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Environ Geochem Health 2021 Apr 30. Epub 2021 Apr 30.

Department of Microbiology, Institute of Biomedicine and Translational Medicine, University of Tartu, Ravila 19, 50411, Tartu, Estonia.

The effects of bath therapy are complex and result from a unique interaction between the aquatic environment and the human body functions. The effect of bath therapy depends on both water temperature and chemical additives (mineral substances and humic substances). Värska Resort Centre, in south-eastern Estonia, uses for the balneotherapy the local curative mud and mineral water. Read More

Hand Surg Rehabil 2021 Apr 18. Epub 2021 Apr 18.

UZ Leuven, Department of Orthopedic Surgery, Herestraat 49, 3000 Leuven, Belgium. Electronic address:

We report on a retrospective cohort of 50 cases of three-ligament tenodesis for scapholunate instability. Fifteen cases (30% of our cohort) needed salvage surgery (11 proximal row carpectomies, 2 partial and 2 total wrist fusions) at an average of 33 months and are considered "failures". Of the 35 remaining cases ("success"), 16 (32% of our cohort) were reviewed at average 111 months and had good functional outcomes (QuickDASH 18/100, PRWE 11/100, pain 1/10, satisfaction 9/10). Read More

Diving Hyperb Med 2021 Mar;51(1):107-110

Czech National Centre for Evidence-Based Healthcare and Knowledge Translation (Cochrane Czech Republic, Czech EBHC; JBI Centre of Excellence, Masaryk University GRADE Centre), Institute of Biostatistics and Analyses, Faculty of Medicine, Masaryk University, Brno, Czech Republic.

A broad spectrum of conditions including neuropathic pain, complex regional pain syndrome (CRPS) and fibromyalgia, have been implicated as causes of chronic pain. There is a need for new and effective treatments that patients can tolerate without significant adverse effects. One potential intervention is hyperbaric oxygen treatment (HBOT). Read More

J Clin Orthop Trauma 2021 Jun 11;17:65-71. Epub 2021 Feb 11.

Department of Orthopaedics, Indraprastha Apollo Hospital, Sarita Vihar, Mathura Road, 110076, New Delhi, India.

Surgeries for Rotator Cuff (RC) pathologies are required for either trauma or degenerative related aetiologies. Various surgical techniques from open to arthroscopic repair, are being undertaken by orthopaedic surgeons. Peri-operative anaesthetic management of the patients undergoing rotator cuff repair requires understanding the surgical procedure and patient status for optimal anaesthetic planning. Read More

Oper Orthop Traumatol 2021 Mar 5. Epub 2021 Mar 5.

Klinik und Poliklinik für Orthopädie und Unfallchirurgie, Universitätsklinikum Bonn, Venusberg-Campus 1, 53127, Bonn, Deutschland.

Objective: Spinal cord stimulation (SCS) targets structures of the dorsal column and dorsal horn of the spinal cord with electrical impulses, thereby, modulating pain perception. For chronic pain patients, e.g. Read More

Reg Anesth Pain Med 2021 May 22;46(5):410-415. Epub 2021 Feb 22.

Department of Orthopedics, The Third Affiliated Hospital of Southern Medical University, Guangzhou, Guangdong, China

Background And Objectives: The periarticular sacroiliac joint (SIJ) technique has become an important area of focus, and the quartering of the SIJ posterior ligamentous region has been proposed as a way to refine this technique. However, detailed nerve distribution combined with the division of the SIJ posterior ligamentous region is lacking. We aimed to explore the innervation of the SIJ posteriorly based on the quartering of the SIJ posterior ligamentous region. Read More

Neuromodulation 2021 Feb 8. Epub 2021 Feb 8.

Department of Anesthesia, Division of Pain Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.

Objectives: Chronic pain syndromes in children can carry significant threats to psychological well-being, opioid overuse, functional impairments, and severe disability. While several high-level studies, almost exclusively in adults, have demonstrated the utility of implantable electrical neuromodulation systems for treating various chronic pain syndromes, there exists a paucity of pediatric-specific evidence. Unfortunately, evidence and practice patterns established from adults may not be fully translatable to children given differences in disease manifestations and anatomical variances. Read More

Neuromodulation 2021 Jan 26. Epub 2021 Jan 26.

Department of Anesthesia, Division of Pain Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.

Background: While the majority of indications and approvals for dorsal root ganglion stimulation (DRGS) are for the refractory management of complex regional pain syndrome (CRPS), emerging evidence has suggested that DRGS may be favorably used for a plethora of other chronic pain phenomena. Consequently, we aimed to characterize the use and efficacy of DRGS for these non-CRPS-related chronic pain syndromes.

Materials And Methods: A systematic review of clinical studies demonstrating the use of DRGS for non-CRPS-related chronic pain syndromes. Read More

Reg Anesth Pain Med 2021 Mar 8;46(3):196-202. Epub 2021 Jan 8.

Anesthesiology and Pain Medicine, Seoul National University Hospital, Jongno-gu, Seoul, Korea (the Republic of).

Background: We aimed to investigate the prevalence of dysautonomia in complex regional pain syndrome (CRPS) via the combined autonomic nervous system (ANS) function tests, including the deep breathing test (DBT), orthostatic test (OST) and sympathetic skin response (SSR).

Method: We retrospectively examined 263 patients who underwent the combined ANS tests to evaluate CRPS between August 2013 and December 2016. Based on the Budapest clinical criteria, patients were stratified into confirmed-CRPS or suspected-CRPS groups. Read More

Reg Anesth Pain Med 2021 Mar 8;46(3):193-195. Epub 2021 Jan 8.

Pain Research Institute, University of Liverpool and Department of Pain Medicine, Walton Centre NHS Foundation Trust, Liverpool, UK.

Georgian Med News 2020 Nov(308):71-79

National Pirogov Memorial Medical University, Vinnytsya, Ukraine.

The aim of the study is to assess the effectivity of the drug «Betargin» in complex management of patients with chronic hepatitis B (CHB) in remission of acute lymphoblastic leukemia (ALL). The research had shown the results of treatment of 41 children with CHB in remission of ALL aged from 3 to 17 years old, who were on dispensary observation in Vinnytsia Regional Children's Clinical Infectious Diseases Hospital during 2013-2017 years. Patients were devided into the following groups: the comparison group (group A), which included 18 children with CHB in remission of ALL, who received basis therapy; the main group (group B) which consisted of 23 patients with CHB in remission of ALL, who got betaine arginine complex («Betargin») in addition to basis therapy. Read More

Anesth Prog 2020 12;67(4):219-225

Director, Dental Anesthesiology Residency Program, Jacobi Medical Center Bronx, New York.

Complex regional pain syndrome (CRPS) is a potentially debilitating form of neuropathic pain that may manifest following a traumatic injury or surgery. CRPS is also known as algodystrophy, causalgia, or reflex sympathetic dystrophy (RSD). Patients describe unbearable burning pain from nonnociceptive stimuli, such as when taking a shower or brushing against another object. Read More

Mil Med Res 2020 12 21;7(1):62. Epub 2020 Dec 21.

Department of Neurosurgery, College of Medicine, Chung-Ang University, Seoul, 06973, South Korea.

Background: The relationship between physical and psychopathological features in complex regional pain syndrome (CRPS) has been a subject of constant interest, but no data are available in adolescents. Therefore, we aimed to identify the factors associated with psychopathology in adolescents with CRPS ahead of military service.

Methods: We retrospectively reviewed all conscription examinees who had completed a Military Personality Inventory (MPI) during a period between February 2013 and December 2016. Read More

J Chiropr Med 2020 Jun 4;19(2):145-151. Epub 2020 Sep 4.

University of Bridgeport College of Chiropractic Outpatient Clinic, Bridgeport, Connecticut.

Objective: The purpose of this case report is to describe the evaluation and treatment of a patient presenting with left upper extremity pain and neck pain after a slip and fall.

Clinical Features: A 56-year-old woman sustained a left distal radius fracture secondary to a slip-and-fall accident. She was placed in a cast for 6 weeks, and after the removal of her cast she developed excruciating left forearm, wrist, hand, and finger pain. Read More

Neuromodulation 2020 Dec 14. Epub 2020 Dec 14.

Memorial Sloan Kettering Cancer Center, Department of Anesthesiology, New York, NY, USA.

Objectives: With the development of percutaneously inserted devices, peripheral nerve stimulation (PNS) has been gaining attention within chronic pain literature as a less invasive neurostimulation alternative to spinal column and dorsal root ganglion stimulation. A majority of current PNS literature focuses on targeting individual distal nerves to treat individual peripheral mononeuropathies, limiting its applications. This article discusses our experience treating dermatomal pain with neurostimulation without needing to access the epidural space by targeting the proximal spinal nerve with peripheral nerve stimulation under ultrasound-guidance. Read More

Eur J Pain 2021 03 11;25(3):693-703. Epub 2020 Dec 11.

Department of Psychology, University of Bath, Bath, UK.

Background: Complex Regional Pain Syndrome (CRPS) is a chronic pain condition that often develops after injury, with a typical onset in adolescence. The impact of chronic pain is far-reaching, with many adolescents reporting atypical developmental trajectories compared with peers. Social Comparison Theory offers a framework for understanding how such comparisons influence well-being, whereby a heightened sense of disparity places adolescents at risk of poor cognitive, affective and social outcomes. Read More

BMC Surg 2020 Dec 1;20(1):306. Epub 2020 Dec 1.

BG Trauma Center Ludwigshafen, Department for Hand-, Plastic- and Reconstructive Surgery, University of Heidelberg, Ludwig-Guttmann-Str. 13, 67071, Ludwigshafen, Germany.

Background: Complex regional pain syndrome (CRPS) is a rare but feared complication in hand surgery. Although multimodal therapy concepts are recommended, there is only low evidence on efficacy of such approaches. Furthermore, recommendations regarding therapy duration are lacking. Read More

Neurol Clin 2021 02 7;39(1):113-131. Epub 2020 Nov 7.

Neuromuscular-EMG Division, Department of Neurology, Loyola University Chicago, Loyola University Medical Center, Stritch School of Medicine, 2160 South First Avenue, Maguire Building - Room 2700, Maywood, IL 60153-3328, USA. Electronic address:

Small fiber neuropathy (SFN) is a prevalent neurologic syndrome. Testing methods have emerged in recent years to better diagnose it, including autonomic tests and skin punch biopsy. SFN can present in a non-length-dependent fashion and can be mistaken for syndromes such as fibromyalgia and complex regional pain syndrome. Read More

Pain Physician 2020 11;23(6):E733

Pain Clinic, Department of Anaesthesia, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Uttar Pradesh, India.

J Orthop Sci 2020 Nov 9. Epub 2020 Nov 9.

Department of Orthopaedic Surgery, Fukushima Medical University School of Medicine, Fukushima City, Fukushima, Japan.

Background: Deterioration of quality of life in patients with chronic pain is difficult to treat. Chronic pain in patients with low quality of life may be "severe" and require multidisciplinary treatments. This study aimed to develop an objective severity discrimination scale based on quality of life measurements to identify patients with "severely disabling" chronic pain. Read More

J Rehabil Med 2020 10 29;52(10):jrm00117. Epub 2020 Oct 29.

Missing (Letter). Read More

Saudi Med J 2020 Oct;41(10):1144-1145

Division of Rheumatology, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon. E-mail.

[No Abstract Available]. Read More

Orthopedics 2020 Nov 1;43(6):e486-e491. Epub 2020 Oct 1.

Complex regional pain syndrome (CRPS) is an uncommon cause of residual pain after total knee arthroplasty (TKA). The presentation is variable, and there is no gold standard diagnostic test. Diagnosis is more difficult after TKA because some classic signs of CRPS may be unreliable and imaging may be difficult to interpret. Read More

NeuroRehabilitation 2020 ;47(3):253-264

Department of Physical Medicine and Rehabilitation, Northwestern Feinberg School of Medicine, Chicago, IL, USA.

Complex regional pain syndrome (CRPS) is a complex disorder that can have a significant impact on the quality of life of a person with this syndrome. The diagnosis and treatment of CRPS are often difficult as there is no one confirmatory test and no one definitive treatment. Currently, the most widely accepted clinical diagnostic criteria are the Budapest criteria, which were developed by expert consensus. Read More

Ther Umsch 2020 Aug;77(6):263-269

Handtherapie und Handtherapieforschung, Universitätsklinik für Handchirurgie und Chirurgie der peripheren Nerven, Inselspital Bern.

Pain assessment of CRPS in Hand Therapy Pain massively controls everyday life of affected persons. In case of a nerve being damaged, pain becomes more complex, as the trophism of the affected skin area may significantly be altered in addition to loss of sensibility and / or motor function. Quantifying pain is, therefore, difficult. Read More

Ther Umsch 2020 Aug;77(6):258-262

Universitäre Klinik für Rheumatologie, Abteilung für Physikalische Medizin und Rheumatologie, Universitätsklinik Balgrist, Zürich.

Pathophysiology and Diagnosis of Chronic Regional Pain Syndrome: What is important for the General Practitioner and the Surgeon? Complex regional pain syndrome (CRPS) describes a variety of painful conditions following an initiating event and appears distally on the affected limb. Characteristically CRPS exceeds the expected clinical course in both magnitude and duration. CRPS affects mainly women between 61 and 70 years and the upper extremity is mainly involved. Read More

Br J Pain 2020 Aug 24;14(3):171-179. Epub 2019 Dec 24.

University of Liverpool and The Walton Centre NHS Foundation Trust, Liverpool, UK.

Introduction: Recruitment into trials in rare chronic pain conditions can be challenging, so such trials consequently are underpowered or fail.

Methods: Drawing from our experience in conducting, to date, the largest academic trial in a rare chronic pain condition, complex regional pain syndrome, we have identified recruitment and retention strategies for successful trial conduct.

Results: We present 13 strategies grouped across the categories of 'setting the recruitment rate', 'networking', 'patient information', 'trial management' and 'patient retention'. Read More

J Oral Sci 2020 Sep 9;62(4):455-457. Epub 2020 Sep 9.

Orofacial Pain and Temporomandibular Disorders, Eastman Institute for Oral Health.

Complex regional pain syndrome (CRPS)-an extremely painful primary pain disorder related to trauma-is rare in the orofacial region. The authors describe a case of orofacial CRPS with a clinical phenotype that fits the Budapest diagnostic criteria. A 39-year-old female patient presented with left-side facial pain that had been untreated for 10 months. Read More