1,074 results match your criteria Comparison of Revascularization Procedures in Coronary Artery Disease


Biodegradable polymer versus second-generation durable polymer drug-eluting stents in patients with coronary artery disease: A meta-analysis.

Health Sci Rep 2018 Nov 5;1(11):e93. Epub 2018 Oct 5.

Sydney Medical School The University of Sydney Camperdown Australia.

Aims: Biodegradable polymer drug-eluting stents (BP-DES) were developed in hopes of reducing the risk of stent thrombosis. The comparison of this new stent platform with second-generation durable polymer drug-eluting stents (DP-DES) has not been well described. We, therefore, performed a meta-analysis to evaluate the safety and efficacy profiles of BP-DES versus second-generation DP-DES in patients with coronary artery disease. Read More

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http://doi.wiley.com/10.1002/hsr2.93
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http://dx.doi.org/10.1002/hsr2.93DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242365PMC
November 2018
2 Reads

Analysis of the ROADSTER pivotal and extended-access cohorts shows excellent 1-year durability of transcarotid stenting with dynamic flow reversal.

J Vasc Surg 2019 Jan 2. Epub 2019 Jan 2.

Division of Vascular and Endovascular Surgery, St. Elizabeth's Hospital, Boston, Mass.

Objective: We report the 1-year outcomes of the Safety and Efficacy Study for Reverse Flow Used During Carotid Artery Stenting Procedure (ROADSTER) multicenter trial. This trial introduced a novel transcarotid neuroprotection system (NPS), the ENROUTE transcarotid NPS (Silk Road Medical Inc, Sunnyvale, Calif). Postoperative results demonstrated that the use of the ENROUTE transcarotid NPS is safe and effective. Read More

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http://dx.doi.org/10.1016/j.jvs.2018.08.179DOI Listing
January 2019
2 Reads

Ten-Year Clinical Outcomes From a Trial of Three Limus-Eluting Stents With Different Polymer Coatings in Patients With Coronary Artery Disease.

Circulation 2019 Jan;139(3):325-333

Deutsches Herzzentrum München, Technische Universität München, Munich (S.K., M.J., A.T., K.M., S.C., H.S., A.K., R.A.B.).

Background: New-generation drug-eluting stents offer the potential for enhanced late outcomes in comparison with early generation drug-eluting stents. However, assessment of extended long-term outcomes for these devices is lacking, especially regarding the comparison between new-generation drug-eluting stents with biodegradable or permanent polymers. The aim of this study is to compare the efficacy and safety of biodegradable polymer-based sirolimus-eluting stents (BP-SES; Yukon Choice PC) versus permanent polymer-based everolimus-eluting stents (PP-EES; Xience) versus early generation permanent polymer-based sirolimus-eluting stents (PP-SES; Cypher) at 10-year follow-up. Read More

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.038065DOI Listing
January 2019
1 Read

Polymer-free versus durable polymer drug-eluting stents in patients with coronary artery disease: A meta-analysis.

Ann Med Surg (Lond) 2019 Feb 11;38:13-21. Epub 2018 Dec 11.

Sydney Medical School, The University of Sydney, Camperdown, Australia.

Background: Polymer-free drug-eluting stents (PF-DES) were introduced with the aim of reducing the risk of stent thrombosis associated with durable polymer drug-eluting stents (DP-DES). The comparison of safety and efficacy profiles between these two stent platforms remains unclear.

Materials And Methods: We conducted electronic database searches for randomized controlled trials (RCTs) comparing patients treated with either PF-DES or DP-DES. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S20490801183027
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http://dx.doi.org/10.1016/j.amsu.2018.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302254PMC
February 2019
4 Reads

SYNTAX Score in Patients With Diabetes Undergoing Coronary Revascularization in the FREEDOM Trial.

J Am Coll Cardiol 2018 Dec;72(23 Pt A):2826-2837

Icahn School of Medicine at Mount Sinai, New York, New York; Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain.

Background: Diabetes mellitus (DM) is associated with complex coronary artery disease (CAD), which in turn results in increased morbidity and mortality from cardiovascular disease.

Objectives: This study sought to evaluate the utility of SYNTAX score (SS) for predicting future cardiovascular events in patients with DM and complex CAD undergoing either coronary artery bypass grafting (CABG) or percutaneous coronary intervention (PCI).

Methods: The FREEDOM (Future REvascularization Evaluation in patients with Diabetes mellitus: Optimal management of Multivessel disease) trial randomized patients with DM and multivessel CAD to undergo either PCI with drug-eluting stents or CABG. Read More

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http://dx.doi.org/10.1016/j.jacc.2018.09.046DOI Listing
December 2018
1 Read

Comparison between radial and femoral access for percutaneous coronary intervention in left main coronary artery disease: a meta-analysis of nonrandomized trials.

Authors:
Yicong Ye Yong Zeng

Coron Artery Dis 2018 Dec 6. Epub 2018 Dec 6.

Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.

Background: To determine whether transradial access (TRA) is as safe and efficacious as transfemoral access (TFA) in patients undergoing left main percutaneous coronary intervention (PCI).

Patients And Methods: A systematic search of Medline, Embase, and the Cochrane Central Register of Controlled Trials databases was performed to indentify studies comparing TRA with TFA in left main PCI. The primary efficacy outcome was the incidence of major adverse cardiac events (MACEs) and the primary safety outcome was bleeding. Read More

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http://dx.doi.org/10.1097/MCA.0000000000000685DOI Listing
December 2018

Comparison of Resolute zotarolimus-eluting and Xience everolimus-eluting stents in patients with de novo long coronary artery lesions: a randomized LONG-DES VI trial.

Coron Artery Dis 2019 Jan;30(1):59-66

Asan Medical Center, Heart Institute, University of Ulsan College of Medicine.

Background: Outcomes for stent-based coronary intervention of lesions with long diseased segments remain relatively unfavorable. This study sought to compare the efficacy of Resolute zotarolimus-eluting stents (R-ZES) and Xience everolimus-eluting stents (EES) for very long coronary lesions.

Methods And Results: This randomized, multicenter, prospective trial compared the use of R-ZES with EES for very long (≥50 mm) native coronary lesions. Read More

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http://dx.doi.org/10.1097/MCA.0000000000000680DOI Listing
January 2019
5 Reads

Comparison of minimally invasive direct coronary artery bypass and drug-eluting stents for management of isolated left anterior descending artery disease: a systematic review and meta-analysis of 7,710 patients.

Ann Cardiothorac Surg 2018 Sep;7(5):567-576

Department of Cardiac Surgery, St. George's Hospital, London, UK.

Background: In the contemporary era of drug-eluting stents (DES) the issue of optimal revascularization strategy for patients with isolated disease of the left anterior descending (LAD) artery has gained more significance. We aimed to evaluate the current best evidence on the subject by performing a systematic review and meta-analysis of the studies comparing minimally invasive direct coronary artery bypass (MIDCAB) grafting with DES in patients with isolated LAD disease.

Methods: A literature search was conducted from 1966 through March 2018 using MEDLINE, EMBASE, and other scientific databases to identify relevant articles. Read More

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http://dx.doi.org/10.21037/acs.2018.06.16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219941PMC
September 2018
2 Reads

Comparison of interventional and surgical myocardial revascularization in kidney transplant recipients - A single-centre retrospective analysis.

Int J Cardiol Heart Vasc 2018 Dec 4;21:96-102. Epub 2018 Nov 4.

Department of Internal Medicine III, Division of Cardiology and Nephrology, University Hospital Frankfurt, Goethe University, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany.

Background: Kidney transplant recipients (KTR) reflect a high-risk population for coronary artery disease (CAD). CAD is the most common cause for morbidity and mortality in this population. However, only few data are available on the favourable revascularization strategy for these patients as they were often excluded from studies and not mentioned in guidelines. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S23529067183011
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http://dx.doi.org/10.1016/j.ijcha.2018.10.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224329PMC
December 2018
5 Reads

Comparison of coronary revascularization appropriateness for non-acute coronary syndrome cases under the 2017 update vs the 2012 appropriate use criteria.

Catheter Cardiovasc Interv 2018 Oct 2. Epub 2018 Oct 2.

MedStar Heart and Vascular Institute, MedStar Washington Hospital Center, Washington, District of Columbia.

Objectives: To compare coronary revascularization appropriateness for non-acute coronary syndrome cases under the 2017 update vs the 2012 appropriate use criteria (AUC).

Background: In 2017, the 2012 AUC for coronary revascularization were updated. We examined how applying these new 2017 updates to our previous inappropriate cases would change their appropriateness. Read More

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http://dx.doi.org/10.1002/ccd.27895DOI Listing
October 2018
2 Reads

10-Year Outcomes of Stents Versus Coronary Artery Bypass Grafting for Left Main Coronary Artery Disease.

J Am Coll Cardiol 2018 Dec 24;72(23 Pt A):2813-2822. Epub 2018 Sep 24.

Department of Cardiology, Center for Medical Research and Information, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. Electronic address:

Background: Comparative outcomes of coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) for left main coronary artery (LMCA) disease were previously reported. However, data on very long-term (>10 years) outcomes are limited.

Objectives: The authors compare 10-year outcomes after PCI and CABG for LMCA disease. Read More

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http://dx.doi.org/10.1016/j.jacc.2018.09.012DOI Listing
December 2018
1 Read

Comparison of International Guidelines for Assessment of Suspected Stable Angina: Insights From the PROMISE and SCOT-HEART.

JACC Cardiovasc Imaging 2018 Sep;11(9):1301-1310

Division of Cardiology, University of British Columbia, Vancouver, British Columbia, Canada.

Objectives: This study sought to compare the performance of major guidelines for the assessment of stable chest pain including risk-based (American College of Cardiology/American Heart Association and European Society of Cardiology) and symptom-focused (National Institute for Health and Care Excellence) strategies.

Background: Although noninvasive testing is not recommended in low-risk individuals with stable chest pain, guidelines recommend differing approaches to defining low-risk patients.

Methods: Patient-level data were obtained from the PROMISE (Prospective Multicenter Imaging Study for Evaluation of Chest Pain) and SCOT-HEART (Scottish Computed Tomography of the Heart) trials. Read More

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http://dx.doi.org/10.1016/j.jcmg.2018.06.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130226PMC
September 2018
2 Reads

Off-pump versus on-pump complete coronary artery bypass grafting: Comparison of the effects on the renal damage in patients with renal dysfunction.

Medicine (Baltimore) 2018 Aug;97(35):e12146

Department of Cardiovascular Surgery, Atatürk University, Erzurum.

Background: We aimed to compare off-pump technique with on-pump technique on renal function in patients with nondialysis-dependent renal dysfunction who underwent coronary artery bypass grafting.

Methods: The 94 patients with renal dysfunction undergoing isolated coronary artery bypass grafting were retrospectively analyzed. No patient was receiving dialysis. Read More

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http://dx.doi.org/10.1097/MD.0000000000012146DOI Listing
August 2018
1 Read

The Comparison of Clinical Outcomes After Drug-Eluting Balloon and Drug-Eluting Stent Use for Left Main Bifurcation In-Stent Restenosis.

Int Heart J 2018 Sep 11;59(5):935-940. Epub 2018 Aug 11.

Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine.

Increasing evidence is available for the use of percutaneous coronary intervention (PCI) in selected patients with unprotected left main (LM) bifurcation coronary lesions. However, little data have been reported on recurrent in-stent restenosis (ISR) for LM bifurcation lesions. The aim of this study was to evaluate the efficacy of a drug-eluting balloon (DEB) for LM bifurcation ISR compared with that of a drug-eluting stent (DES). Read More

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http://dx.doi.org/10.1536/ihj.17-540DOI Listing
September 2018
1 Read
1.130 Impact Factor

Comparison of long-term clinical outcomes between revascularization versus medical treatment in patients with silent myocardial ischemia.

Int J Cardiol 2018 Aug 3. Epub 2018 Aug 3.

Cardiovascular Imaging Center, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea; Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, Rochester, MN, USA.

Background: There have been limited and conflicting results regarding the prognostic impact of revascularization treatment on the long-term clinical outcomes of silent ischemia. The current study aimed to determine whether revascularization treatment compared with medical treatment (MT) alone reduces long-term risk of cardiac death of asymptomatic patients with objective evidence of inducible myocardial ischemia.

Methods: A total of 1473 consecutive asymptomatic patients with evidence of inducible myocardial ischemia were selected from a prospective institutional registry. Read More

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http://dx.doi.org/10.1016/j.ijcard.2018.08.006DOI Listing
August 2018
6 Reads

Comparison of the Cost of Drug-Eluting Stents versus Bare Metal Stents in the Treatment of Critical Limb Ischemia in the United States.

Ann Vasc Surg 2018 Aug 6. Epub 2018 Aug 6.

Johns Hopkins Bayview Vascular and Endovascular Clinical Research Center, Baltimore, MD. Electronic address:

Background: Despite significant technical advancement in the last decade, the durability of endovascular management of critical limb ischemia (CLI) remains highly debatable. Drug-eluting stents (DESs) are being popularized for the management of CLI after its precedent success in coronary intervention. Initial reports on the durability of DES are promising. Read More

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http://dx.doi.org/10.1016/j.avsg.2018.05.051DOI Listing
August 2018
3 Reads
1.030 Impact Factor

A Comparison of Transradial and Transfemoral Percutaneous Coronary Intervention in Chinese Women Based on a Propensity Score Analysis.

Korean Circ J 2018 Aug;48(8):719-727

State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Background And Objectives: Over the past decades, transradial approach for percutaneous coronary intervention (PCI) has been increasingly adopted in clinical practice. Women represent a large population who will possibly benefit from PCI, but they are often under-represented in clinical studies. Therefore, the role of TRI in women remains to be further defined. Read More

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http://dx.doi.org/10.4070/kcj.2018.0040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072662PMC
August 2018
3 Reads
1 Citation

The Likert scale is a powerful tool for quality of life assessment among patients after minimally invasive coronary surgery.

Kardiochir Torakochirurgia Pol 2018 Jun 25;15(2):130-134. Epub 2018 Jun 25.

Department of Cardiac Surgery, American Heart of Poland, Bielsko-Biala, Poland.

Introduction: Health-related quality of life (QoL) is an acknowledged index of treatment effectiveness. There are several methods of its evaluation which are predisposed to different risk of bias.

Aim: To investigate the agreement between objective and subjective tools of QoL assessment in patients who underwent endoscopic atraumatic coronary artery bypass (EACAB) grafting. Read More

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http://dx.doi.org/10.5114/kitp.2018.76480DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066680PMC
June 2018
9 Reads

A prospective multicenter randomized all-comers trial to assess the safety and effectiveness of the thin-strut sirolimus-eluting coronary stent SUPRAFLEX: rationale and design of the TALENT trial.

EuroIntervention 2018 Jul 31. Epub 2018 Jul 31.

Department of Cardiology, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.

Aims: To compare the SUPRAFLEX sirolimus-eluting stent (SES) with the XIENCE everolimus-eluting stent (EES) with respect to target lesion failure (TLF) at 12 months in a non-inferiority trial in a "real world" patient population.

Methods And Results: This is a prospective, randomized, 1:1 balanced, controlled, single-blind, multi-center study comparing clinical outcomes at 12 months between SUPRAFLEX and XIENCE in an "all-comers" patient population, comprising a total of 1,430 enrolled subjects with symptomatic coronary artery disease who qualify for percutaneous coronary interventions at 23 centers in Europe. The primary endpoint is a non-inferiority comparison of the device-oriented composite endpoint Target Lesion Failure (cardiac death, target vessel myocardial infarction and clinically-indicated target lesion revascularization) of the SUPRAFLEX group to the XIENCE group at 12 months post-procedure. Read More

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http://dx.doi.org/10.4244/EIJ-D-18-00499DOI Listing
July 2018
10 Reads
3.770 Impact Factor

Coronary computed tomography angiography vs. myocardial single photon emission computed tomography in patients with intermediate risk chest pain: a randomized clinical trial for cost-effectiveness comparison based on real-world cost.

Eur Heart J Cardiovasc Imaging 2018 Jul 23. Epub 2018 Jul 23.

Cardiovascular Center, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Korea.

Aims: To compare the cost-effectiveness of coronary computed tomography angiography (CCTA) vs. myocardial single photon emission computed tomography (SPECT) in patients with stable intermediate risk chest pain.

Methods And Results: Non-acute patients with 10-90% pre-test probability of coronary artery disease from three high-volume centres in Korea (n = 965) were randomized 1:1 to CCTA or myocardial SPECT as the initial non-invasive imaging test. Read More

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http://dx.doi.org/10.1093/ehjci/jey099DOI Listing
July 2018
6 Reads

Stroke Rates Following Surgical Versus Percutaneous Coronary Revascularization.

J Am Coll Cardiol 2018 Jul;72(4):386-398

Department of Cardiothoracic Surgery, Erasmus Medical Center, Rotterdam, the Netherlands.

Background: Coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) are used for coronary revascularization in patients with multivessel and left main coronary artery disease. Stroke is among the most feared complications of revascularization. Due to its infrequency, studies with large numbers of patients are required to detect differences in stroke rates between CABG and PCI. Read More

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http://dx.doi.org/10.1016/j.jacc.2018.04.071DOI Listing
July 2018
9 Reads
16.503 Impact Factor

Comparison of devices used in carotid artery stenting: A vascular quality initiative analysis of commonly used carotid stents and embolic protection devices.

Catheter Cardiovasc Interv 2018 Oct 18;92(4):743-749. Epub 2018 Jul 18.

Division of Cardiovascular Medicine, University of Southern California Keck School of Medicine, Los Angeles, California.

Background: Data regarding efficacy of various stent and embolic protection device (EPD) combinations to prevent stroke during carotid artery stenting (CAS) is limited. We compared post-procedure inpatient neurologic outcomes across various carotid stent-EPD platforms recorded in the Vascular Quality Initiative (VQI) registry.

Methods: We analyzed 13,786 consecutive CAS procedures in the VQI registry performed between January 1, 2005 and December 31, 2015. Read More

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http://dx.doi.org/10.1002/ccd.27646DOI Listing
October 2018
4 Reads

Comparison of outcomes in patients undergoing rotational atherectomy after unsuccessful coronary angioplasty versus elective rotational atherectomy.

Postepy Kardiol Interwencyjnej 2018 19;14(2):128-134. Epub 2018 Jun 19.

Third Department of Cardiology, SMDZ in Zabrze, Silesian Center for Heart Disease, Medical University of Silesia in Katowice, Poland.

Introduction: Revascularization of patients with heavily calcified coronary arteries can be a challenge for interventional cardiologists. The procedural success rate in these patients can be improved by using rotational atherectomy (RA).

Aim: To compare in-hospital outcomes and those at 12-month follow-up between patients who underwent RA as a bailout procedure secondary to failed conventional angioplasty or as an elective procedure. Read More

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http://dx.doi.org/10.5114/aic.2018.76403DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041843PMC
June 2018
6 Reads

Comparing Cardiac Magnetic Resonance-Guided Versus Angiography-Guided Treatment of Patients With Stable Coronary Artery Disease: Results From a Prospective Randomized Controlled Trial.

JACC Cardiovasc Imaging 2018 Jul;11(7):987-996

Heart Clinic Ulm, Ulm Germany.

Objectives: The purpose of this study was the prospective and randomized evaluation of cardiovascular endpoints and quality of life in patients with stable coronary artery disease comparing a cardiac magnetic resonance (CMR)-based management strategy with a coronary angiography-based approach.

Background: Evidence from trials prospectively evaluating the role of CMR in clinical pathways and decision processes is limited.

Methods: Patients with symptomatic CAD were randomized to diagnostic coronary angiography (group 1) or adenosine stress CMR (group 2). Read More

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http://dx.doi.org/10.1016/j.jcmg.2018.05.007DOI Listing
July 2018
11 Reads

Radial Versus Femoral Approach for Percutaneous Coronary Intervention: MACE Outcomes at Long-Term Follow-up.

J Invasive Cardiol 2018 07;30(7):262-268

Hôpital Rangueil, CHU Toulouse, 1 Avenue Jean Poulhès, 31059 Toulouse, France.

Objective: To compare the main outcomes of radial versus femoral access at long-term follow-up.

Background: Little is known about the long-term major cardiovascular events and bleeding complications of patients undergoing percutaneous coronary intervention (PCI) with radial vs femoral approach.

Methods: A total of 1107 patients from the CENTURY II trial were included. Read More

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July 2018
17 Reads

Newer-Generation Ultrathin Strut Drug-Eluting Stents Versus Older Second-Generation Thicker Strut Drug-Eluting Stents for Coronary Artery Disease.

Circulation 2018 Nov;138(20):2216-2226

New York Presbyterian Hospital, Columbia University Medical Center and the Cardiovascular Research Foundation (G.W.S.).

Background: Contemporary second-generation drug-eluting stents (DES) have superior efficacy and safety in comparison with early-generation stents in patients undergoing percutaneous coronary intervention, in part, related to their thinner struts. Whether newer-generation ultrathin DES further improve clinical outcomes in comparison with older second-generation thicker strut DES is unknown.

Methods: We searched PubMed, Embase, and Cochrane Central Register of Controlled Trials for randomized clinical trials that compared newer-generation ultrathin strut DES (defined as strut thickness <70 µm) versus thicker strut second-generation DES and reported clinical outcomes. Read More

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.034456DOI Listing
November 2018

Comparison of the survival between coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with poor left ventricular function (ejection fraction <30%): a propensity-matched analysis.

Eur J Cardiothorac Surg 2018 Jun 22. Epub 2018 Jun 22.

Department of Cardiac Surgery, Bristol Heart Institute, Bristol, UK.

Objectives: Existing evidence comparing the outcomes of coronary artery bypass graft (CABG) surgery versus percutaneous coronary intervention (PCI) in patients with poor left ventricular function (LVF) is sparse and flawed. This is largely due to patients with poor LVF being underrepresented in major research trials and the outdated nature of some studies that do not consider drug-eluting stent PCI.

Methods: Following strict inclusion criteria, 717 patients who underwent revascularization by CABG or PCI between 2002 and 2015 were enrolled. Read More

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http://dx.doi.org/10.1093/ejcts/ezy236DOI Listing
June 2018
9 Reads

Prospective, Randomized Un-Blinded Three Arm Controlled Study in Coronary Artery Revascularization with Minimal Invasive Extracorporeal Circulation Systems (MiECC): Surrogate Parameter Analysis of Biocompatibility.

Heart Surg Forum 2018 05 16;21(3):E179-E186. Epub 2018 May 16.

University Hospital, Department of Thoracic and Cardiovascular Surgery, Frankfurt/Main, Germany.

Objectives: Minimal extracorporeal circulation techniques and systems (MiECC) may reduce the negative side effects of conventional extracorporeal circulation (ECC). However, it is still unclear as to what this is caused by, the reduced priming volume and hemodilution, or the avoidance of blood-air contact and dispersion of mediastinal debris into the systemic circulation. The aim of the trial was the comparison of MiECC to an open ECC setup (openECC) or a system with reduced blood air and debris interaction (closeECC). Read More

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http://dx.doi.org/10.1532/hsf.1946DOI Listing
May 2018
8 Reads

Randomized clinical comparison of the dual-therapy CD34 antibody-covered sirolimus-eluting Combo stent with the sirolimus-eluting Orsiro stent in patients treated with percutaneous coronary intervention: Rationale and study design of the Scandinavian Organization for Randomized Trials with Clinical Outcome (SORT OUT) X trial.

Am Heart J 2018 Aug 5;202:49-53. Epub 2018 May 5.

Department of Cardiology, Odense University Hospital, Odense, Denmark.

Background: The Combo stent (OrbusNeich, Hoevelaken, the Netherlands) combining an abluminal, bioabsorbable polymer eluting sirolimus with a luminal CD34+ antibody to capture endothelial progenitor cells has been developed to further improve safety and efficacy of coronary interventions. We have designed a large-scale registry-based randomized clinical trial to compare the Combo stent to the Orsiro stent (Biotronik, Bülach, Switzerland) in patients undergoing percutaneous coronary intervention.

Methods: The SORT OUT X study will randomly assign 3,140 patients to treatment with Combo or Orsiro stents at 3 sites in Western Denmark. Read More

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http://dx.doi.org/10.1016/j.ahj.2018.04.019DOI Listing
August 2018
2 Reads

Peripheral vascular disease risk in diabetic individuals without coronary heart disease.

Atherosclerosis 2018 Aug 30;275:419-425. Epub 2018 Apr 30.

New York University School of Medicine, Department of Medicine, Division of Cardiology, 227E. 30th Street, TRB rm. 853, New York, NY 10016, USA.

Background And Aims: Diabetes mellitus is a coronary heart disease (CHD) risk-equivalent for the outcome of peripheral vascular disease. The impact of diabetes with comorbid risk factors on the outcome of peripheral vascular disease remains unexplored.

Methods: We performed a cross-sectional analysis of participants in Lifeline Vascular Screening Inc. Read More

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http://dx.doi.org/10.1016/j.atherosclerosis.2018.04.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276116PMC
August 2018
3 Reads

Comparison of coronary artery bypass grafting and percutaneous coronary intervention in patients with heart failure with reduced ejection fraction and multivessel coronary artery disease.

Oncotarget 2018 Apr 20;9(30):21201-21210. Epub 2018 Apr 20.

Department of Cardiac, Vascular and Endovascular Surgery and Transplantology, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia in Katowice, Silesian Center for Heart Diseases, Zabrze, Poland.

Aims: To compare coronary artery bypass grafting (CABG) with percutaneous coronary interventions (PCI) in patients with heart failure with reduced ejection fraction (HFrEF) and multivessel coronary artery disease.

Methods: 1213 patients were selected from institutional databases, 761 and 452 in CABG and PCI group respectively. Only the subjects with left ventricle ejection fraction ≤ 35% and multivessel coronary artery disease were included to the study. Read More

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http://dx.doi.org/10.18632/oncotarget.25006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940397PMC
April 2018
2 Reads

The short- and long-term outcomes of percutaneous intervention with drug-eluting stent vs bare-metal stent in saphenous vein graft disease: An updated meta-analysis of all randomized clinical trials.

Clin Cardiol 2018 May 11;41(5):685-692. Epub 2018 May 11.

Department of Internal Medicine, Hurley Medical Center/Michigan State University, Flint, Michigan.

The use of drug-eluting stents (DES) vs bare-metal stents (BMS) in saphenous vein graft (SVG) lesions remains controversial. We conducted a meta-analysis of all randomized clinical trials comparing the outcomes of DES with BMS in SVG percutaneous coronary interventions. A search of PubMed, Embase, the Cochrane Register of Controlled Trials, and Clinicaltrials. Read More

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http://dx.doi.org/10.1002/clc.22908DOI Listing
May 2018
3 Reads

Effects of Coronary Artery Revascularization with a Polymer-Free Biolimus A9-Coated BioFreedom Stent Versus Bypass Surgery before Noncardiac Surgery.

Yonsei Med J 2018 Jun;59(4):480-488

Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, Korea.

Purpose: The present study aimed to evaluate the efficacy and safety of polymer-free drug-coated BioFreedom stent implantation in comparison to coronary artery bypass graft (CABG) before major noncardiac surgery.

Materials And Methods: In a multicenter registry, 55 patients required revascularization before major noncardiac surgery that should not be delayed >6 months. Of them, 27 underwent BioFreedom stent implantation and 28 underwent CABG. Read More

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http://dx.doi.org/10.3349/ymj.2018.59.4.480DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949289PMC
June 2018
4 Reads

Early and long-term outcomes of complete revascularization with percutaneous coronary intervention in patients with multivessel coronary artery disease presenting with non-ST-segment elevation acute coronary syndromes.

Postepy Kardiol Interwencyjnej 2018 22;14(1):32-41. Epub 2018 Mar 22.

3 Department of Cardiology, Medical University of Silesia in Katowice, School of Medicine in Katowice, Poland.

Introduction: The clinical significance of complete revascularization with percutaneous coronary intervention (CR-PCI) in patients with non-ST-segment acute coronary syndrome (NSTE-ACS) remains uncertain.

Aim: To evaluate the impact of CR-PCI during index hospitalization on short and long-term incidence of death and composite endpoint among patients with multivessel coronary artery disease (CAD) presenting with NSTE-ACS.

Material And Methods: We analyzed consecutive data of 1,592 patients with multivessel CAD from 2006 to 2014. Read More

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http://dx.doi.org/10.5114/aic.2018.74353DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939543PMC
March 2018
2 Reads

Feasibility of cardiovascular magnetic resonance to detect oxygenation deficits in patients with multi-vessel coronary artery disease triggered by breathing maneuvers.

J Cardiovasc Magn Reson 2018 May 7;20(1):31. Epub 2018 May 7.

Department of Anaesthesiology and Pain Medicine, Bern University Hospital, Inselspital, University of Bern, 3010, Bern, Switzerland.

Background: Hyperventilation with a subsequent breath-hold has been successfully used as a non-pharmacological vasoactive stimulus to induce changes in myocardial oxygenation. The purpose of this pilot study was to assess if this maneuver is feasible in patients with multi-vessel coronary artery disease (CAD), and if it is effective at detecting coronary artery stenosis > 50% determined by quantitative coronary angiography (QCA).

Methods: Twenty-six patients with coronary artery stenosis (QCA > 50% diameter stenosis) underwent a contrast-free cardiovascular magnetic resonance (CMR) exam in the time interval between their primary coronary angiography and a subsequent percutaneous coronary intervention (PCI, n = 24) or coronary artery bypass (CABG, n = 2) revascularization procedure. Read More

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http://dx.doi.org/10.1186/s12968-018-0446-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937049PMC
May 2018
5 Reads
4.560 Impact Factor

Implementation of a cardiac PET stress program: comparison of outcomes to the preceding SPECT era.

JCI Insight 2018 May 3;3(9). Epub 2018 May 3.

Intermountain Heart Institute, Intermountain Medical Center, Murray, Utah, USA.

Background: Cardiac positron emission testing (PET) is more accurate than single photon emission computed tomography (SPECT) at identifying coronary artery disease (CAD); however, the 2 modalities have not been thoroughly compared in a real-world setting. We conducted a retrospective analysis of 60-day catheterization outcomes and 1-year major adverse cardiovascular events (MACE) after the transition from a SPECT- to a PET-based myocardial perfusion imaging (MPI) program.

Methods: MPI patients at Intermountain Medical Center from January 2011-December 2012 (the SPECT era, n = 6,777) and January 2014-December 2015 (the PET era, n = 7,817) were studied. Read More

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http://dx.doi.org/10.1172/jci.insight.120949DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6012503PMC
May 2018
2 Reads

Impact of Revascularization on Absolute Myocardial Blood Flow as Assessed by Serial [O]HO Positron Emission Tomography Imaging: A Comparison With Fractional Flow Reserve.

Circ Cardiovasc Imaging 2018 May;11(5):e007417

Department of Cardiology (R.S.D., I.D., W.J.S., S.P.S., A.C.v.R., N.v.R., P.K.)

Background: The main goal of coronary revascularization is to restore myocardial perfusion in case of ischemia, causing coronary artery disease. Yet, little is known on the effect of revascularization on absolute myocardial blood flow (MBF). Therefore, the present prospective study assesses the impact of coronary revascularization on absolute MBF as measured by [O]HO positron emission tomography and fractional flow reserve (FFR) in patients with stable coronary artery disease. Read More

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http://dx.doi.org/10.1161/CIRCIMAGING.117.007417DOI Listing
May 2018
25 Reads

Pre-Angioplasty Instantaneous Wave-Free Ratio Pullback Predicts Hemodynamic Outcome In Humans With Coronary Artery Disease: Primary Results of the International Multicenter iFR GRADIENT Registry.

JACC Cardiovasc Interv 2018 Apr;11(8):757-767

Imperial College London and Hammersmith Hospital NHS Trust, London, United Kingdom. Electronic address:

Objectives: The authors sought to evaluate the accuracy of instantaneous wave-Free Ratio (iFR) pullback measurements to predict post-percutaneous coronary intervention (PCI) physiological outcomes, and to quantify how often iFR pullback alters PCI strategy in real-world clinical settings.

Background: In tandem and diffuse disease, offline analysis of continuous iFR pullback measurement has previously been demonstrated to accurately predict the physiological outcome of revascularization. However, the accuracy of the online analysis approach (iFR pullback) remains untested. Read More

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http://dx.doi.org/10.1016/j.jcin.2018.03.005DOI Listing
April 2018
8 Reads

Peripheral arterial disease: Changes in clinical outcomes and therapeutic strategies in two cohorts, from 2002 to 2008 and from 2008 to 2014. A population-based study.

Eur J Prev Cardiol 2018 Nov 17;25(16):1735-1743. Epub 2018 Apr 17.

1 Laboratory of Cardiovascular Prevention, IRCCS-Istituto di Ricerche Farmacologiche 'Mario Negri', Italy.

Background The aim of our study was to evaluate whether treatments for peripheral artery disease changed in two different cohorts identified in 2002 and 2008, and whether this had an impact on mortality and major clinical outcomes after six years of follow-up. Methods Using administrative health databases of the largest region in Northern Italy, we identified patients admitted to hospital for peripheral artery disease in 2002 and 2008. Both cohorts were followed for six years. Read More

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http://dx.doi.org/10.1177/2047487318770299DOI Listing
November 2018
7 Reads

Patients with non-obstructive coronary artery disease admitted with acute myocardial infarction carry a better outcome compared to those with obstructive coronary artery disease.

Egypt Heart J 2017 Sep 8;69(3):191-199. Epub 2017 May 8.

Kasr Alainy, Department of Cardiology, Cairo University Hospitals, Cairo, Egypt.

Background: The characterization of patients who have acute myocardial infarction (AMI) and insignificant coronary stenosis is unclear.

Aim: The present study aimed to investigate the clinical profile, in-hospital and 3-month outcome of AMI patients with insignificant coronary stenosis in comparison with those with significant disease.

Methods: This prospective observational study included 200 consecutive patients admitted with AMI. Read More

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http://dx.doi.org/10.1016/j.ehj.2017.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5883485PMC
September 2017
7 Reads

[Myocardial revascularization among patients with severe left ventricular dysfunction: a comparison between on-pump beating-heart and off-pump coronary artery bypass grafting].

Zhonghua Wai Ke Za Zhi 2018 Apr;56(4):294-298

Department of Cardiovascular Surgery, Shanghai Institute of Cardiovascular Disease, Zhongshan Hospital, Fudan University, Shanghai 200032, China.

To evaluate the impacts of an on-pump beating-heart versus an off-pump coronary artery bypass grafting (CABG) technique for surgical revascularization on the early clinical outcomes in patients with a left ventricular ejection fraction (EF) of 35% or less. A total of 216 consecutive patients with an echocardiographic estimated EF of 35% or less who underwent non-emergency, primary, isolated CABG from January 2010 to December 2014 at Department of Cardiovascular Surgery, Zhongshan Hospital, Fudan University were included in this study and were divided into either an OBCAB group (patients who received on-pump beating-heart CABG surgery, =88) or an OPCAB group (patients who received off-pump CABG surgery, =128). The early clinical outcomes were investigated and compared. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0529-5815.2018.E010DOI Listing

[Revascularization of left anterior descending artery area using a skeletonized left internal mammary artery: a comparison between sequential and separate grafting].

Zhonghua Yi Xue Za Zhi 2018 Mar;98(10):763-767

Department of Cardiovascular Surgery, Shanghai Institute of Cardiovascular Disease, Zhongshan Hospital, Fudan University, Shanghai 200032, China.

To evaluate in-hospital and mid-term outcomes of sequential versus separate grafting of in situ skeletonized left internal mammary artery (LIMA) to the left coronary system in a single-center, propensity-matched study. After propensity score matching, 120 pairs of patients undergoing first, scheduled, isolated coronary artery bypass grafting (CABG) with in situ skeletonized LIMA grafting to the left anterior descending artery (LAD) territory were entered into a sequential group (sequential grafting of LIMA to the diagonal artery and then to the LAD) or a control group (separate grafting of LIMA to the LAD). The in-hospital and follow-up clinical outcomes and follow-up LIMA graft patency were compared. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2018.10.010DOI Listing

2017 Versus 2012 Appropriate Use Criteria for Percutaneous Coronary Interventions: Impact on Appropriateness Ratings.

JACC Cardiovasc Interv 2018 Mar;11(5):473-478

Department of Medicine, St. Joseph's Health System, Atlanta, Georgia.

Objectives: The purpose of this study is to revisit cases rated as "inappropriate" in the 2012 appropriate use criteria (AUC) using the 2017 AUC.

Background: AUC for coronary revascularization in patients with stable ischemic heart disease (SIHD) were released in January 2017. Earlier 2012 AUC identified a relatively high percentage of New York State patients for whom percutaneous coronary intervention (PCI) was rated as "inappropriate" versus optimal medical therapy alone. Read More

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http://dx.doi.org/10.1016/j.jcin.2018.01.235DOI Listing
March 2018
3 Reads

A multicenter post-marketing evaluation of the Elixir DESolve Novolimus-eluting bioresorbable coronary scaffold system: First results from the DESolve PMCF study.

Catheter Cardiovasc Interv 2018 Nov 6;92(6):1021-1027. Epub 2018 Mar 6.

Department of Cardiology and Angiology, University of Giessen, Medizinische Klinik I, Giessen, Germany.

Objectives: To date, experience with bioresorbable scaffolds (BRS) that elute agents other than everolimus is limited. Thus, a post-marketing clinical follow-up study was conducted to evaluate the continued safety and effectiveness of the DESolve® NOVOLIMUS™ Eluting BRS as treatment for patients with stable coronary artery disease.

Background: The DESolve BRS combines a poly-l-lactide-based backbone with a biodegradable polylactide-based polymer and Novolimus, a macrocyclic lactone mTOR inhibitor. Read More

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http://dx.doi.org/10.1002/ccd.27550DOI Listing
November 2018
10 Reads

Comparison of the Acute and Long-Term Outcomes of Patients With Multivessel Coronary Artery Disease After Angiographic Complete and Incomplete Revascularization With Drug-Eluting Stents.

Circ J 2018 Mar 2;82(4):992-998. Epub 2018 Mar 2.

Division of Cardiology, Department of Medicine and Percutaneous Coronary Intervention Center, Chang Gung Memorial Hospital, Chang Gung University College of Medicine.

Background: Data regarding the long-term outcomes of a large patient population with multivessel coronary artery disease (MV-CAD) after complete revascularization (CR) and incomplete revascularization (IR) with drug-eluting stent (DES) implantation are controversial. The objective of this study was to evaluate differences between the clinical outcomes of CR and IR in such patients.Methods and Results:A total of 1,502 patients with MV-CAD who received DES between April 2005 and August 2016 were enrolled in this study after propensity score matching. Read More

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http://dx.doi.org/10.1253/circj.CJ-17-0812DOI Listing
March 2018
4 Reads

Comparison of drug-eluting balloon versus drug-eluting stent for treatment of coronary artery disease: a meta-analysis of randomized controlled trials.

BMC Cardiovasc Disord 2018 03 2;18(1):46. Epub 2018 Mar 2.

Department of Cardiology, Second Hospital of Jilin University, No. 218 Ziqiang Street, Changchun, 130041, China.

Background: Drug-eluting balloons (DEB) have significant value for treating coronary artery disease (CAD). However, the merits of using DEB versus drug-eluting stents (DES) to treat CAD remain controversial. Herein, we conducted a meta-analysis to compare the safety and efficacy of DEB and DES for treatment of CAD. Read More

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http://dx.doi.org/10.1186/s12872-018-0771-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834842PMC
March 2018
9 Reads

Safety and Effectiveness of Second-Generation Drug-Eluting Stents in Patients With Left Main Coronary Artery Disease.

J Am Coll Cardiol 2018 Feb;71(8):832-841

Department of Cardiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. Electronic address:

Background: Limited data are available on the relative performances between different types of drug-eluting stents (DES) for obstructive left main coronary artery disease (LMCAD).

Objectives: This study sought to compare effectiveness and safety profiles of various second-generation DES for LMCAD in real-world clinical practice.

Methods: Among 4,470 patients in 3, multicenter, prospective registries (IRIS-DES [Interventional Cardiology Research Incorporation Society-Drug-Eluting Stents] registry, the IRIS-MAIN [Interventional Cardiology Research Incorporation Society-Left MAIN Revascularization] registry, and the PRECOMBAT [PREmier of Randomized COMparison of Bypass Surgery versus AngioplasTy Using Drug-Eluting Stent in Patients with Left Main Coronary Artery Disease] study) treated between July 2007 and July 2015, the authors identified 2,692 patients with significant LMCAD who received second-generation DES; 1,254 with cobalt-chromium everolimus-eluting stents (CoCr-EES), 232 with biodegradable polymer biolimus-eluting stents (BP-BES), 616 with platinum-chromium EES (PtCr-EES), and 590 with Resolute zotarolimus-eluting stent (Re-ZES). Read More

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http://dx.doi.org/10.1016/j.jacc.2017.12.032DOI Listing
February 2018
16 Reads

Comparison of three treatment strategies for patients with triple-vessel coronary disease and left ventricular dysfunction.

J Interv Cardiol 2018 Jun 21;31(3):310-318. Epub 2018 Feb 21.

Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.

Introduction: Current guidelines recommend coronary artery bypass grafting (CABG) for patients with multivessel coronary disease and left ventricular (LV) dysfunction. However, some patients undergo percutaneous coronary intervention (PCI) or solely medical therapy (MT) in actual practice. The comparison of long-term outcomes of these three treatment strategies in real world is unclear. Read More

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http://dx.doi.org/10.1111/joic.12497DOI Listing
June 2018
13 Reads

Development of heart failure in patients with rheumatoid arthritis: A Danish population-based study.

Eur J Clin Invest 2018 May 7;48(5):e12915. Epub 2018 Mar 7.

Department of Cardiology, Aarhus University Hospital, Skejby, Denmark.

Background: To investigate the incidence of heart failure (HF) and ischaemic heart disease (IHD) in different time spans following incident rheumatoid arthritis (RA) and, furthermore, to investigate the impact of IHD on the development of HF and the impact of different treatment era of RA.

Materials And Methods: This matched cohort study used nationwide, prospectively collected data. From the total Danish population of approximately 5. Read More

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http://dx.doi.org/10.1111/eci.12915DOI Listing