10,571 results match your criteria Compartment Syndrome


Lysosomal pH Is Regulated in a Sex Dependent Manner in Immune Cells Expressing .

Front Immunol 2019 2;10:578. Epub 2019 Apr 2.

Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, United States.

and both contain risk alleles for systemic lupus erythematosus (SLE) and Sjögren's syndrome (pSS). The former escapes X inactivation. Our group predicts specific endolysosomal-dependent immune responses are driven by the protein products of these genes, which form a complex at the endolysosomal surface. Read More

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https://www.frontiersin.org/article/10.3389/fimmu.2019.00578
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http://dx.doi.org/10.3389/fimmu.2019.00578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454867PMC
April 2019
1 Read

Management of Pediatric Tibial Shaft Fractures.

J Am Acad Orthop Surg 2019 Apr 16. Epub 2019 Apr 16.

From the University of Texas Health Science Center at San Antonio, San Anotonio, TX.

Diaphyseal tibia fractures in the pediatric population have dynamic treatment strategies that depend on injury pattern, mechanism, patient skeletal maturity and size. Treatment strategies include closed reduction and cast immobilization, flexible nails, uniplanar or multiplanar external fixation or plate osteosynthesis. Accepted parameters for sagittal and coronal alignment vary based on age and potential for remodeling, although all fractures should have minimal rotational malalignment and less than 1 cm of shortening. Read More

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http://dx.doi.org/10.5435/JAAOS-D-17-00819DOI Listing
April 2019
2 Reads

Outcome of inter-hospital transfer of patients on extracorporeal membrane oxygenation in Switzerland.

Swiss Med Wkly 2019 Apr 17;149:w20054. Epub 2019 Apr 17.

Clinic for Cardiovascular Surgery, University Heart Centre, Zurich, Switzerland.

Aims Of The Study: An extracorporeal membrane oxygenation system (ECMO), as a bridge to either recovery, a ventricular assist device (VAD), or heart or lung transplantation, may be the only lifesaving option for critically ill patients suffering from refractory cardiac, respiratory or combined cardiopulmonary failure. As peripheral hospitals may not offer ECMO treatment, tertiary care centres provide specialised ECMO teams for on-site implantation and subsequent patient transfer on ECMO to the tertiary hospital. This study reports the results of the largest ECMO transportation programme in Switzerland and describes its feasibility and safety. Read More

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http://dx.doi.org/10.4414/smw.2019.20054DOI Listing
April 2019
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Chronic lower leg pain: entrapment of common peroneal nerve or tibial nerve.

Unfallchirurg 2019 Apr 16. Epub 2019 Apr 16.

Departments of Surgery, Neurology and Sports Medicine, Maxima Medical Center, De Run 4600, 7777, 5500 MB, Veldhoven, The Netherlands.

Young individuals with chronic exercise-induced lower leg pain (ELP) who have normal compartmental muscle pressures and normal imaging occasionally suffer from a nerve entrapment syndrome. These patients have consistently undergone a variety of diagnostic tests and often futile therapies prior to arriving at the correct diagnosis. Awareness among traumatologists regarding these nerve entities is low. Read More

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http://link.springer.com/10.1007/s00113-019-0645-5
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http://dx.doi.org/10.1007/s00113-019-0645-5DOI Listing
April 2019
2 Reads

Surgical outcomes for chronic exertional compartment syndrome following improved diagnostic criteria.

J R Army Med Corps 2019 Apr 16. Epub 2019 Apr 16.

Academic Department of Military Rehabilitation, Defence Medical Rehabilitation Centre Headley Court, Epsom, UK.

Introduction: Chronic exertional compartment syndrome (CECS) presents with pain during exercise, most commonly within the anterior compartment of the lower limb. A diagnosis is classically made from a typical history and the measurement of intramuscular compartmental pressure (IMCP) testing. Improved, more specific diagnostic criteria for IMCP testing allow clinicians to now be more certain of a diagnosis of CECS. Read More

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http://dx.doi.org/10.1136/jramc-2019-001171DOI Listing
April 2019
1 Read

Bilateral Orbital Compartment Syndrome Preceding Cerebellar Herniation in Neuropsychiatric Systemic Lupus Erythematosus.

Ophthalmic Plast Reconstr Surg 2019 Apr 9. Epub 2019 Apr 9.

Cullen Eye Institute, Baylor College of Medicine, Houston, Texas, U.S.A.

Orbital compartment syndrome poses a significant risk for vision loss if not promptly treated. The authors report a patient with neuropsychiatric systemic lupus erythematosus presenting with bilateral orbital compartment syndrome and rapid decompensation leading to uncal and tonsillar herniation. While extremely rare, bilateral orbital compartment syndrome should prompt consideration of systemic etiologies including neuropsychiatric systemic lupus erythematosus. Read More

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http://dx.doi.org/10.1097/IOP.0000000000001339DOI Listing
April 2019
1 Read

Serial abdominal closure with Gore-tex mesh and Rives-Stoppa for an open abdomen secondary to intra-abdominal hypertension in burns.

Indian J Plast Surg 2018 Sep-Dec;51(3):324-326

St Andrew's Centre for Burns and Plastic Surgery, Broomfield Hospital, Chelmsford, Essex, CM1 7ET, UK.

Intra-abdominal hypertension (IAH) leading to abdominal compartment syndrome (ACS) commonly occurs in major burns. To relieve the excess pressure, decompressive laparotomy is done which can lead to an open abdomen. Closure of the abdomen after a decompressive laparotomy is very difficult with bowel oedema. Read More

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http://dx.doi.org/10.4103/ijps.IJPS_75_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440362PMC
April 2019
1 Read

Epidemiology, treatment and outcome after compartment syndrome of the thigh in 69 cases - Experiences from a level I trauma centre.

Injury 2019 Apr 5. Epub 2019 Apr 5.

Medical University of Vienna, Department of Orthopaedics and Trauma Surgery, Waehringer Guertel 18-20, A-1090, Vienna, Austria. Electronic address:

Background: Compartment syndrome of the thigh (CST) is a rare condition, and its delayed diagnosis and therapy may lead to devastating adverse effects. Thus, the aim of this study was to present the amassed clinical experiences, regarding diagnosis and treatment of CST at a level I trauma centre.

Materials And Methods: The database was reviewed for all patients with a manifest CST treated surgically between 1995 and 2014. Read More

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http://dx.doi.org/10.1016/j.injury.2019.04.001DOI Listing
April 2019
1 Read

Wiskott-Aldrich syndrome protein may be critical for CD8 T cell function following MCMV infection.

Cell Immunol 2019 Apr 27;338:43-50. Epub 2019 Mar 27.

Department of Hematology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. Electronic address:

Wiskott-Aldrich syndrome (WAS) patients are characterized by immunodeficiency and viral infections. T cells derived from WAS patients and WAS protein (WASP)-deficient mice have various defects. However, whether WASP plays a role in immune control of cytomegalovirus (CMV) infection remains unclear. Read More

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http://dx.doi.org/10.1016/j.cellimm.2019.03.004DOI Listing
April 2019
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Chronic exertional compartment syndrome as a cause of anterolateral leg pain.

Unfallchirurg 2019 Apr 12. Epub 2019 Apr 12.

Máxima Medical Center, De Run 4600, P.O. Box 7777, 5500 MB, Veldhoven, The Netherlands.

Exercise-induced leg pain (ELP) and tightness may be caused by a chronic exertional compartment syndrome (CECS). Although CECS can develop in any muscle compartment, most individuals suffer from an anterior tibial muscle CECS (ant-CECS). Typically, a patient with ant-CECS experiences discomfort toward the end of sports activity or in the hours thereafter. Read More

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http://dx.doi.org/10.1007/s00113-019-0641-9DOI Listing
April 2019
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AIRE expression controls the peripheral selection of autoreactive B cells.

Sci Immunol 2019 Apr;4(34)

Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06511, USA.

Autoimmune regulator (AIRE) mutations result in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) syndrome characterized by defective central T cell tolerance and the production of many autoantibodies targeting tissue-specific antigens and cytokines. By studying CD3- and AIRE-deficient patients, we found that lack of either T cells or AIRE function resulted in the peripheral accumulation of autoreactive mature naïve B cells. Proteomic arrays and Biacore affinity measurements revealed that unmutated antibodies expressed by these autoreactive naïve B cells recognized soluble molecules and cytokines including insulin, IL-17A, and IL-17F, which are AIRE-dependent thymic peripheral tissue antigens targeted by autoimmune responses in APECED. Read More

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http://immunology.sciencemag.org/lookup/doi/10.1126/sciimmun
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http://dx.doi.org/10.1126/sciimmunol.aav6778DOI Listing
April 2019
2 Reads

Ischemia-related vascular complications of percutaneously initiated venoarterial extracorporeal membrane oxygenation: Indication setting, risk factors, manifestation and outcome.

J Crit Care 2019 Apr 3;52:58-62. Epub 2019 Apr 3.

Department of Anesthesiology, University Medical Center Regensburg, Franz Josef Strauss Allee 11, 93053 Regensburg, Germany. Electronic address:

Purpose: Venoarterial (VA) ECMO is widely accepted as salvage therapy for cardio-respiratory or cardiac failure. Vascular complications from cannulation are common and potentially life-threatening. Here, we retrospectively analyzed vascular complications following VA ECMO therapy. Read More

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http://dx.doi.org/10.1016/j.jcrc.2019.04.002DOI Listing
April 2019
1 Read

Beware of the Sneeze.

Surv Ophthalmol 2019 Apr 9. Epub 2019 Apr 9.

University of Minnesota Departments of Ophthalmology and Visual Neurosciences and Otolaryngology, University of California, San Diego.

SMARCB1 (SWI/SNF Related Matrix Associated Actin Dependent Regulator Of Chromatin Subfamily B Member 1), also known as integrase interactor 1 (INI1)-deficient sinonasal carcinoma, is a rare entity that was first described in 2014 (1). Since then, there have been 39 cases published in the literature, with basaloid or plasmacytoid/rhabdoid morphology being the most common pathological subtype (2). We report a patient with SMARCB1 (INI-1)-deficient sinonasal carcinoma who had permanent vision loss after valsalva-induced acute hemorrhage and resultant orbital compartment syndrome. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00396257183031
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http://dx.doi.org/10.1016/j.survophthal.2019.04.001DOI Listing
April 2019
2 Reads

Symptomatic Hyperglycemia in a Patient with Dialysis Ascites.

Am J Med Sci 2019 Feb 27. Epub 2019 Feb 27.

Division of Nephrology, Department of Medicine; Research Service, Raymond G. Murphy VA Medical Center, Albuquerque, New Mexico. Electronic address:

An anuric woman with ascites rapidly developed extreme hyperglycemia and seizures after hemodialysis. During development of hyperglycemia, the decrease in serum sodium concentration (Δ[Na]) was nearly twice the value predicted by a formula accounting for the degree of hyperglycemia and the intracellular-to-extracellular volume ratio. The prediction assumed that ascitic fluid is part of the extracellular volume. Read More

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http://dx.doi.org/10.1016/j.amjms.2019.02.016DOI Listing
February 2019
1 Read

Acute compartment syndrome complicating deep venous thrombosis.

N Z Med J 2019 Apr 12;132(1493):73-76. Epub 2019 Apr 12.

Orthopaediac Surgeon, Department of Orthopaedics, Christchurch Hospital, Christchurch.

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April 2019
2 Reads

Bilateral thigh compartment syndromes from extended sitting with forward bending.

J Clin Neurosci 2019 Apr 6. Epub 2019 Apr 6.

Department of Neurology, Juntendo University, Japan.

Alcohol consumption and subsequent sleeping in unusual positions often causes compression neuropathies. In this case, we experienced a unique case of bilateral leg palsy after sleeping in a forward bending position that was photographed by his colleague. We expected that prolonged blockage of the circulation of the femoral arteries resulted in bilateral thigh compartment syndromes (TCSs), leading to sciatic nerve damage. Read More

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http://dx.doi.org/10.1016/j.jocn.2019.03.027DOI Listing
April 2019
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Surgical Tips for Performing Open Fasciotomies for Chronic Exertional Compartment Syndrome of the Leg.

Foot Ankle Int 2019 Apr 9:1071100719842798. Epub 2019 Apr 9.

2 212th Combat Support Hospital, Orthopaedic Surgery Service, Bruchmuhlbach-Miesau, Rhine Ordnance Barracks, Germany.

Chronic exertional compartment syndrome (CECS) of the leg is a debilitating condition that has previously been characterized in athletes and military personnel. The results of surgical management in these patient populations have previously been published with inconsistencies in surgical methods and patient outcomes noted. While endoscopic and minimally invasive techniques have been described, a detailed description of a "standard" open, 2-incision lateral and single-incision medial technique for the treatment of CECS has not been previously published. Read More

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http://dx.doi.org/10.1177/1071100719842798DOI Listing
April 2019
1 Read

Emergency treatment for a venomous snakebite accident in rural southern Mexico.

Rural Remote Health 2019 Apr 10;19(2):4701. Epub 2019 Apr 10.

Ciencias de la Salud y ecología Humana, Av. Independencia Nacional No. 151 Col. Centro CP 48900 Autlan de Jalisco, Mexico

In Latin America, 51 995 emergencies and 337 deaths are caused by snakebites yearly. Prompt and adequate treatment is crucial after an envenomation. We here report the case of a 40-year-old male agriculturalist, who was bitten by a venomous snake. Read More

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http://dx.doi.org/10.22605/RRH4701DOI Listing
April 2019
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Arthroscopic Treatment of Osteochondral Lesions of the Talus in a Suspended Position With the Patient in a Prone Position.

Foot Ankle Int 2019 Apr 8:1071100719839697. Epub 2019 Apr 8.

1 Department of Orthopedic Surgery, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.

Background: The purpose of this study was to evaluate the clinical results and the safety of arthroscopic microfracture with the ankle suspended on a shoulder-holding traction frame for simultaneous anterior and posterior ankle arthroscopy in the prone position.

Methods: Between May 2010 and January 2016, 31 patients with posterior osteochondral lesions of the talus (OLTs) were treated with arthroscopic microfracture in a suspended position with the patient prone. Ankle distraction was achieved by suspending the affected ankle on a shoulder-holding traction frame. Read More

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http://dx.doi.org/10.1177/1071100719839697DOI Listing
April 2019
3 Reads

A comparison of segmented abdominopelvic fluid volumes with conventional CT signs of abdominal compartment syndrome in a trauma population.

Abdom Radiol (NY) 2019 Apr 5. Epub 2019 Apr 5.

R. Adams Cowley Shock Trauma Center, 22 S. Greene Street, Baltimore, MD, 21201, USA.

Purpose: To compare the utility of abdominopelvic fluid volume measurements with established computed tomography signs for refractory post-traumatic abdominal compartment syndrome.

Methods: This retrospective observational cohort study included 64 consecutive adult trauma patients with preoperative CT and diagnosis of refractory abdominal compartment syndrome requiring decompressive laparotomy at a level I trauma referral center between 2004 and 2014. We hypothesized that abdominal fluid volume measurements would be more predictive of the need for early laparotomy than previously described conventional CT signs of refractory ACS. Read More

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http://link.springer.com/10.1007/s00261-019-02000-8
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http://dx.doi.org/10.1007/s00261-019-02000-8DOI Listing
April 2019
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Intraabdominal hypertension/abdominal compartment syndrome after pelvic fractures: How they occur and what can be done?

Injury 2019 Mar 28. Epub 2019 Mar 28.

Department of Orthopedics, Physical Medicine & Rehabilitation, Denver Health Medical Center, University of Colorado, 777 Bannock St, MC 0188, Denver, CO 80204, USA. Electronic address:

Background: Limited data exist regarding intraabdominal hypertension/abdominal compartment syndrome (IAH/ACS) after pelvic fractures. We aimed to explore risk factors for IAH/ACS in pelvic fracture patients, assess the physiological effects of decompressive laparotomy (DL) on IAH/ACS, and generate an algorithm to manage IAH/ACS after pelvic fracture.

Materials And Methods: Pelvic fracture patients were included based on the presence of IAH/ACS. Read More

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http://dx.doi.org/10.1016/j.injury.2019.03.037DOI Listing
March 2019
2 Reads

VCAM1 is Induced in Ovarian Theca and Stromal Cells in a Mouse Model of Androgen Excess.

Endocrinology 2019 Apr 5. Epub 2019 Apr 5.

Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX.

Ovarian theca androgen production is regulated by the pituitary luteinizing hormone (LH) and intra-follicular factors. Enhanced androgen biosynthesis by theca cells contributes to polycystic ovary syndrome (PCOS) in women, but the ovarian consequences of elevated androgens are not completely understood. Our study documents the molecular events that are altered in the theca and stromal cells of mice exposed to high androgen levels, using the non-aromatizable androgen DHT. Read More

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http://dx.doi.org/10.1210/en.2018-00731DOI Listing
April 2019
2 Reads

Negative pressure wound therapy as a definitive treatment for upper extremity wound defects: A systematic review.

Int Wound J 2019 Apr 4. Epub 2019 Apr 4.

Plastic and Reconstructive Surgery Service, Centre Hospitalier de l'Université de Montréal (CHUM), Montréal, Québec, Canada.

Negative pressure wound therapy (NPWT) represents one of the many solutions for complex wounds of the upper extremity. The goal of this study was to investigate the most common indications for definitive treatment of wound defects in the upper extremity with NPWT and to report revision surgery outcomes after its use. A systematic review of the literature was performed. Read More

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http://dx.doi.org/10.1111/iwj.13128DOI Listing

An unusual case of unilateral supernumerary extensor carpi radialis muscle.

Folia Morphol (Warsz) 2019 Apr 5. Epub 2019 Apr 5.

Pediatric Surgery Clinic of Emergency Children's Hospital, Doctor Iosif Nemoianu 2, 300011 Timisoara, Romania.

An uncommon anatomical variant of muscle was found during the dissection of the forearm region, that can be considered as a supernumerary extensor carpi radialis muscle. The identified extensor carpi radialis muscle has origin on the lateral supraepicondylar ridge of the humerus, and an unusual insertion on the tubercle of the scaphoid bone. The presence of this supernumerary muscle may cause diagnostic errors in the forearm region, and can produce a debilitating pain syndrome by secondary compression of adjacent nerves, vessels or tendons due to its course along the anterior compartment of the forearm. Read More

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http://dx.doi.org/10.5603/FM.a2019.0037DOI Listing
April 2019
2 Reads

Compartment Syndrome following Snakebite Leads to Decompressive Fasciotomies.

Case Rep Med 2019 4;2019:6324569. Epub 2019 Mar 4.

Department of Public Health and Forensic Sciences, and Medical Education, Faculty of Medicine, University of Porto, Porto, Portugal.

Snakebite envenoming is a neglected tropical disease with relevant morbidity and mortality. In this report, we illustrate the clinical course of a suspected snakebite envenoming of a patient that evidenced severe pain, edema, pallor, regional lymphadenopathy, ecchymosis, myonecrosis, and bullous erythema in the right lower limb, specially around the fang marks. The clinical course progressed to compartment syndrome followed with decompressive fasciotomies to reduce pressure within the affected compartment. Read More

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http://dx.doi.org/10.1155/2019/6324569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425384PMC
March 2019
2 Reads

A Minimally Invasive Technique for the 1-Stage Treatment of Complex Pelvic Floor Diseases: Laparoscopic-Pelvic Organ Prolapse Suspension.

Female Pelvic Med Reconstr Surg 2019 Apr 3. Epub 2019 Apr 3.

Ospedale Maggiore Policlinico, Fondazione IRCCS Ca' Granda, Milano, Department of Pathophysiology and Transplantation, University of Milano, Milano, Italy.

Objective: The aim of this prospective study was to assess the safety and effectiveness of a new single laparoscopic operation devised to relieve obstructed defecation, gynecologic and urinary symptoms in a large series of female patients with multiorgan pelvic prolapse.

Methods: We submitted 384 female patients to laparoscopic pelvic organ prolapse suspension operation, a new technique based on suspension of the middle pelvic compartment, by using a polypropylene mesh and followed up 368 of them, with defecography performed 12 months after surgery and a standardized protocol.

Results: The 368 patients were followed-up for 36. Read More

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http://dx.doi.org/10.1097/SPV.0000000000000722DOI Listing
April 2019
3 Reads

Retrobulbar Orbital Emphysema Associated with Medial Orbital Wall Fracture.

J Craniofac Surg 2019 Mar 28. Epub 2019 Mar 28.

Department of Oral and Maxillofacial Surgery, Shimane University Faculty of Medicine.

Retrobulbar emphysema is a rare condition compared to the more common orbital emphysema. It is often associated with medial orbital wall fracture with rupture of the periosteum. In some severe patients, retrobulbar emphysema can increase the intraorbital pressure and lead to orbital compartment syndrome. Read More

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http://dx.doi.org/10.1097/SCS.0000000000005390DOI Listing
March 2019
6 Reads

The role of stroma and epithelial cells in primary Sjögren's syndrome.

Rheumatology (Oxford) 2019 Mar 3. Epub 2019 Mar 3.

Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK.

Primary SS (pSS) is a chronic autoimmune condition characterized by infiltration of the exocrine glands and systemic B cell hyperactivation. This glandular infiltration is associated with loss of glandular function, with pSS patients primarily presenting with severe dryness of the eyes and mouth. Within the affected glands, the infiltrating lymphocytes are organized in tertiary lymphoid structures. Read More

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http://dx.doi.org/10.1093/rheumatology/kez050DOI Listing
March 2019
2 Reads

Principles of safety for ultrasound-guided single injection blocks in the emergency department.

Am J Emerg Med 2019 Mar 27. Epub 2019 Mar 27.

Alameda Health System/Highland General Hospital, Department of Emergency Medicine, United States of America.

Ultrasound-guided nerve blocks (UGNBs) allow emergency physicians an opportunity to provide optimal pain management for acute traumatic conditions. Over the past decade, a growing body of literature has detailed the novel ways clinicians have incorporated UGNBs for analgesia and an alternative to procedural sedation. UGNBs are considered a relatively safe procedure, and have been shown to increase rates of success and reduce complications (as compared to older techniques). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07356757193019
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http://dx.doi.org/10.1016/j.ajem.2019.03.045DOI Listing
March 2019
4 Reads

Bilateral simultaneous chronic exertional compartment syndrome of the lateral forefoot: A case report (compartment syndrome of the forefoot).

J Orthop Surg (Hong Kong) 2019 May-Aug;27(2):2309499019839647

1 Service d'Orthopédie-Traumatologie, Hôpital Gabriel Montpied, CHU de Clermont Ferrand BP 69, Clermont Ferrand, France.

A 20-year-old patient came to the sport medicine clinic for bilateral forefoot pain during sport activities (running) progressing for the last 3 months. Thanks to a positive measurement of the compartment pressure during a running test reproducing the symptomatology and exclusion of classical differential diagnosis, a bilateral chronic compartment syndrome of the lateral forefoot was confirmed. Three months after a surgical fasciotomy, the patient fully recovered. Read More

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http://dx.doi.org/10.1177/2309499019839647DOI Listing
April 2019
2 Reads

Non-invasive Diagnostics for Extremity Compartment Syndrome following Traumatic Injury: A State of the Art Review.

J Trauma Acute Care Surg 2019 Apr 1. Epub 2019 Apr 1.

US Army Institute of Surgical Research, Fort Sam Houston, TX.

Acute compartment syndrome (ACS) is a serious medical condition that can occur following traumatic injury to an extremity. If left undiagnosed, ACS can eventuate in amputation of the limb or even death. Because of this, fasciotomy to release the pressure within the muscle and restore tissue perfusion is often performed upon suspicion of ACS, as the sequelae to fasciotomy are less severe than those associated with not performing the fasciotomy. Read More

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http://dx.doi.org/10.1097/TA.0000000000002284DOI Listing
April 2019
5 Reads

Cyclosporin population pharmacokinetics in pediatric refractory nephrotic syndrome based on real-world studies: Effects of body weight and spirolactone administration.

Exp Ther Med 2019 Apr 27;17(4):3015-3020. Epub 2019 Feb 27.

Department of Pharmacy, Children's Hospital of Fudan University, Shanghai 201102, P.R. China.

Different models of population pharmacokinetics (PPK) of cyclosporin have been established in various populations. However, the cyclosporin PPK model in patients with pediatric refractory nephrotic syndrome (PRNS) has yet to be constructed. The present study aimed to establish the cyclosporin PPK model in PRNS, and to identify factors that may account for any variability. Read More

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http://dx.doi.org/10.3892/etm.2019.7325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434233PMC
April 2019
1 Read

The plantaris muscle: too important to be forgotten. A review of evolution, anatomy, clinical implications and biomechanical properties.

J Sports Med Phys Fitness 2019 May;59(5):839-845

Department of Orthopedic Surgery, University Hospital Center Zagreb, School of Medicine, University of Zagreb, Zagreb, Croatia -

Plantaris muscle (lat. musculus plantaris) is a fusiform muscle of the superficial posterior leg compartment, characterized with a small muscle belly and very long and slender tendon. Many anatomical variations of plantaris muscle have been reported previously, including its inconstancy. Read More

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http://dx.doi.org/10.23736/S0022-4707.18.08816-3DOI Listing
May 2019
2 Reads

Compartment syndrome of the hand after laparoscopic gynecological surgery.

J Minim Invasive Gynecol 2019 Mar 29. Epub 2019 Mar 29.

Department of Gynecologic Oncology, Instituto Nacional de Cancerologia, Bogota, D.C., Colombia. Electronic address:

Acute compartment syndrome (ACS) of the hand is a potentially devastating and infrequent condition observed after trauma, arterial injury, or after prolonged compression of the upper limb. We present the case of a patient diagnosed with compartment syndrome of the hand after laparoscopic surgery for an epithelial ovarian cancer. Is a 42-year-old woman with incidental finding of high-grade ovarian serous carcinoma after an emergency surgery. Read More

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http://dx.doi.org/10.1016/j.jmig.2019.03.017DOI Listing
March 2019
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An Acute Paraspinal Compartment Syndrome: Anatomic Description of the Compartment and Surgical Technique.

Clin Spine Surg 2019 Mar 29. Epub 2019 Mar 29.

Department of Orthopaedic Surgery, University Hospitals Leuven, Pellenberg, Belgium.

An acute paraspinal compartment syndrome (CS) is a rare condition and is only described in a few case reports. In our spine surgery department, a 16-year-old boy with severe low back pain due to a lumbar paraspinal CS. was treated with a paraspinal fasciotomy. Read More

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http://dx.doi.org/10.1097/BSD.0000000000000824DOI Listing
March 2019
2 Reads

Comparison of Dorsal Dermal Fascial Fenestrations With Fasciotomy in an Acute Compartment Syndrome Model in the Foot.

Foot Ankle Int 2019 Apr 1:1071100719839944. Epub 2019 Apr 1.

1 University of Wisconsin, Department of Orthopedics and Rehabilitation, Madison, WI, USA.

Background:: Treatment of compartment syndrome of the foot with fasciotomy remains controversial because of the theoretical risk of infection and soft tissue coverage issues. The purpose of this study was to evaluate the efficacy of compartment decompression with dorsal dermal fascial fenestration compared with fasciotomy in a cadaveric foot compartment syndrome model. We hypothesized that fasciotomies and dorsal dermal fenestrations would provide equivalent compartment decompression. Read More

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http://dx.doi.org/10.1177/1071100719839944DOI Listing
April 2019
1 Read

Tension hydrocele as an additional cause of acute scrotum: case series and literature review.

Abdom Radiol (NY) 2019 Mar 30. Epub 2019 Mar 30.

Department of Health Sciences (DISSAL), University of Genoa, Emergency Radiology, Policlinico San Martino Hospital, Largo R. Benzi, 10, 16132, Genoa, Italy.

Purpose: To describe the correlation between acute scrotum pain and tension hydrocele, focusing on US and Doppler features.

Methods And Materials: We evaluated retrospectively a series of five patients with a long history of hydrocele who were referred to our institutions for increasing acute scrotal pain. Patients were approached with gray scale US of both testes, as well as with color-Doppler and spectral analysis, comparing the results with those after aspiration and symptoms relief. Read More

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http://dx.doi.org/10.1007/s00261-019-01991-8DOI Listing
March 2019
3 Reads

Implementation and results of a practical grading system for thoracic blunt aortic injury.

J Vasc Surg 2019 Mar 25. Epub 2019 Mar 25.

Division of Vascular Surgery, Department of Surgery, University of Washington, Seattle, Wash.

Objective: We previously proposed a grading system for blunt thoracic aortic injury (BTAI) designed to guide therapy. This study analyzed our outcomes since implementing this system.

Methods: A single-center, retrospective study was conducted of consecutive patients presenting with BTAI between January 2014 and December 2017. Read More

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http://dx.doi.org/10.1016/j.jvs.2019.01.048DOI Listing
March 2019
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Intraperitoneal alloplasty combined with the anterior separation technique in giant incisional hernias.

Pol Przegl Chir 2018 Dec;91(1):1-5

Ukrainian Hernia Society P.L. Shupyk National Medical Academy of Postgraduate Education, Department of Surgery and Proctology; Ukrainian Center for Surgical Treatment of Abdominal Hernia.

The use of the anterior technique for abdominal wall components separation combined with "onlay" alloplasty (ACST + onlay) in giant incisional hernias (IH) may pose a surgical challenge as it does not exclude increased intra-abdominal pressure (IAP) and the occurrence of abdominal compartment syndrome (ACS). There remains a high incidence of surgical site complications. In our view, the use of intra-abdominal alloplasty combined with anterior separation of the anterior abdominal wall components (ACST + IPOM) will contribute to the improvement of surgical outcomes in giant IH. Read More

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http://dx.doi.org/10.5604/01.3001.0012.7798DOI Listing
December 2018
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Experimental study of muscle permeability under various loading conditions.

Biomech Model Mechanobiol 2019 Mar 27. Epub 2019 Mar 27.

Department of Biomedical Engineering, Ben-Gurion University, 8410501, Beer-Sheva, Israel.

The permeability of a few muscle tissues under various loading conditions is characterized. To this end, we develop an experimental apparatus for permeability measurements which is based on the falling head method. We also design a dedicated sample holder which directs the flow through the tissue and simultaneously enables to pre-compress it. Read More

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http://dx.doi.org/10.1007/s10237-019-01138-0DOI Listing
March 2019
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Fluid management as a risk factor for intra-abdominal compartment syndrome in burn patients: A Total Body Surface Area (TBSA) - independent multicenter trial Part I.

J Burn Care Res 2019 Mar 28. Epub 2019 Mar 28.

Dpt. of Hand, Plastic and Reconstructive Surgery, Microsurgery, Burn Center, BG Trauma Center Ludwigshafen, University of Heidelberg, Germany.

Fluid management is one of the anticipated risk factors for intra-abdominal compartment syndrome (ACS). Since fluid requirements depend on the burned total body surface area (TBSA), an independent analysis is necessary to adapt resuscitation protocols and prevent this life-threatening complication. A retrospective multicenter study with matched-pair analysis was conducted in four German burn centers including 38 burn patients with ACS who underwent decompressive laparotomy. Read More

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http://dx.doi.org/10.1093/jbcr/irz053DOI Listing
March 2019
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Ischemic priapism as a model of exhausted metabolism.

Physiol Rep 2019 Mar;7(6):e13999

Department of Critical Care, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.

In vivo metabolic studies typically concern complex open systems. However, a closed system allows better assessment of the metabolic limits. Ischemic priapism (IP) constitutes a special model of the compartment syndrome that allows direct sampling from a relatively large blood compartment formed by the corpora cavernosa (CC). Read More

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http://dx.doi.org/10.14814/phy2.13999DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436141PMC
March 2019
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The significance of intra-abdominal pressure in neurosurgery and neurological diseases: a narrative review and a conceptual proposal.

Acta Neurochir (Wien) 2019 Mar 25. Epub 2019 Mar 25.

Department of Critical Care Medicine, Ghent University Hospital, Ghent, Belgium.

Intra-abdominal pressure (IAP) is a physiological parameter that has gained considerable attention during the last few decades. The incidence of complications arising from increased IAP, known as intra-abdominal hypertension (IAH) or abdominal compartment syndrome in critically ill patients, is high and its impact is significant. The effects of IAP in neurological conditions and during surgical procedures are largely unexplored. Read More

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http://link.springer.com/10.1007/s00701-019-03868-7
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http://dx.doi.org/10.1007/s00701-019-03868-7DOI Listing
March 2019
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A Case Report of A Drop Foot Developed After Common Femoral Artery Cannulation for Venoarterial Extracorporeal Membrane Oxygenation.

Noro Psikiyatr Ars 2019 Mar 20;56(1):75-78. Epub 2018 Apr 20.

Department of Chest Surgery, Memorial Hospital, İstanbul, Turkey.

The drop foot cases that are associated with developing neuropathies as a result of acute compartment syndrome or femoral artery ischemia after having cannulation for venoarterial extracorporeal membrane oxygenation (VA-ECMO) have been reported rarely in literature. In this case report, female patients who are 21 years old and developed drop foot depending on ECMO during the process of lung transplantation will be presented as both to be one of the rare neurological complications connected to ECMO and its possible causes will be analyzed. Read More

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http://dx.doi.org/10.5152/npa.2017.19340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427086PMC
March 2019
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Fasciotomy Improvement Through Recognition of Errors Course: A Focused Needs Assessment for Error Management Training for Lower Extremity Fasciotomy Performance.

J Surg Educ 2019 Mar 23. Epub 2019 Mar 23.

Department of Surgery, Walter Reed National Military Medical Center/Uniformed Services University of the Health Sciences, Bethesda, Maryland.

Background: Many injuries from recent wars involve extremity trauma secondary to blasts, which predispose patients to developing extremity compartment syndrome. In military studies, 17% of fasciotomies required revision on arrival to a Role 4 hospital, and 41% of these had missed compartments, which is similar to that seen in civilian centers. While training has decreased this rate to 8%, this number is still too high. Read More

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http://dx.doi.org/10.1016/j.jsurg.2019.03.003DOI Listing
March 2019
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Challenges in the management of floating knee injuries: Results of treatment and outcomes of 224 consecutive cases in 10 years.

Injury 2019 Mar 19. Epub 2019 Mar 19.

Department of Orthopedics and Traumatology, Vito Fazzi Hospital, Lecce, Italy. Electronic address:

Introduction: Floating knee is a flail knee joint resulting from fractures of the shafts or adjacent metaphyses of the femur and the ipsilateral tibia. It is usually associated with several complications and mortality. This study was designed to present our experience with the treatment of this injury. Read More

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http://dx.doi.org/10.1016/j.injury.2019.03.016DOI Listing
March 2019
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