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J Pain Palliat Care Pharmacother 2019 Apr 18:1-4. Epub 2019 Apr 18.

The current recommendation is to use daily doses of vitamin C to prevent the occurrence of the complex regional pain syndrome (CRPS) following a distal radius fracture. The study is a synthesis of the four primary studies that examine this issue. These studies have been previously examined in the meta-analysis literature. Read More

Reg Anesth Pain Med 2019 Apr 16. Epub 2019 Apr 16.

Department of Anesthesiology - Division of Pediatric Anesthesiology, Washington University in Saint Louis School of Medicine, Saint Louis, Missouri, USA.

Objective: Pediatric liver transplantation presents a number of anesthetic challenges, especially in providing adequate perioperative analgesia. In an effort to reduce opioid consumption and improve functional outcomes following pediatric liver transplantation, we have instituted a novel analgesia protocol centered on the provision of continuous regional analgesia with erector spinae plane (ESP) blockade.

Cases: We describe preincisional bilateral ESP catheter placement in two pediatric patients undergoing orthotopic liver transplantation. Read More

Restor Neurol Neurosci 2019 Apr 5. Epub 2019 Apr 5.

Functional Imaging Unit, Center for Diagnostic Radiology, University of Greifswald, Germany.

Background: Patients with a complex regional pain syndrome (CRPS) in the upper limb show a sensory and motor impairment of the hand. Decreased intra-cortical-inhibition (ICI) of the motor representation of the affected hand muscle and decreased somatosensory hand representation size were related to maladaptive plasticity.

Objective: To achieve new insights about CRPS we examined whether these alterations were present in a single cohort. Read More

Pain Med 2019 Apr 15. Epub 2019 Apr 15.

Emotional Information and Communication Technology Association, Seoul, Republic of Korea.

Objectives: In Korea, patients diagnosed with complex regional pain syndrome (CRPS) in the army are typically discharged from the army; however, the course of the disease after discharge is not known. The purpose of this study was to investigate the course of CRPS that occurred in the army and to identify the influences of various clinical and psychosocial factors immediately before discharge on the disease course.

Methods: Clinical profiles and psychosocial status were collected from the medical records of 16 patients with CRPS type 1 who were discharged during the period between March 2017 and April 2018. Read More

Pain 2019 Apr 2. Epub 2019 Apr 2.

College of Science, Health, Engineering and Education, Murdoch University, Perth, Western Australia.

Residual lower limb pain after low back surgery (post-surgical sciatica) and complex regional pain syndrome involving a lower limb (CRPS) are separate conditions, but may share some mechanisms (e.g., tissue inflammation, neuro-immune disturbances and central neuro-plasticity). Read More

Proc (Bayl Univ Med Cent) 2018 Oct 26;31(4):532-533. Epub 2018 Sep 26.

Division of Pain Management, Department of Anesthesiology, Scott & White Medical CenterTempleTexas.

Dorsal root ganglion stimulation is a fairly recent treatment that has emerged in chronic pain management, often used in cases involving patients with complex regional pain syndrome. We describe a 24-year-old woman with severe left hip pain secondary to avascular necrosis in whom multiple treatments failed, including oral analgesics and radiofrequency ablation. A dorsal root ganglion stimulator was implanted with significant pain relief. Read More

J Neuroinflammation 2019 Apr 3;16(1):70. Epub 2019 Apr 3.

Discipline of Anatomy & Histology, School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Room E513, Anderson Stuart Building, Sydney, NSW, 2006, Australia.

Following publication of the original article [1], the authors reported an error in Figure 4 as the wrong figure was used. Read More

Am J Sports Med 2019 Apr 3:363546519831294. Epub 2019 Apr 3.

Department of Orthopaedic Surgery, University Hospital of Saint Étienne, Saint Étienne, France.

Background:: Isolated medial patellofemoral ligament reconstruction (iMPFLR) is increasingly used for the surgical treatment of recurrent patellofemoral instability.

Purpose:: The purpose of this study was to identify the clinical and radiological predictors that can significantly influence the functional outcomes after an iMPFLR.

Study Design:: Case series; Level of evidence, 4. Read More

J Stroke Cerebrovasc Dis 2019 Mar 30. Epub 2019 Mar 30.

Ankara Physical Medicine and Rehabilitation Training and Research Hospital, Department of Physical Medicine and Rehabilitation, Istanbul, Turkey.

Objective: To evaluate whether combining fluidotherapy to conventional rehabilitation program provides additional improvements on pain severity, upper extremity functions, and edema volume in patients with poststroke complex regional pain syndrome (CRPS).

Design: Randomized controlled trial.

Setting: Training and research hospital. Read More

J Neurosurg 2019 Apr;130(4):1039-1049

Pain surgery is one of the historic foundations of neurological surgery. The authors present a review of contemporary concepts in surgical pain management, with reference to past successes and failures, what has been learned as a subspecialty over the past 50 years, as well as a vision for current and future practice. This subspecialty confronts problems of cancer pain, nociceptive pain, and neuropathic pain. Read More

Reumatismo 2019 Apr 1;71(1):31-36. Epub 2019 Apr 1.

Children's Medical Center, Pediatrics Center of Excellence, Tehran; Growth and Development research Center, Tehran University of Medical Sciences.

We discuss the case of a 27-month-old girl afflicted with fibromuscular dysplasia. She presented with hemiatrophy of left upper and lower limbs, nail dystrophy, ulcers on the tips of her toes, cold and painful limbs, foot drop, and hypertension. The initial appearance started at 2 months of age and other diagnoses such as complex regional pain syndrome, reflex sympathetic syndrome, vasculitis and coagulation disorders had been considered. Read More

Rehabilitacion (Madr) 2019 Jan - Mar;53(1):13-19. Epub 2019 Jan 2.

Unidad de Gestión Clínica, Rehabilitación Provincial de Sevilla, Hospital Universitario Virgen del Rocío, Sevilla, España.

Introduction: To evaluate the effectiveness of early capsular ultrasound-guided hydrodilatation (HD) of the proximal interphalangeal or metacarpophalangeal joints in reducing joint stiffness and shortening kinesitherapy, as well as in improving hand functionality.

Material And Methods: We performed a one-year quasi-experimental pretest-posttest study with a control group in patients with proximal interphalangeal or metacarpophalangeal capsulitis in complex regional pain syndrome stages 2 or 3. Inclusion criteria consisted of age over 18 years, visual analogue scale<4 points and the absence of prior treatment. Read More

Medicine (Baltimore) 2019 Mar;98(13):e14990

Department of Rehabilitation Medicine, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, South Korea.

Rationale: Complex regional pain syndrome (CRPS) usually occurs after trauma and surgery but can also occur spontaneously. There are various known pathophysiology and treatment protocols for CRPS. However, there is no established treatment guideline. Read More

Oper Orthop Traumatol 2019 Mar 27. Epub 2019 Mar 27.

Sektion für Fuß- und Sprunggelenkchirurgie, Klinik für Allgemeine, Unfall- und Wiederherstellungschirurgie, LMU München, Ludwig-Maximilians-Universität, Nußbaumstraße 20, 80336, München, Deutschland.

Objective: Repair of the lateral ligament complex of the ankle joint; identification and treatment of intra-articular pathologies.

Indications: Symptomatic chronic lateral ankle instability. Treatment of osteochondral lesions associated with lateral ankle instability. Read More

Am J Hosp Palliat Care 2019 Mar 27:1049909119838974. Epub 2019 Mar 27.

2 Hospice and Palliative Medicine, Ballad Health System, Kingsport, TN, USA.

Pain can have a devastating effect on the quality of life of patients in palliative medicine. Thus far, majority of research has been centered on opioid-based pain management, with a limited empirical evidence for the use of nonopioid medications in palliative care. However, opioid and nonopioid medications such as nonsteroidal anti-inflammatory drugs have their limitations in the clinical use due to risk of adverse effects, therefore, there is a need for more research to be directed to finding an alternative approach to pain management in comfort care setting. Read More

Pain Med 2019 Mar 25. Epub 2019 Mar 25.

Michael G. DeGroote Institute for Pain Research and Care, McMaster University, Hamilton, ON, Canada.

Objective: There is a need for reliable and valid clinical assessment tools for quantifying allodynia in neuropathic pain. Allodynography has been proposed as a useful standardized procedure for clinical assessment of mechanical allodynia. This study (www. Read More

J Orthop 2019 May-Jun;16(3):216-219. Epub 2019 Jan 4.

Centre de Chirurgie Orthopédique, Clinique de Saint-Omer, 71 Rue Ambroise Paré, 62575, Blendecques, France.

Introduction: The synovial wrist ganglion is a particularly common pathology of which the first "complication" is recidivism. The main objective of our study was to determine the rate of recurrence of this pathology in a series of arthroscopic patients. The secondary objective was to assess patient satisfaction well after the operation. Read More

Neurosurg Clin N Am 2019 Apr;30(2):257-264

Department of Neurosurgery, University of Wisconsin Hospitals and Clinics, 600 Highland Avenue, Madison, WI 53792, USA. Electronic address:

Nerve stimulation is a reversible technique that is used successfully for the treatment of traumatic neuropathic pain, complex regional pain syndrome, and craniofacial neuropathic pain. Nerve field stimulation targets painful regions rather than a single nerve and has expanded indications, including axial low back pain. Appropriate patient education and motivation are crucial prior to surgery. Read More

Neurosurg Clin N Am 2019 Apr 18;30(2):169-194. Epub 2019 Feb 18.

Department of Neurosurgery, Albany Medical College, 43 New Scotland Avenue, Albany, NY 12208, USA; Department of Neuroscience and Experimental Therapeutics, Albany Medical College, 43 New Scotland Avenue, Albany, NY 12208, USA. Electronic address:

Spinal cord stimulation (SCS) has been well established as a safe and effective treatment of pain derived from a wide variety of etiologies. Careful patient selection including a rigorous trial period and psychological evaluation are essential. When patients proceed to permanent implantation, various considerations should be made, such as the type of lead, type of anesthesia, and waveform patterns for SCS. Read More

Sci Rep 2019 Mar 19;9(1):4871. Epub 2019 Mar 19.

Department of Orthopedic Surgery, Hanyang University College of Medicine, Seoul, 04763, South Korea.

This study aimed to evaluate the incidence rates of and risk factors for complex regional pain syndrome type 1 (CRPS-1) after surgery for distal radius fractures (DRFs). Using data from January 2007 to December 2014, we analysed the data from the Korean Health Insurance Review and Assessment (HIRA) service. After extracting the data of patients aged ≥18 years whose diagnostic and operation codes for DRFs were entered into the HIRA database, we analysed the incidence rates of and risk factors for CRPS-1. Read More

Pain Med 2019 Mar 19. Epub 2019 Mar 19.

Department of Anesthesiology, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.

Objectives: The aims of this study were to identify the reasons for explanation of spinal cord stimulator (SCS) devices and to further quantify the proportions and time lines of these causes of explantation in order to determine improvement opportunities for the development of best practices. Design. Retrospective, single academic center. Read More

J Neuroinflammation 2019 Mar 18;16(1):63. Epub 2019 Mar 18.

Discipline of Anatomy & Histology, School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Room E513, Anderson Stuart Building, Sydney, NSW, 2006, Australia.

Background: Complex regional pain syndrome (CRPS) is a debilitating condition where trauma to a limb results in devastating persistent pain that is disproportionate to the initial injury. The pathophysiology of CRPS remains unknown; however, accumulating evidence suggests it is an immunoneurological disorder, especially in light of evidence of auto-antibodies in ~ 30% of patients. Despite this, a systematic assessment of all circulating leukocyte populations in CRPS has never been performed. Read More

J Pain Res 2019 6;12:909-914. Epub 2019 Mar 6.

Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea,

Purpose: Complex regional pain syndrome (CRPS) is a rare but refractory pain disorder. Recent advanced information retrieval studies using text-mining and network analysis have suggested nuclear factor kappa B (NFκB) as a possible central mediator of CRPS. The brain is also known to play important roles in CRPS. Read More

J Transl Med 2019 Mar 14;17(1):81. Epub 2019 Mar 14.

Pharmacology & Physiology, Drexel University College of Medicine, 245 North 15th Street, Mail Stop 488, Philadelphia, PA, 19102, USA.

Background: Therapeutic plasma exchange (PE) or plasmapheresis is an extracorporeal procedure employed to treat immunological disorders. Exosomes, nanosized vesicles of endosomal origin, mediate intercellular communication by transferring cargo proteins and nucleic acids and regulate many pathophysiological processes. Exosomal miRNAs are potential biomarkers due to their stability and dysregulation in diseases including complex regional pain syndrome (CRPS), a chronic pain disorder with persistent inflammation. Read More

PLoS One 2019 13;14(3):e0213589. Epub 2019 Mar 13.

University of Groningen, University Medical Center Groningen, Department of Rehabilitation Medicine, Groningen, The Netherlands.

Background: Amputation for longstanding therapy resistant complex regional pain syndrome type-I (CRPS-I) is controversial. Reported results are inconsistent. It is assumed that psychological factors play a role in CRPS-I. Read More

F1000Res 2019 5;8. Epub 2019 Mar 5.

Department of Medicine, Monash University, Clayton, Victoria, 3168, Australia.

The common chronic pain syndromes of fibromyalgia, regional pain syndrome, and complex regional pain syndrome have been made to appear separate because they have been historically described by different groups and with different criteria, but they are really phenotypically accented expressions of the same processes triggered by emotional distress and filtered or modified by genetics, psychology, and local physical factors. Read More

Neuromodulation 2019 Mar 12. Epub 2019 Mar 12.

Marcus Neuroscience Institute, Boca Raton, FL, USA.

Introduction: ACCURATE, a randomized controlled trial comparing dorsal root ganglion (DRG) stimulation to spinal cord stimulation, showed that DRG stimulation is a safe and effective therapy in individuals with lower extremity chronic pain due to complex regional pain syndrome (CRPS) type I or II. Investigators noted that DRG stimulation programming could be adjusted to minimize, or eliminate, the feeling of paresthesia while maintaining adequate pain relief. The present study explores treatment outcomes for DRG subjects who were paresthesia-free vs. Read More

Ann R Coll Surg Engl 2019 Apr 11;101(4):e102-e104. Epub 2019 Mar 11.

Plastic and Reconstructive Surgery Department, Salisbury District Hospital, Salisbury , Salisbury , UK.

Collagenase injection was approved in Europe for use in the treatment of Dupuytren's disease in 2011. Reported adverse effects include skin tears, swelling, pain and complex regional pain syndrome. Here, we present a case of a rare complication of phalangeal fracture following treatment with collagenase clostridium and the resultant digital amputation. Read More

Pain Med 2019 Mar 8. Epub 2019 Mar 8.

Department of Physical Medicine and Rheumatology, Balgrist University Hospital, Zurich, Switzerland.

Objective: First, to determine the number of accident-related complex regional pain syndrome (CRPS) cases from 2008 to 2015 and to identify factors associated with an increased risk for developing CRPS. Second, to analyze the duration of work incapacity and direct health care costs over follow-up periods of two and five years, respectively.

Design: Retrospective data analysis. Read More

J Med Case Rep 2019 Mar 7;13(1):80. Epub 2019 Mar 7.

Department of Surgery, St Elizabeth Catholic General Hospital, Shisong, P.O Box 8, Kumbo - Nso, Bui Division, Northwestern Region, Cameroon.

Background: A case is reported of innocuous intestinal obstruction requiring surgical intervention that was confirmed to be Crohn's disease histopathologically in a resource-constrained rural mission hospital in Cameroon.

Case Presentation: A 70-year man of Kumbo origin from Northwest region of Cameroon with a history of crampy right lower-quadrant abdominal pain, non-bloody, non-mucoid diarrhea alternating with constipation presented to my institution. Abdominal examination of the patient revealed an ill-defined mass in the right iliac fossa and visible peristalsis. Read More

Acta Orthop Belg 2018 Sep;84(3):338-344

Prevention of CRPS-1, a post-traumatic pain syndrome, after a distal radius fracture is important as this syndrome might lead to chronic pain and serious disabilities. In several studies, it was shown that CRPS-1 can be cured with exercise and graded activities. In a prospective cohort study, a home exercise program with progressive loading exercises was applied immediately after cast removal in patients with a distal radius fracture. Read More

Rev Med Suisse 2019 Feb;15(640):495-502

Service de réadaptation de l'appareil locomoteur, Clinique romande de réadaptation suvacare, Grand-Champsec 90, 1950 Sion.

The Complex Regional Pain Syndrome (previously algodystrophy) is a rare affliction that usually affects a distal extremity (hand, foot). It occurs most frequently within weeks following a traumatic injury or stroke. It is a syndromic entity whose diagnosis is based on precise criteria, known as the Budapest criteria, excluding any disease that better explains the symptoms. Read More

Front Neurosci 2019 5;13:19. Epub 2019 Feb 5.

Ashirvad Institute for Pain Management and Research, Mumbai, India.

Anesth Analg 2019 Feb 18. Epub 2019 Feb 18.

From the Department of Anesthesiology, Rush University Medical Center, Chicago, Illinois.

Background: Metformin, an adenosine monophosphate (AMP)-activated protein kinase activator, as well as a common drug for type 2 diabetes, has previously been shown to decrease mechanical allodynia in mice with neuropathic pain. The objective of this study is to determine if treatment with metformin during the first 3 weeks after fracture would produce a long-term decrease in mechanical allodynia and improve a complex behavioral task (burrowing) in a mouse tibia fracture model with signs of complex regional pain syndrome.

Methods: Mice were allocated into distal tibia fracture or nonfracture groups (n = 12 per group). Read More

Pain Rep 2019 Jan-Feb;4(1):e692. Epub 2019 Jan 9.

Department of Neurology, Pain Center, Universidade de São Paulo, São Paulo, Brazil.

Introduction: Chronic pain (CP) is highly prevalent and generally undertreated health condition. Noninvasive brain stimulation may contribute to decrease pain intensity and influence other aspects related to CP.

Objective: To provide consensus-based recommendations for the use of noninvasive brain stimulation in clinical practice. Read More

Scand J Pain 2019 Apr;19(2):257-270

Pain Clinic, Department of Anaesthesiology, Intensive Care and Pain Medicine, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.

Background and aims Complex Regional Pain Syndrome (CRPS) often recovers spontaneously within the first year, but when it becomes chronic, available rehabilitative therapies (pharmacological management, physiotherapy, and psychological intervention) have limited effectiveness. This study examined the effect of a 12-week intensive outpatient rehabilitation on pain relief and function in chronic CRPS patients. Rehabilitation program included memantine and morphine treatment (added to patient's prior pain medication) and concurrent psychological and physiotherapeutic intervention. Read More

Neuromodulation 2019 Feb 20. Epub 2019 Feb 20.

Pain Unit, Anesthesiology and Resuscitation Department, University Care Complex of Salamanca (Complejo Asistencial Universitario de Salamanca), Salamanca, Spain.

Objective: One of the physiopathological hypothesis behind complex regional pain syndrome (CRPS) type I involves the deep-tissue hypoxia of the affected areas. Spinal cord stimulation (SCS) appears to be effective in the treatment of these patients. We evaluated whether ESCS modifies tissue oxygen saturation (StO ) measured with near-infrared spectroscopy (NIRS) in the affected limbs in patients diagnosed with CRPS type I. Read More

J Altern Complement Med 2019 Feb;25(2):141-168

1 National Centre for Naturopathic Medicine, Southern Cross University, Lismore, Australia.

Objective: To summarize the current state of the research evidence for whole-system, multi-modality naturopathic medicine.

Design: A systematic search for research articles from around the world was undertaken using MEDLINE, Embase, CINAHL, AMED, and WHO regional indexes. Naturopathic journals and gray literature were hand searched. Read More

Reg Anesth Pain Med 2019 Mar;44(3):376-387

Department of Pain Management, Cleveland Clinic, Cleveland, OH 44024, USA

This account of the condition now termed complex regional pain syndrome (CRPS) spans approximately 462 years since a description embodying similar clinical features was described by Ambroise Paré in 1557. While reviewing its historical origins, the text describes why it became necessary to change the taxonomies of two clinical syndromes with similar pathophysiologies to one which acknowledges this aspect but does not introduce any mechanistic overtones. Discussed at length is the role of the sympathetic component of the autonomic nervous system (ANS) and why its dysfunction has both directly and indirectly influenced our understanding of the inflammatory aspects of CRPS. Read More

J Surg Orthop Adv 2018 ;27(4):261-268

Department of Orthopaedic Surgery, Wake Forest Baptist Medical Center, Winston-Salem, North Carolina; e-mail:

Ascorbic acid (vitamin C) is an essential micronutrient with evidence supporting its role in bone formation, tissue repair, and collagen production. Its clinical importance to the field of orthopaedic surgery has yet to be fully defined. Several observational studies have shown improved bone density and reduced hip fracture risk with supplementation. Read More

Joint Bone Spine 2019 Feb 15. Epub 2019 Feb 15.

Centre de rhumatologie, hôpital Pierre-Paul-Riquet, CHU de Toulouse, place du Dr-Baylac, TSA 40 031, 31059 Toulouse cedex 9, France; Centre de physiopathologie Toulouse Purpan, Inserm UMR 1043, CHU de Purpan, BP 3028, 31024 Toulouse cedex 3, France.

Pain Med 2019 Feb 18. Epub 2019 Feb 18.

Center for Pain Medicine, Erasmus MC-University Medical Center, Rotterdam, the Netherlands.

Objective: Although complex regional pain syndrome (CRPS) of the knee is comparable to CRPS of the ankle/foot at time of diagnosis, no reports are available concerning the course of knee CRPS. Therefore, this study investigated the clinical course in terms of the symptoms and signs, health-related quality of life (HR-QoL), and work status of patients diagnosed with CRPS of the knee.

Design: Observational, descriptive study. Read More

J Neurosurg 2019 02 15:1-9. Epub 2019 Feb 15.

Department of Plastic & Reconstructive Surgery, Radboud University Medical Center, Nijmegen.

Objective: The aim of this study was to evaluate the self-reported outcome of revision surgery in patients with recurrent and persistent carpal tunnel syndrome (CTS) and to identify predictors of clinical outcome of revision surgery.

Methods: A total of 114 hands in 112 patients were surgically treated for recurrent and persistent CTS in one of 10 specialized hand clinics. As part of routine care, patients were asked to complete online questionnaires regarding demographic data, comorbidities, and clinical severity measures. Read More

Medicine (Baltimore) 2019 Feb;98(7):e14452

Department of Psychiatry, Seoul National University Hospital.

Complex regional pain syndrome (CRPS) and fibromyalgia (FM) share many features. Both can cause severe pain and are considered to have a mechanism of action, including dysfunction of the sympathetic nervous system. However, they have clinical differences in pain range and degree. Read More

Pain 2019 Feb 8. Epub 2019 Feb 8.

Department of Endocrine Research, Medical Hospital I, BG University Hospital Bergmannsheil Bochum, Bochum, Germany.

Local osteopenia and altered bone metabolism are major complications of complex regional pain syndrome (CRPS), but quantitative assessment is difficult unless using X-ray or dual-energy X-ray absorptiometry. Ultrasound-based measurement of bone density (UBD) is a possible alternative but has never been used to detect unilateral disease such as CRPS. Therefore, the main outcome measure of this prospective study was the diagnostic utility of UBD in patients with lower-limb CRPS. Read More

Urologiia 2018 Dec(6):108-114

FGBOU VO Krasnoyarsk State Medical University named after professor V.F. Voyno-Yasenetsky of the Ministry of Health of Russia, Krasnoyarsk, Russia.

Aim: to study the course of chronic abacterial prostatitis with the inflammatory component (CAPIC) depending on the somatotype in men of the first period of mature age taking complex treatment with a use of local and systemic ozone therapy.

Materials And Methods: A total of 306 men of asthenic, normostenic and pyknic somatotypes with CAPIC were followed-up. Along with standard therapy, all patients received systemic and local ozone therapy. Read More

Urologiia 2018 Dec(6):101-106

Department of Polyclinic Therapy and Medical Rehabilitation with the course of Additional Professional Education Federal State Educational Institution of Higher Education Altai State Medical University of the Ministry of Health of the Russian Federation, Barnaul, Russia.

The aim of the study was to increase the efficiency of complex treatment of patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) with the combined effect of magnetolaser therapy (MLT) and red light.

Materials And Methods: We examined and included in the study 120 men with a verified diagnosis of CP/CPPS (III B), at the stage of exacerbation. By envelope method, patients were divided into two randomized groups. Read More

Eur J Pain 2019 Feb 8. Epub 2019 Feb 8.

Department of Neurology, Leiden University Medical Centre, Leiden, The Netherlands.

Background: Complex regional pain syndrome (CRPS) is much more prevalent in women than men but potential differences in clinical phenotype have not been thoroughly explored to date. Differences in the clinical presentation between sexes may point at new avenues for a more tailored management approach of CRPS. We therefore explored if in CRPS, the patient's sex is associated with differences in clinical and psychological characteristics. Read More

J Hand Surg Am 2019 Feb 4. Epub 2019 Feb 4.

Department of Orthopaedic Surgery, Southern California Permanente Medical Group, Anaheim, CA. Electronic address:

Purpose: Osteotomy of the distal radius for a fracture malunion is a challenging procedure. The purpose of this study was to review a series of osteotomies to determine the type and risk of complications.

Methods: A retrospective cohort study was performed, including all Kaiser Permanente Southern California patients who were aged 18 years or older between January 1, 2007, and September 25, 2015, and underwent osteotomy for an extra-articular distal radius fracture malunion. Read More