.1111/pde.14077DOI Listing

Molluscum contagiosum mimicking condyloma acuminata in a renal transplant patient: A unique presentation.

Transpl Infect Dis 2020 Feb 1;22(1):e13235. Epub 2020 Jan 1.

Department of Dermatology, School of Medicine, Pusan National University, Busan, Korea.

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http://dx.doi.org/10.1111/tid.13235DOI Listing
February 2020

[Prevalence and management of condylomas in consulting population in Chile: "DIACON study"].

Rev Chilena Infectol 2019 Jun;36(3):283-291

Unidad de Investigación Clínica Alemana, Facultad de Medicina, Universidad Finis Terrae, Chile.

Introduction: Condylomas or genital warts (GW) are the most frequently diagnosed sexually transmitted infection (STI) in STI centers in Chile, but there are no population statistics available.

Objectives: To describe the prevalence of GW in patients from 18-60 years of age who attend outpatient dermatology, gynecology and urology practice; the demographic characteristics of the patients and the diagnostic and treatment tools.

Methods: A sample of Chilean specialists stratified by region, population and gender of patients was provided with a logbook and answered a questionnaire. Read More

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http://dx.doi.org/10.4067/S0716-10182019000300283DOI Listing

Human papillomavirus genotype distribution in genital warts among women in Harare-Zimbabwe.

J Obstet Gynaecol 2020 Aug 2;40(6):830-836. Epub 2019 Dec 2.

Department of Obstetrics and Gynaecology, University of Zimbabwe College of Health Sciences, Harare, Zimbabwe.

This study aimed to determine the prevalence of HPV genotypes in genital warts among women in Harare, Zimbabwe. Women aged 18-45 years attending gynaecology and genitourinary clinics with a clinical diagnosis of genital-warts were recruited. HPV-DNA was extracted from tissue biopsies. Read More

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http://dx.doi.org/10.1080/01443615.2019.1673710DOI Listing

Staged resection in the management of HIV-related anogenital giant condyloma acuminatum. A case report.

Ann Med Surg (Lond) 2019 Dec 1;48:73-76. Epub 2019 Nov 1.

Department of Surgery, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latiff, Bandar Tun Razak, 56000, Kuala Lumpur, Malaysia.

Introduction: Giant condyloma acuminata (GCA), also known as Bushke-Lowenstein tumour, is a rare disease which affects 0.1% of the population. Although histopathologically benign, it tends to be locally destructive. Read More

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http://dx.doi.org/10.1016/j.amsu.2019.10.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6849151PMC
December 2019

A challenging diagnosis of penile sarcomatoid squamous cell carcinoma.

Dermatol Online J 2019 Oct 15;25(10). Epub 2019 Oct 15.

University of Pittsburgh School of Medicine, Pittsburgh, PA.

We report a patient with penile sarcomatoid squamous cell carcinoma (SCC) initially misdiagnosed as condyloma acuminatum. Sarcomatoid SCC is a rare, aggressive, biphasic cancer that often presents a diagnostic challenge and carries a poor prognosis, especially after a delay in diagnosis. Although sarcomatoid SCC may exhibit a broad range of clinical features, the expression of p63 and keratin 34?E12 is a common finding. Read More

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October 2019

Clinicopathologic features of Buschke-Löwenstein tumor: a multi-institutional analysis of 38 cases.

Virchows Arch 2020 Apr 15;476(4):543-550. Epub 2019 Nov 15.

Department of Pathology, Immunology, and Laboratory Medicine, University of Florida College of Medicine, Gainesville, FL, USA.

Buschke-Löwenstein tumor (BLT) is a rare sexually transmitted disease, mostly described in clinical literature as case reports or small series. Here, we investigated the clinicopathologic features of BLT in a total of 38 cases retrieved from multiple academic institutions. The average age was 47. Read More

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http://dx.doi.org/10.1007/s00428-019-02680-zDOI Listing

Successful treatment of genital warts with cidofovir cream in a pediatric patient with Fanconi anemia.

J Oncol Pharm Pract 2020 Jul 13;26(5):1234-1236. Epub 2019 Nov 13.

Department of Pharmacy, King Hussein Cancer Center, Amman, Jordan.

Introduction: Patients with Fanconi anemia have an increased susceptibility to malignancies associated with human papillomavirus, and thus prevention and early management of human papillomavirus infections in this patient population are crucial.

Case Report: A nine-year-old girl with Fanconi anemia developed genital warts about three years after undergoing haplo-identical stem cell transplant. The transplant was complicated by chronic graft-versus-host disease, and the patient had therefore received multiple immunosuppressants. Read More

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http://dx.doi.org/10.1177/1078155219886924DOI Listing

Effectiveness of topical and ablative therapies in treatment of anogenital warts: a systematic review and network meta-analysis.

BMJ Open 2019 10 31;9(10):e027765. Epub 2019 Oct 31.

BMJ-Technology Assessment Group, London, UK.

Objective: To generate estimates of comparative clinical effectiveness for interventions used in the treatment of anogenital warts (AGWs) through the systematic review, appraisal and synthesis of data from randomised controlled trials (RCTs).

Design: Systematic review and network meta-analysis of RCTs. Search strategies were developed for MEDLINE, Embase, the Cochrane Library and the Web of Science. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-027765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830637PMC
October 2019
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Patterns of incident genital human papillomavirus infection in women: A literature review and meta-analysis.

Int J STD AIDS 2019 11 22;30(13):1246-1256. Epub 2019 Oct 22.

Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA.

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http://dx.doi.org/10.1177/0956462418824441DOI Listing
November 2019

Correlation of interleukin-18 gene polymorphism with the susceptibility of condyloma acuminatum in Chinese population.

Braz J Infect Dis 2019 Nov - Dec;23(6):388-394. Epub 2019 Oct 18.

Department of Dermatology, Qingdao Municipal Hospital Group, Qingdao, Shandong, China. Electronic address:

Host immunogenetic setting is involved in the regulation of human papillomavirus (HPV) infection and development of condyloma acuminatum (CA). We investigated the correlation of two common single nucleotide polymorphisms (SNPs) (-607C/A and -137G/C) of IL-18 with the susceptibility of CA in a large Chinese cohort. Out of 408 CA patients analyzed, 300 had HPV infection transmitted through sexual contact (SC) and 108 through non-sexual contact (NSC). Read More

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http://dx.doi.org/10.1016/j.bjid.2019.09.001DOI Listing
March 2020
1 Read
1.096 Impact Factor

Diode lasers for the treatment of genital warts.

Eur J Dermatol 2019 Aug;29(4):409-416

Department of Dermatology and Allergology, University Hospital of Munich (LMU), Munich, Germany.

Human papillomavirus (HPV) infections are the most common sexually transmitted diseases leading to genital warts. Developing lesions start off as small papules, which then grow larger and protrude, eventually coalescing into plaque-like formations. The aim of this study was to evaluate the efficacy of diode laser coagulation as a treatment for genital warts relative to their number, size, localisation, and recurrence rate. Read More

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http://dx.doi.org/10.1684/ejd.2019.3600DOI Listing
August 2019
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Giant perianal condyloma acuminatum in an infant without sexual abuse.

Arch Pediatr 2019 Nov 10;26(8):473-474. Epub 2019 Oct 10.

Department of Dermatology, Ibn Rochd UHC, 1, quartier des hopitaux, 20000, Casablanca, Morocco.

Giant condyloma acuminatum is rare in infants. We report a case of giant perianal condyloma in a 10-month-old infant without sexual abuse. The patient was treated by surgical excision associated with electrocoagulation with no recurrence after 2 years. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0929693X193014
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http://dx.doi.org/10.1016/j.arcped.2019.09.003DOI Listing
November 2019
9 Reads

Patients With LR-HPV Infection Have a Distinct Vaginal Microbiota in Comparison With Healthy Controls.

Front Cell Infect Microbiol 2019 28;9:294. Epub 2019 Aug 28.

Medical Research & Laboratory Diagnostic Center, Jinan Central Hospital, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China.

Condyloma acuminatum (CA) is a benign epithelium hyperplasia mainly caused by human papillomavirus (HPV), which is now the second most common viral sexually transmitted infection (STI) in China. In total, 90% of CA patients are caused by the low-risk HPV 6 and 11. Aside from low-risk HPV infection there are likely other factors within the local microenvironment that contribute to CA and there has been related research before. Read More

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http://dx.doi.org/10.3389/fcimb.2019.00294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722871PMC
July 2020
4 Reads

Successful nonsurgical treatment of penile Buschke-Löwenstein tumor with 12 weeks of 5% imiquimod alone.

Int J STD AIDS 2019 10 24;30(11):1136-1139. Epub 2019 Sep 24.

Skin Institute & School of Dermatology (SISD), New Delhi, India.

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http://dx.doi.org/10.1177/0956462419855505DOI Listing
October 2019
4 Reads