75,820 results match your criteria Complications of Myocardial Infarction


The 5 and 11 Factor Modified Frailty Indices are Equally Effective at Outcome Prediction Using TQIP.

J Surg Res 2020 Jun 30;255:456-462. Epub 2020 Jun 30.

Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama.

Background: The 5-factor modified frailty index (mFI-5) and the 11-factor modified frailty index (mFI-11) are equally effective in predicting adverse outcomes in the American College of Surgeons National Surgical Quality Improvement Program database. The similarly structured American College of Surgeons Trauma Quality Improvement Program (TQIP) database has not been studied with these two frailty indices. We hypothesized that the mFI-5 and mFI-11 could similarly predict adverse outcomes with TQIP data. Read More

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http://dx.doi.org/10.1016/j.jss.2020.05.090DOI Listing

A Rare Case of Hypereosinophilic Syndrome-Induced Shower Thrombus Responsive to Nilotinib.

Cureus 2020 May 28;12(5):e8341. Epub 2020 May 28.

Internal Medicine, Hospital Corporation of America West Florida GME Consortium, Brooksville, USA.

Hypereosinophilic syndrome (HES) is a rare clinical disease that affects 0.036/100,000 patients, with a minority of patients having associated genetic markers which can encompass PDGFRA/B or FGFR1 mutations. The prognosis is dependent on the timing of diagnosis and early treatment, with a mortality rate ranging from 48% to 75% if there is a delayed diagnosis. Read More

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http://dx.doi.org/10.7759/cureus.8341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325400PMC

Effects of Cardiovascular Risk Factor Variability on Health Outcomes.

Endocrinol Metab (Seoul) 2020 Jun 24;35(2):217-226. Epub 2020 Jun 24.

Department of Endocrinology and Metabolism, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.

Innumerable studies have suggested "the lower, the better" for cardiovascular risk factors, such as body weight, lipid profile, blood pressure, and blood glucose, in terms of health outcomes. However, excessively low levels of these parameters cause health problems, as seen in cachexia, hypoglycemia, and hypotension. Body weight fluctuation is related to mortality, diabetes, obesity, cardiovascular disease, and cancer, although contradictory findings have been reported. Read More

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http://dx.doi.org/10.3803/EnM.2020.35.2.217DOI Listing

Electrocardiographic Predictors of Mortality in Acute Anterior Wall Myocardial Infarction With Right Bundle Branch Block and Right Precordial Q-Waves (qRBBB).

Can J Cardiol 2020 Feb 11. Epub 2020 Feb 11.

Department of Cardiology, Christian Medical College Vellore, Tamil Nadu, India. Electronic address:

Background: Published data on the clinical, electrocardiographic, and angiographic profile of acute anterior-wall ST-elevation myocardial infarction (STEMI) with right bundle branch block with q in leads V1, V2 (qRBBB) are scarce. The aim of this study was to estimate the incidence of short-term mortality and in-hospital complications in acute qRBBB STEMI and identify the electrocardiographic (ECG) predictors of a poor outcome.

Methods: We conducted a single-centre retrospective study among the patients with acute anterior-wall STEMI and qRBBB pattern on ECG. Read More

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http://dx.doi.org/10.1016/j.cjca.2020.02.065DOI Listing
February 2020

Can Clinical and Functional Outcomes Be Improved with an Intelligent "Internet Plus"-Based Full Disease Cycle Remote Ischemic Conditioning Program in Acute ST-elevation Myocardial Infarction Patients Undergoing Percutaneous Coronary Intervention? Rationale and Design of the i-RIC Trial.

Cardiovasc Drugs Ther 2020 Jun 30. Epub 2020 Jun 30.

Department of Rehabilitation Medicine, The First Affiliated Hospital of Nanjing Medical University, No.300 Guangzhou Road, Nanjing, 210029, China.

Background: Acute ST-elevation myocardial infarction (STEMI) is associated with a high incidence of complications as well as a considerable hospitalization rate and economic burden. Preliminary evidence suggests that remote ischemic conditioning (RIC) is a promising non-invasive intervention that may effectively and safely reduce myocardial infarct size, subsequent cardiac events and complications, and mortality. However, RIC's cardio-protective effect remains under debate, especially for single timepoint RIC programs. Read More

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http://dx.doi.org/10.1007/s10557-020-07022-9DOI Listing

Stroke and spinal infarct caused by percutaneous coronary intervention.

BMJ Case Rep 2020 Jun 30;13(6). Epub 2020 Jun 30.

Cardiology, University of Louisville, Louisville, Kentucky, USA.

Acute ischaemic stroke is a known risk of percutaneous coronary intervention (PCI). The incidence of such complications has increased in frequency over the last decade due to higher comorbidity burden and increased complexity of PCI procedures. The overall incidence of post-PCI ischaemic stroke remains low at 0. Read More

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http://dx.doi.org/10.1136/bcr-2020-234804DOI Listing

Impella versus extracorporeal membrane oxygenation for acute myocardial infarction cardiogenic shock.

Cardiovasc Revasc Med 2020 May 30. Epub 2020 May 30.

Department of Cardiology, Henry Ford Hospital, Detroit, MI, United States of America.

Background: Percutaneous ventricular assist devices and extracorporeal membrane oxygenation (ECMO) are increasingly used for mechanical circulatory support (MCS) in patients with acute myocardial infarction with cardiogenic shock (AMI-CS) in hospitals throughout the United States.

Methods: Using the National Inpatient Sample from October 2015 to December 2017, we identified hospital admissions that underwent percutaneous coronary intervention (PCI) and non-elective Impella or ECMO placement for AMI-CS using ICD-10 codes. Propensity-score matching was performed to compare both groups for primary and secondary outcomes. Read More

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http://dx.doi.org/10.1016/j.carrev.2020.05.042DOI Listing

Transcatheter Coil Embolization in 17 Patients with 22 Coronary Artery Fistulas.

Tex Heart Inst J 2020 Apr;47(2):135-139

Department of Interventional Cardiology, Arkansas Heart Hospital, Little Rock, Arkansas 72211.

Coronary artery fistulas are rare anomalies that often become symptomatic with age. They are typically diagnosed incidentally during coronary angiography. The chief nonsurgical treatment is transcatheter coil embolization. Read More

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http://dx.doi.org/10.14503/THIJ-18-6786DOI Listing

Reasons for readmission after hospital discharge in patients with chronic diseases-Information from an international dataset.

PLoS One 2020 30;15(6):e0233457. Epub 2020 Jun 30.

Dr Foster Telstra Health, London, United Kingdom.

Background: Chronic diseases are increasingly prevalent in Western countries. Once hospitalised, the chance for another hospitalisation increases sharply with large impact on well-being of patients and costs. The pattern of readmissions is very complex, but poorly understood for multiple chronic diseases. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0233457PLOS

Neutrophil gelatinase-associated lipocalin is a predictor of complications in the early phase of ST-elevation myocardial infarction.

Med Glas (Zenica) 2020 Aug 1;17(2). Epub 2020 Aug 1.

Urology Clinic, Clinical Centre of the University of Sarajevo, Sarajevo, Bosnia and Herzegovina.

Aim To evaluate a correlation of serum level of neutrophil gelatinase-associated lipocalin (NGAL) to the risk of the occurrence of complications in patients with the early phase of ST-segment elevation myocardical infarction (STEMI) treated with fibrinolytic therapy prior to percutaneous coronary intervention (PCI). Methods A total of 54 patients with the diagnosis of STEMI treated with fibrinolytic therapy (alteplase) prior to PCI were included. Patients were admitted to the Intensive Care Unit (ICU) of Clinic for Heart, Blood Vessel and Rheumatic Diseases in the period January to March 2018. Read More

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http://dx.doi.org/10.17392/1139-20DOI Listing

Perioperative cardiovascular complications rate and activity of coagulation and fibrinolysis among patients undergoing vascular surgery for peripheral artery disease and abdominal aortic aneurysm.

Vascular 2020 Jun 29:1708538120937127. Epub 2020 Jun 29.

Department of Intensive Care and Perioperative Medicine, Jagiellonian University Medical College, Krakow, Poland.

Objectives: To compare preoperative coagulation and fibrinolysis activity and incidence of perioperative complications between patients undergoing vascular procedures for peripheral artery disease and abdominal aortic aneurysm.

Methods: This is a substudy of a prospective observational cohort study (VISION; NCT00512109) in which we recruited patients aged ≥45 years, undergoing surgery for peripheral artery disease and abdominal aortic aneurysm. Blood samples were obtained 24 h preoperatively to measure platelet count, concentrations of coagulation coagulation (fibrinogen, factor VIII, von Willebrand factor:Ristocetin cofactor, antithrombin III), fibrinolysis (dimer D, plasmin-antiplasmin complexes, tissue plasminogen activator) markers and level of soluble CD40 ligand. Read More

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http://dx.doi.org/10.1177/1708538120937127DOI Listing

The impact of optimal medical therapy on patients with recurrent acute myocardial infarction: Subanalysis from the BleeMACS study.

Int J Cardiol 2020 Jun 26. Epub 2020 Jun 26.

Interventional Cardiology, University Clinic of Cardiology, Skopje, Macedonia.

Background: Acute myocardial infarction (AMI) recurrence is still high despite great progress in secondary prevention. Patients with recurrent AMI suffer worse prognosis compared to those with first AMI. The objective was to evaluate the effect of optimal medical therapy (OMT) on these patients with recurrent AMI. Read More

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http://dx.doi.org/10.1016/j.ijcard.2020.06.021DOI Listing

[Therapeutic aspects of the choice of antithrombotic therapy in patients with multifocal lesions of peripheral arteries].

Ter Arkh 2019 Sep 15;91(9):158-164. Epub 2019 Sep 15.

Lomonosov Moscow State University.

The article discusses the features of the development and course of the atherosclerotic process in various vascular basins. Variability of factors such as local hemodynamics, differences in the structure of the arteries can influence the formation of atherosclerotic plaque and the progression of the atherosclerotic process. A better understanding of the nature and causes of these differences can help improve the tactics of treatment and prevention of vascular complications. Read More

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http://dx.doi.org/10.26442/00403660.2019.09.000407DOI Listing
September 2019

[Antihypertensive therapy in men and women in real clinical practice according to the National register].

Ter Arkh 2019 Sep 15;91(9):88-100. Epub 2019 Sep 15.

Myasnikov Institute of Clinical Cardiology, National Medical Research Center of Cardiology.

Hypertension is one of the most important risk factors for cardiovascular diseases (CVD) in the world, including Russia. Current Guidelines for the management of arterial hypertension do not include different theatment strategies for men and women. Gender and age analysis of antihypertensive treatmen in men and women could reveal unreasonable and non - optimal treatment in each group. Read More

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http://dx.doi.org/10.26442/00403660.2019.09.000356DOI Listing
September 2019

[Cardiogenic shock in patients with acute coronary syndrome (data from Russian Federal Acute Coronary Syndrome Registry)].

Ter Arkh 2019 Sep 15;91(9):47-52. Epub 2019 Sep 15.

Myasnikov Institute of Clinical Cardiology, National Medical Research Center of Cardiology.

Mortality in acute coronary syndrome (ACS) and its complications remains high, despite significant advances in the treatment of coronary heart disease and its complications. One of the most life - threatening complications of ACS is cardiogenic shock (CS). CS is an extreme degree of acute heart failure and develops on average in 5-8% of patients hospitalized with ACS. Read More

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http://dx.doi.org/10.26442/00403660.2019.09.000317DOI Listing
September 2019

Evaluating Postoperative Outcomes of Patients Undergoing Elective Procedures in an Ambulatory Surgery Center During the COVID-19 Pandemic.

Aesthet Surg J 2020 Jun 29. Epub 2020 Jun 29.

Plastic Surgery and the Director of the Aesthetic Surgery Fellowship, Department of Plastic Surgery, UT Southwestern Medical Center, Dallas, TX.

Background: Despite the rapid rise of publications pertaining to COVID-19, there is a lack of data examining patient outcomes following elective procedures performed during this pandemic.

Objectives: The purpose of this investigation is to: 1) examine the postoperative outcomes of patients that underwent elective procedures in an ambulatory surgery center during the COVID-19 pandemic; 2) share the preoperative screening and patient selection protocol implemented in our center.

Methods: Elective procedures performed in an ambulatory surgery center between March 1, 2020 and April 16, 2020 were retrospectively reviewed. Read More

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http://dx.doi.org/10.1093/asj/sjaa180DOI Listing

[Hybrid revascularization of the brain and myocardium: risk stratification for in-hospital complications].

Angiol Sosud Khir 2020 ;26(2):118-123

Research Institute for Complex Problems of Cardiovascular Diseases, Kemerovo, Russia.

Aim: The study was aimed at determining efficacy of a new computer program of stratification of the risk for postoperative adverse cardiovascular events in patients with atherosclerotic lesions of coronary and carotid arteries.

Patients And Methods: Based on a mathematical analysis of the outcomes of treatment of patients with atherosclerotic lesions of coronary and carotid arteries over the period from 2011 to 2015, we created a program making it possible to determine a staged or simultaneous policy of revascularization, which was retrospectively and prospectively tested in our medical facility.

Results: Within the frameworks of a clinical example we carried out hybrid revascularization of the brain and myocardium in the scope of percutaneous coronary intervention and carotid endarterectomy. Read More

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http://dx.doi.org/10.33529/ANGIO2020212DOI Listing
January 2020

The Future of Cardioprotection-Pointing Toward Patients at Elevated Risk as the Target Populations.

J Cardiovasc Pharmacol Ther 2020 Jun 29:1074248420937871. Epub 2020 Jun 29.

Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark.

Translation of the cardioprotective effect by pharmacological and mechanical conditioning therapies into improvement of clinical outcome for the patients has been disappointing. Confounding factors like comorbidity and comedications may explain some of the loss in translation. However, the substantial improvement of outcome in disease states involving ischemia-reperfusion injury, that is, planned cardiac surgery, elective percutaneous coronary intervention, and even primary percutaneous coronary intervention for ST-segment myocardial infarction (STEMI), is the most plausible explanation for the missed demonstration of a clinical benefit. Read More

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http://dx.doi.org/10.1177/1074248420937871DOI Listing

Clinical Features and Outcomes of Patients With Chronic Myeloid Leukemia Presenting With Isolated Thrombocytosis: A Systematic Review and a Case From Our Institution.

Cureus 2020 Jun 23;12(6):e8788. Epub 2020 Jun 23.

Hematology and Oncology, Creighton University Arizona Health Education Alliance/Valleywise Health Medical Center, Phoenix, USA.

Chronic myeloid leukemia (CML) represents a common condition in the spectrum of myeloproliferative disorders (MPD). It classically exhibits leukocytosis, but rarely presents with isolated thrombocytosis. This paper is designed to review the clinicopathologic features, treatment, and outcomes of patients with CML who present with isolated thrombocytosis. Read More

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http://dx.doi.org/10.7759/cureus.8788DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314366PMC

Real-World Experience With a Tapered Biodegradable Polymer-Coated Sirolimus-Eluting Stent in Patients With Long Coronary Artery Stenoses.

Cardiol Res 2020 Aug 3;11(4):219-225. Epub 2020 Jun 3.

Department of Cardiology, Ospedale Civile, Cirie, Italy.

Background: Treatment of long coronary stenoses (LCS) with long tapered drug-eluting stents (LT-DES) would offer clinical and economic benefits. However, the feasibility of an interventional strategy based upon the systematic LCS treatment with an LT-DES has not been evaluated so far.

Methods: We performed a multicenter prospective study including consecutive patients with: 1) An LCS > 25 mm at coronary angiography; 2) An attempt to fix the LCS with a single BioMime Morph™ stent, a novel LT-DES available from 30 to 60 mm long. Read More

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http://dx.doi.org/10.14740/cr1055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295557PMC

Incidence and risk factors of in-hospital prosthesis-related complications following total hip arthroplasty: a retrospective Nationwide Inpatient Sample database study.

Int Orthop 2020 Jun 27. Epub 2020 Jun 27.

Division of Orthopaedic Surgery, Department of Orthopaedics, Nanfang Hospital, Southern Medical University, 1838 Guangzhou Avenue, Guangzhou, 510515, Guangdong, China.

Purpose: The occurrence of prosthesis-related complications (PRCs) after total hip arthroplasty (THA) is devastating, commonly meaning implant failure and revision surgery. The purpose was to examine the incidence and risk factors of in-hospital PRCs following THA using a large-scale national database.

Methods: A retrospective database analysis was performed based on Nationwide Inpatient Sample (NIS) from 2005 to 2014. Read More

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http://dx.doi.org/10.1007/s00264-020-04682-yDOI Listing

Efficacy and safety of intracoronary prourokinase during percutaneous coronary intervention in treating ST-segment elevation myocardial infarction patients: a randomized, controlled study.

BMC Cardiovasc Disord 2020 Jun 26;20(1):308. Epub 2020 Jun 26.

Department of Cardiology, The Second Hospital of Hebei Medical University, 215 West Heping Road, Shijiazhuang, 050000, China.

Background: Prourokinase is a single-chain plasminogen activator presenting with fewer hemorrhagic complications and reduced reocclusion rate compared with the conventional fibrinolytic agents in patients with coronary artery disease. However, prourokinase intracoronary injection during PCI for treating patients with ST-segment elevation myocardial infarction (STEMI) is rarely investigated. Therefore, this study aimed to evaluate the efficacy and safety of intracoronary prourokinase during the percutaneous coronary intervention (PCI) in treating STEMI patients. Read More

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http://dx.doi.org/10.1186/s12872-020-01584-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7318521PMC

Intraaortic Balloon Pump Counterpulsation, Part I: History, Technical Aspects, Physiologic Effects, Contraindications, Medical Applications/Outcomes.

Anesth Analg 2020 Jun 15. Epub 2020 Jun 15.

Department of Anesthesia and Critical Care, University of Chicago, Chicago, Illinois.

Intraaortic balloon pump counterpulsation is the most common form of mechanical circulatory support used in patients with myocardial ischemia and cardiogenic shock. The physiologic principles of counterpulsation include diastolic augmentation of aortic pressure and systolic reduction of left ventricular afterload, resulting in hemodynamic benefits through increased coronary perfusion pressure and improved myocardial oxygen balance in patients with myocardial ischemia. Major trials have failed to conclusively demonstrate improvements in morbidity and mortality with counterpulsation therapy for patients with acute myocardial infarction (MI), cardiogenic shock, and/or severe coronary artery disease undergoing revascularization therapy, and the debate over its applications continues. Read More

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http://dx.doi.org/10.1213/ANE.0000000000004954DOI Listing

Impact of coronary lesion complexity in percutaneous coronary intervention: one-year outcomes from the large, multicentre e-Ultimaster registry.

EuroIntervention 2020 Jun 25. Epub 2020 Jun 25.

Keele Cardiovascular Research Group, Centre for Prognosis Research, Institutes of Applied Clinical Science and Primary Care and Health Sciences, Keele University, Keele, Newcastle, United Kingdom.

Aims: The present study sought to examine the prevalence, clinical characteristics and one-year outcomes of patients undergoing percutaneous coronary intervention (PCI) to complex lesions (multivessel PCI, ≥3 stents, ≥3 lesions, bifurcation with ≥2 stents, total stent length >60 mm or chronic total occlusion [CTO]) in a prospective multicentre registry.

Methods And Results: Using the e-Ultimaster multicentre registry, a post hoc subgroup analysis was performed on 35,839 patients undergoing PCI, stratified by procedure complexity, and further by number and type of complex features. Overall, complex PCI patients (n=9,793, 27. Read More

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http://dx.doi.org/10.4244/EIJ-D-20-00361DOI Listing

Potassium binders for chronic hyperkalaemia in people with chronic kidney disease.

Cochrane Database Syst Rev 2020 Jun 26;6:CD013165. Epub 2020 Jun 26.

Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy.

Background: Hyperkalaemia is a common electrolyte abnormality caused by reduced renal potassium excretion in patients with chronic kidney diseases (CKD). Potassium binders, such as sodium polystyrene sulfonate and calcium polystyrene sulfonate, are widely used but may lead to constipation and other adverse gastrointestinal (GI) symptoms, reducing their tolerability. Patiromer and sodium zirconium cyclosilicate are newer ion exchange resins for treatment of hyperkalaemia which may cause fewer GI side-effects. Read More

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http://dx.doi.org/10.1002/14651858.CD013165.pub2DOI Listing

Cancer-specific ischemic complications in elderly patients with atrial fibrillation. Data from the prospective ATHERO-AF study.

Int J Cancer 2020 Jun 25. Epub 2020 Jun 25.

Department of Clinical, Internal, Anesthesiologic, and Cardiovascular Sciences, Sapienza University of Rome, Rome, Italy.

Cancer may complicate the clinical course of non-valvular atrial fibrillation (AF) but its association with cardiovascular events (CVEs) is still unclear. We performed a prospective cohort study including 2092 consecutive AF patients on vitamin K antagonists. Principal endpoint was the occurrence of CVEs including fatal/non-fatal myocardial infarction (MI) and ischemic stroke/TIA and cardiovascular death. Read More

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http://dx.doi.org/10.1002/ijc.33179DOI Listing

Mitral valve surgery for ischemic papillary muscle rupture: outcomes from the Japan cardiovascular surgery database.

Gen Thorac Cardiovasc Surg 2020 Jun 25. Epub 2020 Jun 25.

Japan Cardiovascular Surgery Database Organization, Tokyo, Japan.

Background: Ischemic papillary muscle rupture (PMR) is a catastrophic complication following acute myocardial infarction (AMI). We evaluated early outcomes of PMR by using data from the Japan Cardiovascular Surgery Database, a nationwide Japanese registry.

Methods: We retrospectively analyzed data from 196 patients diagnosed with PMR following AMI in Japan between January 2014 and December 2017. Read More

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http://dx.doi.org/10.1007/s11748-020-01418-yDOI Listing

Electrocardiographic features of patients with COVID-19 pneumonia.

Eur J Intern Med 2020 Jun 20. Epub 2020 Jun 20.

Fondazione Umbra Cuore e Ipertensione-ONLUS and Division of Cardiology, Hospital S. Maria della Misericordia, Perugia - Italy.

Background: . The electrocardiographic (ECG) changes which may occur during hospitalization for COVID-19 have not yet been comprehensively assessed.

Patients And Methods: . Read More

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http://dx.doi.org/10.1016/j.ejim.2020.06.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305928PMC

Quantitative proteomic analysis of human plasma using tandem mass tags to identify novel biomarkers for herpes zoster.

J Proteomics 2020 Jun 30;225:103879. Epub 2020 Jun 30.

Department of Anesthesiology and Pain Research center, The Affiliated Hospital of Jiaxing University, Jiaxing 314001, China. Electronic address:

Herpes zoster (HZ), commonly called shingles, it is a distinctive syndrome caused by reactivation of varicella zoster virus (VZV). A better understanding of the biological characteristics of HZ patients can help develop new targeted therapies to improve the prognosis. High-throughput proteomics technology can deeply study the molecular changes in the development and progression of HZ disease and integrate different levels of information, this is important to help make clinical decisions. Read More

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http://dx.doi.org/10.1016/j.jprot.2020.103879DOI Listing

Platelet Transfusion in Cardiac Surgery: A Systematic Review and Meta-Analysis.

Ann Thorac Surg 2020 Jun 22. Epub 2020 Jun 22.

Critical Care and Medicine, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.

Background: Blood transfusion is a well-established independent risk factor for mortality in patients undergoing cardiac surgery but the impact of platelet transfusion is less clear. We performed a systematic review and meta-analysis of observational studies comparing outcomes of patients who received platelet transfusion following cardiac surgery.

Methods: We searched MEDLINE and EMBASE databases to January 2019 for studies comparing peri-operative outcomes in patients undergoing cardiac surgery with and without platelet transfusion. Read More

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http://dx.doi.org/10.1016/j.athoracsur.2020.04.139DOI Listing

Increased Prevalence, Complications, and Costs of Smokers Undergoing Total Knee Arthroplasty.

J Knee Surg 2020 Jun 24. Epub 2020 Jun 24.

Department of Orthopaedic Surgery, Cedars-Sinai Medical Center, Los Angeles, California.

Given a national push toward bundled payment models, the purpose of this study was to examine the prevalence as well as the effect of smoking on early inpatient complications and cost following elective total knee arthroplasty (TKA) in the United States across multiple years. Using the nationwide inpatient sample, all primary elective TKA admissions were identified from 2012 to 2014. Patients were stratified by smoking status through a secondary diagnosis of "tobacco use disorder. Read More

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http://dx.doi.org/10.1055/s-0040-1713128DOI Listing

Frequency of Right Ventricular Infarction in Inferior Wall Myocardial Infarction.

Cureus 2020 May 22;12(5):e8238. Epub 2020 May 22.

Internal Medicine, Bahawal Victoria Hospital, Quaid-E-Azam Medical College, Bahawalpur, PAK.

Background Ischemic heart disease, particularly inferior wall myocardial infarction (IWMI), is a significant issue in cardiac health. It can further add up to the morbidity and mortality when it is associated with right ventricular infarction (RVI). Elevated ST-segment elevations in the right chest lead number, three (V3R), and four (V4R), can be used to diagnose right ventricular infarction (RVI). Read More

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http://dx.doi.org/10.7759/cureus.8238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306669PMC

Clinical and economic burden of postsurgical complications of high-risk surgeries: A cohort study in Thailand.

J Med Econ 2020 Jun 25. Epub 2020 Jun 25.

Department of Pharmacotherapy, College of Pharmacy, University of Utah, UT, USA.

This study aimed to understand the clinical and economic burden associated with postsurgical complications in high-risk surgeries in Thailand. A cost and outcome study was conducted using a retrospective cohort database from 4 tertiary hospitals. All patients with high-risk surgeries visiting the hospitals from 2011 to 2017 were included. Read More

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http://dx.doi.org/10.1080/13696998.2020.1787420DOI Listing

COVID-19 Pandemic: Cardiovascular Complications and Future Implications.

Am J Cardiovasc Drugs 2020 Jun 23. Epub 2020 Jun 23.

Westchester Medical Center, Valhalla, NY, USA.

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is now a global pandemic with the highest number of affected individuals in the modern era. Not only is the infection inflicting significant morbidity and mortality, but there has also been a significant strain to the health care system and the economy. COVID-19 typically presents as viral pneumonia, occasionally leading to acute respiratory distress syndrome (ARDS) and death. Read More

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http://dx.doi.org/10.1007/s40256-020-00420-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310596PMC
June 2020
2.203 Impact Factor

Comparative Effectiveness and Costs of Enoxaparin Monotherapy Versus Unfractionated Heparin Monotherapy in Treating Acute Coronary Syndrome.

Am J Cardiovasc Drugs 2020 Jun 23. Epub 2020 Jun 23.

Duke University School of Medicine, Livongo Health, Durham, NC, USA.

Background: Enoxaparin and unfractionated heparin (UFH) are guideline-recommended anticoagulants for patients with acute coronary syndrome (ACS), including unstable angina (UA) and myocardial infarction with (STEMI) or without ST-segment elevation (NSTEMI). Prior efficacy and safety evidence are mainly from clinical trials. Economic data are insufficient. Read More

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http://dx.doi.org/10.1007/s40256-020-00419-9DOI Listing

Effect of Intraoperative Dexamethasone on Major Complications and Mortality Among Infants Undergoing Cardiac Surgery: The DECISION Randomized Clinical Trial.

JAMA 2020 06;323(24):2485-2492

E. N. Meshalkin National Medical Research Center, Novosibirsk, Russia.

Importance: Corticosteroids are widely used in pediatric cardiac surgery to blunt systemic inflammatory response and to reduce complications; nevertheless, their clinical efficacy is uncertain.

Objective: To determine whether intraoperative administration of dexamethasone is more effective than placebo for reducing major complications and mortality during pediatric cardiac surgery.

Design, Setting, And Participants: The Intraoperative Dexamethasone in Pediatric Cardiac Surgery was an investigator-initiated, double-blind, multicenter randomized trial that involved 4 centers in China, Brazil, and Russia. Read More

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http://dx.doi.org/10.1001/jama.2020.8133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312411PMC

Post-infarct left ventricular thrombosis is mechanistically related to ventricular wall rupture.

Med Hypotheses 2020 Jun 1;144:109938. Epub 2020 Jun 1.

Department of Physiology and Pathophysiology, College of Basic Medical Sciences, Xian Jiaotong University Health Science Center, Xian, China; Baker Heart and Diabetes Institute, Melbourne, Australia. Electronic address:

Left ventricular thrombus (LVT) after acute myocardial infarction (AMI) remains to be a common complication bearing adverse prognostic implication. Majority of LVT occurs within the first week after AMI. Over decades, the regional stasis of blood flow is regarded as the main reason for LVT formation. Read More

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http://dx.doi.org/10.1016/j.mehy.2020.109938DOI Listing

Left Ventricular Thrombosis: New Perspectives on an Old Problem.

Eur Heart J Cardiovasc Pharmacother 2020 Jun 22. Epub 2020 Jun 22.

Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua Medical School, Padua Italy.

Left ventricular thrombosis (LVT) is a major risk factor for systemic thromboembolism and might complicate both the acute and the chronic phase of ischemic heart disease after myocardial infarction and, less frequently, non-ischemic cardiomyopathies. The pathophysiology of thrombus formation is complex and involves the three aspects of Virchow's triad: blood stasis, prothrombotic state and tissue injury. Advances in technology have improved the detection rate of intracardiac thrombi, but several uncertainties still remain regarding the optimal treatment strategy within daily clinical practice. Read More

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http://dx.doi.org/10.1093/ehjcvp/pvaa066DOI Listing

Low-dose Ticagrelor in Patients With High Ischemic Risk and Prior Myocardial Infarction: a Multicenter Prospective Real-World Observational Study.

J Cardiovasc Pharmacol 2020 Jun 17. Epub 2020 Jun 17.

Department of Translational Medical Sciences, University of Campania 'Luigi Vanvitelli', Naples, Italy.

Prolonged dual antiplatelet therapy (DAPT) after 12 months in patients with prior myocardial infarction is attractive to reduce long-term ischemic complications. In the PEGASUS-TIMI 54, the use of low-dose ticagrelor (60 mg b.i. Read More

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http://dx.doi.org/10.1097/FJC.0000000000000856DOI Listing

Impact of Successful Chronic Total Occlusion Percutaneous Coronary Interventions on Subsequent Clinical Outcomes.

J Invasive Cardiol 2020 Jun 22. Epub 2020 Jun 22.

Minneapolis Heart Institute, 920 E 28th Street #300, Minneapolis, Minnesota 55407 USA.

Background: The impact of chronic total occlusion (CTO) percutaneous coronary intervention (PCI) on angina and subsequent incidence of major adverse cardiovascular event (MACE) rate remains controversial.

Methods: We compared patient- reported angina change and the incidence of MACE (defined as death, myocardial infarction [MI], target-vessel revascularization) between successful vs failed CTO-PCI in 1612 patients participating in a large, multicenter registry.

Results: CTO-PCI was successful in 1387 patients (86%). Read More

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Comparison of Outcomes of Transcatheter Aortic Valve Implantation in Patients ≥85 Years Versus Those <85 Years.

Am J Cardiol 2020 May 26. Epub 2020 May 26.

Invasive Cardiology Unit, "Pineta Grande" Hospital, Castel Volturno, Caserta, Italy.

The differential outcomes across the age spectrum of transcatheter aortic valve implantation (TAVI) recipients are still debated. Aim of the study was to evaluate the clinical outcomes of oldest-old patients undergoing TAVI in the large "Registro Italiano GISE sull'impianto di Valvola Aortica Percutanea (RISPEVA)" registry. A total of 3,507 patients were stratified according to age: 1,381 were ≥85 years, 2,126 were <85 years. Read More

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http://dx.doi.org/10.1016/j.amjcard.2020.05.033DOI Listing

[Hypotension - a complication of subarachnoid anesthesia especially dangerous in patients aged].

Pol Merkur Lekarski 2020 Jun;48(285):215-220

Medical University of Warsaw, Poland: Departament of Anaesthesiology and Intensive Care.

Demographic data clearly show the progressive aging of societies. Problems and specificity of anaesthesia in the elderly becomes a particularly important issue in this context. Spinal anesthesia is a method often used to anesthetize elderly patients, and hypotension is one of its most common early complications. Read More

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Spectrum of neuropsychiatric manifestations in COVID-19.

Brain Behav Immun 2020 Jun 17. Epub 2020 Jun 17.

Department of Neurology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.

Corona Virus Disease 2019 (COVID-19) emerged in December 2019 from Wuhan, China. It typically presents with mild upper respiratory tract infection symptoms and may have life threatening complications, including acute respiratory distress syndrome, acute stroke, myocardial infarction, kidney failure, shock, and even death. Coronavirus infections are known to have neuroinvasive potential with consequent neuropsychiatric manifestations. Read More

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http://dx.doi.org/10.1016/j.bbi.2020.06.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297688PMC
June 2020
5.889 Impact Factor

Cardiogenic shock with resultant multiple organ dysfunction syndrome.

Nursing 2020 Jul;50(7):54-60

Lynn Coletta Simko is an associate professor at Duquesne University School of Nursing in Pittsburgh, Pa, and Alicia L. Culleiton is a faculty member at the Ohio Valley Hospital School of Nursing in McKees Rocks, Pa.

The prognosis for a patient with multiple organ dysfunction syndrome (MODS)-also known as organ dysfunction or organ failure-is grave, and mortality can be high when three or more organ systems fail. This article reviews ongoing abnormalities of organ-specific parameters and a bedside clinical scoring assessment tool to identify the mortality of MODS, focusing on the management of MODS resulting from cardiogenic shock in ICU patients who require support of failing organs to survive. Read More

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http://dx.doi.org/10.1097/01.NURSE.0000580664.82974.cfDOI Listing

Primary PCI in the management of STEMI in sub-Saharan Africa: insights from Abidjan Heart Institute catheterisation laboratory.

Cardiovasc J Afr 2020 Jun 12;31:1-4. Epub 2020 Jun 12.

Intensive Care Unit, Abidjan Heart Institute, Abidjan, Côte d'Ivoire.

Background: Implementation of primary percutaneous coronary intervention (PCI) in sub-Saharan Africa remains a challenging issue. The aim of this study was to report the results of primary PCI and outcomes in the catheterisation laboratory of the Abidjan Heart Institute.

Methods: Between April 2010 and March 2019, all patients aged 18 years presenting to the Abidjan Heart Institute for ST-segment elevation myocardial infarction (STEMI) over the study period and who underwent primary PCI were included. Read More

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http://dx.doi.org/10.5830/CVJA-2020-012DOI Listing

Identifying a Safe Carotid Stump Pressure Threshold for Selective Shunting during Carotid Endarterectomy.

Ann Vasc Surg 2020 Jun 15. Epub 2020 Jun 15.

676N St Clair Street, Suite 650, Division of Vascular Surgery, Department of Surgery, Feinberg School of Medicine, Chicago, IL 60611. Electronic address:

Background: There is no current consensus on the best criteria for selective shunting during carotid endarterectomy (CEA). The choice of continuous neurologic assessment during awake CEA, intraoperative electroencephalogram (EEG), or carotid stump pressure monitoring as the basis for shunt placement is primarily dependent on surgeon preference. Our goal was to define a safe stump pressure threshold as a guide for selective shunting. Read More

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http://dx.doi.org/10.1016/j.avsg.2020.06.002DOI Listing
June 2020
1.029 Impact Factor

National trends of outcomes in transcatheter aortic valve replacement (TAVR) through transapical versus endovascular approach: From the National Inpatient Sample (NIS).

Cardiovasc Revasc Med 2020 May 15. Epub 2020 May 15.

Advocate Illinois Masonic Medical Center, Chicago, IL, United States of America; University of California, San Francisco, San Francisco, CA, United States of America.

Background: To evaluate the trends in complication rates following transcatheter aortic valve replacement (TAVR) procedures according to the type of vascular approach (endovascular vs. transapical) in a large US population sample.

Methods: The National Inpatient Sample (NIS) was queried for all patients diagnosed with aortic stenosis who underwent a TAVR procedure in the United States during the years 2012-2016. Read More

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http://dx.doi.org/10.1016/j.carrev.2020.05.010DOI Listing

Safety and Efficacy of Protamine Administration for Prevention of Bleeding Complications in Patients Undergoing TAVR.

JACC Cardiovasc Interv 2020 Jun;13(12):1471-1480

Heart Center, Department of Medicine II, University Hospital Bonn, Bonn, Germany. Electronic address:

Objectives: The aim of this study was to evaluate whether protamine administration for heparin reversal after transcatheter aortic valve replacement (TAVR) reduces bleeding complications and affects patient outcomes.

Background: Occurrence of major bleeding complications in patients undergoing TAVR is associated with increased morbidity and mortality.

Methods: This study included 873 patients undergoing TAVR, of whom 677 received protamine for heparin reversal. Read More

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http://dx.doi.org/10.1016/j.jcin.2020.03.041DOI Listing

The clinical value of the PRECISE-DAPT score in predicting long-term prognosis in patients with acute myocardial infarction.

Int J Cardiol Heart Vasc 2020 Aug 7;29:100552. Epub 2020 Jun 7.

Department of Cardiovascular Medicine, Fukushima Medical University, Fukushima, Japan.

Background: The predicting bleeding complications in patients undergoing stent implantation and subsequent dual antiplatelet therapy (PRECISE-DAPT) score predicts the risk of bleeding in patients treated with dual antiplatelet therapy after percutaneous coronary intervention. Although the PRECISE-DAPT score is expected to be useful beyond its original field, long-term prognostic value of this score in patients with acute myocardial infarction (AMI) remains unclear. In the current study, we aimed to investigate the performance of the PRECISE-DAPT score in predicting the long-term prognosis in patients with AMI. Read More

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http://dx.doi.org/10.1016/j.ijcha.2020.100552DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287192PMC

Current practice of percutaneous coronary intervention on patients with acute coronary syndrome in Iran: A prospective observational study.

Med J Islam Repub Iran 2020 27;34:13. Epub 2020 Feb 27.

Day hospital, Tehran, Iran.

Frequent Percutaneous Coronary Intervention (PCI) procedures are being performed on a daily basis in Iran. However, no study has been reported on the current PCI practice in patients with acute coronary syndrome (ACS) in Iran. We aimed to describe the clinical characteristics and treatment patterns in Iranian ACS patients treated with PCI. Read More

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http://dx.doi.org/10.34171/mjiri.34.13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293802PMC
February 2020