72,370 results match your criteria Complications of Myocardial Infarction


Comparison of 0.9-mm and 1.4-mm catheters in excimer laser coronary angioplasty for acute myocardial infarction.

Lasers Med Sci 2019 Mar 16. Epub 2019 Mar 16.

Department of Cardiovascular Medichine, Tokyo Medical and Dental Hospital, Tokyo, Japan.

Excimer laser coronary angioplasty (ELCA) is a unique revascularization modality that can vaporize plaque and thrombus. Compared to thrombus aspiration therapy, ELCA is reported to provide better microcirculation and reduced peripheral embolism in treatment for acute coronary syndrome. Excimer laser catheters come in various sizes, and we sought to compare the 0. Read More

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http://dx.doi.org/10.1007/s10103-019-02772-xDOI Listing

C-peptide predicts all-cause and cardiovascular death in a cohort of individuals with newly diagnosed type 2 diabetes. The Skaraborg diabetes register.

Diabetes Res Clin Pract 2019 Mar 13. Epub 2019 Mar 13.

R&D Center Skaraborg Primary Care, Skövde, Sweden.

Aims: To study the association between baseline level of C-peptide and all-cause death, cardiovascular death and cardiovascular complications among persons with newly diagnosed type 2 diabetes.

Methods: The Skaraborg Diabetes Register contains data on baseline C-peptide concentrations among 398 persons <65 years with newly diagnosed type 2 diabetes 1996-1998. National registries were used to determine all-cause death, cardiovascular death and incidence of myocardial infarction and ischemic stroke until 31 December 2014. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01688227183160
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http://dx.doi.org/10.1016/j.diabres.2019.03.014DOI Listing
March 2019
1 Read

Metformin Protects the Heart Against Hypertrophic and Apoptotic Remodeling After Myocardial Infarction.

Front Pharmacol 2019 27;10:154. Epub 2019 Feb 27.

National Institute of Health and Medical Research (INSERM) U1048, Institute of Cardiovascular and Metabolic Diseases, Toulouse, France.

Cardiovascular complications are the most prevalent cause of morbidity and mortality in diabetic patients. Metformin is currently the first-line blood glucose-lowering agent with potential relevance to cardiovascular diseases. However, the underpinning mechanisms of action remain elusive. Read More

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http://dx.doi.org/10.3389/fphar.2019.00154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400884PMC
February 2019

Circulating Heme Oxygenase-1 and Complement Activation in Transplant-Associated Thrombotic Microangiopathy.

Biol Blood Marrow Transplant 2019 Mar 11. Epub 2019 Mar 11.

The First Affiliated Hospital of Soochow University, Jiangsu Institute of Hematology, Suzhou, China; Collaborative Innovation Center of Hematology, Suzhou, China; Key Laboratory of Thrombosis and Hemostasis of Ministry of Health, Suzhou, China; Institute of Blood and Marrow Transplantation, Suzhou, China. Electronic address:

Transplant-associated thrombotic microangiopathy (TA-TMA) is a severe complication in patients following hematopoietic stem cell transplantation (HSCT). The pathogenesis of TA-TMA is still unclear. Previous studies showed that complement activation plays an important role in the development of TA-TMA. Read More

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http://dx.doi.org/10.1016/j.bbmt.2019.03.002DOI Listing

Subclinical thyroid dysfunction and cardiovascular consequences: An alarming wake-up call?

Trends Cardiovasc Med 2019 Mar 5. Epub 2019 Mar 5.

School of Medicine, Athens University, Athens, Greece. Electronic address:

Subclinical thyroid dysfunction (STD), presenting as subclinical hypothyroidism (SHypo) or subclinical hyperthyroidism (SHyper), defined as abnormal serum thyrotropin (TSH) and normal free thyroid hormones, is associated with increased cardiovascular (CV) risk and mortality. Depending on the degree of such dysfunction, atherosclerosis, coronary artery disease, heart failure and cardiac arrhythmias, predominantly atrial fibrillation, characterize both disorders and increase CV and total mortality compared to euthyroid persons. There are some differences in the mechanisms involved in the increased CV risk incurred by each type of STD, with more traditional CV risk factors clustered in SHypo than in SHyper, while the role of the TSH or its absence thereof, together with the respective, even subtle, changes incurred in thyroid hormone concentrations, seem to adversely influence the CV system in both types of STD. Read More

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http://dx.doi.org/10.1016/j.tcm.2019.02.011DOI Listing

Periprocedural Outcomes According to Timing of Clopidogrel Loading Dose in Patients Who Did Not Receive P2Y Inhibitor Pretreatment.

Circ Cardiovasc Interv 2019 Mar;12(3):e007445

Cardiovascular Medicine, Brigham and Women's Hospital Heart and Vascular Center, Harvard Medical School, Boston, MA (D.L.B.).

Background: In patients undergoing percutaneous coronary intervention (PCI), who did not receive P2Y inhibitor pretreatment, the optimal timing of P2Y inhibitor loading dose remains debated. We sought to examine whether the choice of administration of the clopidogrel loading dose before or after the start of PCI had an impact on periprocedural complications, including bleeding.

Methods And Results: The CHAMPION PHOENIX (A Clinical Trial Comparing Cangrelor to Clopidogrel Standard Therapy in Subjects Who Require Percutaneous Coronary Intervention) double-blind randomized trial compared cangrelor with clopidogrel loading dose at the time of PCI. Read More

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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.118.007445DOI Listing
March 2019
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Potential Role of Metal Chelation to Prevent the Cardiovascular Complications of Diabetes.

J Clin Endocrinol Metab 2019 Mar 14. Epub 2019 Mar 14.

Department of Medicine, Tulane University School of Medicine, New Orleans, Louisiana.

Context: For decades, there has been epidemiologic evidence linking chronic toxic metal exposure with cardiovascular disease, suggesting a therapeutic role for metal chelation. Given the lack of compelling scientific evidence however, the indications for metal chelation were never clearly defined. To determine the safety and efficacy of chelation therapy, the National Institutes of Health funded the Trial to Assess Chelation Therapy (TACT). Read More

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http://dx.doi.org/10.1210/jc.2018-01484DOI Listing

The Indigo System in Acute Lower-Limb Malperfusion (INDIAN) Registry: Protocol.

JMIR Res Protoc 2019 Mar 14;8(3):e9972. Epub 2019 Mar 14.

Department of Medicine, Surgery and Neuroscience, University of Siena, Siena, Italy.

Background: Acute lower limb ischemia (ALLI) poses a major threat to limb survival. For many years, surgical thromboembolectomy was the mainstay of treatment. Recent years have brought an endovascular revolution to the management of ALLI. Read More

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http://dx.doi.org/10.2196/resprot.9972DOI Listing
March 2019
1 Read

Inferior Wall ST-elevation Myocardial Infarction Complicated by Ventricular Septal Defect and Free Wall Pseudoaneurysm with Rupture.

Cureus 2018 Dec 31;10(12):e3805. Epub 2018 Dec 31.

Cardiology, Long Island Jewish Forest Hills Hospital, New York, USA.

Myocardial infarction (MI) is associated with complications in spite of appropriate management. The incidence of mechanical complications declined over time secondary to reperfusion therapies, improved control of blood pressure, the use of beta blockers and angiotensin-converting enzyme inhibitors, and aspirin. A high degree of suspicion is required, especially in elderly patients with complications post-PCI (percutaneous coronary intervention). Read More

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http://dx.doi.org/10.7759/cureus.3805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402751PMC
December 2018

The Successful Removal of a Broken Needle as an Unusual Complication of Endobronchial Ultrasound-guided Transbronchial Needle Aspiration (EBUS-TBNA): A Case Report and Literature Review.

J UOEH 2019 ;41(1):35-40

Department of Respiratory Medicine, University of Occupational and Environmental Health, Japan.

Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is recommended for the diagnosis of mediastinal lymph nodes by the American College of Chest Physicians guidelines; however, the guidelines state that this procedure should only be performed by a trained bronchoscopist. Complications related to needle malfunction during the EBUS-TBNA procedure have recently been reported. We herein describe a rare case involving the successful management of a needle breakage that occurred as an unusual complication of EBUS-TBNA. Read More

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http://dx.doi.org/10.7888/juoeh.41.35DOI Listing
January 2019

Mode of anesthesia and major perioperative outcomes associated with vaginal surgery.

Int Urogynecol J 2019 Mar 12. Epub 2019 Mar 12.

The Ohio State University Wexner Medical Center, Female Pelvic Medicine and Reconstructive Surgery, 395 W 12th Ave, 5th Floor, Columbus, OH, 43210, USA.

Introduction And Hypothesis: The primary aim was to compare the incidence of major perioperative complications in women undergoing vaginal reconstructive surgery with general, regional, and monitored anesthesia care using a national database. The secondary aim was to compare length of hospital stay, 30-day readmission rates, urinary tract infections, and reoperation rates between anesthesia types.

Materials And Methods: The National Surgical Quality Improvement Program database was used to study women undergoing vaginal surgery for pelvic floor disorders from 2006 to 2015 via Current Procedural Terminology codes. Read More

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http://link.springer.com/10.1007/s00192-019-03908-x
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http://dx.doi.org/10.1007/s00192-019-03908-xDOI Listing
March 2019
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ST-Elevation Myocardial Infarction (STEMI) in a Patient with Moyamoya Disease.

Case Rep Cardiol 2019 4;2019:7124072. Epub 2019 Feb 4.

Department of Medicine, University of Tennessee Graduate School of Medicine, Knoxville, TN, USA.

Moyamoya disease is a rare condition that is primarily reported in Asian populations, characterized by stenoocclusive intracranial angiopathy with small, fragile, and multiple collateral vessel formation. Extracranial complications, mainly abnormalities within the renal vasculature, have been described; however, there are very few case reports of cardiovascular complications in patients with Moyamoya disease. We report a 26-year-old Caucasian female with known Moyamoya disease who presented with both typical and atypical chest pain, mimicking symptoms of a previous non-ST-elevation myocardial infarction. Read More

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https://www.hindawi.com/journals/cric/2019/7124072/
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http://dx.doi.org/10.1155/2019/7124072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378792PMC
February 2019
1 Read

Three-year outcomes after carotid artery revascularization: Gender-related differences.

Vascular 2019 Mar 12:1708538119836312. Epub 2019 Mar 12.

9 Istituto Auxologico Italiano, IRCCS, Dipartimento di Scienze Cardiovascolari, Neurologiche, Metaboliche, Ospedale San Luca, Milano, Italy.

Objectives: Carotid artery stenosis is thought to cause up to 10% of ischemic strokes. Historically, carotid artery endarterectomy has shown a higher risk of perioperative adverse events for women. More recent trials reported conflicting results regarding the benefit of carotid artery endarterectomy and carotid artery stenting for men and women. Read More

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http://dx.doi.org/10.1177/1708538119836312DOI Listing

Cardiac phenotype in mouse models of systemic autoimmunity.

Dis Model Mech 2019 Mar 8;12(3). Epub 2019 Mar 8.

National Heart and Lung Institute, Imperial College London, London, W12 0NN, UK

Patients suffering from systemic autoimmune diseases are at significant risk of cardiovascular complications. This can be due to systemically increased levels of inflammation leading to accelerated atherosclerosis, or due to direct damage to the tissues and cells of the heart. Cardiac complications include an increased risk of myocardial infarction, myocarditis and dilated cardiomyopathy, valve disease, endothelial dysfunction, excessive fibrosis, and bona fide autoimmune-mediated tissue damage by autoantibodies or auto-reactive cells. Read More

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http://dx.doi.org/10.1242/dmm.036947DOI Listing
March 2019
4.973 Impact Factor

Impact of post-procedural glycemic variability on cardiovascular morbidity and mortality after transcatheter aortic valve implantation: a post hoc cohort analysis.

Cardiovasc Diabetol 2019 Mar 11;18(1):27. Epub 2019 Mar 11.

EA3920, University of Franche-Comte, 25000, Besancon, France.

Background: Glycemic variability is associated with worse outcomes after cardiac surgery, but the prognosis value of early glycemic variability after transcatheter aortic valve implantation is not known. This study was therefore designed to analyze the prognosis significance of post-procedural glycemic variability within 30 days after transcatheter aortic valve implantation.

Methods: A post hoc analysis of patients from our center included in the FRANCE and FRANCE-2 registries was conducted. Read More

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http://dx.doi.org/10.1186/s12933-019-0831-3DOI Listing
March 2019
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Two-Stage Revascularization in Patients with Acute Myocardial Infarction and Massive Coronary Thrombosis.

Kardiologiia 2019 Mar 7;59(2):5-9. Epub 2019 Mar 7.

Сardiology Research Institute, Tomsk National Research Medical Centre; Siberian State Medical University..

Aim: to investigate safety and angiographic efficacy of two-stage revascularization with percutaneous coronary intervention (PCI) with stenting delayed by one day in patients with acute myocardial infarction (MI) and massive coronary thrombosis.

Materials And Methods: We included in this study 12 patients with massive infarct related coronary artery thrombus which length was greater than thrice the vessel diameter in the presence of TIMI grade II-III blood flow as detected by coronary angiography (CAG). The emergency PCI was not performed, and conservative antithrombotic therapy continued for 24 hours. Read More

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http://dx.doi.org/10.18087/cardio.2019.2.10224DOI Listing

Heart valve injury due to radiation therapy.

Kardiologiia 2019 Mar 7;59(2S):56-68. Epub 2019 Mar 7.

I. M. Sechenov First Moscow State Medical University (Sechenov University)..

Relevance: Radiation therapy (RT) plays an important role in oncology, improving the immediate and long-term results of treatment of a number of tumors. One of the most significant complications of RT are lesions of the heart valves.

Objective: To study the variants of valve damage that occur in patients who received radiation therapy for cancer. Read More

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http://dx.doi.org/10.18087/cardio.2656DOI Listing

Complex carotid artery stenosis via enhanced anterior cervical triangle posterior vena jugularisinterna approach.

Pak J Pharm Sci 2019 Jan;32(1(Special)):453-457

Brain Hospital, Shengli Oilfield Central Hospital, Dongying, Shandong Province, China.

The paper discuss the surgical techniques and clinical curative effects of CEA (Carotid Endarterectomy, CEA) under a microscope via anterior cervical triangle posterior vena jugularisinterna approach combining with suspended carotid artery on the treatment of high level and complex carotid artery stenosis. Retrospective analysis was conducted on the clinical data of 21 cases of patients. The far end of carotid artery stenosis section is located above the lower edge of the second cervical vertebra centrum. Read More

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January 2019

Electrochemical cardiovascular platforms: Current state of the art and beyond.

Biosens Bioelectron 2019 Feb 19;131:287-298. Epub 2019 Feb 19.

Univ. Lille, CNRS, Centrale Lille, ISEN, Univ. Valenciennes, UMR 8520-IEMN, F-59000 Lille, France. Electronic address:

Cardiovascular diseases (CVD) remain the leading cause of death within industrialized nations as well as an increasing cause of mortality and morbidity in many developing countries. Smoking, alcohol consumption and increased level of blood cholesterol are the main CVD risk factors. Other factors, such as the prevalence of overweight/obesity and diabetes, have increased considerably in recent decades and are indirect causes of CVD. Read More

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http://dx.doi.org/10.1016/j.bios.2019.02.010DOI Listing
February 2019
2 Reads

Medical complications associated with substance use disorders in patients with type 2 diabetes and hypertension: Electronic health record findings.

Addiction 2019 Mar 9. Epub 2019 Mar 9.

Addiction Sciences Division, Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, 3131 Harvey Avenue, Cincinnati, OH, 45229, USA.

Background And Aims: Screening for substance use disorder (SUD) in general medical settings may be particularly important in patients with comorbid health conditions exacerbated by SUD. This study evaluated whether SUD is associated with type 2 diabetes mellitus (T2DM)-complications in patients with co-occurring T2DM and hypertension.

Design: Analysis of a limited data set obtained through IBM Watson Health Explorys, a platform integrating data from electronic health records. Read More

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http://dx.doi.org/10.1111/add.14607DOI Listing
March 2019
2 Reads

Pretreatment with P2Y12 receptor antagonists in ST-elevation myocardial infarction: a report from the Swedish Coronary Angiography and Angioplasty Registry.

Eur Heart J 2019 Mar 9. Epub 2019 Mar 9.

Department of Cardiology, Sahlgrenska University Hospital, Bruna stråket 16, 41345 Gothenburg, Sweden.

Aims: Pretreatment of patients with ST-elevation myocardial infarction (STEMI) with P2Y12 receptor antagonists is supported by guidelines and is a common practice despite the lack of definite evidence for its benefit.

Methods And Results: Using data from the Swedish Coronary Angiography and Angioplasty Registry on procedures between 2005 and 2016, we stratified all patients who underwent primary percutaneous coronary intervention due to STEMI in Sweden by whether or not they were pretreated with P2Y12 receptor antagonists. We investigated associations between pretreatment with P2Y12 receptor antagonists and the risk of adverse outcomes using propensity score-adjusted mixed-effects logistic regression, which accounted for clustering of patients within hospitals. Read More

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http://dx.doi.org/10.1093/eurheartj/ehz069DOI Listing
March 2019
1 Read

The effect of combining coronary bypass with carotid endarterectomy in patients with unrevascularized severe coronary disease.

J Vasc Surg 2019 Mar 5. Epub 2019 Mar 5.

Division of Vascular and Endovascular Surgery, Massachusetts General Hospital, Boston, Mass. Electronic address:

Objective: Management of significant carotid stenosis in those with symptomatic coronary disease remains controversial. Staged and combined carotid endarterectomy (CEA) with coronary artery bypass grafting has been described. Yet, an understanding of the additive risks of these approaches is poor. Read More

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http://dx.doi.org/10.1016/j.jvs.2018.12.026DOI Listing
March 2019
1 Read

Post-Complex Myocardial Infarct Pseudoaneurysm Rupture and Subsequent Complications.

S D Med 2019 Jan;72(1):16-18

University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota.

Ventricular pseudoaneurysm is an uncommonly encountered complication of myocardial infarction (MI) in the era of percutaneous coronary intervention. Its presentation can be very non-specific, and diagnosis requires a high index of suspicion. Urgent surgical repair is generally warranted to prevent potentially catastrophic complications. Read More

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January 2019
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[Early and late results of coronary artery bypass grafting in coronary artery disease in Concepcion, Chile].

Rev Med Chil 2018 Dec;146(12):1395-1404

Centro Cardiovascular, Hospital Clínico Regional de Concepción: "Dr. Guillermo Grant Benavente", Concepción, Chile.

Background: Coronary artery bypass grafting (CABG) is the best treatment for a large group of patients with coronary artery disease.

Aim: To describe early and late results of patients treated with CABG at our Center.

Patients And Methods: Revision of data bases, surgical protocols and clinical registers of patients operated between January 2006 and December 2008. Read More

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http://dx.doi.org/10.4067/s0034-98872018001201395DOI Listing
December 2018
1 Read

Ventricular septal rupture following myocardial infarction: A potentially fatal complication.

Clin Case Rep 2019 Feb 9;7(2):397-400. Epub 2019 Jan 9.

Second Department of Cardiology "Evangelismos" General Hospital of Athens Athens Greece.

Mechanical complications of acute myocardial infarction include ventricular septal rupture (VSR), free wall rupture, and ischemic mitral regurgitation. Postinfarction VSR is a rare but serious complication of myocardial infarction. VSR has a lower incidence in the era of new reperfusion therapies. Read More

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http://dx.doi.org/10.1002/ccr3.1986DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389501PMC
February 2019
1 Read

Simultaneous pancreas-kidney transplantation and the impact of postoperative complications on hospitalization cost.

Rev Col Bras Cir 2019 Mar 7;46(1):e2096. Epub 2019 Mar 7.

Universidade Federal de São Paulo, Disciplina de Gastroenterologia Cirúrgica, São Paulo, SP, Brasil.

Objective: considering simultaneous pancreas-kidney transplantation cases, to evaluate the financial impact of postoperative complications on hospitalization cost.

Methods: a retrospective study of hospitalization data from patients consecutively submitted to simultaneous pancreas-kidney transplantation (SPKT), from January 2008 to December 2014, at Kidney Hospital/Oswaldo Ramos Foundation (Sao Paulo, Brazil). The main studied variables were reoperation, graft pancreatectomy, death, postoperative complications (surgical, infectious, clinical, and immunological ones), and hospitalization financial data for transplantation. Read More

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http://dx.doi.org/10.1590/0100-6991e-20192096DOI Listing
March 2019
2 Reads

Implantable Cardiac Alert System for Early Recognition of ST-Segment Elevation Myocardial Infarction.

J Am Coll Cardiol 2019 Feb 25. Epub 2019 Feb 25.

Duke University Medical Center and Duke Clinical Research Institute, Durham, North Carolina.

Background: Symptoms remain a poor prompt for acute coronary syndromes (ACS). Timely restoration of perfusion in ST-segment elevation myocardial infarction is associated with improved left ventricular function and survival.

Objectives: This report details the results of ALERTS (AngelMed for Early Recognition and Treatment of STEMI), a multicenter, randomized trial of an implantable cardiac monitor that alerts patients with rapidly progressive ST-segment deviation. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07351097193023
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http://dx.doi.org/10.1016/j.jacc.2019.01.014DOI Listing
February 2019
2 Reads

Current Perspectives in Facilitated Angioplasty.

Am J Ther 2019 Mar/Apr;26(2):e208-e212

Cardiology Department, "Victor Babeş" University of Medicine and Pharmacy, Timişoara, Romania.

Background: Ischemic heart disease represents the most important cause of mortality worldwide, and the management of patients with ST-elevation myocardial infarction (STEMI) still remains a great challenge. For a great number of patients who do not have immediate access to primary percutaneous coronary intervention (PCI), facilitated angioplasty may be a reasonable therapeutic option.

Areas Of Uncertainty: The goal of reperfusion therapy is achieving repermeabilization of the infarct-related artery. Read More

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http://dx.doi.org/10.1097/MJT.0000000000000914DOI Listing
March 2019
5 Reads

Prevalence Of Diabetic Complications In Newly Diagnosed Type 2 Diabetes Patients In Pakistan: Findings From National Registry.

J Ayub Med Coll Abbottabad 2018 Oct-Dec;30(Suppl 1)(4):S652-S658

Sanofi-Aventis Pakistan limited, Karachi, Pakistan.

Background: This study was conducted to assess the prevalence of micro- and macrovascular complications in patients with newly diagnosed type 2 diabetes (T2DM) in Pakistan.

Methods: In this multicentre, observational, cross-sectional disease registry, patients (aged ≥18 years) who were diagnosed at enrolment with T2DM, defined by fasting blood glucose (FBG) ≥126 mg/dL and/or glycated haemoglobin (HbA1c) ≥6.5%, were enrolled. Read More

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March 2019
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A single sequential snake saphenous vein graft versus separate left and right vein grafts in coronary artery bypass surgery: a population-based cohort study from the SWEDEHEART registry†.

Eur J Cardiothorac Surg 2019 Mar 5. Epub 2019 Mar 5.

Department of Cardiothoracic Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden.

Objectives: Our goal was to compare short- and midterm outcomes after coronary artery bypass grafting (CABG) using 2 different revascularization strategies.

Methods: A total of 6895 patients were included who had CABG in Sweden from 2009 to 2015 using the left internal mammary artery to the left anterior descending artery and either a single sequential saphenous vein graft connecting the left and right coronary territories to the aorta (snake graft, n = 2122) or separate vein grafts to both territories (n = 4773). Data were obtained from the Swedish Web System for Enhancement of Evidence-Based Care in Heart Disease Evaluated According to Recommended Therapies (SWEDEHEART) and the Swedish Patient Registry. Read More

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http://dx.doi.org/10.1093/ejcts/ezz057DOI Listing
March 2019
1 Read

Stenting of superior mesenteric and celiac arteries does not increase complication rates after fenestrated-branched endovascular aneurysm repair.

J Vasc Surg 2019 Mar 2. Epub 2019 Mar 2.

Division of Vascular Surgery, Department of Surgery, School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC. Electronic address:

Objective: This study compared complications in patients undergoing fenestrated-branched endovascular aneurysm repair (F-BEVAR) without and with stenting of the superior mesenteric artery (SMA) or celiac artery (CA), with particular attention to the length of coverage above the CA.

Methods: A retrospective review was performed of a prospectively maintained database of patients treated with F-BEVAR for thoracoabdominal aortic aneurysms between July 2012 and May 2017. Data included demographics, risk factors, comorbidities, preoperative aneurysm characteristics, procedural data, and outcomes. Read More

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http://dx.doi.org/10.1016/j.jvs.2018.11.043DOI Listing
March 2019
2 Reads

Spontaneous Resolution of Residual Shunting in 2 Compromised Patients after Amplatzer Occlusion of Postinfarction Ventricular Septal Defects.

Tex Heart Inst J 2019 02 1;46(1):44-47. Epub 2019 Feb 1.

Ventricular septal defect (VSD) is a rare, potentially fatal complication of acute myocardial infarction. When surgical closure is contraindicated, transcatheter closure may be an alternative. Residual shunting after transcatheter closure of postinfarction VSDs has been reported; however, we found few cases of this in patients who also had severe heart failure or hemolysis. Read More

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http://dx.doi.org/10.14503/THIJ-17-6416DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379016PMC
February 2019
1 Read

Dipeptidyl peptidase 4 (DPP-4) inhibitors and cardiovascular outcomes in patients with type 2 diabetes mellitus (T2DM): a systematic review and meta-analysis.

BMC Pharmacol Toxicol 2019 Mar 4;20(1):15. Epub 2019 Mar 4.

Department of Endocrinology, Jingzhou First Peoples Hospital, Jingzhou, Hubei, People's Republic of China.

Background: Dipeptidyl peptidase 4 (DPP-4) inhibitors are newer oral anti-diabetic agents which have been approved by the Food and Drug Administration for the treatment of patients with type 2 diabetes mellitus (T2DM). In this analysis, we aimed to systematically compare the cardiovascular outcomes associated with DPP-4 inhibitors versus non-DPP-4 inhibitor users.

Methods: All English publications that compared the use of DPP-4 inhibitors and that reported cardiovascular outcomes in patients with T2DM were searched using specific terms. Read More

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http://dx.doi.org/10.1186/s40360-019-0293-yDOI Listing
March 2019
1 Read

RELATIONSHIP BETWEEN CARBOHYDRATE METABOLISM VALUES AND CALPROTECTIN LEVELS IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION WITH REGARD TO CONCOMITANT TYPE 2 DIABETES MELLITUS.

Georgian Med News 2019 Jan(286):46-49

Kharkiv National Medical University, Department of Internal Medicine No.2; Clinical Immunology and Allergology named after academician L.T. Malaya, Ukraine.

According to literature, the presence of concomitant diabetes mellitus type 2 (DM) is associated with a high frequency of complications in patients with acute myocardial infarction (MI) due to the development of repeated episodes of myocardial ischemia, left ventricular dysfunction, life threatening rhythm disorders, and thromboembolic events Aim: to analyze the state of immuno-inflammation based on the study of calprotectin, as well as to assess the presence and nature of links with carbohydrate metabolism parameters based on the study of blood glucose, insulin and insulin resistance. Patients with AMI in combination with DM 2 were found to have a significant increase in the level of calprotectin by 25.9% (p<0. Read More

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January 2019

Outcomes of Evolut R Versus CoreValve After Transcatheter Aortic Valve Implantation: A Meta-Analysis.

Heart Lung Circ 2019 Jan 28. Epub 2019 Jan 28.

Department of Cardiology, Vascular Center, Guangdong Cardiovascular Institute, Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Peoples Republic of China. Electronic address:

Background: Superiority of the new-generation, self-expanding Evolut R compared with the first-generation CoreValve on outcomes after transcatheter aortic valve implantation (TAVI) is unclear. This meta-analysis sought to investigate the outcomes of Evolut R vs CoreValve after TAVI.

Methods: A systematic review of studies comparing outcomes of Evolut R and CoreValve after TAVI was performed through PubMed, EMBASE and Cochrane Library. Read More

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http://dx.doi.org/10.1016/j.hlc.2018.12.013DOI Listing
January 2019
2 Reads
1.172 Impact Factor

Usefulness of Clopidogrel Loading in Patients Who Underwent Transcatheter Aortic Valve Implantation (from the BRAVO-3 Randomized Trial).

Am J Cardiol 2019 Feb 10. Epub 2019 Feb 10.

Science and Strategy Consulting Group, Basking Ridge, New Jersey. Electronic address:

P2Y-inhibitor initiation with clopidogrel using a loading dose (LD) versus no LD (NLD) provides more rapid inhibition of platelet activation and reduced risk of ischemic events after coronary stenting. Whether a similar beneficial effect is achieved in the setting of transcatheter aortic valve implantation (TAVI) is unknown. We evaluate the effects of preprocedural clopidogrel LD versus no NLD on 48-hour and 30-day clinical outcomes after TAVI. Read More

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http://dx.doi.org/10.1016/j.amjcard.2019.01.049DOI Listing
February 2019
1 Read

Hypertensive Retinopathy: A Prognostic Factor for Morbidity and Mortality after Acute ST Elevation Myocardial Infarction.

J Coll Physicians Surg Pak 2019 Mar;29(3):205-209

Cardiology Unit, Lady Reading Hospital, Peshawar, Pakistan.

Objective: To determine the association between hypertensive retinopathy (HR) and post ST elevation myocardial infarction (STEMI) complications among successfully thrombolysed patients.

Study Design: A cohort study.

Place And Duration Of Study: Cardiology Unit, Lady Reading Hospital, Peshawar, from June 2016 to December 2017. Read More

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http://dx.doi.org/10.29271/jcpsp.2019.03.205DOI Listing
March 2019
4 Reads

Epidural analgesia for adults undergoing cardiac surgery with or without cardiopulmonary bypass.

Cochrane Database Syst Rev 2019 Mar 1;3:CD006715. Epub 2019 Mar 1.

Department of Anesthesiology, Faculty of Medicine, University of Sherbrooke, Sherbrooke, Quebec, Canada.

Background: General anaesthesia combined with epidural analgesia may have a beneficial effect on clinical outcomes. However, use of epidural analgesia for cardiac surgery is controversial due to a theoretical increased risk of epidural haematoma associated with systemic heparinization. This review was published in 2013, and it was updated in 2019. Read More

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http://dx.doi.org/10.1002/14651858.CD006715.pub3DOI Listing
March 2019
2 Reads

Management of Saphenous Vein Graft Disease in Patients with Prior Coronary Artery Bypass Surgery.

Curr Treat Options Cardiovasc Med 2019 Feb 28;21(2):12. Epub 2019 Feb 28.

Division of Cardiovascular Medicine, Department of Medicine, State University of New York at Stony Brook, Stony Brook, NY, USA.

Purpose Of Review: In this review, we summarize the pathogenesis of saphenous venous graft (SVG) failure in patients following coronary artery bypass graft (CABG) surgery. We also provide an update on various aspects of prevention and management of SVG failure.

Recent Findings: Application of perioperative measures and medical therapies to promote SVG patency is crucial to optimize clinical outcomes in patients following CABG. Read More

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http://dx.doi.org/10.1007/s11936-019-0714-7DOI Listing
February 2019
1 Read

The Quest for Type 2 Diabetes Subgroups Identification: Literature Review for a New Subtype Proposal.

Cureus 2018 Dec 24;10(12):e3770. Epub 2018 Dec 24.

Internal Medicine, Colonel Chaabani Hospital, El Menia, DZA.

Type 2 diabetes is considered typically as a heterogeneous disease that englobes the potential different subtypes with distinct pathophysiological mechanisms and/or susceptibility to complications. Some authors have succeeded in the identification of some of these subgroups, but a lot of work remains to be completed. Given the effects of the sympathetic innervation via alpha 1 adrenoceptors on diabetes target organs and the interindividual variability of this receptor sensitivity, the existence of a subtype of type 2 diabetes with hyperactivation of alpha 1 adrenoceptors (HA1A) is proposed. Read More

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http://dx.doi.org/10.7759/cureus.3770DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389034PMC
December 2018
1 Read

Interval From Initiation of Prasugrel to Coronary Angiography in Patients With Non-ST-Segment Elevation Myocardial Infarction.

J Am Coll Cardiol 2019 Mar;73(8):906-914

Institute of Cardiology, Jagiellonian University Medical College, Krakow, Poland.

Background: In the ACCOAST (A Comparison of Prasugrel at PCI or Time of Diagnosis of Non-ST Elevation Myocardial Infarction) trial, the prasugrel pre-treatment strategy versus placebo was associated with excess bleeding complications and no improved ischemic outcome in non-ST-segment elevation myocardial infarction (MI). Whether patients with the longest pre-treatment duration had an ischemic benefit is unknown.

Objectives: This pre-specified analysis of the ACCOAST trial aimed to assess the effect of pre-treatment duration with prasugrel (time from randomization to angiography) on outcomes. Read More

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http://dx.doi.org/10.1016/j.jacc.2018.11.055DOI Listing

90-Day Readmission in Elective Primary Lumbar Spine Surgery in the Inpatient Setting: A Nationwide Readmissions Database Sample Analysis.

Spine (Phila Pa 1976) 2019 Feb 4. Epub 2019 Feb 4.

Department of Orthopedic Surgery, Icahn School of Medicine at Mount Sinai, New York, NY.

MINI: With the increasing popularity of bundled payment models in spine, defining the 90-day post-operative course is of paramount importance. Using the National Readmissions Database (NRD), we identified predictors of 90-day readmission and defined the cost associated with readmission after elective primary lumbar spine surgery in the inpatient setting.

Study Design: Secondary analysis of a large administrative database. Read More

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http://dx.doi.org/10.1097/BRS.0000000000002995DOI Listing
February 2019
1 Read

Robotic radical prostatectomy in 93 cases: Outcomes of the first ERUS robotic urology curriculum trained surgeon in Turkey.

Turk J Urol 2019 Feb 4. Epub 2019 Feb 4.

Clinic of Urology, Ankara Atatürk Training and Research Hospital, Ankara, Turkey.

Objective: This study presents the surgical, oncological, and functional outcomes of the first 93 robotic radical prostatectomy (RARP) procedures performed in Erzurum, Turkey. These procedures were performed by a single surgeon who had completed the European Association of Urology Robotic Urology Section (ERUS) RARP curriculum in an ERUS-certified training center in Ankara.

Material And Methods: The mean patient age was 63. Read More

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http://turkishjournalofurology.com/eng/makale/3461/155/Full-
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http://dx.doi.org/10.5152/tud.2019.24444DOI Listing
February 2019
1 Read

Management of cardiogenic shock complicating acute myocardial infarction: A review.

Clin Cardiol 2019 Feb 26. Epub 2019 Feb 26.

Cleveland Clinic Foundation, Cleveland, OH, USA.

Despite advances in percutaneous coronary interventions and their widespread use, mortality in patients presenting with acute myocardial infarction complicated by cardiogenic shock has remained very high, and treatment options are limited. Limited evidences exist, supporting many of the routinely used therapies in treating these patients. In the present article, we discuss cardiogenic shock complicating myocardial infarction in general and an update on the currently available treatment options, including inotropes and vasopressor, coronary revascularization, mechanical circulatory support devices, mechanical complications and long-term outcomes. Read More

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http://dx.doi.org/10.1002/clc.23168DOI Listing
February 2019
1 Read

Postoperative thrombotic effects of tranexamic acid in open heart surgery.

Ir J Med Sci 2019 Feb 28. Epub 2019 Feb 28.

Department of Anesthesiology and Intensive Care, Health Sciences University Medical School, Istanbul, Turkey.

Background: Following the administration of tranexamic acid, the occurrence of thromboembolic events is a controversial issue.

Aims: In this retrospective cohort study, we aimed to determine the possible thromboembolic complications due to tranexamic acid as a prophylactic method in patients undergoing open heart surgery.

Methods: The data of 172 adult patients undergoing open heart surgery were analyzed. Read More

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http://link.springer.com/10.1007/s11845-019-01991-z
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http://dx.doi.org/10.1007/s11845-019-01991-zDOI Listing
February 2019
4 Reads

Serum Aldosterone as Predictor of Progression of Coronary Heart Disease in Patients Without Signs of Heart Failure After Acute Myocardial Infarction.

Med Arch 2018 Dec;72(6):406-409

Department of Cardiology, General Hospital «Prim. dr. Abdulah Nakas», Sarajevo, Bosnia and Herzegovina.

Introduction: In patients with acute myocardial infarction (AMI) early risk assessment of development of complications is of great importance. It is proven that aldosterone level has a major role in progression of cardiovascular pathology.

Aim: Determination of influence of aldosterone plasma level in the progression of heart disease in patients without signs of heart failure after AMI. Read More

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https://www.ejmanager.com/fulltextpdf.php?mno=302643864
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http://dx.doi.org/10.5455/medarh.2018.72.406-409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340612PMC
December 2018
3 Reads

Randomized Trial Evaluating Percutaneous Coronary Intervention for the Treatment of Chronic Total Occlusion: The DECISION-CTO Trial.

Circulation 2019 Feb 28. Epub 2019 Feb 28.

Division of Cardiology, Heart Institute, Asan Medical Center, University of Ulsan College of Medicine, Republic of Korea.

Background: Procedural results for percutaneous coronary intervention (PCI) in coronary vessels with chronic total occlusion (CTO) have improved in recent years, and PCI strategies have moved toward more complete revascularization with more liberal use of CTO-PCI. However, evidence evaluating CTO-PCI is limited to observational studies and small clinical trials.

Methods: In this open-label, multicenter, randomized, noninferiority trial, PCI-eligible patients were assigned to receive either one of two strategies; PCI or no PCI for the qualifying de novo CTO lesion with the option for PCI of obstructive non-CTO lesions at the discretion of the operator. Read More

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.118.0
Publisher Site
http://dx.doi.org/10.1161/CIRCULATIONAHA.118.031313DOI Listing
February 2019
6 Reads

In-hospital, short-term and long-term adverse clinical outcomes observed in patients with type 2 diabetes mellitus vs non-diabetes mellitus following percutaneous coronary intervention: A meta-analysis including 139,774 patients.

Medicine (Baltimore) 2019 Feb;98(8):e14669

Department of Cardiology, Affiliated Changsha Hospital of Hunan Normal University, The Fourth Hospital of Changsha, Hunan, Changsha.

Background: Several studies have shown that patients with type 2 diabetes mellitus (T2DM) have worse clinical outcomes in comparison to patients without diabetes mellitus (DM) following Percutaneous Coronary Intervention (PCI). However, the adverse clinical outcomes were not similarly reported in all the studies. Therefore, in order to standardize this issue, a meta-analysis including 139,774 patients was carried out to compare the in-hospital, short-term (<1 year) and long-term (≥1 year) adverse clinical outcomes in patients with and without T2DM following PCI. Read More

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http://dx.doi.org/10.1097/MD.0000000000014669DOI Listing
February 2019

Relationship of the ORBIT and HAS-BLED scores with Killip class 3-4 in patients with ST-segment elevation myocardial infarction.

Medicine (Baltimore) 2019 Feb;98(8):e14578

Department of Cardiology, The Second Affiliated Hospital of Nantong University, Nantong.

Heart failure (HF) complicating ST-segment elevation myocardial infarction (STEMI) is recognized as an ominous complication. The HAS-BLED and Outcomes Registry for Better Informed Treatment (ORBIT) scores are used to assess the bleeding risk in patients with anticoagulated atrial fibrillation. This study aimed to investigate the relationship of the ORBIT and HAS-BLED scores with Killip class 3-4 in patients with STEMI. Read More

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http://dx.doi.org/10.1097/MD.0000000000014578DOI Listing
February 2019
2 Reads

Frequency of 30-day readmission and its causes after percutaneous coronary intervention in acute myocardial infarction complicated by cardiogenic shock.

Catheter Cardiovasc Interv 2019 Feb 27. Epub 2019 Feb 27.

Brigham and Women's Hospital Heart & Vascular Center, Harvard Medical School, Boston, Massachusetts.

Background: Survival after percutaneous coronary intervention (PCI) in acute myocardial infarction complicated by cardiogenic shock (AMI-CS) has increased over the years. Short-term readmission rates in this high-risk population remain unknown.

Methods: We queried the United States (U. Read More

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http://dx.doi.org/10.1002/ccd.28161DOI Listing
February 2019
2 Reads
2.107 Impact Factor