Clin Microbiol Infect 2022 May 28. Epub 2022 May 28.
Section of Pediatrics, Department of Health Sciences, University of Florence, Viale Gaetano Pieraccini 24, 50139, Florence, Italy; Immunology and Molecular Microbiology Unit, Meyer Children's Hospital, Viale Gaetano Pieraccini 24, 50139, Florence, Italy.
Background: Pyogenic bacteria are associated with a wide range of clinical manifestation ranging from common and relatively mild respiratory and cutaneous infections to life-threatening localized or systemic infections, such as sepsis and profound abscesses. Despite vaccination and widespread use of effective antibiotic treatment, severe infection is still observed in a subset of affected patients.
Sources: Case series, review and original articles on human genetic susceptibility to pyogenic infections have been examined. Read More