2,033,535 results match your criteria Comparative medicine[Journal]


C anatomy can evolve via a single developmental change.

Ecol Lett 2018 Dec 17. Epub 2018 Dec 17.

Department of Animal and Plant Sciences, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK.

C photosynthesis is a complex trait that boosts productivity in warm environments. Paradoxically, it evolved independently in numerous plant lineages, despite requiring specialised leaf anatomy. The anatomical modifications underlying C evolution have previously been evaluated through interspecific comparisons, which capture numerous changes besides those needed for C functionality. Read More

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December 2018

Effects of the physician payments sunshine act on the patient experience and perception of care amongst neurosurgeons: A comparative study of online PRW ratings and industry payments.

Clin Neurol Neurosurg 2018 Dec 11;176:127-132. Epub 2018 Dec 11.

Northwestern University Department of Neurosurgery, Feinberg School of Medicine, 676 North St. Clair Street, NMH/Arkes Family Pavilion Suite 2210, Chicago, IL, 60611, United States. Electronic address:

Objective: Growing relationships between industry related financial payments and physicians have become an increasingly controversial topic as they relate to clinical judgment and patient care. Our objective is to analyze and quantify the effects of physician reported industry payments on the patient experience and patient satisfaction as defined by Physician Rating Websites (PRW).

Patients And Methods: We analyzed physician-reported industry payments received by neurosurgeons over four consecutive years as defined by the Physician Payments Sunshine Act (PPSA). Read More

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December 2018

Surgery and protontherapy in Grade I and II skull base chondrosarcoma: A comparative retrospective study.

PLoS One 2018 17;13(12):e0208786. Epub 2018 Dec 17.

AP-HP, Hôpital Lariboisière, Department of Otorhinolaryngology and Paris Diderot University, Paris, France.

Objective: Skull base chondrosarcoma is a rare tumour usually treated by surgery and proton therapy. However, as mortality rate is very low and treatment complications are frequent, a less aggressive therapeutic strategy could be considered. The objective of this study was to compare the results of surgery only vs surgery and adjuvant proton therapy, in terms of survival and treatment adverse effects, based on a retrospective series. Read More

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December 2018

Disaster waste management after the 2016 Kumamoto Earthquake: A mini-review of earthquake waste management and the Kumamoto experience.

Waste Manag Res 2018 Dec 17:734242X18815948. Epub 2018 Dec 17.

3 Ministry of Environment, Japan.

Millions of tons of debris can be generated by natural disasters, impacting the surrounding environment and posing health risks to the public. Proper handling and treatment of such waste is essential to overcome potential hazards as well as to reduce the burden on natural resources during the reconstruction phase. Disaster waste management can have social, economic, and environmental benefits if planned effectively. Read More

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December 2018
1 Read

Cost-Utility Study of the Economics of Bunion Correction Surgery.

Foot Ankle Int 2018 Dec 17:1071100718815663. Epub 2018 Dec 17.

3 Department of Orthopaedics, University of British Columbia, Vancouver, BC, Canada.

Background:: Bunion correction surgery is a very common procedure to improve patients' pain and physical function attributable to a misaligned first metatarsophalangeal joint. The objective of this study was to apply a health utility framework to estimate the cost utility of bunion correction surgery.

Methods:: Patients were prospectively recruited from the population of patients seen in a lower-extremity orthopedic clinic and scheduled for isolated bunion surgery. Read More

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December 2018

Topical hyaluronic acid in the management of oral lichen planus: A comparative study.

J Investig Clin Dent 2018 Dec 17:e12385. Epub 2018 Dec 17.

Department of Oral and Maxillofacial Surgery and Diagnostic Sciences, Jouf University, Sakaka, Saudi Arabia.

Aim: Oral lichen planus (OLP) is a chronic mucocutaneous disorder seen in clinical dental practice. Despite the progress in research and advances in knowledge, the successful management of OLP is still difficult to achieve. The aim of the present study was to compare the therapeutic effects of triamcinolone (TA) preparation (0. Read More

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December 2018

Caudal musculature in ground sharks, Carcharhiniformes, with remarks on their phylogenetic interrelationships.

J Morphol 2019 Jan;280(1):68-77

Departamento de Zoologia, Instituto de Biociências, Universidade de São Paulo, São Paulo, SP, Brazil.

Relationships among families of the shark order Carcharhiniformes are still being debated, for example, in relation to the inclusion of hammerhead sharks (Sphyrnidae) and the tiger shark (Galeocerdo cuvier) in the Carcharhinidae. Previous morphological studies have not analyzed the phylogenetic significance of axial caudal muscles among carcharhiniforms. The authors therefore describe here the axial muscles of the tail region (m. Read More

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January 2019

Morphology and evolution of the wing bullae in South American Leptophlebiidae (Ephemeroptera).

J Morphol 2019 Jan;280(1):95-102

Instituto de Biodiversidad Neotropical (IBN), UNT-CONICET, Cátedra de Biología General, Facultad de Ciencias Naturales, Universidad Nacional de Tucumán, Tucumán, Argentina.

Insects were the first animals to take to the skies, and have been flying for over 320 million years. The order Ephemeroptera is, or at least is part of, the most early-diverging lineage of extant winged insects. The extant species present a very short adult life span, mainly dedicated to reproduction and dispersal of eggs. Read More

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January 2019

Embryogenesis and early larval development in wild-caught Levantine scraper, Capoeta damascina (Valenciennes, 1842).

J Morphol 2019 Jan;280(1):133-148

School of Fisheries, Aquaculture and Aquatic Sciences, Auburn University, Auburn, AL, USA.

Levantine scraper, Capoeta damascina is a candidate species for future stock assessments, conservation studies, and hatchery efforts. Herein, we documented embryonic and early larval development, from egg activation to the exogenous feeding period, using morphological and histological landmarks. Embryos were obtained by in vitro fertilization from hormonally induced wild-caught broodstock, and subsequent development was monitored at temperatures coinciding with native conditions. Read More

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January 2019

Drilling in the dorid species Vayssierea cf. elegans (Gastropoda: Nudibranchia): Functional and comparative morphological aspects.

J Morphol 2019 Jan;280(1):119-132

Invertebrate Zoology Department, Biological Faculty, M.V. Lomonosov Moscow State University, Moscow, Russia.

The drilling mode of feeding is known from two clades of Gastropoda: Caenogastropoda and Heterobranchia. However, the level of convergence and parallelism or homology among these two lineages is unclear. The morphology of the buccal complex is well studied for drilling caenogastropods, but poorly known for drilling nudibranchs. Read More

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January 2019

Minimum Information about an Uncultivated Virus Genome (MIUViG).

Nat Biotechnol 2018 Dec 17. Epub 2018 Dec 17.

US Department of Energy Joint Genome Institute, Walnut Creek, California, USA.

We present an extension of the Minimum Information about any (x) Sequence (MIxS) standard for reporting sequences of uncultivated virus genomes. Minimum Information about an Uncultivated Virus Genome (MIUViG) standards were developed within the Genomic Standards Consortium framework and include virus origin, genome quality, genome annotation, taxonomic classification, biogeographic distribution and in silico host prediction. Community-wide adoption of MIUViG standards, which complement the Minimum Information about a Single Amplified Genome (MISAG) and Metagenome-Assembled Genome (MIMAG) standards for uncultivated bacteria and archaea, will improve the reporting of uncultivated virus genomes in public databases. Read More

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December 2018
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Could we use the erythema grading of the CADESI4 as a simple instrument for future short-duration clinical trials of dogs with atopic dermatitis?

Authors:
Thierry Olivry

Vet Dermatol 2018 Dec 17. Epub 2018 Dec 17.

Department of Clinical Sciences, College of Veterinary Medicine, NC State University, 1060 William Moore Drive, Raleigh, NC, 27607, USA.

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December 2018

Systematic review of ganciclovir pharmacodynamics during the prevention of cytomegalovirus infection in adult solid organ transplant recipients.

Rev Med Virol 2018 Dec 17:e2023. Epub 2018 Dec 17.

Serology and Virology Division, NSW Health Pathology, Prince of Wales Hospital, Sydney, New South Wales, Australia.

Human cytomegalovirus (CMV) represents the most common infection among recipients of solid organ transplants (SOTs). Previous meta-analysis showed 0.8% of SOT recipients developed CMV disease whilst receiving valganciclovir (ValGCV) prophylaxis. Read More

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December 2018

Detecting the Media-adventitia Border in Intravascular Ultrasound Images through a Classification-based Approach.

Ultrason Imaging 2018 Dec 16:161734618820112. Epub 2018 Dec 16.

1 School of Information & Electrical Engineering, Zhejiang University City College, Hangzhou, China.

The detection of the media-adventitia (MA) border in intravascular ultrasound (IVUS) images is essential for vessel assessment and disease diagnosis. However, it remains a challenging task, considering the existence of plaque, calcification, and various artifacts. In this article, an effective method based on classification is proposed to extract the MA border in IVUS images. Read More

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December 2018

[Analysis of medical diagnostic reports (constats) on dental injuries from terminological, dental and forensic medical points of view].

Orv Hetil 2018 Dec;159(51):2154-2161

Általános Orvostudományi Kar, Igazságügyi Orvostani Intézet, Debreceni Egyetem Debrecen.

Writing a constat is a professional skill required of every general physician and dentist. Constats are issued by healthcare providers on the investigating authority's, court's or injured person's request. This document is an official judicial evidence, a record of medical examination, and it is also a medical opinion which can determine the outcome of the subsequent legal process. Read More

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December 2018

Associations among behavioral and psychological symptoms of dementia, care burden, and family-to-work conflict of employed family caregivers.

Geriatr Gerontol Int 2018 Dec 16. Epub 2018 Dec 16.

Department of Family Nursing, Division of Health Sciences & Nursing, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

Aim: The present study aimed to examine the associations among behavioral and psychological symptoms of dementia (BPSD) of persons with dementia (PWD), care burden and family-to-work conflict (FWC) of employed family caregivers.

Method: A cross-sectional study was carried out with employed adult daughter or son (or in-law) caregivers for PWD from two rural cities in Japan. FWC, care burden and the degree of BPSD were evaluated by the Survey Work-Home Interaction-NijmeGen, Zarit Burden Scale-Short Version and Dementia Behavior Disturbance Scale, respectively. Read More

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December 2018

Dermoscopic pre- and posttreatment evaluation in patients with androgenetic alopecia on platelet-rich plasma-A prospective study.

J Cosmet Dermatol 2018 Dec 16. Epub 2018 Dec 16.

Dermatology, Venereology and Leprosy, A. J. Institute of Medical Sciences, Mangalore, India.

Background: Platelet-rich plasma is rich in growth factors that promote differentiation and growth of dermal papilla cells by various signaling pathways. Dermoscopy is handy, bedside tool that helps to improve diagnostic accuracy in various hair disorders.

Objectives: To evaluate and study the role of dermoscopy in patients with androgenetic alopecia (AGA) pre- and posttreatment with platelet-rich plasma (PRP). Read More

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December 2018

Genotype-dependent regulation of vitamin E biosynthesis in olive fruits as revealed through metabolic and transcriptional profiles.

Plant Biol (Stuttg) 2018 Dec 17. Epub 2018 Dec 17.

Department of Agricultural Sciences, Biotechnology & Food Science, Cyprus University of Technology, 3603, Limassol, Cyprus.

Vitamin E is a general term used to describe a group of eight lipophilic compounds known as tocochromanols. These vitamin E variants are chemically categorized into two classes formed by α-, β-, γ-, and δ- tocopherols and tocotrienols isoforms, respectively. The present study describes the concurrent regulation of genes and metabolites orchestrating vitamin E biosynthesis in olive drupes of five distinctive Greek olive cultivars. Read More

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December 2018

Applicability of an elastic band exercise program to wheelchair-bound older adults with and without dementia: A self-rating survey.

Geriatr Gerontol Int 2018 Dec 16. Epub 2018 Dec 16.

Master Program of Long-Term Care in Aging, Kaohsiung Medical University, Kaohsiung, Taiwan.

Aim: To investigate the perceptions of wheelchair-bound older adults with and without dementia toward the Wheelchair-bound Senior Elastic Band exercise program, and to compare the differences of their perceptions to the program.

Methods: A descriptive and comparative design was applied. Data were derived from the experimental groups of two cluster-randomized controlled trials. Read More

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December 2018
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Near-Infrared (NIR) Spectrometry as a Fast and Reliable Tool for Fat and Moisture Analyses in Olives.

ACS Omega 2018 Nov 28;3(11):16081-16088. Epub 2018 Nov 28.

Department of Chemistry, Department of Food Science and Technology, and Olive Center, University of California, Davis, California 95616, United States.

The evaluation of fat and moisture contents for olive fruits is crucial for both olive growers and olive oil processors. Reference methods, such as Soxhlet extraction, used for fat content determination in olive fruits are time- and solvent- consuming and labor intensive. Near-infrared (NIR) spectroscopy is proposed as a solution toward rapid and nondestructive analyses of olive fruit fat and moisture contents. Read More

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November 2018

Comparative Studies of White-Rot Fungal Strains ( MTCC-1171 and NCIM-1106) for Effective Degradation and Bioconversion of Ferulic Acid.

ACS Omega 2018 Nov 5;3(11):14858-14868. Epub 2018 Nov 5.

Department of Chemical Engineering, Institute of Chemical Technology, Nathalal Parekh Marg, Matunga, Mumbai 400019, India.

Biodegradation of ferulic acid, by two white-rot fungal strains ( MTCC-1171 and NCIM-1106) was investigated in this study. Both strains could use ferulic acid as a sole carbon source when provided with basal mineral salt medium. achieved complete degradation of ferulic acid (350 mg L) in 20 h, whereas degraded it (250 mg L) in 28 h. Read More

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November 2018

Data on comparative proteomic profiling of human sperm affected by 4-tert-octylphenol in vitro.

Data Brief 2018 Dec 16;21:2242-2245. Epub 2018 Nov 16.

School of Public Health, Southeast University, Nanjing 210009, Jiangsu, China.

This data article presents proteomic profiling and posttranslational modifications of sperm proteins relating to the research paper "4-tert-octylphenol injures motility and viability of human sperm by affecting cAMP-PKA/PKC-tyrosine phosphorylation signals." (Huang et al., 2018). Read More

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December 2018

Is It Actionable? An Evaluation of the Rapid PCR-Based Blood Culture Identification Panel on the Management of Gram-Positive and Gram-Negative Blood Stream Infections.

Open Forum Infect Dis 2018 Dec 11;5(12):ofy308. Epub 2018 Dec 11.

Division of Laboratory Medicine, Mayo Clinic, Phoenix, Arizona.

Background: There is growing interest in the use of rapid blood culture identification (BCID) in antimicrobial stewardship programs (ASPs). Although many studies have looked at its clinical and economic utility, its comparative utility in gram-positive and gram-negative blood stream infections (BSIs) has not been as well characterized.

Methods: The study was a quasi-experimental retrospective study at the Mayo Clinic in Phoenix, Arizona. Read More

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December 2018

in Canadian woodland caribou - Isolation, characterization and suitability for serological tests.

Int J Parasitol Parasites Wildl 2019 Apr 27;8:1-9. Epub 2018 Nov 27.

Direction de la gestion de la faune du Nord-du-Québec, Ministère des Forêts, de la Faune et des Parcs du Québec, 951 boul. Hamel, Chibougamau, Québec, G8P 2Z3, Canada.

In the present study, we report the first isolation of from North America and the second of at all. The parasite was isolated directly from the skin of a Canadian woodland caribou from the migratory ecotype. The animal belonged to the Leaf River Herd, in Northern Quebec, Canada. Read More

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A comparative analysis of socioeconomic inequities in stunting: a case of three middle-income African countries.

Arch Public Health 2018 10;76:77. Epub 2018 Dec 10.

1DST-NRF Centre of Excellence in Food Security, Institute for Social Development, University of the Western Cape, School of Government Building, Robert Sobukwe Road/Private Bag X17, Bellville, 7535 South Africa.

Background: Despite increased economic growth and development, and existence of various policies and interventions aimed at improving food security and nutrition, majority of countries in sub-Saharan Africa have very high levels of child malnutrition. The prevalence of stunting, an indicator of chronic malnutrition, is especially high.

Methods: In this paper, we use Demographic and Health Survey datasets from three countries in the region that obtained middle-income status over the last decade (Ghana, Kenya and Zambia), to provide a comparative quantitative assessment of stunting levels, and examine patterns in stunting inequalities between 2007 and 2014. Read More

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December 2018

EBNA1-targeted inhibitors: Novel approaches for the treatment of Epstein-Barr virus-associated cancers.

Theranostics 2018 22;8(19):5307-5319. Epub 2018 Oct 22.

Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong SAR, China.

Epstein-Barr virus (EBV) infects more than 90% of humans worldwide and establishes lifelong latent infection in the hosts. It is closely associated with endemic forms of a wide range of human cancers and directly contributes to the formation of some. Despite its critical role in cancer development, no EBV- or EBV latent protein-targeted therapy is available. Read More

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October 2018

Proteomic Analysis of Hemocytes During Encapsulation of Sporocysts.

Front Immunol 2018 29;9:2773. Epub 2018 Nov 29.

Department of Pathobiological Sciences, University of Wisconsin, Madison, WI, United States.

Circulating hemocytes of the snail , a major intermediate host for the blood fluke , represent the primary immune effector cells comprising the host's internal defense system. Within hours of miracidial entry into resistant strains, hemocytes infiltrate around developing sporocysts forming multi-layered cellular capsules that results in larval death, typically within 24-48 h post-infection. Using an model of hemocyte-sporocyst encapsulation that recapitulates events, we conducted a comparative proteomic analysis on the responses of hemocytes from inbred strains during the encapsulation of primary sporocysts. Read More

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November 2018

Comparative Microbiome Signatures and Short-Chain Fatty Acids in Mouse, Rat, Non-human Primate, and Human Feces.

Front Microbiol 2018 30;9:2897. Epub 2018 Nov 30.

Department of Internal Medicine-Molecular Medicine, Wake Forest School of Medicine, Center for Diabetes, Obesity and Metabolism, Winston-Salem, NC, United States.

Gut microbiome plays a fundamental role in several aspects of host health and diseases. There has been an exponential surge in the use of animal models that can mimic different phenotypes of the human intestinal ecosystem. However, data on host species-specific signatures of gut microbiome and its metabolites like short-chain fatty acids (SCFAs; i. Read More

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November 2018

Sex-Related Differences in Lactotroph Tumor Aggressiveness Are Associated With a Specific Gene-Expression Signature and Genome Instability.

Front Endocrinol (Lausanne) 2018 30;9:706. Epub 2018 Nov 30.

Centre de Recherche en Cancérologie de Lyon (CRCL), INSERM U1052, CNRS UMR5286, Université de Lyon, Lyon, France.

Sex-related differences have been reported in various cancers, in particular men with lactotroph tumors have a worse prognosis than women. While the underlying mechanism of this sexual dimorphism remains unclear, it has been suggested that a lower estrogen receptor alpha expression may drive the sex differences observed in aggressive and malignant lactotroph tumors that are resistant to dopamine agonists. Based on this observation, we aimed to explore the molecular importance of the estrogen pathway through a detailed analysis of the transcriptomic profile of lactotroph tumors from 20 men and 10 women. Read More

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November 2018

The Calcitonin/Calcitonin Gene-Related Peptide Family in Invertebrate Deuterostomes.

Authors:
Toshio Sekiguchi

Front Endocrinol (Lausanne) 2018 30;9:695. Epub 2018 Nov 30.

Noto Marine Laboratory, Division of Marine Environmental Studies, Institute of Nature and Environmental Technology, Kanazawa University, Kanazawa, Japan.

Calcitonin (CT)/CT gene-related peptide (CGRP) family peptides (CT/CGRP family peptides) including CT, CGRP, adrenomedullin, amylin, and CT receptor-stimulating peptide have been identified from various vertebrates and perform a variety of important physiological functions. These peptides bind to two types of receptors including CT receptor (CTR) and CTR-like receptor (CLR). Receptor recognition of CT/CGRP family peptides is determined by the heterodimer between CTR/CLR and receptor activity-modifying protein (RAMP). Read More

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November 2018

A Detour Task in Four Species of Fishes.

Front Psychol 2018 29;9:2341. Epub 2018 Nov 29.

Center for Mind/Brain Sciences, University of Trento, Rovereto, Italy.

Four species of fish (, , , and ) were tested in a detour task requiring them to temporarily abandon the view of the goal-object (a group of conspecifics) to circumvent an obstacle. Fishes were placed in the middle of a corridor, at the end of which there was an opaque wall with a small window through which the goal was visible. Midline along the corridor two symmetrical apertures allowed animals to access two compartments for each aperture. Read More

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November 2018

Comparative Transcriptome Analysis Between Resistant and Susceptible Rice Cultivars Responding to Striped Stem Borer (SSB), (Walker) Infestation.

Front Physiol 2018 30;9:1717. Epub 2018 Nov 30.

Key Laboratory of Economical and Applied Entomology of Liaoning Province, College of Plant Protection, Shenyang Agricultural University, Shenyang, China.

The striped stem borer, (Walker), is a notorious pest of rice that causes large losses in China. Breeding and screening of resistance rice cultivars are effective strategies for management. In this study, insect-resistant traits of 47 rice cultivars were investigated by artificial infestation (AI) both in field and greenhouse experiments, using the susceptible (S) cultivar 1665 as a control. Read More

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November 2018

Comparative Transcriptome and iTRAQ Proteome Analyses Reveal the Mechanisms of Diapause in Ashmead (Hymenoptera: Aphidiidae).

Front Physiol 2018 30;9:1697. Epub 2018 Nov 30.

Key Laboratory of Integrated Pest Management in Crops, Ministry of Agriculture, Sino-American Biological Control Laboratory, USDA-ARS/Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, China.

Ashmead (Hymenoptera: Aphidiidae) is a solitary endoparasitoid used in the biological control of various aphids. Diapause plays an important role in the successful production and deployment of . Diapause can effectively extend the shelf life of biological control agents and solve several practical production problems like long production cycles, short retention periods, and discontinuities between supply and demand. Read More

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November 2018

Validating the modified System for Evaluation of Teaching Qualities: a teaching quality assessment instrument.

Adv Med Educ Pract 2018 30;9:881-886. Epub 2018 Nov 30.

Anatomy Department, Arabian Gulf University, Manama, Kingdom of Bahrain.

Construct: We assessed the validity of the modified System for Evaluation of Teaching Qualities (mSETQ) in evaluating clinical teachers in Bahrain.

Background: Clinical teacher assessment tools are essential for improving teaching quality. The mSETQ is a teaching quality measurement tool, and demonstrating the validity of this tool could provide a stronger evidence base for the utilization of this questionnaire for assessing medical teachers in Bahrain. Read More

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November 2018

Canine environmental hyperthermia: a case series.

Authors:
Adam Stern

J Vet Med Sci 2018 Dec 14. Epub 2018 Dec 14.

Department of Comparative, Diagnostic, and Population Medicine, College of Veterinary Medicine, University of Florida.

Cases of hyperthermia caused by exposure to high environmental temperature are not uncommonly encountered in dogs. The circumstances surrounding the exposure to high environmental temperature may be accidental or intentional; thus highlighting the importance to perform a forensic autopsy. This report documents three cases of canine environmentally induced hyperthermia and all dogs in this report died less than 6 hrs after exposure to the high environmental temperatures. Read More

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December 2018

Genetic polymorphisms of blood donors in Algeria through blood groups ABO, RH, and Kell.

Transfus Clin Biol 2018 Nov 29. Epub 2018 Nov 29.

Faculty of Sciences, University of Msila, 28000 Msila, Algeria.

Our study included 2465 blood donors unrelated from both sexes, originating from Msila (Algeria), at Msila Blood Transfusion Center (CTS), with the aim of performing an anthropogenetic characterization of the population of M'sila, by studying the three-erythrocyte polymorphic systems ABO, Rhesus, and Kell with their allele frequencies. This allowed us to demonstrate after a multi-varied comparative analysis through principal components analysis (PCA) and hierarchical cluster analysis (HCA) On the one hand, comparing the population of Msila to the different regions of Algeria where we found a genetic proximity with the great south of Algeria going towards the south-east of Algeria. On the other hand, the comparative analysis of Msila's population with other populations in the world based on historical, geographical and cultural profile, by building a tri-hybrid potential parenting model (North Africa, Mediterranean and Middle orient) through the three blood systems, allowed us to identify four potential parents including Egypt and Libya (North Africa) and Saudi Arabia and South Yemen (Middle East), Regarding the third strand of our tri-hybrid model, we did not find any potential parental link with the northern shore of the Mediterranean (southern Europe) despite the historical and geographical link that exists. Read More

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November 2018

Dual-Mobility Constructs in Primary and Revision Total Hip Arthroplasty: A Systematic Review of Comparative Studies.

J Arthroplasty 2018 Nov 17. Epub 2018 Nov 17.

Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN.

Background: Utilization of dual-mobility constructs in total hip arthroplasties (THA) has increased in the recent years. Benefits and risks of these implants in terms of reducing dislocations, long-term survivorship, and associated complications are uncertain when compared to non-dual-mobility articulations.

Methods: A systematic review of prospective and retrospective studies that compared dual-mobility constructs with controls for primary or revision THAs between 1986 and 2018 was performed. Read More

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November 2018

Liposomal Bupivacaine Versus Standard Periarticular Injection in Total Knee Arthroplasty With Regional Anesthesia: A Prospective Randomized Controlled Trial.

J Arthroplasty 2018 Nov 23. Epub 2018 Nov 23.

Department of Orthopedic Surgery, Grant Medical Center, OhioHealth, Columbus, OH.

Background: Liposomal bupivacaine (Exparel) is a long-acting local anesthetic preparation with demonstrated efficacy over placebo in reducing postoperative pain and opioid requirement. Limited comparative efficacy and cost-effectiveness data exist for its use in total knee arthroplasty (TKA) when used in a multimodal, opioid-sparing analgesic and anesthetic approach. We hypothesized that liposomal bupivacaine offers no clinical advantage over our standard of care but carries significant economic impact. Read More

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November 2018

Comparative study of epidermal growth factor and observation only on human subacute tympanic membrane perforation.

Am J Otolaryngol 2018 Nov 27. Epub 2018 Nov 27.

Department of Clinical Medicine, Xinxiang Medical University, Xinxiang City 453003, Henan Province, China.

Objective: To compare the effects of epidermal growth factor (EGF) and observation only on human subacute tympanic membrane perforation (TMP).

Methods: A total of 44 patients with traumatic TMPs >2 months after trauma were divided into an observation group (n = 18) and EGF group (n = 26). Patients in the EGF group underwent direct application of EGF without stripping of the perforation edge. Read More

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November 2018

A randomized, open-label, multicenter, comparative study of therapeutic efficacy, safety and tolerability of BNO 1030 extract, containing Althea root, Cammomile flowers, horsetail herb, walnut leaves, yarrow herb, oak bark, dandelion herb in the treatment of acute non-bacterial tonsillitis in children aged 6 to 18 years.

Am J Otolaryngol 2018 Oct 24. Epub 2018 Oct 24.

Ivano-Frankivsk National Medical University, Galitskaya str. 2, 76000 Ivano-Frankivsk, Ukraine.

Seventy to 95% of acute tonsillitis episodes are caused by viral infection, therefore why antibiotic therapy is not indicated in majority of cases. In such cases, acetaminophen or ibuprofen are used to alleviate the symptoms. The objective of this study was assessment of efficacy of phytoneering extract BNO 1030 (Imupret®) in patients with acute non-bacterial tonsillitis. Read More

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October 2018

Association between miR-21/146a/155 level changes and acute genitourinary radiotoxicity in prostate cancer patients: A pilot study.

Pathol Res Pract 2018 Dec 10. Epub 2018 Dec 10.

Institute for Oncology and Radiology of Serbia, Department of Radiation Oncology, Belgrade, Serbia; Faculty of Medicine, University of Belgrade, Belgrade, Serbia. Electronic address:

Introduction: Nearly sixty percent of patients with prostate cancer (PCa) undergo radiation therapy (RT). During the course of treatment patients may experience normal tissue reactions. It is a well established fact that genetic and epigenetic mechanisms, such as microRNA (miRNA) level changes might be associated with radiotoxicity, as a response to irradiation. Read More

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December 2018

An investigation into the durability of glycemic control in patients with type II diabetes initiated on canagliflozin or sitagliptin: A real-world analysis of electronic medical records.

J Diabetes Complications 2018 Oct 31. Epub 2018 Oct 31.

Janssen Scientific Affairs, LLC, 1125 Trenton-Harbourton Road, Titusville, NJ 08560, USA. Electronic address:

Aims: The aims of this study were to assess glycemic control, weight loss, and durability of glycemic control in patients initiated on canagliflozin (CANA) versus sitagliptin (SITA).

Methods: Adults with type II diabetes mellitus initiated on CANA or SITA (index date) were identified from IQVIA™ Real-World Data Electronic Medical Records - US database (03/29/2012-04/30/2016). Inverse probability of treatment weighting accounted for baseline differences between cohorts. Read More

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October 2018

Cost-effectiveness modelling studies of all preventive measures against rabies: A systematic review.

Vaccine 2018 Dec 13. Epub 2018 Dec 13.

Health Technology Assessment Postgraduate Program, Mahidol University, 447 Sri-Ayuthaya Road, Phaya Thai, Ratchathewi, Bangkok 10400, Thailand; Social Administrative Pharmacy Excellence Research (SAPER) Unit, Department of Pharmacy, Faculty of Pharmacy, Mahidol University, 447 Sri-Ayuthaya Road, Phaya Thai, Ratchathewi, Bangkok 10400, Thailand. Electronic address:

Rabies is one of the most feared infectious diseases worldwide, predominantly occurring in Asia and Africa where rabies is endemic in domestic dog populations. Whereas previous studies have demonstrated mass dog vaccination and post-exposure prophylaxis (PEP) as the most effective control strategies, successful rabies elimination has yet to be realized as these recognized effective interventions continue to face challenges of limited accessibility. In the light of new evidence towards improving programmatic feasibility and clinical practice in rabies control especially among endemic countries, a systematic review was undertaken to identify cost-effectiveness modelling studies of rabies preventive measures and to provide a critical review of published evidence through comparative evaluation and model quality assessment, and a synthesis of key findings based thereon. Read More

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December 2018

A comparative performance analysis of a renowned public private partnership for health care provision in Spain between 2003 and 2015.

Health Policy 2018 Nov 27. Epub 2018 Nov 27.

Health Services and Policy Research Group, Institute for Health Sciences in Aragón, IACS, Aragon, Spain; REDISSEC-Research Network for Health Services on Chronic Patients, Avda. San Juan Bosco 13 (CIBA Building), 50009, Zaragoza, Spain. Electronic address:

Background: Recently, the once archetype of the public private partnership (PPP) in the Spanish National Health System (SNHS), namely the Alzira's Model, has come to an end. Advocates defended the superiority of PPPs over public-tenured provision, in terms of quality and technical efficiency. This paper profiles and compares Alzira's life-cycle performance with similar public-tenured providers. Read More

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November 2018

Extrusion of straight cochlear implant electrodes May be diminished by proximal fixation.

Int J Pediatr Otorhinolaryngol 2019 Jan 3;116:164-167. Epub 2018 Nov 3.

Department of Otolaryngology - Head and Neck Surgery, The Hospital for Sick Children. Toronto, Ontario, Canada; Department of Otolaryngology - Head and Neck Surgery, University of Toronto. Toronto, Ontario, Canada; Archie's Cochlear Implant Laboratory, Hospital for Sick Children, Toronto, Ontario, Canada.

Objectives: To determine if proximal fixation of the cochlear implant helps reduce the rate of straight electrode array extrusion/migration.

Methods: Records of 278 children implanted with a straight electrode at a tertiary pediatric hospital from 1990 to 2017 were reviewed. Demographics, operative reports, electrode type, radiological studies and audiological assessments including impedance and stimulation parameters were collected. Read More

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January 2019

Three-Dimensional Printing in Anatomy Education:Assessing Potential Ethical Dimensions.

Authors:
D Gareth Jones

Anat Sci Educ 2018 Dec 15. Epub 2018 Dec 15.

Department of Anatomy, University of Otago, Dunedin, New Zealand.

New technological developments have frequently had major consequences for anatomy education, and have raised ethical queries for anatomy educators. The advent of three-dimensional (3D) printing of human material is showing considerable promise as an educational tool that fits alongside cadaveric dissection, plastination, computer simulation, and anatomical models and images. At first glance its ethical implications appear minimal, and yet the more extensive ethical implications around clinical bioprinting suggest that a cautious approach to 3D printing in the dissecting room is in order. Read More

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December 2018

Biotechnological potential of bacteria isolated from cattle environments of desert soils in Sonora Mexico.

World J Microbiol Biotechnol 2018 Dec 15;35(1). Epub 2018 Dec 15.

Centro de Investigación en Alimentación y Desarrollo, A.C. Carr. Gustavo Enrique Astiazarán No. 46 AP 1735, CP 83000, Hermosillo, Sonora, Mexico.

The aim of this research was to study the hydrolytic potential of bacteria isolated from cattle environments of two desert soils in one of the driest and hottest zones in America. A total of 26 points were sampled, 144 strains were isolated, and 50 strains were selected for the characterization of esterase, lipase, protease, and amylase activities and for 16S rRNA identification. Strains of the Bacillus, Pseudomonas, Acinetobacter, Enterobacter, Providencia, Escherichia, and Pantoea genera were identified. Read More

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December 2018

Comparative effectiveness of Sumaq and Neem extract cream, Eniloconazole and glycerine iodine on dermatophytosis in Arabian horses: a randomized clinical trial.

Trop Anim Health Prod 2018 Dec 15. Epub 2018 Dec 15.

Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura, 35516, Egypt.

Dermatophytosis is a contagious fungal disease among animal communities. The major concerns of dermatophytosis are cost of treatment, difficulty of control, and the public health consequences. The objective of the present study was to compare the clinical efficacy of Sumaq and Neem extract cream with that of traditional treatments, eniloconazole and glycerine iodine, on dermatophytosis in Arabian horses. Read More

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December 2018

Molecular and NLO Properties of Red Fluorescent Coumarins - DFT Computations Using Long-Range Separated and Conventional Functionals.

J Fluoresc 2018 Dec 15. Epub 2018 Dec 15.

Computational Chemistry Group, Department of Chemistry, Faculty of Science, University of Mauritius, Réduit, 80832, Mauritius.

Comparative study of nonlinear optical properties of red fluorescent coumarins was carried out with density functional theory based ab initio method using the popular global hybrid (GH) and range separated hybrid (RSH) functionals and correlated with the spectroscopic values. The GHs - M06 L, PBE1PBE, M06, BHHLYP, M062X and M06HF and RSHs - HISSbPBE, wB97, wB97X, HSEH1PBE, CAM-B3LYP and wB97XD in combination with the double zeta basis function 6-311 + G(d,p) were used. The computed polarizability (α), hyperpolarizability of the first order (β) and second order (γ) computed by the RSHs are closer to the spectroscopic values compared to GHs. Read More

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December 2018

Comparative analysis of intracellular metabolites, proteins and their molecular functions in a flor yeast strain under two enological conditions.

World J Microbiol Biotechnol 2018 Dec 15;35(1). Epub 2018 Dec 15.

Department of Microbiology, Severo Ochoa (C6) building, Agrifood Campus of International Excellence ceiA3, University of Córdoba, Córdoba, Spain.

Flor yeasts confer a wide range of organoleptic properties to Sherry-type wines during a process called "biological aging" that takes place after alcoholic fermentation. These kinds of yeasts adapt to a biological aging condition by forming a biofilm known as "flor velum" and by changing from fermentative to oxidative metabolism. It has been reported that some functions such as increase of cell surface hydrophobicity or changes to lipid metabolism are enhanced when yeasts switch to biofilm lifestyle. Read More

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December 2018
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