6,056 results match your criteria Compendium of Continuing Education in Dentistry [Journal]


Kinetics of Ligand-Protein Dissociation from All-Atom Simulations: Are We There Yet?

Biochemistry 2018 Dec 14. Epub 2018 Dec 14.

Large parallel gains in the development of both computational resources as well as sampling methods have now made it possible to simulate dissociation events in ligand-protein complexes with all--atom resolution. Such encouraging progress, together with the inherent spatiotemporal resolution associated with molecular simulations, has left their use for investigating dissociation processes brimming with potential, both in rational drug design, where it can be an invaluable tool for determining the mechanistic driving forces behind dissociation rate constants, as well as in force-field development, where it can provide a catalog of transient molecular structures on which to refine force-fields. Although much progress has been made in making force-fields more accurate, reducing their error for transient structures along a transition path could yet prove to be a critical development helping to make kinetic predictions much more accurate. Read More

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December 2018

A Compendium of Intralesional Therapies in Nail Disorders.

Indian Dermatol Online J 2018 Nov-Dec;9(6):373-382

Department of Dermatology and STD, VMMC and Safdarjung Hospital, New Delhi, India.

Nail unit is a complex skin appendage offering natural barrier to drug penetration by virtue of its unique anatomy. This is the reason why topical as well as oral therapies can be largely ineffective when dealing with nail diseases. Intralesional (injectable therapies) offer a practical solution in this scenario. Read More

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December 2018
2 Reads

Deciphering human ribonucleoprotein regulatory networks.

Nucleic Acids Res 2018 Dec 5. Epub 2018 Dec 5.

Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine, Berlin, Germany.

RNA-binding proteins (RBPs) control and coordinate each stage in the life cycle of RNAs. Although in vivo binding sites of RBPs can now be determined genome-wide, most studies typically focused on individual RBPs. Here, we examined a large compendium of 114 high-quality transcriptome-wide in vivo RBP-RNA cross-linking interaction datasets generated by the same protocol in the same cell line and representing 64 distinct RBPs. Read More

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December 2018
2 Reads

Control over Near-Ballistic Electron Transport through Formation of Parallel Pathways in a Single-Molecule Wire.

J Am Chem Soc 2018 Dec 5. Epub 2018 Dec 5.

This paper reports highly efficient coherent tunneling in single-molecule wires of oligo-ferrocenes with one to three Fc units. The Fc units were directly coupled to the electrodes, i.e. Read More

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December 2018
1 Read

SCOPe: classification of large macromolecular structures in the structural classification of proteins-extended database.

Nucleic Acids Res 2018 Nov 30. Epub 2018 Nov 30.

Environmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.

The SCOPe (Structural Classification of Proteins-extended, https://scop.berkeley.edu) database hierarchically classifies domains from the majority of proteins of known structure according to their structural and evolutionary relationships. Read More

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November 2018

Successful Smoking Cessation Associated with Walking Behavior In Patients With Claudication.

Ann Vasc Surg 2018 Nov 27. Epub 2018 Nov 27.

Division of Vascular Surgery and Endovascular Therapy, Michael E. DeBakey Department of Surgery, Baylor College of Medicine / Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas 77030. Electronic address:

Introduction: Behavioral economics theories suggest that a preference for delayed benefits promotes positive behavioral change, a concept relevant to both smoking cessation and community-based exercise regimens for claudication. Given the high rate of smoking among older Veterans, we were interested in examining the association between smoking cessation, exercise regimen adherence, and preferences for delayed vs. immediate benefits. Read More

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November 2018

Population Health Management: Coming of Age.

Authors:
Karen Zander

Prof Case Manag 2019 Jan/Feb;24(1):26-38

Karen Zander, MS, RN, CMAC, FAAN, is President and CEO of The Center for Case Management. Her pioneering work with clinical case management and CareMap systems, begun at New England Medical Center Hospitals (Now Tufts Medical Center) in Boston more than 30 years ago, is internationally recognized. Hospitals and Health Networks named her a "Cutting Edge" leader. She is the author of many articles about case management and editor of The New Definition newsletter. Ms Zander has also written several case management texts: (1) Competency Evaluation Tools for Case Management Professionals, (2) Emergency Department Case Management: The Compendium of Best Practices second edition with K. Walsh, and Hospital Case Management Models: Evidence Connecting the Bedside to the Boardroom and a second edition: Case Management Models: Best Practices for Health Systems and ACOs, also from HCPro. Ms Zander holds a BSN from Illinois Wesleyan University, an MS in Psychiatric-Mental Health Nursing from Boston University, postgraduate credits from Massachusetts Institute of Technology, and a Doctorate in Humane Letters (DHL), honoris causa, from Illinois, Wesleyan University. She has been on the Partners Care at Home Patient/Family Advisory Board for 3 years, and has been a cellist in the New Philharmonia Orchestra for over 25 years.

Purpose: Population health is finally catching up with itself. Before it was known as disease management, it began at New England Medical Center in Boston, MA (now Tufts Medical Center), more than 30 years ago.

Implications For Case Management Practice: Take-away ideas: (1) population health management is about segmenting and targeting specific patient populations for interventions that are evidence based; (2) there are currently many examples of population health management; (3) population health management will not work without social workers and nurse navigators/care coordinators working side by side. Read More

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November 2018
1 Read

Twenty classic signs in oral and maxillofacial radiology.

Authors:
Galal Omami

Oral Radiol 2018 Oct 10. Epub 2018 Oct 10.

Department of Oral Health Practice, Division of Oral Medicine, Diagnosis and Radiology, University of Kentucky College of Dentistry, 800 Rose Street, Room MN-320, Lexington, KY, 40536-0297, USA.

Teachers of radiology often employ the use of classic signs to help learners identify the typical appearance of various pathologies. This article is a compendium of simply-described classic signs in oral and maxillofacial radiology, including their use in differential diagnoses. Read More

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October 2018
3 Reads

Model to estimate abdominal wall thickness in children undergoing placement or replacement of gastrostomy devices.

J Pediatr Surg 2018 Sep 13. Epub 2018 Sep 13.

Pediatric Surgery, Children's Hospital Colorado, 13123 E.16th Avenue, Aurora, CO 80045; University of Colorado School of Medicine, 13001 E 17th Pl, Aurora, CO 80045.

Objectives: Abdominal wall thickness (AWT) is a key measurement when placing or replacing low profile gastrostomy devices. This measurement varies, depending on nutritional status and body habitus. We developed a mathematical model to estimate AWT using a compendium of body measurements. Read More

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September 2018

Of Viroids and Prions.

Authors:
Theodor O Diener

Viruses 2018 Nov 23;10(12). Epub 2018 Nov 23.

Department of Molecular Genetics, University of Maryland, College Park, MD 20472, USA.

In 2017, Hadidi et al. edited a voluminous monograph entitled "Viroids and Satellites", in which each known viroid and viroid-like satellite species was described in detail from many perspectives by more than 100 experts from 24 countries. In its 700+ pages, the book is a much needed detailed and reliable compendium of a subject, which, undoubtedly, is still little known by many potential readers. Read More

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November 2018

Intelligently applying Artificial Intelligence in Chemoinformatics.

Curr Top Med Chem 2018 Nov 20. Epub 2018 Nov 20.

Department of Biotechnology, Indian Institute of Technology Roorkee, Roorkee 247667. India.

The intertwining of chemoinformatics with artificial intelligence (AI) has given a tremendous fillip to the field of drug discovery. With the rapid growth of chemical data from high throughput screening and combinatorial synthesis, AI has become an indispensable tool for drug designers to mine chemical information from large compound databases for developing drugs at a much faster rate as never before. The applications of AI have gone beyond bioactivity predictions and have shown promise in addressing diverse problems in drug discovery like de novo molecular design, synthesis prediction and biological image analysis. Read More

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November 2018

E. coli gene regulatory networks are inconsistent with gene expression data.

Nucleic Acids Res 2018 Nov 20. Epub 2018 Nov 20.

Department of Mathematics and Computer Science, University of Southern Denmark, Campusvej 55, 5230 Odense, Denmark.

Gene regulatory networks (GRNs) and gene expression data form a core element of systems biology-based phenotyping. Changes in the expression of transcription factors are commonly believed to have a causal effect on the expression of their targets. Here we evaluated in the best researched model organism, Escherichia coli, the consistency between a GRN and a large gene expression compendium. Read More

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November 2018
8 Reads

Obstructive sleep disordered breathing in children - an important problem in the light of current European guidelines.

Otolaryngol Pol 2018 Jun;72(5):9-16

Medical Center in Ostrołęka, Branch in Różan.

Obstructive sleep-disordered breathing (SDB) is a common clinical problem. An unrecognized and untreated SDB is a serious threat for an intensively developing organism of a child. The consequences of SDB include cardiovascular and neurological complications, growth disorders and enuresis. Read More

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June 2018
5 Reads

Dissecting clinical outcome of porcine circovirus type 2 with in vivo derived transcriptomic signatures of host tissue responses.

BMC Genomics 2018 Nov 20;19(1):831. Epub 2018 Nov 20.

Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.

Background: Porcine Circovirus Type 2 (PCV2) is a pathogen that has the ability to cause often devastating disease manifestations in pig populations with major economic implications. How PCV2 establishes subclinical persistence and why certain individuals progress to lethal lymphoid depletion remain to be elucidated.

Results: Here we present PorSignDB, a gene signature database describing in vivo porcine tissue physiology that we generated from a large compendium of in vivo transcriptional profiles and that we subsequently leveraged for deciphering the distinct physiological states underlying PCV2-affected lymph nodes. Read More

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November 2018
1 Read

Natural language processing-based assessment of consistency in summaries of product characteristics of generic antimicrobials.

Pharmacol Res Perspect 2018 Dec 11;6(6):e00435. Epub 2018 Nov 11.

Department of Medical Informatics Kagawa University Hospital Kagawa Japan.

To investigate consistency in summaries of product characteristics (SmPCs) of generic antimicrobials, we used natural language processing (NLP) to analyze and compare large amounts of text quantifying consistency between original and generic SmPCs. We manually compared each section of generic and original SmPCs for antimicrobials listed in the electronic Medicines Compendium in the United Kingdom, focusing on omissions and additions of clinically significant information (CSI). Independently, we quantified differences between the original and generic SmPCs using Kachako, a fully automatic NLP platform. Read More

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December 2018
2 Reads

Causal Transcription Regulatory Network Inference Using Enhancer Activity as a Causal Anchor.

Int J Mol Sci 2018 Nov 15;19(11). Epub 2018 Nov 15.

Division of Developmental Biology, The Roslin Institute, The University of Edinburgh, Easter Bush, Midlothian, EH25 9RG Scotland, UK.

Transcription control plays a crucial role in establishing a unique gene expression signature for each of the hundreds of mammalian cell types. Though gene expression data have been widely used to infer cellular regulatory networks, existing methods mainly infer correlations rather than causality. We developed statistical models and likelihood-ratio tests to infer causal gene regulatory networks using enhancer RNA (eRNA) expression information as a causal anchor and applied the framework to eRNA and transcript expression data from the FANTOM Consortium. Read More

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November 2018
2 Reads

Assessing progress of the Pan American Health Organization's Policy Research for Health in member states.

Gac Sanit 2018 Nov 12. Epub 2018 Nov 12.

Pan American Health Organization/World Health Organization, Washington, DC, USA.

The improvement of health in the twenty-first century is inextricably linked to research for health. In response to growing international appeal to address regional health needs, the Pan American Health Organization (PAHO) and its Member States approved the Policy on Research for Health (CD49/10) in 2009. This document represents the flagship regional policy on research for health and outlines how health systems and services in the region can be strengthened through research. Read More

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November 2018
3 Reads
1.250 Impact Factor

Emotion Norms, Display Rules, and Regulation in the Akan Society of Ghana: An Exploration Using Proverbs.

Front Psychol 2018 31;9:1916. Epub 2018 Oct 31.

Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Kowloon, Hong Kong.

Proverbs are widely used by the Akan of West Africa. The current study thematically analyzed an Akan proverb compendium for proverbs containing emotion references. Of the identified proverbs, a focus on negative emotions was most typical. Read More

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October 2018
3 Reads

Natural Health Strategies for Pain Care, Part I: A Phytomedicine Compendium.

Holist Nurs Pract 2019 Jan/Feb;33(1):60-65

College of Nursing and Health Professions, Drexel University, Philadelphia, Pennsylvania.

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November 2018
2 Reads

Ceramic Restorations Flourishing With State-of-the-Art Materials, Methods.

Compend Contin Educ Dent 2018 Nov/Dec;39(10):722-723

Associate Professor, Division of General Dentistry, Department of Restorative Sciences, University of Alabama at Birmingham School of Dentistry, Birmingham, Alabama.

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November 2018
6 Reads

No-Preparation Veneers: A Minimally Invasive Approach for a Naturally Esthetic Smile.

Authors:
Zachary S Sisler

Compend Contin Educ Dent 2018 Nov/Dec;39(10):714-720

Associate Faculty, The Dawson Academy, St. Petersburg, Florida; Private Practice, Shippensburg, Pennsylvania.

Typically, dentists spend many years training to learn how to prepare teeth for restorations. Whether the restoration comprises a filling, veneer, crown, inlay, onlay, or bridge, teeth often require preparation to allow adequate space to accommodate the thickness of the restorative material. However, dentists may face a dilemma if a patient inquires about receiving an enhanced smile without tooth preparation. Read More

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November 2018
3 Reads

Measurement of the "Bungee Dip" in Implant Stability Using Resonance Frequency Analysis: Two Case Reports.

Authors:
Paul S Rosen

Compend Contin Educ Dent 2018 Nov/Dec;39(10):706-712

Clinical Professor of Periodontics, University of Maryland Dental School, Baltimore, Maryland; Adjunct Professor, James Cook University, Cairns, Australia; Private Practices, Yardley, Pennsylvania, and New York, New York.

Implant stability is a key consideration when determining the point in time a dental implant should be loaded. Often a change in implant stability is observed as healing progresses from initial mechanical stability to biologic stability, ie, osseointegration, during the bone modeling/remodeling process. This change in stability can be objectively measured using resonance frequency analysis (RFA). Read More

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November 2018

Utilizing Digital Technology to Facilitate Dentofacial Integration.

Authors:
Amanda Seay

Compend Contin Educ Dent 2018 Nov/Dec;39(10):696-704

Private Practice, Mount Pleasant, South Carolina.

As digital technology evolves, an increasing number of tools are becoming available to improve team communication during the treatment planning and provision of restorative dentistry. The esthetic relationships among the face, teeth, and tissue can be analyzed using high-quality photographs, presentation software, and video capture, all critical elements for cases requiring digital dentofacial integration. Video capture communicates maximum lip movement and tooth reveal during speech with precision and ease. Read More

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November 2018
14 Reads

The Need to Replace a Missing Second Molar With a Dental Implant Restoration: Analysis of a Controversial Issue.

Compend Contin Educ Dent 2018 Nov/Dec;39(10):686-693; quiz 694

Clinical Assistant Professor, Department of Prosthodontics, College of Dental Medicine, Columbia University; Private Practice, Surgical Implantology and Prosthodontics, White Plains, New York.

Whether or not a second molar should be replaced after its removal is debatable. To assess the evidence and discuss the pros and cons of replacing a missing second molar with a dental implant restoration, the authors searched the literature for articles that evaluated the following factors: chewing efficiency, tooth loss, super-eruption, extrusion, over-eruption, and occlusal interferences. The data indicated that replacing a second molar provides some increased masticatory performance, but first-molar occlusion facilitates 90% chewing efficiency. Read More

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November 2018

Collaborating With the Perinatal Team for Optimal Oral Health Before, During, and After a Healthy Pregnancy.

Compend Contin Educ Dent 2018 Nov/Dec;39(10):678-684; quiz 685

Assistant Professor, Department of Periodontology, and Faculty Practice Provider, Tufts University School of Dental Medicine, Boston, Massachusetts.

Collaboration with other health professionals can be challenging when attempting to coordinate healthcare before, during, and after pregnancy. However, advantages of interdisciplinary and interprofessional collaborative approaches include facilitation of accurate and timely diagnosis and optimally sequenced treatment for improved health outcomes. This article reviews the current guidelines fostering collaboration between dental professionals and members of the perinatal team and identifies the roles of healthcare providers to support the care of women around the time of pregnancy. Read More

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November 2018
12 Reads

Scan the lung: Point-of-care ultrasound of a pulmonary consolidation with loculated pleural effusion.

Am J Emerg Med 2018 Oct 26. Epub 2018 Oct 26.

Department of Emergency Medicine, Rowan University SOM/Jefferson Health, Stratford, NJ, USA.

Thoracic ultrasound has become an increasingly valuable tool in the evaluation of critically ill patients in the emergency department (ED). The utility of point-of-care ultrasound (POCUS) to identify suspected pneumothorax, pulmonary edema, pleural effusion and pneumonia has been well established (Pagano et al.; Brogi et al. Read More

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October 2018
11 Reads

Magnesium Extravaganza: A Critical Compendium of Current Research into Cellular Mg Transporters Other than TRPM6/7.

Rev Physiol Biochem Pharmacol 2018 Nov 8. Epub 2018 Nov 8.

Biomedical Center Martin, Division of Neurosciences, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovakia.

Magnesium research has boomed within the last 20 years. The real breakthrough came at the start of the new millennium with the discovery of a plethora of possible Mg homeostatic factors that, in particular, included putative Mg transporters. Until that point, Mg research was limited to biochemical and physiological work, as no target molecular entities were known that could be used to explore the molecular biology of Mg homeostasis at the level of the cell, tissue, organ, or organism and to translate such knowledge into the field of clinical medicine and pharmacology. Read More

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November 2018
4 Reads

Improving the Inference of Co-occurrence Networks in the Bovine Rumen Microbiome.

IEEE/ACM Trans Comput Biol Bioinform 2018 Nov 2. Epub 2018 Nov 2.

The importance of the composition and signature of rumen microbial communities has gained increasing attention. One of the key techniques was to infer co-abundance networks through correlation analysis based on relative abundances. In this study, we proposed the use of a framework including a compendium of two correlation measures and three dissimilarity metrics to mitigate the compositional effect in the inference of significant associations in the bovine rumen microbiome. Read More

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November 2018
7 Reads

Vesiclepedia 2019: a compendium of RNA, proteins, lipids and metabolites in extracellular vesicles.

Nucleic Acids Res 2018 Nov 5. Epub 2018 Nov 5.

Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Victoria 3086, Australia.

Extracellular vesicles (EVs) are membranous vesicles that are released by both prokaryotic and eukaryotic cells into the extracellular microenvironment. EVs can be categorised as exosomes, ectosomes or shedding microvesicles and apoptotic bodies based on the mode of biogenesis. EVs contain biologically active cargo of nucleic acids, proteins, lipids and metabolites that can be altered based on the precise state of the cell. Read More

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November 2018
5 Reads
9.112 Impact Factor

Determining Cardiorespiratory Fitness With Precision: Compendium of Findings From the FRIEND Registry.

Prog Cardiovasc Dis 2018 Oct 30. Epub 2018 Oct 30.

Department of Physical Therapy, College of Applied Health Sciences, University of Illinois at Chicago, Chicago, IL, United States of America.

Healthy living (HL) behaviors and characteristics are central to both preventing and treating a myriad of chronic diseases; a key HL characteristic is cardiorespiratory fitness (CRF). Knowing an individual's CRF provides vital information when assessing health status and formulating a plan of care. Normative reference values as well as thresholds that denote varying degrees of health and future risk exist for measures of CRF. Read More

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October 2018

Contemporary psychotherapeutic interventions in patients with anorexia nervosa - a review.

Psychiatr Pol 2018 Aug 24;52(4):663-672. Epub 2018 Aug 24.

Instytut Psychiatrii i Neurologii, Klinika Nerwic, Zaburzeń Osobowości i Odżywiania, Warszawa.

Due to its ego-syntonic nature, anorexia nervosa (AN) is considered one of the most difficult mental disorders to treat. Patients are often reluctant to accept treatment, while a large group of those who receive therapy have a poor prognosis. Unfortunately, despite suffering from physical and psychosocial impairment, patients with AN are often reluctant to receive any intervention whatsoever. Read More

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August 2018
3 Reads

Is the alcohol industry doing well by 'doing good'? Findings from a content analysis of the alcohol industry's actions to reduce harmful drinking.

BMJ Open 2018 Oct 24;8(10):e024325. Epub 2018 Oct 24.

Psychiatry Institute, Columbia University, New York, USA.

Objectives: The aims of this study were to: (1) describe alcohol industry corporate social responsibility (CSR) actions conducted across six global geographic regions; (2) identify the benefits accruing to the industry ('doing well'); and (3) estimate the public health impact of the actions ('doing good').

Setting: Actions from six global geographic regions.

Participants: A web-based compendium of 3551 industry actions, representing the efforts of the alcohol industry to reduce harmful alcohol use, was issued in 2012. Read More

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October 2018
3 Reads

The chromatin accessibility landscape of primary human cancers.

Science 2018 10;362(6413)

We present the genome-wide chromatin accessibility profiles of 410 tumor samples spanning 23 cancer types from The Cancer Genome Atlas (TCGA). We identify 562,709 transposase-accessible DNA elements that substantially extend the compendium of known cis-regulatory elements. Integration of ATAC-seq (the assay for transposase-accessible chromatin using sequencing) with TCGA multi-omic data identifies a large number of putative distal enhancers that distinguish molecular subtypes of cancers, uncovers specific driving transcription factors via protein-DNA footprints, and nominates long-range gene-regulatory interactions in cancer. Read More

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October 2018
8 Reads

Compendium of physical activities strongly underestimates the oxygen cost during activities of daily living in stroke patients.

Am J Phys Med Rehabil 2018 Oct 24. Epub 2018 Oct 24.

HAVAE EA6310 (Handicap, Aging, Autonomy, Environment), University of Limoges, France.

Objective: To measure the Metabolic Equivalent Task (MET) when performing physical activities of daily living in post-stroke individuals.

Design: Post-stroke individuals who were able to walk without human assistance were recruited and asked to perform the following activities of daily living: washing dishes (activity code:05041 in Ainsworth's compendium), walking at a slow pace <2mph (activity code:17151), climbing stairs (activity code: 17133), walking down stairs (activity code:17070). The MET was measured along these activities using a portable breath gas exchange analyzer. Read More

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October 2018

Transcriptional Programming of Normal and Inflamed Human Epidermis at Single-Cell Resolution.

Cell Rep 2018 Oct;25(4):871-883

Department of Dermatology, University of California, San Francisco, San Francisco, CA, USA. Electronic address:

Perturbations in the transcriptional programs specifying epidermal differentiation cause diverse skin pathologies ranging from impaired barrier function to inflammatory skin disease. However, the global scope and organization of this complex cellular program remain undefined. Here we report single-cell RNA sequencing profiles of 92,889 human epidermal cells from 9 normal and 3 inflamed skin samples. Read More

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October 2018
6 Reads

Introduction to Cardiovascular Aging Compendium.

Circ Res 2018 Sep;123(7):737-739

The Salk Institute for Biological Studies, La Jolla, CA (J.C.B.).

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September 2018
7 Reads

Validating Publicly Available Crosswalks for Translating ICD-9 to ICD-10 Diagnosis Codes for Cardiovascular Outcomes Research.

Circ Cardiovasc Qual Outcomes 2018 Oct;11(10):e004782

Section of Vascular Surgery, Dartmouth-Hitchcock Medical Center, Lebanon, NH (J.A.C., P.P.G.).

Background On October 1, 2015, the Center for Medicare and Medicaid Services transitioned from the International Classification of Diseases, Ninth Revision ( ICD-9) to the ICD, Tenth Revision ( ICD-10) compendium of codes for diagnosis and billing in health care, but translation between the two is often inexact. Here we describe a validated crosswalk to translate ICD-9 codes into ICD-10 codes, with a focus on complications after carotid revascularization and endovascular aortic aneurysm repair. Methods and Results We devised an 8-step process to derive and validate ICD-10 codes from existing ICD-9 codes. Read More

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October 2018
13 Reads

Investigation of inter- and intraspecies variation through genome sequencing of Aspergillus section Nigri.

Nat Genet 2018 Dec 22;50(12):1688-1695. Epub 2018 Oct 22.

Department of Biotechnology and Bioengineering, Technical University of Denmark, Kongens Lyngby, Denmark.

Aspergillus section Nigri comprises filamentous fungi relevant to biomedicine, bioenergy, health, and biotechnology. To learn more about what genetically sets these species apart, as well as about potential applications in biotechnology and biomedicine, we sequenced 23 genomes de novo, forming a full genome compendium for the section (26 species), as well as 6 Aspergillus niger isolates. This allowed us to quantify both inter- and intraspecies genomic variation. Read More

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December 2018
11 Reads

Recent progress in non-opioid analgesic peptides.

Arch Biochem Biophys 2018 Dec 17;660:36-52. Epub 2018 Oct 17.

Instituto de Química Médica, IQM-CSIC, Juan de La Cierva 3, 28006, Madrid, Spain. Electronic address:

Pain is a prevalent complex medical problem, characterized by physically debilitating and mentally destabilizing conditions. Current pain therapeutics mainly include non-steroidal anti-inflammatory drugs and narcotics (opioids), but they exhibit limitations in efficacy, unwanted side effects and the problem of drug abuse. To overcome these issues, the discovery of different molecular players within pain pathways could lead to new opportunities for therapeutic intervention. Read More

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December 2018
5 Reads

C3: An R package for cross-species compendium-based cell-type identification.

Comput Biol Chem 2018 Dec 9;77:187-192. Epub 2018 Oct 9.

Victor Chang Cardiac Research Institute, Darlinghurst, NSW, Australia; St. Vincent's Clinical School, University of New South Wales, Sydney, NSW, Australia; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China. Electronic address:

Cell type identification from an unknown sample can often be done by comparing its gene expression profile against a gene expression database containing profiles of a large number of cell-types. This type of compendium-based cell-type identification strategy is particularly successful for human and mouse samples because a large volume of data exists for these organisms. However, such rich data repositories often do not exist for most non-model organisms. Read More

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December 2018
4 Reads
1.120 Impact Factor

Medicinal Materials DNA Barcode Database (MMDBD) version 1.5-one-stop solution for storage, BLAST, alignment and primer design.

Database (Oxford) 2018 01 1;2018. Epub 2018 Jan 1.

Li Dak Sum Yip Yio Chin R&D Centre for Chinese Medicine, The Chinese University of Hong Kong, Hong Kong, China.

Authentication of medicinal materials by deoxyribonucleic acid (DNA) technology is gaining popularity. In 2010, our team has created Medicinal Materials DNA Barcode Database (MMDBD) version 1.0 to provide an interactive database for documenting DNA barcode sequences of medicinal materials. Read More

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January 2018

[A study of the Polish missionary Michel Boym's pharmacy books].

Authors:
L Fu Y Z Xiao

Zhonghua Yi Shi Za Zhi 2018 May;48(3):158-163

China Institute for History of Medicine and Medical Literature, China Academy of Chinese Medical Sciences, Beijing, 100700, China.

Michel Boym was a 17th-century missionary who came to China from Poland. He was the first man who introduce Chinese herbal medicine to Europe by writing () and . This article reveals that which Chinese herbal medicine books may have been consulted in the by analyzing its content and comparing it with the Chinese herbal medicine books. Read More

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Taxonomy of the genus Doryllium Cobb, 1920 (Nematoda: Dorylaimida) with description of two new and a known species.

Zootaxa 2018 Jun 27;4441(2):261-278. Epub 2018 Jun 27.

.

Two new and a known species of the genus Doryllium Cobb, 1920 are described and illustrated. Doryllium enigmatum n. sp. Read More

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June 2018
1 Read

Animal signs in Radiology: method of creating a compendium.

J Med Imaging Radiat Oncol 2018 Oct;62 Suppl 1:7-11

University of New England, Armidale, New South Wales, Australia.

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October 2018
1 Read

[Defining daily doses and total doses for the measurement of antibiotic usage in Swiss pig production].

Schweiz Arch Tierheilkd 2018 Oct;160(10):597-605

Departement für Nutztiere, Abteilung Schweinemedizin, Vetsuisse-Fakultät, Universität Zürich.

Introduction: A significant Antibiotic-Monitoring-System is essential to analyse the use of antibiotics and to a better understanding of trends in resistance development. In human and veterinary medicine, for example, a system based on defined daily and treatment doses (Defined Daily Dose: DDD and Defined Course Dose: DCD) is applied. These definitions can be used to estimate the number of treatment days and treatments with antimicrobial agents in a population. Read More

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October 2018
1 Read

[Online information system for -phytotherapy in animals].

Schweiz Arch Tierheilkd 2018 Oct;160(10):589-595

Institut für Veterinärpharmakologie und -toxikologie, Vetsuisse-Fakultät, Universität Zürich.

Introduction: Phytotherapy becomes increasingly popular in veterinary medicine. To fully exploit the therapeutic potential of medicinal plants and ensure their safe use, knowledge about the effective plant parts and preparations is required. Improper use and overdosage of medicinal plants can be toxic. Read More

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October 2018
1 Read

Dentin Adhesives: Essential Components to Successful Conservative Dentistry.

Authors:
James C Ragain

Compend Contin Educ Dent 2018 Oct;39(9):646-647

Associate Professor and Dean, University of Tennessee Health Science Center College of Dentistry, Memphis, Tennessee.

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October 2018
1 Read

Zygomatic Implants for the Management of Severe Alveolar Atrophy in the Partial or Completely Edentulous Maxilla.

Compend Contin Educ Dent 2018 Oct;39(9):636-645

Private Practice, Oral Surgery, Medellin, Colombia.

Treatment of severely resorbed partially or completely edentulous maxillae can include the utilization of the zygomatic process for immediate implant fixation and stabilization with immediate function. This approach may alleviate the need for significant grafting to enable implant placement in the posterior maxilla and allow implants to be placed into denser, more stable bone. Zygomatic implants, which have been used clinically for the past 20 years in the treatment of the severely resorbed maxilla, allow implant placement to support fixed prosthetics. Read More

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October 2018
4 Reads